Zachary Hill, PhD

TitleAssociate Specialist
InstitutionUniversity of California San Francisco
DepartmentPharmaceutical Chemistry
AddressLocation Required
Varies CA 00000
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    Collapse Research 
    Collapse Research Activities and Funding
    Mapping the conformation-specific interactome of signaling proteins
    NIH/NCI K99CA203002Apr 1, 2016 - Mar 31, 2018
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Keedy DA, Hill Z, Biel JT, Kang E, Rettenmaier TJ, Brandao-Neto J, Pearce NM, von Delft F, Wells JA, Fraser JS. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife. 2018 Jun 07; 7. PMID: 29877794.
      View in: PubMed
    2. Hill Z, Martinko AJ, Nguyen DP, Wells JA. Human antibody-based chemically induced dimerizers for cell therapeutic applications. Nat Chem Biol. 2018 Feb; 14(2):112-117. PMID: 29200207.
      View in: PubMed
    3. Rog D, Grigsby P, Hill Z, Pinette W, Inceoglu S, Zuckerman L. A biomechanical comparison of the two- and four-hole side-plate dynamic hip screw in an osteoporotic composite femur model. J Orthop Surg (Hong Kong). 2017 May-Aug; 25(2):2309499017717199. PMID: 28664768.
      View in: PubMed
    4. Hill Z, Pollock SB, Zhuang M, Wells JA. Direct Proximity Tagging of Small Molecule Protein Targets Using an Engineered NEDD8 Ligase. J Am Chem Soc. 2016 10 12; 138(40):13123-13126. PMID: 27626304.
      View in: PubMed
    5. Li Q, Hill Z, He BJ. Spatiotemporal dissociation of brain activity underlying subjective awareness, objective performance and confidence. J Neurosci. 2014 Mar 19; 34(12):4382-95. PMID: 24647958; PMCID: PMC3960476.
    6. Andrews SS, Hill Z, Perera BG, Maly DJ. Label transfer reagents to probe p38 MAPK binding partners. Chembiochem. 2013 Jan 21; 14(2):209-16. PMID: 23319368; PMCID: PMC3762675.
    7. Hill Z, Perera BG, Andrews SS, Maly DJ. Targeting diverse signaling interaction sites allows the rapid generation of bivalent kinase inhibitors. ACS Chem Biol. 2012 Mar 16; 7(3):487-95. PMID: 22148755; PMCID: PMC3306478.
    8. Gregersen KA, Hill Z, Gadd JC, Fujimoto BS, Maly DJ, Chiu DT. Intracellular delivery of bioactive molecules using light-addressable nanocapsules. ACS Nano. 2010 Dec 28; 4(12):7603-11. PMID: 21117640; PMCID: PMC3075813.
    9. Hill Z, Perera BG, Maly DJ. Bivalent inhibitors of the tyrosine kinases ABL and SRC: determinants of potency and selectivity. Mol Biosyst. 2011 Feb; 7(2):447-56. PMID: 21060940; PMCID: PMC3268058.
    10. Hill Z, Perera BG, Maly DJ. A chemical genetic method for generating bivalent inhibitors of protein kinases. J Am Chem Soc. 2009 May 20; 131(19):6686-8. PMID: 19391594.
      View in: PubMed
    11. Hill Z, Rodovsky DB, Leger JM, Bartholomew GP. Synthesis and utilization of perylene-based n-type small molecules in light-emitting electrochemical cells. Chem Commun (Camb). 2008 Dec 28; (48):6594-6. PMID: 19057790.
      View in: PubMed
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