Christopher Hernandez, PhD

Title(s)Professor, Orthopaedic Surgery
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSE, #1145B
San Francisco CA 94143
Emailchristopher.hernandez@ucsf.edu
PronounsHe/Him/His
ORCID ORCID Icon0000-0002-0712-6533 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Stanford University, Stanford, CAPhD2001Mechanical Engineering
    Stanford University, Stanford, CAMS1997Mechanical Engineering
    Harvard University, Cambridge, MASB1996Engineering Sciences (Biomedical Engineering)

    Collapse Overview 
    Collapse Overview
    I am a mechanical engineer and bioengineer. My laboratory studies interactions between microbes, musculoskeletal tissues and materials. We are currently studying the effects of the gut microbiome on the musculoskeletal system and the success of orthopaedic surgery. Additionally we are studying mechanobiology of bacteria and advancing the new field of Engineered Living Materials.

    Collapse Research 
    Collapse Research Activities and Funding
    The Microbiome and Bone Strength
    NIH R01AG067997May 15, 2021 - Feb 28, 2026
    Role: Principal Investigator
    The Microbiome and Bone Strength
    NIH R56AG067997Sep 30, 2020 - Aug 31, 2021
    Role: Principal Investigator
    The Role of Bone Resorption in Bone Marrow Lesions
    NIH R21AR073454May 1, 2018 - Feb 28, 2021
    Role: Principal Investigator
    The microbiome as a risk factor for periprosthetic joint infection
    NIH R21AR071534Feb 17, 2017 - Jan 31, 2020
    Role: Co-Principal Investigator
    Separating Systemic Inflammation From Obesity in Load-Induced Osteoarthritis
    NIH R21AR068061Mar 1, 2015 - Dec 31, 2017
    Role: Principal Investigator
    Associations between gut microbiota, flagellin production and bone microstructure
    NIH F33AR065348Aug 15, 2013 - Aug 14, 2014
    Role: Principal Investigator
    Acquisition of a Nano Computed Tomography Instrument for shared Cornell Imaging f
    NIH S10OD012287Apr 20, 2013 - Apr 19, 2014
    Role: Principal Investigator
    Biomechanical Effects of Microstructural Flaws in Cancellous Bone
    NIH R01AR057362Mar 1, 2010 - Aug 31, 2015
    Role: Principal Investigator
    Three-Dimensional Dynamic Bone Histomorphometry
    NIH R21AR054448Sep 1, 2007 - Aug 31, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Microbiome-induced Increases and Decreases in Bone Matrix Strength can be Initiated After Skeletal Maturity. J Bone Miner Res. 2024 Sep 30. Liu C, Cyphert EL, Stephen SJ, Wang B, Morales AL, Nixon JC, Natsoulas NR, Garcia M, Carmona PB, Vill AC, Donnelly E, Brito IL, Vashishth D, Hernandez CJ. PMID: 39348436.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Effects of high dose aspartame-based sweetener on the gut microbiota and bone strength in young and aged mice. JBMR Plus. 2024 Aug; 8(8):ziae082. Cyphert EL, Liu C, Morales AL, Nixon JC, Blackford E, Garcia M, Cevallos N, Turnbaugh PJ, Brito IL, Booth SL, Hernandez CJ. PMID: 39011468; PMCID: PMC11247189.
      View in: PubMed   Mentions:
    3. Combinatorial characterization of bacterial taxa-driven differences in the microbiome of oyster reefs. bioRxiv. 2024 May 16. Cyphert EL, Nand S, Franco G, Hajkowski M, Soto L, Lee DM, Ferner M, Zabin C, Blumenthal J, Deck A, Boyer K, Burrus K, Hernandez CJ, Anand A. PMID: 38798377; PMCID: PMC11118425.
