-
Electrodiagnostic Findings in Riboflavin Transporter Deficiency Type 2. J Clin Neuromuscul Dis. 2022 Jun 01; 23(4):205-209.
Sanchez JA, Traub R, Trau SP, Howard JF. PMID: 35608644.
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PubMed Mentions: Fields:
Translation:
Humans
-
Selected clinical and demographic factors and all-cause mortality among individuals with Duchenne muscular dystrophy in the Muscular Dystrophy Surveillance, Tracking, and Research Network. Neuromuscul Disord. 2022 06; 32(6):468-476.
Paramsothy P, Wang Y, Cai B, Conway KM, Johnson NE, Pandya S, Ciafaloni E, Mathews KD, Romitti PA, Howard JF, Riley C. PMID: 35597713; PMCID: PMC9214635.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial. JAMA. 2022 04 19; 327(15):1456-1468.
Guglieri M, Bushby K, McDermott MP, Hart KA, Tawil R, Martens WB, Herr BE, McColl E, Speed C, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Willis T, Griggs RC, FOR-DMD Investigators of the Muscle Study Group, Straub V, van Ruiten H, Childs AM, Ciafaloni E, Shieh PB, Spinty S, Maggi L, Baranello G, Butterfield RJ, Horrocks IA, Roper H, Alhaswani Z, Flanigan KM, Kuntz NL, Manzur A, Darras BT, Kang PB, Morrison L, Krzesniak-Swinarska M, Mah JK, Mongini TE, Ricci F, von der Hagen M, Finkel RS, O'Reardon K, Wicklund M, Kumar A, McDonald CM, Han JJ, Joyce N, Henricson EK, Schara-Schmidt U, Gangfuss A, Wilichowski E, Barohn RJ, Statland JM, Campbell C, Vita G, Vita GL, Howard JF, Hughes I, McMillan HJ, Pegoraro E, Bello L, Burnette WB, Thangarajh M, Chang T. PMID: 35381069; PMCID: PMC8984930.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
Wang Y, Guo L, Yin X, McCarthy EC, Cheng MI, Hoang AT, Chen HC, Patel AY, Allard Trout D, Xu E, Yakobian N, Hugo W, Howard JF, Sheu KM, Hoffmann A, Lechner MG, Su MA. PMID: 35058362; PMCID: PMC8795502.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Role Attainment in Emerging Adulthood: Subjective Evaluation by Male Adolescents and Adults with Duchenne and Becker Muscular Dystrophy. J Neuromuscul Dis. 2022; 9(3):447-456.
Peay HL, Do BT, Khosla N, Paramsothy P, Erickson SW, Lamb MM, Whitehead N, Fox DJ, Pandya S, Kinnett K, Wolff J, Howard JF. PMID: 35275556; PMCID: PMC9126318.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
A Case of MuSK Myasthenia Gravis Presenting With Persistent Respiratory Insufficiency. J Clin Neuromuscul Dis. 2021 Sep 01; 23(1):39-42.
Tsai C, Howard JF, Mehrabyan A. PMID: 34431800.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Cellular changes in eculizumab early responders with generalized myasthenia gravis. Clin Immunol. 2021 10; 231:108830.
Li Y, Yi JS, Howard JF, Chopra M, Russo MA, Guptill JT. PMID: 34450290.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Telemedicine visits in myasthenia gravis: Expert guidance and the Myasthenia Gravis Core Exam (MG-CE). Muscle Nerve. 2021 09; 64(3):270-276.
Guidon AC, Muppidi S, Nowak RJ, Guptill JT, Hehir MK, Ruzhansky K, Burton LB, Post D, Cutter G, Conwit R, Mejia NI, Kaminski HJ, Howard JF. PMID: 33959997; PMCID: PMC9057373.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT): a multicentre, randomised, placebo-controlled, phase 3 trial. Lancet Neurol. 2021 07; 20(7):526-536.
