Xiaojuan Li, PhD

TitleEmployee of Affiliated Org.
InstitutionUniversity of California San Francisco
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPh.D.2003 Graduate Division (Bioengineering)
    Collapse Awards and Honors
    Academy of Radiology Research2015Distinguished Investigator Award
    ISMRM2012Distinguished MRM reviewer
    JOSPT George J. Davies2012James A. Gould Excellence in Clinical Inquiry Award (Co-author)
    ASBMR2011ASBMR Annual Meeting President’s Poster Competition Winner (Second Author)
    Skeletal Radiology2010Editor Award (Corresponding Author)
    AAOS/ORS2008Young Investigator, AAOS/ORS Research Symposium
    Inter Osteoporosis Conf. - Bone and Joint Decade2007Outstanding Paper Award
    NIH/NIAMS2006Mentored Quantitative Research Career Development Award
    Orthopaedic Research Society2006New Investigator Recognition Finalist
    ISMRM2001  - 2003Student Conference Travel Award
    University of California, Berkeley1999  - 2000Regents Fellowship
    Tsinghua University1992  - 1999Outstanding Student Scholarship

    Collapse Overview 
    Collapse Overview
    Xiaojaun Li, PhD, is a Professor in Residence in the Musculoskeletal Quantitative Imaging Research Group in the Department of Radiology and Biomedical, the Department of Orthopaedic Surgery, the Joint Bioengineering Graduate Program by UC-Berkeley and UCSF, and she is the Director of the Arthritis Imaging Laboratory at the University of California, San Francisco. She received her BS in Biomedical Engineering from Tsinghua University, China in 1996, and she completed her MS in Biomedical Engineering from Tsinghua University in 1999. Dr. Li obtained her PhD in Bioengineering from UCSF in 2003, followed by a postdoctoral research fellowship from UCSF in 2004.

    Dr. Li’s research program aims to develop advanced quantitative MRI and MRSI imaging techniques, and evaluating their clinical significance for musculoskeletal diseases such as arthritis, acute knee injuries, and osteoporosis. Her research projects include detecting early cartilage degeneration in osteoarthritis, imaging acutely ACL-injured knees, correlating MR imaging with biochemical, molecular and biomechanical in degenerated cartilage, multimodality imaging of rheumatoid arthritis, bone marrow fat and bone quality, intromyocellular lipids quantification, and lipid and osteoarthritis.

    Presently, Dr. Li is a member of 6 societies and she serves as a reviewer for more than 17 scientific journals as well as a charter member for NIH study section and a grant reviewer for other national and international institutes. Dr. Li has been award several NIH research grants, and she has published more than 100 peer-reviewed journal articles, 5 book chapters and more than 200 conference abstracts related to her research.

    Musculoskeletal Imaging

    MR techniques, musculoskeletal applications, arthritis, marrow adiposity

    Professional Interests:
    Advanced medical imaging, MRI, MR spectroscopic imaging, clinically oriented quantitative imaging, cartilage degeneration, osteoarthritis, joint injury, lower back pain, rheumatoid arthritis (MRI and HR-pQCT), marrow adiposity and osteoporosis

    Education and Training:
    • Bachelor of Science: Tsinghua University, China - Biomedical Engineering
    • Masters of Science: Tsinghua University, China - Biomedical Engineering
    • Doctor of Philosophy: University of California, Berkeley - Bioengineering
    • Doctor of Philosophy: University of California, San Francisco - Bioengineering
    • Postdoctoral Research Fellowship: University of California, San Francisco

    Collapse Research 
    Collapse Research Activities and Funding
    Enhanced MR for morphological characterization of ligaments, tendons and bone
    NIH/NIBIB U01EB023829May 1, 2018 - Jan 31, 2023
    Role: Co-Principal Investigator
    Longitudinal changes in marrow fat, other fat depots and bone
    NIH/NIAMS R01AR065645Jun 1, 2014 - May 31, 2018
    Role: Co-Principal Investigator
    Translation of Quantitative Imaging in Osteoarthritis
    NIH/NIAMS P50AR060752Aug 1, 2011 - Jul 31, 2016
    Role: Co-Investigator
    Bone Marrow Adiposity, Bone and Body Composition
    NIH/NIAMS R01AR057819Apr 1, 2010 - Mar 31, 2014
    Role: Co-Principal Investigator
    NMR Spectral Markers of Cartilage Degeneration in Osteoarthritis
    NIH/NIAMS R21AR056773Aug 1, 2009 - Jul 31, 2012
    Role: Principal Investigator
    In Vivo Early Detection of Cartilage Degeneration Using High Field MRI
    NIH/NIAMS K25AR053633Apr 12, 2006 - Mar 31, 2012
    Role: Principal Investigator

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    Collapse Clinical Trials
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    Collapse In The News
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Li X, Shet K, Xu K, Rodríguez JP, Pino AM, Kurhanewicz J, Schwartz A, Rosen CJ. Unsaturation level decreased in bone marrow fat of postmenopausal women with low bone density using high resolution magic angle spinning (HRMAS) 1H NMR spectroscopy. Bone. 2017 Dec; 105:87-92. PMID: 28823880.
      View in: PubMed
    2. Su F, Pedoia V, Teng HL, Kretzschmar M, Lau BC, McCulloch CE, Link TM, Ma CB, Li X. The association between MR T1? and T2 of cartilage and patient-reported outcomes after ACL injury and reconstruction. Osteoarthritis Cartilage. 2016 Jul; 24(7):1180-9. PMID: 26850823.
