 Kirsten Tolstrup, MD
 Overview Clinical Interests:
Kirsten Tolstrup is a non-invasive cardiologist with special interest in echocardiography, valvular and structural heart disease. Her clinical interests include use of transthoracic echocardiography, transesophageal and three-dimensional transesophageal echocardiography and supine bicycle stress testing with echocardiography for the evaluation of cardiovascular disease in general and valvular heart disease in particular. Dr. Tolstrup works closely with the interventional team on transcatheter based procedures such as TAVR and MitraClip.
Academic Interests:
Dr. Tolstrup’s focus is on implementation of new noninvasive procedures and development of multidisciplinary team approach to cardiovascular care. Her research interests are primarily centered around valvular heart disease and echocardiography as they relate to clinical aspects.
Bibliographic
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Lassen MCH, Biering-Sørensen SR, Olsen FJ, Skaarup KG, Tolstrup K, Qasim AN, Møgelvang R, Jensen JS, Biering-Sørensen T. Ratio of transmitral early filling velocity to early diastolic strain rate predicts long-term risk of cardiovascular morbidity and mortality in the general population. Eur Heart J. 2018 Apr 05. PMID: 29659790.
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Saric M, Armour AC, Arnaout MS, Chaudhry FA, Grimm RA, Kronzon I, Landeck BF, Maganti K, Michelena HI, Tolstrup K. Guidelines for the Use of Echocardiography in the Evaluation of a Cardiac Source of Embolism. J Am Soc Echocardiogr. 2016 Jan; 29(1):1-42. PMID: 26765302.
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Roldan CA, Schevchuck O, Tolstrup K, Roldan PC, Macias L, Qualls CR, Greene ER, Hayek R, Charlton GA, Sibbitt WL. Lambl's Excrescences: Association with Cerebrovascular Disease and Pathogenesis. Cerebrovasc Dis. 2015; 40(1-2):18-27. PMID: 26044080; PMCID: PMC4592773.
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Roldan CA, Tolstrup K, Macias L, Qualls CR, Maynard D, Charlton G, Sibbitt WL. Libman-Sacks Endocarditis: Detection, Characterization, and Clinical Correlates by Three-Dimensional Transesophageal Echocardiography. J Am Soc Echocardiogr. 2015 Jul; 28(7):770-9. PMID: 25807885; PMCID: PMC4592775.
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Tanaka J, Izumo M, Fukuoka Y, Saitoh T, Harada K, Harada K, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of two-dimensional versus real-time three-dimensional transesophageal echocardiography for evaluation of patent foramen ovale morphology. Am J Cardiol. 2013 Apr 01; 111(7):1052-6. PMID: 23352264.
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Izumo M, Shiota M, Kar S, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of real-time three-dimensional transesophageal echocardiography to two-dimensional transesophageal echocardiography for quantification of mitral valve prolapse in patients with severe mitral regurgitation. Am J Cardiol. 2013 Feb 15; 111(4):588-94. PMID: 23206924.
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Izumo M, Shiota M, Saitoh T, Kuwahara E, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Non-circular shape of right ventricular outflow tract: a real-time 3-dimensional transesophageal echocardiography study. Circ Cardiovasc Imaging. 2012 Sep 01; 5(5):621-7. PMID: 22891043.
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Saitoh T, Izumo M, Furugen A, Tanaka J, Miyata-Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Kar S, Shiota T. Echocardiographic evaluation of iatrogenic atrial septal defect after catheter-based mitral valve clip insertion. Am J Cardiol. 2012 Jun 15; 109(12):1787-91. PMID: 22475361.
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Saitoh T, Shiota M, Izumo M, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of left ventricular outflow geometry and aortic valve area in patients with aortic stenosis by 2-dimensional versus 3-dimensional echocardiography. Am J Cardiol. 2012 Jun 01; 109(11):1626-31. PMID: 22440128.
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Miyata-Fukuoka Y, Izumo M, Shimada Y, Kuwahara E, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Left atrial size and function are related to pulmonary hypertension in coronary artery disease. Echocardiography. 2012 May; 29(5):535-40. PMID: 22324451.
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Nalawadi SS, Tolstrup K, Cuk O, Shiota T, Gurudevan SV, Siegel RJ. Atropine as an adjunct to supine bicycle stress echocardiography: an alternative strategy to achieve target heart rate or rate pressure product. Eur Heart J Cardiovasc Imaging. 2012 Jul; 13(7):612-6. PMID: 22271103.
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Tolstrup K, Shiota T, Gurudevan S, Luthringer D, Luo H, Siegel RJ. Left atrial myxomas: correlation of two-dimensional and live three-dimensional transesophageal echocardiography with the clinical and pathologic findings. J Am Soc Echocardiogr. 2011 Jun; 24(6):618-24. PMID: 21367578.
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Thompson KA, Shiota T, Tolstrup K, Gurudevan SV, Siegel RJ. Utility of three-dimensional transesophageal echocardiography in the diagnosis of valvular perforations. Am J Cardiol. 2011 Jan; 107(1):100-2. PMID: 21146695.
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Gurudevan SV, Shah H, Tolstrup K, Siegel R, Krishnan SC. Septal thrombus in the left atrium: is the left atrial septal pouch the culprit? JACC Cardiovasc Imaging. 2010 Dec; 3(12):1284-6. PMID: 21163458.
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Nalawadi SS, Siegel RJ, Wolin E, Yu R, Trento A, Shiota T, Tolstrup K, Luthringer D, Gurudevan S. Morphologic features of carcinoid heart disease as assessed by three-dimensional transesophageal echocardiography. Echocardiography. 2010 Oct; 27(9):1098-105. PMID: 21039812.
