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Interlocking G-Quadruplexes Using a G-Triad•G Connection: Implications for G-Wire Assembly. J Am Chem Soc. 2024 Sep 25; 146(38):26034-26040.
Singh A, Winnerdy FR, Avila CA, Nogues C, Phan AT, Heddi B. PMID: 39276075.
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Cells
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Functional and Promiscuity Studies of Three-Residue Cyclophane Forming Enzymes Show Nonnative C-C Cross-Linked Products and Leader-Dependent Cyclization. ACS Chem Biol. 2024 03 15; 19(3):774-783.
Suarez AFL, Nguyen TQN, Chang L, Tooh YW, Yong RHS, Leow LC, Koh IYF, Chen H, Koh JWH, Selvanayagam A, Lim V, Tan YE, Agatha I, Winnerdy FR, Morinaka BI. PMID: 38417140.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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RNA is a key component of extracellular DNA networks in Pseudomonas aeruginosa biofilms. Nat Commun. 2023 Nov 27; 14(1):7772.
Mugunthan S, Wong LL, Winnerdy FR, Summers S, Bin Ismail MH, Foo YH, Jaggi TK, Meldrum OW, Tiew PY, Chotirmall SH, Rice SA, Phan AT, Kjelleberg S, Seviour T. PMID: 38012164; PMCID: PMC10682433.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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Stitched peptides as potential cell permeable inhibitors of oncogenic DAXX protein. RSC Chem Biol. 2023 Nov 29; 4(12):1096-1110.
Jelinska C, Kannan S, Frosi Y, Ramlan SR, Winnerdy F, Lakshminarayanan R, Johannes CW, Brown CJ, Phan AT, Rhodes D, Verma CS. PMID: 38033728; PMCID: PMC10685803.
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Stable bulged G-quadruplexes in the human genome: identification, experimental validation and functionalization. Nucleic Acids Res. 2023 05 22; 51(9):4148-4177.
Papp C, Mukundan VT, Jenjaroenpun P, Winnerdy FR, Ow GS, Phan AT, Kuznetsov VA. PMID: 37094040; PMCID: PMC10201450.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex. Biochem Biophys Res Commun. 2022 07 12; 613:153-158.
Ngo KH, Liew CW, Lattmann S, Winnerdy FR, Phan AT. PMID: 35561583.
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Cells
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Four-Layered Intramolecular Parallel G-Quadruplex with Non-Nucleotide Loops: An Ultra-Stable Self-Folded DNA Nano-Scaffold. ACS Nano. 2022 01 25; 16(1):533-540.
Devi G, Winnerdy FR, Ang JCY, Lim KW, Phan AT. PMID: 34927423.
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Cells
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Unprecedented hour-long residence time of a cation in a left-handed G-quadruplex. Chem Sci. 2021 Apr 26; 12(20):7151-7157.
Winnerdy FR, Bakalar B, Das P, Heddi B, Marchand A, Rosu F, Gabelica V, Phan AT. PMID: 34123342; PMCID: PMC8153214.
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2
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Duplexes Formed by G4C2 Repeats Contain Alternate Slow- and Fast-Flipping G·G Base Pairs. Biochemistry. 2021 Apr 13; 60(14):1097-1107.
Maity A, Winnerdy FR, Chen G, Phan AT. PMID: 33750098.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The biofilm matrix scaffold of Pseudomonas aeruginosa contains G-quadruplex extracellular DNA structures. NPJ Biofilms Microbiomes. 2021 03 19; 7(1):27.
Seviour T, Winnerdy FR, Wong LL, Shi X, Mugunthan S, Foo YH, Castaing R, Adav SS, Subramoni S, Kohli GS, Shewan HM, Stokes JR, Rice SA, Phan AT, Kjelleberg S. PMID: 33741996; PMCID: PMC7979868.
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PubMed Mentions:
26 Fields:
Translation:
Cells
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A novel minimal motif for left-handed G-quadruplex formation. Chem Commun (Camb). 2021 Mar 09; 57(20):2527-2530.
Das P, Winnerdy FR, Maity A, Mechulam Y, Phan AT. PMID: 33690751.
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PubMed Mentions:
4 Fields:
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Bulges in left-handed G-quadruplexes. Nucleic Acids Res. 2021 02 22; 49(3):1724-1736.
Das P, Ngo KH, Winnerdy FR, Maity A, Bakalar B, Mechulam Y, Schmitt E, Phan AT. PMID: 33503265; PMCID: PMC7897477.
