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Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option. Nat Cell Biol. 2024 Oct 24.
Uroz M, Stoddard AE, Sutherland BP, Courbot O, Oria R, Li L, Ravasio CR, Ngo MT, Yang J, Tefft JB, Eyckmans J, Han X, Elosegui-Artola A, Weaver VM, Chen CS. PMID: 39448802.
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PubMed Mentions: Fields:
-
Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling. bioRxiv. 2024 Sep 28.
Nakagawa R, Beardsley A, Durney S, Hayward MK, Subramanyam V, Meyer NP, Wismer H, Goodarzi H, Weaver VM, Van de Mark D, Goga A. PMID: 39386679; PMCID: PMC11463411.
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PubMed Mentions:
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nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer. bioRxiv. 2024 Sep 25.
Hendley AM, Ashe S, Urano A, Ng M, Phu TA, Peng XL, Luan C, Finger AM, Jang GH, Kerper NR, Berrios DI, Jin D, Lee J, Riahi IR, Gbenedio OM, Chung C, Roose JP, Yeh JJ, Gallinger S, Biankin AV, O'Kane GM, Ntranos V, Chang DK, Dawson DW, Kim GE, Weaver VM, Raffai RL, Hebrok M. PMID: 39399775; PMCID: PMC11468832.
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PubMed Mentions:
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Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment. Nat Cancer. 2024 Jul; 5(7):1045-1062.
Tharp KM, Kersten K, Maller O, Timblin GA, Stashko C, Canale FP, Menjivar RE, Hayward MK, Berestjuk I, Ten Hoeve J, Samad B, Ironside AJ, di Magliano MP, Muir A, Geiger R, Combes AJ, Weaver VM. PMID: 38831058.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Patterning and folding of intestinal villi by active mesenchymal dewetting. Cell. 2024 Jun 06; 187(12):3072-3089.e20.
Huycke TR, Häkkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, Oria R, Weaver VM, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ. PMID: 38781967; PMCID: PMC11166531.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Imaging the extracellular matrix in live tissues and organisms with a glycan-binding fluorophore. bioRxiv. 2024 May 10.
Fiore A, Yu G, Northey JJ, Patel R, Ravenscroft TA, Ikegami R, Kolkman W, Kumar P, Grimm JB, Dilan TL, Ruetten VMS, Ahrens MB, Shroff H, Lavis LD, Wang S, Weaver VM, Pedram K. PMID: 38766047; PMCID: PMC11100790.
View in:
PubMed Mentions:
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Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies. Proc Natl Acad Sci U S A. 2024 May 14; 121(20):e2322688121.
Goyette MA, Stevens LE, DePinho CR, Seehawer M, Nishida J, Li Z, Wilde CM, Li R, Qiu X, Pyke AL, Zhao S, Lim K, Tender GS, Northey JJ, Riley NM, Long HW, Bertozzi CR, Weaver VM, Polyak K. PMID: 38709925; PMCID: PMC11098130.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Asymmetric crowders and membrane morphology at the nexus of intracellular trafficking and oncology. Mechanobiol Med. 2024 Sep; 2(3).
Parihar K, Ko SB, Bradley RP, Taylor P, Ramakrishnan N, Baumgart T, Guo W, Weaver VM, Janmey PA, Radhakrishnan R. PMID: 38899029; PMCID: PMC11185830.
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PubMed Mentions:
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Free energy calculations for membrane morphological transformations and insights to physical biology and oncology. Methods Enzymol. 2024; 701:359-386.
Parihar K, Ko SH, Bradley R, Taylor P, Ramakrishnan N, Baumgart T, Guo W, Weaver VM, Janmey PA, Radhakrishnan R. PMID: 39025576; PMCID: PMC11258396.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry. bioRxiv. 2024 Mar 31.
Darula Z, McCabe MC, Barrett A, Schmitt LR, Maslanka MD, Saviola AJ, Orgel J, Burlingame A, Staab-Weijnitz CA, Stenmark K, Weaver V, Chalkley RJ, Hansen KC. PMID: 38585857; PMCID: PMC10996605.
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PubMed Mentions:
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Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth. Cancer Cell. 2024 Feb 12; 42(2):317.
Samuel MS, Lopez JI, McGhee EJ, Croft DR, Strachan D, Timpson P, Munro J, Schröder E, Zhou J, Brunton VG, Barker N, Clevers H, Sansom OJ, Anderson KI, Weaver VM, Olson MF. PMID: 38350422; PMCID: PMC10871601.
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PubMed Mentions:
1 Fields:
-
Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk. Cell Stem Cell. 2024 01 04; 31(1):106-126.e13.
Northey JJ, Hayward MK, Yui Y, Stashko C, Kai F, Mouw JK, Thakar D, Lakins JN, Ironside AJ, Samson S, Mukhtar RA, Hwang ES, Weaver VM. PMID: 38181747; PMCID: PMC11050720.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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The microenvironment dictates glycocalyx construction and immune surveillance. Res Sq. 2023 Aug 16.
Tharp KM, Park S, Timblin GA, Richards AL, Berg JA, Twells NM, Riley NM, Peltan EL, Shon DJ, Stevenson E, Tsui K, Palomba F, Lefebvre AEYT, Soens RW, Ayad NME, Hoeve-Scott JT, Healy K, Digman M, Dillin A, Bertozzi CR, Swaney DL, Mahal LK, Cantor JR, Paszek MJ, Weaver VM. PMID: 37645943; PMCID: PMC10462183.
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PubMed Mentions:
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Design of a mucin-selective protease for targeted degradation of cancer-associated mucins. Nat Biotechnol. 2024 Apr; 42(4):597-607.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. PMID: 37537499; PMCID: PMC11018308.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells. bioRxiv. 2023 Jul 15.
Ayad NME, Lakins JN, Ghagre A, Ehrlicher AJ, Weaver VM. PMID: 37503095; PMCID: PMC10370032.
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PubMed Mentions:
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A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer. Nat Commun. 2023 06 15; 14(1):3561.
Stashko C, Hayward MK, Northey JJ, Pearson N, Ironside AJ, Lakins JN, Oria R, Goyette MA, Mayo L, Russnes HG, Hwang ES, Kutys ML, Polyak K, Weaver VM. PMID: 37322009; PMCID: PMC10272194.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung. Cell Rep. 2023 06 27; 42(6):112582.
Kersten K, You R, Liang S, Tharp KM, Pollack J, Weaver VM, Krummel MF, Headley MB. PMID: 37261951; PMCID: PMC10592447.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Stiff matrix induces exosome secretion to promote tumour growth. Nat Cell Biol. 2023 03; 25(3):415-424.
