Thomas James, PhD

Title(s)Professor, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address600 16th St
San Francisco CA 94158
Phone--
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    Other Positions
    Title(s)Interim Director, Molecular Design Institute


    Collapse Biography 
    Collapse Awards and Honors
    University of New Mexico, Albuquerque1962  - 1965University Roll of Distinction
    University of New Mexico, Albuquerque1962  - 1965University Honor Roll
    University of New Mexico, Albuquerque1964Kappa Mu Epsilon (Mathematics Honorary)
    Bundesrepublik Deutschlan1964German Award
    University of New Mexico, Albuquerque1964Phi Kappa Phi (Scholastic Honorary)
    University of New Mexico, Albuquerque1965Phi Beta Kappa (Scholastic Honorary)

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Development and Application of In-Cell NMR Techniques
    NIH R21GM066039Aug 1, 2002 - Jul 31, 2005
    Role: Principal Investigator
    ACQUISITION OF AN 800 MHZ NMR SPECTROMETER
    NIH S10RR015748Mar 15, 2001 - Sep 14, 2003
    Role: Principal Investigator
    RNA STRUCTURE IN AGILE LOCI OF RIBOSOME AND RETROVIRUSES
    NIH R03TW001465Feb 9, 2001 - Jan 31, 2005
    Role: Principal Investigator
    THERMODYNAMICS OF PROTEIN-DNA &LIGAND-DNA COMPLEXES
    NIH R03TW001234Feb 1, 2000 - Jan 31, 2004
    Role: Principal Investigator
    Three-Dimensional HIV RNA Genome Targeted Drug Leads
    NIH R01AI046967Jan 1, 2000 - Aug 31, 2012
    Role: Principal Investigator
    TARGETING 4.5S RNA ANTIMICROBIAL DRUG DISCOVERY
    NIH R41AI044515Sep 30, 1999 - Sep 29, 2000
    Role: Principal Investigator
    PURCHASE OF Q TOF MASS SPECTROMETER
    NIH S10RR012961May 15, 1998 - May 14, 1999
    Role: Principal Investigator
    ACQUISITION OF A 500 MHZ NMR SPECTROMETER CONSOLE
    NIH S10RR010490Jun 1, 1996 - May 31, 1997
    Role: Principal Investigator
    SLIPPED LOOP STRUCTURE--A NOVEL POLYNUCLEOTIDE FOLDING
    NIH R03TW000438Jul 1, 1994 - Jun 30, 1998
    Role: Principal Investigator
    ACQUISITION OF A 600 MHZ NMR SPECTROMETER
    NIH S10RR007168May 19, 1992 - Sep 30, 1993
    Role: Principal Investigator
    PROTEIN STRUCTURE VIA ANALYSIS OF 2D NMR SPECTRA
    NIH R01GM041639Jan 1, 1991 - Dec 31, 1994
    Role: Principal Investigator
    High Performance Computing for Biomedical Research
    NIH P41RR006009Sep 1, 1990 - Jul 31, 2013
    Role: Co-Investigator
    OMEGA 500 UPGRADE WITH ARRAY PROCESSOR
    NIH S10RR005608Mar 5, 1990 - Mar 4, 1991
    Role: Principal Investigator
    SELF-SHIELDED GRADIENT COILS FOR IN VIVO NMR INSTRUMENT
    NIH S10RR004821Jun 14, 1989 - Jun 13, 1990
    Role: Principal Investigator
    SOLUTION STRUCTURE AND DYNAMICS OF NUCLEIC ACIDS
    NIH R01GM039247Feb 1, 1988 - Jun 30, 2002
    Role: Principal Investigator
    CONSOLE FOR IN VIVO MAGNETIC RESONANCE INSTRUMENT
    NIH S10RR003841Feb 1, 1988 - Jan 31, 1989
    Role: Principal Investigator
    HIGH-FIELD 500MHZ NMR SPECTROMETER
    NIH S10RR003479Jan 15, 1987 - Jan 14, 1988
    Role: Principal Investigator
    IN VIVO NMR SPECTROMETER/IMAGER
    NIH S10RR002433Dec 1, 1984 - Nov 30, 1985
    Role: Principal Investigator
    NATIONAL STABLE ISOTOPE RESOURCE AT LOS ALAMOS
    NIH P41RR002231Dec 1, 1983 - Jun 30, 2005
    Role: Co-Investigator
    Pharmaceutical Sciences and Pharmacogenomics
    NIH T32GM007175Jul 1, 1982 - Jun 30, 2022
    Role: Co-Principal Investigator
    Theoretical Studies of Drug/Nucleic Acid Interactions
    NIH R01CA025644Jan 1, 1980 - Jul 31, 2003
    Role: Principal Investigator
    Resource for Biocomputing, Visualization, and Informatics
    NIH/NCRR P41RR001081Jun 1, 1976 - Sep 14, 2012
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. J Biomol Screen. 2015 Jul; 20(6):788-800. Chimenti MS, Bulfer SL, Neitz RJ, Renslo AR, Jacobson MP, James TL, Arkin MR, Kelly MJ. PMID: 25690569.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    2. 13C NMR metabolomic evaluation of immediate and delayed mild hypothermia in cerebrocortical slices after oxygen-glucose deprivation. Anesthesiology. 2013 Nov; 119(5):1120-36. Liu J, Segal MR, Kelly MJ, Pelton JG, Kim M, James TL, Litt L. PMID: 23748856.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    3. 1H nuclear magnetic resonance brain metabolomics in neonatal mice after hypoxia-ischemia distinguished normothermic recovery from mild hypothermia recoveries. Pediatr Res. 2013 Aug; 74(2):170-9. Liu J, Sheldon RA, Segal MR, Kelly MJ, Pelton JG, Ferriero DM, James TL, Litt L. PMID: 23708689.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    4. Optimizing QSAR models for predicting ligand binding to the drug-metabolizing cytochrome P450 isoenzyme CYP2D6. Chem Biol Drug Des. 2011 Aug; 78(2):236-51. Saraceno M, Massarelli I, Imbriani M, James TL, Bianucci AM. PMID: 21575140.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. ACCF/AHA/AMA-PCPI 2011 performance measures for adults with coronary artery disease and hypertension: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures and the American Medical Association-Physician Consortium for Performance Improvement. Circulation. 2011 Jul 12; 124(2):248-70. Drozda J, Messer JV, Spertus J, Abramowitz B, Alexander K, Beam CT, Bonow RO, Burkiewicz JS, Crouch M, Goff DC, Hellman R, James T, King ML, Machado EA, Ortiz E, O'Toole M, Persell SD, Pines JM, Rybicki FJ, Sadwin LB, Sikkema JD, Smith PK, Torcson PJ, Wong JB. PMID: 21670226.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    6. Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. J Cereb Blood Flow Metab. 2011 Feb; 31(2):547-59. Liu J, Litt L, Segal MR, Kelly MJ, Yoshihara HA, James TL. PMID: 20717124.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    7. Binding characteristics of small molecules that mimic nucleocapsid protein-induced maturation of stem-loop 1 of HIV-1 RNA. Biochemistry. 2010 Aug 03; 49(30):6341-51. Chung J, Ulyanov NB, Guilbert C, Mujeeb A, James TL. PMID: 20565056.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    8. RNA structural motifs that entail hydrogen bonds involving sugar-phosphate backbone atoms of RNA. New J Chem. 2010 May 01; 34(5):910-917. Ulyanov NB, James TL. PMID: 20689681.
