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Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. iScience. 2022 Feb 18; 25(2):103760.
Sahajpal NS, Jill Lai CY, Hastie A, Mondal AK, Dehkordi SR, van der Made CI, Fedrigo O, Al-Ajli F, Jalnapurkar S, Byrska-Bishop M, Kanagal-Shamanna R, Levy B, Schieck M, Illig T, Bacanu SA, Chou JS, Randolph AG, Rojiani AM, Zody MC, Brownstein CA, Beggs AH, Bafna V, Jarvis ED, Hoischen A, Chaubey A, Kolhe R, COVID19hostgenomesv Consortium. PMID: 35036860; PMCID: PMC8744399.
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Polymorphisms of T- cell leukemia 1A gene loci are not related to the development of
adjuvant letrozole-induced adverse events in breast cancer
. PLOS ONE. 2021; 3(16):e0247989.
Gurusamy Umamaheswaran, Dharanipragada Kadambari, Suresh Kumar Muthuvel,
Naveena A. N. Kumar, Biswajit Dubashi, Steven Aibor Dkhar, Chandrasekaran Adithan.
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Association of CYP19A1 gene variations with adjuvant letrozole-induced adverse events in South Indian postmenopausal breast cancer cohort expressing hormone-receptor positivity. Breast Cancer Res Treat. 2020 Jul; 182(1):147-158.
Umamaheswaran G, Kadambari D, Muthuvel SK, Kalaivani S, Devi J, Damodaran SE, Pradhan SC, Dubashi B, Dkhar SA, Adithan C. PMID: 32385792.
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1 Fields:
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Humans
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Frequency of single nucleotide platelet receptor gene polymorphism (P2Y12-i744T>C) in coronary artery disease patients among Tamilian population. J Community Genet. 2017 Apr; 8(2):127-132.
Priyadharsini R, Umamaheswaran G, Raja TA, Arun Kumar AS, Subraja K, Dkhar SA, Satheesh S, Adithan C, Shewade DG. PMID: 28255814; PMCID: PMC5386915.
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Endothelial nitric oxide synthase gene polymorphisms are associated with cardiovascular risks in prehypertensives. J Am Soc Hypertens. 2016 11; 10(11):865-872.
Pal GK, Adithan C, Umamaheswaran G, Pal P, Nanda N, Indumathy J, Syamsunder AN. PMID: 27697448.
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3 Fields:
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Humans
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Effect of ADRB2 (adrenergic receptor β2) gene polymorphisms on the occurrence of asthma and on the response to nebulized salbutamol in South Indian patients with bronchial asthma. J Asthma. 2015 Oct; 52(8):755-62.
Shah NJ, Vinod Kumar S, Gurusamy U, Annan Sudarsan AK, Shewade DG. PMID: 25985706.
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5 Fields:
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HumansCTClinical Trials
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ABCB1 C3435T genetic Polymorphism and response to Glibenclamide therapy in patients with type 2 diabetes mellitus. Int J Pharmacol Clin Sci. 2015; 2(4):12-15.
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Influence of SLC22A1 rs622342 genetic polymorphism on metformin response in South Indian type 2 diabetes mellitus patients. Clin Exp Med. 2015 Nov; 15(4):511-7.
Umamaheswaran G, Praveen RG, Damodaran SE, Das AK, Adithan C. PMID: 25492374.
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11 Fields:
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Humans
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Allele and genotype distributions of DNA repair gene polymorphisms in South Indian healthy population. Biomark Cancer. 2014; 6:29-35.
Rao KS, Paul A, Kumar AS, Umamaheswaran G, Dubashi B, Gunaseelan K, Dkhar SA. PMID: 25520562; PMCID: PMC4259864.
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2
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Polymorphic genetic variations of cytochrome P450 19A1 and T-cell leukemia 1A genes in the Tamil population. Environ Toxicol Pharmacol. 2015 Jan; 39(1):102-13.
Umamaheswaran G, Kadambari D, Kumar AS, Revathy M, Anjana R, Adithan C, Dkhar SA. PMID: 25481307.
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Humans
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Allele and genotype frequency of a genetic variant in ataxia telangiectasia mutated gene affecting glycemic response to metformin in South Indian population. Indian J Endocrinol Metab. 2014 Nov; 18(6):850-4.
Vilvanathan S, Gurusamy U, Mukta V, Das AK, Chandrasekaran A. PMID: 25364682; PMCID: PMC4192993.
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5
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Association of CYP2C8, CYP2C9 and CYP2J2 gene polymorphisms with myocardial infarction in South Indian population. Pharmacol Rep. 2015 Feb; 67(1):97-101.
Arun Kumar AS, Kumar SS, Umamaheswaran G, Kesavan R, Balachandar J, Adithan C. PMID: 25560582.
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5 Fields:
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Humans
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Single nucleotide polymorphism of CYP3A5*3 contributes to clopidogrel resistance in coronary artery disease patients among Tamilian population. Mol Biol Rep. 2014 Nov; 41(11):7265-71.
Priyadharsini R, Shewade DG, Subraja K, Ravindra BK, Umamaheswaran G, Dkhar SA, Satheesh S, Sridhar MG, Narayan SK, Adithan C. PMID: 25112801.
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4 Fields:
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Humans
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Frequency distribution of DNA repair genes ERCC1 and ERCC2 polymorphisms in South Indian healthy population. Environ Toxicol Pharmacol. 2014 Sep; 38(2):480-8.
