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John Ambrose, MD, FACC

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentDean's Office
Address155 N. Fresno Street
Fresno CA 93701
Phone559-459-3872
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ambrose J, Najafi A. Strategies for the prevention of coronary artery disease complications- Can we do better? Am J Med. 2018 May 02. PMID: 29729244.
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    2. Acharya T, Salisbury AC, Spertus JA, Kennedy KF, Bhullar A, Reddy HKK, Joshi BK, Ambrose J. In-Hospital Outcomes of Percutaneous Coronary Intervention in America's Safety Net: Insights From the NCDR Cath-PCI Registry. JACC Cardiovasc Interv. 2017 Aug 14; 10(15):1475-1485. PMID: 28797422.
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    3. Sharma R, Oni OA, Gupta K, Sharma M, Sharma R, Singh V, Parashara D, Kamalakar S, Dawn B, Chen G, Ambrose J, Barua RS. Normalization of Testosterone Levels After Testosterone Replacement Therapy Is Associated With Decreased Incidence of Atrial Fibrillation. J Am Heart Assoc. 2017 May 09; 6(5). PMID: 28487389.
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    4. Ambrose J, Acharya T, Roberts MJ. Finding the High-Risk Patient in Primary Prevention Is Not as Easy as a Conventional Risk Score! Am J Med. 2016 Dec; 129(12):1329.e1-1329.e7. PMID: 27566505.
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    5. Katikireddy CK, Singh M, Muhyieddeen K, Acharya T, Ambrose J, Samim A. Left Atrial Area and Right Ventricle Dimensions in Non-gated Axial Chest CT can Differentiate Pulmonary Hypertension Due to Left Heart Disease from Other Causes. J Cardiovasc Comput Tomogr. 2016 May-Jun; 10(3):246-50. PMID: 26869368.
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    6. Sharma R, Oni OA, Gupta K, Chen G, Sharma M, Dawn B, Sharma R, Parashara D, Savin VJ, Ambrose J, Barua RS. Normalization of testosterone level is associated with reduced incidence of myocardial infarction and mortality in men. Eur Heart J. 2015 Oct 21; 36(40):2706-15. PMID: 26248567.
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    7. Srikanth S, Sy F, Kotak K, Kiel RG, Bajwa M, Tandon A, Loures-Vale AA, Aftab W, Tringali S, Ambrose J. A Single Controlled Exposure to Secondhand Smoke May Not Alter Thrombogenesis or Trigger Platelet Activation. Nicotine Tob Res. 2016 May; 18(5):580-4. PMID: 26101293.
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    8. Ambrose J, Singh M. Pathophysiology of coronary artery disease leading to acute coronary syndromes. F1000Prime Rep. 2015; 7:08. PMID: 25705391; PMCID: PMC4311268.
    9. Ambrose J. Do advances in technology in the catheterization laboratory for percutaneous coronary interventions negatively influence an operator's technique, decision making, and judgment? JACC Cardiovasc Interv. 2014 Oct; 7(10):1198-9. PMID: 25240546.
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    10. Ambrose J, Acharya T. Reducing acute coronary events: the solution is not so difficult! Am J Med. 2015 Feb; 128(2):105-6. PMID: 25193272.
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    11. Ambrose J, Lardizabal J, Mouanoutoua M, Buhari CF, Berg R, Joshi B, El-Sherief K, Wessel R, Singh M, Kiel R. Femoral micropuncture or routine introducer study (FEMORIS). Cardiology. 2014; 129(1):39-43. PMID: 25012707.
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    12. Niccoli G, Stefanini GG, Capodanno D, Crea F, Ambrose J, Berg R. Are the culprit lesions severely stenotic? JACC Cardiovasc Imaging. 2013 Oct; 6(10):1108-1114. PMID: 24135324.
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    13. Sy F, Basraon J, Zheng H, Singh M, Richina J, Ambrose J. Frequency of Takotsubo cardiomyopathy in postmenopausal women presenting with an acute coronary syndrome. Am J Cardiol. 2013 Aug 15; 112(4):479-82. PMID: 23683950.
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    14. Barua RS, Ambrose J. Mechanisms of coronary thrombosis in cigarette smoke exposure. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1460-7. PMID: 23685556.
