Avisek Majumder, PhD

Title(s)Associate Specialist, Medicine
SchoolSchool of Medicine
Address1450 Third Street, #322
San Francisco CA 94158
Phone415-353-7070
PronounsHe/Him/His
ORCID ORCID Icon0000-0002-6761-2242 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California San Francisco, USAPostdoctoral Employee12/2023Breast Cancer
    University of Louisville, USAPhD12/2018Biochemistry and Molecular Genetics
    University of Louisville, USAMS2017Biochemistry and Molecular Genetics
    West Bengal University of Technology , IndiaMS2010Genetic Engineering
    Collapse Awards and Honors
    ASBMB2018American Society for Biochemistry and Molecular Biology (ASBMB) travel award
    Endocrine Society2013Endocrine Society Early career forum travel grant
    Department of Biotechnology; Ministry of Science and Technology2013Department of Biotechnology Full travel award

    Collapse Overview 
    Collapse Overview
    My main research focus is to understand how HER3 (a member of the EGRF/HER family of receptor tyrosine kinases) functions in physiologic signaling and how this function is perturbed in cancer cells. In one project, I’m doing structure-function studies of HER2 and HER3 in HER2-positive breast cancer to identify new structural features that are critical for signaling so that we can develop a new generation of drugs that are both highly effective and have fewer side effects than the current treatment regimen for these patients. In another project, I’m working on the development of novel SynNotch CART cell therapy to target HER2-positive breast tumors. Apart from these, I am also involved with several other projects that are currently going on in our lab

