Alexander Lin, MD, MBA, MSc

Title(s)Professor, Surgery
SchoolSchool of Medicine
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    Collapse Education and Training
    Olin Business School, Washington University, St. Louis, MOMBA12/2020Master of Business Administration
    Children’s Hospital of Pittsburgh (CHP), University of Pittsburgh Medical Center (UPMC), Pittsburg, PA06/2010Fellowship: Craniofacial, Maxillofacial, and Pediatric Plastic Surgery
    Massachusetts General Hospital (MGH), Harvard Medical School, Boston, MA06/2007Research Fellowship: Vascular Immunobiology
    University of California San Francisco (UCSF), San Francisco, CA06/2009Residency: General Surgery and Plastic & Reconstructive Surgery
    University of California San Francisco (UCSF), San Francisco, CA06/2003Internship: General Surgery and Plastic & Reconstructive Surgery
    Johns Hopkins University School of Medicine, Baltimore, MDMD05/2002Medical School: M.D. with Alpha Omega Alpha (AOA) honors
    Stanford University, Stanford, CAMS06/1996Graduate: Master of Science, M.S. in Statistics
    Stanford University, Stanford, CABA06/1996Undergraduate: Bachelor of Arts, A.B. in Psychology with Distinction

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Transforming Cleft Speech Assessment and Care through Online Crowdsourcing.
    2020 Translational and Innovation Research Grant - Plastic Surgery Foundation (PSF) 701655Jun 1, 2020 - Jul 31, 2021
    Primary Closure versus Delayed Primary Closure: Analysis of Wound Healing Complications in Acute Traumatic Wounds.
    Saint Louis University internal grant GME Housestaff Grant award. (Caitlin Francoisse MD) Jul 1, 2019 - Jun 30, 2020
    Perceptual Factors in Female Anatomy Through Novel Crowdsourcing Analysis.
    Aesthetic Surgery Education and Research Foundation Grant (ASERF). Jul 1, 2019 - Jun 30, 2020
    Innovative Cleft Speech Assessment with Online Crowdsourcing.
    AOA Carolyn L. Kuckein Student Research Fellowship Grant 2019. (Anne Sescleifer) Jul 1, 2019 - Jun 30, 2020
    Funding for the Kids' Inpatient Database (KID) developed by the healthcare cost and utilization project.
    Saint Louis University internal grant Spark Microgrant. (Dr. Osazuwa-Peters, Dr. Hinyard, Dr. Ward, Dr. Lin, Dr. Bray, Dr. Pannu, Dr. Buchanan and Dr. GropleR) Jun 30, 2019 - Aug 31, 2019
    3D-Printing Techniques with MRI: can surgical planning be done without radiation to children?
    Saint Louis University internal grant for Medical Student Summer Research Training Program. (Chu Hyun “June” Kim) Jun 1, 2018 - Jul 31, 2018
    Pediatric Innovation Center
    Saint Louis University internal grant Big Ideas Innovation Grant. Apr 1, 2018 - Dec 31, 2019
    Crowdsourcing for cleft lip-palate outcomes.
    Saint Louis University internal grant for Medical Student Summer Research Training Program. (Anne Sescleifer) Jun 1, 2017 - Jul 31, 2017
    Preliminary Translational Testing of a Cryogel Scaffold to Promote Bone Regeneration for the Treatment of Cleft-Craniofacial Defects.
    Saint Louis University internal grant Health Sciences Grand Opportunity Review Committee. (Scott Sell PhD, Principal Investigator) Mar 1, 2017 - Mar 31, 2018
    Volumetric assessment of BMP-2 cleft airways.
    Saint Louis University internal grant for Medical Student Summer Research Training Program. (Dave Ho) Jun 1, 2016 - Jul 31, 2016
    Dental development in BMP-2 treated clefts.
    Saint Louis University internal grant for Medical Student Summer Research Training Program. (Larry Rudolf) Jun 1, 2015 - Jul 31, 2015
    Sleep apnea and orthodontics in children with clefts.
    Saint Louis University internal grant for Medical Student Summer Research Training Program. (Justine McGauley and Hannah Polus) Jun 1, 2014 - Jul 31, 2014
    BMP-2 alveolar bone reconstruction in the growing facial skeleton.
    2013 National Endowment for Plastic Surgery Grant – Plastic Surgery Foundation (PSF) 273520Aug 1, 2013 - Sep 30, 2015
    Head shape outcomes in deformational plagiocephaly.
