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Artificial Intelligence and Multimodality Data Integration Decipher Tertiary Lymphoid Structure Maturity in Gastric Cancer. Cancer Res. 2025 Dec 15; 85(24):5128-5140.
Wu W, Xun Z, Han Y, Chen Q, Yu S, Luo Y, Hao Z, Chen J, Xu Y, Han X, Qi J, Song K, Ma X, Chen Y, Chen G, Kang M, Jin X, Ding Y, Zhu Z, Hu C, Cheng X, Wang L, Wu P, Liang H, Chen J. PMID: 41150905.
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Developmental-status-aware transcriptional decomposition establishes a cell state panorama of human cancers. Genome Med. 2024 Oct 28; 16(1):124.
Luo Y, Liang H. PMID: 39468667; PMCID: PMC11514945.
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HumansCells
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Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors. Cell. 2024 Sep 05; 187(18):4905-4925.e24.
Luo Y, Xia Y, Liu D, Li X, Li H, Liu J, Zhou D, Dong Y, Li X, Qian Y, Xu C, Tao K, Li G, Pan W, Zhong Q, Liu X, Xu S, Wang Z, Liu R, Zhang W, Shan W, Fang T, Wang S, Peng Z, Jin P, Jin N, Shi S, Chen Y, Wang M, Jiao X, Luo M, Gong W, Wang Y, Yao Y, Zhao Y, Huang X, Ji X, He Z, Zhao G, Liu R, Wu M, Chen G, Hong L, COCPO Consortium, Ma D, Fang Y, Liang H, Gao Q. PMID: 38971151.
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Loss of ADAR1 in macrophages in combination with interferon gamma suppresses tumor growth by remodeling the tumor microenvironment. J Immunother Cancer. 2023 11; 11(11).
Lin W, Luo Y, Wu J, Zhang H, Jin G, Guo C, Zhou H, Liang H, Xu X. PMID: 37935565; PMCID: PMC10649901.
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12 Fields:
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HumansAnimalsCells
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Single-cell dissection of tumor microenvironmental response and resistance to cancer therapy. Trends Genet. 2023 10; 39(10):758-772.
Luo Y, Liang H. PMID: 37658004; PMCID: PMC10529478.
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5 Fields:
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Cxxc finger protein 1 maintains homeostasis and function of intestinal group 3 innate lymphoid cells with aging. Nat Aging. 2023 08; 3(8):965-981.
Shen X, Gao X, Luo Y, Xu Q, Fan Y, Hong S, Huang Z, Liu X, Wang Q, Chen Z, Wang D, Lu L, Wu C, Liang H, Wang L. PMID: 37429951.
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10 Fields:
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AnimalsCells
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Single-Cell Profiling of Tumor Immune Microenvironment Reveals Immune Irresponsiveness in Gastric Signet-Ring Cell Carcinoma. Gastroenterology. 2023 07; 165(1):88-103.
Chen J, Liu K, Luo Y, Kang M, Wang J, Chen G, Qi J, Wu W, Wang B, Han Y, Shi L, Wang K, Han X, Ma X, Liu W, Ding Y, Wang L, Liang H, Wang L, Chen J. PMID: 36921674.
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37 Fields:
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HumansCells
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Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma. Cancer Cell. 2022 11 14; 40(11):1324-1340.e8.
Zhou Z, Chen MM, Luo Y, Mojumdar K, Peng X, Chen H, Kumar SV, Akbani R, Lu Y, Liang H. PMID: 36332624; PMCID: PMC9669221.
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22 Fields:
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HumansAnimalsCells
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RNA editing increases the nucleotide diversity of SARS-CoV-2 in human host cells. PLoS Genet. 2022 03; 18(3):e1010130.
Peng X, Luo Y, Li H, Guo X, Chen H, Ji X, Liang H. PMID: 35353808; PMCID: PMC9000099.
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14 Fields:
Translation:
HumansCellsPHPublic Health
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Convergent Usage of Amino Acids in Human Cancers as A Reversed Process of Tissue Development. Genomics Proteomics Bioinformatics. 2022 02; 20(1):147-162.
Luo Y, Liang H. PMID: 34492340; PMCID: PMC9510935.
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Humans