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Thomas James, PhD

TitleProfessor
SchoolUCSF School of Pharmacy
DepartmentPharmaceutical Chemistry
Address600 16th Street
San Francisco CA 94158
Phone415-476-1569
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    Other Positions
    TitleInterim Director, Molecular Design Institute


    Collapse Biography 
    Collapse Awards and Honors
    University of New Mexico, Albuquerque1962  - 1965University Roll of Distinction
    University of New Mexico, Albuquerque1962  - 1965University Honor Roll
    University of New Mexico, Albuquerque1964Kappa Mu Epsilon (Mathematics Honorary)
    Bundesrepublik Deutschlan1964German Award
    University of New Mexico, Albuquerque1964Phi Kappa Phi (Scholastic Honorary)
    University of New Mexico, Albuquerque1965Phi Beta Kappa (Scholastic Honorary)

    Collapse Research 
    Collapse Research Activities and Funding
    Development and Application of In-Cell NMR Techniques
    NIH/NIGMS R21GM066039Aug 1, 2002 - Jul 31, 2005
    Role: Principal Investigator
    ACQUISITION OF AN 800 MHZ NMR SPECTROMETER
    NIH/NCRR S10RR015748Mar 15, 2001 - Sep 14, 2003
    Role: Principal Investigator
    RNA STRUCTURE IN AGILE LOCI OF RIBOSOME AND RETROVIRUSES
    NIH/FIC R03TW001465Feb 9, 2001 - Jan 31, 2005
    Role: Principal Investigator
    THERMODYNAMICS OF PROTEIN-DNA &LIGAND-DNA COMPLEXES
    NIH/FIC R03TW001234Feb 1, 2000 - Jan 31, 2004
    Role: Principal Investigator
    Three-Dimensional HIV RNA Genome Targeted Drug Leads
    NIH/NIAID R01AI046967Jan 1, 2000 - Aug 31, 2012
    Role: Principal Investigator
    TARGETING 4.5S RNA ANTIMICROBIAL DRUG DISCOVERY
    NIH/NIAID R41AI044515Sep 30, 1999 - Sep 29, 2000
    Role: Principal Investigator
    PURCHASE OF Q TOF MASS SPECTROMETER
    NIH/NCRR S10RR012961May 15, 1998 - May 14, 1999
    Role: Principal Investigator
    ACQUISITION OF A 500 MHZ NMR SPECTROMETER CONSOLE
    NIH/NCRR S10RR010490Jun 1, 1996 - May 31, 1997
    Role: Principal Investigator
    SLIPPED LOOP STRUCTURE--A NOVEL POLYNUCLEOTIDE FOLDING
    NIH/FIC R03TW000438Jul 1, 1994 - Jun 30, 1998
    Role: Principal Investigator
    ACQUISITION OF A 600 MHZ NMR SPECTROMETER
    NIH/NCRR S10RR007168May 19, 1992 - Sep 30, 1993
    Role: Principal Investigator
    PROTEIN STRUCTURE VIA ANALYSIS OF 2D NMR SPECTRA
    NIH/NIGMS R01GM041639Jan 1, 1991 - Dec 31, 1994
    Role: Principal Investigator
    High Performance Computing for Biomedical Research
    NIH P41RR006009Sep 1, 1990 - Jul 31, 2013
    Role: Co-Investigator
    OMEGA 500 UPGRADE WITH ARRAY PROCESSOR
    NIH/NCRR S10RR005608Mar 5, 1990 - Mar 4, 1991
    Role: Principal Investigator
    SELF-SHIELDED GRADIENT COILS FOR IN VIVO NMR INSTRUMENT
    NIH/NCRR S10RR004821Jun 14, 1989 - Jun 13, 1990
    Role: Principal Investigator
    SOLUTION STRUCTURE AND DYNAMICS OF NUCLEIC ACIDS
    NIH/NIGMS R01GM039247Feb 1, 1988 - Jun 30, 2002
    Role: Principal Investigator
    CONSOLE FOR IN VIVO MAGNETIC RESONANCE INSTRUMENT
    NIH/NCRR S10RR003841Feb 1, 1988 - Jan 31, 1989
    Role: Principal Investigator
    HIGH-FIELD 500MHZ NMR SPECTROMETER
    NIH/NCRR S10RR003479Jan 15, 1987 - Jan 14, 1988
    Role: Principal Investigator
    IN VIVO NMR SPECTROMETER/IMAGER
    NIH/NCRR S10RR002433Dec 1, 1984 - Nov 30, 1985
    Role: Principal Investigator
    NATIONAL STABLE ISOTOPE RESOURCE AT LOS ALAMOS
    NIH P41RR002231Dec 1, 1983 - Jun 30, 2005
    Role: Co-Investigator
    Pharmaceutical Sciences and Pharmacogenomics
    NIH/NIGMS T32GM007175Jul 1, 1982 - Jun 30, 2022
    Role: Co-Principal Investigator
    Theoretical Studies of Drug/Nucleic Acid Interactions
    NIH/NCI R01CA025644Jan 1, 1980 - Jul 31, 2003
    Role: Principal Investigator
    Resource for Biocomputing, Visualization, and Informatics
    NIH/NCRR P41RR001081Jun 1, 1976 - Sep 14, 2012
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chimenti MS, Bulfer SL, Neitz RJ, Renslo AR, Jacobson MP, James T, Arkin MR, Kelly MJ. A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. J Biomol Screen. 2015 Jul; 20(6):788-800. PMID: 25690569.
      View in: PubMed
    2. Liu J, Segal MR, Kelly MJ, Pelton JG, Kim M, James T, Litt L. 13C NMR metabolomic evaluation of immediate and delayed mild hypothermia in cerebrocortical slices after oxygen-glucose deprivation. Anesthesiology. 2013 Nov; 119(5):1120-36. PMID: 23748856; PMCID: PMC3890426.
    3. Liu J, Sheldon RA, Segal MR, Kelly MJ, Pelton JG, Ferriero DM, James T, Litt L. 1H nuclear magnetic resonance brain metabolomics in neonatal mice after hypoxia-ischemia distinguished normothermic recovery from mild hypothermia recoveries. Pediatr Res. 2013 Aug; 74(2):170-9. PMID: 23708689; PMCID: PMC3734529.
    4. Saraceno M, Massarelli I, Imbriani M, James T, Bianucci AM. Optimizing QSAR models for predicting ligand binding to the drug-metabolizing cytochrome P450 isoenzyme CYP2D6. Chem Biol Drug Des. 2011 Aug; 78(2):236-51. PMID: 21575140.
      View in: PubMed
    5. Liu J, Litt L, Segal MR, Kelly MJ, Yoshihara HA, James T. Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. J Cereb Blood Flow Metab. 2011 Feb; 31(2):547-59. PMID: 20717124; PMCID: PMC3010526.
    6. Chung J, Ulyanov NB, Guilbert C, Mujeeb A, James T. Binding characteristics of small molecules that mimic nucleocapsid protein-induced maturation of stem-loop 1 of HIV-1 RNA. Biochemistry. 2010 Aug 3; 49(30):6341-51. PMID: 20565056; PMCID: PMC2921804.
    7. Ulyanov NB, James T. RNA structural motifs that entail hydrogen bonds involving sugar-phosphate backbone atoms of RNA. New J Chem. 2010 May 1; 34(5):910-917. PMID: 20689681.
      View in: PubMed
    8. Lang PT, Brozell SR, Mukherjee S, Pettersen EF, Meng EC, Thomas V, Rizzo RC, Case DA, James T, Kuntz ID. DOCK 6: combining techniques to model RNA-small molecule complexes. RNA. 2009 Jun; 15(6):1219-30. PMID: 19369428; PMCID: PMC2685511.
    9. Pinto IG, Guilbert C, Ulyanov NB, Stearns J, James T. Discovery of ligands for a novel target, the human telomerase RNA, based on flexible-target virtual screening and NMR. J Med Chem. 2008 Nov 27; 51(22):7205-15. PMID: 18950148; PMCID: PMC2651004.
    10. Liu J, Segal M, Yoo S, Yang GY, Kelly M, James T, Litt L. Antioxidant effect of ethyl pyruvate in respiring neonatal cerebrocortical slices after H(2)O(2) stress. Neurochem Int. 2009 Feb; 54(2):106-10. PMID: 19041675.
      View in: PubMed
    11. Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James T, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G. Perspectives on NMR in drug discovery: a technique comes of age. Nat Rev Drug Discov. 2008 Sep; 7(9):738-45. PMID: 19172689; PMCID: PMC2891904.
    12. Du Z, Fenn S, Tjhen R, James T. Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. J Biol Chem. 2008 Oct 17; 283(42):28757-66. PMID: 18701464; PMCID: PMC2568903.
    13. Chung J, Mujeeb A, Jiang Y, Guilbert C, Pendke M, Wu Y, James T. A small molecule, Lys-Ala-7-amido-4-methylcoumarin, facilitates RNA dimer maturation of a stem-loop 1 transcript in vitro: structure-activity relationship of the activator. Biochemistry. 2008 Aug 5; 47(31):8148-56. PMID: 18616287.
      View in: PubMed
    14. Guilbert C, James T. Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets. J Chem Inf Model. 2008 Jun; 48(6):1257-68. PMID: 18510306; PMCID: PMC2910576.
    15. Du Z, Lee JK, Tjhen R, Stroud RM, James T. Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2391-6. PMID: 18268334; PMCID: PMC2268147.
    16. Zeng J, Liu J, Yang GY, Kelly MJ, James T, Litt L. Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices. Anesthesiology. 2007 Oct; 107(4):630-40. PMID: 17893460.
      View in: PubMed
    17. Ulyanov NB, Shefer K, James T, Tzfati Y. Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates. Nucleic Acids Res. 2007; 35(18):6150-60. PMID: 17827211; PMCID: PMC2094054.
    18. Du Z, Lee JK, Fenn S, Tjhen R, Stroud RM, James T. X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2. RNA. 2007 Jul; 13(7):1043-51. PMID: 17526645; PMCID: PMC1894928.
    19. Du Z, Fenn S, James T. Resonance assignment of the first and second KH (hnRNP-K homology) domains of human poly(C)-binding protein-2 (PCBP2). J Biomol NMR. 2007 Jun; 38(2):197. PMID: 17479348.
      View in: PubMed
    20. Fenn S, Du Z, Lee JK, Tjhen R, Stroud RM, James T. Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res. 2007; 35(8):2651-60. PMID: 17426136; PMCID: PMC1885661.
    21. Mujeeb A, Ulyanov NB, Georgantis S, Smirnov I, Chung J, Parslow TG, James T. Nucleocapsid protein-mediated maturation of dimer initiation complex of full-length SL1 stemloop of HIV-1: sequence effects and mechanism of RNA refolding. Nucleic Acids Res. 2007; 35(6):2026-34. PMID: 17341460; PMCID: PMC1874624.
    22. Mayer M, Lang PT, Gerber S, Madrid PB, Pinto IG, Guy RK, James T. Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA. Chem Biol. 2006 Sep; 13(9):993-1000. PMID: 16984889.
      View in: PubMed
    23. Zeng J, Yang GY, Ying W, Kelly M, Hirai K, James T, Swanson RA, Litt L. Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab. 2007 Feb; 27(2):304-15. PMID: 16736046.
      View in: PubMed
    24. Ulyanov NB, Mujeeb A, Du Z, Tonelli M, Parslow TG, James T. NMR structure of the full-length linear dimer of stem-loop-1 RNA in the HIV-1 dimer initiation site. J Biol Chem. 2006 Jun 9; 281(23):16168-77. PMID: 16603544.
      View in: PubMed
    25. Ulyanov NB, Du Z, James T . Refinement of Nucleic Acid Structures with Residual Dipolar Coupling Restraints in Cartesian Coordinate Space. Modern Magnetic Resonance, Edited by G.A. Webb. Dordrecht: Springer. 2006; 661-666.
    26. Du Z, Lee JK, Tjhen R, Li S, Pan H, Stroud RM, James T. Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A. J Biol Chem. 2005 Nov 18; 280(46):38823-30. PMID: 16186123.
      View in: PubMed
    27. Mayer M, James T. Discovery of ligands by a combination of computational and NMR-based screening: RNA as an example target. Methods Enzymol. 2005; 394:571-87. PMID: 15808238.
      View in: PubMed
    28. James T . Methods in Enzymology, Nuclear Magnetic Resonance of Biological Macromolecules, Vol. 394, 631 pages. New York: Elsevier. 2005.
    29. Lapidot A, Vijayabaskar V, Litovchick A, Yu J, James T. Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy. FEBS Lett. 2004 Nov 19; 577(3):415-21. PMID: 15556620.
      View in: PubMed
    30. Du Z, Yu J, Ulyanov NB, Andino R, James T. Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses. Biochemistry. 2004 Sep 28; 43(38):11959-72. PMID: 15379536.
      View in: PubMed
    31. Du Z, Yu J, Chen Y, Andino R, James T. Specific recognition of the C-rich strand of human telomeric DNA and the RNA template of human telomerase by the first KH domain of human poly(C)-binding protein-2. J Biol Chem. 2004 Nov 12; 279(46):48126-34. PMID: 15331611.
      View in: PubMed
    32. Zeng J, Hirai K, Yang GY, Ying W, Swanson RA, Kelly M, Mayer M, James T, Litt L. Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices. J Bioenerg Biomembr. 2004 Aug; 36(4):415-9. PMID: 15377881.
      View in: PubMed
    33. Du Z, Ulyanov NB, Yu J, Andino R, James T. NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA. Biochemistry. 2004 May 18; 43(19):5757-71. PMID: 15134450.
      View in: PubMed
    34. Hirai K, Hayashi T, Chan PH, Zeng J, Yang GY, Basus VJ, James T, Litt L. PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis. Brain Res Mol Brain Res. 2004 Apr 29; 124(1):51-61. PMID: 15093685.
      View in: PubMed
    35. Kuwata K, Kamatari YO, Akasaka K, James T. Slow conformational dynamics in the hamster prion protein. Biochemistry. 2004 Apr 20; 43(15):4439-46. PMID: 15078089.
      View in: PubMed
    36. Mayer M, James T. NMR-based characterization of phenothiazines as a RNA binding scaffold. J Am Chem Soc. 2004 Apr 7; 126(13):4453-60. PMID: 15053636.
      View in: PubMed
    37. Kuwata K, Matumoto T, Cheng H, Nagayama K, James T, Roder H. NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106-126. Proc Natl Acad Sci U S A. 2003 Dec 9; 100(25):14790-5. PMID: 14657385; PMCID: PMC299804.
    38. Tonelli M, Ulyanov NB, Billeci TM, Karwowski B, Guga P, Stec WJ, James T. Dynamic NMR structures of [Rp]- and [Sp]-phosphorothioated DNA-RNA hybrids: is flexibility required for RNase H recognition? Biophys J. 2003 Oct; 85(4):2525-38. PMID: 14507715; PMCID: PMC1303476.
    39. Du Z, Yu J, Andino R, James T. Extending the family of UNCG-like tetraloop motifs: NMR structure of a CACG tetraloop from coxsackievirus B3. Biochemistry. 2003 Apr 22; 42(15):4373-83. PMID: 12693932.
      View in: PubMed
    40. Litt L, Hirai K, Basus VJ, James T. Temperature control of respiring rat brain slices during high field NMR spectroscopy. Brain Res Brain Res Protoc. 2003 Feb; 10(3):191-8. PMID: 12565690.
      View in: PubMed
    41. Hirai K, Hayashi T, Chan PH, Basus VJ, James T, Litt L. Akt phosphorylation and cell survival after hypoxia-induced cytochrome c release in superfused respiring neonatal rat cerebrocortical slices. Acta Neurochir Suppl. 2003; 86:227-30. PMID: 14753441.
      View in: PubMed
    42. Litt L, Hirai K, Basus VJ, James T. NTP and PCr responses to hypoxia by hypothermic and normothermic respiring, superfused, neonatal rat cerebrocortical slices: an NMR spectroscopy study at 14.1 Tesla. Acta Neurochir Suppl. 2003; 86:71-4. PMID: 14753408.
      View in: PubMed
    43. Comolli LR, Smirnov I, Xu L, Blackburn EH, James T. A molecular switch underlies a human telomerase disease. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):16998-7003. PMID: 12482936; PMCID: PMC139258.
    44. Mayer M, James T. Detecting ligand binding to a small RNA target via saturation transfer difference NMR experiments in D(2)O and H(2)O. J Am Chem Soc. 2002 Nov 13; 124(45):13376-7. PMID: 12418877.
      View in: PubMed
    45. Kuwata K, Li H, Yamada H, Legname G, Prusiner SB, Akasaka K, James T. Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc? Biochemistry. 2002 Oct 15; 41(41):12277-83. PMID: 12369815.
      View in: PubMed
    46. Comolli LR, Ulyanov NB, Soto AM, Marky LA, James T, Gmeiner WH. NMR structure of the 3' stem-loop from human U4 snRNA. Nucleic Acids Res. 2002 Oct 15; 30(20):4371-9. PMID: 12384583; PMCID: PMC137124.
    47. Hirai K, Sugawara T, Chan PH, Basus VJ, James T, Litt L. Cytochrome c associated apoptosis during ATP recovery after hypoxia in neonatal rat cerebrocortical slices. J Neurochem. 2002 Oct; 83(2):309-19. PMID: 12423241.
      View in: PubMed
    48. Macdonald JM, Schmidlin O, James T. In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR. Magn Reson Med. 2002 Sep; 48(3):430-9. PMID: 12210907.
      View in: PubMed
    49. Du Z, Lind KE, James T. Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening. Chem Biol. 2002 Jun; 9(6):707-12. PMID: 12079782.
      View in: PubMed
    50. Ulyanov NB, Bauer WR, James T. High-resolution NMR structure of an AT-rich DNA sequence. J Biomol NMR. 2002 Mar; 22(3):265-80. PMID: 11991355.
      View in: PubMed
    51. Lind KE, Du Z, Fujinaga K, Peterlin BM, James T. Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. Chem Biol. 2002 Feb; 9(2):185-93. PMID: 11880033.
      View in: PubMed
    52. Konerding D, James T, Trump E, Soto AM, Marky LA, Gmeiner WH. NMR structure of a gemcitabine-substituted model Okazaki fragment. Biochemistry. 2002 Jan 22; 41(3):839-46. PMID: 11790105.
      View in: PubMed
    53. James T . The Encyclopedia of Molecular Medicine. Edited by T.E. Creighton. New York: John Wiley & Sons. 2002; 3100-3102.
    54. Tonelli M, Peters RJ, James T, Agard DA. The solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virus. FEBS Lett. 2001 Dec 7; 509(2):161-8. PMID: 11768384.
      View in: PubMed
    55. Kojima C, Ulyanov NB, Kainosho M, James T. Slow motion in the CAA*TTG sequence of a DNA decamer duplex studied by NMR. Biochemistry. 2001 Jun 19; 40(24):7239-46. PMID: 11401571.
      View in: PubMed
    56. Song M, Shao H, Mujeeb A, James T, Miller WL. Molten-globule structure and membrane binding of the N-terminal protease-resistant domain (63-193) of the steroidogenic acute regulatory protein (StAR). Biochem J. 2001 May 15; 356(Pt 1):151-8. PMID: 11336647; PMCID: PMC1221823.
    57. James T. NMR determination of oligonucleotide structure. Curr Protoc Nucleic Acid Chem. 2001 May; Chapter 7:Unit 7.2. PMID: 18428870.
      View in: PubMed
    58. James T, Dötsch V, Schmitz U (Editors). Methods in Enzymology, Nuclear Magnetic Resonance of Biological Macromolecules, Part A, Vol. 338, 480 pages . New York: Academic Press. 2001.
    59. James T, Dötsch V, Schmitz U (Editors). Methods in Enzymology, Nuclear Magnetic Resonance of Biological Macromolecules, Part B, Vol. 339, 454 pages. New York: Academic Press. 2001.
    60. Filikov AV, Mohan V, Vickers TA, Griffey RH, Cook PD, Abagyan RA, James T. Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR. J Comput Aided Mol Des. 2000 Aug; 14(6):593-610. PMID: 10921774.
      View in: PubMed
    61. Serkova N, Litt L, Leibfritz D, Hausen B, Morris RE, James T, Benet LZ, Christians U. The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates. Br J Pharmacol. 2000 Feb; 129(3):485-92. PMID: 10711346; PMCID: PMC1571863.
    62. Görler A, Ulyanov NB, James T. Determination of the populations and structures of multiple conformers in an ensemble from NMR data: multiple-copy refinement of nucleic acid structures using floating weights. J Biomol NMR. 2000 Feb; 16(2):147-64. PMID: 10723994.
      View in: PubMed
    63. James T . Current Protocols in Nucleic Acid Chemistry. Edited by S.L. Beaucage, D.E. Bergstrom, G.D. Glick, and R.A. Jones. New York: John Wiley & Sons, Inc., 7.2. 2000; 1-15.
    64. James T, Lind KE, Filikov, AV, Mujeeb A. Three-Dimensional RNA Structure-Based Drug Discovery. Structure, Motion, Interaction and Expression of Biological Macromolecules. Proc. Eleventh Conversation in Biomolecular Structure & Dynamics. Edited by RH Sarma and MH Sarma. New York: Adenine Press, 11. 2000; 201-205.
    65. James T, Lind KE, Filikov AV, Mujeeb A. Three-dimensional RNA structure-based drug discovery. J Biomol Struct Dyn. 2000; 17 Suppl 1:201-5. PMID: 22607425.
      View in: PubMed
    66. Schmitz U, Behrens S, Freymann DM, Keenan RJ, Lukavsky P, Walter P, James T. Structure of the phylogenetically most conserved domain of SRP RNA. RNA. 1999 Nov; 5(11):1419-29. PMID: 10580470; PMCID: PMC1369863.
    67. Mujeeb A, Parslow TG, Zarrinpar A, Das C, James T. NMR structure of the mature dimer initiation complex of HIV-1 genomic RNA. FEBS Lett. 1999 Sep 24; 458(3):387-92. PMID: 10570946.
      View in: PubMed
    68. Bell TW, Khasanov AB, Drew MG, Filikov A, James T. A Small-Molecule Guanidinium Receptor: The Arginine Cork. Angew Chem Int Ed Engl. 1999 Sep; 38(17):2543-2547. PMID: 10508332.
      View in: PubMed
    69. Schmitz U, James T, Lukavsky P, Walter P. Structure of the most conserved internal loop in SRP RNA. Nat Struct Biol. 1999 Jul; 6(7):634-8. PMID: 10404218.
      View in: PubMed
    70. Serkova N, Litt L, James T, Sadée W, Leibfritz D, Benet LZ, Christians U. Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy. J Pharmacol Exp Ther. 1999 May; 289(2):800-6. PMID: 10215655.
      View in: PubMed
    71. Litt L, Espanol MT, Hasegawa K, Chang LH, Gregory GA, James T, Beal MF, Chan PH. NOS inhibitors decrease hypoxia-induced ATP reductions in respiring cerebrocortical slices. Anesthesiology. 1999 May; 90(5):1392-401. PMID: 10319788.
      View in: PubMed
    72. Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James T. Solution structure of Syrian hamster prion protein rPrP(90-231). Biochemistry. 1999 Apr 27; 38(17):5362-77. PMID: 10220323.
      View in: PubMed
    73. Konerding DE, Cheatham TE, Kollman PA, James T. Restrained molecular dynamics of solvated duplex DNA using the particle mesh Ewald method. J Biomol NMR. 1999 Feb; 13(2):119-31. PMID: 10070753.
      View in: PubMed
    74. Kojima C, Ono A, Kainosho M, James T. Quantitative measurement of transverse and longitudinal cross-correlation between 13C-1H dipolar interaction and 13C chemical shift anisotropy: application to a 13C-labeled DNA duplex. J Magn Reson. 1999 Feb; 136(2):169-75. PMID: 9986759.
      View in: PubMed
    75. Furrer P, Billeci TM, Donati A, Kojima C, Karwowski B, Sierzchala A, Stec W, James T. Structural effect of complete [Rp]-phosphorothioate and phosphorodithioate substitutions in the DNA strand of a model antisense inhibitor-target RNA complex. J Mol Biol. 1999 Jan 29; 285(4):1609-22. PMID: 9917400.
      View in: PubMed
    76. Gmeiner WH, Konerding D, James T. Effect of cytarabine on the NMR structure of a model okazaki fragment from the SV40 genome. Biochemistry. 1999 Jan 26; 38(4):1166-75. PMID: 9930976.
      View in: PubMed
    77. Mujeeb A, Ulyanov NB, Billeci, TM, Farr-Jones S, James T . Structure Computation and Dynamics in Protein NMR, Biological Magnetic Resonance, Edited by LJ Berliner and N Rama Krishna. Vol. 17, New York: Plenum Publ Corp. 1999; 201-222.
    78. Kojima C, Ono A, Kainosho M, James T. DNA duplex dynamics: NMR relaxation studies of a decamer with uniformly 13C-labeled purine nucleotides. J Magn Reson. 1998 Dec; 135(2):310-33. PMID: 9878461.
      View in: PubMed
    79. Schmitz U, Donati A, James T, Ulyanov NB, Yao L. Small structural ensembles for a 17-nucleotide mimic of the tRNA T psi C-loop via fitting dipolar relaxation rates with the quadratic programming algorithm. Biopolymers. 1998 Oct 15; 46(5):329-42. PMID: 9754029.
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    80. Ulyanov NB, Ivanov VI, Minyat EE, Khomyakova EB, Petrova MV, Lesiak K, James T. A pseudosquare knot structure of DNA in solution. Biochemistry. 1998 Sep 15; 37(37):12715-26. PMID: 9737848.
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    81. Tonelli M, Ragg E, Bianucci AM, Lesiak K, James T. Nuclear magnetic resonance structure of d(GCATATGATAG). d(CTATCATATGC): a consensus sequence for promoters recognized by sigma K RNA polymerase. Biochemistry. 1998 Aug 25; 37(34):11745-61. PMID: 9718297.
      View in: PubMed
    82. Tonelli M, James T. Insights into the dynamic nature of DNA duplex structure via analysis of nuclear Overhauser effect intensities. Biochemistry. 1998 Aug 18; 37(33):11478-87. PMID: 9708983.
      View in: PubMed
    83. Baldwin MA, James T, Cohen FE, Prusiner SB. The three-dimensional structure of prion protein: implications for prion disease. Biochem Soc Trans. 1998 Aug; 26(3):481-6. PMID: 9765900.
      View in: PubMed
    84. Mujeeb A, Clever JL, Billeci TM, James T, Parslow TG. Structure of the dimer initiation complex of HIV-1 genomic RNA. Nat Struct Biol. 1998 Jun; 5(6):432-6. PMID: 9628479.
      View in: PubMed
    85. Filikov AV, James T. Structure-based design of ligands for protein basic domains: application to the HIV-1 Tat protein. J Comput Aided Mol Des. 1998 May; 12(3):229-40. PMID: 9749367.
      View in: PubMed
    86. Macdonald JM, Grillo M, Schmidlin O, Tajiri DT, James T. NMR spectroscopy and MRI investigation of a potential bioartificial liver. NMR Biomed. 1998 Apr; 11(2):55-66. PMID: 9608589.
