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Thomas Lowe, MD

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
Address401 Parnassus Ave, LangPorter
San Francisco CA 94143
Phone415-476-9564
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    Title(s)UCSF Weill Institute for Neurosciences


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    Dr. Thomas L. Lowe is a child, adolescent and adult psychiatrist, clinical researcher and previous director (1983-2015) of the Tourette's and Tic Disorders Clinic at UCSF (TTDC).

    Individuals with clinical inquiries should contact Dr. Lowe at ttdcnorcal.com or (415) 275-4933.

    Dr. Lowe provides consultations to children, adolescents and adults, their families and health care providers about Tourette's & tic disorders, as well as psychotropic medications used to treat conditions such as obsessive-compulsive, attention-deficit, anxiety and movement disorders.

    Dr. Lowe earned a medical degree at the University of Michigan Medical School in Ann Arbor, MI. He completed a residency in psychiatry at the University of Rochester's Strong Memorial Hospital in New York and a fellowship in child and adolescent psychiatry at the Child Study Center at Yale University in New Haven, Connecticut. He then completed a post-doctoral fellowship at the Child Study Center in movement disorders and developmental disabilities, followed by a faculty position at Yale University. He was recruited to UCSF in 1983.

    He is a recently retired associate professor of psychiatry in the Division of Child and Adolescent Psychiatry at UCSF, on part-time recall to UCSF for research activities.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Long-Term Follow-up of Patients with Tourette Syndrome; doi:10-1002/mdc3.12696. Movement Disorders-Clinical Practice. 2019; 6(1-Jan):40-45. View Publication.
    2. Long-Term Follow-up of Patients with Tourette's Syndrome. Mov Disord Clin Pract. 2019 Jan; 6(1):40-45. Lowe TL, Capriotti MR, McBurnett K. PMID: 30746414.
      View in: PubMed   Mentions:
    3. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry. 2015 Jan; 172(1):82-93. Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, Arepalli S, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrió GB, Bienvenu OJ, Black DW, Bloch MH, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell DD, Cappi C, Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V, Cullen B, Cusi D, Delorme R, Denys D, Dion Y, Eapen V, Egberts K, Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gilbert DL, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Hardy J, Heiman GA, Hemmings SM, Herrera LD, Hezel DM, Hoekstra PJ, Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Lupoli S, Macciardi F, Maier W, Manunta P, Marconi M, McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Nurmi E, Ochoa WC, Ophoff RA, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosário MC, Rosenberg D, Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M, Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Weale M, Weiss R, Wendland JR, Westenberg HG, Shugart YY, Hounie AG, Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D, Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL, Conti DV, Arnold PD, Freimer NB, Stewart SE, Knowles JA, Cox NJ, Pauls DL. PMID: 25158072.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    4. Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. J Am Acad Child Adolesc Psychiatry. 2014 Aug; 53(8):910-9. McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM. PMID: 25062598.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    5. Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet. 2013 Oct; 9(10):e1003864. Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Cardona Silgado JC, Cath DC, Cavallini MC, Chavira DA, Chouinard S, Conti DV, Cook EH, Coric V, Cullen BA, Deforce D, Delorme R, Dion Y, Edlund CK, Egberts K, Falkai P, Fernandez TV, Gallagher PJ, Garrido H, Geller D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Haddad S, Heiman GA, Hemmings SM, Hounie AG, Illmann C, Jankovic J, Jenike MA, Kennedy JL, King RA, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Macciardi F, McCracken JT, McGrath LM, Mesa Restrepo SC, Moessner R, Morgan J, Muller H, Murphy DL, Naarden AL, Ochoa WC, Ophoff RA, Osiecki L, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner TJ, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosàrio MC, Rosenberg D, Rouleau GA, Ruhrmann S, Ruiz-Linares A, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Valencia Duarte AV, Vallada H, Van Nieuwerburgh F, Veenstra-Vanderweele J, Walitza S, Wang Y, Wendland JR, Westenberg HG, Shugart YY, Miguel EC, McMahon W, Wagner M, Nicolini H, Posthuma D, Hanna GL, Heutink P, Denys D, Arnold PD, Oostra BA, Nestadt G, Freimer NB, Pauls DL, Wray NR, Stewart SE, Mathews CA, Knowles JA, Cox NJ, Scharf JM. PMID: 24204291.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    6. CNV analysis in Tourette syndrome implicates large genomic rearrangements in COL8A1 and NRXN1. PLoS One. 2013; 8(3):e59061. Nag A, Bochukova EG, Kremeyer B, Campbell DD, Muller H, Valencia-Duarte AV, Cardona J, Rivas IC, Mesa SC, Cuartas M, Garcia J, Bedoya G, Cornejo W, Herrera LD, Romero R, Fournier E, Reus VI, Lowe TL, Farooqi IS, Mathews CA, McGrath LM, Yu D, Cook E, Wang K, Scharf JM, Pauls DL, Freimer NB, Plagnol V, Ruiz-Linares A. PMID: 23533600.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    7. Prevalence and clinical correlates of explosive outbursts in Tourette syndrome. Psychiatry Res. 2013 Feb 28; 205(3):269-75. Chen K, Budman CL, Diego Herrera L, Witkin JE, Weiss NT, Lowe TL, Freimer NB, Reus VI, Mathews CA. PMID: 23040794.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. Genome-wide association study of Tourette's syndrome. Mol Psychiatry. 2013 Jun; 18(6):721-8. Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrío GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A, Hardy J, Strengman E, Ophoff RA, Wagner M, Moessner R, Mirel DB, Posthuma D, Sabatti C, Eskin E, Conti DV, Knowles JA, Ruiz-Linares A, Rouleau GA, Purcell S, Heutink P, Oostra BA, McMahon WM, Freimer NB, Cox NJ, Pauls DL. PMID: 22889924.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    9. Serial immune markers do not correlate with clinical exacerbations in pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections. Pediatrics. 2008 Jun; 121(6):1198-205. Singer HS, Gause C, Morris C, Lopez P. PMID: 18519490.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    10. Streptococcal infection and exacerbations of childhood tics and obsessive-compulsive symptoms: a prospective blinded cohort study. Pediatrics. 2008 Jun; 121(6):1188-97. Kurlan R, Johnson D, Kaplan EL. PMID: 18519489.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    11. Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses. Hum Mol Genet. 2006 Nov 15; 15(22):3324-8. Keen-Kim D, Mathews CA, Reus VI, Lowe TL, Herrera LD, Budman CL, Gross-Tsur V, Pulver AE, Bruun RD, Erenberg G, Naarden A, Sabatti C, Freimer NB. PMID: 17035247.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    12. Association between maternal smoking and increased symptom severity in Tourette's syndrome. Am J Psychiatry. 2006 Jun; 163(6):1066-73. Mathews CA, Bimson B, Lowe TL, Herrera LD, Budman CL, Erenberg G, Naarden A, Bruun RD, Freimer NB, Reus VI. PMID: 16741208.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    13. Tic symptom profiles in subjects with Tourette Syndrome from two genetically isolated populations. Biol Psychiatry. 2007 Feb 01; 61(3):292-300. Mathews CA, Jang KL, Herrera LD, Lowe TL, Budman CL, Erenberg G, Naarden A, Bruun RD, Schork NJ, Freimer NB, Reus VI. PMID: 16581034.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    14. Regarding "antibiotic prophylaxis with azithromycin or penicillin for childhood-onset neuropsychiatric disorders". Biol Psychiatry. 2005 Dec 01; 58(11):917; author reply 918-9. Budman C, Coffey B, Dure L, Gilbert D, Juncos J, Kaplan E, King R, Kurlan R, Lowe T, Mack K, Mink J, Schlaggar B, Singer H. PMID: 16242121.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Self injurious behaviour in Tourette syndrome: correlates with impulsivity and impulse control. J Neurol Neurosurg Psychiatry. 2004 Aug; 75(8):1149-55. Mathews CA, Waller J, Glidden D, Lowe TL, Herrera LD, Budman CL, Erenberg G, Naarden A, Bruun RD, Freimer NB, Reus VI. PMID: 15258218.