      View in: PubMed
    3. Tufts LS, Shet K, Liang F, Majumdar S, Li X. Quantification of bone marrow water and lipid composition in anterior cruciate ligament-injured and osteoarthritic knees using three-dimensional magnetic resonance spectroscopic imaging. Magn Reson Imaging. 2016 06; 34(5):632-7. PMID: 26723848; PMCID: PMC4860057 [Available on 06/01/17].
    4. Wang A, Pedoia V, Su F, Abramson E, Kretzschmar M, Nardo L, Link TM, McCulloch CE, Jin C, Ma CB, Li X. MR T1? and T2 of meniscus after acute anterior cruciate ligament injuries. Osteoarthritis Cartilage. 2016 Apr; 24(4):631-9. PMID: 26620091.
      View in: PubMed
    5. Liu J, Pedoia V, Heilmeier U, Ku E, Su F, Khanna S, Imboden J, Graf J, Link T, Li X. High-temporospatial-resolution dynamic contrast-enhanced (DCE) wrist MRI with variable-density pseudo-random circular Cartesian undersampling (CIRCUS) acquisition: evaluation of perfusion in rheumatoid arthritis patients. NMR Biomed. 2016 Jan; 29(1):15-23. PMID: 26608949; PMCID: PMC4724417 [Available on 01/01/17].
    6. Pedoia V, Li X, Su F, Calixto N, Majumdar S. Fully automatic analysis of the knee articular cartilage T1? relaxation time using voxel-based relaxometry. J Magn Reson Imaging. 2016 Apr; 43(4):970-80. PMID: 26443990; PMCID: PMC5018211 [Available on 04/01/17].
    7. Calixto NE, Kumar D, Subburaj K, Singh J, Schooler J, Nardo L, Li X, Souza RB, Link TM, Majumdar S. Zonal differences in meniscus MR relaxation times in response to in vivo static loading in knee osteoarthritis. J Orthop Res. 2016 Feb; 34(2):249-61. PMID: 26223430.
      View in: PubMed
    8. Kumar D, Souza RB, Subburaj K, MacLeod TD, Singh J, Calixto NE, Nardo L, Link TM, Li X, Lane NE, Majumdar S. Are There Sex Differences in Knee Cartilage Composition and Walking Mechanics in Healthy and Osteoarthritis Populations? Clin Orthop Relat Res. 2015 Aug; 473(8):2548-58. PMID: 25716211; PMCID: PMC4488198.
    9. Li X, Pedoia V, Kumar D, Rivoire J, Wyatt C, Lansdown D, Amano K, Okazaki N, Savic D, Koff MF, Felmlee J, Williams SL, Majumdar S. Cartilage T1? and T2 relaxation times: longitudinal reproducibility and variations using different coils, MR systems and sites. Osteoarthritis Cartilage. 2015 Dec; 23(12):2214-2223. PMID: 26187574; PMCID: PMC4663102 [Available on 12/01/16].
    10. Pedoia V, Lansdown DA, Zaid M, McCulloch CE, Souza R, Ma CB, Li X. Three-dimensional MRI-based statistical shape model and application to a cohort of knees with acute ACL injury. Osteoarthritis Cartilage. 2015 Oct; 23(10):1695-703. PMID: 26050865; PMCID: PMC5019115 [Available on 10/01/16].
    11. Zhou Y, Pandit P, Pedoia V, Rivoire J, Wang Y, Liang D, Li X, Ying L. Accelerating T1? cartilage imaging using compressed sensing with iterative locally adapted support detection and JSENSE. Magn Reson Med. 2016 Apr; 75(4):1617-29. PMID: 26010735; PMCID: PMC4834045 [Available on 04/01/17].
    12. Zaid M, Lansdown D, Su F, Pedoia V, Tufts L, Rizzo S, Souza RB, Li X, Ma CB. Abnormal tibial position is correlated to early degenerative changes one year following ACL reconstruction. J Orthop Res. 2015 Jul; 33(7):1079-86. PMID: 25721417.
      View in: PubMed
    13. Pandit P, Rivoire J, King K, Li X. Accelerated T1? acquisition for knee cartilage quantification using compressed sensing and data-driven parallel imaging: A feasibility study. Magn Reson Med. 2016 Mar; 75(3):1256-61. PMID: 25885368; PMCID: PMC4609215 [Available on 03/01/17].
    14. Yang H, Yu A, Burghardt AJ, Virayavanich W, Link TM, Imboden JB, Li X. Quantitative characterization of metacarpal and radial bone in rheumatoid arthritis using high resolution- peripheral quantitative computed tomography. Int J Rheum Dis. 2017 Mar; 20(3):353-362. PMID: 25865349.
      View in: PubMed
    15. Tufts L, Shet Vishnudas K, Fu E, Kurhanewicz J, Ries M, Alliston T, Li X. Correlating high-resolution magic angle spinning NMR spectroscopy and gene analysis in osteoarthritic cartilage. NMR Biomed. 2015 May; 28(5):523-8. PMID: 25761416; PMCID: PMC4400260.
    16. Schafer AL, Li X, Schwartz AV, Tufts LS, Wheeler AL, Grunfeld C, Stewart L, Rogers SJ, Carter JT, Posselt AM, Black DM, Shoback DM. Changes in vertebral bone marrow fat and bone mass after gastric bypass surgery: A pilot study. Bone. 2015 May; 74:140-5. PMID: 25603463; PMCID: PMC4355193.