      View in: PubMed   Mentions:
    9. DOCK 6: combining techniques to model RNA-small molecule complexes. RNA. 2009 Jun; 15(6):1219-30. Lang PT, Brozell SR, Mukherjee S, Pettersen EF, Meng EC, Thomas V, Rizzo RC, Case DA, James TL, Kuntz ID. PMID: 19369428.
      View in: PubMed   Mentions: 187     Fields:    Translation:Cells
    10. Discovery of ligands for a novel target, the human telomerase RNA, based on flexible-target virtual screening and NMR. J Med Chem. 2008 Nov 27; 51(22):7205-15. Pinto IG, Guilbert C, Ulyanov NB, Stearns J, James TL. PMID: 18950148.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    11. Perspectives on NMR in drug discovery: a technique comes of age. Nat Rev Drug Discov. 2008 Sep; 7(9):738-45. Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James TL, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G. PMID: 19172689.
      View in: PubMed   Mentions: 89     Fields:    
    12. Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. J Biol Chem. 2008 Oct 17; 283(42):28757-66. Du Z, Fenn S, Tjhen R, James TL. PMID: 18701464.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    13. A small molecule, Lys-Ala-7-amido-4-methylcoumarin, facilitates RNA dimer maturation of a stem-loop 1 transcript in vitro: structure-activity relationship of the activator. Biochemistry. 2008 Aug 05; 47(31):8148-56. Chung J, Mujeeb A, Jiang Y, Guilbert C, Pendke M, Wu Y, James TL. PMID: 18616287.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    14. Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets. J Chem Inf Model. 2008 Jun; 48(6):1257-68. Guilbert C, James TL. PMID: 18510306.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    15. Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2391-6. Du Z, Lee JK, Tjhen R, Stroud RM, James TL. PMID: 18268334.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    16. Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices. Anesthesiology. 2007 Oct; 107(4):630-40. Zeng J, Liu J, Yang GY, Kelly MJ, James TL, Litt L. PMID: 17893460.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    17. Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates. Nucleic Acids Res. 2007; 35(18):6150-60. Ulyanov NB, Shefer K, James TL, Tzfati Y. PMID: 17827211.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    18. X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2. RNA. 2007 Jul; 13(7):1043-51. Du Z, Lee JK, Fenn S, Tjhen R, Stroud RM, James TL. PMID: 17526645.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    19. Resonance assignment of the first and second KH (hnRNP-K homology) domains of human poly(C)-binding protein-2 (PCBP2). J Biomol NMR. 2007 Jun; 38(2):197. Du Z, Fenn S, James TL. PMID: 17479348.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    20. Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res. 2007; 35(8):2651-60. Fenn S, Du Z, Lee JK, Tjhen R, Stroud RM, James TL. PMID: 17426136.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    21. Nucleocapsid protein-mediated maturation of dimer initiation complex of full-length SL1 stemloop of HIV-1: sequence effects and mechanism of RNA refolding. Nucleic Acids Res. 2007; 35(6):2026-34. Mujeeb A, Ulyanov NB, Georgantis S, Smirnov I, Chung J, Parslow TG, James TL. PMID: 17341460.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    22. Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA. Chem Biol. 2006 Sep; 13(9):993-1000. Mayer M, Lang PT, Gerber S, Madrid PB, Pinto IG, Guy RK, James TL. PMID: 16984889.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    23. Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab. 2007 Feb; 27(2):304-15. Zeng J, Yang GY, Ying W, Kelly M, Hirai K, James TL, Swanson RA, Litt L. PMID: 16736046.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    24. NMR structure of the full-length linear dimer of stem-loop-1 RNA in the HIV-1 dimer initiation site. J Biol Chem. 2006 Jun 09; 281(23):16168-77. Ulyanov NB, Mujeeb A, Du Z, Tonelli M, Parslow TG, James TL. PMID: 16603544.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    25. Refinement of Nucleic Acid Structures with Residual Dipolar Coupling Restraints in Cartesian Coordinate Space. Modern Magnetic Resonance, Edited by G.A. Webb. Dordrecht: Springer. 2006; 661-666. Ulyanov NB, Du Z, James TL. . View Publication.
    26. Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A. J Biol Chem. 2005 Nov 18; 280(46):38823-30. Du Z, Lee JK, Tjhen R, Li S, Pan H, Stroud RM, James TL. PMID: 16186123.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    27. Discovery of ligands by a combination of computational and NMR-based screening: RNA as an example target. Methods Enzymol. 2005; 394:571-87. Mayer M, James TL. PMID: 15808238.
      View in: PubMed   Mentions: 2     Fields:    
    28. Methods in Enzymology, Nuclear Magnetic Resonance of Biological Macromolecules, Vol. 394, 631 pages. New York: Elsevier. 2005. James TL Editor). .
    29. Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy. FEBS Lett. 2004 Nov 19; 577(3):415-21. Lapidot A, Vijayabaskar V, Litovchick A, Yu J, James TL. PMID: 15556620.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    30. Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses. Biochemistry. 2004 Sep 28; 43(38):11959-72. Du Z, Yu J, Ulyanov NB, Andino R, James TL. PMID: 15379536.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    31. Specific recognition of the C-rich strand of human telomeric DNA and the RNA template of human telomerase by the first KH domain of human poly(C)-binding protein-2. J Biol Chem. 2004 Nov 12; 279(46):48126-34. Du Z, Yu J, Chen Y, Andino R, James TL. PMID: 15331611.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    32. Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices. J Bioenerg Biomembr. 2004 Aug; 36(4):415-9. Zeng J, Hirai K, Yang GY, Ying W, Swanson RA, Kelly M, Mayer M, James TL, Litt L. PMID: 15377881.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    33. NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA. Biochemistry. 2004 May 18; 43(19):5757-71. Du Z, Ulyanov NB, Yu J, Andino R, James TL. PMID: 15134450.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    34. PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis. Brain Res Mol Brain Res. 2004 Apr 29; 124(1):51-61. Hirai K, Hayashi T, Chan PH, Zeng J, Yang GY, Basus VJ, James TL, Litt L. PMID: 15093685.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    35. Slow conformational dynamics in the hamster prion protein. Biochemistry. 2004 Apr 20; 43(15):4439-46. Kuwata K, Kamatari YO, Akasaka K, James TL. PMID: 15078089.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    36. NMR-based characterization of phenothiazines as a RNA binding scaffold. J Am Chem Soc. 2004 Apr 07; 126(13):4453-60. Mayer M, James TL. PMID: 15053636.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    37. NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106-126. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14790-5. Kuwata K, Matumoto T, Cheng H, Nagayama K, James TL, Roder H. PMID: 14657385.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    38. Dynamic NMR structures of [Rp]- and [Sp]-phosphorothioated DNA-RNA hybrids: is flexibility required for RNase H recognition? Biophys J. 2003 Oct; 85(4):2525-38. Tonelli M, Ulyanov NB, Billeci TM, Karwowski B, Guga P, Stec WJ, James TL. PMID: 14507715.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    39. Extending the family of UNCG-like tetraloop motifs: NMR structure of a CACG tetraloop from coxsackievirus B3. Biochemistry. 2003 Apr 22; 42(15):4373-83. Du Z, Yu J, Andino R, James TL. PMID: 12693932.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    40. Temperature control of respiring rat brain slices during high field NMR spectroscopy. Brain Res Brain Res Protoc. 2003 Feb; 10(3):191-8. Litt L, Hirai K, Basus VJ, James TL. PMID: 12565690.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    41. A molecular switch underlies a human telomerase disease. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):16998-7003. Comolli LR, Smirnov I, Xu L, Blackburn EH, James TL. PMID: 12482936.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    42. Detecting ligand binding to a small RNA target via saturation transfer difference NMR experiments in D(2)O and H(2)O. J Am Chem Soc. 2002 Nov 13; 124(45):13376-7. Mayer M, James TL. PMID: 12418877.