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Daneshvar D, Wei J, Tolstrup K, Thomson LE, Shufelt C, Merz CN. Diastolic dysfunction: improved understanding using emerging imaging techniques. Am Heart J. 2010 Sep; 160(3):394-404. PMID: 20826245.
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Biner S, Rafique A, Rafii F, Tolstrup K, Noorani O, Shiota T, Gurudevan S, Siegel RJ. Reproducibility of proximal isovelocity surface area, vena contracta, and regurgitant jet area for assessment of mitral regurgitation severity. JACC Cardiovasc Imaging. 2010 Mar; 3(3):235-43. PMID: 20223419.
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Rafique AM, Biner S, Ray I, Forrester JS, Tolstrup K, Siegel RJ. Meta-analysis of prognostic value of stress testing in patients with asymptomatic severe aortic stenosis. Am J Cardiol. 2009 Oct 01; 104(7):972-7. PMID: 19766766.
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Biner S, Rafique AM, Ray I, Cuk O, Siegel RJ, Tolstrup K. Aortopathy is prevalent in relatives of bicuspid aortic valve patients. J Am Coll Cardiol. 2009 Jun 16; 53(24):2288-95. PMID: 19520254; PMCID: PMC2761956.
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Biner S, Rafique AM, Wolak A, Tolstrup K, Siegel RJ. Visual assessment of left ventricular dyssynchrony using tissue synchronization imaging. Cardiology. 2009; 114(2):90-9. PMID: 19420936.
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Goland S, Trento A, Czer LS, Eshaghian S, Tolstrup K, Naqvi TZ, De Robertis MA, Mirocha J, Iida K, Siegel RJ. Thoracic aortic arteriosclerosis in patients with degenerative aortic stenosis with and without coexisting coronary artery disease. Ann Thorac Surg. 2008 Jan; 85(1):113-9. PMID: 18154793.
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Atar S, Tolstrup K, Cercek B, Siegel RJ. Chlamydia pneumoniae antibody titers and cardiac calcifications: a cross-sectional serological-echocardiographic correlative study. Isr Med Assoc J. 2007 Jul; 9(7):517-20. PMID: 17710782.
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Goland S, Trento A, Iida K, Czer LS, De Robertis M, Naqvi TZ, Tolstrup K, Akima T, Luo H, Siegel RJ. Assessment of aortic stenosis by three-dimensional echocardiography: an accurate and novel approach. Heart. 2007 Jul; 93(7):801-7. PMID: 17488766; PMCID: PMC1994466.
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Kobal SL, Pollick C, Atar S, Miyamoto T, Aslanian N, Neuman Y, Tolstrup K, Naqvi TZ, Luo H, Macrum B, Siegel RJ. Stress echocardiography in octogenarians: transesophageal atrial pacing is accurate, safe, and well tolerated. J Am Soc Echocardiogr. 2006 Aug; 19(8):1012-6. PMID: 16880096.
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Tolstrup K, Madsen BE, Ruiz JA, Greenwood SD, Camacho J, Siegel RJ, Gertzen HC, Park JW, Smars PA. Non-invasive resting magnetocardiographic imaging for the rapid detection of ischemia in subjects presenting with chest pain. Cardiology. 2006; 106(4):270-6. PMID: 16733351.
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Kobal SL, Trento L, Baharami S, Tolstrup K, Naqvi TZ, Cercek B, Neuman Y, Mirocha J, Kar S, Forrester JS, Siegel RJ. Comparison of effectiveness of hand-carried ultrasound to bedside cardiovascular physical examination. Am J Cardiol. 2005 Oct 01; 96(7):1002-6. PMID: 16188532.
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Neuman Y, Tolstrup K, Blanche C, Luthringer D, Kobal S, Miyamoto T, Luo H, Siegel RJ. Pseudomyxoma originating from the interatrial septum in a heart transplant patient. J Am Soc Echocardiogr. 2005 Jul; 18(7):e1. PMID: 16003277.
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Neuman Y, Cercek B, Aragon J, Lee S, Kobal S, Miyamoto T, Luo H, Tolstrup K, Naqvi TZ, Birnbaum Y, Siegel RJ. Comparison of frequency of left ventricular wall motion abnormalities in patients with a first acute myocardial infarction with versus without left ventricular hypertrophy. Am J Cardiol. 2004 Sep 15; 94(6):763-6. PMID: 15374782.
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Luo H, Chen M, Trento A, Miyamoto T, Kobal SL, Neuman Y, Naqvi TZ, Tolstrup K, Siegel RJ. Usefulness of a hand-carried cardiac ultrasound device for bedside examination of pericardial effusion in patients after cardiac surgery. Am J Cardiol. 2004 Aug 01; 94(3):406-7. PMID: 15276121.
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Kobal SL, Tolstrup K, Luo H, Neuman Y, Miyamoto T, Mirocha J, Naqvi TZ, Siegel RJ. Usefulness of a hand-carried cardiac ultrasound device to detect clinically significant valvular regurgitation in hospitalized patients. Am J Cardiol. 2004 Apr 15; 93(8):1069-72. PMID: 15081463.
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Chen M, Luo H, Miyamoto T, Atar S, Kobal S, Rahban M, Brasch AV, Makkar R, Neuman Y, Naqvi TZ, Tolstrup K, Siegel RJ. Correlation of echo-Doppler aortic valve regurgitation index with angiographic aortic regurgitation severity. Am J Cardiol. 2003 Sep 01; 92(5):634-5. PMID: 12943896.
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Tolstrup K, Roldan CA, Qualls CR, Crawford MH. Aortic valve sclerosis, mitral annular calcium, and aortic root sclerosis as markers of atherosclerosis in men. Am J Cardiol. 2002 May 01; 89(9):1030-4. PMID: 11988190.
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