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Valerie Weaver, PhD

Title(s)Professor, Surgery
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE
San Francisco CA 94143
Phone415-476-3826
ORCID ORCID Icon0000-0003-4786-6752 Additional info
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    Collapse Research 
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    Targeting the Cancer Glycocalyx
    NIH/NCI R01CA227942Mar 1, 2019 - Feb 29, 2024
    Role: Co-Principal Investigator
    Reorienting the Glioblastoma Microenvironment to Respond to Immunotherapy
    NIH/NINDS R01NS109911Feb 1, 2019 - Jan 31, 2024
    Role: Co-Principal Investigator
    Tissue Tension, RANK and Breast Cancer Risk
    NIH/NCI R01CA222508Feb 9, 2018 - Jan 31, 2023
    Role: Principal Investigator
    Inside-Out Approaches to Improve Wound Repair by HoxB3
    NIH/NIAMS R21AR069495Jul 15, 2016 - Apr 30, 2018
    Role: Principal Investigator
    ECM geometrical and mechanical properties modulate RTK signaling
    NIH/NCI U01CA202241Sep 22, 2015 - Aug 31, 2020
    Role: Co-Principal Investigator
    2015 Fibronectin, Integrins &Related Molecules Gordon Research Conference &Gordon Research Seminar
    NIH/NIAMS R13AR068188May 1, 2015 - Apr 30, 2016
    Role: Principal Investigator
    Tension-Stat3-miR-mediated metastasis
    NIH/NCI R01CA192914Apr 1, 2015 - Mar 31, 2020
    Role: Principal Investigator
    A biophysical stromal basis for radiation sensitivity in ductal carcinoma in situ
    NIH/NCI R01CA174929May 5, 2014 - Feb 28, 2019
    Role: Co-Principal Investigator
    Advanced Methods to Evaluate Extracellular Matrix and Crosslinking in the Tumor M
    NIH/NCI R33CA183685May 2, 2014 - Apr 30, 2017
    Role: Co-Principal Investigator
    2013 Fibronectin, Integrins &Related Molecules GRC/GRS
    NIH/NCI R13CA174204Feb 6, 2013 - Jan 31, 2014
    Role: Principal Investigator
    Biophysical and molecular dialogue of glioma cells and the brain microenvironment
    NIH/NCI U54CA163155Sep 26, 2011 - Jul 31, 2016
    Role: Co-Principal Investigator
    Role of Fibroblasts, Myeloid Cells and Matrix in PDAC
    NIH/NCI U01CA151925Sep 30, 2010 - Aug 31, 2015
    Role: Co-Principal Investigator
    Collagen remodeling and tumor progression
    NIH/NCI R01CA138818May 7, 2010 - Feb 28, 2015
    Role: Principal Investigator
    Fundamental Mechanobiology of Tumor Progression
    NIH U54CA143836Sep 29, 2009 - Jul 31, 2015
    Role: Co-Investigator
    NFkB, tissue polarity and apoptosis resistance
    NIH/NCI R01CA078731Jul 1, 2000 - Nov 30, 2006
    Role: Principal Investigator
    TGF-beta Suppression and Promotion of Mammary Carcinomas
    NIH/NCI R01CA085492May 20, 2000 - Nov 30, 2010
    Role: Co-Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice. Sci Transl Med. 2020 Aug 19; 12(557). Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. PMID: 32817366.
      View in: PubMed   Mentions:    Fields:    
    2. Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix. J Clin Invest. 2020 Aug 04. Jiang H, Torphy RJ, Steiger K, Hongo H, Ritchie AJ, Kriegsmann M, Horst D, Umetsu SE, Joseph NM, McGregor K, Pishvaian MJ, Blais EM, Lu B, Li M, Hollingsworth M, Stashko C, Volmar K, Yeh JJ, Weaver VM, Wang ZJ, Tempero MA, Weichert W, Collisson EA. PMID: 32749238.
      View in: PubMed   Mentions:    Fields:    
    3. Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. J Clin Invest. 2020 Jul 28. Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. PMID: 32721948.
