Loading...

Tomos Walters, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentMedicine
Address500 Parnassus Avenue
San Francisco CA 94117
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    The University of MelbourneMBBS (hons)2003Medicine and Surgery
    The University of MelbourneBMedSc2000Molecular virology
    The University of MelbournePhD2015Mechanisms of atrial fibrillation
    The Royal Melbourne Hospital, Melbourne, Australia2009Medical residency
    The Royal Melbourne Hospital, Melbourne, Australia2011Cardiology fellowship
    Princess Alexandra Hospital, Brisbane, Australia2012Electrophysiology fellowship
    The Royal Melbourne Hospital, Melbourne, Australia2015Electrophysiology fellowship
    UCSF2016Post-doctoral research fellowship
    UCSF2017Electrophysiology fellowship
    Collapse Awards and Honors
    12th Annual Interventional Symposium on Ventricular Arrhythmias2017Annual Mark E Josephson VT Innovation Award
    Heart Rhythm Society2017Heart Rhythm Journal Outstanding Publication Award (Clinical Research) for Young Electrophysiologist
    Cardiac Society of Australia and New Zealand2015Finalist in the Cardiac Society of Australia and New Zealand Ralph Reader competition for clinical r
    Heart Rhythm Society2015Kenneth M. Rosen Fellowship in Cardiac Pacing and Electrophysiology
    Melbourne Health and The Royal Melbourne Hospital2015Cleveland Young Investigator Award
    Asia Pacific Heart Rhythm Society Scientific Sessions2013Best Abstract
    The University of Melbourne2002Dean’s Honors List for Medicine
    The University of Melbourne2001Harold Attwood Prize for Clinical Pathology
    The University of Melbourne 2001Muriel Moody Prize for Clinical Communication
    The University of Melbourne 2000Thomas and Elizabeth Ross Scholarship for Clinical Research
    The University of Melbourne1998Sunderland Prize for Neuroscience

    Collapse Overview 
    Collapse Overview
    CLINICAL
    My particular clinical interest is the management of complex cardiac arrhythmias. I employ a patient-centered approach that seeks to understand how each individual patient experiences their heart rhythm disorder, and I work with each patient to develop a comprehensive management plan that address their particular concerns. With extensive training at leading centers in both Australia and the USA, I have particular expertise in catheter ablation of complex atrial and ventricular arrhythmias, and I also have expertise and great interest in the implantation and management of pacemakers, defibrillators and cardiac resynchronization devices.

    RESEARCH
    During my training in the management of heart rhythm disorders, I completed a PhD that focussed on the mechanisms underlying the persistence of atrial fibrillation, the most common sustained heart rhythm disorder encountered in clinical practice. I am now continuing this research, with the aim of identifying specific treatment targets in each individual patient with persistent atrial fibrillation. I am also heavily involved in research aimed at understanding the mechanisms through which ectopic heart beats from the ventricles of the heart can lead to heart failure, with the aim of developing therapies that might prevent heart failure.


    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Walters TE, Wick K, Tan G, Mearns M, Joseph SA, Morton JB, Sanders P, Bryant C, Kistler PM, Kalman JM. Symptom severity and quality of life in patients with atrial fibrillation: Psychological function outweighs clinical predictors. Int J Cardiol. 2018 Nov 02. PMID: 30442375.
      View in: PubMed
    2. Lee A, Walters TE, Gerstenfeld EP, Haqqani HM. Frequent Ventricular Ectopy: Implications and Outcomes. Heart Lung Circ. 2018 Oct 04. PMID: 30322758.
      View in: PubMed
    3. Walters TE, Wick K, Tan G, Mearns M, Joseph SA, Morton JB, Sanders P, Bryant C, Kistler PM, Kalman JM. Psychological Distress and Suicidal Ideation in Patients With Atrial Fibrillation: Prevalence and Response to Management Strategy. J Am Heart Assoc. 2018 Sep 18; 7(18):e005502. PMID: 30371197.
      View in: PubMed
    4. Szilágyi J, Walters TE, Marcus GM, Vedantham V, Moss JD, Badhwar N, Lee B, Lee R, Tseng ZH, Gerstenfeld EP. Surface ECG and intracardiac spectral measures predict atrial fibrillation recurrence after catheter ablation. J Cardiovasc Electrophysiol. 2018 Jul 17. PMID: 30016007.
      View in: PubMed
    5. Stacy R, Huttner K, Watts J, Peace J, Wirta D, Walters T, Sall K, Seaman J, Ni X, Prasanna G, Mogi M, Adams C, Yan JH, Wald M, He Y, Newton R, Kolega R, Grosskreutz C. A randomized, controlled phase I/II study to evaluate the safety and efficacy of MGV354 for ocular hypertension or glaucoma. Am J Ophthalmol. 2018 May 23. PMID: 29802818.