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    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Pivotal Role of One-Carbon Metabolism in Neoplastic Progression During the Aging Process. Biomolecules. 2024 Oct 31; 14(11). Majumder A, Bano S, Nayak KB. PMID: 39595564; PMCID: PMC11591851.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. Deciphering the Potentials of Cardamom in Cancer Prevention and Therapy: From Kitchen to Clinic. Biomolecules. 2024 Sep 18; 14(9). Bano S, Majumder A, Srivastava A, Nayak KB. PMID: 39334932; PMCID: PMC11430645.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    3. How the Western Diet Thwarts the Epigenetic Efforts of Gut Microbes in Ulcerative Colitis and Its Association with Colorectal Cancer. Biomolecules. 2024 May 29; 14(6). Majumder A, Bano S. PMID: 38927037; PMCID: PMC11201633.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    4. Evolving CAR-T-Cell Therapy for Cancer Treatment: From Scientific Discovery to Cures. Cancers (Basel). 2023 Dec 20; 16(1). Majumder A. PMID: 38201467; PMCID: PMC10777914.
      View in: PubMed   Mentions: 4  
    5. HER3: Toward the Prognostic Significance, Therapeutic Potential, Current Challenges, and Future Therapeutics in Different Types of Cancer. Cells. 2023 10 25; 12(21). Majumder A. PMID: 37947595; PMCID: PMC10648638.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    6. Targeting Homocysteine and Hydrogen Sulfide Balance as Future Therapeutics in Cancer Treatment. Antioxidants (Basel). 2023 Jul 29; 12(8). Majumder A. PMID: 37627515; PMCID: PMC10451792.
      View in: PubMed   Mentions: 9  
    7. The role of HER2 and HER3 in HER2-amplified cancers beyond breast cancers. Sci Rep. 2021 04 27; 11(1):9091. Majumder A, Sandhu M, Banerji D, Steri V, Olshen A, Moasser MM. PMID: 33907275; PMCID: PMC8079373.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    8. Effect of MMP-9 gene knockout on retinal vascular form and function. Physiol Genomics. 2019 12 01; 51(12):613-622. George AK, Homme RP, Majumder A, Tyagi SC, Singh M. PMID: 31709889; PMCID: PMC6962592.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    9. Genes and genetics in hyperhomocysteinemia and the "1-carbon metabolism": implications for retinal structure and eye functions. Can J Physiol Pharmacol. 2020 Feb; 98(2):51-60. George AK, Majumder A, Ice H, Homme RP, Eyob W, Tyagi SC, Singh M. PMID: 31369712.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    10. Hydrogen sulfide intervention in cystathionine-β-synthase mutant mouse helps restore ocular homeostasis. Int J Ophthalmol. 2019; 12(5):754-764. George AK, Homme RP, Majumder A, Laha A, Metreveli N, Sandhu HS, Tyagi SC, Singh M. PMID: 31131233; PMCID: PMC6520274.
      View in: PubMed   Mentions: 16  
    11. Expression Analysis of the Circular RNA Molecules in the Human Retinal Cells Treated with Homocysteine. Curr Eye Res. 2019 03; 44(3):287-293. Singh M, George AK, Homme RP, Majumder A, Laha A, Sandhu HS, Tyagi SC. PMID: 30369271; PMCID: PMC6709669.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    12. Circular RNAs constitute an inherent gene regulatory axis in the mammalian eye and brain 1. Can J Physiol Pharmacol. 2019 Jun; 97(6):463-472. George AK, Master K, Majumder A, Homme RP, Laha A, Sandhu HS, Tyagi SC, Singh M. PMID: 30444648.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    13. Restoration of skeletal muscle homeostasis by hydrogen sulfide during hyperhomocysteinemia-mediated oxidative/ER stress condition 1. Can J Physiol Pharmacol. 2019 Jun; 97(6):441-456. Majumder A, Singh M, George AK, Tyagi SC. PMID: 30422673; PMCID: PMC6719301.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    14. Remote ischemic conditioning as a cytoprotective strategy in vasculopathies during hyperhomocysteinemia: An emerging research perspective. J Cell Biochem. 2019 01; 120(1):77-92. Majumder A, Singh M, George AK, Homme RP, Laha A, Tyagi SC. PMID: 30272816.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    15. Remodeling of Retinal Architecture in Diabetic Retinopathy: Disruption of Ocular Physiology and Visual Functions by Inflammatory Gene Products and Pyroptosis. Front Physiol. 2018; 9:1268. Homme RP, Singh M, Majumder A, George AK, Nair K, Sandhu HS, Tyagi N, Lominadze D, Tyagi SC. PMID: 30233418; PMCID: PMC6134046.
      View in: PubMed   Mentions: 29  
    16. Hydrogen sulfide improves postischemic neoangiogenesis in the hind limb of cystathionine-β-synthase mutant mice via PPAR-γ/VEGF axis. Physiol Rep. 2018 09; 6(17):e13858. Majumder A, Singh M, George AK, Behera J, Tyagi N, Tyagi SC. PMID: 30175474; PMCID: PMC6119702.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    17. Hydrogen sulfide alleviates hyperhomocysteinemia-mediated skeletal muscle atrophy via mitigation of oxidative and endoplasmic reticulum stress injury. Am J Physiol Cell Physiol. 2018 11 01; 315(5):C609-C622. Majumder A, Singh M, Behera J, Theilen NT, George AK, Tyagi N, Metreveli N, Tyagi SC. PMID: 30110564; PMCID: PMC6293052.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    18. Connecting homocysteine and obesity through pyroptosis, gut microbiome, epigenetics, peroxisome proliferator-activated receptor γ, and zinc finger protein 407. Can J Physiol Pharmacol. 2018 Oct; 96(10):971-976. Laha A, Majumder A, Singh M, Tyagi SC. PMID: 29890083.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    19. Circular RNAs profiling in the cystathionine-β-synthase mutant mouse reveals novel gene targets for hyperhomocysteinemia induced ocular disorders. Exp Eye Res. 2018 09; 174:80-92. Singh M, George AK, Homme RP, Majumder A, Laha A, Sandhu HS, Tyagi SC. PMID: 29803556.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    20. A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration. Int J Ophthalmol. 2018; 11(5):881-887. George AK, Singh M, Homme RP, Majumder A, Sandhu HS, Tyagi SC. PMID: 29862191; PMCID: PMC5957044.
      View in: PubMed   Mentions: 19  
    21. Post-menopausal breast cancer: from estrogen to androgen receptor. Oncotarget. 2017 Nov 24; 8(60):102739-102758. Majumder A, Singh M, Tyagi SC. PMID: 29254284; PMCID: PMC5731994.
      View in: PubMed   Mentions: 20     Fields:    
    22. Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy. J Cell Biochem. 2017 08; 118(8):2108-2117. Majumder A, Behera J, Jeremic N, Tyagi SC. PMID: 27982479; PMCID: PMC6563903.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
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