Young-Wook Jun, PhD

Title(s)Professor, Otolaryngology
SchoolSchool of Medicine
Address1450 Third St, #365
San Francisco CA 94158
ORCID ORCID Icon0000-0003-3182-5366 Additional info
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    Young-wook Jun attended Yonsei University in Korea, where he received a Bachelor's degree in Chemistry in 1999. He did his graduate studies at the Korea Advances Institute of Science, where he broadly investigated the chemistry of nanocrystals. He carried out postdoctoral studies with Prof. Paul Alivisatos at the University of California, Berkeley when he first began research related to microscopy- and nanotechnology-based biophysical tools. In 2010, he joined the faculty of UCSF, where he is presently a professor. He received the Endowed Hemming Fellowship, Sandler-UCSF New Frontier Research Award, The World Most-Influential Scientific Mind.
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    Notch1 and APP signaling in cerebral microvascular dysfunction
    NIH R21AG072232Apr 15, 2021 - Mar 31, 2023
    Role: Co-Principal Investigator
    Spatiotemporal interrogation of molecular mechanobiololgy at the cell-cell interface with nanotechnology tools
    NIH R35GM134948Mar 1, 2020 - Feb 28, 2025
    Role: Principal Investigator
    In situ Investigation of dynamic protein-protein interactions in live cells via Magnetic Co-concentration (MCoC)
    NIH R21CA224364Jan 1, 2018 - Dec 31, 2019
    Role: Principal Investigator
    Nanomodules for interrogating chemical, spatial, and mechanical dynamics of cell surface receptors
    NIH R01GM126542Sep 15, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Interrogation of mechanotransduction ion channels via nanoruler force microscopy and mechanogenetic nanomodules
    NIH 1R21NS103240-01Jul 1, 2017 - Jun 30, 2019
    Role: Principal Investigator
    Spatial Mutation of Membrane Protein Assembly Dynamics Using Nano-Actuators
    NIH R21HL123329Sep 1, 2014 - Jun 30, 2017
    Role: Principal Investigator
    Spatiotemporal Control of Dynamic Notch Signaling with Subcellular Resolution
    NIH R01GM112081Aug 1, 2014 - Jul 31, 2019
    Role: Principal Investigator
    Small, modular, and monovalent Quantum Dots for single molecule imaging of Notch
    NIH R21EB018044Mar 1, 2014 - Feb 29, 2016
    Role: Principal Investigator
    Single Molecule Imaging of Guided Axonal Development using Plasmon Nanorulers
    NIH R21EB015088Mar 15, 2012 - Feb 28, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yeast lunapark regulates the formation of trans-Sey1p complexes for homotypic ER membrane fusion. iScience. 2023 Dec 15; 26(12):108386. Jang E, Lee M, Yoon SY, Lee SS, Park J, Jin MS, Eom SH, Lee C, Jun Y. PMID: 38025788; PMCID: PMC10679814.
      View in: PubMed   Mentions:
    2. Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion. J Cell Biol. 2023 12 04; 222(12). White MJ, Jacobs KA, Singh T, Mayo LN, Lin A, Chen CS, Jun YW, Kutys ML. PMID: 37796194; PMCID: PMC10555887.
      View in: PubMed   Mentions:    Fields:    
    3. Hydrogel Magnetomechanical Actuator Nanoparticles for Wireless Remote Control of Mechanosignaling In Vivo. Nano Lett. 2023 06 14; 23(11):5227-5235. Jeong S, Shin W, Park M, Lee JU, Lim Y, Noh K, Lee JH, Jun YW, Kwak M, Cheon J. PMID: 37192537; PMCID: PMC10614426.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    4. Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling. Nat Cell Biol. 2022 12; 24(12):1739-1753. Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, Kutys ML, Seo D, Kim HH, Kim YH, Cheon J, Gartner ZJ, Jun YW. PMID: 36456828; PMCID: PMC10665132.