      View in: PubMed   Mentions: 9     Fields:    
    43. NMR structure of the 3' stem-loop from human U4 snRNA. Nucleic Acids Res. 2002 Oct 15; 30(20):4371-9. Comolli LR, Ulyanov NB, Soto AM, Marky LA, James TL, Gmeiner WH. PMID: 12384583.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    44. Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc? Biochemistry. 2002 Oct 15; 41(41):12277-83. Kuwata K, Li H, Yamada H, Legname G, Prusiner SB, Akasaka K, James TL. PMID: 12369815.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    45. Cytochrome c associated apoptosis during ATP recovery after hypoxia in neonatal rat cerebrocortical slices. J Neurochem. 2002 Oct; 83(2):309-19. Hirai K, Sugawara T, Chan PH, Basus VJ, James TL, Litt L. PMID: 12423241.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    46. In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR. Magn Reson Med. 2002 Sep; 48(3):430-9. Macdonald JM, Schmidlin O, James TL. PMID: 12210907.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    47. Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening. Chem Biol. 2002 Jun; 9(6):707-12. Du Z, Lind KE, James TL. PMID: 12079782.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    48. High-resolution NMR structure of an AT-rich DNA sequence. J Biomol NMR. 2002 Mar; 22(3):265-80. Ulyanov NB, Bauer WR, James TL. PMID: 11991355.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    49. Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. Chem Biol. 2002 Feb; 9(2):185-93. Lind KE, Du Z, Fujinaga K, Peterlin BM, James TL. PMID: 11880033.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    50. NMR structure of a gemcitabine-substituted model Okazaki fragment. Biochemistry. 2002 Jan 22; 41(3):839-46. Konerding D, James TL, Trump E, Soto AM, Marky LA, Gmeiner WH. PMID: 11790105.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    51. The Encyclopedia of Molecular Medicine. Edited by T.E. Creighton. New York: John Wiley & Sons. 2002; 3100-3102. James TL. Tat Protein. .
    52. Methods in Enzymology, Nuclear Magnetic Resonance of Biological Macromolecules, Part A, Vol. 338, 480 pages . New York: Academic Press. 2001. James TL, Dötsch V, Schmitz U (Editors).
    53. Methods in Enzymology, Nuclear Magnetic Resonance of Biological Macromolecules, Part B, Vol. 339, 454 pages. New York: Academic Press. 2001. James TL, Dötsch V, Schmitz U (Editors).
    54. Current Protocols in Nucleic Acid Chemistry. Edited by S.L. Beaucage, D.E. Bergstrom, G.D. Glick, and R.A. Jones. New York: John Wiley & Sons, Inc., 7.2. 2000; 1-15. James TL. NMR Determination of Oligonucleotide Structure. .
    55. Structure, Motion, Interaction and Expression of Biological Macromolecules. Proc. Eleventh Conversation in Biomolecular Structure & Dynamics. Edited by RH Sarma and MH Sarma. New York: Adenine Press, 11. 2000; 201-205. James TL, Lind KE, Filikov, AV, Mujeeb A. Three-Dimensional RNA Structure-Based Drug Discovery.
    56. A Small-Molecule Guanidinium Receptor: The Arginine Cork. Angew Chem Int Ed Engl. 1999 Sep; 38(17):2543-2547. Bell TW, Khasanov AB, Drew MG, Filikov A, James TL. PMID: 10508332.
      View in: PubMed   Mentions: 4     Fields:    
    57. Structure Computation and Dynamics in Protein NMR, Biological Magnetic Resonance, Edited by LJ Berliner and N Rama Krishna. Vol. 17, New York: Plenum Publ Corp. 1999; 201-222. Mujeeb A, Ulyanov NB, Billeci, TM, Farr-Jones S, James TL. Conformational Ensemble Calculations: Analysis of Protein and Nucleic Acid NMR Data. .
    58. Structure, Motion, Interaction and Expression of Biological Macromolecules. Proc. Tenth Conversation in Biomolecular Structure & Dynamics. Edited by RH Sarma and MH Sarma. New York: Adenine Press, 75-88. 1998. Ulyanov NB, Ivanov VI, Minyat EE, Khomyakova EB, Petrova MV, Lesiak K, James TL. Immobile Slipped-Loop Structures of DNA in Solution. .
    59. Nuclear Magnetic Resonance. Bethesda: Biophysical Society. Ch 1. 1998; 1-31. James TL. Fundamentals of NMR. .
    60. Molecular Modeling and Structure Determination of Nucleic Acids, Symposium Series, Number XX. Edited by NB Leontis and J Santa Lucia. American Chemical Society, Washington, DC. 1998; 181-194. Ulyanov NB, Mujeeb A, Donati A, Furrer P, Liu H, Farr-Jones S, Konerding DE, Schmitz U, T.L. James TL. Determination of Structural Ensembles from NMR Data: Conformational Sampling and Probability Assessment. .
    61. Biochemical Soc. Trans. 26. 1998; 481-486. Baldwin MA, James TL, Cohen FE, Prusiner SB. The Three-Dimensional Structure of PrP: Implications for Prion Disease.
    62. NOE Intensities from Multiple Conformations in Solution Analyzed by the Complete Relaxation Matrix Approach. Appl. Magn. Reson. 1998; 15:401-406. A. Donati, C. Rossi, S. Martini, N.B. Ulyanov, and T.L. James. .
    63. Oxford Handbook of Nucleic Acid Structure, Edited by S. Neidle. Oxford: Oxford University Press. 1998; 253-294. Schmitz U, Blocker FJH, James TL. Standard DNA Duplexes and RNA-DNA Hybrids in Solution. .