Wu B, Liu DA, Guan L, Myint PK, Chin L, Dang H, Xu Y, Ren J, Li T, Yu Z, Jabban S, Mills GB, Nukpezah J, Chen YH, Furth EE, Gimotty PA, Wells RG, Weaver VM, Radhakrishnan R, Wang XW, Guo W. PMID: 36797475; PMCID: PMC10351222.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Programming the Self-Organization of Endothelial Cells into Perfusable Microvasculature. Tissue Eng Part A. 2023 02; 29(3-4):80-92.
Cabral KA, Srivastava V, Graham AJ, Coyle MC, Stashko C, Weaver V, Gartner ZJ. PMID: 36181350; PMCID: PMC10266707.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Extracellular Matrix Glycation and Crosslinking in Mammary Tumor Progression. Methods Mol Biol. 2023; 2614:247-260.
Northey JJ, Weaver VM. PMID: 36587129; PMCID: PMC10977607.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality. Mol Biol Cell. 2022 12 01; 33(14):br28.
Gaietta G, Kai F, Swift MF, Weaver VM, Volkmann N, Hanein D. PMID: 36287913; PMCID: PMC9727794.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Mechanosensitive Steroid Hormone Signaling and Cell Fate. Endocrinology. 2022 08 01; 163(8).
Northey JJ, Weaver VM. PMID: 35678467; PMCID: PMC9237634.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer. Oncogene. 2022 09; 41(36):4211-4230.
Bell ES, Shah P, Zuela-Sopilniak N, Kim D, Varlet AA, Morival JLP, McGregor AL, Isermann P, Davidson PM, Elacqua JJ, Lakins JN, Vahdat L, Weaver VM, Smolka MB, Span PN, Lammerding J. PMID: 35896617; PMCID: PMC9925375.
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PubMed Mentions:
31 Fields:
Translation:
Humans
-
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells. EMBO J. 2022 09 01; 41(17):e109205.
Kai F, Ou G, Tourdot RW, Stashko C, Gaietta G, Swift MF, Volkmann N, Long AF, Han Y, Huang HH, Northey JJ, Leidal AM, Viasnoff V, Bryant DM, Guo W, Wiita AP, Guo M, Dumont S, Hanein D, Radhakrishnan R, Weaver VM. PMID: 35880301; PMCID: PMC9434103.
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PubMed Mentions:
8 Fields:
Translation:
Cells
-
Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity. Nat Cancer. 2022 06; 3(6):734-752.
Tsai KK, Huang SS, Northey JJ, Liao WY, Hsu CC, Cheng LH, Werner ME, Chuu CP, Chatterjee C, Lakins JN, Weaver VM. PMID: 35618935; PMCID: PMC9246917.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression. Matrix Biol Plus. 2022 Jun; 14:100105.
Metcalf KJ, Hayward MK, Berens E, Ironside AJ, Stashko C, Hwang ES, Weaver VM. PMID: 35392183; PMCID: PMC8981759.
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PubMed Mentions:
7
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NCI's publication affiliation conundrum: Reframing innovation to incentivize an equitable path for advocate representation. Transl Oncol. 2022 Feb; 16:101325.
Samson S, Northey JJ, Acerbi I, Goga A, Flink CL, Weaver VM, LaBarge MA. PMID: 34974281; PMCID: PMC8728534.
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PubMed Mentions:
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Mechanobiology: forcing the second act. Mol Biol Cell. 2021 08 19; 32(18):1611-1613.
Weaver VM. PMID: 34410838; PMCID: PMC8684731.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev. 2021 07 01; 35(13-14):963-975.
Rudnick JA, Monkkonen T, Mar FA, Barnes JM, Starobinets H, Goldsmith J, Roy S, Bustamante Eguiguren S, Weaver VM, Debnath J. PMID: 34168038; PMCID: PMC8247603.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Tissue mechanics in stem cell fate, development, and cancer. Dev Cell. 2021 07 12; 56(13):1833-1847.
Hayward MK, Muncie JM, Weaver VM. PMID: 34107299; PMCID: PMC9056158.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts. J Cell Biol. 2021 06 07; 220(6).
Kindberg AA, Srivastava V, Muncie JM, Weaver VM, Gartner ZJ, Bush JO. PMID: 33798261; PMCID: PMC8025214.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Adhesion-mediated mechanosignaling forces mitohormesis. Cell Metab. 2021 07 06; 33(7):1322-1341.e13.
Tharp KM, Higuchi-Sanabria R, Timblin GA, Ford B, Garzon-Coral C, Schneider C, Muncie JM, Stashko C, Daniele JR, Moore AS, Frankino PA, Homentcovschi S, Manoli SS, Shao H, Richards AL, Chen KH, Hoeve JT, Ku GM, Hellerstein M, Nomura DK, Saijo K, Gestwicki J, Dunn AR, Krogan NJ, Swaney DL, Dillin A, Weaver VM. PMID: 34019840; PMCID: PMC8266765.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. Elife. 2021 05 19; 10.
Hendley AM, Rao AA, Leonhardt L, Ashe S, Smith JA, Giacometti S, Peng XL, Jiang H, Berrios DI, Pawlak M, Li LY, Lee J, Collisson EA, Anderson MS, Fragiadakis GK, Yeh JJ, Ye CJ, Kim GE, Weaver VM, Hebrok M. PMID: 34009124; PMCID: PMC8184217.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer. J Exp Med. 2021 05 03; 218(5).
Drain AP, Zahir N, Northey JJ, Zhang H, Huang PJ, Maller O, Lakins JN, Yu X, Leight JL, Alston-Mills BP, Hwang ES, Chen YY, Park CC, Weaver VM. PMID: 33822843; PMCID: PMC8025243.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Improving DCIS diagnosis and predictive outcome by applying artificial intelligence. Biochim Biophys Acta Rev Cancer. 2021 08; 1876(1):188555.
Hayward MK, Weaver VM. PMID: 33933557; PMCID: PMC10217774.
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PubMed Mentions: Fields:
Translation:
Humans
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Leveraging microenvironmental synthetic lethalities to treat cancer. J Clin Invest. 2021 03 15; 131(6).
Metcalf KJ, Alazzeh A, Werb Z, Weaver VM. PMID: 33720045; PMCID: PMC7954586.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Membrane Tension Locks In Pluripotency. Cell Stem Cell. 2021 02 04; 28(2):175-176.
Muncie JM, Weaver VM. PMID: 33545073.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Derivation of a nuclear heterogeneity image index to grade DCIS. Comput Struct Biotechnol J. 2020; 18:4063-4070.
