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Frank Fan

Title(s)Associate Researcher, Anesthesia
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone628-206-8916
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    University of California, San FranciscoPostdoctoral Studies Graduate Division

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Novel Clostridial Neurotoxin Produced by Strain IBCA10-7060 Is Immunologically Equivalent to BoNT/HA. Toxins (Basel). 2019 12 20; 12(1). Fan Y, Barash JR, Conrad F, Lou J, Tam C, Cheng LW, Arnon SS, Marks JD. PMID: 31877649.
      View in: PubMed   Mentions: 2     Fields:    
    2. A three monoclonal antibody combination potently neutralizes multiple botulinum neurotoxin serotype F subtypes. PLoS One. 2017; 12(3):e0174187. Fan Y, Garcia-Rodriguez C, Lou J, Wen W, Conrad F, Zhai W, Smith TJ, Smith LA, Marks JD. PMID: 28323873.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    3. Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. J Infect Dis. 2016 May 15; 213(10):1606-14. Fan Y, Barash JR, Lou J, Conrad F, Marks JD, Arnon SS. PMID: 26936913.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    4. Neutralization of KIT Oncogenic Signaling in Leukemia with Antibodies Targeting KIT Membrane Proximal Domain 5. Mol Cancer Ther. 2015 Nov; 14(11):2595-605. Le Gall M, Crépin R, Neiveyans M, Auclair C, Fan Y, Zhou Y, Marks JD, Pèlegrin A, Poul MA. PMID: 26358753.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B. Toxins (Basel). 2015 Aug 26; 7(9):3405-23. Fan Y, Dong J, Lou J, Wen W, Conrad F, Geren IN, Garcia-Rodriguez C, Smith TJ, Smith LA, Ho M, Pires-Alves M, Wilson BA, Marks JD. PMID: 26343720.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    6. Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity. PLoS One. 2015; 10(8):e0135306. Fan Y, Geren IN, Dong J, Lou J, Wen W, Conrad F, Smith TJ, Smith LA, Ho M, Pires-Alves M, Wilson BA, Marks JD. PMID: 26275214.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    7. Development of an ELISA microarray assay for the sensitive and simultaneous detection of ten biodefense toxins. Analyst. 2014 Oct 21; 139(20):5093-102. Jenko KL, Zhang Y, Kostenko Y, Fan Y, Garcia-Rodriguez C, Lou J, Marks JD, Varnum SM. PMID: 25112421.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    8. Endothelial progenitor cell transplantation improves long-term stroke outcome in mice. Ann Neurol. 2010 Apr; 67(4):488-97. Fan Y, Shen F, Frenzel T, Zhu W, Ye J, Liu J, Chen Y, Su H, Young WL, Yang GY. PMID: 20437584.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    9. A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region. J Mol Biol. 2010 Apr 09; 397(4):1106-18. Dong J, Thompson AA, Fan Y, Lou J, Conrad F, Ho M, Pires-Alves M, Wilson BA, Stevens RC, Marks JD. PMID: 20138889.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    10. Postischemic IGF-1 gene transfer promotes neurovascular regeneration after experimental stroke. J Cereb Blood Flow Metab. 2009 Sep; 29(9):1528-37. Zhu W, Fan Y, Hao Q, Shen F, Hashimoto T, Yang GY, Gasmi M, Bartus RT, Young WL, Chen Y. PMID: 19513085.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    11. Del-1 gene transfer induces cerebral angiogenesis in mice. Brain Res. 2008 Jul 11; 1219:1-7. Fan Y, Zhu W, Yang M, Zhu Y, Shen F, Hao Q, Young WL, Yang GY, Chen Y. PMID: 18534562.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    12. Overexpression of netrin-1 induces neovascularization in the adult mouse brain. J Cereb Blood Flow Metab. 2008 Sep; 28(9):1543-51. Fan Y, Shen F, Chen Y, Hao Q, Liu W, Su H, Young WL, Yang GY. PMID: 18461079.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    13. Insulin growth factor-1 gene transfer enhances neurovascular remodeling and improves long-term stroke outcome in mice. Stroke. 2008 Apr; 39(4):1254-61. Zhu W, Fan Y, Frenzel T, Gasmi M, Bartus RT, Young WL, Yang GY, Chen Y. PMID: 18309153.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    14. Adeno-associated viral vector-mediated hypoxia-regulated VEGF gene transfer promotes angiogenesis following focal cerebral ischemia in mice. Gene Ther. 2008; 15(1):30. Shen F, Fan Y, Su H, Zhu Y, Chen Y, Liu W, Young WL, Yang GY.
