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Vivek Jain, MD, MAS

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-476-4082 ext. 355
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    Vivek Jain, M.D., M.A.S. is an Associate Professor of Medicine and Infectious Diseases in the Division of HIV, Infectious Diseases & Global Medicine at San Francisco General Hospital (SFGH) at the University of California, San Francisco.

    Dr. Jain is an infectious disease specialist focused on HIV, general infectious diseases, and internal medicine. He is the director of the SFGH Infectious Diseases Clinic, Co-Director of the SFGH Infection Control and Prevention Team, serves as an attending physician on the Infectious Diseases Consult Service, serves as an HIV-focused primary care doctor in the Positive Health Practice Clinic of SFGH, and is Co-director of the Communicable Diseases course in the UCSF Global Health Sciences Master's Degree program.

    Dr. Jain is helping lead the COVID-19 epidemic response at Zuckerberg San Francisco General Hospital, overseeing clinical and medical operations of the COVID-19 team, and working with hospital leadership on logistic and operational response elements. He is conducting research on the epidemiology of COVID-19 and therapeutic strategies to mitigate disease.

    Dr. Jain also conducts implementation science research on HIV antiretroviral therapy (ART) delivery in resource limited settings, working with collaborators at Makerere University and the Infectious Diseases Research Collaboration (IDRC) in Kampala, Uganda and in Kenya. The goal of this research is to develop, test and understand the optimal implementation of systems of care for HIV-positive persons in Sub-Saharan Africa. This includes early diagnosis of HIV, immediate/early treatment of HIV with antiretroviral therapy, and improving the use of HIV viral load and other infectious disease diagnostics for clinics and hospitals. Dr. Jain's research includes the EARLI Study (one of Africa's first studies of ART administration to individuals with high CD4+ T-cell counts), the SEARCH Study (a large cluster randomized trial of wide scale HIV testing and universal HIV ART in 32 communities in Uganda and Kenya), and the RAPID-VL Study (a cluster randomized trial of a novel combination intervention to optimize the way HIV viral load testing is performed in HIV clinics in Uganda).

    Dr. Jain earned his undergraduate degree in Biochemistry from Harvard University, followed by his M.D. from Stanford University School of Medicine. He completed residency, chief residency, and infectious diseases fellowship at UCSF, and an M.A.S. degree in clinical research also at UCSF.

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    RAPID-VL: Optimizing HIV Viral Load Monitoring and Outcomes for High-Risk Populations
    CDC U01GH002119Sep 30, 2016 - Sep 30, 2020
    Role: PI
    Early Antiretroviral Therapy in Patients with High CD4+ T Cell Counts in Resource Limited Settings (EARLI)
    Gilead Sciences Apr 1, 2012 - Apr 1, 2017
    Role: PI