Hayward MK, Louise Jones J, Hall A, King L, Ironside AJ, Nelson AC, Shelley Hwang E, Weaver VM. PMID: 33363702; PMCID: PMC7744935.
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PubMed Mentions:
4
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Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nat Mater. 2021 04; 20(4):548-559.
Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM. PMID: 33257795; PMCID: PMC8005404.
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PubMed Mentions:
97 Fields:
Translation:
HumansCells
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Proteoglycans as Mediators of Cancer Tissue Mechanics. Front Cell Dev Biol. 2020; 8:569377.
Barkovskaya A, Buffone A, Žídek M, Weaver VM. PMID: 33330449; PMCID: PMC7734320.
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PubMed Mentions:
21
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Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells. Dev Cell. 2020 12 21; 55(6):679-694.e11.
Muncie JM, Ayad NME, Lakins JN, Xue X, Fu J, Weaver VM. PMID: 33207224; PMCID: PMC7755684.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. J Clin Invest. 2020 11 02; 130(11):5721-5737.
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. PMID: 32721948; PMCID: PMC7598051.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimals
-
Zena Werb (1945-2020): Mourning the loss of a tissue microenvironment icon. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):27759-27760.
Weaver VM, Bissell MJ. PMID: 33122428; PMCID: PMC7668183.
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Translation:
HumansCells
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In Memoriam - Zena Werb 1945-2020. J Mammary Gland Biol Neoplasia. 2020 09; 25(3):179-180.
Barcellos-Hoff MH, Weaver VM. PMID: 32997280.
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PubMed Mentions: Fields:
-
Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix. J Clin Invest. 2020 09 01; 130(9):4704-4709.
Jiang H, Torphy RJ, Steiger K, Hongo H, Ritchie AJ, Kriegsmann M, Horst D, Umetsu SE, Joseph NM, McGregor K, Pishvaian MJ, Blais EM, Lu B, Li M, Hollingsworth M, Stashko C, Volmar K, Yeh JJ, Weaver VM, Wang ZJ, Tempero MA, Weichert W, Collisson EA. PMID: 32749238; PMCID: PMC7456216.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice. Sci Transl Med. 2020 08 19; 12(557).
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. PMID: 32817366; PMCID: PMC7976849.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Zena Werb 1945-2020. Nat Cancer. 2020 08; 1(8):753-754.
Egeblad M, Coussens LM, Weaver VM. PMID: 35122050.
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PubMed Mentions:
1 Fields:
-
Fibrosis and cancer: A strained relationship. Biochim Biophys Acta Rev Cancer. 2020 04; 1873(2):188356.
Piersma B, Hayward MK, Weaver VM. PMID: 32147542; PMCID: PMC7733542.
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PubMed Mentions:
227 Fields:
Translation:
HumansCells
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Tension in tumour cells keeps metabolism high. Nature. 2020 02; 578(7796):517-518.
Ayad NME, Weaver VM. PMID: 32094916.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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A framework for advancing our understanding of cancer-associated fibroblasts. Nat Rev Cancer. 2020 03; 20(3):174-186.
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. PMID: 31980749; PMCID: PMC7046529.
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PubMed Mentions:
1415 Fields:
Translation:
HumansAnimalsCells
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Don't sugarcoat it: How glycocalyx composition influences cancer progression. J Cell Biol. 2020 01 06; 219(1).
Buffone A, Weaver VM. PMID: 31874115; PMCID: PMC7039198.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics. J Vis Exp. 2019 09 28; (151).
Muncie JM, Falcón-Banchs R, Lakins JN, Sohn LL, Weaver VM. PMID: 31609314; PMCID: PMC9359695.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Controlled modelling of human epiblast and amnion development using stem cells. Nature. 2019 09; 573(7774):421-425.
Zheng Y, Xue X, Shao Y, Wang S, Esfahani SN, Li Z, Muncie JM, Lakins JN, Weaver VM, Gumucio DL, Fu J. PMID: 31511693; PMCID: PMC8106232.
View in:
PubMed Mentions:
200 Fields:
Translation:
HumansCells
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Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells. Cell Stem Cell. 2019 11 07; 25(5):654-665.e4.
Eliazer S, Muncie JM, Christensen J, Sun X, D'Urso RS, Weaver VM, Brack AS. PMID: 31495781; PMCID: PMC6842437.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Tissue mechanics, an important regulator of development and disease. Philos Trans R Soc Lond B Biol Sci. 2019 08 19; 374(1779):20180215.
Ayad NME, Kaushik S, Weaver VM. PMID: 31431174; PMCID: PMC6627022.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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The Extracellular Matrix Modulates the Metastatic Journey. Dev Cell. 2019 05 06; 49(3):332-346.
Kai F, Drain AP, Weaver VM. PMID: 31063753; PMCID: PMC6527347.
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PubMed Mentions:
236 Fields:
Translation:
HumansAnimalsCells
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Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. Elife. 2018 10 09; 7.
Libby AR, Joy DA, So PL, Mandegar MA, Muncie JM, Mendoza-Camacho FN, Weaver VM, Conklin BR, McDevitt TC. PMID: 30298816; PMCID: PMC6177255.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma. Nat Cell Biol. 2018 10; 20(10):1203-1214.
Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. PMID: 30202050; PMCID: PMC6932748.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Modeling Tissue Polarity in Context. J Mol Biol. 2018 09 28; 430(19):3613-3628.
Tharp KM, Weaver VM. PMID: 30055167; PMCID: PMC6150793.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells. J Cell Biol. 2018 08 06; 217(8):2777-2798.
Sampayo RG, Toscani AM, Rubashkin MG, Thi K, Masullo LA, Violi IL, Lakins JN, Cáceres A, Hines WC, Coluccio Leskow F, Stefani FD, Chialvo DR, Bissell MJ, Weaver VM, Simian M. PMID: 29980625; PMCID: PMC6080927.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Compartment resolved proteomics reveals a dynamic matrisome in a biomechanically driven model of pancreatic ductal adenocarcinoma. J Immunol Regen Med. 2018 Mar; 1:67-75.
Barrett AS, Maller O, Pickup MW, Weaver VM, Hansen KC. PMID: 36908331; PMCID: PMC10003644.
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PubMed Mentions:
7
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The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate. Curr Top Dev Biol. 2018; 130:1-37.
Muncie JM, Weaver VM. PMID: 29853174; PMCID: PMC6586474.
View in:
PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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New Horizons in Advocacy Engaged Physical Sciences and Oncology Research. Trends Cancer. 2018 04; 4(4):260-264.
Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM. PMID: 29606307; PMCID: PMC6932745.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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Feeling Stress: The Mechanics of Cancer Progression and Aggression. Front Cell Dev Biol. 2018; 6:17.
