Todd McDevitt, PhD

Title(s)Professor, Bioengineering
SchoolSchool of Pharmacy
Address1650 Owens Street
San Francisco 94158
ORCID ORCID Icon0000-0002-8905-4931 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of WashingtonPh.D.2001Bioengineering
    Duke UniversityB.S.E.1997Biomedical & Electrical Engineering
    Collapse Awards and Honors
    California Institute for Regenerative Medicine2014  - 2019Research Leadership Award
    American Institute of Medical & Biological Engineering2014College of Fellows
    Georgia Trend magazine2013“40 Under 40”
    Georgia Institute of Technology2013  - 2014Carol Ann and David D. Flanagan Professorship
    Georgia Tech Biomedical Engineering Society2011“Above & Beyond” (Eagle) Award
    Society for Biomaterials2010Young Investigator Award
    Georgia Institute of Technology2010Junior Faculty Outstanding Undergraduate Research Mentor
    Petit Institute for Bioengineering and Bioscience (Georgia Tech)2009  - 2014Petit Faculty Fellow
    American Heart Association, Council on Basic Cardiovascular Sciences2004New Investigator Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Defining Strategies to Target Energy Failure in Metabolically Vulnerable Human Cells
    NIH/NIA R01AG065428Aug 1, 2020 - Apr 30, 2025
    Role: Co-Principal Investigator
    Human microtissues for in situ detection and functional measurement of adverse consequences caused by genome editing
    NIH/NIBIB U01EB029374Sep 25, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Human microtissues for in situ detection and functional measurement of adverse consequences caused by genome editing
    NIH/NIEHS U01ES032673Sep 25, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Human microtissues for in situ detection and functional measurement of adverse consequences caused by genome editing
    NIH/NHLBI U01HL145795Sep 25, 2018 - Jun 30, 2023
    Role: Principal Investigator
    An Engineering Research Center for Cell Manufacturing Technologies (CMaT)
    Georgia Tech/NSF NSF1648035Oct 1, 2017 - Sep 30, 2022
    Role: Co-Investigator
    Alliance for Regenerative Rehabilitation Research & Training (AR3T)
    NIH P2CHD086843Sep 17, 2015 - Jun 30, 2020
    Role: Co-Investigator
    Role Description: Subcontract via University of Pittsburgh. Project titled: Mechanical conditioning of stem cell microtissue contructs.
    Stem Cell Morphogen Delivery via Engineered Biomaterials
    NIH/NIAMS R01AR062006May 1, 2015 - Aug 31, 2016
    Role: Principal Investigator
    Engineering microscale tissue constructs from human pluripotent stem cells
    CIRM LA1-C14-08015Dec 1, 2014 - Nov 30, 2019
    Role: Principal Investigator
    Engineering Mesenchymal Stem Cell Microenvironments to Promote Immunomodulation
    NIH/NIAID R21AI109499Aug 1, 2014 - Jul 31, 2016
    Role: Principal Investigator
    Tailorable Glycosaminoglycans for Enhanced Stem Cell Chondrogenesis
    NSF DMR1207045Jul 1, 2012 - Jun 30, 2015
    Role: Co-Investigator
    Emerging Behaviors of Integrated Cellular Systems (EBICS)
    MIT/NSF CBET0939511Sep 15, 2010 - Aug 31, 2020
    Role: Co-Investigator
    STC: Emergent Behaviors of Integrated Cellular Systems
    NSF STC CBET0939511Sep 15, 2010 - Aug 31, 2015
    Role: Co-Investigator
    IGERT: Stem Cell Biomaufactuing
    NSF IGERT DGE 0965945Aug 15, 2010 - Jul 31, 2015
    Role: Co-Investigator
    Microfluidic perfusion control of embryonic stem cell differentiation
    NIH/NIBIB R01EB010061Mar 1, 2010 - Feb 28, 2014
    Role: Principal Investigator
    Microsphere-mediated differentiation of embryonic stem cells
    NIH/NIGMS R01GM088291Aug 1, 2009 - Jul 31, 2014
    Role: Principal Investigator
    Regenerative acellular biomaterials derived from embryonic stem cells
    NIH/NIBIB R21EB007316Sep 1, 2007 - Aug 31, 2010
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients. bioRxiv. 2020 Sep 12. Pérez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Ramadoss GN, Silva AC, Flanigan WR, Li H, Nakamura K, Whitman JD, Ott M, Conklin BR, McDevitt TC. PMID: 32935097.