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. HIV incidence after pre-exposure prophylaxis initiation among women and men at elevated HIV risk: A population-based study in rural Kenya and Uganda. PLoS Med. 2021 Feb; 18(2):e1003492. Koss CA, Havlir DV, Ayieko J, Kwarisiima D, Kabami J, Chamie G, Atukunda M, Mwinike Y, Mwangwa F, Owaraganise A, Peng J, Olilo W, Snyman K, Awuonda B, Clark TD, Black D, Nugent J, Brown LB, Marquez C, Okochi H, Zhang K, Camlin CS, Jain V, Gandhi M, Cohen CR, Bukusi EA, Charlebois ED, Petersen ML, Kamya MR, Balzer LB. PMID: 33561143.
      View in: PubMed   Mentions:    Fields:    
    2. Improved Viral Suppression With Streamlined Care in the SEARCH Study. J Acquir Immune Defic Syndr. 2020 Dec 15; 85(5):571-578. Hickey MD, Ayieko J, Kwarisiima D, Opel FJ, Owaraganise A, Balzer LB, Chamie G, Jain V, Peng J, Camlin C, Charlebois ED, Cohen CR, Bukusi EA, Kamya MR, Petersen ML, Havlir DV. PMID: 32991337.
      View in: PubMed   Mentions:    Fields:    
    3. Machine Learning to Identify Persons at High-Risk of Human Immunodeficiency Virus Acquisition in Rural Kenya and Uganda. Clin Infect Dis. 2020 Dec 03; 71(9):2326-2333. Balzer LB, Havlir DV, Kamya MR, Chamie G, Charlebois ED, Clark TD, Koss CA, Kwarisiima D, Ayieko J, Sang N, Kabami J, Atukunda M, Jain V, Camlin CS, Cohen CR, Bukusi EA, Van Der Laan M, Petersen ML. PMID: 31697383.
      View in: PubMed   Mentions: 6     Fields:    
    4. SARS-CoV-2 Community Transmission disproportionately affects Latinx population during Shelter-in-Place in San Francisco. Clin Infect Dis. 2020 Aug 21. Chamie G, Marquez C, Crawford E, Peng J, Petersen M, Schwab D, Schwab J, Martinez J, Es DJ, Black D, Gandhi M, Kerkhoff AD, Jain V, Sergi F, Jacobo J, Rojas S, Tulier-Laiwa V, Gallardo-Brown T, Appa A, Chiu C, Rodgers M, Hackett J, Kistler A, Hao S, Kamm J, Dynerman D, Batson J, Greenhouse B, DeRisi J, Havlir DV. PMID: 32821935.
      View in: PubMed   Mentions: 7     Fields:    
    5. Management and Outcomes of Critically-Ill Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series. medRxiv. 2020 May 29. Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, Auyeung V, Cattamanchi A, Hendrickson CM. PMID: 32511538.
      View in: PubMed   Mentions:
    6. Home-Based Outpatient Parenteral Antibiotic Therapy at an Urban Safety Net Hospital: Comparing Outcomes in Persons With and Without Noninjection Drug Use. Open Forum Infect Dis. 2020 May; 7(5):ofaa162. Appa A, Marquez C, Jain V. PMID: 32494584.
      View in: PubMed   Mentions:
    7. Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of observational data from the SEARCH study. Lancet HIV. 2020 04; 7(4):e249-e261. Koss CA, Charlebois ED, Ayieko J, Kwarisiima D, Kabami J, Balzer LB, Atukunda M, Mwangwa F, Peng J, Mwinike Y, Owaraganise A, Chamie G, Jain V, Sang N, Olilo W, Brown LB, Marquez C, Zhang K, Ruel TD, Camlin CS, Rooney JF, Black D, Clark TD, Gandhi M, Cohen CR, Bukusi EA, Petersen ML, Kamya MR, Havlir DV. PMID: 32087152.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    8. Hypertension testing and treatment in Uganda and Kenya through the SEARCH study: An implementation fidelity and outcome evaluation. PLoS One. 2020; 15(1):e0222801. Heller DJ, Balzer LB, Kazi D, Charlebois ED, Kwarisiima D, Mwangwa F, Jain V, Kotwani P, Chamie G, Cohen CR, Clark TD, Ayieko J, Byonanabye DM, Petersen M, Kamya MR, Havlir D, Kahn JG. PMID: 31940346.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    9. HIV Testing and Treatment with the Use of a Community Health Approach in Rural Africa. N Engl J Med. 2019 07 18; 381(3):219-229. Havlir DV, Balzer LB, Charlebois ED, Clark TD, Kwarisiima D, Ayieko J, Kabami J, Sang N, Liegler T, Chamie G, Camlin CS, Jain V, Kadede K, Atukunda M, Ruel T, Shade SB, Ssemmondo E, Byonanebye DM, Mwangwa F, Owaraganise A, Olilo W, Black D, Snyman K, Burger R, Getahun M, Achando J, Awuonda B, Nakato H, Kironde J, Okiror S, Thirumurthy H, Koss C, Brown L, Marquez C, Schwab J, Lavoy G, Plenty A, Mugoma Wafula E, Omanya P, Chen YH, Rooney JF, Bacon M, van der Laan M, Cohen CR, Bukusi E, Kamya MR, Petersen M. PMID: 31314966.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansPHPublic Health
    10. Predictors of isoniazid preventive therapy completion among HIV-infected patients receiving differentiated and non-differentiated HIV care in rural Uganda. AIDS Care. 2020 01; 32(1):119-127. Tram KH, Mwangwa F, Chamie G, Atukunda M, Owaraganise A, Ayieko J, Jain V, Clark TD, Kwarisiima D, Petersen ML, Kamya MR, Charlebois ED, Havlir DV, Marquez C. PMID: 31181961.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Hypertension control in integrated HIV and chronic disease clinics in Uganda in the SEARCH study. BMC Public Health. 2019 May 06; 19(1):511. Kwarisiima D, Atukunda M, Owaraganise A, Chamie G, Clark T, Kabami J, Jain V, Byonanebye D, Mwangwa F, Balzer LB, Charlebois E, Kamya MR, Petersen M, Havlir DV, Brown LB. PMID: 31060545.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    12. Costs of streamlined HIV care delivery in rural Ugandan and Kenyan clinics in the SEARCH Studys. AIDS. 2018 09 24; 32(15):2179-2188. Shade SB, Osmand T, Luo A, Aine R, Assurah E, Mwebaza B, Mwai D, Owaraganise A, Mwangwa F, Ayieko J, Black D, Brown LB, Clark TD, Kwarisiima D, Thirumurthy H, Cohen CR, Bukusi EA, Charlebois ED, Balzer L, Kamya MR, Petersen ML, Havlir DV, Jain V. PMID: 30134294.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    13. Predictors of Retention in HIV Care Among Youth (15-24) in a Universal Test-and-Treat Setting in Rural Kenya. . 2017 09 01; 76(1):e15-e18. Brown LB, Ayieko J, Mwangwa F, Owaraganise A, Kwarisiima D, Jain V, Ruel T, Clark T, Black D, Chamie G, Bukusi EA, Cohen CR, Kamya MR, Petersen ML, Charlebois ED, Havlir DV. PMID: 28394821.
