Zachary Matthay, MD

Title(s)Resident, Surgery
SchoolSchool of Medicine
Address35 Medical Center Way
San Francisco CA 94143
Phone415-476-1239
ORCID ORCID Icon0000-0002-3062-2535 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Tufts University, Medford, MABS05/2011Biology
    UCSF, San Francisco, CAMD5/2016Medicine
    Collapse Awards and Honors
    American College of Surgeons2021Basic Science Award 2nd Place, Committee on Trauma Resident Paper National Competition
    American College of Surgeons2019Basic Science Award 2nd Place, Committee on Trauma Resident Paper Regional Competition
    Western Trauma Association2020Ernest Moore Resident Prize for Basic Science
    UCSF2017Krevans Award for Excellence in Patient Care

    Collapse Overview 
    Collapse Overview
    Zachary Matthay, M.D. is a general surgery resident at UCSF. He received his Bachelor's of Science in Biology from Tufts University and received his M.D. from the University of California, San Francisco in 2016. His research interests include platelet and coagulation biology, thromboembolism, and clinical outcomes research. During his research years, he studied the role of platelets in trauma induced coagulopathy in Dr. Lucy Kornblith's laboratory, and under the mentorship of Dr. James Iannuzzi he performed clinical outcomes research in vascular surgery including projects examining risk factors for post-operative major adverse cardiovascular events and venous thromboembolism. Dr. Matthay’s primary clinical interest is in vascular surgery after completing is general surgery residency.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Racial and ethnic disparities in major adverse limb events persist for chronic limb threatening ischemia despite presenting limb threat severity after peripheral vascular intervention. J Vasc Surg. 2022 Nov 02. Jaramillo EA, Smith EJT, Matthay ZA, Sanders KM, Hiramoto JS, Gasper WJ, Conte MS, Iannuzzi JC. PMID: 36334848.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. "Importance of catecholamine signaling in the development of platelet exhaustion after traumatic injury": Reply. J Thromb Haemost. 2022 11; 20(11):2717-2718. Matthay ZA, Fields AT, Kornblith LZ. PMID: 36271462.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. COVID-19-associated Lung Microvascular Endotheliopathy: A "From the Bench" Perspective. Am J Respir Crit Care Med. 2022 10 15; 206(8):961-972. Joffre J, Rodriguez L, Matthay ZA, Lloyd E, Fields AT, Bainton RJ, Kurien P, Sil A, Calfee CS, Woodruff PG, Erle DJ, Hendrickson C, Krummel MF, Langelier CR, Matthay MA, Kornblith LZ, Hellman J, COVID-19 Multi-Phenotyping for Effective Therapies (COMET) Consortium, COVID-19 Associated Coagulopathy, Inflammation, and Thrombosis (Co-ACIT) Study Group. PMID: 35649173; PMCID: PMC9801996.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    4. Association of Intraoperative and Perioperative Transfusions with Postoperative Cardiovascular Events and Mortality After Infrainguinal Revascularization. Ann Vasc Surg. 2023 Jan; 88:70-78. Matthay ZA, Smith EJ, Flanagan CP, Wu B, Malas MB, Hiramoto JS, Conte MS, Iannuzzi JC. PMID: 35872210.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Clinical Predictors and Outcomes Associated with Postoperative Delirium Following Infrainguinal Bypass Surgery. Ann Vasc Surg. 2022 Nov; 87:254-262. Gutierrez RD, Matthay ZA, Smith EJT, Linderman K, Gasper WJ, Hiramoto JS, Conte MS, Iannuzzi JC. PMID: 35803458.
      View in: PubMed   Mentions:    Fields:    
    6. Importance of catecholamine signaling in the development of platelet exhaustion after traumatic injury. J Thromb Haemost. 2022 09; 20(9):2109-2118. Matthay ZA, Fields AT, Nunez-Garcia B, Park JJ, Jones C, Leligdowicz A, Hendrickson CM, Callcut RA, Matthay MA, Kornblith LZ. PMID: 35592998.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Postinjury platelet aggregation and venous thromboembolism. J Trauma Acute Care Surg. 2022 11 01; 93(5):604-612. Matthay ZA, Hellmann ZJ, Nunez-Garcia B, Fields AT, Cuschieri J, Neal MD, Berger JS, Luttrell-Williams E, Knudson MM, Cohen MJ, Callcut RA, Kornblith LZ. PMID: 35444156; PMCID: PMC9585095.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. A new trauma frontier: Exploratory pilot study of platelet transcriptomics in trauma patients. J Trauma Acute Care Surg. 2022 02 01; 92(2):313-322. Fields AT, Lee MC, Mayer F, Santos YA, Bainton CMV, Matthay ZA, Callcut RA, Mayer N, Cuschieri J, Kober KM, Bainton RJ, Kornblith LZ. PMID: 34738997; PMCID: PMC8781218.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. A Parallel Pandemic: Increased Firearm Injuries at Five Northern California Trauma Centers During the COVID-19 Pandemic: An Interrupted Time-series Analysis. Ann Surg. 2022 05 01; 275(5):e725-e727. Matthay ZA, Callcut RA, Kwok AM, Aarabi S, Forrester JD, Kornblith LZ, Northern California Research Consortium for Trauma & Acute Care Sur. PMID: 34913894; PMCID: PMC9083313.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    10. Enhanced recovery after surgery protocol and postoperative opioid prescribing for cesarean delivery: an interrupted time series analysis. Perioper Med (Lond). 2021 Nov 15; 10(1):38. Langnas EM, Matthay ZA, Lin A, Harbell MW, Croci R, Rodriguez-Monguio R, Chen CL. PMID: 34775985; PMCID: PMC8591895.