      View in: PubMed   Mentions:
    2. Microfluidic perfusion modulates growth and motor neuron differentiation of stem cell aggregates. Analyst. 2020 Jul 21; 145(14):4815-4826. Jackson-Holmes EL, Schaefer AW, McDevitt TC, Lu H. PMID: 32515433.
      View in: PubMed   Mentions:    Fields:    
    3. Single-Cell Determination of Cardiac Microtissue Structure and Function Using Light Sheet Microscopy. Tissue Eng Part C Methods. 2020 04; 26(4):207-215. Turaga D, Matthys OB, Hookway TA, Joy DA, Calvert M, McDevitt TC. PMID: 32111148.
      View in: PubMed   Mentions:    Fields:    
    4. Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration. Sci Adv. 2020 01; 6(1):eaay1240. Hettiaratchi MH, Krishnan L, Rouse T, Chou C, McDevitt TC, Guldberg RE. PMID: 31922007.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    5. Author Correction: V2a interneuron differentiation from mouse and human pluripotent stem cells. Nat Protoc. 2020 Jan; 15(1):181. Butts JC, Iyer N, White N, Thompson R, Sakiyama-Elbert S, McDevitt TC. PMID: 31705126.
      View in: PubMed   Mentions:    Fields:    
    6. Automated Single Cell Tracking of In Vitro Multi-Cellular Morphogenesis Predicts Pluripotent Stem Cell Fate Decisions. J Biomol Tech. 2019 Dec; 30(Suppl):S6. Joy D, Libby A, McDevitt T. PMID: 31892872.
      View in: PubMed   Mentions:
    7. Automated Design of Pluripotent Stem Cell Self-Organization. Cell Syst. 2019 11 27; 9(5):483-495.e10. Libby ARG, Briers D, Haghighi I, Joy DA, Conklin BR, Belta C, McDevitt TC. PMID: 31759947.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. V2a interneuron differentiation from mouse and human pluripotent stem cells. Nat Protoc. 2019 11; 14(11):3033-3058. Butts JC, Iyer N, White N, Thompson R, Sakiyama-Elbert S, McDevitt TC. PMID: 31628445.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Imaging the developing human external and internal urogenital organs with light sheet fluorescence microscopy. Differentiation. 2020 Jan - Feb; 111:12-21. Isaacson D, McCreedy D, Calvert M, Shen J, Sinclair A, Cao M, Li Y, McDevitt T, Cunha G, Baskin L. PMID: 31634681.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Hyaluronic acid as a macromolecular crowding agent for production of cell-derived matrices. Acta Biomater. 2019 12; 100:292-305. Shendi D, Marzi J, Linthicum W, Rickards AJ, Dolivo DM, Keller S, Kauss MA, Wen Q, McDevitt TC, Dominko T, Schenke-Layland K, Rolle MW. PMID: 31568877.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. Phenotypic Variation Between Stromal Cells Differentially Impacts Engineered Cardiac Tissue Function. Tissue Eng Part A. 2019 05; 25(9-10):773-785. Hookway TA, Matthys OB, Mendoza-Camacho FN, Rains S, Sepulveda JE, Joy DA, McDevitt TC. PMID: 30968748.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Comparable Decellularization of Fetal and Adult Cardiac Tissue Explants as 3D-like Platforms for In Vitro Studies. J Vis Exp. 2019 03 21; (145). Silva AC, Oliveira MJ, McDevitt TC, Barbosa MA, Nascimento DS, Pinto-do-Ó P. PMID: 30958455.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Author Correction: Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment. Nat Commun. 2018 11 16; 9(1):4901. Glen CM, McDevitt TC, Kemp ML. PMID: 30446658.
      View in: PubMed   Mentions:    Fields:    
    14. Perspective: The promise of multi-cellular engineered living systems. APL Bioeng. 2018 Dec; 2(4):040901. Kamm RD, Bashir R, Arora N, Dar RD, Gillette MU, Griffith LG, Kemp ML, Kinlaw K, Levin M, Martin AC, McDevitt TC, Nerem RM, Powers MJ, Saif TA, Sharpe J, Takayama S, Takeuchi S, Weiss R, Ye K, Yevick HG, Zaman MH. PMID: 31069321.
