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Prototypical Recombinant Multi-Protease-Inhibitor-Resistant Infectious Molecular Clones of Human Immunodeficiency Virus Type 1. Antimicrob Agents Chemother. 2013 Sep; 57(9):4290-4299.
Varghese V, Mitsuya Y, Fessel WJ, Liu TF, Melikian GL, Katzenstein DA, Schiffer CA, Holmes SP, Shafer RW. PMID: 23796938.
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Human immunodeficiency virus type 1 isolates with the reverse transcriptase (RT) mutation Q145M retain nucleoside and nonnucleoside RT inhibitor susceptibility. Antimicrob Agents Chemother. 2009 May; 53(5):2196-8.
Varghese V, Mitsuya Y, Shahriar R, Bachmann MH, Fessel WJ, Kagan RM, Shafer RW. PMID: 19223644.
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HumansCells
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Minority human immunodeficiency virus type 1 variants in antiretroviral-naive persons with reverse transcriptase codon 215 revertant mutations. J Virol. 2008 Nov; 82(21):10747-55.
Mitsuya Y, Varghese V, Wang C, Liu TF, Holmes SP, Jayakumar P, Gharizadeh B, Ronaghi M, Klein D, Fessel WJ, Shafer RW. PMID: 18715933.
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47 Fields:
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HumansCells
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Viral population estimation using pyrosequencing. PLoS Comput Biol. 2008 May 09; 4(4):e1000074.
Eriksson N, Pachter L, Mitsuya Y, Rhee SY, Wang C, Gharizadeh B, Ronaghi M, Shafer RW, Beerenwinkel N. PMID: 18437230.
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103 Fields:
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Cells
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Prevalence of darunavir resistance-associated mutations: patterns of occurrence and association with past treatment. J Infect Dis. 2007 Oct 15; 196(8):1177-9.
Mitsuya Y, Liu TF, Rhee SY, Fessel WJ, Shafer RW. PMID: 17955436.
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27 Fields:
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HumansCells
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Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance. Genome Res. 2007 Aug; 17(8):1195-201.
Wang C, Mitsuya Y, Gharizadeh B, Ronaghi M, Shafer RW. PMID: 17600086.
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207 Fields:
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HumansCells
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N88D facilitates the co-occurrence of D30N and L90M and the development of multidrug resistance in HIV type 1 protease following nelfinavir treatment failure. AIDS Res Hum Retroviruses. 2006 Dec; 22(12):1300-5.
Mitsuya Y, Winters MA, Fessel WJ, Rhee SY, Hurley L, Horberg M, Schiffer CA, Zolopa AR, Shafer RW. PMID: 17209774.
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9 Fields:
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HumansCells
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HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL. . 2006 Sep; 43(1):56-9.
Mitsuya Y, Winters MA, Fessel WJ, Rhee SY, Slome S, Flamm J, Horberg M, Hurley L, Klein D, Shafer RW. PMID: 16885777.
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A nitric oxide synthase inhibitor, N(G)-nitro-l-arginine-methyl-ester, exerts potent antiangiogenic effects on plasmacytoma in a newly established multiple myeloma severe combined immunodeficient mouse model. Br J Haematol. 2003 Feb; 120(3):396-404.
Uneda S, Hata H, Matsuno F, Nagasaki A, Harada N, Mitsuya Y, Matsuzaki H, Mitsuya H. PMID: 12580953.
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2 Fields:
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AnimalsCells
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Macrophage inflammatory protein-1 alpha is produced by human multiple myeloma (MM) cells and its expression correlates with bone lesions in patients with MM. Br J Haematol. 2003 Jan; 120(1):53-5.
Uneda S, Hata H, Matsuno F, Harada N, Mitsuya Y, Kawano F, Mitsuya H. PMID: 12492576.
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19 Fields:
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HumansCells