      View in: PubMed   Mentions:
    4. Determining the Young's Modulus of the Bacterial Cell Envelope. ACS Biomater Sci Eng. 2024 05 13; 10(5):2956-2966. Lee J, Jha K, Harper CE, Zhang W, Ramsukh M, Bouklas N, Dörr T, Chen P, Hernandez CJ. PMID: 38593061.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. Effects of long-term high dose aspartame on body mass, bone strength, femoral geometry, and microbiota composition in a young and aged cohort of male and female mice. bioRxiv. 2024 Jan 03. Cyphert EL, Liu C, Morales AL, Nixon JC, Blackford E, Garcia M, Cevallos N, Turnbaugh PJ, Brito IL, Booth SL, Hernandez CJ. PMID: 38260245; PMCID: PMC10802297.
      View in: PubMed   Mentions:
    6. The 2023 Orthopaedic Research Society's International Consensus Meeting on musculoskeletal infection: Summary from the host immunity section. J Orthop Res. 2024 03; 42(3):518-530. Schwarz EM, Archer NK, Atkins GJ, Bentley KLM, Botros M, Cassat JE, Chisari E, Coraça-Huber DC, Daiss JL, Gill SR, Goodman SB, Harro J, Hernandez CJ, Ivashkiv LB, Kates SL, Marques CNH, Masters EA, Muthukrishnan G, Owen JR, Raafat D, Saito M, Veis DJ, Xie C. PMID: 38102985; PMCID: PMC10932846.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Mechanical stimuli activate gene expression via a cell envelope stress sensing pathway. Sci Rep. 2023 08 26; 13(1):13979. Harper CE, Zhang W, Lee J, Shin JH, Keller MR, van Wijngaarden E, Chou E, Wang Z, Dörr T, Chen P, Hernandez CJ. PMID: 37633922; PMCID: PMC10460444.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    8. Fragile X Messenger Ribonucleoprotein 1 (FMR1), a novel inhibitor of osteoblast/osteocyte differentiation, regulates bone formation, mass, and strength in young and aged male and female mice. Bone Res. 2023 May 17; 11(1):25. Deosthale P, Balanta-Melo J, Creecy A, Liu C, Marcial A, Morales L, Cridlin J, Robertson S, Okpara C, Sanchez DJ, Ayoubi M, Lugo JN, Hernandez CJ, Wallace JM, Plotkin LI. PMID: 37193680; PMCID: PMC10188597.
      View in: PubMed   Mentions: 1     Fields:    
    9. Suppression of Remodeling and Bone Fragility. J Bone Miner Res. 2023 03; 38(3):370-371. Hernandez CJ. PMID: 36754846; PMCID: PMC10023396.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Multiple Dietary Vitamin K Forms Are Converted to Tissue Menaquinone-4 in Mice. J Nutr. 2022 04 01; 152(4):981-993. Ellis JL, Fu X, Karl JP, Hernandez CJ, Mason JB, DeBose-Boyd RA, Booth SL. PMID: 34550377; PMCID: PMC8971004.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    11. Distributions of Microdamage Are Altered Between Trabecular Rods and Plates in Cancellous Bone From Men With Type 2 Diabetes Mellitus. J Bone Miner Res. 2022 04; 37(4):740-752. Sacher SE, Hunt HB, Lekkala S, Lopez KA, Potts J, Heilbronner AK, Stein EM, Hernandez CJ, Donnelly E. PMID: 35064941; PMCID: PMC9833494.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Animal Models of Bone Marrow Lesions in Osteoarthritis. JBMR Plus. 2022 Mar; 6(3):e10609. Bowen A, Shamritsky D, Santana J, Porter I, Feldman E, Pownder SL, Koff MF, Hayashi K, Hernandez CJ. PMID: 35309864; PMCID: PMC8914161.
      View in: PubMed   Mentions:
    13. In Their Own Words: How Trans Women Acquired HIV Infection. AIDS Behav. 2022 Jun; 26(6):2091-2098. Wilson EC, Hernandez CJ, Arayasirikul S, Scheer S, Trujillo D, Sicro S, Turner CM, McFarland W. PMID: 35031891.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Butyrate Inhibits Osteoclast Activity In Vitro and Regulates Systemic Inflammation and Bone Healing in a Murine Osteotomy Model Compared to Antibiotic-Treated Mice. Mediators Inflamm. 2021; 2021:8817421. Wallimann A, Magrath W, Pugliese B, Stocker N, Westermann P, Heider A, Gehweiler D, Zeiter S, Claesson MJ, Richards RG, Akdis CA, Hernandez CJ, O'Mahony L, Thompson K, Moriarty TF. PMID: 34924815; PMCID: PMC8683197.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    15. Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections In Vivo. ACS Infect Dis. 2021 12 10; 7(12):3125-3160. Cyphert EL, Zhang N, Learn GD, Hernandez CJ, von Recum HA. PMID: 34761915; PMCID: PMC9704321.