      View in: PubMed   Mentions:
    15. Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. Elife. 2018 10 09; 7. Libby AR, Joy DA, So PL, Mandegar MA, Muncie JM, Mendoza-Camacho FN, Weaver VM, Conklin BR, McDevitt TC. PMID: 30298816.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment. Nat Commun. 2018 10 05; 9(1):4111. Glen CM, McDevitt TC, Kemp ML. PMID: 30291250.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    17. Three-dimensional imaging of the developing human fetal urogenital-genital tract: Indifferent stage to male and female differentiation. Differentiation. 2018 Sep - Oct; 103:14-23. Isaacson D, Shen J, Overland M, Li Y, Sinclair A, Cao M, McCreedy D, Calvert M, McDevitt T, Cunha GR, Baskin L. PMID: 30262218.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. A rapid method for determining protein diffusion through hydrogels for regenerative medicine applications. APL Bioeng. 2018 Jun; 2(2):026110. Hettiaratchi MH, Schudel A, Rouse T, García AJ, Thomas SN, Guldberg RE, McDevitt TC. PMID: 31069307.
      View in: PubMed   Mentions:
    19. 313 Engineering the 3D MSC Spheroid Microenvironment to Enhance Immunomodulation. Cytotherapy. 2018 May 1; 20(5):s106. J. Zimmermann, T.C. McDevitt. .
      View in: Publisher Site   Mentions:
    20. Biophysical subsets of embryonic stem cells display distinct phenotypic and morphological signatures. PLoS One. 2018; 13(3):e0192631. Bongiorno T, Gura J, Talwar P, Chambers D, Young KM, Arafat D, Wang G, Jackson-Holmes EL, Qiu P, McDevitt TC, Sulchek T. PMID: 29518080.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Lightsheet fluorescence microscopy of branching human fetal kidney. Kidney Int. 2018 02; 93(2):525. Isaacson D, Shen J, McCreedy D, Calvert M, McDevitt T, Cunha G, Baskin L. PMID: 29389399.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Microparticle-mediated sequestration of cell-secreted proteins to modulate chondrocytic differentiation. Acta Biomater. 2018 03 01; 68:125-136. Rinker TE, Philbrick BD, Hettiaratchi MH, Smalley DM, McDevitt TC, Temenoff JS. PMID: 29292168.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Functionalization of microparticles with mineral coatings enhances non-viral transfection of primary human cells. Sci Rep. 2017 10 27; 7(1):14211. Khalil AS, Yu X, Xie AW, Fontana G, Umhoefer JM, Johnson HJ, Hookway TA, McDevitt TC, Murphy WL. PMID: 29079806.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    24. A microfluidic trap array for longitudinal monitoring and multi-modal phenotypic analysis of individual stem cell aggregates. Lab Chip. 2017 10 25; 17(21):3634-3642. Jackson-Holmes EL, McDevitt TC, Lu H. PMID: 28952622.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    25. Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes. J Biotechnol. 2017 Nov 20; 262:28-39. Costa MHG, McDevitt TC, Cabral JMS, da Silva CL, Ferreira FC. PMID: 28965974.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    26. Enhanced in vivo retention of low dose BMP-2 via heparin microparticle delivery does not accelerate bone healing in a critically sized femoral defect. Acta Biomater. 2017 09 01; 59:21-32. Hettiaratchi MH, Rouse T, Chou C, Krishnan L, Stevens HY, Li MA, McDevitt TC, Guldberg RE. PMID: 28645809.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    27. The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids. J Biomech. 2017 07 05; 59:71-79. Griffin FE, Schiavi J, McDevitt TC, McGarry JP, McNamara LM. PMID: 28577903.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    28. Differentiation of V2a interneurons from human pluripotent stem cells. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):4969-4974. Butts JC, McCreedy DA, Martinez-Vargas JA, Mendoza-Camacho FN, Hookway TA, Gifford CA, Taneja P, Noble-Haeusslein L, McDevitt TC. PMID: 28438991.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    29. Competitive Protein Binding Influences Heparin-Based Modulation of Spatial Growth Factor Delivery for Bone Regeneration. Tissue Eng Part A. 2017 07; 23(13-14):683-695. Hettiaratchi MH, Chou C, Servies N, Smeekens JM, Cheng A, Esancy C, Wu R, McDevitt TC, Guldberg RE, Krishnan L. PMID: 28338419.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. Enhanced Immunosuppression of T Cells by Sustained Presentation of Bioactive Interferon-? Within Three-Dimensional Mesenchymal Stem Cell Constructs. Stem Cells Translational Medicine. 2017 Jan 1; 6(1):223-237. Joshua A. Zimmermann, Marian H. Hettiaratchi, Todd C. McDevitt. .
      View in: Publisher Site   Mentions:
    31. Environmental manipulation to promote stem cell survival in vivo: use of aggregation, oxygen carrier, and BMP-2 co-delivery strategies. J Mater Chem B. 2016 May 28; 4(20):3594-3607. Allen AB, Zimmermann JA, Burnsed OA, Yakubovich DC, Stevens HY, Gazit Z, McDevitt TC, Guldberg RE. PMID: 32263389.