      View in: PubMed   Mentions:    Fields:    
    4. Fibrosis and cancer: A strained relationship. Biochim Biophys Acta Rev Cancer. 2020 04; 1873(2):188356. Piersma B, Hayward MK, Weaver VM. PMID: 32147542.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    5. Tension in tumour cells keeps metabolism high. Nature. 2020 02; 578(7796):517-518. Ayad NME, Weaver VM. PMID: 32094916.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. A framework for advancing our understanding of cancer-associated fibroblasts. Nat Rev Cancer. 2020 03; 20(3):174-186. Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. PMID: 31980749.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    7. Don't sugarcoat it: How glycocalyx composition influences cancer progression. J Cell Biol. 2020 01 06; 219(1). Buffone A, Weaver VM. PMID: 31874115.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics. J Vis Exp. 2019 09 28; (151). Muncie JM, Falcón-Banchs R, Lakins JN, Sohn LL, Weaver VM. PMID: 31609314.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Controlled modelling of human epiblast and amnion development using stem cells. Nature. 2019 09; 573(7774):421-425. Zheng Y, Xue X, Shao Y, Wang S, Esfahani SN, Li Z, Muncie JM, Lakins JN, Weaver VM, Gumucio DL, Fu J. PMID: 31511693.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    10. Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells. Cell Stem Cell. 2019 11 07; 25(5):654-665.e4. Eliazer S, Muncie JM, Christensen J, Sun X, D'Urso RS, Weaver VM, Brack AS. PMID: 31495781.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. Tissue mechanics, an important regulator of development and disease. Philos Trans R Soc Lond B Biol Sci. 2019 08 19; 374(1779):20180215. Ayad NME, Kaushik S, Weaver VM. PMID: 31431174.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    12. The Extracellular Matrix Modulates the Metastatic Journey. Dev Cell. 2019 05 06; 49(3):332-346. Kai F, Drain AP, Weaver VM. PMID: 31063753.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    13. Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. Elife. 2018 10 09; 7. Libby AR, Joy DA, So PL, Mandegar MA, Muncie JM, Mendoza-Camacho FN, Weaver VM, Conklin BR, McDevitt TC. PMID: 30298816.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma. Nat Cell Biol. 2018 10; 20(10):1203-1214. Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. PMID: 30202050.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    15. Modeling Tissue Polarity in Context. J Mol Biol. 2018 09 28; 430(19):3613-3628. Tharp KM, Weaver VM. PMID: 30055167.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    16. Fibronectin rescues estrogen receptor a from lysosomal degradation in breast cancer cells. J Cell Biol. 2018 08 06; 217(8):2777-2798. Sampayo RG, Toscani AM, Rubashkin MG, Thi K, Masullo LA, Violi IL, Lakins JN, Cáceres A, Hines WC, Coluccio Leskow F, Stefani FD, Chialvo DR, Bissell MJ, Weaver VM, Simian M. PMID: 29980625.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    17. The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate. Curr Top Dev Biol. 2018; 130:1-37. Muncie JM, Weaver VM. PMID: 29853174.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    18. New Horizons in Advocacy Engaged Physical Sciences and Oncology Research. Trends Cancer. 2018 04; 4(4):260-264. Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM. PMID: 29606307.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Feeling Stress: The Mechanics of Cancer Progression and Aggression. Front Cell Dev Biol. 2018; 6:17. Northcott JM, Dean IS, Mouw JK, Weaver VM. PMID: 29541636.