    64. Molecular Modeling and Structure Determination of Nucleic Acids, ACS Symposium Series, Edited by N.B. Leontis and J. Santa Lucia. American Chemical Society, 122-149. 1998. Lukavsky P, Billeci TM, James TL, Schmitz U. NMR Structure Determination of a 28-Nucleotide RNA from the Mammalian Signal Recognition Particle.
    65. NMR Spectroscopy of Biomolecules, Edited by J.L. Markley and S.J. Opella. New York: Oxford University Press, 340-357. 1997. Litt L, Espanol MT, Xu Y, Cohen Y, Chang L-H, P.R. Weinstein PR, Chan PH, James TL. Ex Vivo Multinuclear NMR Spectroscopy of Perfused, Respiring Rat Brain Slices: Model Studies of Hypoxia, Ischemia, and Excitotoxicity.
    66. Biological Structure and Dynamics, Proceedings of the Ninth Conversation in Biomolecular Structure and Dynamics. Edited by R.H. Sarma and M.H. Sarma. New York: Adenine Press, Vol. 2, 165-187. 1996. Schmitz U, Gonzales C, Ulyanov NB, Blocker, FH, Liu H, James TL. Structural Ensembles from NMR Data: Applications to Nucleic Acids. .
    67. NMR as a Structural Tool for Macromolecules: Current Status and Future Directions, Edited by B.D. Nageswara Rao and M.D. Kemple. New York: Plenum Publishing Corp., 191-206. 1996. T.L. James TL, Gonzalez C, Liu, H, Schmitz U, Ulyanov NB. Dynamic Structure of Nucleic Acid Duplexes.
    68. Peptides: Chemistry, Structure and Biology, Edited by P.T.P. Kaumaya and R.S. Hodges. Leiden: ESCOM Science Publishers B.V., 468-470. 1996. Baldwin MA, Zhang H, Bekker T, Zhou S, Nguyen JT, Kolbert AC, Heller J, James TL, Wemmer DE, Pines A, Cohen FE, Prusiner SB. Synthetic Peptides Model a-helix-b-sheet Conformational Changes in the Prion Protein.
    69. Methods in Enzymology, Nuclear Magnetic Resonance and Nucleic Acids, Vol. 261, 644 pages. New York: Academic Press. 1995. James TL (Editor). .
    70. Encyclopedia of Nuclear Magnetic Resonance. Edited by D.M. Grant and R.K. Harris. New York: John Wiley & Sons, 3320-3331. 1995. James TL. Determination of Sequence-Dependent Nucleic Acid Structures in Solution. .
    71. Methods in Enzymology, Nuclear Magnetic Resonance and Nucleic Acids, Edited by T.L. James. New York: Academic Press, Vol. 261, 3-44. 1995. Schmitz U, James TL. How to Generate Accurate Solution Structures of Double-Helical Nucleic Acid Fragments Using Nuclear Magnetic Resonance and Restrained Molecular Dynamics. .
    72. Methods in Enzymology, Nuclear Magnetic Resonance and Nucleic Acids. Edited by T.L. James. New York: Academic Press, Vol. 261. 1995; 90-121. Ulyanov NB, James TL. Statistical Analysis of DNA Duplex Structural Features. .
    73. Encyclopedia of Nuclear Magnetic Resonance. Edited by D.M. Grant and R.K. Harris. New York: John Wiley & Sons. 1995. James TL. Historical Sketch: Time for Preparation and Evolution. But What is the Mechanism for Relaxation?. .
    74. Book Review on "Nucleic Acid Targeted Drug Design. Edited by C.L. Propst and T.J. Perun. New York: Marcel Dekker, 1992". 1994. James TL. J. Amer. Chem. Soc., 116, 9412.
    75. Computational Strategies Pertinent to NMR Solution Structure Determination. Current Opinion in Structural Biology. 1994; 4:275-284. James, T.L.
    76. Methods in Enzymology, Nuclear Magnetic Resonance, Part C. Vol 239, 813 pages. New York: Academic Press. 1994. James TL, Oppenheimer NJ (Editors).
    77. Methods in Enzymology, Nuclear Magnetic Resonance, Part C. Edited by T.L. James and N.J. Oppenheimer. New York: Academic Press, Vol. 239. 1994; 416-439. James TL. Assessment of the Quality of Derived Macromolecular Structures. .
    78. Structural Biology: The State of the Art. Proc. Eighth Conversation in Biomolecular Structure & Dynamics. Vol. 2, pp. 251-272. Edited by R.H. Sarma and M.H. Sarma. New York: Adenine Press. 1994. James TL. High Resolution DNA Solution Structures: Genome Target Refinement Using Interproton Distance and Torsion Angle Restraints. .
    79. Study of Biological Macromolecules by Nuclear Magnetic Resonance Spectroscopy. Edited by C.L. Stassinopoulou. NATO ASI Series Volume. Berlin: Springer-Verlag , Vol H87. 1994; 335-348. James TL, Bishop KD, Blocker F, Gonzalez C, Kumar A, Liu H, Mujeeb A, Schmitz U, Ulyanov NB, Yuan Y-C, Weisz K. Determination of High-Resolution, Sequence-Dependent DNA Duplex Structures in Solution.
    80. Proceedings of the Twenty-Third European Peptide Symposium. Edited by H.L.S. Maia, Leiden: ESCOM Science Publishers B.V., 580-581. 1994. Baldwin MA, Nguyen JT, Zhang H, Pan KM, Huang Z, Livshits TL, Kaneko K, Cohen FE, James TL, Prusiner SB. Conformational Changes in the Prion Protein Can be Simulated with Synthetic Peptides.
    81. New Methods in Drug Research, Vol. 4. Edited by A. Makriannis. Barcelona: Prous. 1993. James TL, Kerwood DJ, Gochin M, Mills PA, Borgias BA, Basus VJ. Refinement of Three-Dimensional Protein and DNA Structures in Solution from Two-Dimensional NMR Spectra.
    82. J. Magn. Reson. 1993. Liu, H., Weisz, K. and James, T.L. Tailored Excitation by Shaped RF Pulses: Optimization and Implementation of Excitation Containing a Notch.
    83. Extracting Accurate Distances and Bounds from 2D NOE Exchangeable Proton Peaks. J. Am. Chem Soc. 1993; 115:1590-1591. Liu, H., Kumar, A., Weisz, K., Schmitz, U., Bishop, K.D., and James, T.L.
    84. Averaging of Cross-Relaxation Rates and Distances for Methyl, Methylene and Aromatic Ring Protons Due to Motion or Overlap: Extraction of Accurate Distances Iteratively via Relaxation Matrix Analysis of 2D NOE Spectra. J. Magn. Reson. 1992; 98:163-175. Liu, H., Thomas, P.D., and James, T.L.
    85. Refinement of Three-Dimensional Biopolymer Structures in Solution Using NMR Data. Chemical Design Automation News. 1992; 7:19-27. James, TL.
    86. Solvent-Suppression Pulses. III. Design Using Simulated-Annealing Optimization with in Vitro and in Vivo Testing. J Magn Reson. 1992; 96:345-362. Smith V, Kurhanewicz J, James TL. .
    87. Dynamic Interpretation of NMR Data: Molecular Dynamics with Weighted Time-Averaged Restraints and Ensemble R-Factor. J. Am. Chem. Soc. 1992; 114:10654-10655. Schmitz, U., Kumar, A. and James, T.L.
    88. Detection of Phosphorus Metabolites in Human Prostrates with a Transrectal Phosphorus-31 NMR Probe. J. Magn. Reson. 1992; 99:377-386. Thomas, M.A., Narayan, P., Kurhanewicz, J., Jajodia, P., James, T.L., and Weiner, M.
    89. Biol Magn Reson, Edited by L.J. Berliner and J. Reuben. New York: Plenum Press. 1992; 135-158. Chang L-H, James TL. NMR Methods in Studies of Brain Ischemia. .
    90. Macromolecule Structure Refinement by Relaxation Matrix Analysis of 2D NOE Spectra: Effect of Differential Internal Motion on Internuclear Distance Determination in Proteins. Israel J. of Chem. 1992; 32:257-261. Kumar, A., James, T.L., and Levy, G.C.
    91. Solvent-Suppression Pulses. I. Design Using Optimal Control Theory. J Magn Reson. 1991; 95:41-60. Smith V, Kurhanewicz J, James TL. .
    92. Solvent-Suppression Pulses. II. In Vitro and In Vivo Testing of Optimal Control Theory Pulses. J Magn Reson. 1991; 95:61-70. Smith V, Kurhanewicz J, James TL. .
    93. Ann NY Acad Sci, 625,. 1991; 707-724. Litt L, Lockhart S, Cohen Y, Yasuda N, Kim F, Freire B, Laster M, Peterson N, Taheri S, Chang L-H, Sessler DI, Moseley M, Eger II EI, James TL. In Vivo 19F NMR Brain Studies of Halothane, Isoflurane, and Desflurane: Rapid Elimination and No Abundant Saturable Binding.
    94. Computational Aspects of the Study of Biological Macromolecules by NMR. Edited by J.C. Hoch, F.M. Poulsen, and D. Redfield. NATO ASI Series, Vol. 225. New York: Plenum Press. 1991; 331-347. James TL, Gochin M, Kerwood DJ, Pearlman DA, Schmitz U, Thomas PD. Refinement of Three-Dimensional Protein and DNA Structures in Solution from NMR Data.
    95. Ann. Rev. Phys. Chem. 42, 501-542. 1991. James TL, Basus VJ. Generation of High-Resolution Protein Structures in Solution from Multidimensional NMR.
    96. NMR and Biomolecular Structure, Edited by I. Bertini, H. Molinari, and N. Niccolai. Weinheim: VCH Verlagsgesellschaft. 1991; 87-111. James TL, Borgias B, Bianucci AM, Zhou N. Solution Structure Refinement Using Complete Relaxation Matrix Analysis of 2D NOE Experiments: DNA Fragments.
    97. Conformations and Forces in Protein Folding, Edited by B.T. Nall and K.A. Dill. Washington: Amer Soc Adv Sci. 1991; 86-114. Naderi HM, Thomason JF, Borgias BA, Anderson S, James TL, I.D. Kuntz ID. 1H NMR Assignments and Three-Dimensional Structure of Ala14/Ala38 Bovine Pancreatic Trypsin Inhibitor Based on Two-Dimensional NMR and Distance Geometry.
    98. Relaxation Matrix Analysis of Two-Dimensional Nuclear Overhauser Effect Spectra to Obtain Accurate Biomolecular Structural Constraints and to Assess Structural Quality. Current Opinion in Structural Biology. 1991; 1:1042-1053. James TL. .
    99. Absence of abundant binding sites for anesthetics in rabbit brain: an in vivo NMR study. Anesthesiology. 1990 Sep; 73(3):455-60. Lockhart SH, Cohen Y, Yasuda N, Kim F, Litt L, Eger EI, Chang LH, James T. PMID: 2393130.
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    100. Frontiers of NMR in Molecular Biology, UCLA Symposium on Molecular and Cellular Biology, Vol. 109, Edited by D. Live, I. Armitage, and D. Patel. New York: Alan R. Liss, Inc. 1990; 271-274. James TL. DNA/RNA and Ligand Interactions. .
    101. MARDIGRAS –– A Procedure for Matrix Analysis of Relaxation for Discerning Geometry of an Aqueous Structure. J Magn Reson. 1990; 87:475-487. Borgias BA, James TL. .
    102. NMR Applications in Biopolymers, Edited by J.W. Finley, S.J. Schmidt, and J.S. Serianni. New York: Plenum Press. 1990; 135-154. James TL, Borgias BA, Bianucci AM, Zhou N. Determination of DNA and Protein Structure in Solution via Complete Relaxation Matrix Analysis of 2D NOE Spectra.
    103. Progress in Nuclear Magnetic Resonance Spectroscopy, Edited by J.W. Emsley, J. Feeney, and L.H. Sutcliffe. Oxford: Pergamon Press. 1990; 83-100. Borgias BA, Gochin M, Kerkwood DJ, James TL. Relaxation Matrix Analysis of 2D NMR Data . .
    104. Biol Magn Reson. 1990; 119-155. Borgias BA, James TL. Structure Determination via Complete Relaxation Matrix Analysis (CORMA) of Two-Dimensional Nuclear Overhauser Effect Spectra: DNA Fragments. Edited by LJ Berliner and Reuben J. New York: Plenum Press. .
    105. Frontiers of NMR in Molecular Biology, UCLA Symposium on Molecular and Cellular Biology, Vol. 109, Edited by D. Live, I. Armitage, and D. Patel. New York: Alan R. Liss, Inc. 1990; 177-187. James TL, Borgias BA. Determination of DNA and Protein Structures via Complete Relaxation Matrix Analysis of 2D NOE Spectra.
    106. Neurotransmission and Cerebrovascular Function, Vol. I, Edited by J Seylaz & T MacKenzie. Amsterdam: Elsevier. 1989; 423-427. Cohen Y, Chang L-H, Litt L, James TL. In Vivo Measurements of Brain Glutamate/Glutamine Using 1H NMR Spectroscopy: Problems and Promises. .
    107. Methods in Enzymology, NMR Techniques, Part A: Spectral Techniques and Dynamics,Vol 176, Edited by NJ Oppenheimer and TL James. New York: Academic Press. 1989; 169-183. Borgias BA, James TL. 2D NOE Complete Relaxation Matrix Analysis. .
    108. Methods in Enzymology, Nuclear Magnetic Resonance, Part B: Structure and Mechanism, Vol. 177, 507 pages. New York: Academic Press. 1989. Oppenheimer NJ, James TL (Editors). .