      View in: PubMed   Mentions:    Fields:    
    32. Biomaterial strategies for controlling stem cell fate via morphogen sequestration. J Mater Chem B. 2016 May 28; 4(20):3464-3481. Hettiaratchi MH, Guldberg RE, McDevitt TC. PMID: 32263380.
      View in: PubMed   Mentions:    Fields:    
    33. Expansion and angiogenic potential of mesenchymal stem cells from patients with critical limb ischemia. J Vasc Surg. 2017 Mar; 65(3):826-838.e1. Brewster L, Robinson S, Wang R, Griffiths S, Li H, Peister A, Copland I, McDevitt T. PMID: 26921003.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    34. Design Principles for Engineering of Tissues from Human Pluripotent Stem Cells. Curr Stem Cell Rep. 2016 Mar; 2(1):43-51. Matthys OB, Hookway TA, McDevitt TC. PMID: 27330934.
      View in: PubMed   Mentions:
    35. A Multi-Modality CMOS Sensor Array for Cell-Based Assay and Drug Screening. IEEE Trans Biomed Circuits Syst. 2015 Dec; 9(6):801-14. Chi T, Park JS, Butts JC, Hookway TA, Su A, Zhu C, Styczynski MP, McDevitt TC, Wang H. PMID: 26812735.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    36. Biomaterial strategies for controlling stem cell fate via morphogen sequestration. Journal of Materials Chemistry B. 2016 Jan 1; 4(20):3464-3481. M. H. Hettiaratchi, R. E. Guldberg, T. C. McDevitt. .
      View in: Publisher Site   Mentions:
    37. Environmental manipulation to promote stem cell survival in vivo : use of aggregation, oxygen carrier, and BMP-2 co-delivery strategies. Journal of Materials Chemistry B. 2016 Jan 1; 4(20):3594-3607. Ashley B. Allen, Josh A. Zimmermann, Olivia A. Burnsed, Doron Cohn Yakubovich, Hazel Y. Stevens, Zulma Gazit, Todd C. McDevitt, Robert E. Guldberg. .
      View in: Publisher Site   Mentions:
    38. Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny. Methods. 2016 05 15; 101:11-20. Hookway TA, Butts JC, Lee E, Tang H, McDevitt TC. PMID: 26658353.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    39. Mineral particles modulate osteo-chondrogenic differentiation of embryonic stem cell aggregates. Acta Biomater. 2016 Jan; 29:42-51. Wang Y, Yu X, Baker C, Murphy WL, McDevitt TC. PMID: 26597546.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    40. MMP-mediated mesenchymal morphogenesis of pluripotent stem cell aggregates stimulated by gelatin methacrylate microparticle incorporation. Biomaterials. 2016 Jan; 76:66-75. Nguyen AH, Wang Y, White DE, Platt MO, McDevitt TC. PMID: 26519649.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    41. Hydrolysis and Sulfation Pattern Effects on Release of Bioactive Bone Morphogenetic Protein-2 from Heparin-Based Microparticles. J Mater Chem B. 2015 Oct 28; 3(40):8001-8009. Tellier LE, Miller T, McDevitt TC, Temenoff JS. PMID: 27785363.
      View in: PubMed   Mentions: 5     Fields:    
    42. Quantitative multivariate analysis of dynamic multicellular morphogenic trajectories. Integr Biol (Camb). 2015 Jul; 7(7):825-33. White DE, Sylvester JB, Levario TJ, Lu H, Streelman JT, McDevitt TC, Kemp ML. PMID: 26095427.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    43. Osteogenic embryoid body-derived material induces bone formation in vivo. Sci Rep. 2015 May 11; 5:9960. Sutha K, Schwartz Z, Wang Y, Hyzy S, Boyan BD, McDevitt TC. PMID: 25961152.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    44. Phenotypic analysis of familial breast cancer: comparison of BRCAx tumors with BRCA1-, BRCA2-carriers and non-familial breast cancer. Eur J Surg Oncol. 2015 May; 41(5):641-6. Aloraifi F, Alshehhi M, McDevitt T, Cody N, Meany M, O'Doherty A, Quinn CM, Green AJ, Bracken A, Geraghty JG. PMID: 25736863.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Cell-derived matrices for tissue engineering and regenerative medicine applications. Biomater Sci. 2015 Jan; 3(1):12-24. Fitzpatrick LE, McDevitt TC. PMID: 25530850.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    46. Differential expression of extracellular matrix and growth factors by embryoid bodies in hydrodynamic and static cultures. Tissue Eng Part C Methods. 2014 Dec; 20(12):931-40. Fridley KM, Nair R, McDevitt TC. PMID: 25423310.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    47. Gelatin methacrylate microspheres for controlled growth factor release. Acta Biomater. 2015 Feb; 13:101-10. Nguyen AH, McKinney J, Miller T, Bongiorno T, McDevitt TC. PMID: 25463489.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    48. Chondroitin sulfate microparticles modulate transforming growth factor-ß1-induced chondrogenesis of human mesenchymal stem cell spheroids. Cells Tissues Organs. 2014; 199(2-3):117-30. Goude MC, McDevitt TC, Temenoff JS. PMID: 25413333.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    49. Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells. Stem Cell Reports. 2014 Aug 12; 3(2):260-8. Nguyen DC, Hookway TA, Wu Q, Jha R, Preininger MK, Chen X, Easley CA, Spearman P, Deshpande SR, Maher K, Wagner MB, McDevitt TC, Xu C. PMID: 25254340.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    50. Erratum: Materials as stem cell regulators. Nature Materials. 2014 Jul 1; 13(7):756-756. William L. Murphy, Todd C. McDevitt, Adam J. Engler. .