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    15. Ambrose J. Managing coronary thrombus in the cath lab during PCI. Curr Cardiol Rev. 2012 Aug; 8(3):200-1. PMID: 23210928; PMCID: PMC3465824.
    16. Srikanth S, Ambrose J. Pathophysiology of coronary thrombus formation and adverse consequences of thrombus during PCI. Curr Cardiol Rev. 2012 Aug; 8(3):168-76. PMID: 22920487; PMCID: PMC3465820.
    17. Ambrose J, Loures-Vale A, Javed U, Buhari CF, Aftab W. Angiographic correlates in type 1 and 2 MI by the universal definition. JACC Cardiovasc Imaging. 2012 Apr; 5(4):463-4. PMID: 22498337.
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    18. Ambrose J, Srikanth S. Computed tomographic angiography for localizing the site of plaque disruption/thrombus: is detection so complex? Circ Cardiovasc Imaging. 2011 Mar; 4(2):82-3. PMID: 21406660.
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    19. Lardizabal JA, Javed U, Ambrose J. Acute myocardial infarction and the five-chambered heart. Catheter Cardiovasc Interv. 2011 Feb 01; 77(2):228-31. PMID: 20853361.
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    20. Ambrose J, Buhari CF. Does angiographic response to wiring of totally occluded vessels predict outcomes in ST-segment elevation myocardial infarction? JACC Cardiovasc Interv. 2011 Jan; 4(1):63-5. PMID: 21251630.
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    21. Barua RS, Sy F, Srikanth S, Huang G, Javed U, Buhari C, Margosan D, Aftab W, Ambrose J. Acute cigarette smoke exposure reduces clot lysis--association between altered fibrin architecture and the response to t-PA. Thromb Res. 2010 Nov; 126(5):426-30. PMID: 20813396.
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    22. Sales FJ, Falcão BA, Falcão JL, Ribeiro EE, Perin MA, Horta PE, Spadaro AG, Ambrose J, Martinez EE, Furuie SS, Lemos PA. Evaluation of plaque composition by intravascular ultrasound "virtual histology": the impact of dense calcium on the measurement of necrotic tissue. EuroIntervention. 2010 Aug; 6(3):394-9. PMID: 20884420.
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    23. Lardizabal JA, Joshi BK, Ambrose J. The balance between anti-ischemic efficacy and bleeding risk of antithrombotic therapy in percutaneous coronary intervention: a Yin-Yang paradigm. J Invasive Cardiol. 2010 Jun; 22(6):284-92. PMID: 20516510.
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    24. Ambrose J, Srikanth S. Vulnerable plaques and patients: improving prediction of future coronary events. Am J Med. 2010 Jan; 123(1):10-6. PMID: 20102983.
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    25. Barua RS, Sy F, Srikanth S, Huang G, Javed U, Buhari C, Margosan D, Ambrose J. Effects of cigarette smoke exposure on clot dynamics and fibrin structure: an ex vivo investigation. Arterioscler Thromb Vasc Biol. 2010 Jan; 30(1):75-9. PMID: 19815816.
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    26. Ambrose J, Srikanth S. Preventing future acute coronary events: is the target the so-called vulnerable plaque or the high-risk or vulnerable patient? Curr Opin Cardiol. 2009 Sep; 24(5):483-9. PMID: 19550309.
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    27. Javed U, Aftab W, Ambrose J, Wessel RJ, Mouanoutoua M, Huang G, Barua RS, Weilert M, Sy F, Thatai D. Frequency of elevated troponin I and diagnosis of acute myocardial infarction. Am J Cardiol. 2009 Jul 01; 104(1):9-13. PMID: 19576313.
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    28. Friedewald VE, Ambrose J, Stone GW, Roberts WC, Willerson JT. The editor's roundtable: the vulnerable plaque. Am J Cardiol. 2008 Dec 15; 102(12):1644-53. PMID: 19064018.
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    29. Ambrose J. In search of the "vulnerable plaque": can it be localized and will focal regional therapy ever be an option for cardiac prevention? J Am Coll Cardiol. 2008 Apr 22; 51(16):1539-42. PMID: 18420095.
