David Fox, MD

Title(s)Volunteer Associate Clinical Professor, Psychiatry - Fresno
SchoolSchool of Medicine
Address155 N Fresno Street, #001
Fresno CA 93701
Phone559-499-6580
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    Collapse Research 
    Collapse Research Activities and Funding
    Roles of soluble CD13 and its receptor in angiogenesis, monocyte recruitment, and joint inflammation
    NIH R56AR076384Sep 10, 2020 - Aug 31, 2021
    Role: Principal Investigator
    University of Michigan Clinical Autoimmunity Center of Excellence
    NIH UM1AI144298May 1, 2019 - Apr 30, 2024
    Role: Co-Principal Investigator
    Proinflammatory and Autoantigenic Properties of a Novel Citrullinated Form of IL-6 in Rheumatoid Arthritis
    NIH R21AR072931Mar 1, 2018 - Feb 29, 2020
    Role: Principal Investigator
    University of Michigan Autoimmunity Center of Excellence, Clinical Research Progr
    NIH UM1AI110557May 1, 2014 - Apr 30, 2019
    Role: Principal Investigator
    University of Michigan Rheumatic Diseases Research Core Center
    NIH P30AR048310Sep 28, 2001 - Jul 31, 2011
    Role: Principal Investigator
    Unique Surface Structures on Synovial Cells
    NIH R01AR038477Aug 1, 1986 - Aug 31, 2012
    Role: Principal Investigator
    UNIQUE SURFACE STRUCTURES ON RHEUMATOID SYNOVIAL T CELLS
    NIH R29AR038477Aug 1, 1986 - Jul 31, 1991
    Role: Principal Investigator
    Training of Arthritis Research Scientists
    NIH T32AR007080Jul 1, 1976 - Jun 30, 2023
    Role: Co-Principal Investigator
    ARTHRITIS AND MUSCULOSKELETAL DISEASES CENTER
    NIH P60AR020557Dec 31, 2002
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1. J Clin Invest. 2022 06 01; 132(11). Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. PMID: 35439173; PMCID: PMC9151693.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    2. Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma. JCI Insight. 2022 05 09; 7(9). Vichaikul S, Gurrea-Rubio M, Amin MA, Campbell PL, Wu Q, Mattichak MN, Brodie WD, Palisoc PJ, Ali M, Muraoka S, Ruth JH, Model EN, Rohraff DM, Hervoso JL, Mao-Draayer Y, Fox DA, Khanna D, Sawalha AH, Tsou PS. PMID: 35349485; PMCID: PMC9090238.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    3. Characterization of humoral response to COVID mRNA vaccines in multiple sclerosis patients on disease modifying therapies. Vaccine. 2021 10 01; 39(41):6111-6116. Ali A, Dwyer D, Wu Q, Wang Q, Dowling CA, Fox DA, Khanna D, Poland GA, Mao-Draayer Y. PMID: 34483021; PMCID: PMC8411370.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    4. CD6 is a target for cancer immunotherapy. JCI Insight. 2021 03 08; 6(5). Ruth JH, Gurrea-Rubio M, Athukorala KS, Rasmussen SM, Weber DP, Randon PM, Gedert RJ, Lind ME, Amin MA, Campbell PL, Tsou PS, Mao-Draayer Y, Wu Q, Lanigan TM, Keshamouni VG, Singer NG, Lin F, Fox DA. PMID: 33497367; PMCID: PMC8021120.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    5. Correction to: Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis. Arthritis Res Ther. 2021 Mar 04; 23(1):73. Fox DA, Lundy SK, Whitfield ML, Berrocal V, Campbell P, Rasmussen S, Ohara R, Stinson A, Gurrea-Rubio M, Wiewiora E, Spino C, Bush E, Furst D, Pillai S, Khanna D. PMID: 33663570; PMCID: PMC7931548.
      View in: PubMed   Mentions: 1     Fields:    
    6. Interferon-stimulated GTPases in autoimmune and inflammatory diseases: promising role for the guanylate-binding protein (GBP) family. Rheumatology (Oxford). 2021 02 01; 60(2):494-506. Haque M, Siegel RJ, Fox DA, Ahmed S. PMID: 33159795; PMCID: PMC7850581.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    7. A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF. Nat Commun. 2021 01 25; 12(1):583. Lightwood DJ, Munro RJ, Porter J, McMillan D, Carrington B, Turner A, Scott-Tucker A, Hickford ES, Schmidt A, Fox D, Maloney A, Ceska T, Bourne T, O'Connell J, Lawson ADG. PMID: 33495445; PMCID: PMC7835358.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    8. Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF. Nat Commun. 2021 01 25; 12(1):582. McMillan D, Martinez-Fleites C, Porter J, Fox D, Davis R, Mori P, Ceska T, Carrington B, Lawson A, Bourne T, O'Connell J. PMID: 33495441; PMCID: PMC7835368.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    9. Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis. Arthritis Res Ther. 2021 01 06; 23(1):10. Fox DA, Lundy SK, Whitfield ML, Berrocal V, Campbell P, Rasmussen S, Ohara R, Stinson A, Gurrea-Rubio M, Wiewiora E, Spino C, Bush E, Furst D, Pillai S, Khanna D. PMID: 33407866; PMCID: PMC7789011.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    10. Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis. Sci Adv. 2020 10; 6(44). O'Neil LJ, Barrera-Vargas A, Sandoval-Heglund D, Merayo-Chalico J, Aguirre-Aguilar E, Aponte AM, Ruiz-Perdomo Y, Gucek M, El-Gabalawy H, Fox DA, Katz JD, Kaplan MJ, Carmona-Rivera C. PMID: 33115748; PMCID: PMC7608797.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    11. Safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis (ASSET): open-label extension of a phase 2, double-blind randomised trial. Lancet Rheumatol. 2020 12; 2(12):e743-e753. Chung L, Spino C, McLain R, Johnson SR, Denton CP, Molitor JA, Steen VD, Lafyatis R, Simms RW, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon JK, Mayes MD, Sandorfi N, Hant FN, Bernstein EJ, Chatterjee S, Castelino FV, Ajam A, Allanore Y, Matucci-Cerinic M, Whitfield ML, Distler O, Singer O, Young A, Nagaraja V, Fox DA, Furst DE, Khanna D. PMID: 34966900; PMCID: PMC8713509.
