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David Young, MD

Photo of David Young, MD
Title(s)Professor, Surgery
SchoolSchool of Medicine
Address513 Parnassus Avenue, MSB, #549A
San Francisco CA 94143
Phone415-206-8814
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    Collapse Biography 
    Collapse education and training
    University of California, San FranciscoResidency

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    HYPOXIA INDUCIBLE FACTOR-1. &DELAYED WOUND HEALING
    NIH R01GM068778Sep 1, 2004 - Aug 31, 2010
    Role: Principal Investigator
    ROLE OF HEAT SHOCK PROTEINS IN CUTANEOUS BURN INJURY
    NIH K08GM000674Sep 30, 1999 - Sep 29, 2004
    Role: Principal Investigator
    STUDY OF TRANSPLANTED ALLO-DERMIS &EPIDERMIS
    NIH F32GM014121Dec 31, 1990
    Role: Principal Investigator
    Academic Training in Trauma and Burns
    NIH T32GM008258Jul 1, 1988 - Jun 30, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Five autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes. Cell Rep. 2024 06 25; 43(6):114329. Fazel Darbandi S, An JY, Lim K, Page NF, Liang L, Young DM, Ypsilanti AR, State MW, Nord AS, Sanders SJ, Rubenstein JLR. PMID: 38850535; PMCID: PMC11235582.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    2. A comprehensive AI model development framework for consistent Gleason grading. Commun Med (Lond). 2024 May 09; 4(1):84. Huo X, Ong KH, Lau KW, Gole L, Young DM, Tan CL, Zhu X, Zhang C, Zhang Y, Li L, Han H, Lu H, Zhang J, Hou J, Zhao H, Gan H, Yin L, Wang X, Chen X, Lv H, Cao H, Yu X, Shi Y, Huang Z, Marini G, Xu J, Liu B, Chen B, Wang Q, Gui K, Shi W, Sun Y, Chen W, Cao D, Sanders SJ, Lee HK, Hue SS, Yu W, Tan SY. PMID: 38724730; PMCID: PMC11082180.
      View in: PubMed   Mentions: 3  
    3. Artificial intelligence-assisted quantification and assessment of whole slide images for pediatric kidney disease diagnosis. Bioinformatics. 2024 01 02; 40(1). Feng C, Ong K, Young DM, Chen B, Li L, Huo X, Lu H, Gu W, Liu F, Tang H, Zhao M, Yang M, Zhu K, Huang L, Wang Q, Marini GPL, Gui K, Han H, Sanders SJ, Li L, Yu W, Mao J. PMID: 38058211; PMCID: PMC10796177.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Automatic DNA replication tract measurement to assess replication and repair dynamics at the single-molecule level. Bioinformatics. 2022 09 15; 38(18):4395-4402. Li L, Kolinjivadi AM, Ong KH, Young DM, Marini GPL, Chan SH, Chong ST, Chew EL, Lu H, Gole L, Yu W, Ngeow J. PMID: 35881697; PMCID: PMC9477523.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    5. Detection of subtle white matter lesions in MRI through texture feature extraction and boundary delineation using an embedded clustering strategy. Sci Rep. 2022 03 15; 12(1):4433. Ong K, Young DM, Sulaiman S, Shamsuddin SM, Mohd Zain NR, Hashim H, Yuen K, Sanders SJ, Yu W, Hang S. PMID: 35292654; PMCID: PMC8924181.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Preventing Recurrence in Clean and Contaminated Hernias Using Biologic Versus Synthetic Mesh in Ventral Hernia Repair: The PRICE Randomized Clinical Trial. Ann Surg. 2021 04 01; 273(4):648-655. Harris HW, Primus F, Young C, Carter JT, Lin M, Mukhtar RA, Yeh B, Allen IE, Freise C, Kim E, Sbitany H, Young DM, Hansen S. PMID: 33443907.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansPHPublic Health
    7. Constructing and optimizing 3D atlases from 2D data with application to the developing mouse brain. Elife. 2021 02 11; 10. Young DM, Fazel Darbandi S, Schwartz G, Bonzell Z, Yuruk D, Nojima M, Gole LC, Rubenstein JL, Yu W, Sanders SJ. PMID: 33570495; PMCID: PMC7994002.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    8. Satellite cell activation and retention of muscle regenerative potential after long-term denervation. Stem Cells. 2021 03; 39(3):331-344. Wong A, Garcia SM, Tamaki S, Striedinger K, Barruet E, Hansen SL, Young DM, Pomerantz JH. PMID: 33326654.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    9. Whole-Brain Image Analysis and Anatomical Atlas 3D Generation Using MagellanMapper. Curr Protoc Neurosci. 2020 12; 94(1):e104. Young DM, Duhn C, Gilson M, Nojima M, Yuruk D, Kumar A, Yu W, Sanders SJ. PMID: 32981139; PMCID: PMC7781073.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    10. Contemporary concepts in hernia prevention: Selected proceedings from the 2017 International Symposium on Prevention of Incisional Hernias. Surgery. 2018 08; 164(2):319-326. Harris HW, Hope WH, Adrales G, Andersen DK, Deerenberg EB, Diener H, Dumanian G, East B, Fischer JP, Ureña MAG, Gibeily GJ, Hansson BM, Hernández-Granados P, Hiles MC, Jeekel J, Levinson H, Lopez-Cano M, Muysoms F, Pereira JA, Prudhomme M, Ramaswamy A, Stabilini C, Torkington J, Valverde S, Young DM. PMID: 29705098.
