Umamaheswaran Gurusamy, PhD

Title(s)Postdoctoral Scholar, Cardiovascular Research Inst
SchoolSchool of Medicine
Address555 Mission Bay Blvd South
San Francisco CA 94158
ORCID ORCID Icon0000-0002-8709-9159 Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    Jawaharlal Institute of Postgraduate Medical Education and Research2017Best PhD Thesis Award
    European Molecular Biology Laboratory2015PhD Symposium Travel Grant
    Indian Journal of Endocrinology and Metabolism2014Best Original Article
    Indian Pharmacological Society2014Best Paper Award
    Department of Science and Technology, India2014Young Scientist Travel Award
    European Molecular Biology Laboratory2014EMBL-CPP Travel Fellowship
    International Surgical Society2013Breast Surgery Best Poster Award
    Indian Science Congress2013Best Poster Award
    Indian Council of Medical Research2013Young Scientist Travel Award
    European Molecular Biology Laboratory2013EMBL-CPP Travel Fellowship
    Indian Atherosclerosis Society2011Best Paper Award

    Collapse Overview 

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. iScience. 2022 Feb 18; 25(2):103760. Sahajpal NS, Jill Lai CY, Hastie A, Mondal AK, Dehkordi SR, van der Made CI, Fedrigo O, Al-Ajli F, Jalnapurkar S, Byrska-Bishop M, Kanagal-Shamanna R, Levy B, Schieck M, Illig T, Bacanu SA, Chou JS, Randolph AG, Rojiani AM, Zody MC, Brownstein CA, Beggs AH, Bafna V, Jarvis ED, Hoischen A, Chaubey A, Kolhe R, COVID19hostgenomesv Consortium. PMID: 35036860; PMCID: PMC8744399.
      View in: PubMed   Mentions: 1  
    2. Polymorphisms of T- cell leukemia 1A gene loci are not related to the development of adjuvant letrozole-induced adverse events in breast cancer . PLOS ONE. 2021; 3(16):e0247989. Gurusamy Umamaheswaran, Dharanipragada Kadambari, Suresh Kumar Muthuvel, Naveena A. N. Kumar, Biswajit Dubashi, Steven Aibor Dkhar, Chandrasekaran Adithan.
    3. Association of CYP19A1 gene variations with adjuvant letrozole-induced adverse events in South Indian postmenopausal breast cancer cohort expressing hormone-receptor positivity. Breast Cancer Res Treat. 2020 Jul; 182(1):147-158. Umamaheswaran G, Kadambari D, Muthuvel SK, Kalaivani S, Devi J, Damodaran SE, Pradhan SC, Dubashi B, Dkhar SA, Adithan C. PMID: 32385792.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Frequency of single nucleotide platelet receptor gene polymorphism (P2Y12-i744T>C) in coronary artery disease patients among Tamilian population. J Community Genet. 2017 Apr; 8(2):127-132. Priyadharsini R, Umamaheswaran G, Raja TA, Arun Kumar AS, Subraja K, Dkhar SA, Satheesh S, Adithan C, Shewade DG. PMID: 28255814; PMCID: PMC5386915.
      View in: PubMed   Mentions:
    5. Endothelial nitric oxide synthase gene polymorphisms are associated with cardiovascular risks in prehypertensives. J Am Soc Hypertens. 2016 11; 10(11):865-872. Pal GK, Adithan C, Umamaheswaran G, Pal P, Nanda N, Indumathy J, Syamsunder AN. PMID: 27697448.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Effect of ADRB2 (adrenergic receptor β2) gene polymorphisms on the occurrence of asthma and on the response to nebulized salbutamol in South Indian patients with bronchial asthma. J Asthma. 2015 Oct; 52(8):755-62. Shah NJ, Vinod Kumar S, Gurusamy U, Annan Sudarsan AK, Shewade DG. PMID: 25985706.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    7. ABCB1 C3435T genetic Polymorphism and response to Glibenclamide therapy in patients with type 2 diabetes mellitus. Int J Pharmacol Clin Sci. 2015; 2(4):12-15. Surendiran A, Pradhan SC, Subrahmanyam DKS, Aparna Agrawal, Umamaheswaran G, Rajan, Adithan C.