      View in: PubMed
    87. Espanol MT, Litt L, Hasegawa K, Chang LH, Macdonald JM, Gregory G, James T, Chan PH. Fructose-1,6-bisphosphate preserves adenosine triphosphate but not intracellular pH during hypoxia in respiring neonatal rat brain slices. Anesthesiology. 1998 Feb; 88(2):461-72. PMID: 9477067.
      View in: PubMed
    88. James T . Nuclear Magnetic Resonance. Bethesda: Biophysical Society. Ch 1. 1998; 1-31.
    89. Ulyanov NB, Mujeeb A, Donati A, Furrer P, Liu H, Farr-Jones S, Konerding DE, Schmitz U, T.L. James TL. Determination of Structural Ensembles from NMR Data: Conformational Sampling and Probability Assessment. Molecular Modeling and Structure Determination of Nucleic Acids, Symposium Series, Number XX. Edited by NB Leontis and J Santa Lucia. American Chemical Society, Washington, DC. 1998; 181-194.
    90. Schmitz U, Blocker FJH, James T . Oxford Handbook of Nucleic Acid Structure, Edited by S. Neidle. Oxford: Oxford University Press. 1998; 253-294.
    91. Ulyanov NB, Ivanov VI,Minyat EE, Khomyakova EB, Petrova MV, Lesiak K, James T . Structure, Motion, Interaction and Expression of Biological Macromolecules. Proc. Tenth Conversation in Biomolecular Structure & Dynamics. Edited by RH Sarma and MH Sarma. New York: Adenine Press, 75-88. 1998.
    92. Baldwin MA, James T, Cohen FE, Prusiner SB. The Three-Dimensional Structure of PrP: Implications for Prion Disease. Biochemical Soc. Trans. 26. 1998; 481-486.
    93. Lukavsky P, Billeci TM, James T, Schmitz U. NMR Structure Determination of a 28-Nucleotide RNA from the Mammalian Signal Recognition Particle. Molecular Modeling and Structure Determination of Nucleic Acids, ACS Symposium Series, Edited by N.B. Leontis and J. Santa Lucia. American Chemical Society, 122-149. 1998.
    94. A. Donati, C. Rossi, S. Martini, N.B. Ulyanov, and T.L. James. NOE Intensities from Multiple Conformations in Solution Analyzed by the Complete Relaxation Matrix Approach. Appl. Magn. Reson. 1998; 15:401-406.
    95. Donne DG, Viles JH, Groth D, Mehlhorn I, James T, Cohen FE, Prusiner SB, Wright PE, Dyson HJ. Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible. Proc Natl Acad Sci U S A. 1997 Dec 9; 94(25):13452-7. PMID: 9391046; PMCID: PMC28326.
    96. Peretz D, Williamson RA, Matsunaga Y, Serban H, Pinilla C, Bastidas RB, Rozenshteyn R, James T, Houghten RA, Cohen FE, Prusiner SB, Burton DR. A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. J Mol Biol. 1997 Oct 31; 273(3):614-22. PMID: 9356250.
      View in: PubMed
    97. James T, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE. Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19):10086-91. PMID: 9294167; PMCID: PMC23313.
    98. Kaneko K, Zulianello L, Scott M, Cooper CM, Wallace AC, James T, Cohen FE, Prusiner SB. Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation. Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19):10069-74. PMID: 9294164; PMCID: PMC23307.
    99. Kuwata K, Liu H, Schleich T, James T. Rotational correlation times of internuclear vectors in a DNA duplex with G-A mismatch determined in aqueous solution by complete relaxation matrix analysis of off-resonance ROESY (O-ROESY) spectra. J Magn Reson. 1997 Sep; 128(1):70-81. PMID: 9345778.
      View in: PubMed
    100. Sorensen MD, Bjorn S, Norris K, Olsen O, Petersen L, James T, Led JJ. Solution structure and backbone dynamics of the human alpha3-chain type VI collagen C-terminal Kunitz domain,. Biochemistry. 1997 Aug 26; 36(34):10439-50. PMID: 9265624.
      View in: PubMed
    101. Yao LJ, James T, Kealey JT, Santi DV, Schmitz U. The dynamic NMR structure of the T psi C-loop: implications for the specificity of tRNA methylation. J Biomol NMR. 1997 Apr; 9(3):229-44. PMID: 9204554.
      View in: PubMed
    102. Zhang H, Stockel J, Mehlhorn I, Groth D, Baldwin MA, Prusiner SB, James T, Cohen FE. Physical studies of conformational plasticity in a recombinant prion protein. Biochemistry. 1997 Mar 25; 36(12):3543-53. PMID: 9132005.
      View in: PubMed
    103. Mujeeb A, Reynolds MA, James T. High-resolution NMR of an antisense DNA x RNA hybrid containing alternating chirally pure Rp methylphosphonates in the DNA backbone. Biochemistry. 1997 Mar 4; 36(9):2371-9. PMID: 9054542.
      View in: PubMed
    104. Litt L, Espanol MT, Xu Y, Cohen Y, Chang L-H, P.R. Weinstein PR, Chan PH, James T, Respiring Rat Brain Slices: Model Studies of Hypoxia, Ischemia, and Excitotoxicity. . NMR Spectroscopy of Biomolecules, Edited by J.L. Markley and S.J. Opella. New York: Oxford University Press, 340-357. 1997.
    105. Schmitz U, Freymann DM, James T, Keenan RJ, Vinayak R, Walter P. NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP). RNA. 1996 Dec; 2(12):1213-27. PMID: 8972771; PMCID: PMC1369449.
    106. Liu H, Tonelli M, James T. Correcting NOESY cross-peak intensities for partial relaxation effects enabling accurate distance information. J Magn Reson B. 1996 Apr; 111(1):85-9. PMID: 8620288.
      View in: PubMed
    107. Mujeeb A, Parslow TG, Yuan YC, James T. Aqueous solution structure of a hybrid lentiviral Tat peptide and a model of its interaction with HIV-1 TAR RNA. J Biomol Struct Dyn. 1996 Feb; 13(4):649-60. PMID: 8906885.
      View in: PubMed
    108. Baldwin MA, Zhang H, Bekker T, Zhou S, Nguyen JT, Kolbert AC, Heller J, James T, Wemmer DE, Pines A, Cohen FE, Prusiner SB. Synthetic Peptides Model a-helix-b-sheet Conformational Changes in the Prion Protein. Peptides: Chemistry, Structure and Biology, Edited by P.T.P. Kaumaya and R.S. Hodges. Leiden: ESCOM Science Publishers B.V., 468-470. 1996.
    109. T.L. James TL, Gonzalez C, Liu, H, Schmitz U, Ulyanov NB. Dynamic Structure of Nucleic Acid Duplexes. NMR as a Structural Tool for Macromolecules: Current Status and Future Directions, Edited by B.D. Nageswara Rao and M.D. Kemple. New York: Plenum Publishing Corp., 191-206. 1996.
    110. Schmitz U, Gonzales C, Ulyanov NB, Blocker, FH, Liu H, James T . Biological Structure and Dynamics, Proceedings of the Ninth Conversation in Biomolecular Structure and Dynamics. Edited by R.H. Sarma and M.H. Sarma. New York: Adenine Press, Vol. 2, 165-187. 1996.
    111. Espanol MT, Litt L, Chang LH, James T, Weinstein PR, Chan PH. Adult rat brain-slice preparation for nuclear magnetic resonance spectroscopy studies of hypoxia. Anesthesiology. 1996 Jan; 84(1):201-10. PMID: 8572333.
      View in: PubMed
    112. Liu H, Spielmann HP, Ulyanov NB, Wemmer DE, James T. Interproton distance bounds from 2D NOE intensities: effect of experimental noise and peak integration errors. J Biomol NMR. 1995 Dec; 6(4):390-402. PMID: 8563467.
      View in: PubMed
    113. Zhang H, Kaneko K, Nguyen JT, Livshits TL, Baldwin MA, Cohen FE, James T, Prusiner SB. Conformational transitions in peptides containing two putative alpha-helices of the prion protein. J Mol Biol. 1995 Jul 21; 250(4):514-26. PMID: 7542350.
      View in: PubMed
    114. González C, Stec W, Reynolds MA, James T. Structure and dynamics of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety: NMR and molecular dynamics with conventional and time-averaged restraints. Biochemistry. 1995 Apr 18; 34(15):4969-82. PMID: 7711019.
      View in: PubMed
    115. Liu H, Banville DL, Basus VJ, James T. Deriving accurate interproton distances from ROESY spectra with limited knowledge of scalar coupling constants via the CARNIVAL algorithm. An iterative complete-relaxation-matrix approach. J Magn Reson B. 1995 Apr; 107(1):51-9. PMID: 7743074.
      View in: PubMed
    116. Ulyanov NB, James T. Statistical analysis of DNA duplex structural features. Methods Enzymol. 1995; 261:90-120. PMID: 8569515.
      View in: PubMed
    117. Ulyanov NB, Schmitz U, Kumar A, James T. Probability assessment of conformational ensembles: sugar repuckering in a DNA duplex in solution. Biophys J. 1995 Jan; 68(1):13-24. PMID: 7711233; PMCID: PMC1281656.
    118. Schmitz U, James T. How to generate accurate solution structures of double-helical nucleic acid fragments using nuclear magnetic resonance and restrained molecular dynamics. Methods Enzymol. 1995; 261:3-44. PMID: 8569500.
      View in: PubMed
    119. James T . Methods in Enzymology, Nuclear Magnetic Resonance and Nucleic Acids, Vol. 261, 644 pages. New York: Academic Press. 1995.
    120. James T . Encyclopedia of Nuclear Magnetic Resonance. Edited by D.M. Grant and R.K. Harris. New York: John Wiley & Sons, 3320-3331. 1995.
    121. Ulyanov NB, James T . Methods in Enzymology, Nuclear Magnetic Resonance and Nucleic Acids. Edited by T.L. James. New York: Academic Press, Vol. 261. 1995; 90-121.
    122. James T . Encyclopedia of Nuclear Magnetic Resonance. Edited by D.M. Grant and R.K. Harris. New York: John Wiley & Sons. 1995.
    123. Schmitz U, James T . Methods in Enzymology, Nuclear Magnetic Resonance and Nucleic Acids, Edited by T.L. James. New York: Academic Press, Vol. 261, 3-44. 1995.
    124. Ulyanov NB, Bishop KD, Ivanov VI, James T. Tertiary base pair interactions in slipped loop-DNA: an NMR and model building study. Nucleic Acids Res. 1994 Oct 11; 22(20):4242-9. PMID: 7937152; PMCID: PMC331933.
    125. González C, Stec W, Kobylanska A, Hogrefe RI, Reynolds M, James T. Structural study of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety by NMR: extraction of distance and torsion angle constraints and imino proton exchange rates. Biochemistry. 1994 Sep 20; 33(37):11062-72. PMID: 7537083.
      View in: PubMed
    126. Mujeeb A, Bishop K, Peterlin BM, Turck C, Parslow TG, James T. NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 Tat. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8248-52. PMID: 8058789; PMCID: PMC44583.
    127. Espanol MT, Litt L, Xu Y, Chang LH, James T, Weinstein PR, Chan PH. 19F NMR calcium changes, edema and histology in neonatal rat brain slices during glutamate toxicity. Brain Res. 1994 May 30; 647(1):172-6. PMID: 7915186.
      View in: PubMed
    128. Espanol MT, Xu Y, Litt L, Yang GY, Chang LH, James T, Weinstein P, Chan PH. Modulation of glutamate-induced intracellular energy failure in neonatal cerebral cortical slices by kynurenic acid, dizocilpine, and NBQX. J Cereb Blood Flow Metab. 1994 Mar; 14(2):269-78. PMID: 7906691.
      View in: PubMed
    129. Kurhanewicz J, Char DH, Stauffer P, Quivey JM, James T. 31P magnetic resonance spectroscopy after combined hyperthermia and radiation. Curr Eye Res. 1994 Feb; 13(2):151-6. PMID: 8194362.
      View in: PubMed
    130. Bishop KD, Blocker FJ, Egan W, James T. Hepatitis B virus direct repeat sequence: imino proton exchange rates and distance and torsion angle restraints from NMR. Biochemistry. 1994 Jan 18; 33(2):427-38. PMID: 8286373.
      View in: PubMed
    131. Weisz K, Shafer RH, Egan W, James T. Solution structure of the octamer motif in immunoglobulin genes via restrained molecular dynamics calculations. Biochemistry. 1994 Jan 11; 33(1):354-66. PMID: 8286357.
      View in: PubMed
    132. Espanol MT, Xu Y, Litt L, Chang LH, James T, Weinstein PR, Chan PH. Modulation of edema by dizocilpine, kynurenate, and NBQX in respiring brain slices after exposure to glutamate. Acta Neurochir Suppl (Wien). 1994; 60:58-61. PMID: 7976656.
      View in: PubMed
    133. James T. Assessment of quality of derived macromolecular structures. Methods Enzymol. 1994; 239:416-39. PMID: 7830593.
      View in: PubMed
    134. Imaizumi S, Chang L, Cohen Y, Chan PH, Weinstein PR, Yoshimoto T, James T. Reduction of superoxide dismutase activity correlates with visualization of edema by T2-weighted MR imaging in focal ischemic rat brain. Neurol Med Chir (Tokyo). 1994 Jan; 34(1):1-9. PMID: 7514745.
      View in: PubMed
    135. Baldwin MA, Nguyen JT, Zhang H, Pan KM, Huang Z, Livshits TL, Kaneko K, Cohen FE, James T, Prusiner SB. Conformational Changes in the Prion Protein Can be Simulated with Synthetic Peptides. . Proceedings of the Twenty-Third European Peptide Symposium. Edited by H.L.S. Maia, Leiden: ESCOM Science Publishers B.V., 580-581. 1994.