      View in: PubMed   Mentions: 9     Fields:    
    16. Improved PrEP Awareness and Use among Trans Women in San Francisco, California. AIDS Behav. 2022 Feb; 26(2):596-603. Wilson EC, Hernandez CJ, Scheer S, Trujillo D, Arayasirikul S, Sicro S, McFarland W. PMID: 34390435; PMCID: PMC8813678.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    17. The microbiome: A heritable contributor to bone morphology? Semin Cell Dev Biol. 2022 03; 123:82-87. Hernandez CJ, Moeller AH. PMID: 34246568; PMCID: PMC8813545.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    18. Impaired Bone Matrix: The Key to Fragility in Type 2 Diabetes? J Clin Endocrinol Metab. 2021 06 16; 106(7):e2825-e2827. Hernandez CJ, Stein EM, Donnelly E. PMID: 33693826; PMCID: PMC8208657.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Components of the Gut Microbiome That Influence Bone Tissue-Level Strength. J Bone Miner Res. 2021 09; 36(9):1823-1834. Luna M, Guss JD, Vasquez-Bolanos LS, Castaneda M, Rojas MV, Strong JM, Alabi DA, Dornevil SD, Nixon JC, Taylor EA, Donnelly E, Fu X, Shea MK, Booth SL, Bicalho R, Hernandez CJ. PMID: 33999456; PMCID: PMC8793322.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    20. Musculoskeletal Microbiology: The Microbiome in Orthopaedic Biomechanics. Curr Opin Biomed Eng. 2021 Sep; 19. Hernandez CJ. PMID: 34151053; PMCID: PMC8211101.
      View in: PubMed   Mentions:
    21. Alterations to the gut microbiome impair bone tissue strength in aged mice. Bone Rep. 2021 Jun; 14:101065. Castaneda M, Smith KM, Nixon JC, Hernandez CJ, Rowan S. PMID: 33937443; PMCID: PMC8079457.
      View in: PubMed   Mentions: 8  
    22. High hepatitis C virus seropositivity, viremia, and associated risk factors among trans women living in San Francisco, California. PLoS One. 2021; 16(3):e0249219. Hernandez CJ, Trujillo D, Sicro S, Meza J, Bella M, Daza E, Torres F, McFarland W, Turner CM, Wilson EC. PMID: 33784365; PMCID: PMC8009419.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    23. Characterization of Ultralow Density Cellular Solids: Lessons from 30 years of Bone Biomechanics Research. Adv Eng Mater. 2021 Jul; 23(7). Sacher S, Hernandez CJ, Donnelly E. PMID: 34456625; PMCID: PMC8389487.
      View in: PubMed   Mentions:
    24. Dietary vitamin K is remodeled by gut microbiota and influences community composition. Gut Microbes. 2021 Jan-Dec; 13(1):1-16. Ellis JL, Karl JP, Oliverio AM, Fu X, Soares JW, Wolfe BE, Hernandez CJ, Mason JB, Booth SL. PMID: 33651646; PMCID: PMC7928036.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    25. Musculoskeletal microbiology: The utility of the microbiome in orthopedics. J Orthop Res. 2021 02; 39(2):251-257. Hernandez CJ. PMID: 33245146; PMCID: PMC7855812.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    26. The Gut Microbiome and Bone Strength. Curr Osteoporos Rep. 2020 12; 18(6):677-683. Castaneda M, Strong JM, Alabi DA, Hernandez CJ. PMID: 33030683; PMCID: PMC7736097.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    27. Obesity and load-induced posttraumatic osteoarthritis in the absence of fracture or surgical trauma. J Orthop Res. 2021 05; 39(5):1007-1016. Luna M, Guss JD, Vasquez-Bolanos LS, Alepuz AJ, Dornevil S, Strong J, Alabi D, Shi Q, Pannellini T, Otero M, Brito IL, van der Meulen MCH, Goldring SR, Hernandez CJ. PMID: 32658313; PMCID: PMC7855296.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    28. The importance of diversity, equity, and inclusion in orthopedic research. J Orthop Res. 2020 08; 38(8):1661-1665. Alliston T, Foucher KC, Frederick B, Hernandez CJ, Iatridis JC, Kozloff KM, Lewis KJ, Liu XS, Mercer DM, Ochia R, Queen RM, Rimnac CM, van der Meulen MCH, Westendorf JJ. PMID: 32267012.
