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Supporting Career Transitions of Senior Faculty: Perspectives of Chairs and Full Professors. J Pediatr. 2024 Jan; 264:113518.
Tolleson-Rinehart S, Rosenthal SL, de Roche AM, Laughon M, Sewell TB, Rivera CM, Gozal D, Hirsch R, Orange JS, Davis SD. PMID: 37244584.
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Regulation of Pulmonary Bacterial Immunity by Follistatin-Like Protein 1. Infect Immun. 2020 Dec 15; 89(1).
Henkel M, Dutta JA, Partyka J, Eddens T, Hirsch R, Kolls JK, Campfield BT. PMID: 33077624; PMCID: PMC7927939.
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The Follistatin-like Protein 1 Pathway Is Important for Maintaining Healthy Articular Cartilage. ACR Open Rheumatol. 2020 Jul; 2(7):407-414.
Chaly Y, Hostager B, Smith S, Hirsch R. PMID: 32530126; PMCID: PMC7368136.
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FSTL-1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema. Am J Respir Crit Care Med. 2020 Apr 15; 201(8):934-945.
Henkel M, Partyka J, Gregory AD, Forno E, Cho MH, Eddens T, Tout AR, Salamacha N, Horne W, Rao KS, Wu Y, Alcorn JF, Kostka D, Hirsch R, Celedón JC, Shapiro SD, Kolls JK, Campfield BT. PMID: 31834999; PMCID: PMC7159415.
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Expanding the Pipeline for Pediatric Physician-Scientists. J Pediatr. 2019 Apr; 207:3-7.e1.
Dermody TS, Hirsch R, Hostetter MK, Orange JS, St Geme JW. PMID: 30922503.
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Follistatin-like protein 1 modulates IL-17 signaling via IL-17RC regulation in stromal cells. Immunol Cell Biol. 2017 Sep; 95(8):656-665.
Campfield BT, Eddens T, Henkel M, Majewski M, Horne W, Chaly Y, Gaffen SL, Hirsch R, Kolls JK. PMID: 28377613; PMCID: PMC5609702.
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Suppression of arthritis-induced bone erosion by a CRAC channel antagonist. RMD Open. 2016; 2(1):e000093.
Blair HC, Soboloff J, Robinson LJ, Tourkova IL, Larrouture QC, Witt MR, Holaskova I, Schafer R, Elliott M, Hirsch R, Barnett JB. PMID: 26819750; PMCID: PMC4716559.
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Follistatin-like protein 1 and its role in inflammation and inflammatory diseases. Immunol Res. 2014 Aug; 59(1-3):266-72.
Chaly Y, Hostager B, Smith S, Hirsch R. PMID: 24838142.
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Follistatin-like protein 1 is a critical mediator of experimental Lyme arthritis and the humoral response to Borrelia burgdorferi infection. Microb Pathog. 2014 Aug; 73:70-9.
Campfield BT, Nolder CL, Marinov A, Bushnell D, Davis A, Spychala C, Hirsch R, Nowalk AJ. PMID: 24768929; PMCID: PMC4899828.
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Follistatin-like protein 1 regulates chondrocyte proliferation and chondrogenic differentiation of mesenchymal stem cells. Ann Rheum Dis. 2015 Jul; 74(7):1467-73.
Chaly Y, Blair HC, Smith SM, Bushnell DS, Marinov AD, Campfield BT, Hirsch R. PMID: 24641944.
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Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1ß secretion from monocytes and macrophages. Eur J Immunol. 2014 May; 44(5):1467-79.
Chaly Y, Fu Y, Marinov A, Hostager B, Yan W, Campfield B, Kellum JA, Bushnell D, Wang Y, Vockley J, Hirsch R. PMID: 24470197; PMCID: PMC4004659.
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Follistatin-like protein 1 and the ferritin/erythrocyte sedimentation rate ratio are potential biomarkers for dysregulated gene expression and macrophage activation syndrome in systemic juvenile idiopathic arthritis. J Rheumatol. 2013 Jul; 40(7):1191-9.
Gorelik M, Fall N, Altaye M, Barnes MG, Thompson SD, Grom AA, Hirsch R. PMID: 23678162; PMCID: PMC3885333.