      View in: Publisher Site   Mentions:
    51. Materials as stem cell regulators. Nat Mater. 2014 Jun; 13(6):547-57. Murphy WL, McDevitt TC, Engler AJ. PMID: 24845994.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansAnimalsCells
    52. Heparin microparticle effects on presentation and bioactivity of bone morphogenetic protein-2. Biomaterials. 2014 Aug; 35(25):7228-38. Hettiaratchi MH, Miller T, Temenoff JS, Guldberg RE, McDevitt TC. PMID: 24881028.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    53. Structural and Biological Comparison of Cryopreserved and Fresh Amniotic Membrane Tissues. Journal of Biomaterials and Tissue Engineering. 2014 May 1; 4(5):379-388. Ek Kia Tan, Marissa Cooke, Christian Mandrycky, Megha Mahabole, Hua He, Julie O'Connell, Todd C. McDevitt, Scheffer C. G. Tseng. .
      View in: Publisher Site   Mentions:
    54. Mesenchymal morphogenesis of embryonic stem cells dynamically modulates the biophysical microtissue niche. Sci Rep. 2014 Mar 06; 4:4290. Kinney MA, Saeed R, McDevitt TC. PMID: 24598818.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    55. A global assessment of stem cell engineering. Tissue Eng Part A. 2014 Oct; 20(19-20):2575-89. Loring JF, McDevitt TC, Palecek SP, Schaffer DV, Zandstra PW, Nerem RM. PMID: 24428577.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    56. Soluble factors secreted by differentiating embryonic stem cells stimulate exogenous cell proliferation and migration. Stem Cell Res Ther. 2014 Feb 24; 5(1):26. Ngangan AV, Waring JC, Cooke MT, Mandrycky CJ, McDevitt TC. PMID: 24564947.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    57. Single-cell analysis of embryoid body heterogeneity using microfluidic trapping array. Biomed Microdevices. 2014 Feb; 16(1):79-90. Wilson JL, Suri S, Singh A, Rivet CA, Lu H, McDevitt TC. PMID: 24085533.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    58. Fluid shear stress pre-conditioning promotes endothelial morphogenesis of embryonic stem cells within embryoid bodies. Tissue Eng Part A. 2014 Mar; 20(5-6):954-65. Nsiah BA, Ahsan T, Griffiths S, Cooke M, Nerem RM, McDevitt TC. PMID: 24138406.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    59. Stem Cell Bioprocessing and Biomanufacturing. Stem Cell Engineering. 2014 Jan 1; 99-117. Todd C. McDevitt. .