    136. James T . Methods in Enzymology, Nuclear Magnetic Resonance, Part C. Edited by T.L. James and N.J. Oppenheimer. New York: Academic Press, Vol. 239. 1994; 416-439.
    137. James T, Bishop KD, Blocker F, Gonzalez C, Kumar A, Liu H, Mujeeb A, Schmitz U, Ulyanov NB, Yuan Y-C, Weisz K. Determination of High-Resolution, Sequence-Dependent DNA Duplex Structures in Solution. Study of Biological Macromolecules by Nuclear Magnetic Resonance Spectroscopy. Edited by C.L. Stassinopoulou. NATO ASI Series Volume. Berlin: Springer-Verlag , Vol H87. 1994; 335-348.
    138. James T, 116, 9412. Book Review on "Nucleic Acid Targeted Drug Design. Edited by C.L. Propst and T.J. Perun. New York: Marcel Dekker, 1992". 1994.
    139. James T, Oppenheimer NJ (Editors). Methods in Enzymology, Nuclear Magnetic Resonance, Part C. Vol 239, 813 pages. New York: Academic Press. 1994.
    140. James, T.L. Computational Strategies Pertinent to NMR Solution Structure Determination. Current Opinion in Structural Biology. 1994; 4:275-284.
    141. James T . Structural Biology: The State of the Art. Proc. Eighth Conversation in Biomolecular Structure & Dynamics. Vol. 2, pp. 251-272. Edited by R.H. Sarma and M.H. Sarma. New York: Adenine Press. 1994.
    142. Mujeeb A, Kerwin SM, Kenyon GL, James T. Solution structure of a conserved DNA sequence from the HIV-1 genome: restrained molecular dynamics simulation with distance and torsion angle restraints derived from two-dimensional NMR spectra. Biochemistry. 1993 Dec 14; 32(49):13419-31. PMID: 8257678.
      View in: PubMed
    143. Schmitz U, Ulyanov NB, Kumar A, James T. Molecular dynamics with weighted time-averaged restraints for a DNA octamer. Dynamic interpretation of nuclear magnetic resonance data. J Mol Biol. 1993 Nov 20; 234(2):373-89. PMID: 8230221.
      View in: PubMed
    144. Ulyanov NB, Schmitz U, James T. Metropolis Monte Carlo calculations of DNA structure using internal coordinates and NMR distance restraints: an alternative method for generating a high-resolution solution structure. J Biomol NMR. 1993 Sep; 3(5):547-68. PMID: 8219740.
      View in: PubMed
    145. Litt L, Xu Y, Cohen Y, James T. Nonmagnetic hyperbaric chamber for in vivo NMR spectroscopy studies of small animals. Magn Reson Med. 1993 Jun; 29(6):812-6. PMID: 8350725.
      View in: PubMed
    146. Shimizu H, Graham SH, Chang LH, Mintorovitch J, James T, Faden AI, Weinstein PR. Relationship between extracellular neurotransmitter amino acids and energy metabolism during cerebral ischemia in rats monitored by microdialysis and in vivo magnetic resonance spectroscopy. Brain Res. 1993 Mar 5; 605(1):33-42. PMID: 8096789.
      View in: PubMed
    147. Bretan PN, Vigneron DB, Hricak H, Price DC, Yen TS, Luo JA, Tanagho EA, James T. Assessment of in situ renal transplant viability by 31P-MRS: experimental study in canines. Am Surg. 1993 Mar; 59(3):182-7. PMID: 8386489.
      View in: PubMed
    148. Kurhanewicz J, Dahiya R, Macdonald JM, Chang LH, James T, Narayan P. Citrate alterations in primary and metastatic human prostatic adenocarcinomas: 1H magnetic resonance spectroscopy and biochemical study. Magn Reson Med. 1993 Feb; 29(2):149-57. PMID: 8429778.
      View in: PubMed
    149. Macdonald JM, Kurhanewicz J, Dahiya R, Espanol MT, Chang LH, Goldberg B, James T, Narayan P. Effect of glucose and confluency on phosphorus metabolites of perfused human prostatic adenocarcinoma cells as determined by 31P MRS. Magn Reson Med. 1993 Feb; 29(2):244-8. PMID: 8429789.
      View in: PubMed
    150. James T, Kerwood DJ, Gochin M, Mills PA, Borgias BA, Basus VJ. Refinement of Three-Dimensional Protein and DNA Structures in Solution from Two-Dimensional NMR Spectra. New Methods in Drug Research, Vol. 4. Edited by A. Makriannis. Barcelona: Prous. 1993.
    151. Liu, H., Weisz, K. and James, T.L. Tailored Excitation by Shaped RF Pulses: Optimization and Implementation of Excitation Containing a Notch. J. Magn. Reson. 1993.
    152. Liu, H., Kumar,A., Weisz,K., Schmitz, U., Bishop, K.D., and James, T.L. . Extracting Accurate Distances and Bounds from 2D NOE Exchangeable Proton Peaks. J. Am. Chem Soc. 1993; 115:1590-1591.
    153. Mills PA, Rashid A, James T. Monte Carlo calculations of ion distributions surrounding the oligonucleotide d(ATATATATAT)2 in the B, A, and wrinkled D conformations. Biopolymers. 1992 Nov; 32(11):1491-501. PMID: 1457729.
      View in: PubMed
    154. Espanol MT, Litt L, Yang GY, Chang LH, Chan PH, James T, Weinstein PR. Tolerance of low intracellular pH during hypercapnia by rat cortical brain slices: A 31P/1H NMR study. J Neurochem. 1992 Nov; 59(5):1820-8. PMID: 1402924.
      View in: PubMed
    155. Chang LH, Shimizu H, Abiko H, Swanson RA, Faden AI, James T, Weinstein PR. Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats. J Cereb Blood Flow Metab. 1992 Nov; 12(6):1030-8. PMID: 1356994.
      View in: PubMed
    156. Mujeeb A, Kerwin SM, Egan W, Kenyon GL, James T. A potential gene target in HIV-1: rationale, selection of a conserved sequence, and determination of NMR distance and torsion angle constraints. Biochemistry. 1992 Oct 6; 31(39):9325-38. PMID: 1327112.
      View in: PubMed
    157. Schmitz U, Sethson I, Egan WM, James T. Solution structure of a DNA octamer containing the Pribnow box via restrained molecular dynamics simulation with distance and torsion angle constraints derived from two-dimensional nuclear magnetic resonance spectral fitting. J Mol Biol. 1992 Sep 20; 227(2):510-31. PMID: 1404366.
      View in: PubMed
    158. Weisz K, Shafer RH, Egan W, James T. The octamer motif in immunoglobulin genes: extraction of structural constraints from two-dimensional NMR studies. Biochemistry. 1992 Aug 25; 31(33):7477-87. PMID: 1510934.
      View in: PubMed
    159. Stolarski R, Egan W, James T. Solution structure of the EcoRI DNA octamer containing 5-fluorouracil via restrained molecular dynamics using distance and torsion angle constraints extracted from NMR spectral simulations. Biochemistry. 1992 Aug 11; 31(31):7027-42. PMID: 1643037.
      View in: PubMed
    160. Kurhanewicz J, Dahiya R, Macdonald JM, Jajodia P, Chang LH, James T, Narayan P. Phosphorus metabolite characterization of human prostatic adenocarcinoma in a nude mouse model by 31P magnetic resonance spectroscopy and high pressure liquid chromatography. NMR Biomed. 1992 Jul-Aug; 5(4):185-92. PMID: 1449954.
      View in: PubMed
    161. Wendland MF, Iyer SB, Fu KK, Lam KN, James T. Correlations between in vivo 31P MRS measurements, tumor size, cell survival, and hypoxic fraction in the murine EMT6 tumor. Magn Reson Med. 1992 Jun; 25(2):217-32. PMID: 1614307.
      View in: PubMed
    162. Widmer H, Abiko H, Faden AI, James T, Weinstein PR. Effects of hyperglycemia on the time course of changes in energy metabolism and pH during global cerebral ischemia and reperfusion in rats: correlation of 1H and 31P NMR spectroscopy with fatty acid and excitatory amino acid levels. J Cereb Blood Flow Metab. 1992 May; 12(3):456-68. PMID: 1569139.
      View in: PubMed
    163. Hu SH, Weisz K, James T, Shafer RH. H-NMR studies on d(GCTTAAGC)2 and its complex with berenil. Eur J Biochem. 1992 Feb 15; 204(1):31-8. PMID: 1740143.
      View in: PubMed
    164. Thomas, M.A., Narayan, P., Kurhanewicz, J., Jajodia, P., James, T.L., and Weiner, M. Detection of Phosphorus Metabolites in Human Prostrates with a Transrectal Phosphorus-31 NMR Probe. J. Magn. Reson. 1992; 99:377-386.
    165. Kumar, A., James, T.L., and Levy, G.C. Macromolecule Structure Refinement by Relaxation Matrix Analysis of 2D NOE Spectra: Effect of Differential Internal Motion on Internuclear Distance Determination in Proteins. Israel J. of Chem. 1992; 32:257-261.
    166. Schmitz, U.,Kumar, A. and James, T.L. Dynamic Interpretation of NMR Data: Molecular Dynamics with Weighted Time-Averaged Restraints and Ensemble R-Factor. J. Am. Chem. Soc. 1992; 114:10654-10655.
    167. Liu, H., Thomas, P.D., and James, T.L. Averaging of Cross-Relaxation Rates and Distances for Methyl, Methylene and Aromatic Ring Protons Due to Motion or Overlap: Extraction of Accurate Distances Iteratively via Relaxation Matrix Analysis of 2D NOE Spectra. J. Magn. Reson. 1992; 98:163-175.
    168. James, TL. Refinement of Three-Dimensional Biopolymer Structures in Solution Using NMR Data. Chemical Design Automation News. 1992; 7:19-27.
    169. Smith V, Kurhanewicz J, James T . Solvent-Suppression Pulses. III. Design Using Simulated-Annealing Optimization with in Vitro and in Vivo Testing. J Magn Reson. 1992; 96:345-362.
    170. Chang L-H, James T . Biol Magn Reson, Edited by L.J. Berliner and J. Reuben. New York: Plenum Press. 1992; 135-158.
    171. Kurhanewicz J, Thomas A, Jajodia P, Weiner MW, James T, Vigneron DB, Narayan P. 31P spectroscopy of the human prostate gland in vivo using a transrectal probe. Magn Reson Med. 1991 Dec; 22(2):404-13. PMID: 1725918.
      View in: PubMed
    172. Xu Y, Cohen Y, Litt L, Chang LH, James T. Tolerance of low cerebral intracellular pH in rats during hyperbaric hypercapnia. Stroke. 1991 Oct; 22(10):1303-8. PMID: 1926243.
      View in: PubMed
    173. Schmitz U, Pearlman DA, James T. Solution structure of [d(GTATATAC)]2 via restrained molecular dynamics simulations with nuclear magnetic resonance constraints derived from relaxation matrix analysis of two-dimensional nuclear Overhauser effect experiments. J Mol Biol. 1991 Sep 5; 221(1):271-92. PMID: 1920410.
      View in: PubMed
    174. Narayan P, Jajodia P, Kurhanewicz J, Thomas A, MacDonald J, Hubesch B, Hedgcock M, Anderson CM, James T, Tanagho EA. Characterization of prostate cancer, benign prostatic hyperplasia and normal prostates using transrectal 31phosphorus magnetic resonance spectroscopy: a preliminary report. J Urol. 1991 Jul; 146(1):66-74. PMID: 1711587.
      View in: PubMed
    175. Winguth S, Kurhanewicz J, Wang ML, Quivey JM, James T, Char DH. 31P magnetic resonance spectroscopy (MRS) of experimental orbital myositis. Invest Ophthalmol Vis Sci. 1991 Jul; 32(8):2417-22. PMID: 2071353.
      View in: PubMed
    176. Kerwood DJ, Zon G, James T. Structure determination of [d(ATATATAUAT)]2 via two-dimensional NOE spectroscopy and molecular dynamics calculations. Eur J Biochem. 1991 May 8; 197(3):583-95. PMID: 2029892.
      View in: PubMed
    177. Thomas PD, Basus VJ, James T. Protein solution structure determination using distances from two-dimensional nuclear Overhauser effect experiments: effect of approximations on the accuracy of derived structures. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1237-41. PMID: 1996325; PMCID: PMC50992.
    178. Cohen Y, Sanada T, Pitts LH, Chang LH, Nishimura MC, Weinstein PR, Litt L, James T. Surface coil spectroscopic imaging: time and spatial evolution of lactate production following fluid percussion brain injury. Magn Reson Med. 1991 Jan; 17(1):225-36. PMID: 2067397.
      View in: PubMed
    179. James T, Gochin M, Kerwood DJ, Pearlman DA, Schmitz U, Thomas PD. Refinement of Three-Dimensional Protein and DNA Structures in Solution from NMR Data. Computational Aspects of the Study of Biological Macromolecules by NMR. Edited by J.C. Hoch, F.M. Poulsen, and D. Redfield. NATO ASI Series, Vol. 225. New York: Plenum Press. 1991; 331-347.
    180. Litt L, Lockhart S, Cohen Y, Yasuda N, Kim F, Freire B, Laster M, Peterson N, Taheri S, Chang L-H, Sessler DI, Moseley M, Eger II EI, James T, Isoflurane, and Desflurane: Rapid Elimination and No Abundant Saturable Binding. Ann NY Acad Sci, 625,. 1991; 707-724.
    181. James T, Basus VJ. Generation of High-Resolution Protein Structures in Solution from Multidimensional NMR. Ann. Rev. Phys. Chem. 42, 501-542. 1991.