    109. Methods in Enzymology, Nuclear Magnetic Resonance, Part A: Spectral Techniques and Dynamics. Vol 176, 530 pages. New York: Academic Press. 1989. Oppenheimer NJ, James TL (Editors). .
    110. Spatially Localized COSY Spectra from a Surface Coil Using Phase-Encoding Magnetic Field Gradients. J Magn Reson. 1989; 85:203-208. Cohen Y, Chang L-H, Litt L, James TL. .
    111. In Advances in Surgery for Cerebral Stroke. Edited by J. Suzuki. Tokyo: Springer-Verlag. 1988; 633-637. Shirane R, Chang L-H, Weinstein PR, James TL. Sequential Changes of Brain Metabolism during Temporary Global Ischemia in the Rat Detected by Simultaneous 1H and 31P NMR Spectroscopy. .
    112. NMR Spectroscopy and Drug Development. 1988; 358-379. James TL, Borgias BM, Bianucci AM, Jamin N, Pattabiraman N, Suzuki E-I, Zhou N, Zon G. Molecular Structure Determination via Complete Relaxation Matrix Analysis of 2D NOE Spectra and Molecular Mechanics: Application to DNA Fragments.
    113. The Modulation Theorem in Tailored Radiofrequency Excitation: Application to a Notch Filter. J Magn Reson. 1988; 78:308-313. Gonzalez-Mendez R, Engeseth H, Gibson AAB, de Olivares J, Litt L, James TL . .
    114. 31P NMR of "In Vivo" Insulted Rat Brain. Physica Medica. 1988; 1:13-21. Pogliani L, T.L. James TL, Laschi LH, N. Ishige N, Pitts LH.
    115. COMATOSE: A Method for Constrained Refinement of Macromolecular Structure Based on Two-Dimensional Nuclear Overhauser Effect Spectra. J Magn Reson. 1988; 79:493-512. Borgias BA, James TL. .
    116. The preventive effect of verapamil on ethanol-induced cardiac depression: phosphorus-31 nuclear magnetic resonance and high-pressure liquid chromatographic studies of hamsters. Circulation. 1987 May; 75(5):1058-64. Wu S, White R, Wikman-Coffelt J, Sievers R, Wendland M, Garrett J, Higgins CB, James T, Parmley WW. PMID: 3568306.
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    117. In Situ Brain Metabolism. Ann NY Acad Sci. 1987; 508:64-80. James TL, Chang L-H, Chew W, Gonzalez-Mendez R, Litt L, Mills P, Moseley M, Pereira B, Sessler DI, Weinstein PR.
    118. A Balance-Matched Double-Tuned Probe for In Vivo 1H and 31P NMR. J Magn Reson. 1987; 72:168-172. Chang L-H, Chew WM, Weinstein PR, James TL. .
    119. 1987; 64-80. James TL, Chang L-H, W. Chew W, Gonzalez-Mendez R, Litt L, Mills P, Moseley M, Pereira B, Sessler DI, Weinstein PR. In Situ Brain Metabolism. In Physiological NMR Spectroscopy: From Isolated Cells to Man, Edited by S.M. Cohen. Ann. N.Y. Acad. Sci., Vol 508.
    120. The Swift Method for In Vivo Localized Excitation (SMILE). J Magn Reson. 1987; 75:523-528. Chew WM, Chang L-H, Flamig DP, James TL. .
    121. 1987; 107-113. Moseley ME, Chew WM, Brant-Zawadzki M, James TL. Magnetic Resonance Spectroscopy: Principles and Potential Applications. In Magnetic Resonance in the Central Nervous System. Edited by M. Brant-Zawadzki and D. Norman. New York: Raven Press. .
    122. Principles of Magnetic Resonance Spectroscopy. Appl Radiol. 1987; 16:40-52. James TL, Chew WM, Giannini DD, Gonzalez-Mendez R, Moseley ME, Pogliani L, Vigneron D .
    123. Evaluation of the Hereditary Syrian Hamster Cardiomyopathy by 31P Nuclear Magnetic Resonance Spectroscopy: Improvement After Acute Verapamil Therapy. Circulation Research. 1987; 59:597-604. Markiewicz W, Wu SS, Parmley WW, Higgins CB, Sievers R, James TL, Wikman-Coffelt J, Jasmin G.
    124. 31P NMR Results of In Vivo Insulted Rat Brain. A Qualitative Interpretation of the Metabolic Changes. Physica Medica. 1987; 1:35-41. Pogliani L, Valensin G, Pitts LH, Ishige N, James TL. .
    125. 1987; 503-514. James TL, Suzuki E-I, N. Pattabiraman N, Zon G. Detailed Structure Determination of DNA Fragments Using Complete Relaxation Matrix Analysis of Two-Dimensional NMR Spectra, Molecular Mechanics Calculations and Computer Graphics. In Biophosphates and Their Analogues. Synthesis, Metabolism, and Activity. Edited by K.S. Bruzik and W.J. Stec. Amsterdam: Elsevier Science, .
    126. Precision Mapping of the B1 Field Using the Rotating Frame Experiment. J Magn Reson. 1987; 73:293-299. Murphy-Boesch J, So G, James TL. .
    127. Localized tissue MR spectroscopy. AJR Am J Roentgenol. 1986 Dec; 147(6):1327-8. Margulis AR, James TL. PMID: 3490773.
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    128. 2D NOE Full Relaxation Matrix Analysis and Molecular Mechanics Calculations for Structure Determination in Solution: DNA Fragments. Bull Magn Reson. 1986; 8:152-156. James TL, Suzuki E-I, Pattabiraman N, Zon G.
    129. 1986; 81-108. James TL, Broido MS, Jamin N, Young GB, Zon G. Structure and Dynamics via Two-dimensional NMR. Illustrations with DNA Fragments. In Advanced Magnetic Resonance Techniques in Systems of High Molecular Complexity. Edited by N. Nicolai and G. Valensin. Boston: Birkhauser.
    130. Technical Obstacles Hinder Spread of MR Spectroscopy. Diagnostic Imaging. 1986; 8:218-221. James TL. .
    131. Magnetic Resonance Spectroscopy: Principles and Potential Application. Applied Radiol. 1986; 16:40-52. James TL, Chew WM, Giannini DD, Gonzalez-Mendez R, Moseley ME, Pogliani L, Vigneron D .
    132. Localized Tissue MR Spectroscopy. Am J Roentgenol. 1986; 147:1327-1328. Margulis AR, James TL . .
    133. AUR memorial Award. Induced alignment of flowing sickle erythrocytes in a magnetic field. A preliminary report. Invest Radiol. 1985 Sep; 20(6):560-6. Brody AS, Sorette MP, Gooding CA, Listerud J, Clark MR, Mentzer WC, Brasch RC, James TL. PMID: 2933361.
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    134. Selective Inversion with Surface Coils: Use of Depth Pulses for the Inversion Transfer Experiment In Vivo. J Magn Reson. 1985; 65:516-521. Gonzalez-Mendez R, Moseley ME, Murphy-Boesch J, Chew WM, Litt L, James TL . .
