Christopher Hernandez, PhD
Biography
| Stanford University, Stanford, CA | PhD | 2001 | Mechanical Engineering |
| Stanford University, Stanford, CA | MS | 1997 | Mechanical Engineering |
| Harvard University, Cambridge, MA | SB | 1996 | Engineering Sciences (Biomedical Engineering) |
Overview
I am a mechanical engineer and bioengineer. My laboratory studies interactions between microbes, musculoskeletal tissues and materials. We are currently studying the effects of the gut microbiome on the musculoskeletal system and the success of orthopaedic surgery. Additionally we are studying mechanobiology of bacteria and advancing the new field of Engineered Living Materials.
Research
Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Microbiome-induced increases and decreases in bone matrix strength can be initiated after skeletal maturity. J Bone Miner Res. 2024 Oct 29; 39(11):1621-1632.
Liu C, Cyphert EL, Stephen SJ, Wang B, Morales AL, Nixon JC, Natsoulas NR, Garcia M, Carmona PB, Vill AC, Donnelly E, Brito IL, Vashishth D, Hernandez CJ. PMID: 39348436; PMCID: PMC11523134.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Determining the Young's Modulus of the Bacterial Cell Envelope. ACS Biomater Sci Eng. 2024 05 13; 10(5):2956-2966.
Lee J, Jha K, Harper CE, Zhang W, Ramsukh M, Bouklas N, Dörr T, Chen P, Hernandez CJ. PMID: 38593061.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Make engineered living materials carry their weight. 2023; 6(11):3705-3718.
Heveran, C.M.
Hernandez, C.J. View Publication.
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Mechanical stimuli activate gene expression via a cell envelope stress sensing pathway. Sci Rep. 2023 08 26; 13(1):13979.
Harper CE, Zhang W, Lee J, Shin JH, Keller MR, van Wijngaarden E, Chou E, Wang Z, Dörr T, Chen P, Hernandez CJ. PMID: 37633922; PMCID: PMC10460444.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Mechanical stress compromises multicomponent efflux complexes in bacteria. Proc Natl Acad Sci U S A. 2019 12 17; 116(51):25462-25467.
Genova LA, Roberts MF, Wong YC, Harper CE, Santiago AG, Fu B, Srivastava A, Jung W, Wang LM, Krzeminski L, Mao X, Sun X, Hui CY, Chen P, Hernandez CJ. PMID: 31772020; PMCID: PMC6925999.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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Bone-inspired microarchitectures achieve enhanced fatigue life. Proc Natl Acad Sci U S A. 2019 12 03; 116(49):24457-24462.
Torres AM, Trikanad AA, Aubin CA, Lambers FM, Luna M, Rimnac CM, Zavattieri P, Hernandez CJ. PMID: 31740616; PMCID: PMC6900498.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Disruption of the Gut Microbiome Increases the Risk of Periprosthetic Joint Infection in Mice. Clin Orthop Relat Res. 2019 Nov; 477(11):2588-2598.
Hernandez CJ, Yang X, Ji G, Niu Y, Sethuraman AS, Koressel J, Shirley M, Fields MW, Chyou S, Li TM, Luna M, Callahan RL, Ross FP, Lu TT, Brito IL, Carli AV, Bostrom MPG. PMID: 31283731; PMCID: PMC6903863.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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The effects of metabolic syndrome, obesity, and the gut microbiome on load-induced osteoarthritis. Osteoarthritis Cartilage. 2019 Jan; 27(1):129-139.
Guss JD, Ziemian SN, Luna M, Sandoval TN, Holyoak DT, Guisado GG, Roubert S, Callahan RL, Brito IL, van der Meulen MCH, Goldring SR, Hernandez CJ. PMID: 30240938; PMCID: PMC6309743.
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PubMed Mentions:
52 Fields:
Translation:
Animals
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Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties. J Bone Miner Res. 2017 Jun; 32(6):1343-1353.
Guss JD, Horsfield MW, Fontenele FF, Sandoval TN, Luna M, Apoorva F, Lima SF, Bicalho RC, Singh A, Ley RE, van der Meulen MC, Goldring SR, Hernandez CJ. PMID: 28244143; PMCID: PMC5466506.
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PubMed Mentions:
104 Fields:
Translation:
Animals
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Links Between the Microbiome and Bone. J Bone Miner Res. 2016 09; 31(9):1638-46.
Hernandez CJ, Guss JD, Luna M, Goldring SR. PMID: 27317164; PMCID: PMC5434873.
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PubMed Mentions:
109 Fields:
Translation:
HumansAnimals
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Material heterogeneity in cancellous bone promotes deformation recovery after mechanical failure. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):2892-7.
Torres AM, Matheny JB, Keaveny TM, Taylor D, Rimnac CM, Hernandez CJ. PMID: 26929343; PMCID: PMC4801312.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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| Year | Publications |
|---|
| 2016 | 2 |
| 2017 | 1 |
| 2018 | 1 |
| 2019 | 3 |
| 2023 | 2 |
| 2024 | 2 |
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
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