    182. Naderi HM, Thomason JF, Borgias BA, Anderson S, James T, I.D. Kuntz ID. 1H NMR Assignments and Three-Dimensional Structure of Ala14/Ala38 Bovine Pancreatic Trypsin Inhibitor Based on Two-Dimensional NMR and Distance Geometry. Conformations and Forces in Protein Folding, Edited by B.T. Nall and K.A. Dill. Washington: Amer Soc Adv Sci. 1991; 86-114.
    183. James T, Borgias B, Bianucci AM, Zhou N. Solution Structure Refinement Using Complete Relaxation Matrix Analysis of 2D NOE Experiments: DNA Fragments. NMR and Biomolecular Structure, Edited by I. Bertini, H. Molinari, and N. Niccolai. Weinheim: VCH Verlagsgesellschaft. 1991; 87-111.
    184. Smith V, Kurhanewicz J, James T . Solvent-Suppression Pulses. I. Design Using Optimal Control Theory. J Magn Reson. 1991; 95:41-60.
    185. James T . Relaxation Matrix Analysis of Two-Dimensional Nuclear Overhauser Effect Spectra to Obtain Accurate Biomolecular Structural Constraints and to Assess Structural Quality. Current Opinion in Structural Biology. 1991; 1:1042-1053.
    186. Smith V, Kurhanewicz J, James T . Solvent-Suppression Pulses. II. In Vitro and In Vivo Testing of Optimal Control Theory Pulses. J Magn Reson. 1991; 95:61-70.
    187. James T, Basus VJ. Generation of high-resolution protein structures in solution from multidimensional NMR. Annu Rev Phys Chem. 1991; 42:501-42. PMID: 1747192.
      View in: PubMed
    188. Chang LH, Cohen Y, Weinstein PR, Chileuitt L, James T. Interleaved 1H and 31P spectroscopic imaging for studying regional brain injury. Magn Reson Imaging. 1991; 9(2):223-7. PMID: 2034056.
      View in: PubMed
    189. Gochin M, Zon G, James T. Two-dimensional COSY and two-dimensional NOE spectroscopy of d(AC)4.d(GT)4: extraction of structural constraints. Biochemistry. 1990 Dec 25; 29(51):11161-71. PMID: 2271703.
      View in: PubMed
    190. Gochin M, James T. Solution structure studies of d(AC)4.d(GT)4 via restrained molecular dynamics simulations with NMR constraints derived from two-dimensional NOE and double-quantum-filtered COSY experiments. Biochemistry. 1990 Dec 25; 29(51):11172-80. PMID: 2271704.
      View in: PubMed
    191. Faden AI, Shirane R, Chang LH, James T, Lemke M, Weinstein PR. Opiate-receptor antagonist improves metabolic recovery and limits neurochemical alterations associated with reperfusion after global brain ischemia in rats. J Pharmacol Exp Ther. 1990 Nov; 255(2):451-8. PMID: 2243336.
      View in: PubMed
    192. Lockhart SH, Cohen Y, Yasuda N, Kim F, Litt L, Eger EI, Chang LH, James T. Absence of abundant binding sites for anesthetics in rabbit brain: an in vivo NMR study. Anesthesiology. 1990 Sep; 73(3):455-60. PMID: 2393130.
      View in: PubMed
    193. Fu KK, Wendland MF, Iyer SB, Lam KN, Engeseth H, James T. Correlations between in vivo 31P NMR spectroscopy measurements, tumor size, hypoxic fraction and cell survival after radiotherapy. Int J Radiat Oncol Biol Phys. 1990 Jun; 18(6):1341-50. PMID: 2370183.
      View in: PubMed
    194. Schmitz U, Zon G, James T. Deoxyribose conformation in [d(GTATATAC)]2: evaluation of sugar pucker by simulation of double-quantum-filtered COSY cross-peaks. Biochemistry. 1990 Mar 6; 29(9):2357-68. PMID: 2337605.
      View in: PubMed
    195. Cohen Y, Chang LH, Litt L, Kim F, Severinghaus JW, Weinstein PR, Davis RL, Germano I, James T. Stability of brain intracellular lactate and 31P-metabolite levels at reduced intracellular pH during prolonged hypercapnia in rats. J Cereb Blood Flow Metab. 1990 Mar; 10(2):277-84. PMID: 2303543.
      View in: PubMed
    196. Chang LH, Shirane R, Weinstein PR, James T. Cerebral metabolite dynamics during temporary complete ischemia in rats monitored by time-shared 1H and 31P NMR spectroscopy. Magn Reson Med. 1990 Jan; 13(1):6-13. PMID: 2319935.
      View in: PubMed
    197. James T, Borgias BA, Bianucci AM, Zhou N. Determination of DNA and protein structures in solution via complete relaxation matrix analysis of 2D NOE spectra. Basic Life Sci. 1990; 56:135-54. PMID: 2078169.
      View in: PubMed
    198. Borgias BA, James T . MARDIGRAS –– A Procedure for Matrix Analysis of Relaxation for Discerning Geometry of an Aqueous Structure. J Magn Reson. 1990; 87:475-487.
    199. Borgias BA, Gochin M, Kerkwood DJ, James T . Progress in Nuclear Magnetic Resonance Spectroscopy, Edited by J.W. Emsley, J. Feeney, and L.H. Sutcliffe. Oxford: Pergamon Press. 1990; 83-100.
    200. James T, Borgias BA, Bianucci AM, Zhou N. Determination of DNA and Protein Structure in Solution via Complete Relaxation Matrix Analysis of 2D NOE Spectra. NMR Applications in Biopolymers, Edited by J.W. Finley, S.J. Schmidt, and J.S. Serianni. New York: Plenum Press. 1990; 135-154.
    201. James T, Borgias BA. Determination of DNA and Protein Structures via Complete Relaxation Matrix Analysis of 2D NOE Spectra. . Frontiers of NMR in Molecular Biology, UCLA Symposium on Molecular and Cellular Biology, Vol. 109, Edited by D. Live, I. Armitage, and D. Patel. New York: Alan R. Liss, Inc. 1990; 177-187.
    202. Borgias BA, James T . Biol Magn Reson. 1990; 119-155.
    203. James T . Frontiers of NMR in Molecular Biology, UCLA Symposium on Molecular and Cellular Biology, Vol. 109, Edited by D. Live, I. Armitage, and D. Patel. New York: Alan R. Liss, Inc. 1990; 271-274.
    204. Tzika AA, Vigneron DB, Hricak H, Moseley ME, James T, Kogan BA. P-31 MR spectroscopy in assessing testicular torsion: rat model. Radiology. 1989 Sep; 172(3):753-7. PMID: 2772183.
      View in: PubMed
    205. Vigneron DB, Hricak H, James T, Jajodia PB, Nunes L, Narayan P. Androgen sensitivity of rat prostate carcinoma studied by 31P NMR spectroscopy, 1H MR imaging, and 23Na MR imaging. Magn Reson Med. 1989 Aug; 11(2):152-60. PMID: 2779408.
      View in: PubMed
    206. Narayan P, Vigneron DB, Jajodia P, Anderson CM, Hedgcock MW, Tanagho EA, James T. Transrectal probe for 1H MRI and 31P MR spectroscopy of the prostate gland. Magn Reson Med. 1989 Aug; 11(2):209-20. PMID: 2674600.
      View in: PubMed
    207. Zhou N, James T, Shafer RH. Binding of actinomycin D to [d(ATCGAT)]2: NMR evidence of multiple complexes. Biochemistry. 1989 Jun 13; 28(12):5231-9. PMID: 2548605.
      View in: PubMed
    208. Watters T, Wikman-Coffelt J, Wu S, James T, Sievers R, Parmley WW. Effects of perfusion pressure on energy and work of isolated rat hearts. Hypertension. 1989 May; 13(5):480-8. PMID: 2722227.
      View in: PubMed
    209. Bretan PN, Vigneron DB, McClure RD, Hricak H, Tom RA, Moseley M, Tanagho EA, James T. Assessment of male infertility: correlation between results of semen analysis and phosphorus-31 magnetic resonance spectroscopy. Urology. 1989 Feb; 33(2):116-9. PMID: 2916284.
      View in: PubMed
    210. Borgias BA, James T. Two-dimensional nuclear Overhauser effect: complete relaxation matrix analysis. Methods Enzymol. 1989; 176:169-83. PMID: 2811685.
      View in: PubMed
    211. Oppenheimer NJ, James T . Methods in Enzymology, Nuclear Magnetic Resonance, Part A: Spectral Techniques and Dynamics. Vol 176, 530 pages. New York: Academic Press. 1989.
    212. Oppenheimer NJ, James T . Methods in Enzymology, Nuclear Magnetic Resonance, Part B: Structure and Mechanism, Vol. 177, 507 pages. New York: Academic Press. 1989.
    213. Borgias BA, James T . Methods in Enzymology, NMR Techniques, Part A: Spectral Techniques and Dynamics,Vol 176, Edited by NJ Oppenheimer and TL James. New York: Academic Press. 1989; 169-183.
    214. Cohen Y, Chang L-H, Litt L, James T . Neurotransmission and Cerebrovascular Function, Vol. I, Edited by J Seylaz & T MacKenzie. Amsterdam: Elsevier. 1989; 423-427.
    215. Cohen Y, Chang L-H, Litt L, James T . Spatially Localized COSY Spectra from a Surface Coil Using Phase-Encoding Magnetic Field Gradients. J Magn Reson. 1989; 85:203-208.
    216. Delbarre A, Brown SC, James T, Shafer RH. Spectrophotometric and NMR analysis of the interaction of fluorinated mono- and bifunctional intercalators with DNA, poly(dA-dT), and poly(dG-dC). Biopolymers. 1988 Dec; 27(12):1953-75. PMID: 3240361.
      View in: PubMed
    217. Vigneron DB, Tzika AA, Hricak H, Price DC, Bretan P, Aboseif S, Müller S, James T. Complete and partial ureteral obstruction: evaluation of renal effects with P-31 MR spectroscopy and Tc-DMSA scintigraphy. Radiology. 1988 Sep; 168(3):645-50. PMID: 2841718.
      View in: PubMed
    218. Zhou N, Manogaran S, Zon G, James T. Deoxyribose ring conformation of [d(GGTATACC)]2: an analysis of vicinal proton-proton coupling constants from two-dimensional proton nuclear magnetic resonance. Biochemistry. 1988 Aug 9; 27(16):6013-20. PMID: 2847781.
      View in: PubMed
    219. Wikman-Coffelt J, Wu ST, Watters T, James T, Parmley WW, Mason DT. Biochemical regulation of developed intraventricular systolic pressure. Am Heart J. 1988 Apr; 115(4):876-91. PMID: 2451413.
      View in: PubMed
    220. Camacho SA, Wikman-Coffelt J, Wu ST, Watters TA, Botvinick EH, Sievers R, James T, Jasmin G, Parmley WW. Improvement in myocardial performance without a decrease in high-energy phosphate metabolites after isoproterenol in Syrian cardiomyopathic hamsters. Circulation. 1988 Mar; 77(3):712-9. PMID: 3342496.
      View in: PubMed
    221. Camacho SA, Parmley WW, James T, Abe H, Wu ST, Botvinick EH, Watters TA, Schiller N, Sievers R, Wikman-Coffelt J. Substrate regulation of the nucleotide pool during regional ischaemia and reperfusion in an isolated rat heart preparation: a phosphorus-31 magnetic resonance spectroscopy analysis. Cardiovasc Res. 1988 Mar; 22(3):193-203. PMID: 3167943.
      View in: PubMed
    222. Markiewicz W, Wu SS, Sievers R, Parmley WW, Watters TA, James T, Higgins CB, Wikman-Coffelt J. Beneficial effects of verapamil during metabolic acidosis in isolated perfused rat hearts. Cardiovasc Drugs Ther. 1988 Jan; 1(5):493-502. PMID: 3154678.
      View in: PubMed
    223. Ishige N, Pitts LH, Berry I, Nishimura MC, James T. The effects of hypovolemic hypotension on high-energy phosphate metabolism of traumatized brain in rats. J Neurosurg. 1988 Jan; 68(1):129-36. PMID: 3335898.
      View in: PubMed
    224. Pogliani L, T.L. James TL, Laschi LH, N. Ishige N, Pitts LH. 31P NMR of "In Vivo" Insulted Rat Brain. Physica Medica. 1988; 1:13-21.
    225. Gonzalez-Mendez R, Engeseth H, Gibson AAB, de Olivares J, Litt L, James T . The Modulation Theorem in Tailored Radiofrequency Excitation: Application to a Notch Filter. J Magn Reson. 1988; 78:308-313.
    226. Borgias BA, James T . COMATOSE: A Method for Constrained Refinement of Macromolecular Structure Based on Two-Dimensional Nuclear Overhauser Effect Spectra. J Magn Reson. 1988; 79:493-512.
    227. Shirane R, Chang L-H, Weinstein PR, James T . In Advances in Surgery for Cerebral Stroke. Edited by J. Suzuki. Tokyo: Springer-Verlag. 1988; 633-637.
    228. James T, Borgias BM, Bianucci AM, Jamin N, Pattabiraman N, Suzuki E-I, Zhou N, Zon G. Molecular Structure Determination via Complete Relaxation Matrix Analysis of 2D NOE Spectra and Molecular Mechanics: Application to DNA Fragments. NMR Spectroscopy and Drug Development. 1988; 358-379.
    229. Sessler D, Mills P, Gregory G, Litt L, James T. Effects of bicarbonate on arterial and brain intracellular pH in neonatal rabbits recovering from hypoxic lactic acidosis. J Pediatr. 1987 Dec; 111(6 Pt 1):817-23. PMID: 2824738.
      View in: PubMed
    230. Zhou N, Bianucci AM, Pattabiraman N, James T. Solution structure of [d(GGTATACC)]2: wrinkled D structure of the TATA moiety. Biochemistry. 1987 Dec 1; 26(24):7905-13. PMID: 3427113.