      View in: PubMed   Mentions: 5     Fields:    
    11. Silver microparticles plus fibrin tissue sealant prevents incisional hernias in rats. J Surg Res. 2018 07; 227:130-136. Primus FE, Young DM, Grenert JP, Harris HW. PMID: 29804844.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    12. Biopolymer Molecular Weight Can Modulate the Wound Healing Efficacy of Multivalent Sonic Hedgehog-Hyaluronic Acid Conjugates. Biomacromolecules. 2017 Aug 14; 18(8):2350-2359. Holstlaw TA, Mahomed M, Brier LW, Young DM, Boudreau NJ, Jackson WM. PMID: 28679037; PMCID: PMC5825181.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    13. The effects of immunosuppressive medications on outcomes in microvascular free tissue transfer. Plast Reconstr Surg. 2014 Apr; 133(4):552e-558e. Sbitany H, Xu X, Hansen SL, Young DM, Hoffman WY. PMID: 24675207.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. Klotho mice: a novel wound model of aged skin. Plast Reconstr Surg Glob Open. 2014 Jan; 2(1):e101. Yamashita K, Yotsuyanagi T, Yamauchi M, Young DM. PMID: 25289288; PMCID: PMC4174222.
      View in: PubMed   Mentions: 8  
    15. Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. J Mol Med (Berl). 2012 May; 90(5):575-85. Yang SB, Lee HY, Young DM, Tien AC, Rowson-Baldwin A, Shu YY, Jan YN, Jan LY. PMID: 22105852; PMCID: PMC3354320.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    16. Application of the chemokine CXCL12 expression plasmid restores wound healing to near normal in a diabetic mouse model. J Trauma. 2010 Aug; 69(2):392-8. Restivo TE, Mace KA, Harken AH, Young DM. PMID: 20699749.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    17. Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11074-9. Young DM, Schenk AK, Yang SB, Jan YN, Jan LY. PMID: 20534473; PMCID: PMC2890736.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimals
    18. Open incisional hernia repair at an academic tertiary care medical center. Arch Surg. 2009 Sep; 144(9):848-52. Mohebali K, Young DM, Hansen SL, Shawo A, Freise CE, Chang DS, Maa J, Harris HW. PMID: 19797110.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. HOXA3 modulates injury-induced mobilization and recruitment of bone marrow-derived cells. Stem Cells. 2009 Jul; 27(7):1654-65. Mace KA, Restivo TE, Rinn JL, Paquet AC, Chang HY, Young DM, Boudreau NJ. PMID: 19544454; PMCID: PMC2733377.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    20. Sustained expression of Hif-1alpha in the diabetic environment promotes angiogenesis and cutaneous wound repair. Wound Repair Regen. 2007 Sep-Oct; 15(5):636-45. Mace KA, Yu DH, Paydar KZ, Boudreau N, Young DM. PMID: 17971009.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    21. Effects of decreased insulin-like growth factor-1 stimulation on hypoxia inducible factor 1-alpha protein synthesis and function during cutaneous repair in diabetic mice. Wound Repair Regen. 2007 Sep-Oct; 15(5):628-35. Yu DH, Mace KA, Hansen SL, Boudreau N, Young DM. PMID: 17971008.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    22. Antibiotic use in the treatment of soft tissue abscesses: a survey of current practice. Surg Infect (Larchmt). 2007 Apr; 8(2):237-8. Rajendran PM, Young DM, Maurer T, Chambers HF, Jacobson MA, Harris HW. PMID: 17437370.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Inappropriate antibiotic use in soft tissue infections. Arch Surg. 2006 Sep; 141(9):850-4; discussion 855-6. Paydar KZ, Hansen SL, Charlebois ED, Harris HW, Young DM. PMID: 16983028.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    24. Hemangiomas and homeobox gene expression. J Craniofac Surg. 2006 Jul; 17(4):767-71. Hansen SL, Dosanjh A, Young DM, Boudreau N, Hoffman WY. PMID: 16877932.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair. J Cell Sci. 2005 Jun 15; 118(Pt 12):2567-77. Mace KA, Hansen SL, Myers C, Young DM, Boudreau N. PMID: 15914537.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    26. Photochemically knocking out glutamate receptors in vivo. J Am Chem Soc. 2004 Nov 03; 126(43):13886-7. Chambers JJ, Gouda H, Young DM, Kuntz ID, England PM. PMID: 15506725.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    27. An epidemic of methicillin-resistant Staphylococcus aureus soft tissue infections among medically underserved patients. Arch Surg. 2004 Sep; 139(9):947-51; discussion 951-3. Young DM, Harris HW, Charlebois ED, Chambers H, Campbell A, Perdreau-Remington F, Lee C, Mankani M, Mackersie R, Schecter WP. PMID: 15381611.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCellsPHPublic Health
    28. HoxD3 accelerates wound healing in diabetic mice. Am J Pathol. 2003 Dec; 163(6):2421-31. Hansen SL, Myers CA, Charboneau A, Young DM, Boudreau N. PMID: 14633614; PMCID: PMC1892363.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    29. HoxD3 expression and collagen synthesis in diabetic fibroblasts. Wound Repair Regen. 2003 Nov-Dec; 11(6):474-80. Hansen SL, Young DM, Boudreau NJ. PMID: 14617289.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    30. Care of injection drug users with soft tissue infections in San Francisco, California. Arch Surg. 2002 Nov; 137(11):1217-22. Harris HW, Young DM. PMID: 12413304.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
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