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20 Fields:
Translation:
Humans
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Do patients with juvenile idiopathic arthritis in clinical remission have evidence of persistent inflammation on 3T magnetic resonance imaging? Arthritis Care Res (Hoboken). 2012 Dec; 64(12):1846-54.
Brown A, Hirsch R, Laor T, Hannon MJ, Levesque MC, Starz T, Francis K, Kwoh CK. PMID: 22740386; PMCID: PMC4398346.
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The DBA/1 strain is a novel mouse model for experimental Borrelia burgdorferi infection. Clin Vaccine Immunol. 2012 Oct; 19(10):1567-73.
Campfield BT, Nolder CL, Davis A, Hirsch R, Nowalk AJ. PMID: 22855391; PMCID: PMC3485876.
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2011 Pediatric Rheumatology Symposium sponsored by the American College of Rheumatology Miami, FL, USA. 2-5 June 2011. Abstracts. Pediatr Rheumatol Online J. 2012 Jul 09; 10 Suppl 1(Suppl 1):A1-A124.
Gorelik M, Wilson D, Shulman S, Hirsch R. PMID: 22817878; PMCID: PMC3402995.
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Plasma follistatin-like protein 1 is elevated in Kawasaki disease and may predict coronary artery aneurysm formation. J Pediatr. 2012 Jul; 161(1):116-9.
Gorelik M, Wilson DC, Cloonan YK, Shulman ST, Hirsch R. PMID: 22316625; PMCID: PMC3349793.
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FSTL1 promotes arthritis in mice by enhancing inflammatory cytokine/chemokine expression. Arthritis Rheum. 2012 Apr; 64(4):1082-8.
Chaly Y, Marinov AD, Oxburgh L, Bushnell DS, Hirsch R. PMID: 22006268; PMCID: PMC3276726.
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Akt fine-tunes NF-?B-dependent gene expression during T cell activation. J Biol Chem. 2011 Oct 14; 286(41):36076-36085.
Cheng J, Phong B, Wilson DC, Hirsch R, Kane LP. PMID: 21862580; PMCID: PMC3195567.
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Hypocomplementemia associated with macrophage activation syndrome in systemic juvenile idiopathic arthritis and adult onset still's disease: 3 cases. J Rheumatol. 2011 Feb; 38(2):396-7.
Gorelik M, Torok KS, Kietz DA, Hirsch R. PMID: 21285182; PMCID: PMC3672253.
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Follistatin-like protein 1 is a mesenchyme-derived inflammatory protein and may represent a biomarker for systemic-onset juvenile rheumatoid arthritis. Arthritis Rheum. 2010 Aug; 62(8):2510-6.
Wilson DC, Marinov AD, Blair HC, Bushnell DS, Thompson SD, Chaly Y, Hirsch R. PMID: 20506332; PMCID: PMC2921021.
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37 Fields:
Translation:
HumansAnimalsCells
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Synovial fluid proteins differentiate between the subtypes of juvenile idiopathic arthritis. Arthritis Rheum. 2010 Jun; 62(6):1813-23.
Rosenkranz ME, Wilson DC, Marinov AD, Decewicz A, Grof-Tisza P, Kirchner D, Giles B, Reynolds PR, Liebman MN, Kolli VS, Thompson SD, Hirsch R. PMID: 20222116; PMCID: PMC2918379.
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6 Fields:
Translation:
Humans
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Pediatric pigmented villonodular synovitis mimicking a septic hip. J Clin Rheumatol. 2010 Mar; 16(2):71-3.
Patel AM, Brown AG, Galambos C, Hirsch R. PMID: 20216127; PMCID: PMC3947543.
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Loeys-Dietz syndrome in pregnancy: a case description and report of a novel mutation. Fetal Diagn Ther. 2009; 26(1):35-7.
Gutman G, Baris HN, Hirsch R, Mandel D, Yaron Y, Lessing JB, Kuperminc MJ. PMID: 19816028.
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Follistatin-like protein 1 promotes arthritis by up-regulating IFN-gamma. J Immunol. 2009 Jan 01; 182(1):234-9.
Clutter SD, Wilson DC, Marinov AD, Hirsch R. PMID: 19109154; PMCID: PMC3150499.
