Andrew Capacci, PhD

Title(s)Associate Professor, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #442
San Francisco CA 94158
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    1. Elucidation of the GSK3α Structure Informs the Design of Novel, Paralog-Selective Inhibitors. ACS Chem Neurosci. 2023 03 15; 14(6):1080-1094. Amaral B, Capacci A, Anderson T, Tezer C, Bajrami B, Lulla M, Lucas B, Chodaparambil JV, Marcotte D, Kumar PR, Murugan P, Spilker K, Cullivan M, Wang T, Peterson AC, Enyedy I, Ma B, Chen T, Yousaf Z, Calhoun M, Golonzhka O, Dillon GM, Koirala S. PMID: 36812145; PMCID: PMC10020971.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators. Bioorg Med Chem Lett. 2020 02 15; 30(4):126852. Ma B, Lucas B, Capacci A, Lin EY, Jones JH, Dechantsreiter M, Enyedy I, Marcotte D, Xiao G, Li B, Richter K. PMID: 31898999.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    3. CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling. Sci Signal. 2018 07 31; 11(541). Henry KL, Kellner D, Bajrami B, Anderson JE, Beyna M, Bhisetti G, Cameron T, Capacci AG, Bertolotti-Ciarlet A, Feng J, Gao B, Hopkins B, Jenkins T, Li K, May-Dracka T, Murugan P, Wei R, Zeng W, Allaire N, Buckler A, Loh C, Juhasz P, Lucas B, Ennis KA, Vollman E, Cahir-McFarland E, Hett EC, Ols ML. PMID: 30065029.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    4. Direct, enantioselective α-alkylation of aldehydes using simple olefins. Nat Chem. 2017 11; 9(11):1073-1077. Capacci AG, Malinowski JT, McAlpine NJ, Kuhne J, MacMillan DWC. PMID: 29064486; PMCID: PMC5665178.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    5. Efficient chiral monophosphorus ligands for asymmetric Suzuki-Miyaura coupling reactions. Org Lett. 2012 May 04; 14(9):2258-61. Tang W, Patel ND, Xu G, Xu X, Savoie J, Ma S, Hao MH, Keshipeddy S, Capacci AG, Wei X, Zhang Y, Gao JJ, Li W, Rodriguez S, Lu BZ, Yee NK, Senanayake CH. PMID: 22497425.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    6. Diastereoselective intramolecular Friedel-Crafts alkylation of tetralins. Org Lett. 2011 Jun 17; 13(12):3000-3. Liébert C, Brinks MK, Capacci AG, Fleming MJ, Lautens M. PMID: 21591612.
      View in: PubMed   Mentions: 1     Fields:    
    7. A general and special catalyst for Suzuki-Miyaura coupling processes. Angew Chem Int Ed Engl. 2010 Aug 09; 49(34):5879-83. Tang W, Capacci AG, Wei X, Li W, White A, Patel ND, Savoie J, Gao JJ, Rodriguez S, Qu B, Haddad N, Lu BZ, Krishnamurthy D, Yee NK, Senanayake CH. PMID: 20632427.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    8. Copper catalyzed asymmetric propargylation of aldehydes. J Am Chem Soc. 2010 Jun 09; 132(22):7600-1. Fandrick DR, Fandrick KR, Reeves JT, Tan Z, Tang W, Capacci AG, Rodriguez S, Song JJ, Lee H, Yee NK, Senanayake CH. PMID: 20481453.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    9. Novel and efficient chiral bisphosphorus ligands for rhodium-catalyzed asymmetric hydrogenation. Org Lett. 2010 Mar 05; 12(5):1104-7. Tang W, Capacci AG, White A, Ma S, Rodriguez S, Qu B, Savoie J, Patel ND, Wei X, Haddad N, Grinberg N, Yee NK, Krishnamurthy D, Senanayake CH. PMID: 20148522.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    10. Novel, tunable, and efficient chiral bisdihydrobenzooxaphosphole ligands for asymmetric hydrogenation. Org Lett. 2010 Jan 01; 12(1):176-9. Tang W, Qu B, Capacci AG, Rodriguez S, Wei X, Haddad N, Narayanan B, Ma S, Grinberg N, Yee NK, Krishnamurthy D, Senanayake CH. PMID: 19950894.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    11. A facile and practical synthesis of N-acetyl enamides. J Org Chem. 2009 Dec 18; 74(24):9528-30. Tang W, Capacci A, Sarvestani M, Wei X, Yee NK, Senanayake CH. PMID: 19921804.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
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