Howard JF, Bril V, Vu T, Karam C, Peric S, Margania T, Murai H, Bilinska M, Shakarishvili R, Smilowski M, Guglietta A, Ulrichts P, Vangeneugden T, Utsugisawa K, Verschuuren J, Mantegazza R, ADAPT Investigator Study Group. PMID: 34146511.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCTClinical Trials
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Long-term efficacy of eculizumab in refractory generalized myasthenia gravis: responder analyses. Ann Clin Transl Neurol. 2021 07; 8(7):1398-1407.
Howard JF, Karam C, Yountz M, O'Brien FL, Mozaffar T, REGAIN Study Group. PMID: 34043280; PMCID: PMC8283175.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Zilucoplan: An Investigational Complement C5 Inhibitor for the Treatment of Acetylcholine Receptor Autoantibody-Positive Generalized Myasthenia Gravis. Expert Opin Investig Drugs. 2021 May; 30(5):483-493.
Howard JF, Vissing J, Gilhus NE, Leite MI, Utsugisawa K, Duda PW, Farzaneh-Far R, Murai H, Wiendl H. PMID: 33792453.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Reduced plasmablast frequency is associated with seronegative myasthenia gravis. Muscle Nerve. 2021 04; 63(4):577-585.
Guptill JT, Barfield R, Chan C, Russo MA, Emmett D, Raja S, Massey JM, Juel VC, Hobson-Webb LD, Gable KL, Gonzalez N, Hammett A, Howard JF, Chopra M, Kaminski HJ, Siddiqi ZA, Migdal M, Yi JS. PMID: 33294984; PMCID: PMC8100987.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
COVID-19-associated risks and effects in myasthenia gravis (CARE-MG). Lancet Neurol. 2020 12; 19(12):970-971.
Muppidi S, Guptill JT, Jacob S, Li Y, Farrugia ME, Guidon AC, Tavee JO, Kaminski H, Howard JF, Cutter G, Wiendl H, Maas MB, Illa I, Mantegazza R, Murai H, Utsugisawa K, Nowak RJ, CARE-MG Study Group. PMID: 33212055; PMCID: PMC7837033.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study. Front Neurol. 2020; 11:556104.
Nowak RJ, Muppidi S, Beydoun SR, O'Brien FL, Yountz M, Howard JF. PMID: 33329303; PMCID: PMC7732596.
View in:
PubMed Mentions:
4
-
Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension. Neurology. 2021 01 26; 96(4):e610-e618.
Mantegazza R, Wolfe GI, Muppidi S, Wiendl H, Fujita KP, O'Brien FL, Booth HDE, Howard JF, REGAIN Study Group. PMID: 33229455; PMCID: PMC7905790.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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Epidemiological evidence for a hereditary contribution to myasthenia gravis: a retrospective cohort study of patients from North America. BMJ Open. 2020 09 18; 10(9):e037909.
Green JD, Barohn RJ, Bartoccion E, Benatar M, Blackmore D, Chaudhry V, Chopra M, Corse A, Dimachkie MM, Evoli A, Florence J, Freimer M, Howard JF, Jiwa T, Kaminski HJ, Kissel JT, Koopman WJ, Lipscomb B, Maestri M, Marino M, Massey JM, McVey A, Mezei MM, Muppidi S, Nicolle MW, Oger J, Pascuzzi RM, Pasnoor M, Pestronk A, Provenzano C, Ricciardi R, Richman DP, Rowin J, Sanders DB, Siddiqi Z, Soloway A, Wolfe GI, Wulf C, Drachman DB, Traynor BJ. PMID: 32948566; PMCID: PMC7511637.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Accuracy of the Scratch Collapse Test for Carpal Tunnel Syndrome in Comparison With Electrodiagnostic Studies. Hand (N Y). 2022 07; 17(4):630-634.
Areson DG, Filer WG, Harris MG, Howard JF, Shuping LT, Traub R. PMID: 32698624; PMCID: PMC9274899.
