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Yutaka Hashimoto

Title(s)Visitor, Campus Life Services
SchoolChancellor/EVC/FAS
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    Collapse Biography 
    Collapse education and training
    Tokyo University of Pharmacology & Life Science, JapanPharmD03/2006Gastrointestinal Cancer
    Tokyo Medical & Dental Univ., JapanPhD03/2011Gastrointestinal Cancer
    Tokyo Medical & Dental Univ., JapanPostdoctoral Fellow/JSPS Fellow05/2012Gastrointestinal Cancer
    Bellvitge Biomedical Institute/ Catalonia Cancer Center, SpainJSPS Fellow/ Marie Curie Foundation Fellow05/2015Gastrointestinal Cancer
    UCSF, USAPostdoctoral FellowUrological Cancer

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Temporal and Sex-Dependent N-Glycosylation Dynamics in Rat Serum. Int J Mol Sci. 2025 Jul 27; 26(15). Yagi H, Kondo S, Murakami R, Yogo R, Yanaka S, Umezawa F, Yagi-Utsumi M, Fujita A, Okina M, Hashimoto Y, Hotta Y, Kato Y, Nakajima K, Furukawa JI, Kato K. PMID: 40806398; PMCID: PMC12347175.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Aberrant activation of IL-6/JAK/STAT3/FOSL1 signaling induces renal abnormalities in a Xenopus model of Joubert syndrome-related disorders. J Biol Chem. 2025 Aug; 301(8):110413. Uuganbayar U, Ninomiya H, Shimada IS, Yamada C, Kanie M, Kawai S, Asai T, Miyoshi-Akiyama T, Itoh M, Hashimoto Y, Kato Y. PMID: 40570958; PMCID: PMC12302719.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. The K346T mutant of GnT-III bearing weak in vitro and potent intracellular activity. Biochim Biophys Acta Gen Subj. 2024 09; 1868(9):130663. Hashimoto Y, Kawade H, Bao W, Morii S, Nakano M, Nagae M, Murakami R, Tokoro Y, Nakashima M, Cai Z, Isaji T, Gu J, Nakajima K, Kizuka Y. PMID: 38936637.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Noise pareidolia test for predicting delirium in hospitalized older patients with cognitive decline. Geriatr Gerontol Int. 2022 Oct; 22(10):883-888. Hashimoto Y, Kano O, Ebihara S. PMID: 36071029.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation. Dev Cell. 2021 11 08; 56(21):3019-3034.e7. Shi W, Sheng X, Dorr KM, Hutton JE, Emerson JI, Davies HA, Andrade TD, Wasson LK, Greco TM, Hashimoto Y, Federspiel JD, Robbe ZL, Chen X, Arnold AP, Cristea IM, Conlon FL. PMID: 34655525; PMCID: PMC9290207.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    6. Suppressor effect of catechol-O-methyltransferase gene in prostate cancer. PLoS One. 2021; 16(9):e0253877. Hashimoto Y, Shiina M, Maekawa S, Kato T, Shahryari V, Kulkarni P, Dasgupta P, Yamamura S, Saini S, Tabatabai ZL, Dahiya R, Tanaka Y. PMID: 34587154; PMCID: PMC8480839.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    7. Role of miR-182/PDCD4 axis in aggressive behavior of prostate cancer in the African Americans. BMC Cancer. 2021 Sep 15; 21(1):1028. Shiina M, Hashimoto Y, Kulkarni P, Dasgupta P, Shahryari V, Yamamura S, Tanaka Y, Dahiya R. PMID: 34525952; PMCID: PMC8444584.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    8. A lncRNA TCL6-miR-155 Interaction Regulates the Src-Akt-EMT Network to Mediate Kidney Cancer Progression and Metastasis. Cancer Res. 2021 03 15; 81(6):1500-1512. Kulkarni P, Dasgupta P, Hashimoto Y, Shiina M, Shahryari V, Tabatabai ZL, Yamamura S, Tanaka Y, Saini S, Dahiya R, Majid S. PMID: 33500248; PMCID: PMC7969457.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    9. Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning. Mol Brain. 2020 11 10; 13(1):146. Shirane M, Shoji H, Hashimoto Y, Katagiri H, Kobayashi S, Manabe T, Miyakawa T, Nakayama KI. PMID: 33172474; PMCID: PMC7654181.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    10. Role of the PI3K/Akt pathway in cadmium induced malignant transformation of normal prostate epithelial cells. Toxicol Appl Pharmacol. 2020 12 15; 409:115308. Kulkarni P, Dasgupta P, Bhat NS, Hashimoto Y, Saini S, Shahryari V, Yamamura S, Shiina M, Tanaka Y, Dahiya R, Majid S. PMID: 33129824; PMCID: PMC7726053.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    11. LncRNA CDKN2B-AS1/miR-141/cyclin D network regulates tumor progression and metastasis of renal cell carcinoma. Cell Death Dis. 2020 08 19; 11(8):660. Dasgupta P, Kulkarni P, Majid S, Hashimoto Y, Shiina M, Shahryari V, Bhat NS, Tabatabai L, Yamamura S, Saini S, Tanaka Y, Dahiya R. PMID: 32814766; PMCID: PMC7438482.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    12. Activation of the Erk/MAPK signaling pathway is a driver for cadmium induced prostate cancer. Toxicol Appl Pharmacol. 2020 08 15; 401:115102. Dasgupta P, Kulkarni P, Bhat NS, Majid S, Shiina M, Shahryari V, Yamamura S, Tanaka Y, Gupta RK, Dahiya R, Hashimoto Y. PMID: 32512071; PMCID: PMC7425797.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    13. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020 02 10; 11(1):806. Hashimoto Y, Sheng X, Murray-Nerger LA, Cristea IM. PMID: 32041945; PMCID: PMC7010728.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    14. Genistein Represses HOTAIR/Chromatin Remodeling Pathways to Suppress Kidney Cancer. Cell Physiol Biochem. 2020 01 22; 54(1):53-70. Imai-Sumida M, Dasgupta P, Kulkarni P, Shiina M, Hashimoto Y, Shahryari V, Majid S, Tanaka Y, Dahiya R, Yamamura S. PMID: 31961100; PMCID: PMC7382546.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    15. Upregulation of miR-130b Contributes to Risk of Poor Prognosis and Racial Disparity in African-American Prostate Cancer. Cancer Prev Res (Phila). 2019 09; 12(9):585-598. Hashimoto Y, Shiina M, Dasgupta P, Kulkarni P, Kato T, Wong RK, Tanaka Y, Shahryari V, Maekawa S, Yamamura S, Saini S, Deng G, Tabatabai ZL, Majid S, Dahiya R. PMID: 31266828; PMCID: PMC7327781.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    16. Influence of lifestyle choices on risks of CYP1B1 polymorphisms for prostate cancer. J Cell Mol Med. 2018 10; 22(10):4676-4687. Kato T, Hashimoto Y, Wong RK, Mitsui Y, Maekawa S, Chang I, Shahryari V, Yamamura S, Majid S, Saini S, Tabatabai ZL, Dahiya R, Deguchi T, Tanaka Y. PMID: 30133114; PMCID: PMC6156244.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    17. Elevated miR-182-5p Associates with Renal Cancer Cell Mitotic Arrest through Diminished MALAT-1 Expression. Mol Cancer Res. 2018 11; 16(11):1750-1760. Kulkarni P, Dasgupta P, Bhat NS, Shahryari V, Shiina M, Hashimoto Y, Majid S, Deng G, Saini S, Tabatabai ZL, Yamamura S, Tanaka Y, Dahiya R. PMID: 30037856; PMCID: PMC6214767.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    18. MicroRNA-203 Inhibits Long Noncoding RNA HOTAIR and Regulates Tumorigenesis through Epithelial-to-mesenchymal Transition Pathway in Renal Cell Carcinoma. Mol Cancer Ther. 2018 05; 17(5):1061-1069. Dasgupta P, Kulkarni P, Majid S, Shahryari V, Hashimoto Y, Bhat NS, Shiina M, Deng G, Saini S, Tabatabai ZL, Yamamura S, Tanaka Y, Dahiya R. PMID: 29440295; PMCID: PMC5932222.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    19. Enhancement of transdermal protein delivery by photothermal effect of gold nanorods coated on polysaccharide-based hydrogel. Eur J Pharm Biopharm. 2017 Oct; 119:91-95. Haine AT, Koga Y, Hashimoto Y, Higashi T, Motoyama K, Arima H, Niidome T. PMID: 28600224.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    20. A novel microRNA regulator of prostate cancer epithelial-mesenchymal transition. Cell Death Differ. 2017 07; 24(7):1263-1274. Bucay N, Bhagirath D, Sekhon K, Yang T, Fukuhara S, Majid S, Shahryari V, Tabatabai Z, Greene KL, Hashimoto Y, Shiina M, Yamamura S, Tanaka Y, Deng G, Dahiya R, Saini S. PMID: 28498363; PMCID: PMC5520174.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    21. The role of miR-24 as a race related genetic factor in prostate cancer. Oncotarget. 2017 Mar 07; 8(10):16581-16593. Hashimoto Y, Shiina M, Kato T, Yamamura S, Tanaka Y, Majid S, Saini S, Shahryari V, Kulkarni P, Dasgupta P, Mitsui Y, Sumida M, Deng G, Tabatabai L, Kumar D, Dahiya R. PMID: 28157714; PMCID: PMC5369986.