      View in: PubMed   Mentions:
    20. Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma. Mol Cancer Res. 2018 05; 16(5):777-790. Ilkhanizadeh S, Sabelström H, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Lakins JN, Schmidt C, Quigley DA, Fenster T, Yuan E, Trzeciak JR, Saxena S, Lindberg OR, Mouw JK, Burdick JA, Magnitsky S, Berger MS, Phillips JJ, Arosio D, Sun D, Weaver VM, Weiss WA, Persson AI. PMID: 29431617.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    21. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018 02 01; 32(3-4):244-257. Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z. PMID: 29483153.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    22. Excess area dependent scaling behavior of nano-sized membrane tethers. Phys Biol. 2018 01 11; 15(2):026002. Ramakrishnan N, Sreeja KK, Roychoudhury A, Eckmann DM, Ayyaswamy PS, Baumgart T, Pucadyil T, Patil S, Weaver VM, Radhakrishnan R. PMID: 29116056.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    23. A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression. Elife. 2017 12 21; 6. Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR. PMID: 29266001.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    24. Tissue Force Programs Cell Fate and Tumor Aggression. Cancer Discov. 2017 11; 7(11):1224-1237. Northey JJ, Przybyla L, Weaver VM. PMID: 29038232.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    25. a5ß1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. Mol Biol Cell. 2017 Nov 01; 28(22):2958-2977. Miroshnikova YA, Rozenberg GI, Cassereau L, Pickup M, Mouw JK, Ou G, Templeman KL, Hannachi EI, Gooch KJ, Sarang-Sieminski AL, García AJ, Weaver VM. PMID: 28877984.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    26. Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells. Cancer Immunol Res. 2017 09; 5(9):718-729. Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL, Novitskiy SV. PMID: 28775207.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    27. Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer. Cancer Res. 2017 11 01; 77(21):5846-5859. Salvador F, Martin A, López-Menéndez C, Moreno-Bueno G, Santos V, Vázquez-Naharro A, Santamaria PG, Morales S, Dubus PR, Muinelo-Romay L, López-López R, Tung JC, Weaver VM, Portillo F, Cano A. PMID: 28720577.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    28. Cell and tissue mechanics: the new cell biology frontier. Mol Biol Cell. 2017 07 07; 28(14):1815-1818. Weaver VM. PMID: 28684606.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    29. Visualizing dynamic microvillar search and stabilization during ligand detection by T cells. Science. 2017 05 12; 356(6338). Cai E, Marchuk K, Beemiller P, Beppler C, Rubashkin MG, Weaver VM, Gérard A, Liu TL, Chen BC, Betzig E, Bartumeus F, Krummel MF. PMID: 28495700.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    30. Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis. Cold Spring Harb Symp Quant Biol. 2016; 81:189-205. Oudin MJ, Weaver VM. PMID: 28424337.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    31. Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy. PLoS One. 2017; 12(4):e0175112. Khuc E, Bainer R, Wolf M, Clay SM, Weisenberger DJ, Kemmer J, Weaver VM, Hwang DG, Chan MF. PMID: 28384203.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    32. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017 Jun 01; 28(11):1467-1488. Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM. PMID: 28381423.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    33. Tissue mechanics regulate brain development, homeostasis and disease. J Cell Sci. 2017 01 01; 130(1):71-82. Barnes JM, Przybyla L, Weaver VM. PMID: 28043968.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    34. Force-dependent breaching of the basement membrane. Matrix Biol. 2017 01; 57-58:178-189. Chang TT, Thakar D, Weaver VM. PMID: 28025167.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    35. Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer. Oncotarget. 2016 Dec 13; 7(50):82889-82901. Takai K, Le A, Weaver VM, Werb Z. PMID: 27756881.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    36. From transformation to metastasis: deconstructing the extracellular matrix in breast cancer. Cancer Metastasis Rev. 2016 12; 35(4):655-667. Kaushik S, Pickup MW, Weaver VM. PMID: 27914000.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    37. Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells. J Exp Med. 2016 12 12; 213(13):2967-2988. Chan TS, Hsu CC, Pai VC, Liao WY, Huang SS, Tan KT, Yen CJ, Hsu SC, Chen WY, Shan YS, Li CR, Lee MT, Jiang KY, Chu JM, Lien GS, Weaver VM, Tsai KK. PMID: 27881732.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    38. Tissue mechanics promote IDH1-dependent HIF1a-tenascin C feedback to regulate glioblastoma aggression. Nat Cell Biol. 2016 Dec; 18(12):1336-1345. Miroshnikova YA, Mouw JK, Barnes JM, Pickup MW, Lakins JN, Kim Y, Lobo K, Persson AI, Reis GF, McKnight TR, Holland EC, Phillips JJ, Weaver VM. PMID: 27820599.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    39. Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease. Semin Cell Dev Biol. 2017 07; 67:141-152. Gilbert PM, Weaver VM. PMID: 27641825.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    40. Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation. Cell Stem Cell. 2016 10 06; 19(4):462-475. Przybyla L, Lakins JN, Weaver VM. PMID: 27452175.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    41. Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions. Integr Biol (Camb). 2016 07 11; 8(7):795-804. Ou G, Thakar D, Tung JC, Miroshnikova YA, Dufort CC, Gutierrez E, Groisman A, Weaver VM. PMID: 27334548.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    42. Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer. Annu Rev Cell Dev Biol. 2016 10 06; 32:527-554. Przybyla L, Muncie JM, Weaver VM. PMID: 27298087.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    43. Site-Specific Modulation of Charge Controls the Structure and Stimulus Responsiveness of Intrinsically Disordered Peptide Brushes. Langmuir. 2016 06 14; 32(23):5990-6. Bhagawati M, Rubashkin MG, Lee JP, Ananthanarayanan B, Weaver VM, Kumar S. PMID: 27203736.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    44. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 05; 22(5):497-505. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. PMID: 27089513.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    45. Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease. Trends Cell Biol. 2016 07; 26(7):486-497. Kai F, Laklai H, Weaver VM. PMID: 27056543.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    46. Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. J Cell Biol. 2016 Mar 14; 212(6):707-19. Le LT, Cazares O, Mouw JK, Chatterjee S, Macias H, Moran A, Ramos J, Keely PJ, Weaver VM, Hinck L. PMID: 26975850.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    47. Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha. Hepatology. 2016 07; 64(1):261-75. Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT. PMID: 26755329.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    48. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. PMID: 28843279.