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    16. Genetic studies of neuropsychiatric disorders in Costa Rica: a model for the use of isolated populations. Psychiatr Genet. 2004 Mar; 14(1):13-23. Mathews CA, Reus VI, Bejarano J, Escamilla MA, Fournier E, Herrera LD, Lowe TL, McInnes LA, Molina J, Ophoff RA, Raventos H, Sandkuijl LA, Service SK, Spesny M, León PE, Freimer NB. PMID: 15091311.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    17. Cultural influences on diagnosis and perception of Tourette syndrome in Costa Rica. J Am Acad Child Adolesc Psychiatry. 2001 Apr; 40(4):456-63. Mathews CA, Herrera Amighetti LD, Lowe TL, van de Wetering BJ, Freimer NB, Reus VI. PMID: 11314572.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Amer J Med Genetics Neuropsych Genetics. Population Genetic Mapping of Tourette Syndrome. 1997; (74):659. Mathews, CA, DeMille, MMC, Herrera, LD, Reus, VI, Lowe, TL.
    19. Amer J of Human Genetics. Population Mapping of Tourette Syndrome. 1997; (61):A401. Mathews, CA, DeMille, MMC, Herrera, LD, Reus, VI, Lowe, TL.
    20. Anomalous kinetic visual fields found in family members of patients with a confirmed diagnosis of Gilles de la Tourette syndrome. Optom Vis Sci. 1991 Oct; 68(10):807-12. Enoch JM, Lakshminarayanan V, Itzhaki A, Khamar BM, Landau K, Lowe T, Surendran T, Comerford J. PMID: 1749602.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Temporal steps in the visual field in neuropsychiatric disorders. Lancet. 1989 Nov 25; 2(8674):1283-4. Khamar BM, Enoch JM, Lowe T, Schrier H. PMID: 2573802.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Perimetry Update 1988/89. Anomalous kinetic visual fields in Gilles de la Tourette Syndrome patients and family members. 1989; 77-84. Enoch, JM, Itzhaki, A, Lowe, TL.
    23. Neuro-Opthalmology. Gille de la Tourette Syndrome: Visual Effects. 1988; 5(8):251-257. Enoch, JM, Itzhaki, A, Lowe, TL.
    24. Neuro-Ophthalmology. Gilles de la Tourette Syndrome: Genetic marker?. 1988; 5(8):259-265. Enoch, JM, Itzhaki, A, Lowe, TL.
    25. Depressed mood during pregnancy and the puerperium: clinical recognition and implications for clinical practice. Am J Psychiatry. 1985 Jun; 142(6):728-31. Saks BR, Frank JB, Lowe TL, Berman W, Naftolin F, Cohen DJ. PMID: 4003593.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Stimulant medications precipitate Tourette's syndrome. JAMA. 1982 Mar 26; 247(12):1729-31. Lowe TL, Cohen DJ, Detlor J, Kremenitzer MW, Shaywitz BA. PMID: 6950128.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    27. Stimulant medications precipitate Tourette's syndrome. JAMA. 1982 Feb 26; 247(8):1168-9. Lowe TL, Cohen DJ, Detlor J, Kremenitzer MW, Shaywitz BA. PMID: 6120250.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    28. Pediatric Research. Oral clonidine as a test for growth hormone in short stature and Tourette's Syndrome. 1981; (15):508. Gertner, J, Lowe, TL, Genel, M, Young, G, Cohen, D.
    29. J Amer Acad Child Psychiatry. Assessing psychopathology in children of psychiatrically disturbed parents: A pilot study. 1981; (20):112-122. Orvashel, H, Weissman, MM, Padin, N, Lowe, TL.
    30. J Amer Acad Child Psychiatry. Folic acid and B-12 in autism and neuropsychiatric disturbances of childhood. 1981; (20):104=111. Lowe, TL, Cohen, DJ, Miller, S, Young, JG.
    31. J Autism and Developmental Disorders. Thyroid hormone in autistic children. 1980; 4(10):445-450. Cohen, DJ, Young, JG, Lowe, TL, Harcherik, D.
    32. Digest of Neurology and Psychiatry. Detection of phenylketonuria in autistic and psychotic children. 1980; (February):87. Lowe, TL, Tanaka, K, Seashore, MJ, Cohen, DJ.
    33. JAMA. Detection of phenylketonuria in autistic and psychotic children. 1980; 2(243):126-128. Lowe, TL, Tanaka, K, Seashore, MJ, Young, JG, Cohen, DJ.
    34. Clinical Chemistry. A gas chromatographic method for analysis of urinary organic acids. II. Description of the procedure and its application to the diagnosis of patients with organic acidurias. 1980; 13(26):1847-1853. Tanaka, K, West-Dull, A, Hine, DG, Lynn, TG, Lowe, TL.
    35. J of Infectious Diseases. Quantitation of neisseria gonorrhoeae from women with gonorrhea. 1976; (133):612-626. Lowe, TL, Kraus, SJ.
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