      View in: PubMed   Mentions: 8     Fields:    
    29. Improving Treatment Efficacy of In Situ Forming Implants via Concurrent Delivery of Chemotherapeutic and Chemosensitizer. Sci Rep. 2020 04 20; 10(1):6587. Jeganathan S, Budziszewski E, Hernandez C, Dhingra A, Exner AA. PMID: 32313056; PMCID: PMC7170888.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    30. Reply to Zadpoor: Fatigue mechanisms observed in bone provide insight to microarchitectured materials. Proc Natl Acad Sci U S A. 2020 03 31; 117(13):6986. Hernandez CJ, Zavattieri PD, Trikanad AA, Rimnac CM. PMID: 32127470; PMCID: PMC7132293.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells. Breast Cancer Res. 2019 12 05; 21(1):138. Montano MM, Yeh IJ, Chen Y, Hernandez C, Kiselar JG, de la Fuente M, Lawes AM, Nieman MT, Kiser PD, Jacobberger J, Exner AA, Lawes MC. PMID: 31805991; PMCID: PMC6896798.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    32. Bone-inspired microarchitectures achieve enhanced fatigue life. Proc Natl Acad Sci U S A. 2019 12 03; 116(49):24457-24462. Torres AM, Trikanad AA, Aubin CA, Lambers FM, Luna M, Rimnac CM, Zavattieri P, Hernandez CJ. PMID: 31740616; PMCID: PMC6900498.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    33. Disruption of the Gut Microbiome Increases the Risk of Periprosthetic Joint Infection in Mice. Clin Orthop Relat Res. 2019 Nov; 477(11):2588-2598. Hernandez CJ, Yang X, Ji G, Niu Y, Sethuraman AS, Koressel J, Shirley M, Fields MW, Chyou S, Li TM, Luna M, Callahan RL, Ross FP, Lu TT, Brito IL, Carli AV, Bostrom MPG. PMID: 31283731; PMCID: PMC6903863.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    34. Contrast enhanced ultrasound imaging by nature-inspired ultrastable echogenic nanobubbles. Nanoscale. 2019 Sep 07; 11(33):15647-15658. de Leon A, Perera R, Hernandez C, Cooley M, Jung O, Jeganathan S, Abenojar E, Fishbein G, Sojahrood AJ, Emerson CC, Stewart PL, Kolios MC, Exner AA. PMID: 31408083; PMCID: PMC6716144.
