Hanna Martens, PhD

Title(s)Assistant Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th Street, #N312F
San Francisco CA 94158
ORCID ORCID Icon0000-0001-8910-1999 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Padua, ItalyPostDoc07/2023Mechanobiology
    EMBL, Heidelberg, GermanyPh.D.02/2016Developmental Biology
    Heidelberg University, GermanyM.Sc.11/2011Molecular Biotechnology
    Heidelberg University, GermanyB.Sc.08/2009Molecular Biotechnology

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    Collapse Overview
    The Martens lab is interested in the mechanisms of tissue aging with a specific focus on connective tissue compartments that serve as structural pillars of organ architecture. Our work demonstrated a central requirement for the active engagement of cellular mechanotransduction pathways in maintaining youthful organ homeostasis by limiting cellular senescence and inflammatory signaling in mechanically challenged tissue compartments (doi.org/10.1038/s41586-022-04924-6). Building on this concept, we are striving to investigate the role and importance of structural tissue compartments to the maintenance of a youthful tissue state. A special focus is understanding how aging stromal niches impact the plasticity, survival and mitotic potential of resident somatic stem cell populations and progenitor cell pools.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS-STING. Nature. 2022 07; 607(7920):790-798. Sladitschek-Martens HL, Guarnieri A, Brumana G, Zanconato F, Battilana G, Xiccato RL, Panciera T, Forcato M, Bicciato S, Guzzardo V, Fassan M, Ulliana L, Gandin A, Tripodo C, Foiani M, Brusatin G, Cordenonsi M, Piccolo S. PMID: 35768505; PMCID: PMC7613988.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    2. Mechanosignaling in vertebrate development. Dev Biol. 2022 08; 488:54-67. Piccolo S, Sladitschek-Martens HL, Cordenonsi M. PMID: 35580730.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    3. Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context. Stem Cell Reports. 2022 02 08; 17(2):231-244. Russo L, Sladitschek HL, Neveu PA. PMID: 35063128; PMCID: PMC8828549.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Editorial: The Role of Epigenetic Modifications in Cancer Progression. Front Oncol. 2020; 10:617178. Fujimura A, Pei H, Zhang H, Sladitschek HL, Chang L. PMID: 33489924; PMCID: PMC7820891.
      View in: PubMed   Mentions: 2  
    5. Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in Glioblastoma. Nat Cancer. 2021 02; 2(2):174-188. Castellan M, Guarnieri A, Fujimura A, Zanconato F, Battilana G, Panciera T, Sladitschek HL, Contessotto P, Citron A, Grilli A, Romano O, Bicciato S, Fassan M, Porcù E, Rosato A, Cordenonsi M, Piccolo S. PMID: 33644767; PMCID: PMC7116831.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    6. MorphoSeq: Full Single-Cell Transcriptome Dynamics Up to Gastrulation in a Chordate. Cell. 2020 05 14; 181(4):922-935.e21. Sladitschek HL, Fiuza UM, Pavlinic D, Benes V, Hufnagel L, Neveu PA. PMID: 32315617; PMCID: PMC7237864.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    7. A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit. Mol Syst Biol. 2019 12; 15(12):e9043. Sladitschek HL, Neveu PA. PMID: 31885203; PMCID: PMC6896232.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    8. Author Correction: Resonant out-of-phase fluorescence microscopy and remote imaging overcome spectral limitations. Nat Commun. 2017 12 14; 8(1):2173. Quérard J, Zhang R, Kelemen Z, Plamont MA, Xie X, Chouket R, Roemgens I, Korepina Y, Albright S, Ipendey E, Volovitch M, Sladitschek HL, Neveu P, Gissot L, Gautier A, Faure JD, Croquette V, Le Saux T, Jullien L. PMID: 29242600; PMCID: PMC5730614.
      View in: PubMed   Mentions: 1     Fields:    
    9. Resonant out-of-phase fluorescence microscopy and remote imaging overcome spectral limitations. Nat Commun. 2017 10 17; 8(1):969. Quérard J, Zhang R, Kelemen Z, Plamont MA, Xie X, Chouket R, Roemgens I, Korepina Y, Albright S, Ipendey E, Volovitch M, Sladitschek HL, Neveu P, Gissot L, Gautier A, Faure JD, Croquette V, Le Saux T, Jullien L. PMID: 29042541; PMCID: PMC5645393.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    10. Integrated Experimental and Theoretical Studies of Stem Cells. Curr Stem Cell Rep. 2017; 3(3):248-252. Sladitschek HL, Neveu PA. PMID: 28845388; PMCID: PMC5548823.
      View in: PubMed   Mentions:
    11. Dynamic multicolor protein labeling in living cells. Chem Sci. 2017 Aug 01; 8(8):5598-5605. Li C, Plamont MA, Sladitschek HL, Rodrigues V, Aujard I, Neveu P, Le Saux T, Jullien L, Gautier A. PMID: 28970939; PMCID: PMC5618792.
      View in: PubMed   Mentions: 35  
    12. Bidirectional Promoter Engineering for Single Cell MicroRNA Sensors in Embryonic Stem Cells. PLoS One. 2016; 11(5):e0155177. Sladitschek HL, Neveu PA. PMID: 27152616; PMCID: PMC4859538.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    13. The bimodally expressed microRNA miR-142 gates exit from pluripotency. Mol Syst Biol. 2015 Dec 21; 11(12):850. Sladitschek HL, Neveu PA. PMID: 26690966; PMCID: PMC4704488.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    14. MXS-Chaining: A Highly Efficient Cloning Platform for Imaging and Flow Cytometry Approaches in Mammalian Systems. PLoS One. 2015; 10(4):e0124958. Sladitschek HL, Neveu PA. PMID: 25909630; PMCID: PMC4409215.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
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