      View in: PubMed
    231. Watters TA, Wendland MF, Parmley WW, James T, Botvinick EH, Wu ST, Sievers R, Wikman-Coffelt J. Factors influencing myocardial response to metabolic acidosis in isolated rat hearts. Am J Physiol. 1987 Nov; 253(5 Pt 2):H1261-70. PMID: 3688265.
      View in: PubMed
    232. Richards TL, Keniry MA, Weinstein PR, Pereira BM, Andrews BT, Murphy EJ, James T. Measurement of lactate accumulation by in vivo proton NMR spectroscopy during global cerebral ischemia in rats. Magn Reson Med. 1987 Oct; 5(4):353-7. PMID: 3683164.
      View in: PubMed
    233. Litt L, González-Méndez R, James T, Sessler DI, Mills P, Chew W, Moseley M, Pereira B, Severinghaus JW, Hamilton WK. An in vivo study of halothane uptake and elimination in the rat brain with fluorine nuclear magnetic resonance spectroscopy. Anesthesiology. 1987 Aug; 67(2):161-8. PMID: 3605742.
      View in: PubMed
    234. Markiewicz W, Wu S, Sievers R, Parmley WW, Higgins CB, James T, Jasmin G, Wikman-Coffelt J. Influence of heart rate on metabolic and hemodynamic parameters in the Syrian hamster cardiomyopathy. Am Heart J. 1987 Aug; 114(2):362-8. PMID: 3604893.
      View in: PubMed
    235. Mills P, Sessler DI, Moseley M, Chew W, Pereira B, James T, Litt L. An in vivo 19F nuclear magnetic resonance study of isoflurane elimination from the rabbit brain. Anesthesiology. 1987 Aug; 67(2):169-73. PMID: 3605743.
      View in: PubMed
    236. Chang LH, Pereira BM, Weinstein PR, Keniry MA, Murphy-Boesch J, Litt L, James T. Comparison of lactate concentration determinations in ischemic and hypoxic rat brains by in vivo and in vitro 1H NMR spectroscopy. Magn Reson Med. 1987 Jun; 4(6):575-81. PMID: 3613957.
      View in: PubMed
    237. Ishige N, Pitts LH, Pogliani L, Hashimoto T, Nishimura MC, Bartkowski HM, James T. Effect of hypoxia on traumatic brain injury in rats: Part 2. Changes in high energy phosphate metabolism. Neurosurgery. 1987 Jun; 20(6):854-8. PMID: 3614564.
      View in: PubMed
    238. Wu S, White R, Wikman-Coffelt J, Sievers R, Wendland M, Garrett J, Higgins CB, James T, Parmley WW. The preventive effect of verapamil on ethanol-induced cardiac depression: phosphorus-31 nuclear magnetic resonance and high-pressure liquid chromatographic studies of hamsters. Circulation. 1987 May; 75(5):1058-64. PMID: 3568306.
      View in: PubMed
    239. Bretan PN, Vigneron DB, Hricak H, McClure RD, Yen TS, Moseley M, Tanagho EA, James T. Assessment of testicular metabolic integrity with P-31 MR spectroscopy. Radiology. 1987 Mar; 162(3):867-71. PMID: 3809506.
      View in: PubMed
    240. Benz C, Hollander C, Keniry M, James T, Mitchell M. Lactic dehydrogenase isozymes, 31P magnetic resonance spectroscopy, and in vitro antimitochondrial tumor toxicity with gossypol and rhodamine-123. J Clin Invest. 1987 Feb; 79(2):517-23. PMID: 3805280; PMCID: PMC424116.
    241. James T, Chang LH, Chew W, Gonzalez-Mendez R, Litt L, Mills P, Moseley M, Pereira B, Sessler DI, Weinstein PR. In situ brain metabolism. Ann N Y Acad Sci. 1987; 508:64-80. PMID: 3439713.
      View in: PubMed
    242. Kass DA, Banville DL, Gooding CA, James T. 31P magnetic resonance spectroscopy of mesenteric ischemia. Magn Reson Med. 1987 Jan; 4(1):83-7. PMID: 3821482.
      View in: PubMed
    243. Chew WM, Moseley ME, Mills PA, Sessler D, González-Méndez R, James T, Litt L. Spin-echo fluorine magnetic resonance imaging at 2 T: in vivo spatial distribution of halothane in the rabbit head. Magn Reson Imaging. 1987; 5(1):51-6. PMID: 3586872.
      View in: PubMed
    244. Bretan PN, Vigneron DB, Hricak H, Collins GM, Price DC, Tanagho EA, James T. Assessment of clinical renal preservation by phosphorus-31 magnetic resonance spectroscopy. J Urol. 1987 Jan; 137(1):146-50. PMID: 3540322.
      View in: PubMed
    245. James T, Chang L-H, W. Chew W, Gonzalez-Mendez R, Litt L, Mills P, Moseley M, Pereira B, Sessler DI, Weinstein PR. In Situ Brain Metabolism. In Physiological NMR Spectroscopy: From Isolated Cells to Man, Edited by S.M. Cohen. Ann. N.Y. Acad. Sci., Vol 508. 1987; 64-80.
    246. James T, Chang L-H, Chew W, Gonzalez-Mendez R, Litt L, Mills P, Moseley M, Pereira B, Sessler DI, Weinstein PR. In Situ Brain Metabolism. Ann NY Acad Sci. 1987; 508:64-80.
    247. Chew WM, Chang L-H, Flamig DP, James T . The Swift Method for In Vivo Localized Excitation (SMILE). J Magn Reson. 1987; 75:523-528.
    248. James T, Chew WM, Giannini DD, Gonzalez-Mendez R, Moseley ME, Pogliani L, Vigneron D . Principles of Magnetic Resonance Spectroscopy. Appl Radiol. 1987; 16:40-52.
    249. Pogliani L, Valensin G, Pitts LH, Ishige N, James T . 31P NMR Results of In Vivo Insulted Rat Brain. A Qualitative Interpretation of the Metabolic Changes. Physica Medica. 1987; 1:35-41.
    250. Murphy-Boesch J, So G, James T . Precision Mapping of the B1 Field Using the Rotating Frame Experiment. J Magn Reson. 1987; 73:293-299.
    251. Chang L-H, Chew WM, Weinstein PR, James T . A Balance-Matched Double-Tuned Probe for In Vivo 1H and 31P NMR. J Magn Reson. 1987; 72:168-172.
    252. Markiewicz W, Wu SS, Parmley WW, Higgins CB, Sievers R, James T, Wikman-Coffelt J, Jasmin G. Evaluation of the Hereditary Syrian Hamster Cardiomyopathy by 31P Nuclear Magnetic Resonance Spectroscopy: Improvement After Acute Verapamil Therapy. Circulation Research. 1987; 59:597-604.
    253. Moseley ME, Chew WM, Brant-Zawadzki M, James T . 1987; 107-113.
    254. James T, Suzuki E-I, N. Pattabiraman N, Zon G. Detailed Structure Determination of DNA Fragments Using Complete Relaxation Matrix Analysis of Two-Dimensional NMR Spectra, Molecular Mechanics Calculations and Computer Graphics. In Biophosphates and Their Analogues. Synthesis, Metabolism, and Activity. Edited by K.S. Bruzik and W.J. Stec. Amsterdam: Elsevier Science, . 1987; 503-514.
    255. Berman E, Lis H, James T. Binding of [1-13C]galactose-enriched hen ovalbumin to Erythrina cristagalli agglutinin as studied by 13C-NMR spectroscopy. Eur J Biochem. 1986 Dec 15; 161(3):589-94. PMID: 3792309.
      View in: PubMed
    256. Bretan PN, Vigneron DB, Hricak H, Juenemann KP, Williams RD, Tanagho EA, James T. Assessment of renal preservation by phosphorus-31 magnetic resonance spectroscopy: in vivo normothermic blood perfusion. J Urol. 1986 Dec; 136(6):1356-9. PMID: 3534322.
      View in: PubMed
    257. Margulis AR, James T. Localized tissue MR spectroscopy. AJR Am J Roentgenol. 1986 Dec; 147(6):1327-8. PMID: 3490773.
      View in: PubMed
    258. Markiewicz W, Wu SS, Parmley WW, Higgins CB, Sievers R, James T, Wikman-Coffelt J, Jasmin G. Evaluation of the hereditary Syrian hamster cardiomyopathy by 31P nuclear magnetic resonance spectroscopy: improvement after acute verapamil therapy. Circ Res. 1986 Dec; 59(6):597-604. PMID: 3815756.
      View in: PubMed
    259. LaPlanche LA, James T, Powell C, Wilson WD, Uznanski B, Stec WJ, Summers MF, Zon G. Phosphorothioate-modified oligodeoxyribonucleotides. III. NMR and UV spectroscopic studies of the Rp-Rp, Sp-Sp, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diastereomeric O-ethyl phosphorothioates. Nucleic Acids Res. 1986 Nov 25; 14(22):9081-93. PMID: 3786144; PMCID: PMC311930.
    260. Suzuki E, Pattabiraman N, Zon G, James T. Solution structure of [d(A-T)5]2 via complete relaxation matrix analysis of two-dimensional nuclear Overhauser effect spectra and molecular mechanics calculations: evidence for a hydration tunnel. Biochemistry. 1986 Nov 4; 25(22):6854-65. PMID: 3801398.
      View in: PubMed
    261. Litt L, González-Méndez R, Weinstein PR, Severinghaus JW, Hamilton WK, Shuleshko J, Murphy-Boesch J, James T. An in vivo 31P NMR study of cerebral hypoxic hypoxia in rats. Magn Reson Med. 1986 Aug; 3(4):619-25. PMID: 3747822.
      View in: PubMed
    262. Litt L, González-Méndez R, Severinghaus JW, Hamilton WK, Rampil IJ, Shuleshko J, Murphy-Boesch J, James T. Cerebral intracellular ADP concentrations during hypercarbia: an in vivo 31P nuclear magnetic resonance study in rats. J Cereb Blood Flow Metab. 1986 Jun; 6(3):389-92. PMID: 3711164.
      View in: PubMed
    263. Keniry M, Benz C, Shafer RH, James T. Noninvasive spectroscopic analysis of fluoropyrimidine metabolism in cultured tumor cells. Cancer Res. 1986 Apr; 46(4 Pt 1):1754-8. PMID: 3456267.
      View in: PubMed
    264. Bretan PN, Vigneron DB, James T, Williams RD, Hricak H, Juenemann KP, Yen TS, Tanagho EA. Assessment of renal viability by phosphorus-31 magnetic resonance spectroscopy. J Urol. 1986 Apr; 135(4):866-71. PMID: 3514965.
      View in: PubMed
    265. Schmidt HC, Gooding CA, James T. In vivo 31P-MR spectroscopy of the liver in the infant rabbit to study the effect of hypoxia on the phosphorus metabolites and intracellular pH. Invest Radiol. 1986 Feb; 21(2):156-61. PMID: 3957589.
      View in: PubMed
    266. Koretsky AP, Wang S, Klein MP, James T, Weiner MW. 31P NMR saturation transfer measurements of phosphorus exchange reactions in rat heart and kidney in situ. Biochemistry. 1986 Jan 14; 25(1):77-84. PMID: 3954995.
      View in: PubMed
    267. Schmidt HC, Gooding CA, James TL, Gonzalez-Mendez R, James T. Comparison of in vivo 31P-MR spectra of the brain, liver, and kidney of adult and infant animals. Pediatr Radiol. 1986; 16(2):144-9. PMID: 3951898.
      View in: PubMed
    268. James T . Technical Obstacles Hinder Spread of MR Spectroscopy. Diagnostic Imaging. 1986; 8:218-221.
    269. James T, Chew WM, Giannini DD, Gonzalez-Mendez R, Moseley ME, Pogliani L, Vigneron D . Magnetic Resonance Spectroscopy: Principles and Potential Application. Applied Radiol. 1986; 16:40-52.
    270. James T, Broido MS, Jamin N, Young GB, Zon G. Structure and Dynamics via Two-dimensional NMR. Illustrations with DNA Fragments. In Advanced Magnetic Resonance Techniques in Systems of High Molecular Complexity. Edited by N. Nicolai and G. Valensin. Boston: Birkhauser. 1986; 81-108.
    271. James T, Suzuki E-I, Pattabiraman N, Zon G. 2D NOE Full Relaxation Matrix Analysis and Molecular Mechanics Calculations for Structure Determination in Solution: DNA Fragments. Bull Magn Reson. 1986; 8:152-156.
    272. Margulis AR, James T . Localized Tissue MR Spectroscopy. Am J Roentgenol. 1986; 147:1327-1328.
    273. Chew WM, Moseley ME, Nishimura MC, Hashimoto T, Pitts LH, James T. A novel double-surface coil approach to phosphorus-31 spectroscopy: a study of hemispheric brain injury in the rat. Magn Reson Med. 1985 Dec; 2(6):567-75. PMID: 3880098.
      View in: PubMed
    274. Litt L, González-Méndez R, Severinghaus JW, Hamilton WK, Shuleshko J, Murphy-Boesch J, James T. Cerebral intracellular changes during supercarbia: an in vivo 31P nuclear magnetic resonance study in rats. J Cereb Blood Flow Metab. 1985 Dec; 5(4):537-44. PMID: 4055925.
      View in: PubMed
    275. Koretsky AP, Basus VJ, James T, Klein MP, Weiner MW. Detection of exchange reactions involving small metabolite pools using NMR magnetization transfer techniques: relevance to subcellular compartmentation of creatine kinase. Magn Reson Med. 1985 Dec; 2(6):586-94. PMID: 3880100.