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Is long-term etanercept therapy safe and effective in patients with juvenile RA? Nat Clin Pract Rheumatol. 2008 Dec; 4(12):628-9.
Hirsch R. PMID: 18852716.
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Three-dimensional and thermal surface imaging produces reliable measures of joint shape and temperature: a potential tool for quantifying arthritis. Arthritis Res Ther. 2008; 10(1):R10.
Spalding SJ, Kwoh CK, Boudreau R, Enama J, Lunich J, Huber D, Denes L, Hirsch R. PMID: 18215307; PMCID: PMC2374475.
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Gene therapy for arthritis. Mod Rheumatol. 2008; 18(1):2-14.
Traister RS, Hirsch R. PMID: 18176779; PMCID: PMC2275302.
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Staphylococcus aureus panniculitis complicating juvenile dermatomyositis. Pediatrics. 2007 Feb; 119(2):e528-30.
Spalding SJ, Meza MP, Ranganathan S, Hirsch R. PMID: 17261618.
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Follistatin-like protein-1 is a novel proinflammatory molecule. J Immunol. 2006 Oct 01; 177(7):4758-62.
Miyamae T, Marinov AD, Sowders D, Wilson DC, Devlin J, Boudreau R, Robbins P, Hirsch R. PMID: 16982916.
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Inflammatory cytokine regulation of transgene expression in human fibroblast-like synoviocytes infected with adeno-associated virus. Arthritis Rheum. 2006 Jul; 54(7):2119-26.
Traister RS, Fabre S, Wang Z, Xiao X, Hirsch R. PMID: 16802345.
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NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis. J Exp Med. 2006 May 15; 203(5):1209-19.
Irie J, Wu Y, Wicker LS, Rainbow D, Nalesnik MA, Hirsch R, Peterson LB, Leung PS, Cheng C, Mackay IR, Gershwin ME, Ridgway WM. PMID: 16636131; PMCID: PMC2121204.
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73 Fields:
Translation:
HumansAnimalsCells
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A soluble divalent class I MHC/IgG1 fusion protein activates CD8+ T cells in vivo. Clin Immunol. 2005 Jul; 116(1):65-76.
Carey B, DeLay M, Strasser JE, Chalk C, Dudley-McClain K, Milligan GN, Brunner HI, Thornton S, Hirsch R. PMID: 15925833.
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Serum protein profile in systemic-onset juvenile idiopathic arthritis differentiates response versus nonresponse to therapy. Arthritis Res Ther. 2005; 7(4):R746-55.
Miyamae T, Malehorn DE, Lemster B, Mori M, Imagawa T, Yokota S, Bigbee WL, Welsh M, Klarskov K, Nishomoto N, Vallejo AN, Hirsch R. PMID: 15987476; PMCID: PMC1175022.
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Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo. Mol Ther. 2005 Apr; 11(4):600-7.
Jennings K, Miyamae T, Traister R, Marinov A, Katakura S, Sowders D, Trapnell B, Wilson JM, Gao G, Hirsch R. PMID: 15771962.
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Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy. Mod Rheumatol. 2004; 14(1):18-24.
Katakura S, Jennings K, Watanabe S, Adachi E, Thornton S, Gao GP, Wilson JM, Burstein H, Trapnell B, Hirsch R. PMID: 17028800.
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DNA microarray analysis reveals novel gene expression profiles in collagen-induced arthritis. Clin Immunol. 2002 Nov; 105(2):155-68.
Thornton S, Sowders D, Aronow B, Witte DP, Brunner HI, Giannini EH, Hirsch R. PMID: 12482389.
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Gene transfer of a fibronectin peptide inhibits leukocyte recruitment and suppresses inflammation in mouse collagen-induced arthritis. Arthritis Rheum. 2002 Apr; 46(4):1102-8.
Imagawa T, Watanabe S, Katakura S, Boivin GP, Hirsch R. PMID: 11953990.
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A single-chain class II MHC-IgG3 fusion protein inhibits autoimmune arthritis by induction of antigen-specific hyporesponsiveness. J Immunol. 2002 Mar 01; 168(5):2554-9.
Zuo L, Cullen CM, DeLay ML, Thornton S, Myers LK, Rosloniec EF, Boivin GP, Hirsch R. PMID: 11859151.
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