    17. Lansdown DA, Zaid M, Pedoia V, Subburaj K, Souza R, Benjamin C, Li X. Reproducibility measurements of three methods for calculating in vivo MR-based knee kinematics. J Magn Reson Imaging. 2015 Aug; 42(2):533-8. PMID: 25545617; PMCID: PMC4485602.
    18. Lansdown DA, Allen C, Zaid M, Wu S, Subburaj K, Souza R, Feeley BT, Li X, Ma CB. A comprehensive in vivo kinematic, quantitative MRI and functional evaluation following ACL reconstruction--A comparison between mini-two incision and anteromedial portal femoral tunnel drilling. Knee. 2015 Dec; 22(6):547-53. PMID: 25982298; PMCID: PMC4472567 [Available on 12/01/16].
    19. Yang H, Rivoire J, Hoppe M, Srikhum W, Imboden J, Link TM, Li X. Computer-aided and manual quantifications of MRI synovitis, bone marrow edema-like lesions, erosion and cartilage loss in rheumatoid arthritis of the wrist. Skeletal Radiol. 2015 Apr; 44(4):539-47. PMID: 25488101.
      View in: PubMed
    20. Ma YH, Schwartz AV, Sigurdsson S, Hue TF, Lang TF, Harris TB, Rosen CJ, Vittinghoff E, Eiriksdottir G, Hauksdottir AM, Siggeirsdottir K, Sigurdsson G, Oskarsdottir D, Napoli N, Palermo L, Gudnason V, Li X. Circulating sclerostin associated with vertebral bone marrow fat in older men but not women. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2584-90. PMID: 25144629; PMCID: PMC4255105.
    21. Kumar D, Souza RB, Singh J, Calixto NE, Nardo L, Link TM, Li X, Majumdar S. Physical activity and spatial differences in medial knee T1rho and t2 relaxation times in knee osteoarthritis. J Orthop Sports Phys Ther. 2014 Dec; 44(12):964-72. PMID: 25353261; PMCID: PMC4476033.
    22. Lee CH, Srikhum W, Burghardt AJ, Virayavanich W, Imboden JB, Link TM, Li X. Correlation of structural abnormalities of the wrist and metacarpophalangeal joints evaluated by high-resolution peripheral quantitative computed tomography, 3 Tesla magnetic resonance imaging and conventional radiographs in rheumatoid arthritis. Int J Rheum Dis. 2015 Jul; 18(6):628-39. PMID: 25293500.
      View in: PubMed
    23. Gupta R, Virayavanich W, Kuo D, Su F, Link T, Ma B, Li X. MR T(1)? quantification of cartilage focal lesions in acutely injured knees: correlation with arthroscopic evaluation. Magn Reson Imaging. 2014 Dec; 32(10):1290-6. PMID: 25111625; PMCID: PMC4253653.
    24. Teruel JR, Burghardt AJ, Rivoire J, Srikhum W, Noworolski SM, Link TM, Imboden JB, Li X. Bone structure and perfusion quantification of bone marrow edema pattern in the wrist of patients with rheumatoid arthritis: a multimodality study. J Rheumatol. 2014 Sep; 41(9):1766-73. PMID: 25086074.
      View in: PubMed
    25. Kumar D, Kothari A, Souza RB, Wu S, Benjamin Ma C, Li X. Frontal plane knee mechanics and medial cartilage MR relaxation times in individuals with ACL reconstruction: A pilot study. Knee. 2014 Oct; 21(5):881-5. PMID: 24993277; PMCID: PMC4175149.
    26. Jungmann PM, Baum T, Bauer JS, Karampinos DC, Erdle B, Link TM, Li X, Trattnig S, Rummeny EJ, Woertler K, Welsch GH. Cartilage repair surgery: outcome evaluation by using noninvasive cartilage biomarkers based on quantitative MRI techniques? Biomed Res Int. 2014; 2014:840170. PMID: 24877139; PMCID: PMC4024422.
    27. Souza RB, Kumar D, Calixto N, Singh J, Schooler J, Subburaj K, Li X, Link TM, Majumdar S. Response of knee cartilage T1rho and T2 relaxation times to in vivo mechanical loading in individuals with and without knee osteoarthritis. Osteoarthritis Cartilage. 2014 Oct; 22(10):1367-76. PMID: 24792208.
      View in: PubMed
    28. Kumar D, Karampinos DC, MacLeod TD, Lin W, Nardo L, Li X, Link TM, Majumdar S, Souza RB. Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis. Osteoarthritis Cartilage. 2014 Feb; 22(2):226-34. PMID: 24361743; PMCID: PMC3932784.
    29. Subburaj K, Souza RB, Wyman BT, Le Graverand-Gastineau MP, Li X, Link TM, Majumdar S. Changes in MR relaxation times of the meniscus with acute loading: an in vivo pilot study in knee osteoarthritis. J Magn Reson Imaging. 2015 Feb; 41(2):536-43. PMID: 24347310; PMCID: PMC4062611.
    30. Schooler J, Kumar D, Nardo L, McCulloch C, Li X, Link TM, Majumdar S. Longitudinal evaluation of T1? and T2 spatial distribution in osteoarthritic and healthy medial knee cartilage. Osteoarthritis Cartilage. 2014 Jan; 22(1):51-62. PMID: 24188868; PMCID: PMC3934359.
    31. Kumar D, Subburaj K, Lin W, Karampinos DC, McCulloch CE, Li X, Link TM, Souza RB, Majumdar S. Quadriceps and hamstrings morphology is related to walking mechanics and knee cartilage MRI relaxation times in young adults. J Orthop Sports Phys Ther. 2013 Dec; 43(12):881-90. PMID: 24175607; PMCID: PMC4476495.