      View in: PubMed   Mentions: 1  
    11. Inequity in discharge pain management for trauma patients with limited English proficiency. J Trauma Acute Care Surg. 2021 11 01; 91(5):898-902. Schwartz HEM, Matthay ZA, Menza R, Fern?ndez A, Mackersie R, Stein DM, Bongiovanni T. PMID: 34039923.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Risk factors for venous thromboembolism after vascular surgery and implications for chemoprophylaxis strategies. J Vasc Surg Venous Lymphat Disord. 2022 05; 10(3):585-593.e2. Matthay ZA, Flanagan CP, Sanders K, Smith EJ, Lancaster EM, Gasper WJ, Kornblith LZ, Hiramoto JS, Conte MS, Iannuzzi JC. PMID: 34637952; PMCID: PMC9056001.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Outcomes after ultramassive transfusion in the modern era: An Eastern Association for the Surgery of Trauma multicenter study. J Trauma Acute Care Surg. 2021 07 01; 91(1):24-33. Matthay ZA, Hellmann ZJ, Callcut RA, Matthay EC, Nunez-Garcia B, Duong W, Nahmias J, LaRiccia AK, Spalding MC, Dalavayi SS, Reynolds JK, Lesch H, Wong YM, Chipman AM, Kozar RA, Penaloza L, Mukherjee K, Taghlabi K, Guidry CA, Seng SS, Ratnasekera A, Motameni A, Udekwu P, Madden K, Moore SA, Kirsch J, Goddard J, Haan J, Lightwine K, Ontengco JB, Cullinane DC, Spitzer SA, Kubasiak JC, Gish J, Hazelton JP, Byskosh AZ, Posluszny JA, Ross EE, Park JJ, Robinson B, Abel MK, Fields AT, Esensten JH, Nambiar A, Moore J, Hardman C, Terse P, Luo-Owen X, Stiles A, Pearce B, Tann K, Abdul Jawad K, Ruiz G, Kornblith LZ. PMID: 34144557; PMCID: PMC8243874.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. The DISTANCE study: Determining the impact of social distancing on trauma epidemiology during the COVID-19 epidemic-An interrupted time-series analysis. J Trauma Acute Care Surg. 2021 04 01; 90(4):700-707. Matthay ZA, Kornblith AE, Matthay EC, Sedaghati M, Peterson S, Boeck M, Bongiovanni T, Campbell A, Chalwell L, Colwell C, Farrell MS, Kim WC, Knudson MM, Mackersie R, Li L, Nunez-Garcia B, Langness S, Plevin RE, Sammann A, Tesoriero R, Stein DM, Kornblith LZ. PMID: 33252457; PMCID: PMC7979514.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsPHPublic Health
    15. Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation. Shock. 2021 02 01; 55(2):189-197. Fields AT, Matthay ZA, Nunez-Garcia B, Matthay EC, Bainton RJ, Callcut RA, Kornblith LZ. PMID: 32694397; PMCID: PMC8547718.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    16. Dynamic effects of calcium on in vivo and ex vivo platelet behavior after trauma. J Trauma Acute Care Surg. 2020 11; 89(5):871-879. Matthay ZA, Fields AT, Nunez-Garcia B, Patel MH, Cohen MJ, Callcut RA, Kornblith LZ. PMID: 32852184; PMCID: PMC7830742.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    17. Identification of injury and shock driven effects on ex vivo platelet aggregometry: A cautionary tale of phenotyping. J Trauma Acute Care Surg. 2020 07; 89(1):20-28. Starr NE, Matthay ZA, Fields AT, Nunez-Garcia B, Callcut RA, Cohen MJ, Kornblith LZ. PMID: 32218020; PMCID: PMC7386285.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    18. A journey upstream: Fluctuating platelet-specific genes in cell-free plasma as proof-of-concept for using ribonucleic acid sequencing to improve understanding of postinjury platelet biology. J Trauma Acute Care Surg. 2020 06; 88(6):742-751. Kornblith LZ, Bainton CMV, Fields AT, Matthay ZA, Magid NT, Nunez-Garcia B, Prakash A, Kurien PA, Callcut RA, Cohen MJ, Bainton RJ. PMID: 32195992; PMCID: PMC7571783.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    19. Von Willebrand factor as a thrombotic and inflammatory mediator in critical illness. Transfusion. 2020 06; 60 Suppl 3:S158-S166. Plautz WE, Matthay ZA, Rollins-Raval MA, Raval JS, Kornblith LZ, Neal MD. PMID: 32478907; PMCID: PMC9053104.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    20. Thefeasibility, appropriateness, and applicability of trauma scoring systems in low and middle-income countries: a systematic review. Trauma Surg Acute Care Open. 2020; 5(1):e000424. Feldhaus I, Carvalho M, Waiz G, Igu J, Matthay Z, Dicker R, Juillard C. PMID: 32420451; PMCID: PMC7223475.
      View in: PubMed   Mentions: 6  
    21. Specification of implementation interventions to address the cascade of HIV care and treatment in resource-limited settings: a systematic review. Implement Sci. 2017 08 08; 12(1):102. Hickey MD, Odeny TA, Petersen M, Neilands TB, Padian N, Ford N, Matthay Z, Hoos D, Doherty M, Beryer C, Baral S, Geng EH. PMID: 28784155; PMCID: PMC5547499.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    22. Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):186-92. Su X, Lee JW, Matthay ZA, Mednick G, Uchida T, Fang X, Gupta N, Matthay MA. PMID: 17431097; PMCID: PMC1976545.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    23. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med. 2006 May 01; 173(9):1008-15. Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, Makita K, Mednick G, Matthay ZA, Matthay MA. PMID: 16456142; PMCID: PMC2662912.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansAnimals
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