    8. Influence of SLC22A1 rs622342 genetic polymorphism on metformin response in South Indian type 2 diabetes mellitus patients. Clin Exp Med. 2015 Nov; 15(4):511-7. Umamaheswaran G, Praveen RG, Damodaran SE, Das AK, Adithan C. PMID: 25492374.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    9. Allele and genotype distributions of DNA repair gene polymorphisms in South Indian healthy population. Biomark Cancer. 2014; 6:29-35. Rao KS, Paul A, Kumar AS, Umamaheswaran G, Dubashi B, Gunaseelan K, Dkhar SA. PMID: 25520562; PMCID: PMC4259864.
      View in: PubMed   Mentions: 2  
    10. Polymorphic genetic variations of cytochrome P450 19A1 and T-cell leukemia 1A genes in the Tamil population. Environ Toxicol Pharmacol. 2015 Jan; 39(1):102-13. Umamaheswaran G, Kadambari D, Kumar AS, Revathy M, Anjana R, Adithan C, Dkhar SA. PMID: 25481307.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Allele and genotype frequency of a genetic variant in ataxia telangiectasia mutated gene affecting glycemic response to metformin in South Indian population. Indian J Endocrinol Metab. 2014 Nov; 18(6):850-4. Vilvanathan S, Gurusamy U, Mukta V, Das AK, Chandrasekaran A. PMID: 25364682; PMCID: PMC4192993.
      View in: PubMed   Mentions: 7  
    12. Association of CYP2C8, CYP2C9 and CYP2J2 gene polymorphisms with myocardial infarction in South Indian population. Pharmacol Rep. 2015 Feb; 67(1):97-101. Arun Kumar AS, Kumar SS, Umamaheswaran G, Kesavan R, Balachandar J, Adithan C. PMID: 25560582.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    13. Single nucleotide polymorphism of CYP3A5*3 contributes to clopidogrel resistance in coronary artery disease patients among Tamilian population. Mol Biol Rep. 2014 Nov; 41(11):7265-71. Priyadharsini R, Shewade DG, Subraja K, Ravindra BK, Umamaheswaran G, Dkhar SA, Satheesh S, Sridhar MG, Narayan SK, Adithan C. PMID: 25112801.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Frequency distribution of DNA repair genes ERCC1 and ERCC2 polymorphisms in South Indian healthy population. Environ Toxicol Pharmacol. 2014 Sep; 38(2):480-8. Rao KS, SureshKumar S, Umamaheswaran G, Paul A, Dubashi B, Gunaseelan K, Dkhar SA. PMID: 25155628.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    15. Genotype, allele and haplotype frequencies of four TCL1A gene polymorphisms associated with musculoskeletal toxicity in the South Indian descent. Bioimpacts. 2014; 4(2):95-100. Umamaheswaran G, Dkhar SA, Kumar AS, Srinivasa RK, Kadambari D, Adithan C. PMID: 25035853; PMCID: PMC4097978.
      View in: PubMed   Mentions: 1  
    16. Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective. Indian J Med Res. 2014 Jan; 139(1):27-65. Umamaheswaran G, Kumar DK, Adithan C. PMID: 24604039; PMCID: PMC3994740.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    17. Cytochrome P450 genetic variants and hypertension risk in South Indian population. Journal of Young Pharmacists. 2014; 6(1):22-26. Arun Kumar AS, Suresh Kumar S, Umamaheswaran G, Balachandar J, Adithan C.
    18. Handbooks of Pharmacogenomics and Stratified Medicine - Sandosh Padmanabhan. Pharmacogenomics in Indian Population. 2014; 1037-1059. Umamaheswaran G, Shewade DG.