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    30. Srikanth S, Barua R, Ambrose J. Methamphetamine-associated acute left ventricular dysfunction: a variant of stress-induced cardiomyopathy. Cardiology. 2008; 109(3):188-92. PMID: 17728543.
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    31. Ambrose J. Myocardial ischemia and infarction. J Am Coll Cardiol. 2006 Jun 06; 47(11 Suppl):D13-7. PMID: 16750715.
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    32. Hannan EL, Racz M, Holmes DR, King SB, Walford G, Ambrose J, Sharma S, Katz S, Clark LT, Jones RH. Impact of completeness of percutaneous coronary intervention revascularization on long-term outcomes in the stent era. Circulation. 2006 May 23; 113(20):2406-12. PMID: 16702469.
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    33. Wu C, Hannan EL, Walford G, Ambrose J, Holmes DR, King SB, Clark LT, Katz S, Sharma S, Jones RH. A risk score to predict in-hospital mortality for percutaneous coronary interventions. J Am Coll Cardiol. 2006 Feb 07; 47(3):654-60. PMID: 16458151.
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    34. Liuzzo JP, Ambrose J, Coppola JT. Sirolimus- and taxol-eluting stents differ towards intimal hyperplasia and re-endothelialization. J Invasive Cardiol. 2005 Sep; 17(9):497-502. PMID: 16145242.
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    35. Hannan EL, Wu C, Walford G, King SB, Holmes DR, Ambrose J, Sharma S, Katz S, Clark LT, Jones RH. Volume-outcome relationships for percutaneous coronary interventions in the stent era. Circulation. 2005 Aug 23; 112(8):1171-9. PMID: 16103238.
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    36. Foussas SG, Zairis MN, Lyras AG, Patsourakos NG, Tsirimpis VG, Katsaros K, Beldekos DJ, Handanis SM, Mytas DZ, Karidis KS, Tselioti PG, Prekates AA, Ambrose J. Early prognostic usefulness of C-reactive protein added to the Thrombolysis In Myocardial Infarction risk score in acute coronary syndromes. Am J Cardiol. 2005 Aug 15; 96(4):533-7. PMID: 16098307.
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    37. Liuzzo JP, Ambrose J, Diggs P. Proton pump inhibitors for patients with coronary artery disease associated with reduced chest pain, emergency department visits, and hospitalizations. Clin Cardiol. 2005 Aug; 28(8):369-74. PMID: 16144212.
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    38. Ambrose J, D'Agate DJ. Plaque rupture and intracoronary thrombus in nonculprit vessels: an eyewitness account. J Am Coll Cardiol. 2005 Mar 01; 45(5):659-60. PMID: 15734607.
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    39. Ambrose J, D'Agate DJ. Classification of systemic therapies for potential stabilization of the vulnerable plaque to prevent acute myocardial infarction. Am J Cardiol. 2005 Feb 01; 95(3):379-82. PMID: 15670548.
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    40. Zairis MN, Ambrose J, Ampartzidou O, Lyras AG, Manousakis SJ, Makrygiannis SS, Beldekos DJ, Devoe MC, Fakiolas CN, Prekates AA, Olympios CD, Argyrakis SK, Foussas SG. Preprocedural plasma C-reactive protein levels, postprocedural creatine kinase-MB release, and long-term prognosis after successful coronary stenting (four-year results from the GENERATION study). Am J Cardiol. 2005 Feb 01; 95(3):386-90. PMID: 15670550.
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    41. D'Agate DJ, Patel S, Coppola JT, Ambrose J. The evolving role of glycoprotein (GP) IIb/IIIa receptor blockade during percutaneous coronary intervention of saphenous vein bypass grafts. J Invasive Cardiol. 2004 Sep; 16(9):500-3. PMID: 15353833.
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    42. Ambrose J, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol. 2004 May 19; 43(10):1731-7. PMID: 15145091.
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    43. Mandadi VR, DeVoe MC, Ambrose J, Prakash AM, Varshneya N, Gould RB, Nguyen TH, Geagea JP, Radojevic JA, Sehhat K, Barua RS. Predictors of troponin elevation after percutaneous coronary intervention. Am J Cardiol. 2004 Mar 15; 93(6):747-50. PMID: 15019883.