      View in: Publisher Site   Mentions:
    60. Scalable culture of human pluripotent stem cells in 3D. Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52):20852-3. McDevitt TC. PMID: 24327732.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    61. Microfluidic-based patterning of embryonic stem cells for in vitro development studies. Lab Chip. 2013 Dec 07; 13(23):4617-24. Suri S, Singh A, Nguyen AH, Bratt-Leal AM, McDevitt TC, Lu H. PMID: 24113509.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    62. Engineering three-dimensional stem cell morphogenesis for the development of tissue models and scalable regenerative therapeutics. Ann Biomed Eng. 2014 Feb; 42(2):352-67. Kinney MA, Hookway TA, Wang Y, McDevitt TC. PMID: 24297495.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    63. Mechanical stiffness as an improved single-cell indicator of osteoblastic human mesenchymal stem cell differentiation. J Biomech. 2014 Jun 27; 47(9):2197-204. Bongiorno T, Kazlow J, Mezencev R, Griffiths S, Olivares-Navarrete R, McDonald JF, Schwartz Z, Boyan BD, McDevitt TC, Sulchek T. PMID: 24296276.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    64. Pre-conditioning mesenchymal stromal cell spheroids for immunomodulatory paracrine factor secretion. Cytotherapy. 2014 Mar; 16(3):331-45. Zimmermann JA, McDevitt TC. PMID: 24219905.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    65. Alginate encapsulation parameters influence the differentiation of microencapsulated embryonic stem cell aggregates. Biotechnol Bioeng. 2014 Mar; 111(3):618-31. Wilson JL, Najia MA, Saeed R, McDevitt TC. PMID: 24166004.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    66. Engineering the emergence of stem cell therapeutics. Sci Transl Med. 2013 Oct 16; 5(207):207ed17. Healy KE, McDevitt TC, Murphy WL, Nerem RM. PMID: 24132634.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    67. Molecular engineering of glycosaminoglycan chemistry for biomolecule delivery. Acta Biomater. 2014 Apr; 10(4):1705-19. Miller T, Goude MC, McDevitt TC, Temenoff JS. PMID: 24121191.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    68. Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro. Cytotherapy. 2013 Dec; 15(12):1469-83. Griffiths S, Baraniak PR, Copland IB, Nerem RM, McDevitt TC. PMID: 23981539.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    69. Familial breast cancer genetic testing in the West of Ireland. Ir J Med Sci. 2014 Jun; 183(2):199-206. McVeigh TP, Irwin R, Cody N, Miller N, McDevitt T, Sweeney KJ, Green A, Kerin MJ. PMID: 23884708.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    70. A microparticle approach to morphogen delivery within pluripotent stem cell aggregates. Biomaterials. 2013 Oct; 34(30):7227-35. Bratt-Leal AM, Nguyen AH, Hammersmith KA, Singh A, McDevitt TC. PMID: 23827184.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    71. Temporal modulation of ß-catenin signaling by multicellular aggregation kinetics impacts embryonic stem cell cardiomyogenesis. Stem Cells Dev. 2013 Oct 01; 22(19):2665-77. Kinney MA, Sargent CY, McDevitt TC. PMID: 23767804.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    72. Architectural protein subclasses shape 3D organization of genomes during lineage commitment. Cell. 2013 Jun 06; 153(6):1281-95. Phillips-Cremins JE, Sauria ME, Sanyal A, Gerasimova TI, Lajoie BR, Bell JS, Ong CT, Hookway TA, Guo C, Sun Y, Bland MJ, Wagstaff W, Dalton S, McDevitt TC, Sen R, Dekker J, Taylor J, Corces VG. PMID: 23706625.
      View in: PubMed   Mentions: 376     Fields:    Translation:AnimalsCells
    73. Adhesion strength-based, label-free isolation of human pluripotent stem cells. Nat Methods. 2013 May; 10(5):438-44. Singh A, Suri S, Lee T, Chilton JM, Cooke MT, Chen W, Fu J, Stice SL, Lu H, McDevitt TC, García AJ. PMID: 23563795.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    74. Spatial pattern dynamics of 3D stem cell loss of pluripotency via rules-based computational modeling. PLoS Comput Biol. 2013; 9(3):e1002952. White DE, Kinney MA, McDevitt TC, Kemp ML. PMID: 23516345.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    75. Stem cell microencapsulation for phenotypic control, bioprocessing, and transplantation. Biotechnol Bioeng. 2013 Mar; 110(3):667-82. Wilson JL, McDevitt TC. PMID: 23239279.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    76. Chapter II.1.7 Stem Cells Key Concepts. Biomaterials Science. 2013 Jan 1; 487-495. Richard L. Carpenedo, Todd C. McDevitt. .
      View in: Publisher Site   Mentions:
    77. Pluripotent Stem Cells. Tissue Engineering. 2012 Dec 11; 1-26. John Fisher, Antonios Mikos, Joseph Bronzino, Donald Peterson, Todd McDevitt, Melissa Kinney. .