Northcott JM, Dean IS, Mouw JK, Weaver VM. PMID: 29541636; PMCID: PMC5835517.
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PubMed Mentions:
160
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Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma. Mol Cancer Res. 2018 05; 16(5):777-790.
Ilkhanizadeh S, Sabelström H, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Lakins JN, Schmidt C, Quigley DA, Fenster T, Yuan E, Trzeciak JR, Saxena S, Lindberg OR, Mouw JK, Burdick JA, Magnitsky S, Berger MS, Phillips JJ, Arosio D, Sun D, Weaver VM, Weiss WA, Persson AI. PMID: 29431617; PMCID: PMC5932284.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018 02 01; 32(3-4):244-257.
Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z. PMID: 29483153; PMCID: PMC5859966.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Excess area dependent scaling behavior of nano-sized membrane tethers. Phys Biol. 2018 01 11; 15(2):026002.
Ramakrishnan N, Sreeja KK, Roychoudhury A, Eckmann DM, Ayyaswamy PS, Baumgart T, Pucadyil T, Patil S, Weaver VM, Radhakrishnan R. PMID: 29116056; PMCID: PMC5832653.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
-
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression. Elife. 2017 12 21; 6.
Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR. PMID: 29266001; PMCID: PMC5739539.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Tissue Force Programs Cell Fate and Tumor Aggression. Cancer Discov. 2017 11; 7(11):1224-1237.
Northey JJ, Przybyla L, Weaver VM. PMID: 29038232; PMCID: PMC5679454.
View in:
PubMed Mentions:
115 Fields:
Translation:
HumansCells
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α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. Mol Biol Cell. 2017 Nov 01; 28(22):2958-2977.
Miroshnikova YA, Rozenberg GI, Cassereau L, Pickup M, Mouw JK, Ou G, Templeman KL, Hannachi EI, Gooch KJ, Sarang-Sieminski AL, García AJ, Weaver VM. PMID: 28877984; PMCID: PMC5662256.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells. Cancer Immunol Res. 2017 09; 5(9):718-729.
Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL, Novitskiy SV. PMID: 28775207; PMCID: PMC5581681.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer. Cancer Res. 2017 11 01; 77(21):5846-5859.
Salvador F, Martin A, López-Menéndez C, Moreno-Bueno G, Santos V, Vázquez-Naharro A, Santamaria PG, Morales S, Dubus PR, Muinelo-Romay L, López-López R, Tung JC, Weaver VM, Portillo F, Cano A. PMID: 28720577; PMCID: PMC5656180.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansAnimalsCells
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Cell and tissue mechanics: the new cell biology frontier. Mol Biol Cell. 2017 07 07; 28(14):1815-1818.
Weaver VM. PMID: 28684606; PMCID: PMC5541832.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Visualizing dynamic microvillar search and stabilization during ligand detection by T cells. Science. 2017 05 12; 356(6338).
Cai E, Marchuk K, Beemiller P, Beppler C, Rubashkin MG, Weaver VM, Gérard A, Liu TL, Chen BC, Betzig E, Bartumeus F, Krummel MF. PMID: 28495700; PMCID: PMC6364556.
View in:
PubMed Mentions:
135 Fields:
Translation:
AnimalsCells
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Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis. Cold Spring Harb Symp Quant Biol. 2016; 81:189-205.
Oudin MJ, Weaver VM. PMID: 28424337.
View in:
PubMed Mentions:
85 Fields:
Translation:
HumansAnimalsCells
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Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy. PLoS One. 2017; 12(4):e0175112.
Khuc E, Bainer R, Wolf M, Clay SM, Weisenberger DJ, Kemmer J, Weaver VM, Hwang DG, Chan MF. PMID: 28384203; PMCID: PMC5383226.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017 Jun 01; 28(11):1467-1488.
Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM. PMID: 28381423; PMCID: PMC5449147.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansCells
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Tissue mechanics regulate brain development, homeostasis and disease. J Cell Sci. 2017 01 01; 130(1):71-82.
Barnes JM, Przybyla L, Weaver VM. PMID: 28043968; PMCID: PMC5394781.
View in:
PubMed Mentions:
113 Fields:
Translation:
HumansAnimalsCells
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Force-dependent breaching of the basement membrane. Matrix Biol. 2017 01; 57-58:178-189.
Chang TT, Thakar D, Weaver VM. PMID: 28025167; PMCID: PMC5328923.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansCells
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Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer. Oncotarget. 2016 Dec 13; 7(50):82889-82901.
Takai K, Le A, Weaver VM, Werb Z. PMID: 27756881; PMCID: PMC5341254.
View in:
PubMed Mentions:
105 Fields:
Translation:
HumansAnimalsCells
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From transformation to metastasis: deconstructing the extracellular matrix in breast cancer. Cancer Metastasis Rev. 2016 12; 35(4):655-667.
Kaushik S, Pickup MW, Weaver VM. PMID: 27914000; PMCID: PMC5215979.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
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Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells. J Exp Med. 2016 12 12; 213(13):2967-2988.
Chan TS, Hsu CC, Pai VC, Liao WY, Huang SS, Tan KT, Yen CJ, Hsu SC, Chen WY, Shan YS, Li CR, Lee MT, Jiang KY, Chu JM, Lien GS, Weaver VM, Tsai KK. PMID: 27881732; PMCID: PMC5154935.
View in:
PubMed Mentions:
93 Fields:
Translation:
HumansCells
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Tissue mechanics promote IDH1-dependent HIF1α-tenascin C feedback to regulate glioblastoma aggression. Nat Cell Biol. 2016 Dec; 18(12):1336-1345.
Miroshnikova YA, Mouw JK, Barnes JM, Pickup MW, Lakins JN, Kim Y, Lobo K, Persson AI, Reis GF, McKnight TR, Holland EC, Phillips JJ, Weaver VM. PMID: 27820599; PMCID: PMC5361403.
View in:
PubMed Mentions:
156 Fields:
Translation:
HumansCells
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Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease. Semin Cell Dev Biol. 2017 07; 67:141-152.
Gilbert PM, Weaver VM. PMID: 27641825; PMCID: PMC5352546.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation. Cell Stem Cell. 2016 10 06; 19(4):462-475.
Przybyla L, Lakins JN, Weaver VM. PMID: 27452175; PMCID: PMC5336327.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansAnimalsCells
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Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions. Integr Biol (Camb). 2016 07 11; 8(7):795-804.
Ou G, Thakar D, Tung JC, Miroshnikova YA, Dufort CC, Gutierrez E, Groisman A, Weaver VM. PMID: 27334548; PMCID: PMC4980125.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer. Annu Rev Cell Dev Biol. 2016 10 06; 32:527-554.