    32. Li X, Majumdar S. Quantitative MRI of articular cartilage and its clinical applications. J Magn Reson Imaging. 2013 Nov; 38(5):991-1008. PMID: 24115571; PMCID: PMC3858854.
    33. Patsch JM, Li X, Baum T, Yap SP, Karampinos DC, Schwartz AV, Link TM. Bone marrow fat composition as a novel imaging biomarker in postmenopausal women with prevalent fragility fractures. J Bone Miner Res. 2013 Aug; 28(8):1721-8. PMID: 23558967; PMCID: PMC3720702.
    34. Li X, Wyatt C, Rivoire J, Han E, Chen W, Schooler J, Liang F, Shet K, Souza R, Majumdar S. Simultaneous acquisition of T1? and T2 quantification in knee cartilage: repeatability and diurnal variation. J Magn Reson Imaging. 2014 May; 39(5):1287-93. PMID: 23897756; PMCID: PMC3844010.
    35. Burghardt AJ, Lee CH, Kuo D, Majumdar S, Imboden JB, Link TM, Li X. Quantitative in vivo HR-pQCT imaging of 3D wrist and metacarpophalangeal joint space width in rheumatoid arthritis. Ann Biomed Eng. 2013 Dec; 41(12):2553-64. PMID: 23887879; PMCID: PMC3823828.
    36. Thuillier DU, Souza RB, Wu S, Luke A, Li X, Feeley BT. T1? imaging demonstrates early changes in the lateral patella in patients with patellofemoral pain and maltracking. Am J Sports Med. 2013 Aug; 41(8):1813-8. PMID: 23845401.
      View in: PubMed
    37. Su F, Hilton JF, Nardo L, Wu S, Liang F, Link TM, Ma CB, Li X. Cartilage morphology and T1? and T2 quantification in ACL-reconstructed knees: a 2-year follow-up. Osteoarthritis Cartilage. 2013 Aug; 21(8):1058-67. PMID: 23707754; PMCID: PMC3752987.
    38. Subburaj K, Valentinitsch A, Dillon AB, Joseph GB, Li X, Link TM, Vail TP, Majumdar S. Regional variations in MR relaxation of hip joint cartilage in subjects with and without femoralacetabular impingement. Magn Reson Imaging. 2013 Sep; 31(7):1129-36. PMID: 23684960; PMCID: PMC3729918.
    39. Schwartz AV, Sigurdsson S, Hue TF, Lang TF, Harris TB, Rosen CJ, Vittinghoff E, Siggeirsdottir K, Sigurdsson G, Oskarsdottir D, Shet K, Palermo L, Gudnason V, Li X. Vertebral bone marrow fat associated with lower trabecular BMD and prevalent vertebral fracture in older adults. J Clin Endocrinol Metab. 2013 Jun; 98(6):2294-300. PMID: 23553860; PMCID: PMC3667265.
    40. Srikhum W, Virayavanich W, Burghardt AJ, Yu A, Link TM, Imboden JB, Li X. Quantitative and semiquantitative bone erosion assessment on high-resolution peripheral quantitative computed tomography in rheumatoid arthritis. J Rheumatol. 2013 Apr; 40(4):408-16. PMID: 23418386.
      View in: PubMed
    41. Theologis AA, Haughom B, Liang F, Zhang Y, Majumdar S, Link TM, Ma CB, Li X. Comparison of T1rho relaxation times between ACL-reconstructed knees and contralateral uninjured knees. Knee Surg Sports Traumatol Arthrosc. 2014 Feb; 22(2):298-307. PMID: 23370983; PMCID: PMC3692610.
    42. Souza RB, Feeley BT, Zarins ZA, Link TM, Li X, Majumdar S. T1rho MRI relaxation in knee OA subjects with varying sizes of cartilage lesions. Knee. 2013 Mar; 20(2):113-9. PMID: 23159719; PMCID: PMC3568198.
    43. Jungmann PM, Li X, Nardo L, Subburaj K, Lin W, Ma CB, Majumdar S, Link TM. Do cartilage repair procedures prevent degenerative meniscus changes?: longitudinal t1? and morphological evaluation with 3.0-T MRI. Am J Sports Med. 2012 Dec; 40(12):2700-8. PMID: 23104606; PMCID: PMC4074395.
    44. Kumar D, Schooler J, Zuo J, McCulloch CE, Nardo L, Link TM, Li X, Majumdar S. Trabecular bone structure and spatial differences in articular cartilage MR relaxation times in individuals with posterior horn medial meniscal tears. Osteoarthritis Cartilage. 2013 Jan; 21(1):86-93. PMID: 23047010; PMCID: PMC3538917.
    45. Kazakia GJ, Kuo D, Schooler J, Siddiqui S, Shanbhag S, Bernstein G, Horvai A, Majumdar S, Ries M, Li X. Bone and cartilage demonstrate changes localized to bone marrow edema-like lesions within osteoarthritic knees. Osteoarthritis Cartilage. 2013 Jan; 21(1):94-101. PMID: 23025926.
      View in: PubMed
    46. Jobke B, Bolbos R, Saadat E, Cheng J, Li X, Majumdar S. Mechanism of disease in early osteoarthritis: application of modern MR imaging techniques -- a technical report. Magn Reson Imaging. 2013 Jan; 31(1):156-61. PMID: 22902064; PMCID: PMC3504629.