      View in: Publisher Site   Mentions:
    78. Emerging strategies for spatiotemporal control of stem cell fate and morphogenesis. Trends Biotechnol. 2013 Feb; 31(2):78-84. Kinney MA, McDevitt TC. PMID: 23219200.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    79. Hydrodynamic modulation of pluripotent stem cells. Stem Cell Res Ther. 2012 Nov 20; 3(6):45. Fridley KM, Kinney MA, McDevitt TC. PMID: 23168068.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    80. Gene expression signatures of extracellular matrix and growth factors during embryonic stem cell differentiation. PLoS One. 2012; 7(10):e42580. Nair R, Ngangan AV, Kemp ML, McDevitt TC. PMID: 23077480.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    81. Systematic analysis of embryonic stem cell differentiation in hydrodynamic environments with controlled embryoid body size. Integr Biol (Camb). 2012 Jun; 4(6):641-50. Kinney MA, Saeed R, McDevitt TC. PMID: 22609810.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    82. Histone h1 depletion impairs embryonic stem cell differentiation. PLoS Genet. 2012; 8(5):e1002691. Zhang Y, Cooke M, Panjwani S, Cao K, Krauth B, Ho PY, Medrzycki M, Berhe DT, Pan C, McDevitt TC, Fan Y. PMID: 22589736.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    83. Stiffening of human mesenchymal stem cell spheroid microenvironments induced by incorporation of gelatin microparticles. J Mech Behav Biomed Mater. 2012 Jul; 11:63-71. Baraniak PR, Cooke MT, Saeed R, Kinney MA, Fridley KM, McDevitt TC. PMID: 22658155.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    84. Osteogenic differentiation of stem cells alters vitamin D receptor expression. Stem Cells Dev. 2012 Jul 01; 21(10):1726-35. Olivares-Navarrete R, Sutha K, Hyzy SL, Hutton DL, Schwartz Z, McDevitt T, Boyan BD. PMID: 22034957.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    85. Systematic engineering of 3D pluripotent stem cell niches to guide blood development. Biomaterials. 2012 Feb; 33(5):1271-80. Purpura KA, Bratt-Leal AM, Hammersmith KA, McDevitt TC, Zandstra PW. PMID: 22079776.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    86. Magnetic manipulation and spatial patterning of multi-cellular stem cell aggregates. Integr Biol (Camb). 2011 Dec; 3(12):1224-32. Bratt-Leal AM, Kepple KL, Carpenedo RL, Cooke MT, McDevitt TC. PMID: 22076329.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    87. Scaffold-free culture of mesenchymal stem cell spheroids in suspension preserves multilineage potential. Cell Tissue Res. 2012 Mar; 347(3):701-11. Baraniak PR, McDevitt TC. PMID: 21833761.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    88. The multiparametric effects of hydrodynamic environments on stem cell culture. Tissue Eng Part B Rev. 2011 Aug; 17(4):249-62. Kinney MA, Sargent CY, McDevitt TC. PMID: 21491967.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    89. Regenerating Function In Vivo with Myocytes Derived from Embryonic Stem Cells. Regenerating the Heart. 2011 Jan 1; 25-36. Priya R. Baraniak, Todd C. McDevitt. .
      View in: Publisher Site   Mentions:
    90. Development of nano- and microscale chondroitin sulfate particles for controlled growth factor delivery. Acta Biomater. 2011 Mar; 7(3):986-95. Lim JJ, Hammoudi TM, Bratt-Leal AM, Hamilton SK, Kepple KL, Bloodworth NC, McDevitt TC, Temenoff JS. PMID: 20965281.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    91. Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation. Biomaterials. 2011 Jan; 32(1):48-56. Bratt-Leal AM, Carpenedo RL, Ungrin MD, Zandstra PW, McDevitt TC. PMID: 20864164.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    92. Microsphere size effects on embryoid body incorporation and embryonic stem cell differentiation. J Biomed Mater Res A. 2010 Aug; 94(2):466-75. Carpenedo RL, Seaman SA, McDevitt TC. PMID: 20213812.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    93. Hydrodynamic modulation of embryonic stem cell differentiation by rotary orbital suspension culture. Biotechnol Bioeng. 2010 Feb 15; 105(3):611-26. Sargent CY, Berguig GY, Kinney MA, Hiatt LA, Carpenedo RL, Berson RE, McDevitt TC. PMID: 19816980.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    94. Stem cell paracrine actions and tissue regeneration. Regen Med. 2010 Jan; 5(1):121-43. Baraniak PR, McDevitt TC. PMID: 20017699.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansCells
    95. Integration of Biomaterials into 3D Stem Cell Microenvironments. Biomaterials as Stem Cell Niche. 2010 Jan 1; 2:45-59. Andres Bratt-Leal, Richard Carpenedo, Todd McDevitt. .