    Saint Louis University internal grant for Medical Student Summer Research Training Program. (Emma Kulig) Award Jun 1, 2013 - Jul 31, 2013
    Speech outcomes in cleft palate surgery.
    Saint Louis University internal grant for Medical Student Summer Research Training Program. (Thomas Gildea) Jun 1, 2012 - Jul 31, 2012
    PTSD, Injury, and Pain from Intimate Partner Violence: Psychophysiological Assessment.
    16086
    Role: Collaborator
    Craniosynostosis Outcomes.
    22068
    Craniosynostosis Outcomes.
    22068
    Genes that Influence Mandibular Size.
    22150
    Role: Collaborator
    Plagiocephaly: Analyses and Outcomes.
    22228
    Effects of Medications on Surgical Results.
    22762
    BMP-2 Alveolar Bone Reconstruction in the Growing Facial Skeleton.
    23523
    Growth and Airway Outcomes of Cleft Patients.
    24620
    Squamosal Craniosynostosis.
    27209
    Speech Outcomes in Cleft Palate Surgery.
    27328
    Cleft Lip-Nose-Palate Outcomes Analyzed by Crowdsourcing.
    28444
    Crowdsourcing to Assess Speech Outcomes in Cleft Palate Surgery.
    28839
    Defining the Ideal Vulva: A Population Analysis.
    29405
    3D-Printed Customized Titanium Plates in Le Fort I Maxillary Advancement.
    29598
    Infection Rates for Delayed versus Primary Closure of Wounds.
    30110

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Surgical Management in Isolated Squamosal Craniosynostosis: A Systematic Review. Ann Plast Surg. 2023 10 01; 91(4):493-496. Fallahian F, Meyer A, Tadisina KK, Lin AY. PMID: 37553899.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. The Role of Postoperative Nasal Stents in Cleft Rhinoplasty: A Systematic Review. Cleft Palate Craniofac J. 2023 Jul 28; 10556656231190703. Nguyen DC, Myint JA, Lin AY. PMID: 37501651.
      View in: PubMed   Mentions: 1     Fields:    
    3. Seeing Cleft Lip from a New Angle: Crowdsourcing to Determine whether Scar Severity or Lip Angle Matters More to the General Public. Plast Reconstr Surg. 2023 07 01; 152(1):126e-133e. Sescleifer AM, Francoisse CA, Osborn TA, Rector JD, Lin AY. PMID: 36728477.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Defining Ideal External Female Genital Anatomy via Crowdsourcing Analysis. Aesthet Surg J. 2022 04 12; 42(5):505-515. Frojo G, Kareh AM, Probst KX, Rector JD, Plikaitis CM, Lund HG, Lin AY. PMID: 34374739.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Three-dimensional printing in medicine: a systematic review of pediatric applications. Pediatr Res. 2021 02; 89(3):415-425. Francoisse CA, Sescleifer AM, King WT, Lin AY. PMID: 32503028.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Plastic Surgery Innovation with 3D Printing for Craniomaxillofacial Operations. Mo Med. 2020 Mar-Apr; 117(2):136-142. Lin AY, Yarholar LM. PMID: 32308239; PMCID: PMC7144700.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Preparing for the Plastic Surgery In-Service Exam: Evidence-Based Essentials for the Plastic Surgery Resident. Plast Reconstr Surg. 2019 01; 143(1):256e-257e. Frojo G, Tadisina KK, Kaswan S, Doston A, Lin AY. PMID: 30303932.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Tissue Engineering Scaffolds Fabricated in Dissolvable 3D-Printed Molds for Patient-Specific Craniofacial Bone Regeneration. J Funct Biomater. 2018 Jul 24; 9(3). de la Lastra AA, Hixon KR, Aryan L, Banks AN, Lin AY, Hall AF, Sell SA. PMID: 30042357; PMCID: PMC6165179.
      View in: PubMed   Mentions: 4  
    9. Systematic Review: Online Crowdsourcing to Assess Perceptual Speech Outcomes. J Surg Res. 2018 12; 232:351-364. Sescleifer AM, Francoisse CA, Lin AY. PMID: 30463741.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    10. Demystifying the "Triple Point: " Technical Nuances of the Fronto-Orbital Advancement. J Craniofac Surg. 2018 May; 29(3):796-799. Lopez CD, Kumar A, Lin AY, Bonfield CM, Weinzweig J, Naidich T, Smith CM, Taub PJ. PMID: 29489569.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Temporomandibular Joint Septic Arthritis. Plast Reconstr Surg Glob Open. 2018 Jan; 6(1):e1648. Frojo G, Tadisina KK, Shetty V, Lin AY. PMID: 29464173; PMCID: PMC5811303.