      View in: PubMed   Mentions: 18     Fields:    
    12. Attenuation of Murine Collagen-Induced Arthritis by Targeting CD6. Arthritis Rheumatol. 2020 09; 72(9):1505-1513. Li Y, Ruth JH, Rasmussen SM, Athukorala KS, Weber DP, Amin MA, Campbell PL, Singer NG, Fox DA, Lin F. PMID: 32307907; PMCID: PMC7745675.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    13. Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis. JCI Insight. 2020 07 09; 5(13). Carmona-Rivera C, Carlucci PM, Goel RR, James E, Brooks SR, Rims C, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ. PMID: 32484790; PMCID: PMC7406272.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    14. HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):15884-15894. Ianiri G, Coelho MA, Ruchti F, Sparber F, McMahon TJ, Fu C, Bolejack M, Donovan O, Smutney H, Myler P, Dietrich F, Fox D, LeibundGut-Landmann S, Heitman J. PMID: 32576698; PMCID: PMC7354939.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    15. Real time visualization of cancer cell death, survival and proliferation using fluorochrome-transfected cells in an IncuCyte® imaging system. J Biol Methods. 2020; 7(2):e133. Lanigan TM, Rasmussen SM, Weber DP, Athukorala KS, Campbell PL, Fox DA, Ruth JH. PMID: 32577423; PMCID: PMC7300428.
      View in: PubMed   Mentions: 12  
    16. IRAK4 inhibition: a promising strategy for treating RA joint inflammation and bone erosion. Cell Mol Immunol. 2021 09; 18(9):2199-2210. Umar S, Palasiewicz K, Van Raemdonck K, Volin MV, Romay B, Amin MA, Zomorrodi RK, Arami S, Gonzalez M, Rao V, Zanotti B, Fox DA, Sweiss N, Shahrara S. PMID: 32415262; PMCID: PMC8429735.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    17. Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis. JCI Insight. 2020 02 13; 5(3). Wu Q, Mills EA, Wang Q, Dowling CA, Fisher C, Kirch B, Lundy SK, Fox DA, Mao-Draayer Y, AMS04 Study Group. PMID: 31935197; PMCID: PMC7098784.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    18. CD13/Aminopeptidase N Is a Potential Therapeutic Target for Inflammatory Disorders. J Immunol. 2020 01 01; 204(1):3-11. Lu C, Amin MA, Fox DA. PMID: 31848300; PMCID: PMC6997018.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    19. Georgia Abortion Law and Our Commitment to Patients. Arthritis Rheumatol. 2020 02; 72(2):377-378. Craft JE, Crow MK, Lockshin MD, Salmon JE, Diamond B, Elkon KB, Flood J, Fox DA, Gabriel SE, Gilkeson GS, Hahn BH, Hardin J, Koopman WJ, Seaman WE, Wofsy D, Sergent JS, Uknis AB, Weinblatt ME. PMID: 31637878.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice. Arthritis Res Ther. 2019 12 17; 21(1):292. Scarneo SA, Eibschutz LS, Bendele PJ, Yang KW, Totzke J, Hughes P, Fox DA, Haystead TAJ. PMID: 31847895; PMCID: PMC6918687.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    21. Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial. Arthritis Rheumatol. 2020 01; 72(1):125-136. Khanna D, Spino C, Johnson S, Chung L, Whitfield ML, Denton CP, Berrocal V, Franks J, Mehta B, Molitor J, Steen VD, Lafyatis R, Simms RW, Gill A, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon JK, Mayes MD, Schiopu E, Young A, Sandorfi N, Park J, Hant FN, Bernstein EJ, Chatterjee S, Castelino FV, Ajam A, Wang Y, Wood T, Allanore Y, Matucci-Cerinic M, Distler O, Singer O, Bush E, Fox DA, Furst DE. PMID: 31342624; PMCID: PMC6935399.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCTClinical Trials
    22. Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun. 2019 09 19; 10(1):4275. Juvvadi PR, Fox D, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, Lee SC, Chen YL, Mutz M, Spicer LD, Schumacher MA, Heitman J, Steinbach WJ. PMID: 31537789; PMCID: PMC6753081.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    23. Patterns of glucocorticoid prescribing and provider-level variation in a commercially insured incident rheumatoid arthritis population: A retrospective cohort study. Semin Arthritis Rheum. 2020 04; 50(2):228-236. Wallace BI, Lin P, Kamdar N, Noureldin M, Hayward R, Fox DA, Curtis JR, Saag KG, Waljee AK. PMID: 31522762; PMCID: PMC7060094.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Absence of complement component 3 does not prevent classical pathway-mediated hemolysis. Blood Adv. 2019 06 25; 3(12):1808-1814. Zhang L, Dai Y, Huang P, Saunders TL, Fox DA, Xu J, Lin F. PMID: 31196848; PMCID: PMC6595256.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    25. Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis. Arthritis Rheumatol. 2019 08; 71(8):1241-1251. Ohara RA, Edhayan G, Rasmussen SM, Isozaki T, Remmer HA, Lanigan TM, Campbell PL, Urquhart AG, Lawton JN, Chung KC, Fox DA, Ruth JH. PMID: 30861322; PMCID: PMC6663620.