      View in: PubMed   Mentions: 45     Fields:    
    35. The microbial metagenome and bone tissue composition in mice with microbiome-induced reductions in bone strength. Bone. 2019 10; 127:146-154. Guss JD, Taylor E, Rouse Z, Roubert S, Higgins CH, Thomas CJ, Baker SP, Vashishth D, Donnelly E, Shea MK, Booth SL, Bicalho RC, Hernandez CJ. PMID: 31207357; PMCID: PMC6708759.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    36. Altered Tissue Composition, Microarchitecture, and Mechanical Performance in Cancellous Bone From Men With Type 2 Diabetes Mellitus. J Bone Miner Res. 2019 07; 34(7):1191-1206. Hunt HB, Torres AM, Palomino PM, Marty E, Saiyed R, Cohn M, Jo J, Warner S, Sroga GE, King KB, Lane JM, Vashishth D, Hernandez CJ, Donnelly E. PMID: 30866111; PMCID: PMC6650336.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    37. Enhancing Tumor Drug Distribution With Ultrasound-Triggered Nanobubbles. J Pharm Sci. 2019 09; 108(9):3091-3098. Nittayacharn P, Yuan HX, Hernandez C, Bielecki P, Zhou H, Exner AA. PMID: 31095958; PMCID: PMC6708467.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    38. Immunomodulatory nanogels overcome restricted immunity in a murine model of gut microbiome-mediated metabolic syndrome. Sci Adv. 2019 03; 5(3):eaav9788. Mosquera MJ, Kim S, Zhou H, Jing TT, Luna M, Guss JD, Reddy P, Lai K, Leifer CA, Brito IL, Hernandez CJ, Singh A. PMID: 30944865; PMCID: PMC6436937.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    39. Sink or float? Characterization of shell-stabilized bulk nanobubbles using a resonant mass measurement technique. Nanoscale. 2019 Jan 17; 11(3):851-855. Hernandez C, Abenojar EC, Hadley J, de Leon AC, Coyne R, Perera R, Gopalakrishnan R, Basilion JP, Kolios MC, Exner AA. PMID: 30601524; PMCID: PMC6350620.
      View in: PubMed   Mentions: 31     Fields:    
    40. Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). J Med Chem. 2018 08 23; 61(16):7358-7373. Chien HC, Colas C, Finke K, Springer S, Stoner L, Zur AA, Venteicher B, Campbell J, Hall C, Flint A, Augustyn E, Hernandez C, Heeren N, Hansen L, Anthony A, Bauer J, Fotiadis D, Schlessinger A, Giacomini KM, Thomas AA. PMID: 30048132; PMCID: PMC6668346.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    41. Bone marrow lesions in osteoarthritis: What lies beneath. J Orthop Res. 2018 07; 36(7):1818-1825. Alliston T, Hernandez CJ, Findlay DM, Felson DT, Kennedy OD. PMID: 29266428; PMCID: PMC8607515.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    42. Current Options and Emerging Biomaterials for Periprosthetic Joint Infection. Curr Rheumatol Rep. 2018 04 30; 20(6):33. Levack AE, Cyphert EL, Bostrom MP, Hernandez CJ, von Recum HA, Carli AV. PMID: 29713837; PMCID: PMC6321987.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    43. The Microbiome and Bone and Joint Disease. Curr Rheumatol Rep. 2017 Nov 04; 19(12):77. Hernandez CJ. PMID: 29101487; PMCID: PMC5737008.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    44. Cryo-EM Visualization of Lipid and Polymer-Stabilized Perfluorocarbon Gas Nanobubbles - A Step Towards Nanobubble Mediated Drug Delivery. Sci Rep. 2017 10 18; 7(1):13517. Hernandez C, Gulati S, Fioravanti G, Stewart PL, Exner AA. PMID: 29044154; PMCID: PMC5647366.
      View in: PubMed   Mentions: 21     Fields:    
    45. An in vivo model of a mechanically-induced bone marrow lesion. J Biomech. 2017 11 07; 64:258-261. Matheny JB, Goff MG, Pownder SL, Koff MF, Hayashi K, Yang X, Bostrom MPG, van der Meulen MCH, Hernandez CJ. PMID: 29056291; PMCID: PMC5694366.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    46. Ultrasound molecular imaging of ovarian cancer with CA-125 targeted nanobubble contrast agents. Nanomedicine. 2017 Oct; 13(7):2159-2168. Gao Y, Hernandez C, Yuan HX, Lilly J, Kota P, Zhou H, Wu H, Exner AA. PMID: 28603079.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    47. Mechanically induced bone formation is not sensitive to local osteocyte density in rat vertebral cancellous bone. J Orthop Res. 2018 02; 36(2):672-681. Cresswell EN, Nguyen TM, Horsfield MW, Alepuz AJ, Metzger TA, Niebur GL, Hernandez CJ. PMID: 28513889.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    48. Predicting in vivo behavior of injectable, in situ-forming drug-delivery systems. Ther Deliv. 2017 07; 8(7):479-483. Hernandez C, Exner AA. PMID: 28350230; PMCID: PMC10072068.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    49. Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties. J Bone Miner Res. 2017 Jun; 32(6):1343-1353. Guss JD, Horsfield MW, Fontenele FF, Sandoval TN, Luna M, Apoorva F, Lima SF, Bicalho RC, Singh A, Ley RE, van der Meulen MC, Goldring SR, Hernandez CJ. PMID: 28244143; PMCID: PMC5466506.