      View in: PubMed   Mentions: 4  
    12. Squamosal Craniosynostosis: Defining the Phenotype and Indications for Surgical Management. Ann Plast Surg. 2017 Nov; 79(5):458-466. Tadisina KK, Lin AY. PMID: 28953518.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Cryogel scaffolds from patient-specific 3D-printed molds for personalized tissue-engineered bone regeneration in pediatric cleft-craniofacial defects. J Biomater Appl. 2017 Nov; 32(5):598-611. Hixon KR, Melvin AM, Lin AY, Hall AF, Sell SA. PMID: 28980856.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    14. A New Classification of Three-Dimensional Printing Technologies: Systematic Review of Three-Dimensional Printing for Patient-Specific Craniomaxillofacial Surgery. Plast Reconstr Surg. 2017 May; 139(5):1211-1220. Jacobs CA, Lin AY. PMID: 28445375.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    15. The Plastic Surgery Match: A Quantitative Analysis of Applicant Impressions From the Interview Visit. Ann Plast Surg. 2016 Dec; 77(6):587-591. Frojo G, Tadisina KK, Pressman Z, Chibnall JT, Lin AY, Kraemer BA. PMID: 27740953.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Management of Patients With Positional Plagiocephaly: The Role of Physical Therapy. Neurosurgery. 2016 Nov; 79(5):E630-E631. Baird LC, Klimo P, Flannery AM, Bauer DF, Beier A, Durham S, Lin AY, McClung-Smith C, Mitchell L, Nikas D, Tamber MS, Tyagi R, Mazzola C. PMID: 27759674.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Diagnosis of Patients With Positional Plagiocephaly: The Role of Imaging. Neurosurgery. 2016 Nov; 79(5):E625-E626. Mazzola C, Baird LC, Bauer DF, Beier A, Durham S, Klimo P, Lin AY, McClung-Smith C, Mitchell L, Nikas D, Tamber MS, Tyagi R, Flannery AM. PMID: 27776086.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Diagnosis of Patients With Positional Plagiocephaly: The Role of Imaging. Neurosurgery. 2016 Nov; 79(5):E625-E626. Mazzola C, Baird LC, Bauer DF, Beier A, Durham S, Klimo P, Lin AY, McClung-Smith C, Mitchell L, Nikas D, Tamber MS, Tyagi R, Flannery AM. PMID: 27759672.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Management of Patients With Positional Plagiocephaly: The Role of Repositioning. Neurosurgery. 2016 Nov; 79(5):E627-E629. Klimo P, Lingo PR, Baird LC, Bauer DF, Beier A, Durham S, Lin AY, McClung-Smith C, Mitchell L, Nikas D, Tamber MS, Tyagi R, Mazzola C, Flannery AM. PMID: 27776087.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Role of Cranial Molding Orthosis (Helmet) Therapy for Patients With Positional Plagiocephaly. Neurosurgery. 2016 Nov; 79(5):E632-E633. Tamber MS, Nikas D, Beier A, Baird LC, Bauer DF, Durham S, Klimo P, Lin AY, Mazzola C, McClung-Smith C, Mitchell L, Tyagi R, Flannery AM. PMID: 27776089.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    21. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Management of Patients With Positional Plagiocephaly: Executive Summary. Neurosurgery. 2016 Nov; 79(5):623-624. Flannery AM, Tamber MS, Mazzola C, Klimo P, Baird LC, Tyagi R, Bauer DF, Beier A, Durham S, Lin AY, McClung-Smith C, Mitchell L, Nikas D. PMID: 27759671.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    22. Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Role of Cranial Molding Orthosis (Helmet) Therapy for Patients With Positional Plagiocephaly. Neurosurgery. 2016 Nov; 79(5):E632-E633. Tamber MS, Nikas D, Beier A, Baird LC, Bauer DF, Durham S, Klimo P, Lin AY, Mazzola C, McClung-Smith C, Mitchell L, Tyagi R, Flannery AM. PMID: 27759675.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    23. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Management of Patients With Positional Plagiocephaly: The Role of Physical Therapy. Neurosurgery. 2016 Nov; 79(5):E630-E631. Baird LC, Klimo P, Flannery AM, Bauer DF, Beier A, Durham S, Lin AY, McClung-Smith C, Mitchell L, Nikas D, Tamber MS, Tyagi R, Mazzola C. PMID: 27776088.