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    26. Macrophages are the primary effector cells in IL-7-induced arthritis. Cell Mol Immunol. 2020 07; 17(7):728-740. Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S. PMID: 31197255; PMCID: PMC7331600.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    27. Angiogenic and Arthritogenic Properties of the Soluble Form of CD13. J Immunol. 2019 07 15; 203(2):360-369. Du Y, Lu C, Morgan RL, Stinson WA, Campbell PL, Cealey E, Fu W, Lepore NJ, Hervoso JL, Cui H, Urquhart AG, Lawton JN, Chung KC, Fox DA, Amin MA. PMID: 31189572; PMCID: PMC6644048.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    28. Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders. J Med Chem. 2019 05 23; 62(10):4884-4901. Gurney ME, Nugent RA, Mo X, Sindac JA, Hagen TJ, Fox D, O'Donnell JM, Zhang C, Xu Y, Zhang HT, Groppi VE, Bailie M, White RE, Romero DL, Vellekoop AS, Walker JR, Surman MD, Zhu L, Campbell RF. PMID: 31013090; PMCID: PMC7444661.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    29. 5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma. J Med Chem. 2019 05 09; 62(9):4350-4369. Kahl DJ, Hutchings KM, Lisabeth EM, Haak AJ, Leipprandt JR, Dexheimer T, Khanna D, Tsou PS, Campbell PL, Fox DA, Wen B, Sun D, Bailie M, Neubig RR, Larsen SD. PMID: 30951312; PMCID: PMC6590913.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    30. Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds. ACS Pharmacol Transl Sci. 2019 Apr 12; 2(2):92-100. Lisabeth EM, Kahl D, Gopallawa I, Haynes SE, Misek SA, Campbell PL, Dexheimer TS, Khanna D, Fox DA, Jin X, Martin BR, Larsen SD, Neubig RR. PMID: 32039344; PMCID: PMC7006939.
      View in: PubMed   Mentions: 19  
    31. Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3695-3702. Tsou PS, Campbell P, Amin MA, Coit P, Miller S, Fox DA, Khanna D, Sawalha AH. PMID: 30755532; PMCID: PMC6397533.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    32. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice. Neuropsychopharmacology. 2018 10; 43(11):2299-2309. Zhang C, Xu Y, Chowdhary A, Fox D, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM. PMID: 30131563; PMCID: PMC6135860.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    33. Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis. Arthritis Rheumatol. 2018 06; 70(6):841-854. Mandelin AM, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR. PMID: 29439295; PMCID: PMC5984677.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    34. Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy. J Immunol. 2018 06 15; 200(12):4094-4101. Xu J, Zhang L, Xie M, Li Y, Huang P, Saunders TL, Fox DA, Rosenquist R, Lin F. PMID: 29695418; PMCID: PMC5988965.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    35. Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis". Sci Immunol. 2018 03 30; 3(21). Carmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ. PMID: 29602804; PMCID: PMC6497166.
      View in: PubMed   Mentions: 2     Fields:    
    36. The role of CD6 in autoimmune diseases. Cell Mol Immunol. 2018 11; 15(11):1001-1002. Fox DA. PMID: 29572546; PMCID: PMC6207704.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    37. Clinical and experimental evidence for targeting CD6 in immune-based disorders. Autoimmun Rev. 2018 May; 17(5):493-503. Consuegra-Fernández M, Lin F, Fox DA, Lozano F. PMID: 29526637.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    38. Targeting CD6 for the treatment of experimental autoimmune uveitis. J Autoimmun. 2018 06; 90:84-93. Zhang L, Li Y, Qiu W, Bell BA, Dvorina N, Baldwin WM, Singer N, Kern T, Caspi RR, Fox DA, Lin F. PMID: 29472120; PMCID: PMC5949263.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    39. A unique role for galectin-9 in angiogenesis and inflammatory arthritis. Arthritis Res Ther. 2018 02 12; 20(1):31. O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA. PMID: 29433546; PMCID: PMC5809993.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    40. IL-11 facilitates a novel connection between RA joint fibroblasts and endothelial cells. Angiogenesis. 2018 05; 21(2):215-228. Elshabrawy HA, Volin MV, Essani AB, Chen Z, McInnes IB, Van Raemdonck K, Palasiewicz K, Arami S, Gonzalez M, Ashour HM, Kim SJ, Zhou G, Fox DA, Shahrara S. PMID: 29327326; PMCID: PMC5878720.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    41. Establishing clinical severity for PROMIS® measures in adult patients with rheumatic diseases. Qual Life Res. 2018 Mar; 27(3):755-764. Nagaraja V, Mara C, Khanna PP, Namas R, Young A, Fox DA, Laing T, McCune WJ, Dodge C, Rizzo D, Almackenzie M, Khanna D. PMID: 28983738; PMCID: PMC5845827.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    42. Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease. Cell Chem Biol. 2017 Aug 17; 24(8):1029-1039.e7. Totzke J, Gurbani D, Raphemot R, Hughes PF, Bodoor K, Carlson DA, Loiselle DR, Bera AK, Eibschutz LS, Perkins MM, Eubanks AL, Campbell PL, Fox DA, Westover KD, Haystead TAJ, Derbyshire ER. PMID: 28820959; PMCID: PMC5576570.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    43. CD318 is a ligand for CD6. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):E6912-E6921. Enyindah-Asonye G, Li Y, Ruth JH, Spassov DS, Hebron KE, Zijlstra A, Moasser MM, Wang B, Singer NG, Cui H, Ohara RA, Rasmussen SM, Fox DA, Lin F. PMID: 28760953; PMCID: PMC5565428.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    44. Transforming growth factor β activated kinase 1: a potential therapeutic target for rheumatic diseases. Rheumatology (Oxford). 2017 07 01; 56(7):1060-1068. Fechtner S, Fox DA, Ahmed S. PMID: 27550296; PMCID: PMC5850516.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    45. Seven-Year Outcomes of the Silicone Arthroplasty in Rheumatoid Arthritis Prospective Cohort Study. Arthritis Care Res (Hoboken). 2017 07; 69(7):973-981. Chung KC, Kotsis SV, Burns PB, Burke FD, Wilgis EFS, Fox DA, Kim HM. PMID: 27696739; PMCID: PMC5376377.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    46. Synovial cellular and molecular markers in rheumatoid arthritis. Semin Immunopathol. 2017 06; 39(4):385-393. Asif Amin M, Fox DA, Ruth JH. PMID: 28497350; PMCID: PMC5521018.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    47. Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis. Sci Immunol. 2017 Apr; 2(10). Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, Kaplan MJ. PMID: 28649674; PMCID: PMC5479641.
      View in: PubMed   Mentions: 135     Fields:    
    48. Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. Bioorg Med Chem Lett. 2017 04 15; 27(8):1744-1749. Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD. PMID: 28285914; PMCID: PMC5395305.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    49. CD6 as a potential target for treating multiple sclerosis. Proc Natl Acad Sci U S A. 2017 03 07; 114(10):2687-2692. Li Y, Singer NG, Whitbred J, Bowen MA, Fox DA, Lin F. PMID: 28209777; PMCID: PMC5347585.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    50. DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis. Nat Commun. 2017 02 06; 8:14252. Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM. PMID: 28165452; PMCID: PMC5303823.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    51. TLRs, future potential therapeutic targets for RA. Autoimmun Rev. 2017 Feb; 16(2):103-113. Elshabrawy HA, Essani AE, Szekanecz Z, Fox DA, Shahrara S. PMID: 27988432; PMCID: PMC5290220.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    52. Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors. Arthritis Rheumatol. 2016 12; 68(12):2975-2985. Tsou PS, Wren JD, Amin MA, Schiopu E, Fox DA, Khanna D, Sawalha AH. PMID: 27482699; PMCID: PMC5125850.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    53. Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes. PLoS One. 2016; 11(9):e0162008. Morgan RL, Behbahani-Nejad N, Endres J, Amin MA, Lepore NJ, Du Y, Urquhart A, Chung KC, Fox DA. PMID: 27658265; PMCID: PMC5033571.
      View in: PubMed   Mentions: 15     Fields:    
    54. Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis. Arthritis Res Ther. 2016 Apr 12; 18:87. Edhayan G, Ohara RA, Stinson WA, Amin MA, Isozaki T, Ha CM, Haines GK, Morgan R, Campbell PL, Arbab AS, Friday SC, Fox DA, Ruth JH. PMID: 27071670; PMCID: PMC4830090.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    55. Phospholipase D enzymes facilitate IL-17- and TNFα-induced expression of proinflammatory genes in rheumatoid arthritis synovial fibroblasts (RASF). Immunol Lett. 2016 06; 174:9-18. Friday SC, Fox DA. PMID: 27058440.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    56. Activation of the Thromboxane A2 Receptor by 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma. J Invest Dermatol. 2015 Dec; 135(12):3153-3162. Tsou PS, Amin MA, Campbell PL, Zakhem G, Balogh B, Edhayan G, Ohara RA, Schiopu E, Khanna D, Koch AE, Fox DA. PMID: 26288351; PMCID: PMC4648660.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    57. Citrullination: A Specific Target for the Autoimmune Response in Rheumatoid Arthritis. J Immunol. 2015 Jul 01; 195(1):5-7. Fox DA. PMID: 26092811.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    58. Killer B lymphocytes and their fas ligand positive exosomes as inducers of immune tolerance. Front Immunol. 2015; 6:122. Lundy SK, Klinker MW, Fox DA. PMID: 25852690; PMCID: PMC4367442.