Przybyla L, Muncie JM, Weaver VM. PMID: 27298087.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Site-Specific Modulation of Charge Controls the Structure and Stimulus Responsiveness of Intrinsically Disordered Peptide Brushes. Langmuir. 2016 06 14; 32(23):5990-6.
Bhagawati M, Rubashkin MG, Lee JP, Ananthanarayanan B, Weaver VM, Kumar S. PMID: 27203736; PMCID: PMC5343758.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 05; 22(5):497-505.
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. PMID: 27089513; PMCID: PMC4860133.
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PubMed Mentions:
304 Fields:
Translation:
HumansAnimalsCells
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Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease. Trends Cell Biol. 2016 07; 26(7):486-497.
Kai F, Laklai H, Weaver VM. PMID: 27056543; PMCID: PMC4970516.
View in:
PubMed Mentions:
114 Fields:
Translation:
HumansAnimalsCells
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Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. J Cell Biol. 2016 Mar 14; 212(6):707-19.
Le LT, Cazares O, Mouw JK, Chatterjee S, Macias H, Moran A, Ramos J, Keely PJ, Weaver VM, Hinck L. PMID: 26975850; PMCID: PMC4792073.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha. Hepatology. 2016 07; 64(1):261-75.
Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT. PMID: 26755329; PMCID: PMC5224931.
View in:
PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833.
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. PMID: 28843279.
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PubMed Mentions:
93 Fields:
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Tumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells. Bioessays. 2015 Dec; 37(12):1293-7.
Ou G, Weaver VM. PMID: 26439949; PMCID: PMC4731088.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors. Mol Biol Cell. 2015 Nov 05; 26(22):3946-53.
Lin CH, Pelissier FA, Zhang H, Lakins J, Weaver VM, Park C, LaBarge MA. PMID: 26337386; PMCID: PMC4710228.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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Monitoring developmental force distributions in reconstituted embryonic epithelia. Methods. 2016 Feb 01; 94:101-13.
Przybyla L, Lakins JN, Sunyer R, Trepat X, Weaver VM. PMID: 26342256; PMCID: PMC4761493.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma. Cancer Res. 2015 Oct 15; 75(20):4302-11.
Lau J, Ilkhanizadeh S, Wang S, Miroshnikova YA, Salvatierra NA, Wong RA, Schmidt C, Weaver VM, Weiss WA, Persson AI. PMID: 26282165; PMCID: PMC4609277.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration. Integr Biol (Camb). 2015 Oct; 7(10):1120-34.
Acerbi I, Cassereau L, Dean I, Shi Q, Au A, Park C, Chen YY, Liphardt J, Hwang ES, Weaver VM. PMID: 25959051; PMCID: PMC4593730.
View in:
PubMed Mentions:
467 Fields:
Translation:
HumansCells
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Fighting the force: Potential of homeobox genes for tumor microenvironment regulation. Biochim Biophys Acta. 2015 Apr; 1855(2):248-53.
Northcott JM, Northey JJ, Barnes JM, Weaver VM. PMID: 25818365; PMCID: PMC4433566.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Tumor mechanics and metabolic dysfunction. Free Radic Biol Med. 2015 Feb; 79:269-80.
Tung JC, Barnes JM, Desai SR, Sistrunk C, Conklin MW, Schedin P, Eliceiri KW, Keely PJ, Seewaldt VL, Weaver VM. PMID: 25532934; PMCID: PMC4339308.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
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A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype. J Biotechnol. 2015 Jan 10; 193:66-9.
Cassereau L, Miroshnikova YA, Ou G, Lakins J, Weaver VM. PMID: 25435379; PMCID: PMC4454500.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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The extracellular matrix modulates the hallmarks of cancer. EMBO Rep. 2014 Dec; 15(12):1243-53.
Pickup MW, Mouw JK, Weaver VM. PMID: 25381661; PMCID: PMC4264927.
View in:
PubMed Mentions:
851 Fields:
Translation:
HumansCells
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Extracellular matrix assembly: a multiscale deconstruction. Nat Rev Mol Cell Biol. 2014 Dec; 15(12):771-85.
Mouw JK, Ou G, Weaver VM. PMID: 25370693; PMCID: PMC4682873.
View in:
PubMed Mentions:
534 Fields:
Translation:
HumansAnimalsCells
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The microenvironment matters. Mol Biol Cell. 2014 Nov 01; 25(21):3254-8.
Weaver VM. PMID: 25360044; PMCID: PMC4214768.
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PubMed Mentions: Fields:
Translation:
Humans
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Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014 Sep 01; 74(17):4597-611.
Rubashkin MG, Cassereau L, Bainer R, DuFort CC, Yui Y, Ou G, Paszek MJ, Davidson MW, Chen YY, Weaver VM. PMID: 25183785; PMCID: PMC4191931.
View in:
PubMed Mentions:
109 Fields:
Translation:
HumansAnimalsCells
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Multicellular architecture of malignant breast epithelia influences mechanics. PLoS One. 2014; 9(8):e101955.
Venugopalan G, Camarillo DB, Webster KD, Reber CD, Sethian JA, Weaver VM, Fletcher DA, El-Samad H, Rycroft CH. PMID: 25111489; PMCID: PMC4128597.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 2014 Jul 17; 511(7509):319-25.
Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM. PMID: 25030168; PMCID: PMC4487551.
View in:
PubMed Mentions:
309 Fields:
Translation:
HumansAnimalsCells
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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34.
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. PMID: 24856586; PMCID: PMC4180632.
View in:
PubMed Mentions:
1189 Fields:
Translation:
HumansAnimalsCells
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Understanding tissue context influences on intratumour heterogeneity. Nat Cell Biol. 2014 Apr; 16(4):301-2.
Michor F, Weaver VM. PMID: 24691256; PMCID: PMC4180082.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Deconstructing signaling in three dimensions. Biochemistry. 2014 Apr 08; 53(13):2078-90.
Rubashkin MG, Ou G, Weaver VM. PMID: 24649923; PMCID: PMC3985742.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nat Med. 2014 Apr; 20(4):360-7.
Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM. PMID: 24633304; PMCID: PMC3981899.
View in:
PubMed Mentions:
204 Fields:
Translation:
HumansAnimalsCells
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Rapid disorganization of mechanically interacting systems of mammary acini. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):658-63.
Shi Q, Ghosh RP, Engelke H, Rycroft CH, Cassereau L, Sethian JA, Weaver VM, Liphardt JT. PMID: 24379367; PMCID: PMC3896145.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansCells
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Cell biology. Strength under tension. Science. 2013 Aug 30; 341(6149):965-6.