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PubMed Mentions: Fields:
Translation:
Humans
-
Consistent improvement with eculizumab across muscle groups in myasthenia gravis. Ann Clin Transl Neurol. 2020 08; 7(8):1327-1339.
Mantegazza R, O'Brien FL, Yountz M, Howard JF, REGAIN study group. PMID: 32700461; PMCID: PMC7448154.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCTClinical Trials
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Response to: Eculizumab package insert recommendations for meningococcal vaccinations: call for clarity and a targeted approach for use of the drug in neuromyelitis optica spectrum disorder. CNS Spectr. 2021 06; 26(3):195-196.
Pittock SJ, Weitz I, Howard JF, Sabatella G, Mehta S, Franklin J. PMID: 32641193.
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PubMed Mentions:
2 Fields:
Translation:
HumansPHPublic Health
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Clinical features of LRP4/agrin-antibody-positive myasthenia gravis: A multicenter study. Muscle Nerve. 2020 09; 62(3):333-343.
Rivner MH, Quarles BM, Pan JX, Yu Z, Howard JF, Corse A, Dimachkie MM, Jackson C, Vu T, Small G, Lisak RP, Belsh J, Lee I, Nowak RJ, Baute V, Scelsa S, Fernandes JA, Simmons Z, Swenson A, Barohn R, Sanka RB, Gooch C, Ubogu E, Caress J, Pasnoor M, Xu H, Mei L. PMID: 32483837; PMCID: PMC7496236.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Complement Inhibitor Therapy for Myasthenia Gravis. Front Immunol. 2020; 11:917.
Albazli K, Kaminski HJ, Howard JF. PMID: 32582144; PMCID: PMC7283905.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
-
Imbalance in T follicular helper cells producing IL-17 promotes pro-inflammatory responses in MuSK antibody positive myasthenia gravis. J Neuroimmunol. 2020 08 15; 345:577279.
Li Y, Guptill JT, Russo MA, Howard JF, Massey JM, Juel VC, Hobson-Webb LD, Emmett D, Chopra M, Raja S, Liu W, Yi JS. PMID: 32497931; PMCID: PMC7397478.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Response to eculizumab in patients with myasthenia gravis recently treated with chronic IVIg: a subgroup analysis of REGAIN and its open-label extension study. Ther Adv Neurol Disord. 2020; 13:1756286420911784.
Jacob S, Murai H, Utsugisawa K, Nowak RJ, Wiendl H, Fujita KP, O'Brien F, Howard JF. PMID: 32426038; PMCID: PMC7222230.
View in:
PubMed Mentions:
5
-
Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial. JAMA Neurol. 2020 05 01; 77(5):582-592.
Howard JF, Nowak RJ, Wolfe GI, Freimer ML, Vu TH, Hinton JL, Benatar M, Duda PW, MacDougall JE, Farzaneh-Far R, Kaminski HJ, Zilucoplan MG Study Group, Barohn R, Dimachkie M, Pasnoor M, Farmakidis C, Liu T, Colgan S, Benatar MG, Bertorini T, Pillai R, Henegar R, Bromberg M, Gibson S, Janecki T, Freimer M, Elsheikh B, Matisak P, Genge A, Guidon A, David W, Habib AA, Mathew V, Mozaffar T, Hinton JL, Hewitt W, Barnett D, Sullivan P, Ho D, Howard JF, Traub RE, Chopra M, Kaminski HJ, Aly R, Bayat E, Abu-Rub M, Khan S, Lange D, Holzberg S, Khatri B, Lindman E, Olapo T, Sershon LM, Lisak RP, Bernitsas E, Jia K, Malik R, Lewis-Collins TD, Nicolle M, Nowak RJ, Sharma A, Roy B, Nye J, Pulley M, Berger A, Shabbir Y, Sachdev A, Patterson K, Siddiqi Z, Sivak M, Bratton J, Small G, Kohli A, Fetter M, Vu T, Lam L, Harvey B, Wolfe GI, Silvestri N, Patrick K, Zakalik K, Duda PW, MacDougall J, Farzaneh-Far R, Pontius A, Hoarty M. PMID: 32065623; PMCID: PMC7042797.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCTClinical Trials
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Guidance for the management of myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) during the COVID-19 pandemic. J Neurol Sci. 2020 05 15; 412:116803.