      View in: PubMed   Mentions: 21     Fields:    
    59. The incidence of upper and lower extremity surgery for rheumatoid arthritis among Medicare beneficiaries. J Bone Joint Surg Am. 2015 Mar 04; 97(5):403-10. Waljee J, Zhong L, Baser O, Yuce H, Fox DA, Chung KC. PMID: 25740031; PMCID: PMC4344595.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    60. Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice. Arthritis Rheumatol. 2015 Mar; 67(3):656-67. Mukai T, Gallant R, Ishida S, Kittaka M, Yoshitaka T, Fox DA, Morita Y, Nishida K, Rottapel R, Ueki Y. PMID: 25470448; PMCID: PMC4342302.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    61. Variation in rheumatoid hand and wrist surgery among medicare beneficiaries: a population-based cohort study. J Rheumatol. 2015 Mar; 42(3):429-36. Zhong L, Chung KC, Baser O, Fox DA, Yuce H, Waljee JF. PMID: 25593243; PMCID: PMC4827611.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    62. Expression and function of aminopeptidase N/CD13 produced by fibroblast-like synoviocytes in rheumatoid arthritis: role of CD13 in chemotaxis of cytokine-activated T cells independent of enzymatic activity. Arthritis Rheumatol. 2015 Jan; 67(1):74-85. Morgan R, Endres J, Behbahani-Nejad N, Phillips K, Ruth JH, Friday SC, Edhayan G, Lanigan T, Urquhart A, Chung KC, Fox DA. PMID: 25219368; PMCID: PMC4280337.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    63. Current and future approaches to the treatment of immunologic diseases: new targets and new therapeutic agents. Transl Res. 2015 Feb; 165(2):251-4. Fox DA. PMID: 25468483.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    64. Patient expectations and long-term outcomes in rheumatoid arthritis patients: results from the SARA (Silicone Arthroplasty in Rheumatoid Arthritis) study. Clin Rheumatol. 2015 Apr; 34(4):641-51. Chung KC, Nellans KW, Burns PB, Wilgis EF, Burke FD, Fox DA, Kim HM. PMID: 25267562; PMCID: PMC4374599.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    65. SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model. PLoS One. 2014; 9(8):e105518. Mukai T, Gallant R, Ishida S, Yoshitaka T, Kittaka M, Nishida K, Fox DA, Morita Y, Ueki Y. PMID: 25144740; PMCID: PMC4140794.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    66. Discovery of triazines as selective PDE4B versus PDE4D inhibitors. Bioorg Med Chem Lett. 2014 Aug 15; 24(16):4031-4. Hagen TJ, Mo X, Burgin AB, Fox D, Zhang Z, Gurney ME. PMID: 24998378; PMCID: PMC4142572.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    67. Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics. Arthritis Res Ther. 2014; 16(2):R90. Dennis G, Holweg CT, Kummerfeld SK, Choy DF, Setiadi AF, Hackney JA, Haverty PM, Gilbert H, Lin WY, Diehl L, Fischer S, Song A, Musselman D, Klearman M, Gabay C, Kavanaugh A, Endres J, Fox DA, Martin F, Townsend MJ. PMID: 25167216; PMCID: PMC4060385.
      View in: PubMed   Mentions: 165     Fields:    Translation:HumansCellsCTClinical Trials
    68. Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury. J Pharmacol Exp Ther. 2014 Jun; 349(3):480-6. Haak AJ, Tsou PS, Amin MA, Ruth JH, Campbell P, Fox DA, Khanna D, Larsen SD, Neubig RR. PMID: 24706986; PMCID: PMC4019321.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    69. The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability. Cell Res. 2014 May; 24(5):560-75. Fox D, Yan Z, Ling C, Zhao Y, Lee DY, Fukagawa T, Yang W, Wang W. PMID: 24699063; PMCID: PMC4011343.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    70. Human B Cell-Derived Lymphoblastoid Cell Lines Constitutively Produce Fas Ligand and Secrete MHCII(+)FasL(+) Killer Exosomes. Front Immunol. 2014; 5:144. Klinker MW, Lizzio V, Reed TJ, Fox DA, Lundy SK. PMID: 24765093; PMCID: PMC3980107.
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    71. T cell subsets and their role in the pathogenesis of rheumatic disease. Curr Opin Rheumatol. 2014 Mar; 26(2):204-10. Gizinski AM, Fox DA. PMID: 24445478.
      View in: PubMed   Mentions: 48  Translation:HumansAnimalsCells
    72. Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts. Arthritis Res Ther. 2014; 16(5):411. Tsou PS, Balogh B, Pinney AJ, Zakhem G, Lozier A, Amin MA, Stinson WA, Schiopu E, Khanna D, Fox DA, Koch AE. PMID: 25123250; PMCID: PMC4558991.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    73. Plasma CXCL9 elevations correlate with chronic GVHD diagnosis. Blood. 2014 Jan 30; 123(5):786-93. Kitko CL, Levine JE, Storer BE, Chai X, Fox DA, Braun TM, Couriel DR, Martin PJ, Flowers ME, Hansen JA, Chang L, Conlon M, Fiema BJ, Morgan R, Pongtornpipat P, Lamiman K, Ferrara JL, Lee SJ, Paczesny S. PMID: 24363401; PMCID: PMC3907763.
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    74. Noxa in rheumatic diseases: present understanding and future impact. Rheumatology (Oxford). 2014 Sep; 53(9):1539-46. Cottier KE, Fogle EM, Fox DA, Ahmed S. PMID: 24352336; PMCID: PMC4135581.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    75. Voriconazole-induced periostitis causing arthralgias mimicking a flare of granulomatosis with polyangiitis. J Clin Rheumatol. 2013 Dec; 19(8):444-5. Gladue HS, Fox DA. PMID: 24263147.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    76. Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis. Arthritis Res Ther. 2013 Nov 12; 15(6):R186. Marchesan JT, Gerow EA, Schaff R, Taut AD, Shin SY, Sugai J, Brand D, Burberry A, Jorns J, Lundy SK, Nuñez G, Fox DA, Giannobile WV. PMID: 24456966; PMCID: PMC3979094.