    15. Interleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis in vitro. J Cereb Blood Flow Metab. 2008 Jan; 28(1):90-8. Fan Y, Ye J, Shen F, Zhu Y, Yeghiazarians Y, Zhu W, Chen Y, Lawton MT, Young WL, Yang GY. PMID: 17519976.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    16. Therapeutic angiogenesis for brain ischemia: a brief review. J Neuroimmune Pharmacol. 2007 Sep; 2(3):284-9. Fan Y, Yang GY. PMID: 18040863.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    17. Neutrophil depletion decreases VEGF-induced focal angiogenesis in the mature mouse brain. J Cereb Blood Flow Metab. 2007 Nov; 27(11):1853-60. Hao Q, Chen Y, Zhu Y, Fan Y, Palmer D, Su H, Young WL, Yang GY. PMID: 17392691.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    18. MMP-9 expression is associated with leukocytic but not endothelial markers in brain arteriovenous malformations. Front Biosci. 2006 Sep 01; 11:3121-8. Chen Y, Fan Y, Poon KY, Achrol AS, Lawton MT, Zhu Y, McCulloch CE, Hashimoto T, Lee C, Barbaro NM, Bollen AW, Yang GY, Young WL. PMID: 16720380.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    19. Adeno-associated viral-vector-mediated hypoxia-inducible vascular endothelial growth factor gene expression attenuates ischemic brain injury after focal cerebral ischemia in mice. Stroke. 2006 Oct; 37(10):2601-6. Shen F, Su H, Fan Y, Chen Y, Zhu Y, Liu W, Young WL, Yang GY. PMID: 16946160.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    20. Pretreatment with PTD-calbindin D 28k alleviates rat brain injury induced by ischemia and reperfusion. J Cereb Blood Flow Metab. 2007 Apr; 27(4):719-28. Fan Y, Shi L, Gu Y, Zhao Y, Xie J, Qiao J, Yang GY, Wang Y, Lu CZ. PMID: 16868556.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    21. Interleukin-6 upregulates expression of KDR and stimulates proliferation of human cerebrovascular smooth muscle cells. J Cereb Blood Flow Metab. 2007 Mar; 27(3):510-20. Yao JS, Zhai W, Fan Y, Lawton MT, Barbaro NM, Young WL, Yang GY. PMID: 16820800.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    22. In vivo delivery of a XIAP (BIR3-RING) fusion protein containing the protein transduction domain protects against neuronal death induced by seizures. Exp Neurol. 2006 Feb; 197(2):301-8. Li T, Fan Y, Luo Y, Xiao B, Lu C. PMID: 16336964.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP). Neurochem Int. 2006 Jan; 48(1):50-9. Fan YF, Lu CZ, Xie J, Zhao YX, Yang GY. PMID: 16293346.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    24. The mutation in exon 8 of CCMI gene and 704 insT in patients with intracranialcavernoushemangioma [Chinese]. Fudan University J. of Medical science. 2005, 3. 2005. Xie R, Chen XC, Fan Y, Ren HM, Gao L, Xia Y and Li XM.
    25. Analysis of CCM1 gene mutations in Chinese patients with intracranial cavernous malformations [Chinese]. Zhonghua Yi Xue Za Zhi. 2005, 85(32): 2254. 2005; 85(32):2254. Xie R, Chen XC, Fan Y, Xia Y, Gao L, Li XM.
    26. A case report for a new samesense mutation of 17th exon of CCM1 gene [Chinese]. Chin J Clin Neurosci. 2004; 12(4):293. Xie R, Chen XC, Fan Y, Ren HM, Xia Y, Ji YD and Li XM.
    27. Signal pathway in neuromuscular junction and myasthenia gravis [Chinese]. Chinese J. Neurology. 2004; 37(5):465. Fan Y, Lu CZ and Ren HM.
    28. New mutations of the 12th exon of CCM1 gene in Chinese patients with intracranial cavernous angiomas [Chinese]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004; 21(3):264. Xie R, Chen XC, Fan Y, Ren HM, Xia Y, Ji YD, Hu J.
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