Bainer R, Weaver V. PMID: 23990548.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas. Cancer Res. 2013 Sep 01; 73(17):5336-46.
Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL. PMID: 23856251; PMCID: PMC3766496.
View in:
PubMed Mentions:
102 Fields:
Translation:
HumansAnimalsCells
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Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci. 2013 Sep 15; 126(Pt 18):4108-10.
Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. PMID: 23843613; PMCID: PMC3772386.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin. Oncogene. 2014 May 08; 33(19):2441-53.
Damiano L, Stewart KM, Cohet N, Mouw JK, Lakins JN, Debnath J, Reisman D, Nickerson JA, Imbalzano AN, Weaver VM. PMID: 23770848; PMCID: PMC3960370.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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YAP forces fibroblasts to feel the tension. Nat Cell Biol. 2013 Jun; 15(6):570-2.
Maller O, DuFort CC, Weaver VM. PMID: 23728464.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis. Dev Cell. 2013 May 28; 25(4):402-16.
Tang Y, Rowe RG, Botvinick EL, Kurup A, Putnam AJ, Seiki M, Weaver VM, Keller ET, Goldstein S, Dai J, Begun D, Saunders T, Weiss SJ. PMID: 23685250; PMCID: PMC3736823.
View in:
PubMed Mentions:
136 Fields:
Translation:
HumansAnimalsCells
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A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep. 2013; 3:1449.
Physical Sciences - Oncology Centers Network, Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O'Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH. PMID: 23618955; PMCID: PMC3636513.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCells
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Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer. Am J Pathol. 2013 Feb; 182(2):363-74.
Li CR, Su JJ, Wang WY, Lee MT, Wang TY, Jiang KY, Li CF, Hsu JM, Chen CK, Chen M, Jiang SS, Weaver VM, Tsai KK. PMID: 23219426; PMCID: PMC3562735.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Scanning angle interference microscopy reveals cell dynamics at the nanoscale. Nat Methods. 2012 Jul 01; 9(8):825-7.
Paszek MJ, DuFort CC, Rubashkin MG, Davidson MW, Thorn KS, Liphardt JT, Weaver VM. PMID: 22751201; PMCID: PMC3454456.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansCells
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Morphogenesis: Laying down the tracks. Nat Mater. 2012 May 22; 11(6):490-2.
Cassereau L, DuFort CC, Weaver VM. PMID: 22614514.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol. 2012 Feb 20; 196(4):395-406.
Lu P, Weaver VM, Werb Z. PMID: 22351925; PMCID: PMC3283993.
View in:
PubMed Mentions:
1360 Fields:
Translation:
HumansCells
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Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels. Methods Mol Biol. 2012; 916:317-50.
Lakins JN, Chin AR, Weaver VM. PMID: 22914951.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol. 2011 Dec 01; 3(12).
Lu P, Takai K, Weaver VM, Werb Z. PMID: 21917992; PMCID: PMC3225943.
View in:
PubMed Mentions:
949 Fields:
Translation:
AnimalsCells
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In situ force mapping of mammary gland transformation. Integr Biol (Camb). 2011 Sep; 3(9):910-21.
Lopez JI, Kang I, You WK, McDonald DM, Weaver VM. PMID: 21842067; PMCID: PMC3564969.
View in:
PubMed Mentions:
149 Fields:
Translation:
AnimalsCells
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Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer Cell. 2011 Jun 14; 19(6):776-91.
Samuel MS, Lopez JI, McGhee EJ, Croft DR, Strachan D, Timpson P, Munro J, Schröder E, Zhou J, Brunton VG, Barker N, Clevers H, Sansom OJ, Anderson KI, Weaver VM, Olson MF. PMID: 21665151; PMCID: PMC3115541.
View in:
PubMed Mentions:
273 Fields:
Translation:
HumansAnimalsCells
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Valerie Weaver: overcoming cancer's stiff resistance. Interview by Caitlin Sedwick. J Cell Biol. 2011 May 30; 193(5):802-3.
Weaver V. PMID: 21624950; PMCID: PMC3105548.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Tumor microenvironment and progression. J Surg Oncol. 2011 May 01; 103(6):468-74.
Dvorak HF, Weaver VM, Tlsty TD, Bergers G. PMID: 21480238; PMCID: PMC3277953.
View in:
PubMed Mentions:
88 Fields:
Translation:
Humans
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Balancing forces: architectural control of mechanotransduction. Nat Rev Mol Cell Biol. 2011 May; 12(5):308-19.
DuFort CC, Paszek MJ, Weaver VM. PMID: 21508987; PMCID: PMC3564968.
View in:
PubMed Mentions:
407 Fields:
Translation:
HumansAnimalsCells
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Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties. Phys Biol. 2011 Apr; 8(2):026013.
Miroshnikova YA, Jorgens DM, Spirio L, Auer M, Sarang-Sieminski AL, Weaver VM. PMID: 21441648; PMCID: PMC3401181.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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The extracellular matrix at a glance. J Cell Sci. 2010 Dec 15; 123(Pt 24):4195-200.
Frantz C, Stewart KM, Weaver VM. PMID: 21123617; PMCID: PMC2995612.
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PubMed Mentions:
1517 Fields:
Translation:
HumansAnimalsCells
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Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: implications for atherosclerosis. J Cell Physiol. 2010 Oct; 225(1):115-22.
Brown XQ, Bartolak-Suki E, Williams C, Walker ML, Weaver VM, Wong JY. PMID: 20648629; PMCID: PMC2920297.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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Forcing form and function: biomechanical regulation of tumor evolution. Trends Cell Biol. 2011 Jan; 21(1):47-56.
Yu H, Mouw JK, Weaver VM. PMID: 20870407; PMCID: PMC3014395.
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PubMed Mentions:
160 Fields:
Translation:
HumansAnimalsCells
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Dynamic interplay between the collagen scaffold and tumor evolution. Curr Opin Cell Biol. 2010 Oct; 22(5):697-706.
Egeblad M, Rasch MG, Weaver VM. PMID: 20822891; PMCID: PMC2948601.
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PubMed Mentions:
415 Fields:
Translation:
Humans
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SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells. J Cell Physiol. 2010 Jun; 223(3):667-78.
Cohet N, Stewart KM, Mudhasani R, Asirvatham AJ, Mallappa C, Imbalzano KM, Weaver VM, Imbalzano AN, Nickerson JA. PMID: 20333683; PMCID: PMC3320666.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. J Clin Invest. 2010 May; 120(5):1535-50.
Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM. PMID: 20389018; PMCID: PMC2860938.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimals
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Biophysics. Enforcing order on signaling. Science. 2010 Mar 12; 327(5971):1335-6.
Paszek M, Weaver V. PMID: 20223974.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate. PLoS Comput Biol. 2009 Dec; 5(12):e1000604.
Paszek MJ, Boettiger D, Weaver VM, Hammer DA. PMID: 20011123; PMCID: PMC2782178.
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PubMed Mentions:
102 Fields:
Translation:
Cells
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Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell. 2009 Nov 25; 139(5):891-906.
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. PMID: 19931152; PMCID: PMC2788004.
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PubMed Mentions:
1943 Fields:
Translation:
HumansAnimalsCells
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Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Cancer Metastasis Rev. 2009 Jun; 28(1-2):113-27.
Kumar S, Weaver VM. PMID: 19153673; PMCID: PMC2658728.
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PubMed Mentions:
407 Fields:
Translation:
HumansAnimalsCells
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Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Mol Biol Cell. 2009 Jul; 20(14):3224-38.
Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ. PMID: 19458194; PMCID: PMC2710838.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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The tissue diagnostic instrument. Rev Sci Instrum. 2009 May; 80(5):054303.
Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, Mellbovsky L, Peña MJ, Diez-Ferrer O, Mathews P, Randall C, Kuo A, Chen C, Peters M, Kohn D, Buckley J, Li X, Pruitt L, Diez-Perez A, Alliston T, Weaver V, Lotz J. PMID: 19485522; PMCID: PMC2832056.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
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Multiscale modeling of form and function. Science. 2009 Apr 10; 324(5924):208-12.
Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM. PMID: 19359578; PMCID: PMC4527531.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. Cancer Epidemiol Biomarkers Prev. 2009 Mar; 18(3):901-14.
Vasilatos SN, Broadwater G, Barry WT, Baker JC, Lem S, Dietze EC, Bean GR, Bryson AD, Pilie PG, Goldenberg V, Skaar D, Paisie C, Torres-Hernandez A, Grant TL, Wilke LG, Ibarra-Drendall C, Ostrander JH, D'Amato NC, Zalles C, Jirtle R, Weaver VM, Seewaldt VL. PMID: 19258476; PMCID: PMC2667866.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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A tense situation: forcing tumour progression. Nat Rev Cancer. 2009 Feb; 9(2):108-22.
Butcher DT, Alliston T, Weaver VM. PMID: 19165226; PMCID: PMC2649117.
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PubMed Mentions:
878 Fields:
Translation:
HumansAnimalsCells
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Biomechanical regulation of cell orientation and fate. Oncogene. 2008 Nov 24; 27(55):6981-93.
Lopez JI, Mouw JK, Weaver VM. PMID: 19029939; PMCID: PMC2648514.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Three-dimensional context regulation of metastasis. Clin Exp Metastasis. 2009; 26(1):35-49.
Erler JT, Weaver VM. PMID: 18814043; PMCID: PMC2648515.
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PubMed Mentions:
148 Fields:
Translation:
Humans
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A human breast cell model of preinvasive to invasive transition. Cancer Res. 2008 Mar 01; 68(5):1378-87.
Rizki A, Weaver VM, Lee SY, Rozenberg GI, Chin K, Myers CA, Bascom JL, Mott JD, Semeiks JR, Grate LR, Mian IS, Borowsky AD, Jensen RA, Idowu MO, Chen F, Chen DJ, Petersen OW, Gray JW, Bissell MJ. PMID: 18316601; PMCID: PMC2662716.
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PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion. J Cell Sci. 2008 Jan 15; 121(Pt 2):226-33.
Fournier AK, Campbell LE, Castagnino P, Liu WF, Chung BM, Weaver VM, Chen CS, Assoian RK. PMID: 18187454; PMCID: PMC2662746.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Integrin-mediated signalling through the MAP-kinase pathway. IET Syst Biol. 2008 Jan; 2(1):8-15.
Yee KL, Weaver VM, Hammer DA. PMID: 18248081.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures. Annu Rev Pathol. 2008; 3:313-39.
Hebner C, Weaver VM, Debnath J. PMID: 18039125.
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PubMed Mentions:
62 Fields:
Translation:
HumansCells
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alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini. J Cell Sci. 2007 Oct 15; 120(Pt 20):3700-12.
Friedland JC, Lakins JN, Kazanietz MG, Chernoff J, Boettiger D, Weaver VM. PMID: 17911169.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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G'rab'bing the microenvironment for invasion. Dev Cell. 2007 Oct; 13(4):462-3.
Weaver V, Werb Z. PMID: 17925222.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. Int J Biochem Cell Biol. 2007; 39(11):1987-94.
Kass L, Erler JT, Dembo M, Weaver VM. PMID: 17719831; PMCID: PMC2658720.
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PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis. Methods Cell Biol. 2007; 83:547-83.
Johnson KR, Leight JL, Weaver VM. PMID: 17613324; PMCID: PMC2658721.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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The ultrastructure of MCF-10A acini. J Cell Physiol. 2006 Jul; 208(1):141-8.
Underwood JM, Imbalzano KM, Weaver VM, Fischer AH, Imbalzano AN, Nickerson JA. PMID: 16607610.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Forcing the third dimension. Cell. 2006 May 05; 125(3):429-31.
Boudreau N, Weaver V. PMID: 16678088.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard. J Proteome Res. 2005 Nov-Dec; 4(6):2007-14.
Yan Y, Weaver VM, Blair IA. PMID: 16335945.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Tensional homeostasis and the malignant phenotype. Cancer Cell. 2005 Sep; 8(3):241-54.
Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM. PMID: 16169468.
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PubMed Mentions:
1817 Fields:
Translation:
AnimalsCells
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Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin. J Biol Chem. 2005 Jul 01; 280(26):24363-70.
Yang C, Liu Y, Leskow FC, Weaver VM, Kazanietz MG. PMID: 15863513.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression. Mol Biol Cell. 2005 Apr; 16(4):1901-12.
Cowden Dahl KD, Robertson SE, Weaver VM, Simon MC. PMID: 15689487; PMCID: PMC1073670.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil Cytoskeleton. 2005 Jan; 60(1):24-34.
Yeung T, Georges PC, Flanagan LA, Marg B, Ortiz M, Funaki M, Zahir N, Ming W, Weaver V, Janmey PA. PMID: 15573414.
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PubMed Mentions:
832 Fields:
Translation:
HumansAnimalsCells
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The tension mounts: mechanics meets morphogenesis and malignancy. J Mammary Gland Biol Neoplasia. 2004 Oct; 9(4):325-42.