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    96. Synthesis and organization of hyaluronan and versican by embryonic stem cells undergoing embryoid body differentiation. J Histochem Cytochem. 2010 Apr; 58(4):345-58. Shukla S, Nair R, Rolle MW, Braun KR, Chan CK, Johnson PY, Wight TN, McDevitt TC. PMID: 20026669.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    97. Cardiomyogenic differentiation of embryoid bodies is promoted by rotary orbital suspension culture. Tissue Eng Part A. 2009 Feb; 15(2):331-42. Sargent CY, Berguig GY, McDevitt TC. PMID: 19193130.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    98. Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules. Biomaterials. 2009 May; 30(13):2507-15. Carpenedo RL, Bratt-Leal AM, Marklein RA, Seaman SA, Bowen NJ, McDonald JF, McDevitt TC. PMID: 19162317.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    99. Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation. Biotechnol Prog. 2009 Jan-Feb; 25(1):43-51. Bratt-Leal AM, Carpenedo RL, McDevitt TC. PMID: 19198003.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    100. Acellular matrices derived from differentiating embryonic stem cells. J Biomed Mater Res A. 2008 Dec 15; 87(4):1075-85. Nair R, Shukla S, McDevitt TC. PMID: 18260134.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    101. Acellularization of embryoid bodies via physical disruption methods. Biomaterials. 2009 Feb; 30(6):1143-9. Ngangan AV, McDevitt TC. PMID: 19042017.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    102. Innovation in the culture and derivation of pluripotent human stem cells. Curr Opin Biotechnol. 2008 Oct; 19(5):527-33. McDevitt TC, Palecek SP. PMID: 18760357.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    103. Efficacy of solvent extraction methods for acellularization of embryoid bodies. J Biomater Sci Polym Ed. 2008; 19(6):801-19. Nair R, Ngangan AV, McDevitt TC. PMID: 18534098.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    104. Engineering the 3D microenvironment of embryonic stem cells undergoing differentiation. Biomed Mater Eng. 2008; 18(4-5):179-81. McDevitt TC, Carpenedo RL, Sargent CY, Berguig GY, Marklein RA, Seaman S. PMID: 19065018.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    105. Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation. Stem Cells. 2007 Sep; 25(9):2224-34. Carpenedo RL, Sargent CY, McDevitt TC. PMID: 17585171.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    106. Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway. J Mol Cell Cardiol. 2005 Dec; 39(6):865-73. McDevitt TC, Laflamme MA, Murry CE. PMID: 16242146.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    107. Spatially organized layers of cardiomyocytes on biodegradable polyurethane films for myocardial repair. J Biomed Mater Res A. 2003 Sep 01; 66(3):586-95. McDevitt TC, Woodhouse KA, Hauschka SD, Murry CE, Stayton PS. PMID: 12918042.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsPHPublic Health
    108. Structural characterization and comparison of RGD cell-adhesion recognition sites engineered into streptavidin. Acta Crystallogr D Biol Crystallogr. 2003 May; 59(Pt 5):828-34. Le Trong I, McDevitt TC, Nelson KE, Stayton PS, Stenkamp RE. PMID: 12777798.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    109. In vitro generation of differentiated cardiac myofibers on micropatterned laminin surfaces. J Biomed Mater Res. 2002 Jun 05; 60(3):472-9. McDevitt TC, Angello JC, Whitney ML, Reinecke H, Hauschka SD, Murry CE, Stayton PS. PMID: 11920672.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    110. Micro-Scale Cell Patterning on Nonfouling Plasma Polymerized Tetraglyme Coatings by Protein Microcontact Printing. Plasmas and Polymers. 2002 Jun 1; 7(2):171-183. Y. Vickie Pan, Todd C. McDevitt, Tae Kyun Kim, Deborah Leach-Scampavia, Patrick S. Stayton, Denice D. Denton, Buddy D. Ratner. .
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    111. Quantitative interrogation of micropatterned biomolecules by surface force microscopy. Ultramicroscopy. 2000 Feb; 82(1-4):193-202. Garrison MD, McDevitt TC, Luginbühl R, Giachelli CM, Stayton P, Ratner BD. PMID: 10741670.
      View in: PubMed   Mentions: 1     Fields:    
    112. Smart and biofunctional streptavidin. Biomol Eng. 1999 Dec 31; 16(1-4):93-9. Stayton PS, Nelson KE, McDevitt TC, Bulmus V, Shimoboji T, Ding Z, Hoffman AS. PMID: 10796990.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    113. Constrained cell recognition peptides engineered into streptavidin. Biotechnol Prog. 1999 May-Jun; 15(3):391-6. McDevitt TC, Nelson KE, Stayton PS. PMID: 10356256.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
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