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    44. Heiba SI, Abdel-Dayem HM, Gould R, Bernaski E, Morlote M, El-Zeftawy H, Ambrose J. Value of low-dose dobutamine addition to routine dual isotope gated SPECT myocardial imaging in patients with healed myocardial infarction or abnormal wall thickening by echocardiogram. Am J Cardiol. 2004 Feb 01; 93(3):300-6. PMID: 14759378.
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    45. Meireles GC, Lemos PA, Ambrose J, Ribeiro E, Horta PE, Perin M, Ramires JA, Martinez EE. Luminal recovery from six to twelve months after implantation of "thicker strut" coronary stents. Am J Cardiol. 2004 Jan 15; 93(2):210-3. PMID: 14715350.
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    46. Rodriguez AE, Alemparte MR, Vigo CF, Pereira CF, Llaurado C, Russo M, Virmani R, Ambrose J. Pilot study of oral rapamycin to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial). J Invasive Cardiol. 2003 Oct; 15(10):581-4. PMID: 14519892.
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    47. Staniloae CS, Ambrose J. Identification of vulnerable atherosclerotic plaques. Expert Rev Cardiovasc Ther. 2003 Sep; 1(3):353-65. PMID: 15030264.
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    48. Ambrose J, Gould RB, Kurian DC, DeVoe MC, Pearlstein NB, Coppola JT, Siegal FP. Frequency of and outcome of acute coronary syndromes in patients with human immunodeficiency virus infection. Am J Cardiol. 2003 Aug 01; 92(3):301-3. PMID: 12888138.
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    49. Barua RS, Ambrose J, Srivastava S, DeVoe MC, Eales-Reynolds LJ. Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and upregulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells. Circulation. 2003 May 13; 107(18):2342-7. PMID: 12707237.
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    50. Zairis MN, Ambrose J, Papadaki OA, Manousakis SJ, Stefanidis AS, DeVoe MC, Handanis SM, Olympios CD, Foussas SG. C-reactive protein and ST-segment monitoring by continuous 12-lead electrocardiogram in patients with primary unstable angina pectoris. Am J Cardiol. 2003 Mar 01; 91(5):600-3. PMID: 12615271.
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    51. Puttappa R, Raia F, Bhat S, Braff R, Mandadi VR, Barua RS, DeVoe MC, Boal BH, Ambrose J. Peripheral conduction disease in left ventricular dysfunction. Am J Cardiol. 2003 Feb 01; 91(3):354-6. PMID: 12565099.
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    52. Zairis MN, Ambrose J, Manousakis SJ, Stefanidis AS, Papadaki OA, Bilianou HI, DeVoe MC, Fakiolas CN, Pissimissis EG, Olympios CD, Foussas SG. The impact of plasma levels of C-reactive protein, lipoprotein (a) and homocysteine on the long-term prognosis after successful coronary stenting: The Global Evaluation of New Events and Restenosis After Stent Implantation Study. J Am Coll Cardiol. 2002 Oct 16; 40(8):1375-82. PMID: 12392824.
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    53. Ambrose J, Gould RB, Zairis MN, DeVoe MC, Nguyen TH, Geagea JP, Arias JH, Prakash AM, Varshneya N, Meraj P, Barua RS. Acute coronary lesions and troponin elevation in unstable angina pectoris or non-ST elevation acute myocardial infarction. Am J Cardiol. 2002 Oct 01; 90(7):770-3. PMID: 12356396.
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    54. Barua RS, Ambrose J, Saha DC, Eales-Reynolds LJ. Smoking is associated with altered endothelial-derived fibrinolytic and antithrombotic factors: an in vitro demonstration. Circulation. 2002 Aug 20; 106(8):905-8. PMID: 12186791.
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    55. Barua RS, Ambrose J, Eales-Reynolds LJ, DeVoe MC, Zervas JG, Saha DC. Heavy and light cigarette smokers have similar dysfunction of endothelial vasoregulatory activity: an in vivo and in vitro correlation. J Am Coll Cardiol. 2002 Jun 05; 39(11):1758-63. PMID: 12039488.
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    56. Ambrose J, Martinez EE. A new paradigm for plaque stabilization. Circulation. 2002 Apr 23; 105(16):2000-4. PMID: 11997290.
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