    47. Stehling C, Souza RB, Hellio Le Graverand MP, Wyman BT, Li X, Majumdar S, Link TM. Loading of the knee during 3.0T MRI is associated with significantly increased medial meniscus extrusion in mild and moderate osteoarthritis. Eur J Radiol. 2012 Aug; 81(8):1839-45. PMID: 21684704; PMCID: PMC3399044.
    48. Subburaj K, Kumar D, Souza RB, Alizai H, Li X, Link TM, Majumdar S. The acute effect of running on knee articular cartilage and meniscus magnetic resonance relaxation times in young healthy adults. Am J Sports Med. 2012 Sep; 40(9):2134-41. PMID: 22729505; PMCID: PMC3660554.
    49. Souza RB, Baum T, Wu S, Feeley BT, Kadel N, Li X, Link TM, Majumdar S. Effects of unloading on knee articular cartilage T1rho and T2 magnetic resonance imaging relaxation times: a case series. J Orthop Sports Phys Ther. 2012 Jun; 42(6):511-20. PMID: 22402583; PMCID: PMC3673554.
    50. Jones EF, Schooler J, Miller DC, Drake CR, Wahnishe H, Siddiqui S, Li X, Majumdar S. Characterization of human osteoarthritic cartilage using optical and magnetic resonance imaging. Mol Imaging Biol. 2012 Feb; 14(1):32-9. PMID: 21384207; PMCID: PMC3258397.
    51. Zuo J, Joseph GB, Li X, Link TM, Hu SS, Berven SH, Kurhanewitz J, Majumdar S. In vivo intervertebral disc characterization using magnetic resonance spectroscopy and T1? imaging: association with discography and Oswestry Disability Index and Short Form-36 Health Survey. Spine (Phila Pa 1976). 2012 Feb 01; 37(3):214-21. PMID: 21697767; PMCID: PMC3633556.
    52. Kothari A, Haughom B, Subburaj K, Feeley B, Li X, Ma CB. Evaluating rotational kinematics of the knee in ACL reconstructed patients using 3.0 Tesla magnetic resonance imaging. Knee. 2012 Oct; 19(5):648-51. PMID: 22264714.
      View in: PubMed
    53. Haughom BD, Souza R, Schairer WW, Li X, Ma CB. Evaluating rotational kinematics of the knee in ACL-ruptured and healthy patients using 3.0 Tesla magnetic resonance imaging. Knee Surg Sports Traumatol Arthrosc. 2012 Apr; 20(4):663-70. PMID: 22159520.
      View in: PubMed
    54. Subburaj K, Souza RB, Stehling C, Wyman BT, Le Graverand-Gastineau MP, Link TM, Li X, Majumdar S. Association of MR relaxation and cartilage deformation in knee osteoarthritis. J Orthop Res. 2012 Jun; 30(6):919-26. PMID: 22161783; PMCID: PMC3652010.
    55. Souza RB, Fang C, Luke A, Wu S, Li X, Majumdar S. Relationship between knee kinetics during jumping tasks and knee articular cartilage MRI T1rho and T2 relaxation times. Clin Biomech (Bristol, Avon). 2012 May; 27(4):403-8. PMID: 22115848; PMCID: PMC3327363.
    56. Theologis AA, Schairer WW, Carballido-Gamio J, Majumdar S, Li X, Ma CB. Longitudinal analysis of T1? and T2 quantitative MRI of knee cartilage laminar organization following microfracture surgery. Knee. 2012 Oct; 19(5):652-7. PMID: 22018879; PMCID: PMC3652011.
    57. Li X, Yu A, Virayavanich W, Noworolski SM, Link TM, Imboden J. Quantitative characterization of bone marrow edema pattern in rheumatoid arthritis using 3 Tesla MRI. J Magn Reson Imaging. 2012 Jan; 35(1):211-7. PMID: 21987483.
      View in: PubMed
    58. Schairer WW, Haughom BD, Morse LJ, Li X, Ma CB. Magnetic resonance imaging evaluation of knee kinematics after anterior cruciate ligament reconstruction with anteromedial and transtibial femoral tunnel drilling techniques. Arthroscopy. 2011 Dec; 27(12):1663-70. PMID: 21958672.
      View in: PubMed
    59. Shet K, Siddiqui SM, Yoshihara H, Kurhanewicz J, Ries M, Li X. High-resolution magic angle spinning NMR spectroscopy of human osteoarthritic cartilage. NMR Biomed. 2012 Apr; 25(4):538-44. PMID: 21850648; PMCID: PMC3299852.
    60. Baum T, Yap SP, Karampinos DC, Nardo L, Kuo D, Burghardt AJ, Masharani UB, Schwartz AV, Li X, Link TM. Does vertebral bone marrow fat content correlate with abdominal adipose tissue, lumbar spine bone mineral density, and blood biomarkers in women with type 2 diabetes mellitus? J Magn Reson Imaging. 2012 Jan; 35(1):117-24. PMID: 22190287.
      View in: PubMed
    61. Haughom B, Schairer W, Souza RB, Carpenter D, Ma CB, Li X. Abnormal tibiofemoral kinematics following ACL reconstruction are associated with early cartilage matrix degeneration measured by MRI T1rho. Knee. 2012 Aug; 19(4):482-7. PMID: 21807522; PMCID: PMC3274608.
    62. Link TM, Li X. Bone marrow changes in osteoarthritis. Semin Musculoskelet Radiol. 2011 Jul; 15(3):238-46. PMID: 21644197.