Paszek MJ, Weaver VM. PMID: 15838603.
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PubMed Mentions:
231 Fields:
Translation:
HumansAnimals
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Watch thy neighbor: cancer is a communal affair. J Cell Sci. 2004 Mar 15; 117(Pt 8):1287-90.
Weaver VM, Gilbert P. PMID: 15020668.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Death in the third dimension: apoptosis regulation and tissue architecture. Curr Opin Genet Dev. 2004 Feb; 14(1):71-80.
Zahir N, Weaver VM. PMID: 15108808.
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PubMed Mentions:
48 Fields:
Translation:
Cells
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Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors. J Cell Biol. 2003 Dec 22; 163(6):1397-407.
Zahir N, Lakins JN, Russell A, Ming W, Chatterjee C, Rozenberg GI, Marinkovich MP, Weaver VM. PMID: 14691145; PMCID: PMC2173718.
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PubMed Mentions:
80 Fields:
Translation:
HumansCells
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Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin. J Cell Sci. 2003 Sep 01; 116(Pt 17):3543-56.
Russell AJ, Fincher EF, Millman L, Smith R, Vela V, Waterman EA, Dey CN, Guide S, Weaver VM, Marinkovich MP. PMID: 12865436.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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The tissue microenvironment as an epigenetic tumor modifier. Methods Mol Biol. 2003; 223:315-47.
Unger M, Weaver VM. PMID: 12777739.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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The organizing principle: microenvironmental influences in the normal and malignant breast. Differentiation. 2002 Dec; 70(9-10):537-46.
Bissell MJ, Radisky DC, Rizki A, Weaver VM, Petersen OW. PMID: 12492495; PMCID: PMC2933198.
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PubMed Mentions:
252 Fields:
Translation:
HumansCells
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beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002 Sep; 2(3):205-16.
Weaver VM, Lelièvre S, Lakins JN, Chrenek MA, Jones JC, Giancotti F, Werb Z, Bissell MJ. PMID: 12242153; PMCID: PMC2788997.
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PubMed Mentions:
334 Fields:
Translation:
HumansCells
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Membrane-associated MMP regulators: novel cell adhesion tumor suppressor proteins? Dev Cell. 2002 Jan; 2(1):6-7.
Weaver VM. PMID: 11782309.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation. Breast Cancer Res. 2001; 3(4):224-9.
Chrenek MA, Wong P, Weaver VM. PMID: 11434873; PMCID: PMC138686.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Lack of specificity of trans,trans-muconic acid as a benzene biomarker after ingestion of sorbic acid-preserved foods. Cancer Epidemiol Biomarkers Prev. 2000 Jul; 9(7):749-55.
Weaver VM, Buckley T, Groopman JD. PMID: 10919747.
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PubMed Mentions:
18 Fields:
Translation:
HumansPHPublic Health
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E7-transduced human breast epithelial cells show partial differentiation in three-dimensional culture. Cancer Res. 1999 Dec 15; 59(24):6042-5.
Spancake KM, Anderson CB, Weaver VM, Matsunami N, Bissell MJ, White RL. PMID: 10626787.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Constitutive expression of Heregulin induces apoptosis in an erbB-2 overexpressing breast cancer cell line SKBr-3. Int J Oncol. 1999 Nov; 15(5):883-92.
Guerra-Vladusic FK, Scott G, Weaver V, Vladusic EA, Tsai MS, Benz CC, Lupu R. PMID: 10536169.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Functional culture models to study mechanisms governing apoptosis in normal and malignant mammary epithelial cells. J Mammary Gland Biol Neoplasia. 1999 Apr; 4(2):193-201.
Weaver VM, Bissell MJ. PMID: 10426398; PMCID: PMC2933214.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res. 1999 Apr 01; 59(7 Suppl):1757-1763s; discussion 1763s-1764s.
Bissell MJ, Weaver VM, Lelièvre SA, Wang F, Petersen OW, Schmeichel KL. PMID: 10197593.
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PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
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Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14711-6.
Lelièvre SA, Weaver VM, Nickerson JA, Larabell CA, Bhaumik A, Petersen OW, Bissell MJ. PMID: 9843954; PMCID: PMC24514.
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PubMed Mentions:
104 Fields:
Translation:
HumansCells
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Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14821-6.
Wang F, Weaver VM, Petersen OW, Larabell CA, Dedhar S, Briand P, Lupu R, Bissell MJ. PMID: 9843973; PMCID: PMC24533.
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PubMed Mentions:
270 Fields:
Translation:
HumansCells
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Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype. J Mammary Gland Biol Neoplasia. 1998 Apr; 3(2):201-13.
Schmeichel KL, Weaver VM, Bissell MJ. PMID: 10819528; PMCID: PMC2933208.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Differentiation and cancer in the mammary gland: shedding light on an old dichotomy. Adv Cancer Res. 1998; 75:135-61.
Petersen OW, Rønnov-Jessen L, Weaver VM, Bissell MJ. PMID: 9709809; PMCID: PMC3867313.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol. 1997 Apr 07; 137(1):231-45.
Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ. PMID: 9105051; PMCID: PMC2139858.
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PubMed Mentions:
619 Fields:
Translation:
HumansAnimalsCells
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Extracellular matrix: the central regulator of cell and tissue homeostasis. Trends Cell Biol. 1997 Jan; 7(1):40-2.
Weaver VM, Roskelley CD. PMID: 17708898.
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PubMed Mentions:
9 Fields:
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Extracellular matrix signaling from the cellular membrane skeleton to the nuclear skeleton: a model of gene regulation. Recent Prog Horm Res. 1996; 51:417-32.
Lelièvre S, Weaver VM, Bissell MJ. PMID: 8701089; PMCID: PMC2937008.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes. J Cell Sci. 1996 Jan; 109 ( Pt 1):45-56.
Weaver VM, Carson CE, Walker PR, Chaly N, Lach B, Raymond Y, Brown DL, Sikorska M. PMID: 8834789.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay. Biochem Cell Biol. 1996; 74(6):833-51.
Weaver VM, Fischer AH, Peterson OW, Bissell MJ. PMID: 9164652; PMCID: PMC2933195.
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PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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The development of a functionally relevant cell culture model of progressive human breast cancer. Semin Cancer Biol. 1995 Jun; 6(3):175-84.
Weaver VM, Howlett AR, Langton-Webster B, Petersen OW, Bissell MJ. PMID: 7495986.
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PubMed Mentions:
61 Fields:
Translation:
HumansCells
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Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes. Biochem Cell Biol. 1993 Sep-Oct; 71(9-10):488-500.
Weaver VM, Lach B, Walker PR, Sikorska M. PMID: 8192901.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells