Thomas Lemmin, PhD

SchoolUCSF School of Pharmacy
DepartmentPharmaceutical Chemistry
Address555 Mission Bay Blvd South
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    National Institute of HealthPostdoctoral IRTA2015Vaccine Research Center
    Ecole Polytechnique Fédérale de LausannePhD2013Institute of Bioengineering
    Universität ZürichResearch assistant2008Department of Neuroradiology
    Ecole Polytechnique Fédérale de LausanneMaster of Science2007Electrical Engineering and Electronics, Information Technology
    Ecole Polytechnique Fédérale de LausanneMinor2007Biomedical Engineering
    Ecole Polytechnique Fédérale de LausanneBachelor of Science2005Electrical Engineering and Electronics

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Markiewicz BN, Lemmin T, Zhang W, Ahmed IA, Jo H, Fiorin G, Troxler T, DeGrado WF, Gai F. Infrared and fluorescence assessment of the hydration status of the tryptophan gate in the influenza A M2 proton channel. Phys Chem Chem Phys. 2016 Oct 19; 18(41):28939-28950. PMID: 27725984.
      View in: PubMed
    2. Audagnotto M, Lemmin T, Barducci A, Dal Peraro M. Effect of the Synaptic Plasma Membrane on the Stability of the Amyloid Precursor Protein Homodimer. J Phys Chem Lett. 2016 Sep 15; 7(18):3572-8. PMID: 27518597.
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    3. Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stöhr J, Hong M. Structural Polymorphism of Alzheimer's ß-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study. J Am Chem Soc. 2016 Aug 10; 138(31):9840-52. PMID: 27414264.
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    4. Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, Druz A, Georgiev IS, Gorman J, Huang J, Joyce MG, Louder MK, Ma X, McKee K, O'Dell S, Pancera M, Yang Y, Blanchard SC, Mothes W, Burton DR, Koff WC, Connors M, Ward AB, Kwong PD, Mascola JR. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science. 2016 May 13; 352(6287):828-33. PMID: 27174988.
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    5. Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, Kwon YD, Pancera M, Taft J, Yang Y, Zhang B, Shivatare SS, Shivatare VS, Lee CC, Wu CY, Bewley CA, Burton DR, Koff WC, Connors M, Crispin M, Baxa U, Korber BT, Wong CH, Mascola JR, Kwong PD. Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G. Cell. 2016 May 5; 165(4):813-26. PMID: 27114034.
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    6. Ulas G, Lemmin T, Wu Y, Gassner GT, DeGrado WF. Designed metalloprotein stabilizes a semiquinone radical. Nat Chem. 2016 Apr; 8(4):354-9. PMID: 27001731.
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    7. Gorman J, Soto C, Yang MM, Davenport TM, Guttman M, Bailer RT, Chambers M, Chuang GY, DeKosky BJ, Doria-Rose NA, Druz A, Ernandes MJ, Georgiev IS, Jarosinski MC, Joyce MG, Lemmin T, Leung S, Louder MK, McDaniel JR, Narpala S, Pancera M, Stuckey J, Wu X, Yang Y, Zhang B, Zhou T, Program NC, Mullikin JC, Baxa U, Georgiou G, McDermott AB, Bonsignori M, Haynes BF, Moore PL, Morris L, Lee KK, Shapiro L, Mascola JR, Kwong PD. Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat Struct Mol Biol. 2016 Jan; 23(1):81-90. PMID: 26689967.
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    8. Bovigny C, Tamò G, Lemmin T, Maïno N, Dal Peraro M. LipidBuilder: A Framework To Build Realistic Models for Biological Membranes. J Chem Inf Model. 2015 Dec 28; 55(12):2491-9. PMID: 26606666.
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    9. Saita E, Abriata LA, Tsai YT, Trajtenberg F, Lemmin T, Buschiazzo A, Dal Peraro M, de Mendoza D, Albanesi D. A coiled coil switch mediates cold sensing by the thermosensory protein DesK. Mol Microbiol. 2015 Oct; 98(2):258-71. PMID: 26172072.
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    10. Vestergaard AL, Coleman JA, Lemmin T, Mikkelsen SA, Molday LL, Vilsen B, Molday RS, Dal Peraro M, Andersen JP. Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2. Proc Natl Acad Sci U S A. 2014 Apr 8; 111(14):E1334-43. PMID: 24706822; PMCID: PMC3986137.
    11. Lemmin T, Dimitrov M, Fraering PC, Dal Peraro M. Perturbations of the straight transmembrane a-helical structure of the amyloid precursor protein affect its processing by ?-secretase. J Biol Chem. 2014 Mar 7; 289(10):6763-74. PMID: 24469457; PMCID: PMC3945338.
    12. Yan SE, Lemmin T, Salvi S, Lausch E, Superti-Furga A, Rokicki D, Dal Peraro M, van der Goot FG. In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy. Hum Mutat. 2013 Jul; 34(7):1005-17. PMID: 23554269.
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    13. Lemmin T, Soto CS, Clinthorne G, DeGrado WF, Dal Peraro M. Assembly of the transmembrane domain of E. coli PhoQ histidine kinase: implications for signal transduction from molecular simulations. PLoS Comput Biol. 2013; 9(1):e1002878. PMID: 23359663; PMCID: PMC3554529.
    14. Dimitrov M, Alattia JR, Lemmin T, Lehal R, Fligier A, Houacine J, Hussain I, Radtke F, Dal Peraro M, Beher D, Fraering PC. Alzheimer's disease mutations in APP but not ?-secretase modulators affect epsilon-cleavage-dependent AICD production. Nat Commun. 2013; 4:2246. PMID: 23907250.
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    15. Lemmin T, Bovigny C, Lançon D, Dal Peraro M. Cardiolipin Models for Molecular Simulations of Bacterial and Mitochondrial Membranes. J Chem Theory Comput. 2013 Jan 8; 9(1):670-8. PMID: 26589063.
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    16. Lakkaraju AK, Abrami L, Lemmin T, Blaskovic S, Kunz B, Kihara A, Dal Peraro M, van der Goot FG. Palmitoylated calnexin is a key component of the ribosome-translocon complex. EMBO J. 2012 Apr 4; 31(7):1823-35. PMID: 22314232; PMCID: PMC3321195.
    17. Lemmin T, Ganesh G, Gassert R, Burdet E, Kawato M, Haruno M. Model-based attenuation of movement artifacts in fMRI. J Neurosci Methods. 2010 Sep 30; 192(1):58-69. PMID: 20654648.
      View in: PubMed
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