      View in: PubMed
    63. Masharani UB, Maddux BA, Li X, Sakkas GK, Mulligan K, Schambelan M, Goldfine ID, Youngren JF. Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle. PLoS One. 2011 May 11; 6(5):e19878. PMID: 21589939; PMCID: PMC3092773.
    64. Li X, Kuo D, Schafer AL, Porzig A, Link TM, Black D, Schwartz AV. Quantification of vertebral bone marrow fat content using 3 Tesla MR spectroscopy: reproducibility, vertebral variation, and applications in osteoporosis. J Magn Reson Imaging. 2011 Apr; 33(4):974-9. PMID: 21448966; PMCID: PMC3072841.
    65. Cotofana S, Eckstein F, Wirth W, Souza RB, Li X, Wyman B, Hellio-Le Graverand MP, Link T, Majumdar S. In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging. Eur Radiol. 2011 Jun; 21(6):1127-35. PMID: 21448616; PMCID: PMC3088828.
    66. Tang SY, Souza RB, Ries M, Hansma PK, Alliston T, Li X. Local tissue properties of human osteoarthritic cartilage correlate with magnetic resonance T(1) rho relaxation times. J Orthop Res. 2011 Sep; 29(9):1312-9. PMID: 21445940; PMCID: PMC4092115.
    67. Li X, Kuo D, Theologis A, Carballido-Gamio J, Stehling C, Link TM, Ma CB, Majumdar S. Cartilage in anterior cruciate ligament-reconstructed knees: MR imaging T1{rho} and T2--initial experience with 1-year follow-up. Radiology. 2011 Feb; 258(2):505-14. PMID: 21177392; PMCID: PMC3029884.
    68. Li X, Cheng J, Lin K, Saadat E, Bolbos RI, Jobke B, Ries MD, Horvai A, Link TM, Majumdar S. Quantitative MRI using T1? and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology. Magn Reson Imaging. 2011 Apr; 29(3):324-34. PMID: 21130590; PMCID: PMC3058148.
    69. Theologis AA, Kuo D, Cheng J, Bolbos RI, Carballido-Gamio J, Ma CB, Li X. Evaluation of bone bruises and associated cartilage in anterior cruciate ligament-injured and -reconstructed knees using quantitative t(1?) magnetic resonance imaging: 1-year cohort study. Arthroscopy. 2011 Jan; 27(1):65-76. PMID: 21035995; PMCID: PMC3011041.
    70. Souza RB, Stehling C, Wyman BT, Hellio Le Graverand MP, Li X, Link TM, Majumdar S. The effects of acute loading on T1rho and T2 relaxation times of tibiofemoral articular cartilage. Osteoarthritis Cartilage. 2010 Dec; 18(12):1557-63. PMID: 20950693.
      View in: PubMed
    71. Holtzman DJ, Theologis AA, Carballido-Gamio J, Majumdar S, Li X, Benjamin C. T(1?) and T(2) quantitative magnetic resonance imaging analysis of cartilage regeneration following microfracture and mosaicplasty cartilage resurfacing procedures. J Magn Reson Imaging. 2010 Oct; 32(4):914-23. PMID: 20882622; PMCID: PMC3056553.
    72. Zarins ZA, Bolbos RI, Pialat JB, Link TM, Li X, Souza RB, Majumdar S. Cartilage and meniscus assessment using T1rho and T2 measurements in healthy subjects and patients with osteoarthritis. Osteoarthritis Cartilage. 2010 Nov; 18(11):1408-16. PMID: 20696262; PMCID: PMC2975868.
    73. Luke AC, Stehling C, Stahl R, Li X, Kay T, Takamoto S, Ma B, Majumdar S, Link T. High-field magnetic resonance imaging assessment of articular cartilage before and after marathon running: does long-distance running lead to cartilage damage? Am J Sports Med. 2010 Nov; 38(11):2273-80. PMID: 20631252.
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    74. Rao MN, Mulligan K, Tai V, Wen MJ, Dyachenko A, Weinberg M, Li X, Lang T, Grunfeld C, Schwarz JM, Schambelan M. Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance. J Clin Endocrinol Metab. 2010 Sep; 95(9):4361-6. PMID: 20610601; PMCID: PMC2936071.
    75. Wirth W, Frobell RB, Souza RB, Li X, Wyman BT, Le Graverand MP, Link TM, Majumdar S, Eckstein F. A three-dimensional quantitative method to measure meniscus shape, position, and signal intensity using MR images: a pilot study and preliminary results in knee osteoarthritis. Magn Reson Med. 2010 May; 63(5):1162-71. PMID: 20432287.
      View in: PubMed
    76. Blumenkrantz G, Zuo J, Li X, Kornak J, Link TM, Majumdar S. In vivo 3.0-tesla magnetic resonance T1rho and T2 relaxation mapping in subjects with intervertebral disc degeneration and clinical symptoms. Magn Reson Med. 2010 May; 63(5):1193-200. PMID: 20432290; PMCID: PMC2988488.
    77. Zhao J, Li X, Bolbos RI, Link TM, Majumdar S. Longitudinal assessment of bone marrow edema-like lesions and cartilage degeneration in osteoarthritis using 3 T MR T1rho quantification. Skeletal Radiol. 2010 Jun; 39(6):523-31. PMID: 20195865; PMCID: PMC2929817.
    78. Zuo J, Saadat E, Romero A, Loo K, Li X, Link TM, Kurhanewicz J, Majumdar S. Assessment of intervertebral disc degeneration with magnetic resonance single-voxel spectroscopy. Magn Reson Med. 2009 Nov; 62(5):1140-6. PMID: 19780173; PMCID: PMC4277890.