      View in: PubMed   Mentions:
    14. High rates of viral suppression in adults and children with high CD4+ counts using a streamlined ART delivery model in the SEARCH trial in rural Uganda and Kenya. J Int AIDS Soc. 2017 07 21; 20(Suppl 4):21673. PMID: 28770596.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    15. HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication. J Infect Dis. 2017 07 01; 216(1):72-81. PMID: 28498985.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Association of Implementation of a Universal Testing and Treatment Intervention With HIV Diagnosis, Receipt of Antiretroviral Therapy, and Viral Suppression in East Africa. JAMA. 2017 Jun 06; 317(21):2196-2206. PMID: 28586888.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    17. Population levels and geographical distribution of HIV RNA in rural Ugandan and Kenyan communities, including serodiscordant couples: a cross-sectional analysis. Lancet HIV. 2017 03; 4(3):e122-e133. PMID: 27989576.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    18. High levels of retention in care with streamlined care and universal test and treat in East Africa. AIDS. 2016 11 28; 30(18):2855-2864. PMID: 27603290.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    19. Immunologic profiles distinguish aviremic HIV-infected adults. AIDS. 2016 06 19; 30(10):1553-62. PMID: 26854811.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    20. Population-Based Assessment of Hypertension Epidemiology and Risk Factors among HIV-Positive and General Populations in Rural Uganda. PLoS One. 2016; 11(5):e0156309. PMID: 27232186.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    21. A hybrid mobile approach for population-wide HIV testing in rural east Africa: an observational study. Lancet HIV. 2016 Mar; 3(3):e111-9. PMID: 26939734.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansPHPublic Health
    22. Estimated Costs for Delivery of HIV Antiretroviral Therapy to Individuals with CD4+ T-Cell Counts >350 cells/uL in Rural Uganda. PLoS One. 2015; 10(12):e0143433. PMID: 26632823.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    23. Daptomycin non-susceptible, vancomycin-intermediate Staphylococcus aureus endocarditis treated with ceftaroline and daptomycin: case report and brief review of the literature. Infection. 2015 Dec; 43(6):751-4. PMID: 25805524.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    24. Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+ T-cell counts above 350 cells/µl in rural Uganda. AIDS. 2014 Sep 24; 28(15):2241-9. PMID: 25022596.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    25. Programmed death-1 expression on CD4? and CD8? T cells in treated and untreated HIV disease. AIDS. 2014 Jul 31; 28(12):1749-58. PMID: 24871455.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    26. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. PLoS Pathog. 2014 May; 10(5):e1004078. PMID: 24831517.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansCells
    27. Lymphogranuloma venereum causing a persistent genital ulcer. Sex Transm Dis. 2014 Apr; 41(4):280-2. PMID: 24622642.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Changes in population HIV RNA levels in Mbarara, Uganda, during scale-up of HIV antiretroviral therapy access. . 2014 Mar 01; 65(3):327-32. PMID: 24146022.
      View in: PubMed   Mentions:
    29. Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection. J Infect Dis. 2014 Aug 01; 210(3):374-82. PMID: 24585893.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    30. Evaluating linkage to care for hypertension after community-based screening in rural Uganda. Trop Med Int Health. 2014 Apr; 19(4):459-68. PMID: 24495307.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansPHPublic Health
    31. Uptake of community-based HIV testing during a multi-disease health campaign in rural Uganda. PLoS One. 2014; 9(1):e84317. PMID: 24392124.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansPHPublic Health
    32. Epidemiology and awareness of hypertension in a rural Ugandan community: a cross-sectional study. BMC Public Health. 2013 Dec 09; 13:1151. PMID: 24321133.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    33. High retention in care among HIV-infected patients entering care with CD4 levels >350 cells/µL under routine program conditions in Uganda. Clin Infect Dis. 2013 Nov; 57(9):1343-50. PMID: 23899683.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    34. Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. J Infect Dis. 2013 Oct 15; 208(8):1202-11. PMID: 23852127.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansCells
    35. Improved employment and education outcomes in households of HIV-infected adults with high CD4 cell counts: evidence from a community health campaign in Uganda. AIDS. 2013 Feb 20; 27(4):627-34. PMID: 23169332.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    36. Assessment of population-based HIV RNA levels in a rural east African setting using a fingerprick-based blood collection method. Clin Infect Dis. 2013 Feb; 56(4):598-605. PMID: 23243180.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    37. Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells. J Infect Dis. 2013 Jul; 208(1):50-6. PMID: 23089590.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    38. The effect of a "universal antiretroviral therapy" recommendation on HIV RNA levels among HIV-infected patients entering care with a CD4 count greater than 500/µL in a public health setting. Clin Infect Dis. 2012 Dec; 55(12):1690-7. PMID: 22955429.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsPHPublic Health
    39. Leveraging rapid community-based HIV testing campaigns for non-communicable diseases in rural Uganda. PLoS One. 2012; 7(8):e43400. PMID: 22916256.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    40. Differential persistence of transmitted HIV-1 drug resistance mutation classes. J Infect Dis. 2011 Apr 15; 203(8):1174-81. Jain V, Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Janini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM. PMID: 21451005.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    41. Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009. PLoS One. 2010 Dec 10; 5(12):e15510. PMID: 21170322.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    42. When to start antiretroviral therapy. Curr HIV/AIDS Rep. 2010 May; 7(2):60-8. Jain V, Deeks SG. PMID: 20425559.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    43. Early versus deferred antiretroviral therapy for HIV. N Engl J Med. 2009 Aug 20; 361(8):822; author reply 823-4. Buchbinder SP, Jain V. PMID: 19692695.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Infective endocarditis in an urban medical center: association of individual drugs with valvular involvement. J Infect. 2008 Aug; 57(2):132-8. Jain V, Yang MH, Kovacicova-Lezcano G, Juhle LS, Bolger AF, Winston LG. PMID: 18597851.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    45. Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs. J Infect Dis. 2005 Sep 01; 192 Suppl 1:S146-59. Gentsch JR, Laird AR, Bielfelt B, Griffin DD, Banyai K, Ramachandran M, Jain V, Cunliffe NA, Nakagomi O, Kirkwood CD, Fischer TK, Parashar UD, Bresee JS, Jiang B, Glass RI. PMID: 16088798.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    46. Assessment of the epidemic potential of a new strain of rotavirus associated with the novel G9 serotype which caused an outbreak in the United States for the first time in the 1995-1996 season. J Clin Microbiol. 2004 Apr; 42(4):1434-8. Clark HF, Lawley DA, Schaffer A, Patacsil JM, Marcello AE, Glass RI, Jain V, Gentsch J. PMID: 15070985.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsPHPublic Health
    47. Pediatric surgical emergencies in the setting of a natural disaster: Experiences from the 2001 earthquake in Gujarat, India. J Pediatr Surg. 2003 May; 38(5):663-7. Jain V, Noponen R, Smith BM. PMID: 12720165.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    48. Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering. Nat Struct Biol. 2003 Jan; 10(1):38-44. Davis S, Papadopoulos N, Aldrich TH, Maisonpierre PC, Huang T, Kovac L, Xu A, Leidich R, Radziejewska E, Rafique A, Goldberg J, Jain V, Bailey K, Karow M, Fandl J, Samuelsson SJ, Ioffe E, Rudge JS, Daly TJ, Radziejewski C, Yancopoulos GD. PMID: 12469114.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    49. Great diversity of group A rotavirus strains and high prevalence of mixed rotavirus infections in India. J Clin Microbiol. 2001 Oct; 39(10):3524-9. Jain V, Das BK, Bhan MK, Glass RI, Gentsch JR. PMID: 11574567.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    50. Epidemiology of rotavirus in India. Indian J Pediatr. 2001 Sep; 68(9):855-62. Jain V, Parashar UD, Glass RI, Bhan MK. PMID: 11669034.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    51. Use of lambda phage S and R gene products in an inducible lysis system for Vibrio cholerae- and Salmonella enterica serovar typhimurium-based DNA vaccine delivery systems. Infect Immun. 2000 Feb; 68(2):986-9. Jain V, Mekalanos JJ. PMID: 10639478.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    52. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell. 1996 Dec 27; 87(7):1161-9. Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Maisonpierre PC, Yancopoulos GD. PMID: 8980223.
      View in: PubMed   Mentions: 428     Fields:    Translation:HumansAnimalsCells
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