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Victoria Rafalski, PhD

Title(s)Postdoctoral Scholar, Gladstone Institutes
SchoolSchool of Medicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Role of Fibrinogen in Neuronal Dysfunction
    NIH/NINDS F32NS096920Dec 1, 2016 - Nov 30, 2018
    Role: Principal Investigator
    The role of the deacetylase Sirt1 in the maintenance of adult neural stem cells
    NIH/NINDS F31NS064600Sep 15, 2008 - Sep 14, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, Mucke L, Nelson RB, Akassoglou K. Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model. Neuron. 2019 Mar 20; 101(6):1099-1108.e6. PMID: 30737131.
      View in: PubMed
    2. Ryu JK, Rafalski VA, Meyer-Franke A, Adams RA, Poda SB, Rios Coronado PE, Pedersen LØ, Menon V, Baeten KM, Sikorski SL, Bedard C, Hanspers K, Bardehle S, Mendiola AS, Davalos D, Machado MR, Chan JP, Plastira I, Petersen MA, Pfaff SJ, Ang KK, Hallenbeck KK, Syme C, Hakozaki H, Ellisman MH, Swanson RA, Zamvil SS, Arkin MR, Zorn SH, Pico AR, Mucke L, Freedman SB, Stavenhagen JB, Nelson RB, Akassoglou K. Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration. Nat Immunol. 2018 11; 19(11):1212-1223. PMID: 30323343.
      View in: PubMed
    3. Rafalski VA, Merlini M, Akassoglou K. Pericytes: The Brain's Very First Responders? Neuron. 2018 Oct 10; 100(1):11-13. PMID: 30308164.
      View in: PubMed
    4. Akassoglou K, Merlini M, Rafalski VA, Real R, Liang L, Jin Y, Dougherty SE, De Paola V, Linden DJ, Misgeld T, Zheng B. In Vivo Imaging of CNS Injury and Disease. J Neurosci. 2017 11 08; 37(45):10808-10816. PMID: 29118209.
      View in: PubMed
    5. Bardehle S, Rafalski V, Akassoglou K. Finding the 'ubiquitous' threads in infection and autoimmune neuroinflammation. Nat Immunol. 2016 12 16; 18(1):7-8. PMID: 27984564.
      View in: PubMed
    6. Bardehle S, Rafalski VA, Akassoglou K. Breaking boundaries-coagulation and fibrinolysis at the neurovascular interface. Front Cell Neurosci. 2015; 9:354. PMID: 26441525; PMCID: PMC4584986.
    7. Schachtrup C, Ryu JK, Mammadzada K, Khan AS, Carlton PM, Perez A, Christian F, Le Moan N, Vagena E, Baeza-Raja B, Rafalski V, Chan JP, Nitschke R, Houslay MD, Ellisman MH, Wyss-Coray T, Palop JJ, Akassoglou K. Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-ß signaling and astrocyte functions. Nat Neurosci. 2015 Aug; 18(8):1077-80. PMID: 26120963; PMCID: PMC4878404.
    8. Le Moan N, Baeten KM, Rafalski VA, Ryu JK, Rios Coronado PE, Bedard C, Syme C, Davalos D, Akassoglou K. Hypoxia Inducible Factor-1a in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease eNeuro. 2015 Mar-Apr; 2(2). PMID: 26213713.
      View in: PubMed
    9. Rafalski VA, Ho PP, Brett JO, Ucar D, Dugas JC, Pollina EA, Chow LM, Ibrahim A, Baker SJ, Barres BA, Steinman L, Brunet A. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat Cell Biol. 2013 Jun; 15(6):614-24. PMID: 23644469.
      View in: PubMed
    10. Rafalski VA, Mancini E, Brunet A. Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate. J Cell Sci. 2012 Dec 01; 125(Pt 23):5597-608. PMID: 23420198; PMCID: PMC3575699.
    11. Brett JO, Renault VM, Rafalski VA, Webb AE, Brunet A. The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. Aging (Albany NY). 2011 Feb; 3(2):108-24. PMID: 21386132; PMCID: PMC3082007.
    12. Rafalski VA, Brunet A. Energy metabolism in adult neural stem cell fate. Prog Neurobiol. 2011 Feb; 93(2):182-203. PMID: 21056618.
      View in: PubMed
    13. Renault VM, Rafalski VA, Morgan AA, Salih DA, Brett JO, Webb AE, Villeda SA, Thekkat PU, Guillerey C, Denko NC, Palmer TD, Butte AJ, Brunet A. FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell. 2009 Nov 06; 5(5):527-39. PMID: 19896443.
      View in: PubMed
    14. Bzdega T, Crowe SL, Ramadan ER, Sciarretta KH, Olszewski RT, Ojeifo OA, Rafalski VA, Wroblewska B, Neale JH. The cloning and characterization of a second brain enzyme with NAAG peptidase activity. J Neurochem. 2004 May; 89(3):627-35. PMID: 15086519.
      View in: PubMed