      View in: PubMed   Mentions: 87     Fields:    Translation:Animals
    50. Romosozumab Treatment Converts Trabecular Rods into Trabecular Plates in Male Cynomolgus Monkeys. Calcif Tissue Int. 2017 07; 101(1):82-91. Matheny JB, Torres AM, Ominsky MS, Hernandez CJ. PMID: 28246926.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    51. Understanding Bone Strength Is Not Enough. J Bone Miner Res. 2017 Jun; 32(6):1157-1162. Hernandez CJ, van der Meulen MC. PMID: 28067411; PMCID: PMC5466476.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    52. Macroporous acrylamide phantoms improve prediction of in vivo performance of in situ forming implants. J Control Release. 2016 12 10; 243:225-231. Hernandez C, Gawlik N, Goss M, Zhou H, Jeganathan S, Gilbert D, Exner AA. PMID: 27742445; PMCID: PMC5191949.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    53. LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates. Bioorg Med Chem Lett. 2016 10 15; 26(20):5000-5006. Zur AA, Chien HC, Augustyn E, Flint A, Heeren N, Finke K, Hernandez C, Hansen L, Miller S, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA. PMID: 27624080; PMCID: PMC5076878.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    54. Improving performance of nanoscale ultrasound contrast agents using N,N-diethylacrylamide stabilization. Nanomedicine. 2017 01; 13(1):59-67. Perera RH, Wu H, Peiris P, Hernandez C, Burke A, Zhang H, Exner AA. PMID: 27565686; PMCID: PMC5237399.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    55. Links Between the Microbiome and Bone. J Bone Miner Res. 2016 09; 31(9):1638-46. Hernandez CJ, Guss JD, Luna M, Goldring SR. PMID: 27317164; PMCID: PMC5434873.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimals
    56. Material heterogeneity in cancellous bone promotes deformation recovery after mechanical failure. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):2892-7. Torres AM, Matheny JB, Keaveny TM, Taylor D, Rimnac CM, Hernandez CJ. PMID: 26929343; PMCID: PMC4801312.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    57. Validation of Ultrasound Elastography Imaging for Nondestructive Characterization of Stiffer Biomaterials. Ann Biomed Eng. 2016 May; 44(5):1515-23. Zhou H, Goss M, Hernandez C, Mansour JM, Exner A. PMID: 26369634; PMCID: PMC4791216.
      View in: PubMed   Mentions: 3     Fields:    
    58. Ultrasound imaging beyond the vasculature with new generation contrast agents. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Jul-Aug; 7(4):593-608. Perera RH, Hernandez C, Zhou H, Kota P, Burke A, Exner AA. PMID: 25580914; PMCID: PMC4478095.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    59. The effects of tensile-compressive loading mode and microarchitecture on microdamage in human vertebral cancellous bone. J Biomech. 2014 Nov 28; 47(15):3605-12. Lambers FM, Bouman AR, Tkachenko EV, Keaveny TM, Hernandez CJ. PMID: 25458150; PMCID: PMC4303531.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    60. A microfluidic platform for profiling biomechanical properties of bacteria. Lab Chip. 2014 Jul 21; 14(14):2491-8. Sun X, Weinlandt WD, Patel H, Wu M, Hernandez CJ. PMID: 24855656; PMCID: PMC4104068.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    61. Microdamage caused by fatigue loading in human cancellous bone: relationship to reductions in bone biomechanical performance. PLoS One. 2013; 8(12):e83662. Lambers FM, Bouman AR, Rimnac CM, Hernandez CJ. PMID: 24386247; PMCID: PMC3875472.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    62. Nanobubble ultrasound contrast agents for enhanced delivery of thermal sensitizer to tumors undergoing radiofrequency ablation. Pharm Res. 2014 Jun; 31(6):1407-17. Perera RH, Solorio L, Wu H, Gangolli M, Silverman E, Hernandez C, Peiris PM, Broome AM, Exner AA. PMID: 23943542; PMCID: PMC3925199.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    63. Biomechanical effects of simulated resorption cavities in cancellous bone across a wide range of bone volume fractions. J Bone Miner Res. 2012 Sep; 27(9):1927-35. Easley SK, Chang MT, Shindich D, Hernandez CJ, Keaveny TM. PMID: 22576976; PMCID: PMC3423528.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    64. Irradiation does not modify mechanical properties of cancellous bone under compression. Clin Orthop Relat Res. 2012 Sep; 470(9):2488-95. Hernandez CJ, Ramsey DS, Dux SJ, Chu EH, Rimnac CM. PMID: 22033873; PMCID: PMC3830084.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    65. Three-dimensional dynamic bone histomorphometry. J Bone Miner Res. 2012 Feb; 27(2):486-95. Slyfield CR, Tkachenko EV, Wilson DL, Hernandez CJ. PMID: 22028195; PMCID: PMC3288521.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    66. Ectopic expression of SOX9 in osteoblasts alters bone mechanical properties. Calcif Tissue Int. 2012 Feb; 90(2):76-89. Liang B, Cotter MM, Chen D, Hernandez CJ, Zhou G. PMID: 22143895; PMCID: PMC3272153.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    67. Human evolution and osteoporosis-related spinal fractures. PLoS One. 2011; 6(10):e26658. Cotter MM, Loomis DA, Simpson SW, Latimer B, Hernandez CJ. PMID: 22028933; PMCID: PMC3197574.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    68. Surface contaminants inhibit osseointegration in a novel murine model. Bone. 2011 Nov; 49(5):923-30. Bonsignore LA, Colbrunn RW, Tatro JM, Messerschmitt PJ, Hernandez CJ, Goldberg VM, Stewart MC, Greenfield EM. PMID: 21801863; PMCID: PMC3200470.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    69. Near-terminal creep damage does not substantially influence fatigue life under physiological loading. J Biomech. 2011 Jul 07; 44(10):1995-8. Stern LC, Brinkman JG, Furmanski J, Rimnac CM, Hernandez CJ. PMID: 21592481; PMCID: PMC3543691.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    70. Trabecular microarchitecture of hominoid thoracic vertebrae. Anat Rec (Hoboken). 2009 Aug; 292(8):1098-106. Cotter MM, Simpson SW, Latimer BM, Hernandez CJ. PMID: 19554642.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    71. Voxel size and measures of individual resorption cavities in three-dimensional images of cancellous bone. Bone. 2009 Sep; 45(3):487-92. Tkachenko EV, Slyfield CR, Tomlinson RE, Daggett JR, Wilson DL, Hernandez CJ. PMID: 19482097; PMCID: PMC2728288.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    72. A biomechanical analysis of the effects of resorption cavities on cancellous bone strength. J Bone Miner Res. 2006 Aug; 21(8):1248-55. Hernandez CJ, Gupta A, Keaveny TM. PMID: 16869723; PMCID: PMC1876766.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    73. Trabecular microfracture and the influence of pyridinium and non-enzymatic glycation-mediated collagen cross-links. Bone. 2005 Dec; 37(6):825-32. Hernandez CJ, Tang SY, Baumbach BM, Hwu PB, Sakkee AN, van der Ham F, DeGroot J, Bank RA, Keaveny TM. PMID: 16140600; PMCID: PMC1876767.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    74. Genetic background influences cortical bone response to ovariectomy. J Bone Miner Res. 2005 Dec; 20(12):2150-8. Li CY, Schaffler MB, Wolde-Semait HT, Hernandez CJ, Jepsen KJ. PMID: 16294268.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
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