      View in: PubMed
    6. McLellan AJA, Prabhu S, Voskoboinik A, Wong MCG, Walters TE, Pathik B, Morris GM, Nisbet A, Lee G, Morton JB, Kalman JM, Kistler PM. Isolation of the posterior left atrium for patients with persistent atrial fibrillation: routine adenosine challenge for dormant posterior left atrial conduction improves long-term outcome. Europace. 2017 Dec 01; 19(12):1958-1966. PMID: 28204434.
      View in: PubMed
    7. Pathik B, Kalman JM, Walters T, Kuklik P, Zhao J, Madry A, Sanders P, Kistler PM, Lee G. Absence of rotational activity detected using 2-dimensional phase mapping in the corresponding 3-dimensional phase maps in human persistent atrial fibrillation. Heart Rhythm. 2018 Feb; 15(2):182-192. PMID: 28917553.
      View in: PubMed
    8. Pathik B, Kalman JM, Walters T, Kuklik P, Zhao J, Madry A, Prabhu S, Nalliah C, Kistler P, Lee G. Transient Rotor Activity During Prolonged 3-Dimensional Phase Mapping in Human Persistent Atrial Fibrillation. JACC Clin Electrophysiol. 2018 Jan; 4(1):72-83. PMID: 29600788.
      View in: PubMed
    9. Walters TE, Kalman JM, Patel SK, Mearns M, Velkoska E, Burrell LM. Angiotensin converting enzyme 2 activity and human atrial fibrillation: increased plasma angiotensin converting enzyme 2 activity is associated with atrial fibrillation and more advanced left atrial structural remodelling. Europace. 2017 Aug 01; 19(8):1280-1287. PMID: 27738071.
      View in: PubMed
    10. Szilágyi J, Marcus GM, Badhwar N, Lee BK, Lee RJ, Vedantham V, Tseng ZH, Walters T, Scheinman M, Olgin J, Gerstenfeld EP. Atrial fibrillation patients with isolated pulmonary veins: Is sinus rhythm achievable? J Cardiovasc Electrophysiol. 2017 Jul; 28(7):754-761. PMID: 28429499.
      View in: PubMed
    11. Nazer B, Walters TE, Duggirala S, Gerstenfeld EP. Feasibility of Rapid Linear-Endocardial and Epicardial Ventricular Ablation Using an Irrigated Multipolar Radiofrequency Ablation Catheter. Circ Arrhythm Electrophysiol. 2017 Mar; 10(3). PMID: 28288961.
      View in: PubMed
    12. Gerstenfeld EP, Walters T. Amiodarone for Suppression of Ventricular Tachycardia: When Less Is More. JACC Clin Electrophysiol. 2017 May; 3(5):512-513. PMID: 29759608.
      View in: PubMed
    13. Janaswamy P, Walters TE, Nazer B, Lee RJ. Current Treatment Strategies for Heart Failure: Role of Device Therapy and LV Reconstruction. Curr Treat Options Cardiovasc Med. 2016 Sep; 18(9):57. PMID: 27488313.
      View in: PubMed
    14. Walters TE, Lee G, Spence S, Kalman JM. The effect of electrode density on the interpretation of atrial activation patterns in epicardial mapping of human persistent atrial fibrillation. Heart Rhythm. 2016 06; 13(6):1215-20. PMID: 26829116.
      View in: PubMed
    15. Walters TE, Nisbet A, Morris GM, Tan G, Mearns M, Teo E, Lewis N, Ng A, Gould P, Lee G, Joseph S, Morton JB, Zentner D, Sanders P, Kistler PM, Kalman JM. Progression of atrial remodeling in patients with high-burden atrial fibrillation: Implications for early ablative intervention. Heart Rhythm. 2016 Feb; 13(2):331-9. PMID: 26484789.
      View in: PubMed
    16. Prabhu S, McLellan AJ, Walters TE, Sharma M, Voskoboinik A, Kistler PM. Atrial structure and function and its implications for current and emerging treatments for atrial fibrillation. Prog Cardiovasc Dis. 2015 Sep-Oct; 58(2):152-67. PMID: 26247494.
      View in: PubMed
    17. Walters TE, Ellims AH, Kalman JM. The role of left atrial imaging in the management of atrial fibrillation. Prog Cardiovasc Dis. 2015 Sep-Oct; 58(2):136-51. PMID: 26241303.
      View in: PubMed
    18. Walters TE, Kalman JM. Human persistent atrial fibrillation is maintained by rotors: the jury is still out. Circ Arrhythm Electrophysiol. 2015 Jun; 8(3):517-9. PMID: 26082522.
      View in: PubMed
    19. McLellan AJ, Ling LH, Azzopardi S, Lee GA, Lee G, Kumar S, Wong MC, Walters TE, Lee JM, Looi KL, Halloran K, Stiles MK, Lever NA, Fynn SP, Heck PM, Sanders P, Morton JB, Kalman JM, Kistler PM. A minimal or maximal ablation strategy to achieve pulmonary vein isolation for paroxysmal atrial fibrillation: a prospective multi-centre randomized controlled trial (the Minimax study). Eur Heart J. 2015 Jul 21; 36(28):1812-21. PMID: 25920401.
      View in: PubMed
    20. Walters TE, Lee G, Morris G, Spence S, Larobina M, Atkinson V, Antippa P, Goldblatt J, Royse A, O'Keefe M, Sanders P, Morton JB, Kistler PM, Kalman JM. Temporal Stability of Rotors and Atrial Activation Patterns in Persistent Human Atrial Fibrillation: A High-Density Epicardial Mapping Study of Prolonged Recordings. JACC Clin Electrophysiol. 2015 Mar - Apr; 1(1-2):14-24. PMID: 29759334.
      View in: PubMed
    21. Walters TE, Lee G, Spence S, Larobina M, Atkinson V, Antippa P, Goldblatt J, O'Keefe M, Sanders P, Kistler PM, Kalman JM. Acute atrial stretch results in conduction slowing and complex signals at the pulmonary vein to left atrial junction: insights into the mechanism of pulmonary vein arrhythmogenesis. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1189-97. PMID: 25516579.
      View in: PubMed
    22. Walters TE, Teh AW, Spence S, Morton JB, Kistler PM, Kalman JM. Absence of gender-based differences in the atrial and pulmonary vein substrate: a detailed electroanatomic mapping study. J Cardiovasc Electrophysiol. 2014 Oct; 25(10):1065-70. PMID: 24902862.
      View in: PubMed
    23. Walters TE, Kalman JM. Development of atrial fibrillation after atrial flutter ablation: more a question of when than whether. J Cardiovasc Electrophysiol. 2014 Aug; 25(8):821-823. PMID: 24762080.
      View in: PubMed
    24. Walters TE, Teh AW, Spence S, Kistler PM, Morton JB, Kalman JM. Relationship between the electrocardiographic atrial fibrillation cycle length and left atrial remodeling: a detailed electroanatomic mapping study. Heart Rhythm. 2014 Apr; 11(4):670-6. PMID: 24378770.
      View in: PubMed
    25. McLellan AJ, Ling LH, Ruggiero D, Wong MC, Walters TE, Nisbet A, Shetty AK, Azzopardi S, Taylor AJ, Morton JB, Kalman JM, Kistler PM. Pulmonary vein isolation: the impact of pulmonary venous anatomy on long-term outcome of catheter ablation for paroxysmal atrial fibrillation. Heart Rhythm. 2014 Apr; 11(4):549-56. PMID: 24342795.
      View in: PubMed
    26. Amerena JV, Walters TE, Mirzaee S, Kalman JM. Update on the management of atrial fibrillation. Med J Aust. 2013 Nov 04; 199(9):592-7. PMID: 24182224.
      View in: PubMed
    27. Kumar S, Walters TE, Halloran K, Morton JB, Hepworth G, Wong CX, Kistler PM, Sanders P, Kalman JM. Ten-year trends in the use of catheter ablation for treatment of atrial fibrillation vs. the use of coronary intervention for the treatment of ischaemic heart disease in Australia. Europace. 2013 Dec; 15(12):1702-9. PMID: 23796617.
      View in: PubMed
    28. Walters TE, Kistler PM, Morton JB, Sparks PB, Halloran K, Kalman JM. Impact of collimation on radiation exposure during interventional electrophysiology. Europace. 2012 Nov; 14(11):1670-3. PMID: 22516059.
      View in: PubMed
    29. Walters TE, Kistler PM, Kalman JM. Radiofrequency ablation for atrial tachycardia and atrial flutter. Heart Lung Circ. 2012 Jun; 21(6-7):386-94. PMID: 22464595.
      View in: PubMed
    30. Pattison DA, Walters TE, Seal E. Exercise-associated hyponatraemia on the Kokoda Track. Med J Aust. 2011 Mar 07; 194(5):247-8. PMID: 21381998.
      View in: PubMed
    31. Wightman F, Walters T, Ayres A, Bowden S, Bartholomeusz A, Lau D, Locarnini S, Lewin SR. Comparison of sequence analysis and a novel discriminatory real-time PCR assay for detection and quantification of Lamivudine-resistant hepatitis B virus strains. J Clin Microbiol. 2004 Aug; 42(8):3809-12. PMID: 15297535; PMCID: PMC497642.
    32. Lewin S, Walters T, Locarnini S. Hepatitis B treatment: rational combination chemotherapy based on viral kinetic and animal model studies. Antiviral Res. 2002 Sep; 55(3):381-96. PMID: 12206877.
      View in: PubMed
    33. Torresi J, Earnest-Silveira L, Civitico G, Walters TE, Lewin SR, Fyfe J, Locarnini SA, Manns M, Trautwein C, Bock TC. Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the "fingers" subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene. Virology. 2002 Jul 20; 299(1):88-99. PMID: 12167344.
      View in: PubMed