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    24. Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Management of Patients With Positional Plagiocephaly: The Role of Repositioning. Neurosurgery. 2016 Nov; 79(5):E627-E629. Klimo P, Lingo PR, Baird LC, Bauer DF, Beier A, Durham S, Lin AY, McClung-Smith C, Mitchell L, Nikas D, Tamber MS, Tyagi R, Mazzola C, Flannery AM. PMID: 27759673.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    25. Development of Volunteer International Craniofacial Surgery Missions: The Komedyplast Protocol. J Craniofac Surg. 2015 Jun; 26(4):1151-5. Taub PJ, Lin AY, Cladis FP, Baker SB, Gooden CK, Kumar A, Losee JE, Menard R, Starks R, Duncan JA, De Pawlikowski W, Cecchi AW, Weinzweig J. PMID: 26080146.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Custom porous polyethylene implants for large-scale pediatric skull reconstruction: early outcomes. J Craniofac Surg. 2012 Jan; 23(1):67-70. Lin AY, Kinsella CR, Rottgers SA, Smith DM, Grunwaldt LJ, Cooper GM, Losee JE. PMID: 22337376.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    27. Rhinoplasty sizers. Aesthetic Plast Surg. 2012 Feb; 36(1):72-6. McMahon D, Lin A, Reddy V, Gruber RP. PMID: 21938594.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circ Res. 2011 Sep 02; 109(6):616-28. Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD, Dedhar S, Parmacek MS, Gerszten RE. PMID: 21778429; PMCID: PMC3351207.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    29. BMP-2-mediated regeneration of large-scale cranial defects in the canine: an examination of different carriers. Plast Reconstr Surg. 2011 May; 127(5):1865-1873. Kinsella CR, Bykowski MR, Lin AY, Cray JJ, Durham EL, Smith DM, DeCesare GE, Mooney MP, Cooper GM, Losee JE. PMID: 21532416.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    30. Acellular dermal matrix in the treatment and prevention of exposed vertical expandable prosthetic titanium ribs. Spine (Phila Pa 1976). 2011 Apr 15; 36(8):E563-7. Gill R, Kinsella CR, Lin AY, Grunwaldt LJ, Jiang S, Deeney VF, Losee J. PMID: 21242878.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Nasal strips for evaluating and classifying valvular nasal obstruction. Aesthetic Plast Surg. 2011 Apr; 35(2):211-5. Gruber RP, Lin AY, Richards T. PMID: 21082181; PMCID: PMC3068252.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. A predictive test and classification for valvular nasal obstruction using nasal strips. Plast Reconstr Surg. 2010 Jul; 126(1):143-145. Gruber RP, Lin AY, Richards T. PMID: 20595865.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation. Atherosclerosis. 2010 May; 210(1):107-13. Kristo F, Hardy GJ, Anderson TJ, Sinha S, Ahluwalia N, Lin AY, Passeri J, Scherrer-Crosbie M, Gerszten RE. PMID: 20035940; PMCID: PMC2862127.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    34. Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture. Circulation. 2009 Jan 27; 119(3):426-35. King VL, Lin AY, Kristo F, Anderson TJ, Ahluwalia N, Hardy GJ, Owens AP, Howatt DA, Shen D, Tager AM, Luster AD, Daugherty A, Gerszten RE. PMID: 19139386; PMCID: PMC2765043.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    35. Inhibited aortic aneurysm formation in BLT1-deficient mice. J Immunol. 2007 Jul 01; 179(1):691-7. Ahluwalia N, Lin AY, Tager AM, Pruitt IE, Anderson TJ, Kristo F, Shen D, Cruz AR, Aikawa M, Luster AD, Gerszten RE. PMID: 17579092.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    36. Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells. Circulation. 2006 May 16; 113(19):2301-12. Heller EA, Liu E, Tager AM, Yuan Q, Lin AY, Ahluwalia N, Jones K, Koehn SL, Lok VM, Aikawa E, Moore KJ, Luster AD, Gerszten RE. PMID: 16682613.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
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