      View in: PubMed   Mentions: 22     Fields:    
    49. Tumor-induced solid stress activates ß-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells. Bioessays. 2015 Dec; 37(12):1293-7. Ou G, Weaver VM. PMID: 26439949.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    50. Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors. Mol Biol Cell. 2015 Nov 05; 26(22):3946-53. Lin CH, Pelissier FA, Zhang H, Lakins J, Weaver VM, Park C, LaBarge MA. PMID: 26337386.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    51. Monitoring developmental force distributions in reconstituted embryonic epithelia. Methods. 2016 Feb 01; 94:101-13. Przybyla L, Lakins JN, Sunyer R, Trepat X, Weaver VM. PMID: 26342256.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    52. STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma. Cancer Res. 2015 Oct 15; 75(20):4302-11. Lau J, Ilkhanizadeh S, Wang S, Miroshnikova YA, Salvatierra NA, Wong RA, Schmidt C, Weaver VM, Weiss WA, Persson AI. PMID: 26282165.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    53. Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration. Integr Biol (Camb). 2015 Oct; 7(10):1120-34. Acerbi I, Cassereau L, Dean I, Shi Q, Au A, Park C, Chen YY, Liphardt J, Hwang ES, Weaver VM. PMID: 25959051.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansCells
    54. Fighting the force: Potential of homeobox genes for tumor microenvironment regulation. Biochim Biophys Acta. 2015 Apr; 1855(2):248-53. Northcott JM, Northey JJ, Barnes JM, Weaver VM. PMID: 25818365.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    55. Tumor mechanics and metabolic dysfunction. Free Radic Biol Med. 2015 Feb; 79:269-80. Tung JC, Barnes JM, Desai SR, Sistrunk C, Conklin MW, Schedin P, Eliceiri KW, Keely PJ, Seewaldt VL, Weaver VM. PMID: 25532934.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    56. A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype. J Biotechnol. 2015 Jan 10; 193:66-9. Cassereau L, Miroshnikova YA, Ou G, Lakins J, Weaver VM. PMID: 25435379.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    57. The extracellular matrix modulates the hallmarks of cancer. EMBO Rep. 2014 Dec; 15(12):1243-53. Pickup MW, Mouw JK, Weaver VM. PMID: 25381661.
      View in: PubMed   Mentions: 255     Fields:    Translation:HumansCells
    58. Extracellular matrix assembly: a multiscale deconstruction. Nat Rev Mol Cell Biol. 2014 Dec; 15(12):771-85. Mouw JK, Ou G, Weaver VM. PMID: 25370693.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansAnimalsCells
    59. The microenvironment matters. Mol Biol Cell. 2014 Nov 01; 25(21):3254-8. Weaver VM. PMID: 25360044.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014 Sep 01; 74(17):4597-611. Rubashkin MG, Cassereau L, Bainer R, DuFort CC, Yui Y, Ou G, Paszek MJ, Davidson MW, Chen YY, Weaver VM. PMID: 25183785.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    61. Multicellular architecture of malignant breast epithelia influences mechanics. PLoS One. 2014; 9(8):e101955. Venugopalan G, Camarillo DB, Webster KD, Reber CD, Sethian JA, Weaver VM, Fletcher DA, El-Samad H, Rycroft CH. PMID: 25111489.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    62. The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 2014 Jul 17; 511(7509):319-25. Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM. PMID: 25030168.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    63. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. PMID: 24856586.