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8 Fields:
Translation:
Cells
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Coexistence of two quadruplex-duplex hybrids in the PIM1 gene. Nucleic Acids Res. 2020 11 04; 48(19):11162-11171.
Tan DJY, Winnerdy FR, Lim KW, Phan AT. PMID: 32976598; PMCID: PMC7641742.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Post-translational formation of strained cyclophanes in bacteria. Nat Chem. 2020 11; 12(11):1042-1053.
Nguyen TQN, Tooh YW, Sugiyama R, Nguyen TPD, Purushothaman M, Leow LC, Hanif K, Yong RHS, Agatha I, Winnerdy FR, Gugger M, Phan AT, Morinaka BI. PMID: 32807886.
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31 Fields:
Translation:
Cells
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Guanine anchoring: a strategy for specific targeting of a G-quadruplex using short PNA, LNA and DNA molecules. Chem Commun (Camb). 2020 Jun 02; 56(44):5897-5900.
Tan DJY, Das P, Winnerdy FR, Lim KW, Phan AT. PMID: 32338660.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs. Nucleic Acids Res. 2020 04 06; 48(6):3315-3327.
Maity A, Winnerdy FR, Chang WD, Chen G, Phan AT. PMID: 32100003; PMCID: PMC7102960.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Extracellular protein isolation from the matrix of anammox biofilm using ionic liquid extraction. Appl Microbiol Biotechnol. 2020 Apr; 104(8):3643-3654.
Wong LL, Natarajan G, Boleij M, Thi SS, Winnerdy FR, Mugunthan S, Lu Y, Lee JM, Lin Y, van Loosdrecht M, Law Y, Kjelleberg S, Seviour T. PMID: 32095864.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter. Nucleic Acids Res. 2020 02 20; 48(3):1120-1130.
Wang ZF, Li MH, Chu IT, Winnerdy FR, Phan AT, Chang TC. PMID: 31912153; PMCID: PMC7026657.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Solution Structures of a G-Quadruplex Bound to Linear- and Cyclic-Dinucleotides. J Am Chem Soc. 2019 11 13; 141(45):18038-18047.
Winnerdy FR, Das P, Heddi B, Phan AT. PMID: 31661272.
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10 Fields:
Translation:
Cells
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NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res. 2019 09 05; 47(15):8272-8281.
Winnerdy FR, Bakalar B, Maity A, Vandana JJ, Mechulam Y, Schmitt E, Phan AT. PMID: 31216034; PMCID: PMC6735952.
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16 Fields:
Translation:
Cells
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An Unprecedented Knot-like G-Quadruplex Peripheral Motif. Angew Chem Int Ed Engl. 2019 09 23; 58(39):13834-13839.
Truong THA, Winnerdy FR, Phan AT. PMID: 31317601.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Bright G-Quadruplex Nanostructures Functionalized with Porphyrin Lanterns. J Am Chem Soc. 2019 08 14; 141(32):12582-12591.
Pathak P, Yao W, Hook KD, Vik R, Winnerdy FR, Brown JQ, Gibb BC, Pursell ZF, Phan AT, Jayawickramarajah J. PMID: 31322869; PMCID: PMC8170694.
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12 Fields:
Translation:
Cells
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Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter. Nucleic Acids Res. 2019 02 20; 47(3):1564-1572.
Sengar A, Vandana JJ, Chambers VS, Di Antonio M, Winnerdy FR, Balasubramanian S, Phan AT. PMID: 30551210; PMCID: PMC6379715.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids. J Am Chem Soc. 2018 11 07; 140(44):14528-14532.
Nadai M, Doria F, Scalabrin M, Pirota V, Grande V, Bergamaschi G, Amendola V, Winnerdy FR, Phan AT, Richter SN, Freccero M. PMID: 30351011; PMCID: PMC6242190.
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18 Fields:
Translation:
Cells
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Analysis of Interactions between Telomeric i-Motif DNA and a Cyclic Tetraoxazole Compound. Chembiochem. 2018 11 02; 19(21):2268-2272.
Sedghi Masoud S, Yamaoki Y, Ma Y, Marchand A, Winnerdy FR, Gabelica V, Phan AT, Katahira M, Nagasawa K. PMID: 30160816.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Rotation of Guanine Amino Groups in G-Quadruplexes: A Probe for Local Structure and Ligand Binding. Biophys J. 2017 Aug 22; 113(4):775-784.
Adrian M, Winnerdy FR, Heddi B, Phan AT. PMID: 28834714; PMCID: PMC5567425.
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PubMed Mentions:
7 Fields:
Translation:
Cells