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    77. The effect of swan neck and boutonniere deformities on the outcome of silicone metacarpophalangeal joint arthroplasty in rheumatoid arthritis. Plast Reconstr Surg. 2013 Sep; 132(3):597-603. Chetta M, Burns PB, Kim HM, Burke FD, Wilgis EFS, Fox DA, Chung KC. PMID: 23985634; PMCID: PMC4153347.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    78. Interleukin-5 supports the expansion of fas ligand-expressing killer B cells that induce antigen-specific apoptosis of CD4(+) T cells and secrete interleukin-10. PLoS One. 2013; 8(8):e70131. Klinker MW, Reed TJ, Fox DA, Lundy SK. PMID: 23940537; PMCID: PMC3734024.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    79. Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation. Nat Neurosci. 2013 Sep; 16(9):1238-47. Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D, Qian Y, Martindale JL, Piao Y, Machamer J, Joshi SR, Mohanty S, Shaw AC, Lloyd TE, Brown GW, Ko MS, Gorospe M, Zou S, Wang W. PMID: 23912945; PMCID: PMC3853347.
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    80. Metacarpophalangeal implant surgery: time for a randomized clinical trial? Reply. Arthritis Care Res (Hoboken). 2013 Jun; 65(6):1014-5. Kim HM, Burns PB, Fox DA, Chung KC, Burke FD, Wilgis EF. PMID: 23335429.
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    81. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med. 2013 Mar 27; 5(178):178ra40. Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Gizinski A, Yalavarthi S, Knight JS, Friday S, Li S, Patel RM, Subramanian V, Thompson P, Chen P, Fox DA, Pennathur S, Kaplan MJ. PMID: 23536012; PMCID: PMC3727661.
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    82. Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling. Arthritis Rheum. 2013 Mar; 65(3):618-26. Ling S, Cline EN, Haug TS, Fox DA, Holoshitz J. PMID: 23233327; PMCID: PMC3582785.
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    83. The roles of IFN-γ versus IL-17 in pathogenic effects of human Th17 cells on synovial fibroblasts. Mod Rheumatol. 2013 Nov; 23(6):1140-50. Kato H, Endres J, Fox DA. PMID: 23306426; PMCID: PMC3710715.
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    84. Regulation of Th17 maturation by interleukin 4. Crit Rev Immunol. 2013; 33(5):379-87. Cooney LA, Fox DA. PMID: 24099299.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    85. Reflecting on early arthritis. J Rheumatol. 2012 Nov; 39(11):2059-61. Kovacs D, Torralba KD, Fox DA, Solomon DH, Panush RS. PMID: 23118276.
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    86. Long-term followup for rheumatoid arthritis patients in a multicenter outcomes study of silicone metacarpophalangeal joint arthroplasty. Arthritis Care Res (Hoboken). 2012 Sep; 64(9):1292-300. Chung KC, Burns PB, Kim HM, Burke FD, Wilgis EF, Fox DA. PMID: 22511483; PMCID: PMC3422446.
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    87. Kinase inhibition--a new approach to the treatment of rheumatoid arthritis. N Engl J Med. 2012 Aug 09; 367(6):565-7. Fox DA. PMID: 22873537.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    88. Treg cells to the rescue. Arthritis Rheum. 2012 Aug; 64(8):2426-8. Fox DA. PMID: 22605657.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    89. A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. Mol Cell. 2012 Jul 13; 47(1):61-75. Yan Z, Guo R, Paramasivam M, Shen W, Ling C, Fox D, Wang Y, Oostra AB, Kuehl J, Lee DY, Takata M, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Li L, Seidman MM, Wang W. PMID: 22705371; PMCID: PMC3398238.
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    90. Epilogue: how will we care for patients with early arthritis? Rheum Dis Clin North Am. 2012 May; 38(2):427-9. Panush RS, Quismorio FP, Fox DA. PMID: 22819093.
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    91. Sensitivity and resistance to regulation by IL-4 during Th17 maturation. J Immunol. 2011 Nov 01; 187(9):4440-50. Cooney LA, Towery K, Endres J, Fox DA. PMID: 21949021; PMCID: PMC3197869.
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    92. Properties of the International Classification for Functioning, Disability and Health in assessing hand outcomes in patients with rheumatoid arthritis. J Rehabil Med. 2011 Mar; 43(4):292-8. Chung KC, Burns PB, Reichert HA, Fox DA, Burke FD, Wilgis EF, Regan M, Kim HM. PMID: 21267527.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    93. A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis. Arthritis Res Ther. 2011 Feb 04; 13(1):R15. Wallis SK, Cooney LA, Endres JL, Lee MJ, Ryu J, Somers EC, Fox DA. PMID: 21294892; PMCID: PMC3241359.
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    94. Advances in the medical treatment of rheumatoid arthritis. Hand Clin. 2011 Feb; 27(1):11-20. Kahlenberg JM, Fox DA. PMID: 21176795; PMCID: PMC3135413.
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    95. Historical perspective on the etiology of rheumatoid arthritis. Hand Clin. 2011 Feb; 27(1):1-10. Entezami P, Fox DA, Clapham PJ, Chung KC. PMID: 21176794; PMCID: PMC3119866.
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    96. Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis? Clin Transl Sci. 2010 Dec; 3(6):319-26. Kato H, Fox DA. PMID: 21167010; PMCID: PMC3057561.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    97. Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication. EMBO J. 2010 Sep 15; 29(18):3140-55. Xu D, Muniandy P, Leo E, Yin J, Thangavel S, Shen X, Ii M, Agama K, Guo R, Fox D, Meetei AR, Wilson L, Nguyen H, Weng NP, Brill SJ, Li L, Vindigni A, Pommier Y, Seidman M, Wang W. PMID: 20711169; PMCID: PMC2944062.
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    98. Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets. Best Pract Res Clin Rheumatol. 2010 Aug; 24(4):463-77. Gizinski AM, Fox DA, Sarkar S. PMID: 20732645; PMCID: PMC3146352.
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    99. Validity and responsiveness of the Michigan Hand Questionnaire in patients with rheumatoid arthritis: a multicenter, international study. Arthritis Care Res (Hoboken). 2010 Nov; 62(11):1569-77. Waljee JF, Chung KC, Kim HM, Burns PB, Burke FD, Wilgis EF, Fox DA. PMID: 20521331; PMCID: PMC4386867.
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    100. Cell-cell interactions in rheumatoid arthritis synovium. Rheum Dis Clin North Am. 2010 May; 36(2):311-23. Fox DA, Gizinski A, Morgan R, Lundy SK. PMID: 20510236; PMCID: PMC2879397.
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    101. Preface: rheumatoid arthritis--halfway there. Rheum Dis Clin North Am. 2010 May; 36(2):xiii-xiv. Fox DA. PMID: 20510230.
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    102. Targeting IL-17 and Th17 cells in rheumatoid arthritis. Rheum Dis Clin North Am. 2010 May; 36(2):345-66. Sarkar S, Fox DA. PMID: 20510238.
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    103. Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers. Arthritis Rheum. 2010 May; 62(5):1319-28. Sakuta T, Morita Y, Satoh M, Fox DA, Kashihara N. PMID: 20213806.
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    104. Differences between the United States and the United Kingdom in the treatment of rheumatoid arthritis: analyses from a hand arthroplasty trial. Clin Rheumatol. 2010 Apr; 29(4):363-7. Chung KC, Kotsis SV, Fox DA, Regan M, Burke FD, Wilgis EF, Kim HM. PMID: 20077124; PMCID: PMC4386876.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    105. RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase. Mol Cell Biol. 2010 May; 30(10):2460-72. Islam MN, Fox D, Guo R, Enomoto T, Wang W. PMID: 20231364; PMCID: PMC2863711.
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    106. Outcomes of silicone arthroplasty for rheumatoid metacarpophalangeal joints stratified by fingers. J Hand Surg Am. 2009 Nov; 34(9):1647-52. Chung KC, Kotsis SV, Wilgis EF, Fox DA, Regan M, Kim HM, Burke FD. PMID: 19896008; PMCID: PMC4413434.
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    107. Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4. Arthritis Res Ther. 2009; 11(5):R158. Sarkar S, Cooney LA, White P, Dunlop DB, Endres J, Jorns JM, Wasco MJ, Fox DA. PMID: 19852819; PMCID: PMC2787258.
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    108. Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis. Arthritis Res Ther. 2009; 11(4):R128. Lundy SK, Fox DA. PMID: 19706160; PMCID: PMC2745812.
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    109. A prospective study comparing outcomes after reconstruction in rheumatoid arthritis patients with severe ulnar drift deformities. Plast Reconstr Surg. 2009 Jun; 123(6):1769-1777. Chung KC, Burke FD, Wilgis EFS, Regan M, Kim HM, Fox DA. PMID: 19483578; PMCID: PMC2735852.
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    110. A multicenter clinical trial in rheumatoid arthritis comparing silicone metacarpophalangeal joint arthroplasty with medical treatment. J Hand Surg Am. 2009 May-Jun; 34(5):815-23. Chung KC, Burns PB, Wilgis EF, Burke FD, Regan M, Kim HM, Fox DA. PMID: 19410984; PMCID: PMC4381953.
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    111. The future of ILAR. Clin Rheumatol. 2009 May; 28(5):493-4. Fox DA. PMID: 19252816.
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    112. Unity in the field of rheumatology: the role of the ACR. Arthritis Rheum. 2009 Feb; 60(2):313-6. Fox DA. PMID: 19180505.
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    113. Etanercept-associated pulmonary granulomatous inflammation in patients with rheumatoid arthritis. J Rheumatol. 2008 Nov; 35(11):2279-82. Ognenovski VM, Ojo TC, Fox DA. PMID: 19004058.
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    114. Regulatory T cells in rheumatoid arthritis. Curr Rheumatol Rep. 2008 Oct; 10(5):405-12. Sarkar S, Fox DA. PMID: 18817646.
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    115. CD19+CD5+ B cells in primary IgA nephropathy. J Am Soc Nephrol. 2008 Nov; 19(11):2130-9. Yuling H, Ruijing X, Xiang J, Yanping J, Lang C, Li L, Dingping Y, Xinti T, Jingyi L, Zhiqing T, Yongyi B, Bing X, Xinxing W, Youxin J, Fox DA, Lundy SK, Guohua D, Jinquan T. PMID: 18650480; PMCID: PMC2573008.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    116. Th17 cells in human disease. Immunol Rev. 2008 Jun; 223:87-113. Tesmer LA, Lundy SK, Sarkar S, Fox DA. PMID: 18613831; PMCID: PMC3299089.
      View in: PubMed   Mentions: 470     Fields:    Translation:HumansAnimalsCells
    117. High-throughput profiling of ion channel activity in primary human lymphocytes. Anal Chem. 2008 May 15; 80(10):3728-35. Estes DJ, Memarsadeghi S, Lundy SK, Marti F, Mikol DD, Fox DA, Mayer M. PMID: 18433147.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    118. Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3. J Immunol. 2008 Mar 01; 180(5):2989-98. Tran CN, Thacker SG, Louie DM, Oliver J, White PT, Endres JL, Urquhart AG, Chung KC, Fox DA. PMID: 18292521.
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    119. The past and the future of Arthritis & Rheumatism: a view from the American College of Rheumatology. Arthritis Rheum. 2008 Feb; 58(2 Suppl):S7-S10. Fox DA. PMID: 18240163.
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    120. Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cells. Am J Pathol. 2007 Nov; 171(5):1588-98. Tran CN, Lundy SK, White PT, Endres JL, Motyl CD, Gupta R, Wilke CM, Shelden EA, Chung KC, Urquhart AG, Fox DA. PMID: 17823284; PMCID: PMC2043519.
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    121. Fluvastatin reverses endothelial dysfunction and increased vascular oxidative stress in rat adjuvant-induced arthritis. Arthritis Rheum. 2007 Jun; 56(6):1827-35. Haruna Y, Morita Y, Yada T, Satoh M, Fox DA, Kashihara N. PMID: 17530711.
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    122. Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum. 2007 May; 56(5):1497-506. Tran CN, Davis MJ, Tesmer LA, Endres JL, Motyl CD, Smuda C, Somers EC, Chung KC, Urquhart AG, Lundy SK, Kovats S, Fox DA. PMID: 17469112.
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    123. Regulatory T cell defects in rheumatoid arthritis. Arthritis Rheum. 2007 Mar; 56(3):710-3. Sarkar S, Fox DA. PMID: 17328040.
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    124. Cells of the synovium in rheumatoid arthritis. T lymphocytes. Arthritis Res Ther. 2007; 9(1):202. Lundy SK, Sarkar S, Tesmer LA, Fox DA. PMID: 17306038; PMCID: PMC1860060.
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    125. Interleukin-17 as a molecular target in immune-mediated arthritis: immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4. Arthritis Rheum. 2007 Jan; 56(1):89-100. Sarkar S, Tesmer LA, Hindnavis V, Endres JL, Fox DA. PMID: 17195211.
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    126. Endothelial dysfunction in rat adjuvant-induced arthritis: vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase. Arthritis Rheum. 2006 Jun; 54(6):1847-55. Haruna Y, Morita Y, Komai N, Yada T, Sakuta T, Tomita N, Fox DA, Kashihara N. PMID: 16729278.
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    127. Treatment for rheumatic disorders. N Engl J Med. 2006 Mar 23; 354(12):1322-3. Tindall EA, Fox DA. PMID: 16554540.
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    128. Immunocompetent properties of human osteoblasts: interactions with T lymphocytes. J Bone Miner Res. 2006 Jan; 21(1):29-36. Stanley KT, VanDort C, Motyl C, Endres J, Fox DA. PMID: 16355271.
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    129. Synovial biology and T cells in rheumatoid arthritis. Pathophysiology. 2005 Oct; 12(3):183-9. Tran CN, Lundy SK, Fox DA. PMID: 16112560; PMCID: PMC3533491.
      View in: PubMed   Mentions: 41  
    130. Cytokine production by dendritic cells genetically engineered to express IL-4: induction of Th2 responses and differential regulation of IL-12 and IL-23 synthesis. J Gene Med. 2005 Jul; 7(7):869-77. Morita Y, Gupta R, Seidl KM, McDonagh KT, Fox DA. PMID: 15712252.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    131. Dendritic cells in rheumatoid arthritis. Front Biosci. 2005 Jan 01; 10:656-65. Sarkar S, Fox DA. PMID: 15569606.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    132. Expression and characterization of a novel CD6 ligand in cells derived from joint and epithelial tissues. J Immunol. 2004 Nov 15; 173(10):6125-33. Saifullah MK, Fox DA, Sarkar S, Abidi SM, Endres J, Piktel J, Haqqi TM, Singer NG. PMID: 15528349.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    133. Xenogeneic cells and superantigen induce human T-cell activation in the absence of T-cell recognition of xenoantigen. J Lab Clin Med. 2003 Sep; 142(3):149-57. Diaz LA, Pai R, Endres J, Anthony P, Duzyj C, Bishu S, Morita Y, Fox DA. PMID: 14532902.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    134. Surgical management of the rheumatoid hand: consensus and controversy among rheumatologists and hand surgeons. J Rheumatol. 2003 Jul; 30(7):1464-72. Alderman AK, Ubel PA, Kim HM, Fox DA, Chung KC. PMID: 12858442.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    135. Effectiveness of rheumatoid hand surgery: contrasting perceptions of hand surgeons and rheumatologists. J Hand Surg Am. 2003 Jan; 28(1):3-11; discussion 12-3. Alderman AK, Chung KC, Kim HM, Fox DA, Ubel PA. PMID: 12563630.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    136. CD6: expression during development, apoptosis and selection of human and mouse thymocytes. Int Immunol. 2002 Jun; 14(6):585-97. Singer NG, Fox DA, Haqqi TM, Beretta L, Endres JS, Prohaska S, Parnes JR, Bromberg J, Sramkoski RM. PMID: 12039910.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
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