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    64. Understanding tissue context influences on intratumour heterogeneity. Nat Cell Biol. 2014 Apr; 16(4):301-2. Michor F, Weaver VM. PMID: 24691256.
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    65. Deconstructing signaling in three dimensions. Biochemistry. 2014 Apr 08; 53(13):2078-90. Rubashkin MG, Ou G, Weaver VM. PMID: 24649923.
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    66. Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nat Med. 2014 Apr; 20(4):360-7. Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM. PMID: 24633304.
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    67. Rapid disorganization of mechanically interacting systems of mammary acini. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):658-63. Shi Q, Ghosh RP, Engelke H, Rycroft CH, Cassereau L, Sethian JA, Weaver VM, Liphardt JT. PMID: 24379367.
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    68. Cell biology. Strength under tension. Science. 2013 Aug 30; 341(6149):965-6. Bainer R, Weaver V. PMID: 23990548.
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    69. Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-ß-deficient mouse mammary carcinomas. Cancer Res. 2013 Sep 01; 73(17):5336-46. Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL. PMID: 23856251.
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    70. Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci. 2013 Sep 15; 126(Pt 18):4108-10. Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. PMID: 23843613.
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    71. Oncogenic targeting of BRM drives malignancy through C/EBPß-dependent induction of a5 integrin. Oncogene. 2014 May 08; 33(19):2441-53. Damiano L, Stewart KM, Cohet N, Mouw JK, Lakins JN, Debnath J, Reisman D, Nickerson JA, Imbalzano AN, Weaver VM. PMID: 23770848.
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    72. YAP forces fibroblasts to feel the tension. Nat Cell Biol. 2013 Jun; 15(6):570-2. Maller O, DuFort CC, Weaver VM. PMID: 23728464.
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    73. MT1-MMP-dependent control of skeletal stem cell commitment via a ß1-integrin/YAP/TAZ signaling axis. Dev Cell. 2013 May 28; 25(4):402-16. Tang Y, Rowe RG, Botvinick EL, Kurup A, Putnam AJ, Seiki M, Weaver VM, Keller ET, Goldstein S, Dai J, Begun D, Saunders T, Weiss SJ. PMID: 23685250.
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    74. A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep. 2013; 3:1449. Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O'Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH. PMID: 23618955.
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    75. Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer. Am J Pathol. 2013 Feb; 182(2):363-74. Li CR, Su JJ, Wang WY, Lee MT, Wang TY, Jiang KY, Li CF, Hsu JM, Chen CK, Chen M, Jiang SS, Weaver VM, Tsai KK. PMID: 23219426.
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    76. Scanning angle interference microscopy reveals cell dynamics at the nanoscale. Nat Methods. 2012 Jul 01; 9(8):825-7. Paszek MJ, DuFort CC, Rubashkin MG, Davidson MW, Thorn KS, Liphardt JT, Weaver VM. PMID: 22751201.
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    77. Morphogenesis: Laying down the tracks. Nat Mater. 2012 May 22; 11(6):490-2. Cassereau L, DuFort CC, Weaver VM. PMID: 22614514.
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    78. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol. 2012 Feb 20; 196(4):395-406. Lu P, Weaver VM, Werb Z. PMID: 22351925.
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    79. Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels. Methods Mol Biol. 2012; 916:317-50. Lakins JN, Chin AR, Weaver VM. PMID: 22914951.
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    80. Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol. 2011 Dec 01; 3(12). Lu P, Takai K, Weaver VM, Werb Z. PMID: 21917992.
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    81. In situ force mapping of mammary gland transformation. Integr Biol (Camb). 2011 Sep; 3(9):910-21. Lopez JI, Kang I, You WK, McDonald DM, Weaver VM. PMID: 21842067.
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    82. Actomyosin-mediated cellular tension drives increased tissue stiffness and ß-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer Cell. 2011 Jun 14; 19(6):776-91. Samuel MS, Lopez JI, McGhee EJ, Croft DR, Strachan D, Timpson P, Munro J, Schröder E, Zhou J, Brunton VG, Barker N, Clevers H, Sansom OJ, Anderson KI, Weaver VM, Olson MF. PMID: 21665151.
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    83. Valerie Weaver: overcoming cancer's stiff resistance. Interview by Caitlin Sedwick. J Cell Biol. 2011 May 30; 193(5):802-3. Weaver V. PMID: 21624950.
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    84. Tumor microenvironment and progression. J Surg Oncol. 2011 May 01; 103(6):468-74. Dvorak HF, Weaver VM, Tlsty TD, Bergers G. PMID: 21480238.
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    85. Balancing forces: architectural control of mechanotransduction. Nat Rev Mol Cell Biol. 2011 May; 12(5):308-19. DuFort CC, Paszek MJ, Weaver VM. PMID: 21508987.
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    86. Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties. Phys Biol. 2011 Apr; 8(2):026013. Miroshnikova YA, Jorgens DM, Spirio L, Auer M, Sarang-Sieminski AL, Weaver VM. PMID: 21441648.
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    87. The extracellular matrix at a glance. J Cell Sci. 2010 Dec 15; 123(Pt 24):4195-200. Frantz C, Stewart KM, Weaver VM. PMID: 21123617.
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    88. Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: implications for atherosclerosis. J Cell Physiol. 2010 Oct; 225(1):115-22. Brown XQ, Bartolak-Suki E, Williams C, Walker ML, Weaver VM, Wong JY. PMID: 20648629.
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    89. Forcing form and function: biomechanical regulation of tumor evolution. Trends Cell Biol. 2011 Jan; 21(1):47-56. Yu H, Mouw JK, Weaver VM. PMID: 20870407.
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    90. Dynamic interplay between the collagen scaffold and tumor evolution. Curr Opin Cell Biol. 2010 Oct; 22(5):697-706. Egeblad M, Rasch MG, Weaver VM. PMID: 20822891.
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    91. SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells. J Cell Physiol. 2010 Jun; 223(3):667-78. Cohet N, Stewart KM, Mudhasani R, Asirvatham AJ, Mallappa C, Imbalzano KM, Weaver VM, Imbalzano AN, Nickerson JA. PMID: 20333683.
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    92. HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. J Clin Invest. 2010 May; 120(5):1535-50. Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM. PMID: 20389018.
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    93. Biophysics. Enforcing order on signaling. Science. 2010 Mar 12; 327(5971):1335-6. Paszek M, Weaver V. PMID: 20223974.
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    94. Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate. PLoS Comput Biol. 2009 Dec; 5(12):e1000604. Paszek MJ, Boettiger D, Weaver VM, Hammer DA. PMID: 20011123.
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    95. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell. 2009 Nov 25; 139(5):891-906. Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. PMID: 19931152.
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    96. Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Cancer Metastasis Rev. 2009 Jun; 28(1-2):113-27. Kumar S, Weaver VM. PMID: 19153673.
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    97. Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Mol Biol Cell. 2009 Jul; 20(14):3224-38. Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ. PMID: 19458194.
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    98. The tissue diagnostic instrument. Rev Sci Instrum. 2009 May; 80(5):054303. Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, Mellbovsky L, Peña MJ, Diez-Ferrer O, Mathews P, Randall C, Kuo A, Chen C, Peters M, Kohn D, Buckley J, Li X, Pruitt L, Diez-Perez A, Alliston T, Weaver V, Lotz J. PMID: 19485522.
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    99. Multiscale modeling of form and function. Science. 2009 Apr 10; 324(5924):208-12. Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM. PMID: 19359578.
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    100. CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. Cancer Epidemiol Biomarkers Prev. 2009 Mar; 18(3):901-14. Vasilatos SN, Broadwater G, Barry WT, Baker JC, Lem S, Dietze EC, Bean GR, Bryson AD, Pilie PG, Goldenberg V, Skaar D, Paisie C, Torres-Hernandez A, Grant TL, Wilke LG, Ibarra-Drendall C, Ostrander JH, D'Amato NC, Zalles C, Jirtle R, Weaver VM, Seewaldt VL. PMID: 19258476.
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    101. A tense situation: forcing tumour progression. Nat Rev Cancer. 2009 Feb; 9(2):108-22. Butcher DT, Alliston T, Weaver VM. PMID: 19165226.