International MG/COVID-19 Working Group, Jacob S, Muppidi S, Guidon A, Guptill J, Hehir M, Howard JF, Illa I, Mantegazza R, Murai H, Utsugisawa K, Vissing J, Wiendl H, Nowak RJ. PMID: 32247193; PMCID: PMC7105910.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCellsPHPublic Health
-
'Minimal symptom expression' in patients with acetylcholine receptor antibody-positive refractory generalized myasthenia gravis treated with eculizumab. J Neurol. 2020 Jul; 267(7):1991-2001.
Vissing J, Jacob S, Fujita KP, O'Brien F, Howard JF, REGAIN study group. PMID: 32189108; PMCID: PMC7320935.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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Clinical outcome measures following plasma exchange for MG exacerbation. Ann Clin Transl Neurol. 2019 10; 6(10):2114-2119.
Raja SM, Howard JF, Juel VC, Massey JM, Chopra M, Guptill JT. PMID: 31560178; PMCID: PMC6801175.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Correction to: Eculizumab improves fatigue in refractory generalized myasthenia gravis. Qual Life Res. 2019 Aug; 28(8):2255.
Andersen H, Mantegazza R, Wang JJ, O'Brien F, Patra K, Howard JF, REGAIN Study Group. PMID: 31115842; PMCID: PMC6620249.
View in:
PubMed Mentions: Fields:
-
Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis. Neurology. 2019 06 04; 92(23):e2661-e2673.
Howard JF, Bril V, Burns TM, Mantegazza R, Bilinska M, Szczudlik A, Beydoun S, Garrido FJRR, Piehl F, Rottoli M, Van Damme P, Vu T, Evoli A, Freimer M, Mozaffar T, Ward ES, Dreier T, Ulrichts P, Verschueren K, Guglietta A, de Haard H, Leupin N, Verschuuren JJGM, Efgartigimod MG Study Group. PMID: 31118245; PMCID: PMC6556100.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCTClinical Trials
-
Eculizumab improves fatigue in refractory generalized myasthenia gravis. Qual Life Res. 2019 Aug; 28(8):2247-2254.
Andersen H, Mantegazza R, Wang JJ, O'Brien F, Patra K, Howard JF, REGAIN Study Group. PMID: 30905021; PMCID: PMC6620379.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCTClinical Trials
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Long-term safety and efficacy of eculizumab in generalized myasthenia gravis. Muscle Nerve. 2019 07; 60(1):14-24.
Muppidi S, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Nowak RJ, Andersen H, Casasnovas C, de Bleecker JL, Vu TH, Mantegazza R, O'Brien FL, Wang JJ, Fujita KP, Howard JF, Regain Study Group. PMID: 30767274; PMCID: PMC6619057.
View in:
PubMed Mentions:
66 Fields:
Translation:
Humans
-
Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis. Muscle Nerve. 2019 04; 59(4):404-410.
Clifford KM, Hobson-Webb LD, Benatar M, Burns TM, Barnett C, Silvestri NJ, Howard JF, Visser A, Crum BA, Nowak R, Beekman R, Kumar A, Ruzhansky K, Chen IA, Pulley MT, Laboy SM, Fellman MA, Howard DB, Kolb NA, Greene SM, Pasnoor M, Dimachkie MM, Barohn RJ, Hehir MK. PMID: 30575980.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Tacrolimus inhibits Th1 and Th17 responses in MuSK-antibody positive myasthenia gravis patients. Exp Neurol. 2019 02; 312:43-50.