    19. Haplotype structures and functional polymorphic variants of the drug target enzyme aromatase (CYP19A1) in South Indian population. Med Oncol. 2013; 30(3):665. Umamaheswaran G, Dkhar SA, Kalaivani S, Anjana R, Revathy M, Jaharamma M, Shree KM, Kadambari D, Adithan C. PMID: 23893151.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. P-glycoprotein expression as a predictor of response to neoadjuvant chemotherapy in breast cancer. Indian J Cancer. 2013 Jul-Sep; 50(3):195-9. Vishnukumar S, Umamaheswaran G, Anichavezhi D, Indumathy S, Adithan C, Srinivasan K, Kadambari D. PMID: 24061458.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Endothelial nitric oxide synthase gene polymorphisms and the risk of acute myocardial infarction in a South Indian population. Mol Biol Rep. 2013 Feb; 40(2):1275-81. Arun Kumar AS, Umamaheswaran G, Padmapriya R, Balachandar J, Adithan C. PMID: 23108994.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. Genetic polymorphisms of CYP2D6 increase the risk for recurrence of breast cancer in patients receiving tamoxifen as an adjuvant therapy. Cancer Chemother Pharmacol. 2012 Jul; 70(1):75-81. Damodaran SE, Pradhan SC, Umamaheswaran G, Kadambari D, Reddy KS, Adithan C. PMID: 22623212.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    23. Inter and intra-ethnic differences in the distribution of the molecular variants of TPMT, UGT1A1 and MDR1 genes in the South Indian population. Mol Biol Rep. 2012 May; 39(5):6343-51. Umamaheswaran G, Krishna Kumar D, Kayathiri D, Rajan S, Shewade DG, Dkhar SA, Manjunath S, Ushakiran P, Reneega G, Ritushree K, Adithan C. PMID: 22318545.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. Genetic analysis of OCT1 gene polymorphisms in an Indian population. Indian J Hum Genet. 2011 Sep; 17(3):164-8. Umamaheswaran G, Praveen RG, Arunkumar AS, Das AK, Shewade DG, Adithan C. PMID: 22345987; PMCID: PMC3276984.
      View in: PubMed   Mentions: 11  
    25. Haplotype structures of common variants of CYP2C8, CYP2C9, and ADRB1 genes in a South Indian population. Genet Test Mol Biomarkers. 2011 Jun; 15(6):407-13. Arun Kumar AS, Chakradhara Rao US, Umamaheswaran G, Ramu P, Kesavan R, Shewade DG, Balachandar J, Adithan C. PMID: 21375401.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. Genetic polymorphisms of drug-metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population. Fundam Clin Pharmacol. 2012 Apr; 26(2):295-306. Krishnakumar D, Gurusamy U, Dhandapani K, Surendiran A, Baghel R, Kukreti R, Gangadhar R, Prayaga U, Manjunath S, Adithan C. PMID: 21265876.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    27. Candidate Gene Polymorphisms of Renin Angiotensin System and Essential Hypertension in a South Indian Tamilian Population. Int J Hum Genet. 2011; 11(1). Ramu P, Umamaheswaran G, Shewade DG, Swaminathan RP, Dutta TK, Balachander J, Adithan C.
    28. Association of aldosterone synthase (CYP11B2 C-344T) gene polymorphism & susceptibility to essential hypertension in a south Indian Tamil population. Indian J Med Res. 2010 Oct; 132:379-85. Rajan S, Ramu P, Umamaheswaran G, Adithan C. PMID: 20966514.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. Gly460Trp polymorphism of the ADD1 gene and essential hypertension in an Indian population: A meta-analysis on hypertension risk. Indian J Hum Genet. 2010 Jan; 16(1):8-15. Ramu P, Umamaheswaran G, Shewade DG, Swaminathan RP, Balachander J, Adithan C. PMID: 20838486; PMCID: PMC2927797.
      View in: PubMed   Mentions: 14  
    30. Gender specific association of endothelial nitric oxide synthase gene (Glu298Asp) polymorphism with essential hypertension in a south Indian population. Clin Chim Acta. 2008 Sep; 395(1-2):134-6. Periaswamy R, Gurusamy U, Shewade DG, Cherian A, Swaminathan RP, Dutta TK, Jayaraman B, Chandrasekaran A. PMID: 18582449.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
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