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    22. Versican Promotes Tumor Progression, Metastasis and Predicts Poor Prognosis in Renal Carcinoma. Mol Cancer Res. 2017 07; 15(7):884-895. Mitsui Y, Shiina H, Kato T, Maekawa S, Hashimoto Y, Shiina M, Imai-Sumida M, Kulkarni P, Dasgupta P, Wong RK, Hiraki M, Arichi N, Fukuhara S, Yamamura S, Majid S, Saini S, Deng G, Dahiya R, Nakajima K, Tanaka Y. PMID: 28242813; PMCID: PMC5890926.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    23. Differential expression of miR-34b and androgen receptor pathway regulate prostate cancer aggressiveness between African-Americans and Caucasians. Oncotarget. 2017 Jan 31; 8(5):8356-8368. Shiina M, Hashimoto Y, Kato T, Yamamura S, Tanaka Y, Majid S, Saini S, Varahram S, Kulkarni P, Dasgupta P, Mitsui Y, Sumida M, Tabatabai L, Deng G, Kumar D, Dahiya R. PMID: 28039468; PMCID: PMC5352406.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    24. Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):E7535-E7544. Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, Galán M, Sala N, Akiyama Y, Martínez-Iniesta M, Farré L, Villanueva A, Gross M, Diederichs S, Guil S, Esteller M. PMID: 27821766; PMCID: PMC5127373.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    25. Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer. Oncotarget. 2016 Oct 18; 7(42):68371-68384. Nip H, Dar AA, Saini S, Colden M, Varahram S, Chowdhary H, Yamamura S, Mitsui Y, Tanaka Y, Kato T, Hashimoto Y, Shiina M, Kulkarni P, Dasgupta P, Imai-Sumida M, Tabatabai ZL, Greene K, Deng G, Dahiya R, Majid S. PMID: 27634912; PMCID: PMC5356562.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    26. Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer. Oncotarget. 2016 Aug 02; 7(31):49107-49121. Mitsui Y, Chang I, Kato T, Hashimoto Y, Yamamura S, Fukuhara S, Wong DK, Shiina M, Imai-Sumida M, Majid S, Saini S, Shiina H, Nakajima K, Deng G, Dahiya R, Tanaka Y. PMID: 27203547; PMCID: PMC5226494.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    27. DNA methylation patterns as noninvasive biomarkers and targets of epigenetic therapies in colorectal cancer. Epigenomics. 2016 05; 8(5):685-703. Hashimoto Y, Zumwalt TJ, Goel A. PMID: 27102979; PMCID: PMC4928499.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    28. A comprehensive DNA methylation profile of epithelial-to-mesenchymal transition. Cancer Res. 2014 Oct 01; 74(19):5608-19. Carmona FJ, Davalos V, Vidal E, Gomez A, Heyn H, Hashimoto Y, Vizoso M, Martinez-Cardus A, Sayols S, Ferreira HJ, Sánchez-Mut JV, Morán S, Margelí M, Castella E, Berdasco M, Stefansson OA, Eyfjord JE, Gonzalez-Suarez E, Dopazo J, Orozco M, Gut IG, Esteller M. PMID: 25106427.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    29. MiR-9 downregulates CDX2 expression in gastric cancer cells. Int J Cancer. 2011 Dec 01; 129(11):2611-20. Rotkrua P, Akiyama Y, Hashimoto Y, Otsubo T, Yuasa Y. PMID: 21225631.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    30. MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis. PLoS One. 2011 Jan 27; 6(1):e16617. Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K, Yuasa Y. PMID: 21304604; PMCID: PMC3029394.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    31. miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer. Int J Cancer. 2010 Sep 01; 127(5):1106-14. Wada R, Akiyama Y, Hashimoto Y, Fukamachi H, Yuasa Y. PMID: 20020497.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    32. Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis. Carcinogenesis. 2010 May; 31(5):777-84. Hashimoto Y, Akiyama Y, Otsubo T, Shimada S, Yuasa Y. PMID: 20080834.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    33. DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients. Int J Cancer. 2009 Jun 01; 124(11):2677-82. Yuasa Y, Nagasaki H, Akiyama Y, Hashimoto Y, Takizawa T, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K. PMID: 19170207.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
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