    79. Li X, Pai A, Blumenkrantz G, Carballido-Gamio J, Link T, Ma B, Ries M, Majumdar S. Spatial distribution and relationship of T1rho and T2 relaxation times in knee cartilage with osteoarthritis. Magn Reson Med. 2009 Jun; 61(6):1310-8. PMID: 19319904; PMCID: PMC2753277.
    80. Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, Mellbovsky L, Peña MJ, Diez-Ferrer O, Mathews P, Randall C, Kuo A, Chen C, Peters M, Kohn D, Buckley J, Li X, Pruitt L, Diez-Perez A, Alliston T, Weaver V, Lotz J. The tissue diagnostic instrument. Rev Sci Instrum. 2009 May; 80(5):054303. PMID: 19485522; PMCID: PMC2832056.
    81. Taylor C, Carballido-Gamio J, Majumdar S, Li X. Comparison of quantitative imaging of cartilage for osteoarthritis: T2, T1rho, dGEMRIC and contrast-enhanced computed tomography. Magn Reson Imaging. 2009 Jul; 27(6):779-84. PMID: 19269769; PMCID: PMC2722506.
    82. Li X, Majumdar S. Section IV: Macromolecular imaging of cartilage. J Bone Joint Surg Am. 2009 Feb; 91 Suppl 1:43. PMID: 19182022; PMCID: PMC2663351.
    83. Lozano J, Saadat E, Li X, Majumdar S, Ma CB. Magnetic resonance T(1 rho) imaging of osteoarthritis: a rabbit ACL transection model. Magn Reson Imaging. 2009 Jun; 27(5):611-6. PMID: 19056196.
      View in: PubMed
    84. Bolbos RI, Ma CB, Link TM, Majumdar S, Li X. In vivo T1rho quantitative assessment of knee cartilage after anterior cruciate ligament injury using 3 Tesla magnetic resonance imaging. Invest Radiol. 2008 Nov; 43(11):782-8. PMID: 18923257; PMCID: PMC2838766.
    85. Rauscher I, Stahl R, Cheng J, Li X, Huber MB, Luke A, Majumdar S, Link TM. Meniscal measurements of T1rho and T2 at MR imaging in healthy subjects and patients with osteoarthritis. Radiology. 2008 Nov; 249(2):591-600. PMID: 18936315; PMCID: PMC2657859.
    86. Zhou ZY, Shan H, Ringgaard S, Zou XN, Zou LJ, Li HS, Li X, Stodkilde-Jorgensen H, Bunger C.Chin J Radiol. Three-dimensional spin-lattice relaxation time in the rotating frame and quantitation of articular cartilage at 7.0 T MR. 2008; 10(42):1101-5.
    87. Stahl R, Luke A, Li X, Carballido-Gamio J, Ma CB, Majumdar S, Link TM. T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients--a 3.0-Tesla MRI study. Eur Radiol. 2009 Jan; 19(1):132-43. PMID: 18709373.
      View in: PubMed
    88. Li X, Ma BC, Bolbos RI, Stahl R, Lozano J, Zuo J, Lin K, Link TM, Safran M, Majumdar S. Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 Tesla. J Magn Reson Imaging. 2008 Aug; 28(2):453-61. PMID: 18666183; PMCID: PMC2666932.
    89. Bolbos RI, Link TM, Ma CB, Majumdar S, Li X. T1rho relaxation time of the meniscus and its relationship with T1rho of adjacent cartilage in knees with acute ACL injuries at 3 T. Osteoarthritis Cartilage. 2009 Jan; 17(1):12-8. PMID: 18602280; PMCID: PMC2838771.
    90. Carballido-Gamio J, Link TM, Li X, Han ET, Krug R, Ries MD, Majumdar S. Feasibility and reproducibility of relaxometry, morphometric, and geometrical measurements of the hip joint with magnetic resonance imaging at 3T. J Magn Reson Imaging. 2008 Jul; 28(1):227-35. PMID: 18581346.
      View in: PubMed
    91. Pai A, Li X, Majumdar S. A comparative study at 3 T of sequence dependence of T2 quantitation in the knee. Magn Reson Imaging. 2008 Nov; 26(9):1215-20. PMID: 18502073; PMCID: PMC2849643.
    92. Saadat E, Jobke B, Chu B, Lu Y, Cheng J, Li X, Ries MD, Majumdar S, Link TM. Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference. Eur Radiol. 2008 Oct; 18(10):2292-302. PMID: 18491096; PMCID: PMC2838768.
    93. Bolbos RI, Zuo J, Banerjee S, Link TM, Ma CB, Li X, Majumdar S. Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI at 3 T. Osteoarthritis Cartilage. 2008 Oct; 16(10):1150-9. PMID: 18387828; PMCID: PMC2580796.
    94. Li X, Han ET, Busse RF, Majumdar S. In vivo T(1rho) mapping in cartilage using 3D magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (3D MAPSS). Magn Reson Med. 2008 Feb; 59(2):298-307. PMID: 18228578; PMCID: PMC2724872.
    95. Zuo J, Bolbos R, Hammond K, Li X, Majumdar S. Reproducibility of the quantitative assessment of cartilage morphology and trabecular bone structure with magnetic resonance imaging at 7 T. Magn Reson Imaging. 2008 May; 26(4):560-6. PMID: 18060717; PMCID: PMC2838765.
