Thomas Hayes, PhD

Title(s)Postdoctoral Scholar, Radiology
SchoolSchool of Medicine
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    1. Hayes TR, Blecha JE, Thompson CM, Gerdes JM, VanBrocklin HF. Divergent synthesis of organophosphate [11C]VX- and [11C]Sarin-surrogates from a common set of starting materials. Appl Radiat Isot. 2019 May 24; 151:182-186. PMID: 31202183.
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    2. Hayes TR, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF. Radiosynthesis of O-(1-[18 F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin. J Labelled Comp Radiopharm. 2018 Dec; 61(14):1089-1094. PMID: 30347484.
      View in: PubMed
    3. Neumann KD, Blecha JE, Hayes TR, Huynh T, Chao CK, Guilloteau N, Zinn KR, VanBrocklin HF, Thompson CM, Gerdes JM. Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [11C]2-Pyridinealdoxime Methiodide ([11C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication. ACS Chem Neurosci. 2018 Dec 19; 9(12):3007-3014. PMID: 30071719.
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    4. Hayes TR, Bottorff SC, Slocumb WS, Barnes CL, Clark AE, Benny PD. Influence of bidentate ligand donor types on the formation and stability in 2 + 1 fac-[MI(CO)3]+ (M = Re, 99mTc) complexes. Dalton Trans. 2017 Jan 24; 46(4):1134-1144. PMID: 28045466.
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    5. Kasten BB, Ma X, Cheng K, Bu L, Slocumb WS, Hayes TR, Trabue S, Cheng Z, Benny PD. Isothiocyanate-Functionalized Bifunctional Chelates and fac-[M(I)(CO)3](+) (M = Re, (99m)Tc) Complexes for Targeting uPAR in Prostate Cancer. Bioconjug Chem. 2016 Jan 20; 27(1):130-42. PMID: 26603218.
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    6. Hayes TR, Lyon PA, Barnes CL, Trabue S, Benny PD. Influence of functionalized pyridine ligands on the radio/chemical behavior of [M(I)(CO)3](+) (M = Re and (99m)Tc) 2 + 1 complexes. Inorg Chem. 2015 Feb 16; 54(4):1528-34. PMID: 25590985.
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    7. Hayes TR, Kasten BB, Barnes CL, Benny PD. Rhenium and technetium bi- and tricarbonyl complexes in a new strategy for biomolecule incorporation using click chemistry. Dalton Trans. 2014 May 21; 43(19):6998-7001. PMID: 24710681; PMCID: PMC4215957.
    8. Kasten BB, Ma X, Liu H, Hayes TR, Barnes CL, Qi S, Cheng K, Bottorff SC, Slocumb WS, Wang J, Cheng Z, Benny PD. Clickable, hydrophilic ligand for fac-[M(I)(CO)3](+) (M = Re/(99m)Tc) applied in an S-functionalized a-MSH peptide. Bioconjug Chem. 2014 Mar 19; 25(3):579-92. PMID: 24568284; PMCID: PMC3983144.
    9. Zhu X, Li J, Hong Y, Kimura RH, Ma X, Liu H, Qin C, Hu X, Hayes TR, Benny P, Gambhir SS, Cheng Z. 99mTc-labeled cystine knot peptide targeting integrin avß6 for tumor SPECT imaging. Mol Pharm. 2014 Apr 07; 11(4):1208-17. PMID: 24524409.
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    10. Hayes TR, Lyon PA, Silva-Lopez E, Twamley B, Benny PD. Photo-initiated thiol-ene click reactions as a potential strategy for incorporation of [M(I)(CO)3]+ (M = Re, (99m)Tc) complexes. Inorg Chem. 2013 Mar 18; 52(6):3259-67. PMID: 23445468.
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