    135. 1985; 141-148. James TL, Gonzalez-Mendez R, Litt L. Magnetic Resonance Spectroscopy: Principles and Potential Application in Medicine. Chapter in Contemporary Imaging. Edited by H.I. Goldberg, C.B. Higgins, and E.J. Ring. San Francisco: Radiology Research and Education Foundation.
    136. 1985; 553-562. James TL, Young GB, Broido MS, Keepers JW, Jamin N, Zon G. Quantitative Internuclear Distances via 2D NMR Spectra: A Test Case and DNA Octamer Duplex. In Proceedings of the International Symposium on Biomolecular Structure and Interactions. Edited by V. Sasisekharan and K.R.K. Easwaran.
    137. 1985; 33-52. James TL, In Vivo Nuclear Magnetic Resonance Spectroscopy. Article in Workshop on Advances in NASA-Relevant, Minimally Invasive Instrumentation, April 25-27, 1984, Asilomar, California. Pasadena: NASA Jet Propulsion Laboratory.
    138. 1985; 1-30. James TL, Phosphorus-31 NMR as a Probe for Phosphoproteins. In CRC Critical Reviews in Biochemistry, Vol. 18, Edited by G.D. Fasman. Boca Raton: CRC Press.
    139. 1984; 7-22. James TL, Basic Nuclear Magnetic Resonance Principles. Chapter 2 in Biomedical Magnetic Resonance. Edited by T.L. James and A.R. Margulis. San Francisco: Radiology Research and Education Foundation.
    140. 1984; 235-244. James TL, In Vivo Nuclear Magnetic Resonance Spectroscopy. Chapter in NMR, CT, and Interventional Radiology. Edited by A.A. Moss, E.J. Ring, and C.B. Higgins. San Francisco: Radiology Education and Research Foundation.
    141. 1984; 267-271. Moseley ME, Chew WM, James TL. Sodium-23 Magnetic Resonance Imaging. Chapter 18 in Biomedical Magnetic Resonance. Edited by T.L. James and A.R. Margulis. San Francisco: Radiology Research and Education Foundation. .
    142. 1984; 349-400. James TL. Relaxation Behavior of Nucleic Acids. Dynamics and Structure. Chapter 12 in Phosphorus-31 NMR. Principles and Applications, Edited by D. Gorenstein. New York: Academic Press.
    143. A Theoretical Study of Distance Determinations from NMR. Two-Dimensional Nuclear Overhauser Effect Spectra. J Magn Reson. 1984; 57:404-426. Keepers JW, James TL. .
    144. Comparison of 31P NMR Spectra of In Vivo Rat Brain Using Convolution Difference and Saturation with a Surface Coil. Source of the Broad Component in the Brain Spectrum. J Magn Reson. 1984; 57:526-533. Gonzales-Mendez R, Litt L, Koretsky AP, von Colditz J, Weiner MW, James TL. .
    145. Proton Nuclear Magnetic Resonance Spectroscopy of Normal and Edematous Brain Tissue In Vitro: Changes in Relaxation during Tissue Storage. Magn Reson Imaging. 1984; 2:205-209. Moseley ME, Nishimura MC, Pitts LH, Bartkowski HM, James TL . .
    146. Biomedical Magnetic Resonance, San Francisco: Radiology Research and Education Foundation. 1984; 1-462. James TL, Margulis AR (Editors).
    147. Determination of Molecular Structure in Solution via Two-Dimensional Nuclear Overhauser Effect Experiments: Proflavine as a Rigid Molecule Test Case. J Amer Chem Soc. 1984; 106:7986-7988. Young GB, James TL. .
    148. 1984; 1-6. James TL, Margulis AR. Historical Development of Biomedical Magnetic Resonance. Chapter 1 in Biomedical Magnetic Resonance, Edited by T.L. James and A.R. Margulis. San Francisco: Radiology Research and Education Foundation.
    149. Energy levels at systole vs. diastole in normal hamster hearts vs. myopathic hamster hearts. Circ Res. 1983 Dec; 53(6):759-66. Sievers R, Parmley WW, James T, Wikman-Coffelt J. PMID: 6640862.
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    150. Physicochemical characterization of large unilamellar phospholipid vesicles prepared by reverse-phase evaporation. Biochim Biophys Acta. 1983 Jul 13; 732(1):289-99. Düzgünes N, Wilschut J, Hong K, Fraley R, Perry C, Friend DS, James TL, Papahadjopoulos D. PMID: 6688185.
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    151. 13C-n.m.r.-spectral study of galactosyltransferase specificity with regard to the carbohydrate side-chain of native ovalbumin. Carbohydr Res. 1983 Feb 16; 113(1):141-50. Berman E, James TL. PMID: 6404553.
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    152. 1983; 42-48. Koretsky A, Straus W, Basus V, Murphy J, Bendel P, James T, Weiner M. Feasibility of 31P NMR to Study Metabolic Effects of Renal Ischemia In Vivo. Proceedings of the Eighth International Congress on Nephrology, Satellite Symposium on Acute Renal Failure, Edited by H.E. Eliahu. New York: Saunders.
    153. 1983; 155-167. James TL, Bendel P, James JL, Keepers JW, Kollman PA, Lapidot A, Murphy-Boesch J, Taylor JE. Conformational Flexibility of Nucleic Acids. Chapter in Nucleic Acids: The Vectors of Life, . Edited by B. Pullman and J. Jortner. D. Reidel.
    154. Conformational Flexibility in Nucleic Acids Investigated by NMR Relaxation. Bull Magn Reson. 1983; 4:119-159. James TL . .
    155. NMR of Nucleic Acids. Magn Reson Rev. 1983; 8:139-163. James TL, Schmidt PG.
    156. The Dynamic Structure of Nucleic Acids. Bull Magn Reson. 1983; 5:165-167. James TL, Bendel P, Keepers JW, Taylor JE .
    157. 13P NMR Spectroscopy of Rat Organs, In Situ, Using Chronically Implanted Radiofrequency Coils. Proc Nat Acad Sci. 1983; 80:7491-7495. Koretsky AP, Wang S, Murphy-Boesch J, Klein MP, James TL, Weiner MW.
    158. 1983; 41-51. James TL. Basic Principles and Biological Research Applications. Chapter 5 in Clinical Magnetic Resonance Imaging. Edited by A.R. Margulis, C.B. Higgins, L. Kaufman, and L.E. Crooks. San Francisco: Radiology Research and Education Foundation.
    159. An NMR study of 13C-enriched galactose attached to the single carbohydrate chain of hen ovalbumin. Motions of the carbohydrates of glycoproteins. J Biol Chem. 1982 Feb 25; 257(4):1829-35. Goux WJ, Perry C, James TL. PMID: 7056747.
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    160. Transverse Relaxation of 31P in 5'-AMP. J Magn Reson. 1982; 48:76-85. Bendel P, James TL. .
    161. Models for DNA Backbone Motions: An Interpretation of NMR Relaxation Experiments. J Amer Chem Soc. 1982; 104:929-939. Keepers JW, James TL. .