    96. Zuo J, Li X, Banerjee S, Han E, Majumdar S. Parallel imaging of knee cartilage at 3 Tesla. J Magn Reson Imaging. 2007 Oct; 26(4):1001-9. PMID: 17896394.
      View in: PubMed
    97. Li X, Youngren JF, Hyun B, Sakkas GK, Mulligan K, Majumdar S, Masharani UB, Schambelan M, Goldfine ID. Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T. Magn Reson Imaging. 2008 Feb; 26(2):188-97. PMID: 17683890; PMCID: PMC2713003.
    98. Stahl R, Blumenkrantz G, Carballido-Gamio J, Zhao S, Munoz T, Hellio Le Graverand-Gastineau MP, Li X, Majumdar S, Link TM. MRI-derived T2 relaxation times and cartilage morphometry of the tibio-femoral joint in subjects with and without osteoarthritis during a 1-year follow-up. Osteoarthritis Cartilage. 2007 Nov; 15(11):1225-34. PMID: 17561417.
      View in: PubMed
    99. Li X, Benjamin Ma C, Link TM, Castillo DD, Blumenkrantz G, Lozano J, Carballido-Gamio J, Ries M, Majumdar S. In vivo T(1rho) and T(2) mapping of articular cartilage in osteoarthritis of the knee using 3 T MRI. Osteoarthritis Cartilage. 2007 Jul; 15(7):789-97. PMID: 17307365; PMCID: PMC2040334.
    100. Majumdar S, Li X, Blumenkrantz G, Saldanha K, Ma CB, Kim H, Lozano J, Link T. MR imaging and early cartilage degeneration and strategies for monitoring regeneration. J Musculoskelet Neuronal Interact. 2006 Oct-Dec; 6(4):382-4. PMID: 17185834.
      View in: PubMed
    101. Blumenkrantz G, Li X, Han ET, Newitt DC, Crane JC, Link TM, Majumdar S. A feasibility study of in vivo T1rho imaging of the intervertebral disc. Magn Reson Imaging. 2006 Oct; 24(8):1001-7. PMID: 16997069.
      View in: PubMed
    102. Lozano J, Li X, Link TM, Safran M, Majumdar S, Ma CB. Detection of posttraumatic cartilage injury using quantitative T1rho magnetic resonance imaging. A report of two cases with arthroscopic findings. J Bone Joint Surg Am. 2006 Jun; 88(6):1349-52. PMID: 16757771.
      View in: PubMed
    103. Li X, Han ET, Ma CB, Link TM, Newitt DC, Majumdar S. In vivo 3T spiral imaging based multi-slice T(1rho) mapping of knee cartilage in osteoarthritis. Magn Reson Med. 2005 Oct; 54(4):929-36. PMID: 16155867.
      View in: PubMed
    104. Li X, Vigneron DB, Cha S, Graves EE, Crawford F, Chang SM, Nelson SJ. Relationship of MR-derived lactate, mobile lipids, and relative blood volume for gliomas in vivo. AJNR Am J Neuroradiol. 2005 Apr; 26(4):760-9. PMID: 15814918.
      View in: PubMed
    105. Pirzkall A, Li X, Oh J, Chang S, Berger MS, Larson DA, Verhey LJ, Dillon WP, Nelson SJ. 3D MRSI for resected high-grade gliomas before RT: tumor extent according to metabolic activity in relation to MRI. Int J Radiat Oncol Biol Phys. 2004 May 01; 59(1):126-37. PMID: 15093908.
      View in: PubMed
    106. Oh J, Henry RG, Pirzkall A, Lu Y, Li X, Catalaa I, Chang S, Dillon WP, Nelson SJ. Survival analysis in patients with glioblastoma multiforme: predictive value of choline-to-N-acetylaspartate index, apparent diffusion coefficient, and relative cerebral blood volume. J Magn Reson Imaging. 2004 May; 19(5):546-54. PMID: 15112303.
      View in: PubMed
    107. Li X, Jin H, Lu Y, Oh J, Chang S, Nelson SJ. Identification of MRI and 1H MRSI parameters that may predict survival for patients with malignant gliomas. NMR Biomed. 2004 Feb; 17(1):10-20. PMID: 15011246.
      View in: PubMed
    108. Nelson SJ, Graves E, Pirzkall A, Li X, Antiniw Chan A, Vigneron DB, McKnight TR. In vivo molecular imaging for planning radiation therapy of gliomas: an application of 1H MRSI. J Magn Reson Imaging. 2002 Oct; 16(4):464-76. PMID: 12353260.
      View in: PubMed
    109. Li X, Lu Y, Pirzkall A, McKnight T, Nelson SJ. Analysis of the spatial characteristics of metabolic abnormalities in newly diagnosed glioma patients. J Magn Reson Imaging. 2002 Sep; 16(3):229-37. PMID: 12205577.
      View in: PubMed
    110. Pirzkall A, Nelson SJ, McKnight TR, Takahashi MM, Li X, Graves EE, Verhey LJ, Wara WW, Larson DA, Sneed PK. Metabolic imaging of low-grade gliomas with three-dimensional magnetic resonance spectroscopy. Int J Radiat Oncol Biol Phys. 2002 Aug 01; 53(5):1254-64. PMID: 12128127.
      View in: PubMed
    111. Li X, Hu G, Gao S. Design and implementation of a novel compression method in a tele-ultrasound system. IEEE Trans Inf Technol Biomed. 1999 Sep; 3(3):205-13. PMID: 10719484.
      View in: PubMed
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