Rao KS, SureshKumar S, Umamaheswaran G, Paul A, Dubashi B, Gunaseelan K, Dkhar SA. PMID: 25155628.
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3 Fields:
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HumansCells
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Genotype, allele and haplotype frequencies of four TCL1A gene polymorphisms associated with musculoskeletal toxicity in the South Indian descent. Bioimpacts. 2014; 4(2):95-100.
Umamaheswaran G, Dkhar SA, Kumar AS, Srinivasa RK, Kadambari D, Adithan C. PMID: 25035853; PMCID: PMC4097978.
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1
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Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective. Indian J Med Res. 2014 Jan; 139(1):27-65.
Umamaheswaran G, Kumar DK, Adithan C. PMID: 24604039; PMCID: PMC3994740.
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Humans
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Cytochrome P450 genetic variants and hypertension risk in South Indian population. Journal of Young Pharmacists. 2014; 6(1):22-26.
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Handbooks of Pharmacogenomics and Stratified Medicine - Sandosh Padmanabhan. Pharmacogenomics in Indian Population. 2014; 1037-1059.
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Haplotype structures and functional polymorphic variants of the drug target enzyme aromatase (CYP19A1) in South Indian population. Med Oncol. 2013; 30(3):665.
Umamaheswaran G, Dkhar SA, Kalaivani S, Anjana R, Revathy M, Jaharamma M, Shree KM, Kadambari D, Adithan C. PMID: 23893151.
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3 Fields:
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Humans
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P-glycoprotein expression as a predictor of response to neoadjuvant chemotherapy in breast cancer. Indian J Cancer. 2013 Jul-Sep; 50(3):195-9.
Vishnukumar S, Umamaheswaran G, Anichavezhi D, Indumathy S, Adithan C, Srinivasan K, Kadambari D. PMID: 24061458.
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Humans
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Endothelial nitric oxide synthase gene polymorphisms and the risk of acute myocardial infarction in a South Indian population. Mol Biol Rep. 2013 Feb; 40(2):1275-81.
Arun Kumar AS, Umamaheswaran G, Padmapriya R, Balachandar J, Adithan C. PMID: 23108994.
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5 Fields:
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Humans
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Genetic polymorphisms of CYP2D6 increase the risk for recurrence of breast cancer in patients receiving tamoxifen as an adjuvant therapy. Cancer Chemother Pharmacol. 2012 Jul; 70(1):75-81.
Damodaran SE, Pradhan SC, Umamaheswaran G, Kadambari D, Reddy KS, Adithan C. PMID: 22623212.
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9 Fields:
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Humans
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Inter and intra-ethnic differences in the distribution of the molecular variants of TPMT, UGT1A1 and MDR1 genes in the South Indian population. Mol Biol Rep. 2012 May; 39(5):6343-51.
Umamaheswaran G, Krishna Kumar D, Kayathiri D, Rajan S, Shewade DG, Dkhar SA, Manjunath S, Ushakiran P, Reneega G, Ritushree K, Adithan C. PMID: 22318545.
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8 Fields:
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Humans
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Genetic analysis of OCT1 gene polymorphisms in an Indian population. Indian J Hum Genet. 2011 Sep; 17(3):164-8.
Umamaheswaran G, Praveen RG, Arunkumar AS, Das AK, Shewade DG, Adithan C. PMID: 22345987; PMCID: PMC3276984.
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10
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Haplotype structures of common variants of CYP2C8, CYP2C9, and ADRB1 genes in a South Indian population. Genet Test Mol Biomarkers. 2011 Jun; 15(6):407-13.
Arun Kumar AS, Chakradhara Rao US, Umamaheswaran G, Ramu P, Kesavan R, Shewade DG, Balachandar J, Adithan C. PMID: 21375401.
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6 Fields:
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Humans
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Genetic polymorphisms of drug-metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population. Fundam Clin Pharmacol. 2012 Apr; 26(2):295-306.
Krishnakumar D, Gurusamy U, Dhandapani K, Surendiran A, Baghel R, Kukreti R, Gangadhar R, Prayaga U, Manjunath S, Adithan C. PMID: 21265876.
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Humans
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Candidate Gene Polymorphisms of Renin Angiotensin System and Essential Hypertension in a South Indian Tamilian Population. Int J Hum Genet. 2011; 11(1).
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Association of aldosterone synthase (CYP11B2 C-344T) gene polymorphism & susceptibility to essential hypertension in a south Indian Tamil population. Indian J Med Res. 2010 Oct; 132:379-85.
Rajan S, Ramu P, Umamaheswaran G, Adithan C. PMID: 20966514.
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7 Fields:
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Humans
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Gly460Trp polymorphism of the ADD1 gene and essential hypertension in an Indian population: A meta-analysis on hypertension risk. Indian J Hum Genet. 2010 Jan; 16(1):8-15.
Ramu P, Umamaheswaran G, Shewade DG, Swaminathan RP, Balachander J, Adithan C. PMID: 20838486; PMCID: PMC2927797.
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12
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Gender specific association of endothelial nitric oxide synthase gene (Glu298Asp) polymorphism with essential hypertension in a south Indian population. Clin Chim Acta. 2008 Sep; 395(1-2):134-6.
Periaswamy R, Gurusamy U, Shewade DG, Cherian A, Swaminathan RP, Dutta TK, Jayaraman B, Chandrasekaran A. PMID: 18582449.
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PubMed Mentions:
9 Fields:
Translation:
Humans