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    102. Biomechanical regulation of cell orientation and fate. Oncogene. 2008 Nov 24; 27(55):6981-93. Lopez JI, Mouw JK, Weaver VM. PMID: 19029939.
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    103. Three-dimensional context regulation of metastasis. Clin Exp Metastasis. 2009; 26(1):35-49. Erler JT, Weaver VM. PMID: 18814043.
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    104. A human breast cell model of preinvasive to invasive transition. Cancer Res. 2008 Mar 01; 68(5):1378-87. Rizki A, Weaver VM, Lee SY, Rozenberg GI, Chin K, Myers CA, Bascom JL, Mott JD, Semeiks JR, Grate LR, Mian IS, Borowsky AD, Jensen RA, Idowu MO, Chen F, Chen DJ, Petersen OW, Gray JW, Bissell MJ. PMID: 18316601.
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    105. Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion. J Cell Sci. 2008 Jan 15; 121(Pt 2):226-33. Fournier AK, Campbell LE, Castagnino P, Liu WF, Chung BM, Weaver VM, Chen CS, Assoian RK. PMID: 18187454.
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    106. Integrin-mediated signalling through the MAP-kinase pathway. IET Syst Biol. 2008 Jan; 2(1):8-15. Yee KL, Weaver VM, Hammer DA. PMID: 18248081.
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    107. Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures. Annu Rev Pathol. 2008; 3:313-39. Hebner C, Weaver VM, Debnath J. PMID: 18039125.
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    108. alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini. J Cell Sci. 2007 Oct 15; 120(Pt 20):3700-12. Friedland JC, Lakins JN, Kazanietz MG, Chernoff J, Boettiger D, Weaver VM. PMID: 17911169.
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    109. G'rab'bing the microenvironment for invasion. Dev Cell. 2007 Oct; 13(4):462-3. Weaver V, Werb Z. PMID: 17925222.
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    110. Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. Int J Biochem Cell Biol. 2007; 39(11):1987-94. Kass L, Erler JT, Dembo M, Weaver VM. PMID: 17719831.
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    111. Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis. Methods Cell Biol. 2007; 83:547-83. Johnson KR, Leight JL, Weaver VM. PMID: 17613324.
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    112. The ultrastructure of MCF-10A acini. J Cell Physiol. 2006 Jul; 208(1):141-8. Underwood JM, Imbalzano KM, Weaver VM, Fischer AH, Imbalzano AN, Nickerson JA. PMID: 16607610.
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    113. Forcing the third dimension. Cell. 2006 May 05; 125(3):429-31. Boudreau N, Weaver V. PMID: 16678088.
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    114. Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard. J Proteome Res. 2005 Nov-Dec; 4(6):2007-14. Yan Y, Weaver VM, Blair IA. PMID: 16335945.
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    115. Tensional homeostasis and the malignant phenotype. Cancer Cell. 2005 Sep; 8(3):241-54. Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM. PMID: 16169468.
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    116. Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin. J Biol Chem. 2005 Jul 01; 280(26):24363-70. Yang C, Liu Y, Leskow FC, Weaver VM, Kazanietz MG. PMID: 15863513.
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    117. Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression. Mol Biol Cell. 2005 Apr; 16(4):1901-12. Cowden Dahl KD, Robertson SE, Weaver VM, Simon MC. PMID: 15689487.
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    118. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil Cytoskeleton. 2005 Jan; 60(1):24-34. Yeung T, Georges PC, Flanagan LA, Marg B, Ortiz M, Funaki M, Zahir N, Ming W, Weaver V, Janmey PA. PMID: 15573414.
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    119. The tension mounts: mechanics meets morphogenesis and malignancy. J Mammary Gland Biol Neoplasia. 2004 Oct; 9(4):325-42. Paszek MJ, Weaver VM. PMID: 15838603.
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    120. Watch thy neighbor: cancer is a communal affair. J Cell Sci. 2004 Mar 15; 117(Pt 8):1287-90. Weaver VM, Gilbert P. PMID: 15020668.
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    121. Death in the third dimension: apoptosis regulation and tissue architecture. Curr Opin Genet Dev. 2004 Feb; 14(1):71-80. Zahir N, Weaver VM. PMID: 15108808.