Li Y, Guptill JT, Russo MA, Massey JM, Juel VC, Hobson-Webb LD, Howard JF, Chopra M, Liu W, Yi JS. PMID: 30472069; PMCID: PMC6390960.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Circulating microRNA plasma profile in MuSK+ myasthenia gravis. J Neuroimmunol. 2018 12 15; 325:87-91.
Sabre L, Guptill JT, Russo M, Juel VC, Massey JM, Howard JF, Hobson-Webb LD, Punga AR. PMID: 30316681; PMCID: PMC6240475.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Schwann cell-derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment. J Clin Invest. 2018 10 01; 128(10):4727-4741.
Allard DE, Wang Y, Li JJ, Conley B, Xu EW, Sailer D, Kimpston C, Notini R, Smith CJ, Koseoglu E, Starmer J, Zeng XL, Howard JF, Hoke A, Scherer SS, Su MA. PMID: 30222134; PMCID: PMC6159985.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
In Vivo Viscoelastic Response (VisR) Ultrasound for Characterizing Mechanical Anisotropy in Lower-Limb Skeletal Muscles of Boys with and without Duchenne Muscular Dystrophy. Ultrasound Med Biol. 2018 12; 44(12):2519-2530.
Moore CJ, Caughey MC, Meyer DO, Emmett R, Jacobs C, Chopra M, Howard JF, Gallippi CM. PMID: 30174231; PMCID: PMC6215506.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Correlation between myasthenia gravis-activities of daily living (MG-ADL) and quantitative myasthenia gravis (QMG) assessments of anti-acetylcholine receptor antibody-positive refractory generalized myasthenia gravis in the phase 3 regain study. Muscle Nerve. 2018 08; 58(2):E21-E22.
Vissing J, O'Brien F, Wang JJ, Howard JF. PMID: 29684239.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
A checklist for clinical trials in rare disease: obstacles and anticipatory actions-lessons learned from the FOR-DMD trial. Trials. 2018 May 10; 19(1):291.
Crow RA, Hart KA, McDermott MP, Tawil R, Martens WB, Herr BE, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Hirtz D, Lochmuller H, Straub V, Ciafaloni E, Shieh PB, Spinty S, Childs AM, Manzur AY, Morandi L, Butterfield RJ, Horrocks I, Roper H, Flanigan KM, Kuntz NL, Mah JK, Morrison L, Darras BT, von der Hagen M, Schara U, Wilichowski E, Mongini T, McDonald CM, Vita G, Barohn RJ, Finkel RS, Wicklund M, McMillan HJ, Hughes I, Pegoraro E, Bryan Burnette W, Howard JF, Thangarajh M, Campbell C, Griggs RC, Bushby K, Guglieri M. PMID: 29793540; PMCID: PMC5968578.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Distinct representation of muscle weakness in QMG and MG-ADL - Authors' reply. Lancet Neurol. 2018 03; 17(3):205-206.
Howard JF, O'Brien F, Wang JJ. PMID: 29452680.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
IL-10 Paradoxically Promotes Autoimmune Neuropathy through S1PR1-Dependent CD4+ T Cell Migration. J Immunol. 2018 03 01; 200(5):1580-1592.
Smith CJ, Allard DE, Wang Y, Howard JF, Montgomery SA, Su MA. PMID: 29367208; PMCID: PMC5821539.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Myasthenia gravis: the role of complement at the neuromuscular junction. Ann N Y Acad Sci. 2018 01; 1412(1):113-128.
Howard JF. PMID: 29266249.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
-
Learning from the past: reflections on recently completed myasthenia gravis trials. Ann N Y Acad Sci. 2018 01; 1412(1):5-13.
Benatar M, Howard JF, Barohn R, Wolfe GI, Cutter G. PMID: 29064567; PMCID: PMC5790606.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. Lancet Neurol. 2017 12; 16(12):976-986.
Howard JF, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Muppidi S, Nowak RJ, O'Brien F, Wang JJ, Mantegazza R, REGAIN Study Group. PMID: 29066163.