      View in: PubMed   Mentions: 5     Fields:    
    5. Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen. ACS Appl Mater Interfaces. 2021 Nov 24; 13(46):54739-54752. Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR. PMID: 34752058.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    6. Small, Clickable, and Monovalent Magnetofluorescent Nanoparticles Enable Mechanogenetic Regulation of Receptors in a Crowded Live-Cell Microenvironment. Nano Lett. 2019 06 12; 19(6):3761-3769. Kwak M, Gu W, Jeong H, Lee H, Lee JU, An M, Kim YH, Lee JH, Cheon J, Jun YW. PMID: 31037941; PMCID: PMC6615472.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    7. Magnetic Nanotweezers for Interrogating Biological Processes in Space and Time. Acc Chem Res. 2018 04 17; 51(4):839-849. Kim JW, Jeong HK, Southard KM, Jun YW, Cheon J. PMID: 29589897; PMCID: PMC5917604.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    8. Single-cell mechanogenetics using monovalent magnetoplasmonic nanoparticles. Nat Protoc. 2017 Sep; 12(9):1871-1889. Kim JW, Seo D, Lee JU, Southard KM, Lim Y, Kim D, Gartner ZJ, Jun YW, Cheon J. PMID: 28817122; PMCID: PMC5742362.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    9. A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time. Cell. 2016 Jun 02; 165(6):1507-1518. Seo D, Southard KM, Kim JW, Lee HJ, Farlow J, Lee JU, Litt DB, Haas T, Alivisatos AP, Cheon J, Gartner ZJ, Jun YW. PMID: 27180907; PMCID: PMC4892966.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    10. Monovalent plasmonic nanoparticles for biological applications. Proceedings of SPIE--the International Society for Optical Engineering. 2016; 9722:972201. Daeha Seo, Hyunjung Lee, Jung-uk Lee, Thomas Haas, Young-wook Jun. . View Publication.
    11. In Vitro Capture of Small Ferrous Particles with a Magnetic Filtration Device Designed for Intravascular Use with Intraarterial Chemotherapy: Proof-of-Concept Study. J Vasc Interv Radiol. 2016 Mar; 27(3):426-32.e1. Mabray MC, Lillaney P, Sze CH, Losey AD, Yang J, Kondapavulur S, Liu D, Saeed M, Patel A, Cooke D, Jun YW, El-Sayed I, Wilson M, Hetts SW. PMID: 26706187; PMCID: PMC4769113.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    12. SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiae. J Cell Biol. 2015 Aug 03; 210(3):451-70. Lee M, Ko YJ, Moon Y, Han M, Kim HW, Lee SH, Kang K, Jun Y. PMID: 26216899; PMCID: PMC4523606.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    13. Production and targeting of monovalent quantum dots. J Vis Exp. 2014 Oct 23; (92):e52198. Seo D, Farlow J, Southard K, Jun YW, Gartner ZJ. PMID: 25407345; PMCID: PMC4309134.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Sensitive and selective plasmon ruler nanosensors for monitoring the apoptotic drug response in leukemia. ACS Nano. 2014 Sep 23; 8(9):9199-208. Tajon CA, Seo D, Asmussen J, Shah N, Jun YW, Craik CS. PMID: 25166742; PMCID: PMC4174091.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    15. Single-molecule sensing of caspase activation in live cells via plasmon coupling nanotechnology. Methods Enzymol. 2014; 544:271-97. Tajon C, Jun YW, Craik CS. PMID: 24974294.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    16. MEK-dependent negative feedback underlies BCR-ABL-mediated oncogene addiction. Cancer Discov. 2014 Feb; 4(2):200-15. Asmussen J, Lasater EA, Tajon C, Oses-Prieto J, Jun YW, Taylor BS, Burlingame A, Craik CS, Shah NP. PMID: 24362263; PMCID: PMC4248023.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    17. Formation of targeted monovalent quantum dots by steric exclusion. Nat Methods. 2013 Dec; 10(12):1203-5. Farlow J, Seo D, Broaders KE, Taylor MJ, Gartner ZJ, Jun YW. PMID: 24122039; PMCID: PMC3968776.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    18. Biotite dissolution in brine at varied temperatures and CO2 pressures: its activation energy and potential CO2 intercalation. Langmuir. 2012 Oct 16; 28(41):14633-41. Hu Y, Jun YS. PMID: 22989382.
      View in: PubMed   Mentions: 2     Fields:    
    19. Coupling of optical resonances in a compositionally asymmetric plasmonic nanoparticle dimer. Nano Lett. 2010 Jul 14; 10(7):2655-60. Sheikholeslami S, Jun YW, Jain PK, Alivisatos AP. PMID: 20536212.
      View in: PubMed   Mentions: 30     Fields:    
    20. Hetero-epitaxial anion exchange yields single-crystalline hollow nanoparticles. J Am Chem Soc. 2009 Oct 07; 131(39):13943-5. Park J, Zheng H, Jun YW, Alivisatos AP. PMID: 19788329.
      View in: PubMed   Mentions: 17     Fields:    
    21. Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation at the single-molecule level. Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42):17735-40. Jun YW, Sheikholeslami S, Hostetter DR, Tajon C, Craik CS, Alivisatos AP. PMID: 19805121; PMCID: PMC2764940.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    22. Observation of single colloidal platinum nanocrystal growth trajectories. Science. 2009 Jun 05; 324(5932):1309-12. Zheng H, Smith RK, Jun YW, Kisielowski C, Dahmen U, Alivisatos AP. PMID: 19498166.
      View in: PubMed   Mentions: 121     Fields:    
    23. Nanoscaling laws of magnetic nanoparticles and their applicabilities in biomedical sciences. Acc Chem Res. 2008 Feb; 41(2):179-89. Jun YW, Seo JW, Cheon J. PMID: 18281944.
      View in: PubMed   Mentions: 104     Fields:    Translation:Animals
    24. Chemical design of nanoparticle probes for high-performance magnetic resonance imaging. Angew Chem Int Ed Engl. 2008; 47(28):5122-35. Jun YW, Lee JH, Cheon J. PMID: 18574805.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimals
    25. Highly crystalline anisotropic superstructures via magnetic field induced nanoparticle assembly. Chem Commun (Camb). 2007 Dec 21; (47):5001-3. Park JI, Jun YW, Choi JS, Cheon J. PMID: 18049733.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    26. Hybrid Nanoparticles for Magnetic Resonance Imaging of Target-Specific Viral Gene Delivery. Advanced Materials. 2007; 19(20):3109-12. Yong-Min Huh, Eun-Sook Lee, Jae-Hyun Lee, Young-wook Jun, Pyung-Hwan Kim, Chae-Ok Yun, Joo-Hang Kim, Jin-Suck Suh, Jinwoo Cheon. View Publication.
    27. Two-dimensional nanosheet crystals. Angew Chem Int Ed Engl. 2007; 46(46):8828-31. Seo JW, Jun YW, Park SW, Nah H, Moon T, Park B, Kim JG, Kim YJ, Cheon J. PMID: 17939146.
      View in: PubMed   Mentions: 18     Fields:    
    28. Magnetic nanoparticle assisted molecular MR imaging. Adv Exp Med Biol. 2007; 620:85-106. Jun YW, Jang JT, Cheon J. PMID: 18217337.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    29. Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging. Nat Med. 2007 Jan; 13(1):95-9. Lee JH, Huh YM, Jun YW, Seo JW, Jang JT, Song HT, Kim S, Cho EJ, Yoon HG, Suh JS, Cheon J. PMID: 17187073.
      View in: PubMed   Mentions: 376     Fields:    Translation:HumansAnimalsCells
    30. Biocompatible heterostructured nanoparticles for multimodal biological detection. J Am Chem Soc. 2006 Dec 20; 128(50):15982-3. Choi JS, Jun YW, Yeon SI, Kim HC, Shin JS, Cheon J. PMID: 17165720.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    31. Heterostructured magnetic nanoparticles: their versatility and high performance capabilities. Chem Commun (Camb). 2007 Mar 28; (12):1203-14. Jun YW, Choi JS, Cheon J. PMID: 17356759.
      View in: PubMed   Mentions: 16     Fields:    
    32. Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma. Angew Chem Int Ed Engl. 2006 Dec 11; 45(48):8160-2. Lee JH, Jun YW, Yeon SI, Shin JS, Cheon J. PMID: 17103471.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    33. Shape control of semiconductor and metal oxide nanocrystals through nonhydrolytic colloidal routes. Angew Chem Int Ed Engl. 2006 May 19; 45(21):3414-39. Jun YW, Choi JS, Cheon J. PMID: 16642516.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    34. Magnetic superlattices and their nanoscale phase transition effects. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3023-7. Cheon J, Park JI, Choi JS, Jun YW, Kim S, Kim MG, Kim YM, Kim YJ. PMID: 16492783; PMCID: PMC1413888.
      View in: PubMed   Mentions: 7     Fields:    
    35. Selective catalytic activity of ball-shaped Pd@MCM-48 nanocatalysts. Chem Commun (Camb). 2006 Mar 28; (12):1325-7. Lee HY, Ryu S, Kang H, Jun YW, Cheon J. PMID: 16538262.
      View in: PubMed   Mentions: 1     Fields:    
    36. The concept of delayed nucleation in nanocrystal growth demonstrated for the case of iron oxide nanodisks. J Am Chem Soc. 2006 Feb 08; 128(5):1675-82. Casula MF, Jun YW, Zaziski DJ, Chan EM, Corrias A, Alivisatos AP. PMID: 16448141.
      View in: PubMed   Mentions: 13     Fields:    
    37. In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals. J Am Chem Soc. 2005 Sep 07; 127(35):12387-91. Huh YM, Jun YW, Song HT, Kim S, Choi JS, Lee JH, Yoon S, Kim KS, Shin JS, Suh JS, Cheon J. PMID: 16131220.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    38. Symmetry-controlled colloidal nanocrystals: nonhydrolytic chemical synthesis and shape determining parameters. J Phys Chem B. 2005 Aug 11; 109(31):14795-806. Jun YW, Lee JH, Choi JS, Cheon J. PMID: 16852873.
      View in: PubMed   Mentions: 2     Fields:    
    39. Surface modulation of magnetic nanocrystals in the development of highly efficient magnetic resonance probes for intracellular labeling. J Am Chem Soc. 2005 Jul 20; 127(28):9992-3. Song HT, Choi JS, Huh YM, Kim S, Jun YW, Suh JS, Cheon J. PMID: 16011350.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    40. Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging. J Am Chem Soc. 2005 Apr 27; 127(16):5732-3. Jun YW, Huh YM, Choi JS, Lee JH, Song HT, Kim S, Yoon S, Kim KS, Shin JS, Suh JS, Cheon J. PMID: 15839639.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansAnimalsCells
    41. In situ one-pot synthesis of 1-dimensional transition metal oxide nanocrystals. J Phys Chem B. 2005 Mar 31; 109(12):5389-91. Seo JW, Jun YW, Ko SJ, Cheon J. PMID: 16851566.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    42. Recent advances in the shape control of inorganic nano-building blocks. Coordination Chemistry Reviews. 2005; 249(17-18):1766-75. Young-wook Jun, Jung-wook Seo, Sang Jun Oh, Jinwoo Cheon. View Publication.
    43. Spontaneous one dimensional arrangement of spherical Au nanoparticles with liquid crystal ligands. Chem Commun (Camb). 2005 Feb 14; (6):800-1. In I, Jun YW, Kim YJ, Kim SY. PMID: 15685343.
      View in: PubMed   Mentions: 3     Fields:    
    44. Thiacrownether-mediated Size-controlled Assembly of Gold Nanoparticles. Chemistry Letters. 2004; 33(11):1530-1. Insik In, Young-Wook Jun, Yun Jun Kim, Sang Youl Kim. View Publication.
    45. Characterization of superparamagnetic "core-shell" nanoparticles and monitoring their anisotropic phase transition to ferromagnetic "solid solution" nanoalloys. J Am Chem Soc. 2004 Jul 28; 126(29):9072-8. Park JI, Kim MG, Jun YW, Lee JS, Lee WR, Cheon J. PMID: 15264840.
      View in: PubMed   Mentions: 3     Fields:    
    46. Surfactant-assisted elimination of a high energy facet as a means of controlling the shapes of TiO2 nanocrystals. J Am Chem Soc. 2003 Dec 24; 125(51):15981-5. Jun YW, Casula MF, Sim JH, Kim SY, Cheon J, Alivisatos AP. PMID: 14677990.
      View in: PubMed   Mentions: 19     Fields:    
    47. Sterically induced shape and crystalline phase control of GaP nanocrystals. J Am Chem Soc. 2002 Nov 20; 124(46):13656-7. Kim YH, Jun YW, Jun BH, Lee SM, Cheon J. PMID: 12431078.
      View in: PubMed   Mentions: 3     Fields:    
    48. Single-crystalline star-shaped nanocrystals and their evolution: programming the geometry of nano-building blocks. J Am Chem Soc. 2002 Sep 25; 124(38):11244-5. Lee SM, Jun YW, Cho SN, Cheon J. PMID: 12236719.
      View in: PubMed   Mentions: 13     Fields:    
    49. Superlattice and magnetism directed by the size and shape of nanocrystals. Chemphyschem. 2002 Jun 17; 3(6):543-7. Park JI, Kang NJ, Jun YW, Oh SJ, Ri HC, Cheon J. PMID: 12465496.
      View in: PubMed   Mentions: 8     Fields:    
    50. Architectural control of magnetic semiconductor nanocrystals. J Am Chem Soc. 2002 Jan 30; 124(4):615-9. Jun YW, Jung YY, Cheon J. PMID: 11804492.
      View in: PubMed   Mentions: 3     Fields:    
    51. Controlled synthesis of multi-armed CdS nanorod architectures using monosurfactant system. J Am Chem Soc. 2001 May 30; 123(21):5150-1. Jun YW, Lee SM, Kang NJ, Cheon J. PMID: 11457367.
      View in: PubMed   Mentions: 9     Fields:    
    52. Size and shape controlled ZnTe nanocrystals with quantum confinement effect. Chemical Communications. 2000; 2001:101-2. Young-wook Jun, Chang-Shik Choi, Jinwoo Cheon. View Publication.
    53. Synthesis of Porous Palladium Superlattice Nanoballs and Nanowires. Chemistry of Materials. 2000; 12(12):3530-2. Hongkyu Kang, Young-wook Jun, Jong-Il Park, Kyung-Bok Lee, and Jinwoo Cheon. View Publication.
    54. One-step synthesis of size tuned zinc selenide quantum dots via a temperature controlled molecular precursor approach. Chemical Communications. 2000; 2000:1243-4. Young-wook Jun, Ja-Eung Koo, Jinwoo Cheon. View Publication.
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