      View in: PubMed
    276. González-Méndez R, McNeill A, Gregory GA, Wall SD, Gooding CA, Litt L, James T. Effects of hypoxic hypoxia on cerebral phosphate metabolites and pH in the anesthetized infant rabbit. J Cereb Blood Flow Metab. 1985 Dec; 5(4):512-6. PMID: 4055924.
      View in: PubMed
    277. Berman E, Brown SC, James T, Shafer RH. NMR studies of chromomycin A3 interaction with DNA. Biochemistry. 1985 Nov 19; 24(24):6887-93. PMID: 2416346.
      View in: PubMed
    278. Jamin N, James T, Zon G. Two-dimensional nuclear Overhauser enhancement investigation of the solution structure and dynamics of the DNA octamer [d(GGTATACC)]2. Eur J Biochem. 1985 Oct 1; 152(1):157-66. PMID: 4043076.
      View in: PubMed
    279. Brody AS, Sorette MP, Gooding CA, Listerud J, Clark MR, Mentzer WC, Brasch RC, James T. AUR memorial Award. Induced alignment of flowing sickle erythrocytes in a magnetic field. A preliminary report. Invest Radiol. 1985 Sep; 20(6):560-6. PMID: 2933361.
      View in: PubMed
    280. Shine NR, Bubienko E, James T. Interactions of diastereomeric tripeptides of lysyl-5-fluorotryptophyllysine with DNA. 2. Optical, 19F NMR, and strand cleavage studies of apurinic DNA complexes. Biochemistry. 1985 Jul 30; 24(16):4341-5. PMID: 4052401.
      View in: PubMed
    281. Shine NR, James T. Interactions of diastereomeric tripeptides of lysyl-5-fluorotryptophyllysine with DNA. 1. Optical and 19F NMR studies of native DNA complexes. Biochemistry. 1985 Jul 30; 24(16):4333-41. PMID: 4052400.
      View in: PubMed
    282. Broido MS, James T, Zon G, Keepers JW. Investigation of the solution structure of a DNA octamer [d(GGAATTCC)]2 using two-dimensional nuclear Overhauser enhancement spectroscopy. Eur J Biochem. 1985 Jul 1; 150(1):117-28. PMID: 2990923.
      View in: PubMed
    283. Wolff S, James T, Young GB, Margulis AR, Bodycote J, Afzal V. Magnetic resonance imaging: absence of in vitro cytogenetic damage. Radiology. 1985 Apr; 155(1):163-5. PMID: 4038809.
      View in: PubMed
    284. Moseley ME, Chew WM, Nishimura MC, Richards TL, Murphy-Boesch J, Young GB, Marschner TM, Pitts LH, James T. In vivo sodium-23 magnetic resonance surface coil imaging: observing experimental cerebral ischemia in the rat. Magn Reson Imaging. 1985; 3(4):383-7. PMID: 4088012.
      View in: PubMed
    285. James T. Phosphorus-31 NMR as a probe for phosphoproteins. CRC Crit Rev Biochem. 1985; 18(1):1-30. PMID: 3160538.
      View in: PubMed
    286. Stark DD, Moseley ME, Bacon BR, Moss AA, Goldberg HI, Bass NM, James T. Magnetic resonance imaging and spectroscopy of hepatic iron overload. Radiology. 1985 Jan; 154(1):137-42. PMID: 3964933.
      View in: PubMed
    287. James T, Phosphorus-31 NMR as a Probe for Phosphoproteins. In CRC Critical Reviews in Biochemistry, Vol. 18, Edited by G.D. Fasman. Boca Raton: CRC Press. 1985; 1-30.
    288. James T, In Vivo Nuclear Magnetic Resonance Spectroscopy. Article in Workshop on Advances in NASA-Relevant, Minimally Invasive Instrumentation, April 25-27, 1984, Asilomar, California. Pasadena: NASA Jet Propulsion Laboratory. 1985; 33-52.
    289. James T, Gonzalez-Mendez R, Litt L. Magnetic Resonance Spectroscopy: Principles and Potential Application in Medicine. Chapter in Contemporary Imaging. Edited by H.I. Goldberg, C.B. Higgins, and E.J. Ring. San Francisco: Radiology Research and Education Foundation. 1985; 141-148.
    290. James T, Young GB, Broido MS, Keepers JW, Jamin N, Zon G. Quantitative Internuclear Distances via 2D NMR Spectra: A Test Case and DNA Octamer Duplex. In Proceedings of the International Symposium on Biomolecular Structure and Interactions. Edited by V. Sasisekharan and K.R.K. Easwaran. 1985; 553-562.
    291. Gonzalez-Mendez R, Moseley ME, Murphy-Boesch J, Chew WM, Litt L, James T . Selective Inversion with Surface Coils: Use of Depth Pulses for the Inversion Transfer Experiment In Vivo. J Magn Reson. 1985; 65:516-521.
    292. Keepers JW, Schmidt P, James T, Kollman PA. Molecular-mechanical studies of the mismatched base analogs of d(CGCGAATTCGCG)2:d(CGTGAATTCGCG)2, d(CGAGAATTCGCG)2, d(CGCGAATTCACG)2, d(CGCGAATTCTCG)2, and d(CGCAGAATTCGCG).d(CGCGAATTCGCG). Biopolymers. 1984 Dec; 23(12):2901-29. PMID: 6525406.
      View in: PubMed
    293. Keepers J, Kollman PA, James T. Molecular mechanical studies of base-pair opening in d(CGCGC):d(GCGCG), dG5 . dC5, d(TATAT):d(ATATA), and dA5 . dT5 in the B and Z forms of DNA. Biopolymers. 1984 Nov; 23(11 Pt 2):2499-511. PMID: 6518264.
      View in: PubMed
    294. Sherry AD, Keepers J, James T, Teherani J. Methyl motions in 13C-methylated concanavalin as studied by 13C magnetic resonance relaxation techniques. Biochemistry. 1984 Jul 3; 23(14):3181-5. PMID: 6432038.
      View in: PubMed
    295. Gochin M, James T, Shafer RH. In vivo 19F-NMR of 5-fluorouracil incorporation into RNA and metabolites in Escherichia coli cells. Biochim Biophys Acta. 1984 May 22; 804(1):118-24. PMID: 6202324.
      View in: PubMed
    296. Broido MS, Zon G, James T. Complete assignment of the non-exchangeable proton nmr resonances of [d-(GGAATTCC)]2 using two-dimensional nuclear overhauser effect spectra. Biochem Biophys Res Commun. 1984 Mar 15; 119(2):663-70. PMID: 6712651.
      View in: PubMed
    297. Moseley ME, Nishimura MC, Pitts LH, Bartkowski HM, James T. Proton nuclear magnetic resonance spectroscopy of normal and edematous brain tissue in vitro: changes in relaxation during tissue storage. Magn Reson Imaging. 1984; 2(3):205-9. PMID: 6530927.
      View in: PubMed
    298. James T, Margulis AR (Editors). Biomedical Magnetic Resonance, San Francisco: Radiology Research and Education Foundation. 1984; 1-462.
    299. Moseley ME, Nishimura MC, Pitts LH, Bartkowski HM, James T . Proton Nuclear Magnetic Resonance Spectroscopy of Normal and Edematous Brain Tissue In Vitro: Changes in Relaxation during Tissue Storage. Magn Reson Imaging. 1984; 2:205-209.
    300. Moseley ME, Chew WM, James T . 1984; 267-271.
    301. James T, Basic Nuclear Magnetic Resonance Principles. Chapter 2 in Biomedical Magnetic Resonance. Edited by T.L. James and A.R. Margulis. San Francisco: Radiology Research and Education Foundation. 1984; 7-22.
    302. James T, Margulis AR. Historical Development of Biomedical Magnetic Resonance. Chapter 1 in Biomedical Magnetic Resonance, Edited by T.L. James and A.R. Margulis. San Francisco: Radiology Research and Education Foundation. 1984; 1-6.
    303. James T, In Vivo Nuclear Magnetic Resonance Spectroscopy. Chapter in NMR, CT, and Interventional Radiology. Edited by A.A. Moss, E.J. Ring, and C.B. Higgins. San Francisco: Radiology Education and Research Foundation. 1984; 235-244.
    304. James T, Edited by D. Gorenstein. New York: Academic Press. 1984; 349-400.
    305. Young GB, James T . Determination of Molecular Structure in Solution via Two-Dimensional Nuclear Overhauser Effect Experiments: Proflavine as a Rigid Molecule Test Case. J Amer Chem Soc. 1984; 106:7986-7988.
    306. Gonzales-Mendez R, Litt L, Koretsky AP, von Colditz J, Weiner MW, James T . Comparison of 31P NMR Spectra of In Vivo Rat Brain Using Convolution Difference and Saturation with a Surface Coil. Source of the Broad Component in the Brain Spectrum. J Magn Reson. 1984; 57:526-533.
    307. Keepers JW, James T . A Theoretical Study of Distance Determinations from NMR. Two-Dimensional Nuclear Overhauser Effect Spectra. J Magn Reson. 1984; 57:404-426.
    308. Sievers R, Parmley WW, James T, Wikman-Coffelt J. Energy levels at systole vs. diastole in normal hamster hearts vs. myopathic hamster hearts. Circ Res. 1983 Dec; 53(6):759-66. PMID: 6640862.
      View in: PubMed
    309. Koretsky AP, Wang S, Murphy-Boesch J, Klein MP, James T, Weiner MW. 31P NMR spectroscopy of rat organs, in situ, using chronically implanted radiofrequency coils. Proc Natl Acad Sci U S A. 1983 Dec; 80(24):7491-5. PMID: 6584867; PMCID: PMC389977.
    310. Delbarre A, Shafer RH, James T. 19F-NMR study of DNA bis-intercalation. Biopolymers. 1983 Dec; 22(12):2497-500. PMID: 6667327.
      View in: PubMed
    311. Bendel P, Murphy-Boesch J, James T. Deuterium NMR in the solid-state and in solution of the molecular motion of the bases in poly(I) and poly(I) . poly(C). Biochim Biophys Acta. 1983 Sep 13; 759(3):205-13. PMID: 6882799.
      View in: PubMed
    312. Düzgünes N, Wilschut J, Hong K, Fraley R, Perry C, Friend DS, James T, Papahadjopoulos D. Physicochemical characterization of large unilamellar phospholipid vesicles prepared by reverse-phase evaporation. Biochim Biophys Acta. 1983 Jul 13; 732(1):289-99. PMID: 6688185.
      View in: PubMed
    313. Bendel P, James T. Structural and dynamic differences between supercoiled and linear DNA from proton NMR. Proc Natl Acad Sci U S A. 1983 Jun; 80(11):3284-6. PMID: 6574485; PMCID: PMC394025.
    314. Berman E, James T. 13C-n.m.r.-spectral study of galactosyltransferase specificity with regard to the carbohydrate side-chain of native ovalbumin. Carbohydr Res. 1983 Feb 16; 113(1):141-50. PMID: 6404553.
      View in: PubMed
    315. James T, Schmidt PG. NMR of Nucleic Acids. Magn Reson Rev. 1983; 8:139-163.
    316. Koretsky AP, Wang S, Murphy-Boesch J, Klein MP, James T, Weiner MW. 13P NMR Spectroscopy of Rat Organs, In Situ, Using Chronically Implanted Radiofrequency Coils. Proc Nat Acad Sci. 1983; 80:7491-7495.
    317. James T . Conformational Flexibility in Nucleic Acids Investigated by NMR Relaxation. Bull Magn Reson. 1983; 4:119-159.
    318. James T, Bendel P, Keepers JW, Taylor JE . The Dynamic Structure of Nucleic Acids. Bull Magn Reson. 1983; 5:165-167.
    319. James T, C.B. Higgins, L. Kaufman, and L.E. Crooks. San Francisco: Radiology Research and Education Foundation. 1983; 41-51.
    320. James T, Bendel P, James JL, Keepers JW, Kollman PA, Lapidot A, Murphy-Boesch J, Taylor JE. Conformational Flexibility of Nucleic Acids. Chapter in Nucleic Acids: The Vectors of Life,. Edited by B. Pullman and J. Jortner. D. Reidel. 1983; 155-167.
    321. Koretsky A, Straus W, Basus V, Murphy J, Bendel P, James T, Weiner M. Feasibility of 31P NMR to Study Metabolic Effects of Renal Ischemia In Vivo. Proceedings of the Eighth International Congress on Nephrology, Satellite Symposium on Acute Renal Failure, Edited by H.E. Eliahu. New York: Saunders. 1983; 42-48.
    322. Bolton PH, Clawson G, Basus VJ, James T. Comparison of ribonucleic acid-protein interactions in messenger ribonucleoproteins, ribosomes, MS2 virus, and Q beta virus examined via phosphorus-31 nuclear magnetic resonance relaxation. Biochemistry. 1982 Nov 23; 21(24):6073-81. PMID: 7150544.
      View in: PubMed
    323. Taylor A, Sawan S, James T. Structural aspects of the inhibitor complex formed by N-(leucyl)-o-aminobenzenesulfonate and manganese with Zn2+-Mn2+ leucine aminopeptidase (EC 3.4.11.1). Studies by NMR. J Biol Chem. 1982 Oct 10; 257(19):11571-6. PMID: 7118898.
      View in: PubMed
    324. Keepers JW, Kollman PA, Weiner PK, James T. Molecular mechanical studies of DNA flexibility: coupled backbone torsion angles and base-pair openings. Proc Natl Acad Sci U S A. 1982 Sep; 79(18):5537-41. PMID: 6957879; PMCID: PMC346939.
    325. Mirau PA, Shafer RH, James T, Bolton PH. Fluoroquinacrine binding to nucleic acids: investigation of the 19F-NMR, optical, and fluorescence properties in the presence of DNA, poly(A), and tRNA. Biopolymers. 1982 May; 21(5):909-21. PMID: 7082769.
