Ali Yousefian Jazi, PhD

Title(s)ASST RES, Neurology
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #215
San Francisco CA 94158
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    Seoul National University, Seoul, South KoreaPhD03/2020Bioengineering
    Korea Institute of Science and Technology, Seoul, South KoreaPost-Doc07/2025Neuroscience

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Astrocytic noncanonical WNT5B signaling modulates extracellular matrix remodeling and neuropathology in Huntington's disease. Signal Transduct Target Ther. 2026 Jan 19; 11(1):23. Nguyen PTT, Yousefian-Jazi A, Hyeon SJ, Lee S, Kim SC, Park U, Jeong Y, Kim S, Kim S, Kim Y, Ryu HL, Lee KE, Stein TD, Myers RH, Hwang EM, Lee J, Ryu H. PMID: 41549079; PMCID: PMC12812802.
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    2. Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice. Mol Neurodegener. 2025 Feb 07; 20(1):16. Yousefian-Jazi A, Kim S, Chu J, Choi SH, Nguyen PTT, Park U, Kim MG, Hwang H, Lee K, Kim Y, Hyeon SJ, Rhim H, Ryu HL, Lim G, Stein TD, Lim K, Ryu H, Lee J. PMID: 39920775; PMCID: PMC11806887.
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    3. Astrocytic autophagy plasticity modulates Aß clearance and cognitive function in Alzheimer's disease. Mol Neurodegener. 2024 Jul 23; 19(1):55. Kim S, Chun H, Kim Y, Kim Y, Park U, Chu J, Bhalla M, Choi SH, Yousefian-Jazi A, Kim S, Hyeon SJ, Kim S, Kim Y, Ju YH, Lee SE, Lee H, Lee K, Oh SJ, Hwang EM, Lee J, Lee CJ, Ryu H. PMID: 39044253; PMCID: PMC11267931.
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    4. Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice. bioRxiv. 2024 Jul 17. Yousefian-Jazi A, Kim S, Choi SH, Chu J, Nguyen PT, Park U, Lim K, Hwang H, Lee K, Kim Y, Hyeon SJ, Rhim H, Ryu HL, Lim G, Stein TD, Ryu H, Lee J. PMID: 39071309; PMCID: PMC11275751.
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    5. Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALS. J Biomed Sci. 2022 Dec 20; 29(1):106. Choi SH, Yousefian-Jazi A, Hyeon SJ, Nguyen PTT, Chu J, Kim S, Kim S, Ryu HL, Kowall NW, Ryu H, Lee J. PMID: 36536341; PMCID: PMC9764677.
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    6. Non-Cell Autonomous and Epigenetic Mechanisms of Huntington's Disease. Int J Mol Sci. 2021 Nov 19; 22(22). Kim C, Yousefian-Jazi A, Choi SH, Chang I, Lee J, Ryu H. PMID: 34830381; PMCID: PMC8617801.
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    7. Power Failure of Mitochondria and Oxidative Stress in Neurodegeneration and Its Computational Models. Antioxidants (Basel). 2021 Feb 03; 10(2). Woo J, Cho H, Seol Y, Kim SH, Park C, Yousefian-Jazi A, Hyeon SJ, Lee J, Ryu H. PMID: 33546471; PMCID: PMC7913624.
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    8. Pathogenic Genome Signatures That Damage Motor Neurons in Amyotrophic Lateral Sclerosis. Cells. 2020 Dec 15; 9(12). Yousefian-Jazi A, Seol Y, Kim J, Ryu HL, Lee J, Ryu H. PMID: 33333804; PMCID: PMC7765192.
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    9. Functional fine-mapping of noncoding risk variants in amyotrophic lateral sclerosis utilizing convolutional neural network. Sci Rep. 2020 Jul 30; 10(1):12872. Yousefian-Jazi A, Sung MK, Lee T, Hong YH, Choi JK, Choi J. PMID: 32732921; PMCID: PMC7393092.
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    10. Functional annotation of noncoding causal variants in autoimmune diseases. Genomics. 2020 Mar; 112(2):1208-1213. Yousefian-Jazi A, Jung J, Choi JK, Choi J. PMID: 31295546.
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    11. Sequential Integration of Fuzzy Clustering and Expectation Maximization for Transcription Factor Binding Site Identification. J Comput Biol. 2018 Nov; 25(11):1247-1256. Yousefian-Jazi A, Choi J. PMID: 30133315.
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