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    122. Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors. J Cell Biol. 2003 Dec 22; 163(6):1397-407. Zahir N, Lakins JN, Russell A, Ming W, Chatterjee C, Rozenberg GI, Marinkovich MP, Weaver VM. PMID: 14691145.
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    123. Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin. J Cell Sci. 2003 Sep 01; 116(Pt 17):3543-56. Russell AJ, Fincher EF, Millman L, Smith R, Vela V, Waterman EA, Dey CN, Guide S, Weaver VM, Marinkovich MP. PMID: 12865436.
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    124. The tissue microenvironment as an epigenetic tumor modifier. Methods Mol Biol. 2003; 223:315-47. Unger M, Weaver VM. PMID: 12777739.
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    125. The organizing principle: microenvironmental influences in the normal and malignant breast. Differentiation. 2002 Dec; 70(9-10):537-46. Bissell MJ, Radisky DC, Rizki A, Weaver VM, Petersen OW. PMID: 12492495.
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    126. beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002 Sep; 2(3):205-16. Weaver VM, Lelièvre S, Lakins JN, Chrenek MA, Jones JC, Giancotti F, Werb Z, Bissell MJ. PMID: 12242153.
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    127. Membrane-associated MMP regulators: novel cell adhesion tumor suppressor proteins? Dev Cell. 2002 Jan; 2(1):6-7. Weaver VM. PMID: 11782309.
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    128. Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation. Breast Cancer Res. 2001; 3(4):224-9. Chrenek MA, Wong P, Weaver VM. PMID: 11434873.
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    129. Lack of specificity of trans,trans-muconic acid as a benzene biomarker after ingestion of sorbic acid-preserved foods. Cancer Epidemiol Biomarkers Prev. 2000 Jul; 9(7):749-55. Weaver VM, Buckley T, Groopman JD. PMID: 10919747.
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    130. E7-transduced human breast epithelial cells show partial differentiation in three-dimensional culture. Cancer Res. 1999 Dec 15; 59(24):6042-5. Spancake KM, Anderson CB, Weaver VM, Matsunami N, Bissell MJ, White RL. PMID: 10626787.
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    131. Constitutive expression of Heregulin induces apoptosis in an erbB-2 overexpressing breast cancer cell line SKBr-3. Int J Oncol. 1999 Nov; 15(5):883-92. Guerra-Vladusic FK, Scott G, Weaver V, Vladusic EA, Tsai MS, Benz CC, Lupu R. PMID: 10536169.
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    132. Functional culture models to study mechanisms governing apoptosis in normal and malignant mammary epithelial cells. J Mammary Gland Biol Neoplasia. 1999 Apr; 4(2):193-201. Weaver VM, Bissell MJ. PMID: 10426398.
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    133. Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res. 1999 Apr 01; 59(7 Suppl):1757-1763s; discussion 1763s-1764s. Bissell MJ, Weaver VM, Lelièvre SA, Wang F, Petersen OW, Schmeichel KL. PMID: 10197593.
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    134. Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14711-6. Lelièvre SA, Weaver VM, Nickerson JA, Larabell CA, Bhaumik A, Petersen OW, Bissell MJ. PMID: 9843954.
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    135. Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14821-6. Wang F, Weaver VM, Petersen OW, Larabell CA, Dedhar S, Briand P, Lupu R, Bissell MJ. PMID: 9843973.
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    136. Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype. J Mammary Gland Biol Neoplasia. 1998 Apr; 3(2):201-13. Schmeichel KL, Weaver VM, Bissell MJ. PMID: 10819528.
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    137. Differentiation and cancer in the mammary gland: shedding light on an old dichotomy. Adv Cancer Res. 1998; 75:135-61. Petersen OW, Rønnov-Jessen L, Weaver VM, Bissell MJ. PMID: 9709809.
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    138. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol. 1997 Apr 07; 137(1):231-45. Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ. PMID: 9105051.
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    139. Extracellular matrix: the central regulator of cell and tissue homeostasis. Trends Cell Biol. 1997 Jan; 7(1):40-2. Weaver VM, Roskelley CD. PMID: 17708898.
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    140. Extracellular matrix signaling from the cellular membrane skeleton to the nuclear skeleton: a model of gene regulation. Recent Prog Horm Res. 1996; 51:417-32. Lelièvre S, Weaver VM, Bissell MJ. PMID: 8701089.
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