      View in: PubMed
    326. Goux WJ, Perry C, James T. An NMR study of 13C-enriched galactose attached to the single carbohydrate chain of hen ovalbumin. Motions of the carbohydrates of glycoproteins. J Biol Chem. 1982 Feb 25; 257(4):1829-35. PMID: 7056747.
      View in: PubMed
    327. Mirau PA, Shafer RH, James T. Binding of 5-fluorotryptamine to polynucleotides as a model for protein-nucleic acid interactions: fluorine-19 nuclear magnetic resonance, absorption, and fluorescence studies. Biochemistry. 1982 Feb 16; 21(4):615-20. PMID: 7074027.
      View in: PubMed
    328. Edmondson DE, James T, Edited by V. Massey and C.H. Williams. Amsterdam: Elsevier North Holland, Inc. . 1982; 111-118.
    329. Bendel P, James T . Transverse Relaxation of 31P in 5'-AMP. J Magn Reson. 1982; 48:76-85.
    330. Bendel P, Laub O, James T . Molecular Motions of Supercoiled and Circular-DNA. A Phosphorus-31 Nuclear Magnetic Resonance Study. J Am Chem Soc. 1982; 104:6748-6753.
    331. Keepers JW, James T . Models for DNA Backbone Motions: An Interpretation of NMR Relaxation Experiments. J Amer Chem Soc. 1982; 104:929-939.
    332. Bolton PH, Mirau PA, Shafer RH, James T. Interaction of the antimalarial drug fluoroquine with DNA, tRNA, and poly(A): 19F-NMR chemical-shift and relaxation, optical absorption, and fluorescence studies. Biopolymers. 1981 Mar; 20(3):435-49. PMID: 7011433.
      View in: PubMed
    333. James T, Edmondson DE, Husain M. Glucose oxidase contains a disubstituted phosphorus residue. Phosphorus-31 nuclear magnetic resonance studies of the flavin and nonflavin phosphate residues. Biochemistry. 1981 Feb 3; 20(3):617-21. PMID: 7213598.
      View in: PubMed
    334. Nuss ME, James T, Apple MA, Kollman PA. An NMR study of the interaction of daunomycin with dinucleotides and dinucleoside phosphates. Biochim Biophys Acta. 1980 Aug 26; 609(1):136-47. PMID: 7407180.
      View in: PubMed
    335. Bolton PH, James T. Conformational mobility of deoxyribonucleic acid, transfer ribonucleic acid, and poly(adenylic acid) as monitored by carbon-13 nuclear magnetic resonance relaxation. Biochemistry. 1980 Apr 1; 19(7):1388-92. PMID: 7387998.
      View in: PubMed
    336. Davies GK, Tolhurst-Cleaver CL, James T. CNS depression from intrathecal morphine. Anesthesiology. 1980 Mar; 52(3):280. PMID: 6892756.
      View in: PubMed
    337. James T . Internal Motions in Proteins Examined by 13C NMR Rotating Frame Spin-Lattice Relaxation: Chymotrypsinogen. J Magn Reson. 1980; 39:141-153.
    338. Bolton PH, James T . Fast and Slow Conformational Fluctuations of RNA and DNA. Subnanosecond Internal Motion Correlation Times Determined by 31P NMR. J Am Chem Soc. 1980; 102(1):25-31.
    339. Harkey MR, Settle WL, James T, Trevor AJ. Spectral studies on the interaction of dichloromethane with hemoglobin. Mol Pharmacol. 1979 Nov; 16(3):1065-74. PMID: 530249.
      View in: PubMed
    340. Edmondson DE, James T. Covalently bound non-coenzyme phosphorus residues in flavoproteins: 31P nuclear magnetic resonance studies of Azotobacter flavodoxin. Proc Natl Acad Sci U S A. 1979 Aug; 76(8):3786-9. PMID: 291038; PMCID: PMC383919.
    341. James T, Matthews R, Matson GB. Hemoglobin aggregation in oxygenated sickle cells studies by carbon-13 rotating frame spin-lattice relaxation in the presence of an off-resonance radiofrequency field. Biopolymers. 1979 Jul; 18(7):1763-8. PMID: 540130.
      View in: PubMed
    342. James T, Matson GB. Rotating Frame Spin-Lattice Relaxation in the Presence of an Off-Resonance Radiofrequency Field. Scalar Relaxation of 31P in PBr3. J Magn Reson. 1979; 33:345-353.
    343. James T, Sawan SP. Unfolding of Ribonuclease A by Guanidinium Chloride. Protein Internal Motions Studied by Nuclear Magnetic Resonance Spin-Lattice Relaxation in an Off-Resonance Rotating Frame. J Am Chem Soc. 1979; 101(23):7050-7055.
    344. Sawan SP, James T, Gruenke LD, Craig JC. Proton NMR Assignments for Cholesterol. Use of Deuterium NMR as an Assignment Aid. J Magn Reson. 1979; 35:409-414.
    345. James T . Chapter 14 in NMR and Biochemistry. A Symposium Honoring Mildred Cohn. Edited by SJ Opella and P Lu. 1979; 211-223.
    346. Bolton PH, James T . Line Narrowing Induced by Selective Population Transfer. J Magn Reson. 1979; 36:443-446.
    347. Bolton PH, James T . Molecular Motions in RNA and DNA Investigated by Phosphorus-31 and Carbon-13 NMR Relaxation. J Phys Chem. 1979; 83(26):3359-3366.
    348. Fisher RW, James T. Lateral diffusion of the phospholipid molecule in dipalmitoylphosphatidylcholine bilayers. An investigation using nuclear spin--lattice relaxation in the rotating frame. Biochemistry. 1978 Apr 4; 17(7):1177-83. PMID: 580765.
      View in: PubMed
    349. Matthews RM, James T. Effect of dichloromethane on sickle cells. An in vitro water proton magnetic resonance relaxation study. Biochem Biophys Res Commun. 1978 Feb 28; 80(4):879-85. PMID: 637872.
      View in: PubMed
    350. James T, Matson GB, Kuntz ID. Protein Rotational Correlation Times Determined in Aqueous Solution by Carbon-13 Rotating Frame Spin-Lattice Relaxation in the Presence of an Off-Resonance Radiofrequency Field. J Am Chem Soc. 1978; 11(100): 3590-3594.
    351. Sawan SP, James T . Use of a Plastic Tube Insert for NMR Experiments Entailing Hazardous Samples. J Magn Reson. 1978; 32:173-174.
    352. Zipp A, Kuntz ID, James T. Hemoglobin-water interactions in normal and sickle erythrocytes by proton magnetic resonance T1p measurements. Arch Biochem Biophys. 1977 Jan 30; 178(2):435-41. PMID: 836043.
      View in: PubMed
    353. James T, Matson GB, Kuntz ID, Fisher RW, Buttlaire DH . Rotating Frame Spin-Lattice Relaxation in the Presence of an Off-Resonance Radiofrequency Field. Investigation of Intermediate Molecular Motion. J Magn Reson. 1977; 28:417-426.
    354. James T. Binding of adenosine 5'-diphosphate to creatine kinase. An investigation using intermolecular nuclear Overhauser effect measurements. Biochemistry. 1976 Oct 19; 15(21):4724-30. PMID: 974086.
      View in: PubMed
    355. James T, Pogolotti AL, Ivanetich KM, Wataya Y, Lam SS, Santi DV. Thymidylate synthetase: fluorine-19 nmr characterization of the active site peptide covalently bound to 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate. Biochem Biophys Res Commun. 1976 Sep 20; 72(2):404-10. PMID: 825116.
      View in: PubMed
    356. Zipp A, James T, Kuntz ID, Shohet SB. Water proton magnetic resonance studies of normal and sickle erythrocytes. Temperature and volume dependence. Biochim Biophys Acta. 1976 Apr 23; 428(2):291-303. PMID: 1276160.
      View in: PubMed
    357. Zipp A, Kuntz ID, James T . An Investigation of "Bound" Water in Frozen Erythrocytes by Proton Magnetic Resonance Spin-Lattice, Spin-Spin, and Rotating Frame Spin-Lattice Relaxation Time Measurements. J Magn Reson. 1976; 24:411-424.
    358. Santi DV, Pogolotti AL, James T, Wataya Y, Ivanetich KM, Lam SSM. Thymidylate Synthetase: Interaction with 5-Fluoro and 5-Trifluoromethyl-2'-Deoxyuridylic Acid. ACS Symposium Series. Biochemistry Involving Carbon-Fluorine Bonds. 1976; 57-76.
    359. Kuntz ID, Zipp A, James T, pp. 499-503. ACS Symposium Series, Number 34. Edited by H.A. Resing and C.G. Wade. American Chemical Society, 1976. ACS Symposium Series. Magnetic Resonance in Colloid and Interface Science. 1976; 499-503.
    360. Swett C. Outpatient phenothiazine use and bone marrow depression. A report from the drug epidemiology unit and the Boston collaborative drug surveillance program. Arch Gen Psychiatry. 1975 Nov; 32(11):1416-8. PMID: 978.
      View in: PubMed
    361. Stein JM. The effect of adrenaline and of alpha- and beta-adrenergic blocking agents on ATP concentration and on incorporation of 32Pi into ATP in rat fat cells. Biochem Pharmacol. 1975 Sep 15; 24(18):1659-62. PMID: 12.
      View in: PubMed
    362. Järvisalo J, Saris NE. Action of propranolol on mitochondrial functions--effects on energized ion fluxes in the presence of valinomycin. Biochem Pharmacol. 1975 Sep 15; 24(18):1701-5. PMID: 13.
      View in: PubMed
    363. Makar AB, McMartin KE, Palese M, Tephly TR. Formate assay in body fluids: application in methanol poisoning. Biochem Med. 1975 Jun; 13(2):117-26. PMID: 1.
      View in: PubMed
    364. James T . Nuclear Magnetic Resonance in Biochemistry. 1975; 413 pages.
    365. James T, Cohn M. Structural aspects of manganese-pyruvate kinase substrate and inhibitor complexes deduced from proton magnetic relaxation rates of pyruvate and a phosphoenolpyruvate analog. J Biol Chem. 1974 Jun 10; 249(11):3519-26. PMID: 4831226.
      View in: PubMed
    366. Ostroy F, James T, Noggle JH, Sarrif A, Hokin LE. Studies on the characterization of the sodium-potassium transport adenosinetriphosphatase. Nuclear magnetic resonance studies of 23Na binding to the purified and partially purified enzyme. Arch Biochem Biophys. 1974 Jun; 162(2):421-5. PMID: 4276201.
      View in: PubMed
    367. James T, Cohn M. The role of the lysyl residue at the active site of creatine kinase. Nuclear Overhauser effect studies. J Biol Chem. 1974 Apr 25; 249(8):2599-604. PMID: 4856652.
      View in: PubMed
    368. James T, Ludwig ML, Cohn M. Dependence of the proton magnetic resonance spectra on the oxidation state of flavodoxin from Clostridium MP and from Peptostreptococcus elsdenii. Proc Natl Acad Sci U S A. 1973 Dec; 70(12):3292-5. PMID: 4519623; PMCID: PMC427222.
    369. James T, Reuben J, Cohn M. Nuclear magnetic resonance study of the binding of phosphoenolpyruvate and phosphoenol-alpha-ketobutyrate to manganese pyruvate kinase. Temperature, frequency,and monovalent cation dependence of water proton nuclear magnetic resonance relaxation rates. J Biol Chem. 1973 Sep 25; 248(18):6443-9. PMID: 4730326.
      View in: PubMed
    370. James T, McDonald GG. Measurement of the Self-Diffusion Coefficient of Each Component in a Complex System Using Pulsed-Gradient Fourier Transform NMR. J Magn Reson. 1973; 11:58-61.
    371. James T, Gillen KT. Nuclear magnetic resonance relaxation time and self-diffusion constant of water in hen egg white and yolk. Biochim Biophys Acta. 1972 Nov 24; 286(1):10-5. PMID: 4676548.
      View in: PubMed
    372. James T, Noggle JH. 23 Na NMR studies of sodium ion interactions: phosphatidyl serine, phosphoserine, and phosphoethanolamine. Anal Biochem. 1972 Sep; 49(1):208-17. PMID: 5081100.
      View in: PubMed
    373. Mild KH, James T, Gillen KT. Nuclear magnetic resonance relaxation time and self-diffusion coefficient measurements of water in frog ovarian eggs (Rana pipiens). J Cell Physiol. 1972 Aug; 80(1):155-8. PMID: 4538489.
      View in: PubMed
    374. James T, Noggle JH . 23Na NMR Studies of Sodium Ion Interactions: Cysteine, Aspartic Acid, and Citric Acid. Bioinorg Chem. 1972; 2:69-74.
    375. Blaedel WJ, Brower LE, James T, Noggle JH. Pulsed Nuclear Magnetic Resonance Measurement of Relaxation Times in Ion-Exchange Resins. Anal Chem. 1972; 44(6):982-985.
    376. James T . Photoelectron Spectroscopy. J Chem Educ. 1971; 48(11):712-718.
    377. James T, Noggle JH. 23Na nuclear magnetic resonance relaxation studies of sodium ion interaction with soluble RNA. Proc Natl Acad Sci U S A. 1969 Mar; 62(3):644-9. PMID: 5256995; PMCID: PMC223645.
    378. James T, Noggle JH. Sodium-23 Nuclear Magnetic Resonance Studies of Sodium Aminocarboxylic Acid Complexes. J Am Chem Soc. 1969; 91(13):3424-2428.
    379. James T, Kula RJ. A Comparison of the Proton Affinities of Neutral Oxygen and Sulfur in Chelating Ligands. J Phys Chem. 1969; 73(3):634-640.
    380. James T . Nuclear Magnetic Resonance Studies of Sodium Aminocarboxylic Acid Complexes. PhD Dissertation, University of Wisconsin, Madison. 1969.
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