    162. Molecular Motions of Supercoiled and Circular-DNA. A Phosphorus-31 Nuclear Magnetic Resonance Study. J Am Chem Soc. 1982; 104:6748-6753. Bendel P, Laub O, James TL . .
    163. 1982; 111-118. Edmondson DE, James TL. Physical and Chemical Studies on the FMN and Non-Flavin Phosphate Residues in Azotobacter Flavodoxin. Chapter 20 in Flavins and Flavoproteins, Edited by V. Massey and C.H. Williams. Amsterdam: Elsevier North Holland, Inc.
    164. Fast and Slow Conformational Fluctuations of RNA and DNA. Subnanosecond Internal Motion Correlation Times Determined by 31P NMR. J Am Chem Soc. 1980; 102(1):25-31. Bolton PH, James TL. .
    165. Internal Motions in Proteins Examined by 13C NMR Rotating Frame Spin-Lattice Relaxation: Chymotrypsinogen. J Magn Reson. 1980; 39:141-153. James TL. .
    166. Spectral studies on the interaction of dichloromethane with hemoglobin. Mol Pharmacol. 1979 Nov; 16(3):1065-74. Harkey MR, Settle WL, James TL, Trevor AJ. PMID: 530249.
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    167. Unfolding of Ribonuclease A by Guanidinium Chloride. Protein Internal Motions Studied by Nuclear Magnetic Resonance Spin-Lattice Relaxation in an Off-Resonance Rotating Frame. J Am Chem Soc. 1979; 101(23):7050-7055. James TL, Sawan SP.
    168. Molecular Motions in RNA and DNA Investigated by Phosphorus-31 and Carbon-13 NMR Relaxation. J Phys Chem. 1979; 83(26):3359-3366. Bolton PH, James TL. .
    169. Proton NMR Assignments for Cholesterol. Use of Deuterium NMR as an Assignment Aid. J Magn Reson. 1979; 35:409-414. Sawan SP, James TL, Gruenke LD, Craig JC.
    170. Line Narrowing Induced by Selective Population Transfer. J Magn Reson. 1979; 36:443-446. Bolton PH, James TL. .
    171. Rotating Frame Spin-Lattice Relaxation in the Presence of an Off-Resonance Radiofrequency Field. Scalar Relaxation of 31P in PBr3. J Magn Reson. 1979; 33:345-353. James TL, Matson GB.
    172. Chapter 14 in NMR and Biochemistry. A Symposium Honoring Mildred Cohn. Edited by SJ Opella and P Lu. 1979; 211-223. James TL. Study of Protein Mobility Using Rotating Frame Spin-Lattice Relaxation in the Presence of an Off-Resonance rf Field. .
    173. Use of a Plastic Tube Insert for NMR Experiments Entailing Hazardous Samples. J Magn Reson. 1978; 32:173-174. Sawan SP, James TL. .
    174. Protein Rotational Correlation Times Determined in Aqueous Solution by Carbon-13 Rotating Frame Spin-Lattice Relaxation in the Presence of an Off-Resonance Radiofrequency Field. J Am Chem Soc. 1978; 11(100): 3590-3594. James TL, Matson GB, Kuntz ID.
    175. Rotating Frame Spin-Lattice Relaxation in the Presence of an Off-Resonance Radiofrequency Field. Investigation of Intermediate Molecular Motion. J Magn Reson. 1977; 28:417-426. James TL, Matson GB, Kuntz ID, Fisher RW, Buttlaire DH .
    176. ACS Symposium Series. Biochemistry Involving Carbon-Fluorine Bonds. 1976; 57-76. Santi DV, Pogolotti AL, James TL, Wataya Y, Ivanetich KM, Lam SSM. Thymidylate Synthetase: Interaction with 5-Fluoro and 5-Trifluoromethyl-2'-Deoxyuridylic Acid.
    177. ACS Symposium Series. Magnetic Resonance in Colloid and Interface Science. 1976; 499-503. Kuntz ID, Zipp A, James TL. Motions of Water in Biological Systems. Chapter 40 in Magnetic Resonance in Colloid and Interface Science, pp. 499-503. ACS Symposium Series, Number 34. Edited by H.A. Resing and C.G. Wade. American Chemical Society, 1976.
    178. An Investigation of "Bound" Water in Frozen Erythrocytes by Proton Magnetic Resonance Spin-Lattice, Spin-Spin, and Rotating Frame Spin-Lattice Relaxation Time Measurements. J Magn Reson. 1976; 24:411-424. Zipp A, Kuntz ID, James TL. .
    179. Outpatient phenothiazine use and bone marrow depression. A report from the drug epidemiology unit and the Boston collaborative drug surveillance program. Arch Gen Psychiatry. 1975 Nov; 32(11):1416-8. Swett C. PMID: 978.
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    180. The effect of adrenaline and of alpha- and beta-adrenergic blocking agents on ATP concentration and on incorporation of 32Pi into ATP in rat fat cells. Biochem Pharmacol. 1975 Sep 15; 24(18):1659-62. Stein JM. PMID: 12.
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    181. Action of propranolol on mitochondrial functions--effects on energized ion fluxes in the presence of valinomycin. Biochem Pharmacol. 1975 Sep 15; 24(18):1701-5. Järvisalo J, Saris NE. PMID: 13.
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    182. Formate assay in body fluids: application in methanol poisoning. Biochem Med. 1975 Jun; 13(2):117-26. Makar AB, McMartin KE, Palese M, Tephly TR. PMID: 1.
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    183. Nuclear Magnetic Resonance in Biochemistry. 1975; 413 pages. James TL. .
    184. Measurement of the Self-Diffusion Coefficient of Each Component in a Complex System Using Pulsed-Gradient Fourier Transform NMR. J Magn Reson. 1973; 11:58-61. James TL, McDonald GG.
    185. Pulsed Nuclear Magnetic Resonance Measurement of Relaxation Times in Ion-Exchange Resins. Anal Chem. 1972; 44(6):982-985. Blaedel WJ, Brower LE, James TL, Noggle JH.
    186. 23Na NMR Studies of Sodium Ion Interactions: Cysteine, Aspartic Acid, and Citric Acid. Bioinorg Chem. 1972; 2:69-74. James TL, Noggle JH .
    187. Photoelectron Spectroscopy. J Chem Educ. 1971; 48(11):712-718. James TL. .
    188. Nuclear Magnetic Resonance Studies of Sodium Aminocarboxylic Acid Complexes. PhD Dissertation, University of Wisconsin, Madison. 1969. James TL. .
    189. Sodium-23 Nuclear Magnetic Resonance Studies of Sodium Aminocarboxylic Acid Complexes. J Am Chem Soc. 1969; 91(13):3424-2428. James TL, Noggle JH.
    190. A Comparison of the Proton Affinities of Neutral Oxygen and Sulfur in Chelating Ligands. J Phys Chem. 1969; 73(3):634-640. James TL, Kula RJ.
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