Allison Williams, PhD

Title(s)Assistant Professor, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Address600 16th St, #S572B
San Francisco CA 94158
ORCID ORCID Icon0000-0002-0726-141X Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    Institut Pasteur2013Pasteur Maladies Infectieuses fellowship
    Institut Pasteur2010  - 2013EMBO Long Term Fellowship
    St. Jude Children’s Research Hospital2007  - 2010 The Hartwell Foundation Individual Biomedical Post-Doctoral Award

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease. Nat Commun. 2023 Dec 06; 14(1):8072. Tejada-Arranz A, Lulla A, Bouilloux-Lafont M, Turlin E, Pei XY, Douché T, Matondo M, Williams AH, Raynal B, Luisi BF, De Reuse H. PMID: 38057323; PMCID: PMC10700544.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. The mechanistic landscape of Lytic transglycosylase as targets for antibacterial therapy. Curr Opin Struct Biol. 2022 Oct 27; 77:102480. Martinez-Bond EA, Soriano BM, Williams AH. PMID: 36323133.
      View in: PubMed   Mentions: 2     Fields:    
    3. eLife Digest. Defective enzyme weakens cell wall. 2020. Allison Hillary Williams et al. . View Publication.
    4. Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis. Elife. 2020 02 05; 9. Williams AH, Wheeler R, Deghmane AE, Santecchia I, Schaub RE, Hicham S, Moya Nilges M, Malosse C, Chamot-Rooke J, Haouz A, Dillard JP, Robins WP, Taha MK, Gomperts Boneca I. PMID: 32022687; PMCID: PMC7083599.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    5. The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation. Nat Commun. 2019 07 08; 10(1):3005. Williams AH, Redzej A, Rolhion N, Costa TRD, Rifflet A, Waksman G, Cossart P. PMID: 31285450; PMCID: PMC6614362.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    6. Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase. Sci Rep. 2019 03 08; 9(1):3947. Dangkulwanich M, Raetz CRH, Williams AH. PMID: 30850651; PMCID: PMC6408518.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    7. Author Correction: N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes. Nat Microbiol. 2018 Aug; 3(8):962. Impens F, Rolhion N, Radoshevich L, Bécavin C, Duval M, Mellin J, García Del Portillo F, Pucciarelli MG, Williams AH, Cossart P. PMID: 29941881; PMCID: PMC7028393.
      View in: PubMed   Mentions:    Fields:    
    8. A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. J Biol Chem. 2018 04 20; 293(16):6000-6010. Williams AH, Wheeler R, Rateau L, Malosse C, Chamot-Rooke J, Haouz A, Taha MK, Boneca IG. PMID: 29483188; PMCID: PMC5912472.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    9. Bulgecin A: The Key to a Broad-Spectrum Inhibitor  That Targets Lytic Transglycosylases. Antibiotics (Basel). 2017 Feb 22; 6(1). Williams AH, Wheeler R, Thiriau C, Haouz A, Taha MK, Boneca IG. PMID: 28241458; PMCID: PMC5372988.
      View in: PubMed   Mentions: 16  
    10. N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes. Nat Microbiol. 2017 Feb 13; 2:17005. Impens F, Rolhion N, Radoshevich L, Bécavin C, Duval M, Mellin J, García Del Portillo F, Pucciarelli MG, Williams AH, Cossart P. PMID: 28191904; PMCID: PMC5802382.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    11. Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members. Acta Crystallogr D Biol Crystallogr. 2014 Oct; 70(Pt 10):2631-9. Williams AH, Veyrier FJ, Bonis M, Michaud Y, Raynal B, Taha MK, White SW, Haouz A, Boneca IG. PMID: 25286847; PMCID: PMC4188005.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    12. The dynamics of peptidoglycan structure and function: conference report on the 3rd Great Wall Symposium. Res Microbiol. 2014 Jan; 165(1):60-7. Williams AH, Boneca IG, Burrows LL, Bugg TD. PMID: 24239960.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    13. De-O-acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis. Mol Microbiol. 2013 Mar; 87(5):1100-12. Veyrier FJ, Williams AH, Mesnage S, Schmitt C, Taha MK, Boneca IG. PMID: 23373517.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    14. Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. Mol Cell. 2011 Nov 04; 44(3):451-61. Taherbhoy AM, Tait SW, Kaiser SE, Williams AH, Deng A, Nourse A, Hammel M, Kurinov I, Rock CO, Green DR, Schulman BA. PMID: 22055190; PMCID: PMC3277881.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    15. Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA. Biochemistry. 2009 Jul 07; 48(26):6191-201. Robins LI, Williams AH, Raetz CR. PMID: 19456129; PMCID: PMC2710806.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    16. Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase. Proc Natl Acad Sci U S A. 2007 Aug 21; 104(34):13543-50. Williams AH, Raetz CR. PMID: 17698807; PMCID: PMC1959417.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    17. Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide. Proc Natl Acad Sci U S A. 2006 Jul 18; 103(29):10877-82. Williams AH, Immormino RM, Gewirth DT, Raetz CR. PMID: 16835299; PMCID: PMC1544142.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    18. Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3"-hydroxyl group. J Biol Chem. 2004 Jun 11; 279(24):25411-9. Sweet CR, Williams AH, Karbarz MJ, Werts C, Kalb SR, Cotter RJ, Raetz CR. PMID: 15044493; PMCID: PMC2597548.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells