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Zachary Hill, PhD

TitleASSOC SPECIALIST
InstitutionUniversity of California San Francisco
DepartmentPharmaceutical Chemistry
AddressLocation Required
Varies CA 00000
Phone415-514-4757
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    Collapse Research 
    Collapse Research Activities and Funding
    Mapping the conformation-specific interactome of signaling proteins
    NIH/NCI K99CA203002Apr 1, 2016 - Mar 31, 2018
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Henderson AR, Henley MJ, Foster NJ, Peiffer AL, Beyersdorf MS, Stanford KD, Sturlis SM, Linhares BM, Hill ZB, Wells JA, Cierpicki T, Brooks CL, Fierke CA, Mapp AK. Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators. Proc Natl Acad Sci U S A. 2018 Aug 20. PMID: 30127017.
      View in: PubMed
    2. Keedy DA, Hill ZB, Biel JT, Kang E, Rettenmaier TJ, Brandao-Neto J, Pearce NM, von Delft F, Wells JA, Fraser JS. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife. 2018 Jun 07; 7. PMID: 29877794.
      View in: PubMed
    3. Hill ZB, Martinko AJ, Nguyen DP, Wells JA. Human antibody-based chemically induced dimerizers for cell therapeutic applications. Nat Chem Biol. 2018 Feb; 14(2):112-117. PMID: 29200207.
      View in: PubMed
    4. Rog D, Grigsby P, Hill Z, Pinette W, Inceoglu S, Zuckerman L. A biomechanical comparison of the two- and four-hole side-plate dynamic hip screw in an osteoporotic composite femur model. J Orthop Surg (Hong Kong). 2017 May-Aug; 25(2):2309499017717199. PMID: 28664768.
      View in: PubMed
    5. Hill ZB, Pollock SB, Zhuang M, Wells JA. Direct Proximity Tagging of Small Molecule Protein Targets Using an Engineered NEDD8 Ligase. J Am Chem Soc. 2016 10 12; 138(40):13123-13126. PMID: 27626304.
      View in: PubMed
    6. Li Q, Hill Z, He BJ. Spatiotemporal dissociation of brain activity underlying subjective awareness, objective performance and confidence. J Neurosci. 2014 Mar 19; 34(12):4382-95. PMID: 24647958; PMCID: PMC3960476.
    7. Andrews SS, Hill ZB, Perera BG, Maly DJ. Label transfer reagents to probe p38 MAPK binding partners. Chembiochem. 2013 Jan 21; 14(2):209-16. PMID: 23319368; PMCID: PMC3762675.
    8. Hill ZB, Perera BG, Andrews SS, Maly DJ. Targeting diverse signaling interaction sites allows the rapid generation of bivalent kinase inhibitors. ACS Chem Biol. 2012 Mar 16; 7(3):487-95. PMID: 22148755; PMCID: PMC3306478.
    9. Gregersen KA, Hill ZB, Gadd JC, Fujimoto BS, Maly DJ, Chiu DT. Intracellular delivery of bioactive molecules using light-addressable nanocapsules. ACS Nano. 2010 Dec 28; 4(12):7603-11. PMID: 21117640; PMCID: PMC3075813.
    10. Hill ZB, Perera BG, Maly DJ. Bivalent inhibitors of the tyrosine kinases ABL and SRC: determinants of potency and selectivity. Mol Biosyst. 2011 Feb; 7(2):447-56. PMID: 21060940; PMCID: PMC3268058.
    11. Hill ZB, Perera BG, Maly DJ. A chemical genetic method for generating bivalent inhibitors of protein kinases. J Am Chem Soc. 2009 May 20; 131(19):6686-8. PMID: 19391594.
      View in: PubMed
    12. Hill ZB, Rodovsky DB, Leger JM, Bartholomew GP. Synthesis and utilization of perylene-based n-type small molecules in light-emitting electrochemical cells. Chem Commun (Camb). 2008 Dec 28; (48):6594-6. PMID: 19057790.
      View in: PubMed
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