View in:
PubMed Mentions:
158 Fields:
Translation:
HumansCTClinical Trials
-
Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review. Neurology. 2017 Sep 05; 89(10):1069-1077.
Hehir MK, Hobson-Webb LD, Benatar M, Barnett C, Silvestri NJ, Howard JF, Howard D, Visser A, Crum BA, Nowak R, Beekman R, Kumar A, Ruzhansky K, Chen IA, Pulley MT, LaBoy SM, Fellman MA, Greene SM, Pasnoor M, Burns TM. PMID: 28801338.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
The Relationship between Trans-Lesional Conduction, Motor Neuron Pool Excitability, and Motor Function in Dogs with Incomplete Recovery from Severe Spinal Cord Injury. J Neurotrauma. 2017 11 01; 34(21):2994-3002.
Lewis MJ, Howard JF, Olby NJ. PMID: 28462632; PMCID: PMC6436022.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Brachial Plexus Injury in a 6-Year-Old Boy with 100% Displaced Proximal Humeral Metaphyseal Fracture: A Case Presentation. PM R. 2017 12; 9(12):1294-1298.
Jovanovich EN, Howard JF. PMID: 28606839.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Marked clinical and jitter improvement after eculizumab in refractory myasthenia. Muscle Nerve. 2017 09; 56(3):E16-E18.
Juel VC, Sanders DB, Hobson-Webb LD, Massey JM, Guptill JT, O'Brien F, Wang JJ, Howard JF. PMID: 28214342.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Developing standardized corticosteroid treatment for Duchenne muscular dystrophy. Contemp Clin Trials. 2017 07; 58:34-39.
Guglieri M, Bushby K, McDermott MP, Hart KA, Tawil R, Martens WB, Herr BE, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Willis T, Hirtz D, Shieh PB, Straub V, Childs AM, Ciafaloni E, Butterfield RJ, Horrocks I, Spinty S, Flanigan KM, Kuntz NL, Baranello G, Roper H, Morrison L, Mah JK, Manzur AY, McDonald CM, Schara U, von der Hagen M, Barohn RJ, Campbell C, Darras BT, Finkel RS, Vita G, Hughes I, Mongini T, Pegoraro E, Wicklund M, Wilichowski E, Bryan Burnette W, Howard JF, McMillan HJ, Thangarajh M, Griggs RC. PMID: 28450193; PMCID: PMC6279424.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
QMG and MG-ADL correlations: Study of eculizumab treatment of myasthenia gravis. Muscle Nerve. 2017 08; 56(2):328-330.
Howard JF, Freimer M, O'Brien F, Wang JJ, Collins SR, Kissel JT, MG (Phase2) Study Group. PMID: 28010051.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCTClinical Trials
-
Seronegative myasthenia gravis associated with malignant thymoma. Neuromuscul Disord. 2017 May; 27(5):417-418.
Richards J, Howard JF. PMID: 28238572.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis. Autoimmunity. 2016 11; 49(7):472-479.
Guptill JT, Juel VC, Massey JM, Anderson AC, Chopra M, Yi JS, Esfandiari E, Buchanan T, Smith B, Atherfold P, Jones E, Howard JF. PMID: 27684107; PMCID: PMC5440840.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis. Neurology. 2016 Jul 05; 87(1):57-64.
Pasnoor M, He J, Herbelin L, Burns TM, Nations S, Bril V, Wang AK, Elsheikh BH, Kissel JT, Saperstein D, Shaibani JA, Jackson C, Swenson A, Howard JF, Goyal N, David W, Wicklund M, Pulley M, Becker M, Mozaffar T, Benatar M, Pazcuzzi R, Simpson E, Rosenfeld J, Dimachkie MM, Statland JM, Barohn RJ, Methotrexate in MG Investigators of the Muscle Study Group. PMID: 27306628; PMCID: PMC4932232.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
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Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine. Muscle Nerve. 2016 Feb; 53(2):165-8.
Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM, Hehir MK, Hobson-Webb LD, Howard JF, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Shieh PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI. PMID: 26662952.
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2 Fields:
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Humans
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Late-onset Becker muscular dystrophy: Refining the clinical features and electrophysiological findings. Muscle Nerve. 2015 Nov; 52(5):885-7.
Beltran Papsdorf T, Howard JF, Chahin N. PMID: 26179421.
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Humans
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High-Pressure Transvenous Perfusion of the Upper Extremity in Human Muscular Dystrophy: A Safety Study with 0.9% Saline. Hum Gene Ther. 2015 Sep; 26(9):614-21.
Fan Z, Kocis K, Valley R, Howard JF, Chopra M, Chen Y, An H, Lin W, Muenzer J, Powers W. PMID: 25953425; PMCID: PMC4575535.
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11 Fields:
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Humans
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A genome-wide association study of myasthenia gravis. JAMA Neurol. 2015 Apr; 72(4):396-404.
Renton AE, Pliner HA, Provenzano C, Evoli A, Ricciardi R, Nalls MA, Marangi G, Abramzon Y, Arepalli S, Chong S, Hernandez DG, Johnson JO, Bartoccioni E, Scuderi F, Maestri M, Gibbs JR, Errichiello E, Chiò A, Restagno G, Sabatelli M, Macek M, Scholz SW, Corse A, Chaudhry V, Benatar M, Barohn RJ, McVey A, Pasnoor M, Dimachkie MM, Rowin J, Kissel J, Freimer M, Kaminski HJ, Sanders DB, Lipscomb B, Massey JM, Chopra M, Howard JF, Koopman WJ, Nicolle MW, Pascuzzi RM, Pestronk A, Wulf C, Florence J, Blackmore D, Soloway A, Siddiqi Z, Muppidi S, Wolfe G, Richman D, Mezei MM, Jiwa T, Oger J, Drachman DB, Traynor BJ. PMID: 25643325; PMCID: PMC4856525.
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49 Fields:
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Humans
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Characterization of B cells in muscle-specific kinase antibody myasthenia gravis. Neurol Neuroimmunol Neuroinflamm. 2015 Apr; 2(2):e77.
Guptill JT, Yi JS, Sanders DB, Guidon AC, Juel VC, Massey JM, Howard JF, Scuderi F, Bartoccioni E, Evoli A, Weinhold KJ. PMID: 25745635; PMCID: PMC4345633.
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25 Fields:
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Pearls & Oy-sters: clues to the diagnosis of adult-onset acid maltase deficiency. Neurology. 2014 Mar 04; 82(9):e73-5.
Beltran Papsdorf TB, Howard JF, Chahin N. PMID: 24590251; PMCID: PMC3945654.
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1 Fields:
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Humans
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The effect of sacral neuromodulation on pudendal nerve function and female sexual function. Neurourol Urodyn. 2015 Jun; 34(5):456-60.
Parnell BA, Howard JF, Geller EJ. PMID: 24615871.
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10 Fields:
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HumansCTClinical Trials
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A randomized, double-blind, placebo-controlled phase II study of eculizumab in patients with refractory generalized myasthenia gravis. Muscle Nerve. 2013 Jul; 48(1):76-84.
Howard JF, Barohn RJ, Cutter GR, Freimer M, Juel VC, Mozaffar T, Mellion ML, Benatar MG, Farrugia ME, Wang JJ, Malhotra SS, Kissel JT, MG Study Group. PMID: 23512355.
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72 Fields:
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HumansCTClinical Trials
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Divergent effects of T cell costimulation and inflammatory cytokine production on autoimmune peripheral neuropathy provoked by Aire deficiency. J Immunol. 2013 Apr 15; 190(8):3895-904.
Zeng XL, Nagavalli A, Smith CJ, Howard JF, Su MA. PMID: 23487421; PMCID: PMC3622123.
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10 Fields:
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AnimalsCells
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Electrodiagnosis of disorders of neuromuscular transmission. Phys Med Rehabil Clin N Am. 2013 Feb; 24(1):169-92.
Howard JF. PMID: 23177038.
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10 Fields:
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HumansCells
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The paradox of muscle hypertrophy in muscular dystrophy. Phys Med Rehabil Clin N Am. 2012 Feb; 23(1):149-72, xii.
Kornegay JN, Childers MK, Bogan DJ, Bogan JR, Nghiem P, Wang J, Fan Z, Howard JF, Schatzberg SJ, Dow JL, Grange RW, Styner MA, Hoffman EP, Wagner KR. PMID: 22239881; PMCID: PMC5951392.
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51 Fields:
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HumansAnimals
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Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies. Mamm Genome. 2012 Feb; 23(1-2):85-108.
Kornegay JN, Bogan JR, Bogan DJ, Childers MK, Li J, Nghiem P, Detwiler DA, Larsen CA, Grange RW, Bhavaraju-Sanka RK, Tou S, Keene BP, Howard JF, Wang J, Fan Z, Schatzberg SJ, Styner MA, Flanigan KM, Xiao X, Hoffman EP. PMID: 22218699; PMCID: PMC3911884.
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76 Fields:
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Animals
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Idiopathic intracranial hypertension in a child with Duchenne muscular dystrophy. Pediatr Neurol. 2011 Dec; 45(6):406-8.
Weig SG, Zinn MM, Howard JF. PMID: 22115006.
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Humans
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Safety and feasibility of high-pressure transvenous limb perfusion with 0.9% saline in human muscular dystrophy. Mol Ther. 2012 Feb; 20(2):456-61.
Fan Z, Kocis K, Valley R, Howard JF, Chopra M, An H, Lin W, Muenzer J, Powers W. PMID: 21772257; PMCID: PMC3278558.
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29 Fields:
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Humans
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Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs. Mol Ther. 2010 Aug; 18(8):1501-8.
Kornegay JN, Li J, Bogan JR, Bogan DJ, Chen C, Zheng H, Wang B, Qiao C, Howard JF, Xiao X. PMID: 20517298; PMCID: PMC2927072.
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94 Fields:
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HumansAnimalsCells
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Consensus statement: the use of intravenous immunoglobulin in the treatment of neuromuscular conditions report of the AANEM ad hoc committee. Muscle Nerve. 2009 Nov; 40(5):890-900.
Donofrio PD, Berger A, Brannagan TH, Bromberg MB, Howard JF, Latov N, Quick A, Tandan R. PMID: 19768755.
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33 Fields:
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Humans
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Chapter 12 Neurotoxicology of neuromuscular transmission. Handb Clin Neurol. 2008; 91:369-400.
Howard JF, Sanders DB. PMID: 18631850.
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1 Fields:
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HumansAnimalsCells
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Myokymia and neuromyotonia in a cat. J Am Vet Med Assoc. 2005 Nov 15; 227(10):1608-12, 1591.
Galano HR, Olby NJ, Howard JF, Shelton GD. PMID: 16313038.
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2 Fields:
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Animals
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Distal symmetrical polyneuropathy: a definition for clinical research. A report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. Arch Phys Med Rehabil. 2005 Jan; 86(1):167-74.
England JD, Gronseth GS, Franklin G, Miller RG, Asbury AK, Carter GT, Cohen JA, Fisher MA, Howard JF, Kinsella LJ, Latov N, Lewis RA, Low PA, Sumner AJ. PMID: 15641009.
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17 Fields:
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Humans
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Adult-Onset Presentation of Glutaric Acidemia Type II With Myopathy. J Clin Neuromuscul Dis. 2003 Mar; 4(3):124-8.
Mareska MC, Adams KK, Muenzer J, Frerman F, Braun TG, Howard JF. PMID: 19078703.
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4 Fields: