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Eric Lam, PhD

Title(s)Assistant Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th St
San Francisco CA 94158
Phone--
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Reciprocal regulation between GCN2 (eIF2AK4) and PERK (eIF2AK3) through the JNK-FOXO3 axis to modulate cancer drug resistance and clonal survival. Mol Cell Endocrinol. 2020 Jun 29; 110932. Alasiri G, Jiramongkol Y, Trakansuebkul S, Ke HL, Mahmud Z, Intuyod K, Lam EW. PMID: 32615282.
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    2. Structural basis for Ca2+-dependent activation of a plant metacaspase. Nat Commun. 2020 May 07; 11(1):2249. Zhu P, Yu XH, Wang C, Zhang Q, Liu W, McSweeney S, Shanklin J, Lam E, Liu Q. PMID: 32382010.
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    3. FOXO transcription factor family in cancer and metastasis. Cancer Metastasis Rev. 2020 May 05. Jiramongkol Y, Lam EW. PMID: 32372224.
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    4. Senescent stromal cells promote cancer resistance through SIRT1 loss-potentiated overproduction of small extracellular vesicles. Cancer Res. 2020 May 04. Han L, Long Q, Li S, Xu Q, Zhang B, Dou X, Qian M, Jiramongkol Y, Guo J, Cao L, Chin YE, Lam EW, Jiang J, Sun Y. PMID: 32366480.
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    5. Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases. Trends Biochem Sci. 2020 Jul; 45(7):578-592. Song S, Lam EW, Tchkonia T, Kirkland JL, Sun Y. PMID: 32531228.
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    6. ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin. Nucleic Acids Res. 2020 03 18; 48(5):2676-2693. Tanaka I, Chakraborty A, Saulnier O, Benoit-Pilven C, Vacher S, Labiod D, Lam EWF, Bièche I, Delattre O, Pouzoulet F, Auboeuf D, Vagner S, Dutertre M. PMID: 31943118.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2. Cancers (Basel). 2020 Feb 26; 12(3). Leung MH, Tsoi H, Gong C, Man EP, Zona S, Yao S, Lam EW, Khoo US. PMID: 32110852.
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    8. Phosphorylation independent eIF4E translational reprogramming of selective mRNAs determines tamoxifen resistance in breast cancer. Oncogene. 2020 Apr; 39(15):3206-3217. Gong C, Tsoi H, Mok KC, Cheung J, Man EPS, Fujino K, Wong A, Lam EWF, Khoo US. PMID: 32066877.
      View in: PubMed   Mentions: 1     Fields:    
    9. Multifaceted Oncogenic Role of Adipocytes in the Tumour Microenvironment. Adv Exp Med Biol. 2020; 1219:125-142. Jiramongkol Y, Lam EW. PMID: 32130697.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Lapatinib sensitivity in nasopharyngeal carcinoma is modulated by SIRT2-mediated FOXO3 deacetylation. BMC Cancer. 2019 Nov 14; 19(1):1106. Aimjongjun S, Mahmud Z, Jiramongkol Y, Alasiri G, Yao S, Yagüe E, Janvilisri T, Lam EW. PMID: 31727006.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. Aging Cell. 2019 12; 18(6):e13027. Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, Qian M, Guo J, Xu J, Cao L, Chin YE, Coppé JP, Lam EW, Campisi J, Sun Y. PMID: 31493351.
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    12. EP300 and SIRT1/6 Co-Regulate Lapatinib Sensitivity Via Modulating FOXO3-Acetylation and Activity in Breast Cancer. Cancers (Basel). 2019 Jul 28; 11(8). Mahmud Z, Gomes AR, Lee HJ, Aimjongjun S, Jiramongkol Y, Yao S, Zona S, Alasiri G, Gong G, Yagüe E, Lam EW. PMID: 31357743.
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    13. Single-cell reconstruction of follicular remodeling in the human adult ovary. Nat Commun. 2019 07 18; 10(1):3164. Fan X, Bialecka M, Moustakas I, Lam E, Torrens-Juaneda V, Borggreven NV, Trouw L, Louwe LA, Pilgram GSK, Mei H, van der Westerlaken L, Chuva de Sousa Lopes SM. PMID: 31320652.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. Regulation of PERK expression by FOXO3: a vulnerability of drug-resistant cancer cells. Oncogene. 2019 09; 38(36):6382-6398. Alasiri G, Jiramongkol Y, Zona S, Fan LY, Mahmud Z, Gong G, Lee HJ, Lam EW. PMID: 31312024.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    15. Molecular mechanism of Forkhead box M1 inhibition by thiostrepton in breast cancer cells. Oncol Rep. 2019 Sep; 42(3):953-962. Kongsema M, Wongkhieo S, Khongkow M, Lam EW, Boonnoy P, Vongsangnak W, Wong-Ekkabut J. PMID: 31322278.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    16. BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity. Epigenetics Chromatin. 2019 07 02; 12(1):39. Khoueiry P, Ward Gahlawat A, Petretich M, Michon AM, Simola D, Lam E, Furlong EE, Benes V, Dawson MA, Prinjha RK, Drewes G, Grandi P. PMID: 31266503.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    17. Activation of Aurora A kinase increases YAP stability via blockage of autophagy. Cell Death Dis. 2019 06 03; 10(6):432. Wang P, Gong Y, Guo T, Li M, Fang L, Yin S, Kamran M, Liu Y, Xu J, Xu L, Peng F, Xue X, Yang M, Hung MC, Lam EW, Gu C, Wang C, Zhan Q, Liu Q. PMID: 31160567.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. Correction: FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer. Oncogene. 2019 Jun; 38(25):5111-5112. Karadedou CT, Gomes AR, Chen J, Petkovic M, Ho KK, Zwolinska AK, Feltes A, Wong SY, Chan KYK, Cheung YN, Tsang JWH, Brosens JJ, Khoo US, Lam EW. PMID: 30867566.
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    19. Promyelocytic leukemia protein (PML) controls breast cancer cell proliferation by modulating Forkhead transcription factors. Mol Oncol. 2019 06; 13(6):1369-1387. Sachini N, Arampatzi P, Klonizakis A, Nikolaou C, Makatounakis T, Lam EW, Kretsovali A, Papamatheakis J. PMID: 30927552.
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    20. The Critical Role of Dysregulated RhoB Signaling Pathway in Radioresistance of Colorectal Cancer. Int J Radiat Oncol Biol Phys. 2019 08 01; 104(5):1153-1164. Liu N, Cui W, Jiang X, Zhang Z, Gnosa S, Ali Z, Jensen L, Jönsson JI, Blockhuys S, Lam EW, Zhao Z, Ping J, Xie N, Kopsida M, Wang X, Sun XF. PMID: 31039421.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    21. Extracellular vesicles in the tumor microenvironment: old stories, but new tales. Mol Cancer. 2019 03 30; 18(1):59. Han L, Lam EW, Sun Y. PMID: 30925927.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    22. FOXK2 Transcription Factor and Its Emerging Roles in Cancer. Cancers (Basel). 2019 Mar 20; 11(3). Nestal de Moraes G, Carneiro LDT, Maia RC, Lam EW, Sharrocks AD. PMID: 30897782.
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    23. Oncogenic EP300 can be targeted with inhibitors of aldo-keto reductases. Biochem Pharmacol. 2019 05; 163:391-403. Mahmud Z, Asaduzzaman M, Kumar U, Masrour N, Jugov R, Coombes RC, Shousha S, Hu Y, Lam EW, Yagüe E. PMID: 30862505.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    24. The prognostic landscape of interactive biological processes presents treatment responses in cancer. EBioMedicine. 2019 Mar; 41:120-133. He B, Gao R, Lv D, Wen Y, Song L, Wang X, Lin S, Huang Q, Deng Z, Wang Z, Yan M, Zheng F, Lam EW, Kelley KW, Li Z, Liu Q. PMID: 30799199.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    25. FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expression. Sci Rep. 2019 02 06; 9(1):1505. Varghese V, Magnani L, Harada-Shoji N, Mauri F, Szydlo RM, Yao S, Lam EW, Kenny LM. PMID: 30728402.
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    26. Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells. J Clin Invest. 2019 03 01; 129(3):1030-1046. Cui B, Luo Y, Tian P, Peng F, Lu J, Yang Y, Su Q, Liu B, Yu J, Luo X, Yin L, Cheng W, An F, He B, Liang D, Wu S, Chu P, Song L, Liu X, Luo H, Xu J, Pan Y, Wang Y, Li D, Huang P, Yang Q, Zhang L, Zhou BP, Liu S, Xu G, Lam EW, Kelley KW, Liu Q. PMID: 30688660.
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    27. The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation. Oncogene. 2019 04; 38(17):3216-3231. Parzych K, Saavedra-García P, Valbuena GN, Al-Sadah HA, Robinson ME, Penfold L, Kuzeva DM, Ruiz-Tellez A, Loaiza S, Holzmann V, Caputo V, Johnson DC, Kaiser MF, Karadimitris A, Lam EW, Chevet E, Feldhahn N, Keun HC, Auner HW. PMID: 30626938.
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    28. Characterization of FOXO Acetylation. Methods Mol Biol. 2019; 1890:77-90. Yao S, Mahmud Z, Sachini N, Aimjongjun S, Saavedra-García P, Lam EW. PMID: 30414146.
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    29. Validation of the St. Paul's Endoscopy Comfort Scale (SPECS) for Colonoscopy. J Can Assoc Gastroenterol. 2020 Apr; 3(2):91-95. Telford J, Tavakoli I, Takach O, Kwok R, Harris N, Yonge J, Galorpart C, Whittaker S, Amar J, Rosenfeld G, Ko HH, Lam E, Ramji A, Bressler B, Enns R. PMID: 32328548.
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    30. FOXM1 modulates 5-fluorouracil sensitivity in cholangiocarcinoma through thymidylate synthase (TYMS): implications of FOXM1-TYMS axis uncoupling in 5-FU resistance. Cell Death Dis. 2018 12 11; 9(12):1185. Intuyod K, Saavedra-García P, Zona S, Lai CF, Jiramongkol Y, Vaeteewoottacharn K, Pairojkul C, Yao S, Yong JS, Trakansuebkul S, Waraasawapati S, Luvira V, Wongkham S, Pinlaor S, Lam EW. PMID: 30538221.
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    31. Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis. Elife. 2018 12 03; 7. Vervoort SJ, de Jong OG, Roukens MG, Frederiks CL, Vermeulen JF, Lourenço AR, Bella L, Vidakovic AT, Sandoval JL, Moelans C, van Amersfoort M, Dallman MJ, Bruna A, Caldas C, Nieuwenhuis E, van der Wall E, Derksen P, van Diest P, Verhaar MC, Lam EW, Mokry M, Coffer PJ. PMID: 30507376.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    32. Senescent cells: A new Achilles' heel to exploit for cancer medicine? Aging Cell. 2019 02; 18(1):e12875. Zhang B, Lam EW, Sun Y. PMID: 30450821.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Estrogen receptor ß upregulated by lncRNA-H19 to promote cancer stem-like properties in papillary thyroid carcinoma. Cell Death Dis. 2018 11 02; 9(11):1120. Li M, Chai HF, Peng F, Meng YT, Zhang LZ, Zhang L, Zou H, Liang QL, Li MM, Mao KG, Sun DX, Tong MY, Deng ZQ, Hou ZJ, Zhao Y, Li J, Wang XC, Lv SS, Zhang QQ, Yu X, Lam EW, Liu Q, Cui XN, Xu J. PMID: 30389909.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    34. Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance. Nat Commun. 2018 10 17; 9(1):4315. Chen F, Long Q, Fu D, Zhu D, Ji Y, Han L, Zhang B, Xu Q, Liu B, Li Y, Wu S, Yang C, Qian M, Xu J, Liu S, Cao L, Chin YE, Lam EW, Coppé JP, Sun Y. PMID: 30333494.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    35. Cellular Senescence: The Sought or the Unwanted? Trends Mol Med. 2018 10; 24(10):871-885. Sun Y, Coppé JP, Lam EW. PMID: 30153969.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    36. Chemotherapy-induced apoptosis, autophagy and cell cycle arrest are key drivers of synergy in chemo-immunotherapy of epithelial ovarian cancer. Cancer Immunol Immunother. 2018 11; 67(11):1753-1765. Wahba J, Natoli M, Whilding LM, Parente-Pereira AC, Jung Y, Zona S, Lam EW, Smith JR, Maher J, Ghaem-Maghami S. PMID: 30167862.
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    37. Cyclin D1 depletion interferes with oxidative balance and promotes cancer cell senescence. J Cell Sci. 2018 06 25; 131(12). Laphanuwat P, Likasitwatanakul P, Sittithumcharee G, Thaphaengphan A, Chomanee N, Suppramote O, Ketaroonrut N, Charngkaew K, Lam EW, Okada S, Panich U, Sampattavanich S, Jirawatnotai S. PMID: 29880532.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    38. O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1. Oncogene. 2018 10; 37(42):5648-5665. Phoomak C, Silsirivanit A, Park D, Sawanyawisuth K, Vaeteewoottacharn K, Wongkham C, Lam EW, Pairojkul C, Lebrilla CB, Wongkham S. PMID: 29915392.
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    39. Rate of Corticosteroid-Induced Mood Changes in Patients with Inflammatory Bowel Disease: A Prospective Study. J Can Assoc Gastroenterol. 2018 Sep; 1(3):99-106. Ou G, Bressler B, Galorport C, Lam E, Ko HH, Enns R, Telford J, Schaffer N, Lee T, Rosenfeld G. PMID: 31294728.
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    40. Reduced FOXM1 Expression Limits Trophoblast Migration and Angiogenesis and Is Associated With Preeclampsia. Reprod Sci. 2019 05; 26(5):580-590. Monteiro LJ, Cubillos S, Sanchez M, Acuña-Gallardo S, Venegas P, Herrera V, Lam EW, Varas-Godoy M, Illanes SE. PMID: 29848205.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    41. The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1. Nat Commun. 2018 04 30; 9(1):1723. Zhang B, Fu D, Xu Q, Cong X, Wu C, Zhong X, Ma Y, Lv Z, Chen F, Han L, Qian M, Chin YE, Lam EW, Chiao P, Sun Y. PMID: 29712904.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    42. A Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Fine-Needle Biopsy in the Diagnosis of Solid Pancreatic Lesions. Can J Gastroenterol Hepatol. 2018; 2018:1415062. Ayres LR, Kmiotek EK, Lam E, Telford JJ. PMID: 29850451.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. SUMOylation modulates FOXK2-mediated paclitaxel sensitivity in breast cancer cells. Oncogenesis. 2018 Mar 13; 7(3):29. Nestal de Moraes G, Ji Z, Fan LY, Yao S, Zona S, Sharrocks AD, Lam EW. PMID: 29540677.
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    44. BQ323636.1, a Novel Splice Variant to NCOR2, as a Predictor for Tamoxifen-Resistant Breast Cancer. Clin Cancer Res. 2018 08 01; 24(15):3681-3691. Gong C, Man EPS, Tsoi H, Lee TKW, Lee P, Ma ST, Wong LS, Luk MY, Rakha EA, Green AR, Ellis IO, Lam EW, Cheung KL, Khoo US. PMID: 29420220.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    45. Correction to: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer. Breast Cancer Res Treat. 2018 01; 167(2):605-606. Asaduzzaman M, Constantinou S, Min H, Gallon J, Lin ML, Singh P, Raguz S, Ali S, Shousha S, Charles Coombes R, Lam EW, Hu Y, Yagüe E. PMID: 29305809.
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    46. Metabolomics reveals novel blood plasma biomarkers associated to the BRCA1-mutated phenotype of human breast cancer. Sci Rep. 2017 12 19; 7(1):17831. Roig B, Rodríguez-Balada M, Samino S, Lam EW, Guaita-Esteruelas S, Gomes AR, Correig X, Borràs J, Yanes O, Gumà J. PMID: 29259228.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    47. Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia. Oncogene. 2018 02 22; 37(8):1119. Peng F, Wang JH, Fan WJ, Meng YT, Li MM, Li TT, Cui B, Wang HF, Zhao Y, An F, Guo T, Liu XF, Zhang L, Lv L, Lv DK, Xu LZ, Xie JJ, Lin WX, Lam EW, Xu J, Liu Q. PMID: 29251717.
      View in: PubMed   Mentions: 5     Fields:    
    48. The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance. Semin Cancer Biol. 2018 06; 50:77-89. Yao S, Fan LY, Lam EW. PMID: 29180117.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    49. Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia. Oncogene. 2018 02 22; 37(8):1062-1074. Peng F, Wang JH, Fan WJ, Meng YT, Li MM, Li TT, Cui B, Wang HF, Zhao Y, An F, Guo T, Liu XF, Zhang L, Lv L, Lv DK, Xu LZ, Xie JJ, Lin WX, Lam EW, Xu J, Liu Q. PMID: 29106390.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    50. p62/SQSTM1 interacts with vimentin to enhance breast cancer metastasis. Carcinogenesis. 2017 10 26; 38(11):1092-1103. Li SS, Xu LZ, Zhou W, Yao S, Wang CL, Xia JL, Wang HF, Kamran M, Xue XY, Dong L, Wang J, Ding XD, Bella L, Bugeon L, Xu J, Zheng FM, Dallman MJ, Lam EWF, Liu Q. PMID: 28968743.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    51. Extracellular vesicles in the tumor microenvironment: Therapeutic resistance, clinical biomarkers, and targeting strategies. Med Res Rev. 2017 11; 37(6):1318-1349. Han L, Xu J, Xu Q, Zhang B, Lam EW, Sun Y. PMID: 28586517.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    52. ER stress and cancer: The FOXO forkhead transcription factor link. Mol Cell Endocrinol. 2018 02 15; 462(Pt B):67-81. Alasiri G, Fan LY, Zona S, Goldsbrough IG, Ke HL, Auner HW, Lam EW. PMID: 28572047.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    53. Dysfunction of the WT1-MEG3 signaling promotes AML leukemogenesis via p53-dependent and -independent pathways. Leukemia. 2017 12; 31(12):2543-2551. Lyu Y, Lou J, Yang Y, Feng J, Hao Y, Huang S, Yin L, Xu J, Huang D, Ma B, Zou D, Wang Y, Zhang Y, Zhang B, Chen P, Yu K, Lam EW, Wang X, Liu Q, Yan J, Jin B. PMID: 28400619.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    54. Metabolomic characterisation of the effects of oncogenic PIK3CA transformation in a breast epithelial cell line. Sci Rep. 2017 04 10; 7:46079. Lau CE, Tredwell GD, Ellis JK, Lam EW, Keun HC. PMID: 28393905.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    55. When trainees reach competency in performing endoscopic ultrasound: a systematic review. Endosc Int Open. 2017 Apr; 5(4):E239-E243. Shahidi N, Ou G, Lam E, Enns R, Telford J. PMID: 28367496.
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    56. Multifaceted link between metabolism and cancer. Mol Cell Endocrinol. 2018 02 15; 462(Pt B):65-66. Saavedra-García P, Fan LY, Lam EW. PMID: 28351646.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    57. Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer. Breast Cancer Res Treat. 2017 Jun; 163(3):461-474. Asaduzzaman M, Constantinou S, Min H, Gallon J, Lin ML, Singh P, Raguz S, Ali S, Shousha S, Coombes RC, Lam EW, Hu Y, Yagüe E. PMID: 28341962.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    58. Dataset of the human homologues and orthologues of lipid-metabolic genes identified as DAF-16 targets their roles in lipid and energy metabolism. Data Brief. 2017 Apr; 11:606-610. Fan LY, Saavedra-García P, Lam EW. PMID: 28349111.
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    59. Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis. Oncogenesis. 2017 Feb 20; 6(2):e298. Kamran M, Long ZJ, Xu D, Lv SS, Liu B, Wang CL, Xu J, Lam EW, Liu Q. PMID: 28218735.
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    60. Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket. J Med Chem. 2017 03 09; 60(5):1928-1945. Sundriyal S, Moniot S, Mahmud Z, Yao S, Di Fruscia P, Reynolds CR, Dexter DT, Sternberg MJ, Lam EW, Steegborn C, Fuchter MJ. PMID: 28135086.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    61. FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells. Oncogene. 2017 06 15; 36(24):3428-3440. Yang N, Wang C, Wang Z, Zona S, Lin SX, Wang X, Yan M, Zheng FM, Li SS, Xu B, Bella L, Yong JS, Lam EW, Liu Q. PMID: 28114286.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    62. H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance. Cell Death Dis. 2017 01 19; 8(1):e2569. Peng F, Li TT, Wang KL, Xiao GQ, Wang JH, Zhao HD, Kang ZJ, Fan WJ, Zhu LL, Li M, Cui B, Zheng FM, Wang HJ, Lam EW, Wang B, Xu J, Liu Q. PMID: 28102845.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    63. Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis. Mol Cell Endocrinol. 2018 02 15; 462(Pt B):82-92. Saavedra-García P, Nichols K, Mahmud Z, Fan LY, Lam EW. PMID: 28087388.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    64. FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer. Br J Cancer. 2016 Nov 08; 115(10):1223-1233. Marzi L, Combes E, Vié N, Ayrolles-Torro A, Tosi D, Desigaud D, Perez-Gracia E, Larbouret C, Montagut C, Iglesias M, Jarlier M, Denis V, Linares LK, Lam EW, Martineau P, Del Rio M, Gongora C. PMID: 27685445.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    65. Repeat Endoscopic Ultrasound-Guided Fine-Needle Aspiration in Patients with Suspected Pancreatic Cancer: Diagnostic Yield and Associated Change in Access to Appropriate Care. Can J Gastroenterol Hepatol. 2016; 2016:7678403. Mitchell RA, Stanger D, Shuster C, Telford J, Lam E, Enns R. PMID: 27648440.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    66. Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation. Autophagy. 2016 10 02; 12(10):1804-1816. Gómez-Puerto MC, Verhagen LP, Braat AK, Lam EW, Coffer PJ, Lorenowicz MJ. PMID: 27532863.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    67. RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatment. Oncogenesis. 2016 Aug 15; 5(8):e252. Kongsema M, Zona S, Karunarathna U, Cabrera E, Man EP, Yao S, Shibakawa A, Khoo US, Medema RH, Freire R, Lam EW. PMID: 27526106.
      View in: PubMed   Mentions:
    68. 11a-N-Tosyl-5-deoxi-pterocarpan, LQB-223, a novel compound with potent antineoplastic activity toward breast cancer cells with different phenotypes. J Cancer Res Clin Oncol. 2016 Oct; 142(10):2119-30. Lemos LG, Nestal de Moraes G, Delbue D, Vasconcelos Fda C, Bernardo PS, Lam EW, Buarque CD, Costa PR, Maia RC. PMID: 27520309.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    69. Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy. Med Res Rev. 2016 11; 36(6):1036-1079. Yan M, Wang C, He B, Yang M, Tong M, Long Z, Liu B, Peng F, Xu L, Zhang Y, Liang D, Lei H, Subrata S, Kelley KW, Lam EW, Jin B, Liu Q. PMID: 27406026.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    70. p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA. Oncogene. 2017 01 19; 36(3):304-317. Xu LZ, Li SS, Zhou W, Kang ZJ, Zhang QX, Kamran M, Xu J, Liang DP, Wang CL, Hou ZJ, Wan XB, Wang HJ, Lam EW, Zhao ZW, Liu Q. PMID: 27345399.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    71. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016 07 01; 90(13):5915-27. Anghelina D, Lam E, Falck-Pedersen E. PMID: 27076643.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    72. FOXD3 controls pluripotency through modulating enhancer activity. Stem Cell Investig. 2016; 3:17. Yong JS, Intriago-Baldeón DP, Lam EW. PMID: 27488581.
      View in: PubMed   Mentions:
    73. Exogenous FABP4 increases breast cancer cell proliferation and activates the expression of fatty acid transport proteins. Mol Carcinog. 2017 01; 56(1):208-217. Guaita-Esteruelas S, Bosquet A, Saavedra P, Gumà J, Girona J, Lam EW, Amillano K, Borràs J, Masana L. PMID: 27061264.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    74. BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer. Oncogenesis. 2016 Apr 04; 5:e214. Gong C, Yao S, Gomes AR, Man EP, Lee HJ, Gong G, Chang S, Kim SB, Fujino K, Kim SW, Park SK, Lee JW, Lee MH, Khoo US, Lam EW. PMID: 27043660.
      View in: PubMed   Mentions:
    75. Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype. Nat Commun. 2016 Jan 19; 7:10180. Zheng F, Yue C, Li G, He B, Cheng W, Wang X, Yan M, Long Z, Qiu W, Yuan Z, Xu J, Liu B, Shi Q, Lam EW, Hung MC, Liu Q. PMID: 26782714.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    76. In Vitro Methods for Studying the Mechanisms of Resistance to DNA-Damaging Therapeutic Drugs. Methods Mol Biol. 2016; 1395:39-53. Khongkow P, Middleton AW, Middleton AK, Wong JP, Kandola NK, Kongsema M, de Moraes GN, Gomes AR, Lam EW. PMID: 26910067.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    77. Sirtuin1 (SIRT1) in the Acetylation of Downstream Target Proteins. Methods Mol Biol. 2016; 1436:169-88. Gomes AR, Yong JS, Kiew KC, Aydin E, Khongkow M, Laohasinnarong S, Lam EW. PMID: 27246215.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    78. Erratum to: In Vitro Methods for Studying the Mechanisms of Resistance to DNA-Damaging Therapeutic Drugs. Methods Mol Biol. 2016; 1395:E1. Khongkow P, Middleton AW, Wong JP, Kandola NK, Kongsema M, de Moraes GN, Gomes AR, Lam EW. PMID: 27488409.
      View in: PubMed   Mentions:    Fields:    
    79. Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance. Curr Drug Targets. 2016; 17(2):164-77. Nestal de Moraes G, Bella L, Zona S, Burton MJ, Lam EW. PMID: 25418858.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    80. Loss of Endometrial Plasticity in Recurrent Pregnancy Loss. Stem Cells. 2016 Feb; 34(2):346-56. Lucas ES, Dyer NP, Murakami K, Lee YH, Chan YW, Grimaldi G, Muter J, Brighton PJ, Moore JD, Patel G, Chan JK, Takeda S, Lam EW, Quenby S, Ott S, Brosens JJ. PMID: 26418742.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    81. STAT3:FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment. Tumour Biol. 2016 Apr; 37(4):5385-95. Silva LS, Goncalves LG, Silva F, Domingues G, Maximo V, Ferreira J, Lam EW, Dias S, Felix A, Serpa J. PMID: 26563366.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    82. FOXM1 targets XIAP and Survivin to modulate breast cancer survival and chemoresistance. Cell Signal. 2015 Dec; 27(12):2496-505. Nestal de Moraes G, Delbue D, Silva KL, Robaina MC, Khongkow P, Gomes AR, Zona S, Crocamo S, Mencalha AL, Magalhães LM, Lam EW, Maia RC. PMID: 26404623.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    83. FOXO3a and Posttranslational Modifications Mediate Glucocorticoid Sensitivity in B-ALL. Mol Cancer Res. 2015 Dec; 13(12):1578-90. Consolaro F, Ghaem-Maghami S, Bortolozzi R, Zona S, Khongkow M, Basso G, Viola G, Lam EW. PMID: 26376801.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    84. The pioneer factor PBX1 is a novel driver of metastatic progression in ERa-positive breast cancer. Oncotarget. 2015 Sep 08; 6(26):21878-91. Magnani L, Patten DK, Nguyen VT, Hong SP, Steel JH, Patel N, Lombardo Y, Faronato M, Gomes AR, Woodley L, Page K, Guttery D, Primrose L, Fernandez Garcia D, Shaw J, Viola P, Green A, Nolan C, Ellis IO, Rakha EA, Shousha S, Lam EW, Gyorffy B, Lupien M, Coombes RC. PMID: 26215677.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    85. Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer. Oncogenesis. 2015 Sep 07; 4:e167. Nestal de Moraes G, Khongkow P, Gong C, Yao S, Gomes AR, Ji Z, Kandola N, Delbue D, Man EP, Khoo US, Sharrocks AD, Lam EW. PMID: 26344694.
      View in: PubMed   Mentions:
    86. FOXM1 is overexpressed in B-acute lymphoblastic leukemia (B-ALL) and its inhibition sensitizes B-ALL cells to chemotherapeutic drugs. Int J Oncol. 2015 Oct; 47(4):1230-40. Consolaro F, Basso G, Ghaem-Magami S, Lam EW, Viola G. PMID: 26316295.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    87. Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727. Mol Immunol. 2015 Oct; 67(2 Pt B):317-24. Lam E, Choi SH, Pareek TK, Kim BG, Letterio JJ. PMID: 26198700.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    88. OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance. Oncogene. 2016 Mar 17; 35(11):1433-44. Karunarathna U, Kongsema M, Zona S, Gong C, Cabrera E, Gomes AR, Man EP, Khongkow P, Tsang JW, Khoo US, Medema RH, Freire R, Lam EW. PMID: 26148240.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    89. Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance. Oncogene. 2016 Feb 25; 35(8):990-1002. Khongkow P, Gomes AR, Gong C, Man EP, Tsang JW, Zhao F, Monteiro LJ, Coombes RC, Medema RH, Khoo US, Lam EW. PMID: 25961928.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    90. The clock protein period 2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells. FASEB J. 2015 Apr; 29(4):1603-14. Muter J, Lucas ES, Chan YW, Brighton PJ, Moore JD, Lacey L, Quenby S, Lam EW, Brosens JJ. PMID: 25573754.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    91. Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex. Cell Cycle. 2015; 14(8):1327-36. Lam E, Pareek TK, Letterio JJ. PMID: 25785643.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    92. FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer. Oncogene. 2015 Sep 24; 34(39):5012-24. Gong C, Fujino K, Monteiro LJ, Gomes AR, Drost R, Davidson-Smith H, Takeda S, Khoo US, Jonkers J, Sproul D, Lam EW. PMID: 25531315.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    93. Overexpression of forkhead box protein M1 (FOXM1) in ovarian cancer correlates with poor patient survival and contributes to paclitaxel resistance. PLoS One. 2014; 9(11):e113478. Zhao F, Siu MK, Jiang L, Tam KF, Ngan HY, Le XF, Wong OG, Wong ES, Gomes AR, Bella L, Khongkow P, Lam EW, Cheung AN. PMID: 25411964.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    94. The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model. ChemMedChem. 2015 Jan; 10(1):69-82. Di Fruscia P, Zacharioudakis E, Liu C, Moniot S, Laohasinnarong S, Khongkow M, Harrison IF, Koltsida K, Reynolds CR, Schmidtkunz K, Jung M, Chapman KL, Steegborn C, Dexter DT, Sternberg MJ, Lam EW, Fuchter MJ. PMID: 25395356.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    95. Forkhead box transcription factors in cancer initiation, progression and chemotherapeutic drug response. Front Oncol. 2014; 4:305. Lam EW, Gomes AR. PMID: 25401090.
      View in: PubMed   Mentions:
    96. Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells. J Virol. 2014 Dec; 88(24):14426-39. Lam E, Falck-Pedersen E. PMID: 25297994.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    97. FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance. Biochim Biophys Acta. 2014 Nov; 1839(11):1316-22. Zona S, Bella L, Burton MJ, Nestal de Moraes G, Lam EW. PMID: 25287128.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimals
    98. The pterocarpanquinone LQB-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets FoxO3a and FoxM1 transcription factors. Int J Oncol. 2014 Nov; 45(5):1949-58. Nestal de Moraes G, Castro CP, Salustiano EJ, Dumas ML, Costas F, Lam EW, Costa PR, Maia RC. PMID: 25174716.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    99. Assessment, validation and deployment strategy of a two-barcode protocol for facile genotyping of duckweed species. Plant Biol (Stuttg). 2015 Jan; 17 Suppl 1:42-9. Borisjuk N, Chu P, Gutierrez R, Zhang H, Acosta K, Friesen N, Sree KS, Garcia C, Appenroth KJ, Lam E. PMID: 25115915.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    100. FOXM1: A key oncofoetal transcription factor in health and disease. Semin Cancer Biol. 2014 Dec; 29:32-9. Bella L, Zona S, Nestal de Moraes G, Lam EW. PMID: 25068996.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    101. Cellular senescence and aging: the role of B-MYB. Aging Cell. 2014 Oct; 13(5):773-9. Mowla SN, Lam EW, Jat PS. PMID: 24981831.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    102. The chromatin landscape of the moss Physcomitrella patens and its dynamics during development and drought stress. Plant J. 2014 Jul; 79(1):67-81. Widiez T, Symeonidi A, Luo C, Lam E, Lawton M, Rensing SA. PMID: 24779858.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    103. A novel small molecule aurora kinase inhibitor attenuates breast tumor-initiating cells and overcomes drug resistance. Mol Cancer Ther. 2014 Aug; 13(8):1991-2003. Zheng FM, Long ZJ, Hou ZJ, Luo Y, Xu LZ, Xia JL, Lai XJ, Liu JW, Wang X, Kamran M, Yan M, Shao SJ, Lam EW, Wang SW, Lu G, Liu Q. PMID: 24899685.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    104. Expression profiling and significance of VEGF-A, VEGFR2, VEGFR3 and related proteins in endometrial carcinoma. Cytokine. 2014 Aug; 68(2):94-100. Wang J, Taylor A, Showeil R, Trivedi P, Horimoto Y, Bagwan I, Ewington L, Lam EW, El-Bahrawy MA. PMID: 24845798.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    105. IKKa restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation. Nat Commun. 2014 Apr 17; 5:3661. Yan M, Zhang Y, He B, Xiang J, Wang ZF, Zheng FM, Xu J, Chen MY, Zhu YL, Wen HJ, Wan XB, Yue CF, Yang N, Zhang W, Zhang JL, Wang J, Wang Y, Li LH, Zeng YX, Lam EW, Hung MC, Liu Q. PMID: 24739462.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    106. A randomized controlled trial assessing the effect of prescribed patient position changes during colonoscope withdrawal on adenoma detection. Gastrointest Endosc. 2014 Aug; 80(2):277-83. Ou G, Kim E, Lakzadeh P, Tong J, Enns R, Ramji A, Whittaker S, Ko HH, Bressler B, Halparin L, Lam E, Amar J, Telford J. PMID: 24629419.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    107. Quantitatively profiling genome-wide patterns of histone modifications in Arabidopsis thaliana using ChIP-seq. Methods Mol Biol. 2014; 1112:177-93. Luo C, Lam E. PMID: 24478015.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    108. SUMOylation inhibits FOXM1 activity and delays mitotic transition. Oncogene. 2014 Aug 21; 33(34):4316-29. Myatt SS, Kongsema M, Man CW, Kelly DJ, Gomes AR, Khongkow P, Karunarathna U, Zona S, Langer JK, Dunsby CW, Coombes RC, French PM, Brosens JJ, Lam EW. PMID: 24362530.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    109. Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade. J Virol. 2014 Jan; 88(2):974-81. Lam E, Stein S, Falck-Pedersen E. PMID: 24198409.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    110. 2 L versus 4 L of PEG3350 + electrolytes for outpatient colonic preparation: a randomized, controlled trial. Gastrointest Endosc. 2014 Mar; 79(3):408-416.e4. Brahmania M, Ou G, Bressler B, Ko HK, Lam E, Telford J, Enns R. PMID: 24206747.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    111. FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance. Oncogene. 2014 Aug 07; 33(32):4144-55. Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes AR, Yagüe E, Monteiro LJ, Kongsema M, Zona S, Man EP, Tsang JW, Coombes RC, Wu KJ, Khoo US, Medema RH, Freire R, Lam EW. PMID: 24141789.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    112. The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress. Oncogene. 2014 Jun 12; 33(24):3183-94. Lin A, Yao J, Zhuang L, Wang D, Han J, Lam EW, Gan B. PMID: 23851496.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    113. FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis. Cell Death Differ. 2013 Sep; 20(9):1219-29. van Boxtel R, Gomez-Puerto C, Mokry M, Eijkelenboom A, van der Vos KE, Nieuwenhuis EE, Burgering BM, Lam EW, Coffer PJ. PMID: 23832113.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    114. Forkhead box proteins: tuning forks for transcriptional harmony. Nat Rev Cancer. 2013 Jul; 13(7):482-95. Lam EW, Brosens JJ, Gomes AR, Koo CY. PMID: 23792361.
      View in: PubMed   Mentions: 154     Fields:    Translation:Humans
    115. Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and drug resistance. Chin J Cancer. 2013 Jul; 32(7):365-70. Gomes AR, Zhao F, Lam EW. PMID: 23706767.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    116. Progesterone and FOXO1 signaling: harnessing cellular senescence for the treatment of ovarian cancer. Cell Cycle. 2013 Jun 01; 12(11):1660-1. Brosens JJ, Lam EW. PMID: 23708447.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    117. An open-label study of lapatinib in women with HER-2-negative early breast cancer: the lapatinib pre-surgical study (LPS study). Ann Oncol. 2013 Apr; 24(4):924-30. Coombes RC, Tat T, Miller ML, Reise JA, Mansi JL, Hadjiminas DJ, Shousha S, Elsheikh SE, Lam EW, Horimoto Y, El-Bahrawy M, Aboagye EO, Contractor KB, Shaw JA, Walker RA, Marconell MH, Palmieri C, Stebbing J. PMID: 23233650.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    118. Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance. Front Med. 2012 Dec; 6(4):376-80. Zhao F, Lam EW. PMID: 23124885.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    119. The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment. Oncogene. 2013 Sep 26; 32(39):4634-45. Monteiro LJ, Khongkow P, Kongsema M, Morris JR, Man C, Weekes D, Koo CY, Gomes AR, Pinto PH, Varghese V, Kenny LM, Charles Coombes R, Freire R, Medema RH, Lam EW. PMID: 23108394.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    120. Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response. J Virol. 2012 Dec; 86(24):13303-12. Stein SC, Lam E, Falck-Pedersen E. PMID: 23015711.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    121. Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers. Oncogene. 2013 Jul 25; 32(30):3500-9. Siu MK, Wong ES, Kong DS, Chan HY, Jiang L, Wong OG, Lam EW, Chan KK, Ngan HY, Le XF, Cheung AN. PMID: 22945654.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    122. A specific role for phosphoinositide 3-kinase and AKT in osteoblasts? Front Endocrinol (Lausanne). 2012; 3:88. McGonnell IM, Grigoriadis AE, Lam EW, Price JS, Sunters A. PMID: 22833734.
      View in: PubMed   Mentions:
    123. The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment. Mol Cancer Res. 2012 Sep; 10(9):1189-202. de Olano N, Koo CY, Monteiro LJ, Pinto PH, Gomes AR, Aligue R, Lam EW. PMID: 22802261.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    124. Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters. Nucleic Acids Res. 2012 Sep; 40(16):7776-87. Barros P, Lam EW, Jordan P, Matos P. PMID: 22723377.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    125. Regulating the reapers: activating metacaspases for programmed cell death. Trends Plant Sci. 2012 Aug; 17(8):487-94. Lam E, Zhang Y. PMID: 22658651.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    126. The expression of interleukin-8 and interleukin-8 receptors in endometrial carcinoma. Cytokine. 2012 Aug; 59(2):417-22. Ewington L, Taylor A, Sriraksa R, Horimoto Y, Lam EW, El-Bahrawy MA. PMID: 22626766.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    127. Binding of FoxM1 to G2/M gene promoters is dependent upon B-Myb. Biochim Biophys Acta. 2012 Aug; 1819(8):855-62. Down CF, Millour J, Lam EW, Watson RJ. PMID: 22513242.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    128. A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis, and survival. J Immunol. 2012 Apr 15; 188(8):3920-7. Choi O, Heathcote DA, Ho KK, Müller PJ, Ghani H, Lam EW, Ashton-Rickardt PG, Rutschmann S. PMID: 22407915.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    129. Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury. J Neurosci. 2012 Mar 07; 32(10):3333-8. Huang C, Han X, Li X, Lam E, Peng W, Lou N, Torres A, Yang M, Garre JM, Tian GF, Bennett MV, Nedergaard M, Takano T. PMID: 22399755.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    130. The Discovery of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine SIRT2 Inhibitors. Medchemcomm. 2012 Mar 01; (3). Di Fruscia P, Ho KK, Laohasinnarong S, Khongkow M, Kroll SH, Islam SA, Sternberg MJ, Schmidtkunz K, Jung M, Lam EW, Fuchter MJ. PMID: 24340169.
      View in: PubMed   Mentions:
    131. Duckweed rising at Chengdu: summary of the 1st International Conference on Duckweed Application and Research. Plant Mol Biol. 2012 Apr; 78(6):627-32. Zhao H, Appenroth K, Landesman L, Salmeán AA, Lam E. PMID: 22318677.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsPHPublic Health
    132. The OPCML tumor suppressor functions as a cell surface repressor-adaptor, negatively regulating receptor tyrosine kinases in epithelial ovarian cancer. Cancer Discov. 2012 Feb; 2(2):156-71. McKie AB, Vaughan S, Zanini E, Okon IS, Louis L, de Sousa C, Greene MI, Wang Q, Agarwal R, Shaposhnikov D, Wong JL, Gungor H, Janczar S, El-Bahrawy M, Lam EW, Chayen NE, Gabra H. PMID: 22585860.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    133. The transcription factor encyclopedia. Genome Biol. 2012; 13(3):R24. Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW. PMID: 22458515.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    134. Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin. J Biol Chem. 2012 Jan 06; 287(2):1545-55. Ho KK, McGuire VA, Koo CY, Muir KW, de Olano N, Maifoshie E, Kelly DJ, McGovern UB, Monteiro LJ, Gomes AR, Nebreda AR, Campbell DG, Arthur JS, Lam EW. PMID: 22128155.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    135. Mechanisms of endometrial progesterone resistance. Mol Cell Endocrinol. 2012 Jul 25; 358(2):208-15. Al-Sabbagh M, Lam EW, Brosens JJ. PMID: 22085558.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    136. FOXM1: From cancer initiation to progression and treatment. Biochim Biophys Acta. 2012 Jan; 1819(1):28-37. Koo CY, Muir KW, Lam EW. PMID: 21978825.
      View in: PubMed   Mentions: 130     Fields:    Translation:Humans
    137. iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe. Clin Cancer Res. 2011 Nov 01; 17(21):6924-33. Jiang L, Siu MK, Wong OG, Tam KF, Lu X, Lam EW, Ngan HY, Le XF, Wong ES, Monteiro LJ, Chan HY, Cheung AN. PMID: 21926165.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    138. FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer. Oncogene. 2012 Apr 05; 31(14):1845-58. Karadedou CT, Gomes AR, Chen J, Petkovic M, Ho KK, Zwolinska AK, Feltes A, Wong SY, Chan KY, Cheung YN, Tsang JW, Brosens JJ, Khoo US, Lam EW. PMID: 21860419.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    139. FOXO and FOXM1 in cancer: the FOXO-FOXM1 axis shapes the outcome of cancer chemotherapy. Curr Drug Targets. 2011 Aug; 12(9):1256-66. Wilson MS, Brosens JJ, Schwenen HD, Lam EW. PMID: 21443467.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    140. FOXO transcription factors and their role in disorders of the female reproductive tract. Curr Drug Targets. 2011 Aug; 12(9):1291-302. Christian M, Lam EW, Wilson MS, Brosens JJ. PMID: 21443468.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    141. ERß1 represses FOXM1 expression through targeting ERa to control cell proliferation in breast cancer. Am J Pathol. 2011 Sep; 179(3):1148-56. Horimoto Y, Hartman J, Millour J, Pollock S, Olmos Y, Ho KK, Coombes RC, Poutanen M, Mäkelä SI, El-Bahrawy M, Speirs V, Lam EW. PMID: 21763263.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    142. Review: lapatinib in metastatic colorectal cancer-another strategy for disease control? Clin Adv Hematol Oncol. 2011 Jun; 9(6):500-1. Kenny LM, Lam EW. PMID: 21841752.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    143. Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressor. Cell Death Differ. 2011 Aug; 18(8):1271-8. Ishikawa T, Watanabe N, Nagano M, Kawai-Yamada M, Lam E. PMID: 21597463.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    144. Arabidopsis metacaspase 2d is a positive mediator of cell death induced during biotic and abiotic stresses. Plant J. 2011 Jun; 66(6):969-82. Watanabe N, Lam E. PMID: 21395887.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    145. ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance. Mol Cancer Ther. 2011 Jun; 10(6):1046-58. Millour J, de Olano N, Horimoto Y, Monteiro LJ, Langer JK, Aligue R, Hajji N, Lam EW. PMID: 21518729.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    146. Rapid temporal control of Foxp3 protein degradation by sirtuin-1. PLoS One. 2011 Apr 20; 6(4):e19047. van Loosdregt J, Brunen D, Fleskens V, Pals CE, Lam EW, Coffer PJ. PMID: 21533107.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    147. The diversity of sex steroid action: the role of micro-RNAs and FOXO transcription factors in cycling endometrium and cancer. J Endocrinol. 2012 Jan; 212(1):13-25. Lam EW, Shah K, Brosens JJ. PMID: 21382987.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    148. FLIM FRET technology for drug discovery: automated multiwell-plate high-content analysis, multiplexed readouts and application in situ. Chemphyschem. 2011 Feb 25; 12(3):609-26. Kumar S, Alibhai D, Margineanu A, Laine R, Kennedy G, McGinty J, Warren S, Kelly D, Alexandrov Y, Munro I, Talbot C, Stuckey DW, Kimberly C, Viellerobe B, Lacombe F, Lam EW, Taylor H, Dallman MJ, Stamp G, Murray EJ, Stuhmeier F, Sardini A, Katan M, Elson DS, Neil MA, Dunsby C, French PM. PMID: 21337485.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    149. Calcium-dependent activation and autolysis of Arabidopsis metacaspase 2d. J Biol Chem. 2011 Mar 25; 286(12):10027-40. Watanabe N, Lam E. PMID: 21209078.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    150. Chromatin beacons: global sampling of chromatin physical properties using chromatin charting lines. Methods Mol Biol. 2011; 701:301-14. Amini A, Luo C, Lam E. PMID: 21181538.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    151. Interplay between SIRT proteins and tumour suppressor transcription factors in chemotherapeutic resistance of cancer. Drug Resist Updat. 2011 Feb; 14(1):35-44. Olmos Y, Brosens JJ, Lam EW. PMID: 21195657.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    152. Overexpression of proto-oncogene FBI-1 activates membrane type 1-matrix metalloproteinase in association with adverse outcome in ovarian cancers. Mol Cancer. 2010 Dec 21; 9:318. Jiang L, Siu MK, Wong OG, Tam KF, Lam EW, Ngan HY, Le XF, Wong ES, Chan HY, Cheung AN. PMID: 21176152.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    153. NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling. Endocrinology. 2011 Feb; 152(2):730-40. Al-Sabbagh M, Fusi L, Higham J, Lee Y, Lei K, Hanyaloglu AC, Lam EW, Christian M, Brosens JJ. PMID: 21159852.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    154. Factors associated with incomplete small bowel capsule endoscopy studies. World J Gastroenterol. 2010 Nov 14; 16(42):5329-33. Lee MM, Jacques A, Lam E, Kwok R, Lakzadeh P, Sandhar A, Segal B, Svarta S, Law J, Enns R. PMID: 21072896.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    155. Sense and sensitivity: FOXO and ROS in cancer development and treatment. Antioxid Redox Signal. 2011 Feb 15; 14(4):675-87. Myatt SS, Brosens JJ, Lam EW. PMID: 20649462.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    156. Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis. J Exp Med. 2010 Oct 25; 207(11):2507-19. Pareek TK, Lam E, Zheng X, Askew D, Kulkarni AB, Chance MR, Huang AY, Cooke KR, Letterio JJ. PMID: 20937706.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    157. Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells. J Biol Chem. 2010 Dec 10; 285(50):39211-23. Serpa J, Caiado F, Carvalho T, Torre C, Gonçalves LG, Casalou C, Lamosa P, Rodrigues M, Zhu Z, Lam EW, Dias S. PMID: 20926374.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    158. Sustained spindle-assembly checkpoint response requires de novo transcription and translation of cyclin B1. PLoS One. 2010 Sep 28; 5(9). Mena AL, Lam EW, Chatterjee S. PMID: 20927403.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    159. Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. PLoS One. 2010 Aug 20; 5(8):e12293. Chen J, Gomes AR, Monteiro LJ, Wong SY, Wu LH, Ng TT, Karadedou CT, Millour J, Ip YC, Cheung YN, Sunters A, Chan KY, Lam EW, Khoo US. PMID: 20808831.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    160. The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain. J Biol Chem. 2010 Oct 01; 285(40):30837-50. Ferrari-Amorotti G, Mariani SA, Novi C, Cattelani S, Pecorari L, Corradini F, Soliera AR, Manzotti G, Fragliasso V, Zhang Y, Martinez RV, Lam EW, Guerzoni C, Calabretta B. PMID: 20659895.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    161. Lymphoepithelial cysts of the pancreas: the use of endoscopic ultrasound-guided fine-needle aspiration in diagnosis. Can J Gastroenterol. 2010 Jun; 24(6):348-50. Karim Z, Walker B, Lam E. PMID: 20559575.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    162. Contact-printed microelectromechanical systems. Adv Mater. 2010 Apr 22; 22(16):1840-4. Packard CE, Murarka A, Lam EW, Schmidt MA, Bulovic V. PMID: 20512958.
      View in: PubMed   Mentions: 1     Fields:    
    163. SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2. Mol Cancer Ther. 2010 Apr; 9(4):844-55. Peck B, Chen CY, Ho KK, Di Fruscia P, Myatt SS, Coombes RC, Fuchter MJ, Hsiao CD, Lam EW. PMID: 20371709.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCells
    164. Endoscopic mucosal resection: early experience in British Columbia. Can J Gastroenterol. 2010 Apr; 24(4):239-44. Brahmania M, Lam E, Telford J, Enns R. PMID: 20431812.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    165. FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance. Oncogene. 2010 May 20; 29(20):2983-95. Millour J, Constantinidou D, Stavropoulou AV, Wilson MS, Myatt SS, Kwok JM, Sivanandan K, Coombes RC, Medema RH, Hartman J, Lykkesfeldt AE, Lam EW. PMID: 20208560.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    166. Bone marrow mesenchymal stromal cells non-selectively protect chronic myeloid leukemia cells from imatinib-induced apoptosis via the CXCR4/CXCL12 axis. Haematologica. 2010 Jul; 95(7):1081-9. Vianello F, Villanova F, Tisato V, Lymperi S, Ho KK, Gomes AR, Marin D, Bonnet D, Apperley J, Lam EW, Dazzi F. PMID: 20179085.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    167. The human papillomavirus type 16 E5 oncoprotein synergizes with EGF-receptor signaling to enhance cell cycle progression and the down-regulation of p27(Kip1). Virology. 2010 Apr 25; 400(1):44-52. Pedroza-Saavedra A, Lam EW, Esquivel-Guadarrama F, Gutierrez-Xicotencatl L. PMID: 20144468.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    168. FOXM1 confers acquired cisplatin resistance in breast cancer cells. Mol Cancer Res. 2010 Jan; 8(1):24-34. Kwok JM, Peck B, Monteiro LJ, Schwenen HD, Millour J, Coombes RC, Myatt SS, Lam EW. PMID: 20068070.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    169. Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer. Cancer Res. 2010 Jan 01; 70(1):367-77. Myatt SS, Wang J, Monteiro LJ, Christian M, Ho KK, Fusi L, Dina RE, Brosens JJ, Ghaem-Maghami S, Lam EW. PMID: 20028871.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    170. Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals. FASEB J. 2010 May; 24(5):1541-51. Leitao B, Jones MC, Fusi L, Higham J, Lee Y, Takano M, Goto T, Christian M, Lam EW, Brosens JJ. PMID: 20026682.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    171. The expression of IL-8 and IL-8 receptors in pancreatic adenocarcinomas and pancreatic neuroendocrine tumours. Cytokine. 2010 Feb; 49(2):134-40. Hussain F, Wang J, Ahmed R, Guest SK, Lam EW, Stamp G, El-Bahrawy M. PMID: 20005738.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    172. Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferation. Breast Cancer Res. 2009; 11(6):R79. Hartman J, Lam EW, Gustafsson JA, Ström A. PMID: 19891787.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    173. Bax Inhibitor-1, a conserved cell death suppressor, is a key molecular switch downstream from a variety of biotic and abiotic stress signals in plants. Int J Mol Sci. 2009 Jul 10; 10(7):3149-67. Watanabe N, Lam E. PMID: 19742129.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    174. FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer. Int J Oncol. 2009 Jul; 35(1):57-68. Francis RE, Myatt SS, Krol J, Hartman J, Peck B, McGovern UB, Wang J, Guest SK, Filipovic A, Gojis O, Palmieri C, Peston D, Shousha S, Yu Q, Sicinski P, Coombes RC, Lam EW. PMID: 19513552.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    175. Add-on cases in the endoscopy unit: Factors that affect volume. Can J Gastroenterol. 2009 Jul; 23(7):485-8. Segal B, Lam E, Amar J, Bressler B, Halparin L, Ramji A, Telford J, Whittaker S, Enns R. PMID: 19623331.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    176. Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours. Breast Cancer Res. 2009; 11(3):R40. Albergaria A, Paredes J, Sousa B, Milanezi F, Carneiro V, Bastos J, Costa S, Vieira D, Lopes N, Lam EW, Lunet N, Schmitt F. PMID: 19549328.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    177. The novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells. FEBS J. 2009 Aug; 276(15):4037-50. Ho KK, Rosivatz E, Gunn RM, Smith ME, Stavropoulou AV, Rosivatz E, Numbere MG, Wong JB, Lafitte VG, Behrendt JM, Myatt SS, Hailes HC, Woscholski R, Lam EW. PMID: 19549188.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    178. Defining the functional network of epigenetic regulators in Arabidopsis thaliana. Mol Plant. 2009 Jul; 2(4):661-674. Luo C, Durgin BG, Watanabe N, Lam E. PMID: 19825647.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    179. Charting functional and physical properties of chromatin in living cells. Curr Opin Genet Dev. 2009 Apr; 19(2):135-41. Lam E, Luo C, Watanabe N. PMID: 19327981.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    180. Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer. Mol Cancer Ther. 2009 Mar; 8(3):582-91. McGovern UB, Francis RE, Peck B, Guest SK, Wang J, Myatt SS, Krol J, Kwok JM, Polychronis A, Coombes RC, Lam EW. PMID: 19276163.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    181. CD40 and B-cell receptor signalling induce MAPK family members that can either induce or repress Bcl-6 expression. Mol Immunol. 2009 May; 46(8-9):1727-35. Batlle A, Papadopoulou V, Gomes AR, Willimott S, Melo JV, Naresh K, Lam EW, Wagner SD. PMID: 19268365.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    182. Chromatin charting: global mapping of epigenetic effects. Methods Mol Biol. 2009; 553:127-39. Luo C, Lam E. PMID: 19588104.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    183. FOXO transcription factors: from cell fate decisions to regulation of human female reproduction. Adv Exp Med Biol. 2009; 665:227-41. Brosens JJ, Wilson MS, Lam EW. PMID: 20429428.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    184. Studying the subcellular localization and DNA-binding activity of FoxO transcription factors, downstream effectors of PI3K/Akt. Methods Mol Biol. 2009; 462:201-11. Essafi A, Gomes AR, Pomeranz KM, Zwolinska AK, Varshochi R, McGovern UB, Lam EW. PMID: 19160671.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    185. BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3. Blood. 2009 Mar 05; 113(10):2302-11. Nordigården A, Kraft M, Eliasson P, Labi V, Lam EW, Villunger A, Jönsson JI. PMID: 19064725.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    186. Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A. Oncogene. 2009 Feb 05; 28(5):721-33. Bertoli C, Copetti T, Lam EW, Demarchi F, Schneider C. PMID: 19029949.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    187. Resist or die: FOXO transcription factors determine the cellular response to chemotherapy. Cell Cycle. 2008 Oct; 7(20):3133-6. Gomes AR, Brosens JJ, Lam EW. PMID: 18927504.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    188. FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells. Mol Cancer Ther. 2008 Oct; 7(10):3237-46. Fernández de Mattos S, Villalonga P, Clardy J, Lam EW. PMID: 18852127.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    189. Arabidopsis Bax inhibitor-1: A rheostat for ER stress-induced programmed cell death. Plant Signal Behav. 2008 Aug; 3(8):564-6. Watanabe N, Lam E. PMID: 19704470.
      View in: PubMed   Mentions: 7     Fields:    
    190. The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression. Mol Cell Biol. 2008 Oct; 28(19):5886-98. Hui RC, Gomes AR, Constantinidou D, Costa JR, Karadedou CT, Fernandez de Mattos S, Wymann MP, Brosens JJ, Schulze A, Lam EW. PMID: 18644865.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    191. Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression. Mol Cancer Ther. 2008 Jul; 7(7):2022-32. Kwok JM, Myatt SS, Marson CM, Coombes RC, Constantinidou D, Lam EW. PMID: 18645012.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    192. The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium. Endocrinology. 2008 Sep; 149(9):4462-74. Cloke B, Huhtinen K, Fusi L, Kajihara T, Yliheikkilä M, Ho KK, Teklenburg G, Lavery S, Jones MC, Trew G, Kim JJ, Lam EW, Cartwright JE, Poutanen M, Brosens JJ. PMID: 18511503.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    193. FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression. J Biol Chem. 2008 Jun 13; 283(24):16545-53. Li SK, Smith DK, Leung WY, Cheung AM, Lam EW, Dimri GP, Yao KM. PMID: 18408007.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    194. Many forks in the path: cycling with FoxO. Oncogene. 2008 Apr 07; 27(16):2300-11. Ho KK, Myatt SS, Lam EW. PMID: 18391972.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimals
    195. Targeting FOXM1. Nat Rev Cancer. 2008 Mar; 8(3):242. Myatt SS, Lam EW. PMID: 18297052.
      View in: PubMed   Mentions: 26     Fields:    
    196. Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells. Mol Cancer Ther. 2008 Mar; 7(3):670-8. Hui RC, Francis RE, Guest SK, Costa JR, Gomes AR, Myatt SS, Brosens JJ, Lam EW. PMID: 18347152.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    197. Biliary brush cytology: factors associated with positive yields on biliary brush cytology. World J Gastroenterol. 2008 Jan 28; 14(4):569-73. Mahmoudi N, Enns R, Amar J, AlAli J, Lam E, Telford J. PMID: 18203289.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    198. Size and number of tandem repeat arrays can determine somatic homologous pairing of transgene loci mediated by epigenetic modifications in Arabidopsis thaliana nuclei. Chromosoma. 2008 Jun; 117(3):267-76. Jovtchev G, Watanabe K, Pecinka A, Rosin FM, Mette MF, Lam E, Schubert I. PMID: 18200447.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    199. Identification of cyclin A2 as the downstream effector of the nuclear phosphatidylinositol 4,5-bisphosphate signaling network. J Biol Chem. 2008 Feb 29; 283(9):5477-85. Ho KK, Anderson AA, Rosivatz E, Lam EW, Woscholski R, Mann DJ. PMID: 18077453.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    200. The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells. Mol Cancer Ther. 2007 Dec; 6(12 Pt 1):3169-79. Krol J, Francis RE, Albergaria A, Sunters A, Polychronis A, Coombes RC, Lam EW. PMID: 18089711.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    201. BAX inhibitor-1 modulates endoplasmic reticulum stress-mediated programmed cell death in Arabidopsis. J Biol Chem. 2008 Feb 08; 283(6):3200-10. Watanabe N, Lam E. PMID: 18039663.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    202. The emerging roles of forkhead box (Fox) proteins in cancer. Nat Rev Cancer. 2007 Nov; 7(11):847-59. Myatt SS, Lam EW. PMID: 17943136.
      View in: PubMed   Mentions: 374     Fields:    Translation:HumansAnimalsCells
    203. Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J. 2007 Oct 31; 26(21):4445-56. Qu X, Lam E, Doughman YQ, Chen Y, Chou YT, Lam M, Turakhia M, Dunwoodie SL, Watanabe M, Xu B, Duncan SA, Yang YC. PMID: 17932483.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    204. Functional regulation of D-type cyclins by insulin-like growth factor-I and serum in multiple myeloma cells. Br J Haematol. 2007 Oct; 139(2):243-54. Glassford J, Rabin N, Lam EW, Yong KL. PMID: 17897300.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    205. Role and regulation of the serum- and glucocorticoid-regulated kinase 1 in fertile and infertile human endometrium. Endocrinology. 2007 Oct; 148(10):5020-9. Feroze-Zaidi F, Fusi L, Takano M, Higham J, Salker MS, Goto T, Edassery S, Klingel K, Boini KM, Palmada M, Kamps R, Groothuis PG, Lam EW, Smith SK, Lang F, Sharkey AM, Brosens JJ. PMID: 17640988.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    206. Transcriptional cross talk between the forkhead transcription factor forkhead box O1A and the progesterone receptor coordinates cell cycle regulation and differentiation in human endometrial stromal cells. Mol Endocrinol. 2007 Oct; 21(10):2334-49. Takano M, Lu Z, Goto T, Fusi L, Higham J, Francis J, Withey A, Hardt J, Cloke B, Stavropoulou AV, Ishihara O, Lam EW, Unterman TG, Brosens JJ, Kim JJ. PMID: 17609436.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    207. Mechanism and functional consequences of loss of FOXO1 expression in endometrioid endometrial cancer cells. Oncogene. 2008 Jan 03; 27(1):9-19. Goto T, Takano M, Albergaria A, Briese J, Pomeranz KM, Cloke B, Fusi L, Feroze-Zaidi F, Maywald N, Sajin M, Dina RE, Ishihara O, Takeda S, Lam EW, Bamberger AM, Ghaem-Maghami S, Brosens JJ. PMID: 17599040.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    208. Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression. Mol Cell Biol. 2007 Jul; 27(13):4917-30. Delpuech O, Griffiths B, East P, Essafi A, Lam EW, Burgering B, Downward J, Schulze A. PMID: 17452451.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    209. Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells. Cancer Res. 2007 Apr 15; 67(8):3955-62. Zhao C, Matthews J, Tujague M, Wan J, Ström A, Toresson G, Lam EW, Cheng G, Gustafsson JA, Dahlman-Wright K. PMID: 17440111.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    210. Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesis. Cell Div. 2007 Feb 12; 2:6. Myatt SS, Lam EW. PMID: 17295909.
      View in: PubMed   Mentions:
    211. Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle. Transplantation. 2007 Jan 15; 83(1):71-6. Ramasamy R, Fazekasova H, Lam EW, Soeiro I, Lombardi G, Dazzi F. PMID: 17220794.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansCells
    212. A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN). ACS Chem Biol. 2006 Dec 15; 1(12):780-90. Rosivatz E, Matthews JG, McDonald NQ, Mulet X, Ho KK, Lossi N, Schmid AC, Mirabelli M, Pomeranz KM, Erneux C, Lam EW, Vilar R, Woscholski R. PMID: 17240976.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    213. Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth. Leukemia. 2007 Feb; 21(2):304-10. Ramasamy R, Lam EW, Soeiro I, Tisato V, Bonnet D, Dazzi F. PMID: 17170725.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    214. FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1. J Biol Chem. 2007 Jan 26; 282(4):2211-20. Birkenkamp KU, Essafi A, van der Vos KE, da Costa M, Hui RC, Holstege F, Koenderman L, Lam EW, Coffer PJ. PMID: 17132628.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    215. Latent protein LANA2 from Kaposi's sarcoma-associated herpesvirus interacts with 14-3-3 proteins and inhibits FOXO3a transcription factor. J Virol. 2007 Feb; 81(3):1511-6. Muñoz-Fontela C, Marcos-Villar L, Gallego P, Arroyo J, Da Costa M, Pomeranz KM, Lam EW, Rivas C. PMID: 17108038.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    216. Chronic protein kinase B (PKB/c-akt) activation leads to apoptosis induced by oxidative stress-mediated Foxo3a transcriptional up-regulation. Cancer Res. 2006 Nov 15; 66(22):10760-9. van Gorp AG, Pomeranz KM, Birkenkamp KU, Hui RC, Lam EW, Coffer PJ. PMID: 17108112.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    217. FOXO transcription factors: key regulators of cell fate. Biochem Soc Trans. 2006 Nov; 34(Pt 5):722-6. Lam EW, Francis RE, Petkovic M. PMID: 17052182.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    218. Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16272-7. Jones MC, Fusi L, Higham JH, Abdel-Hafiz H, Horwitz KB, Lam EW, Brosens JJ. PMID: 17053081.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    219. Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells. Mol Cancer. 2006 Oct 03; 5:40. Alao JP, Stavropoulou AV, Lam EW, Coombes RC. PMID: 17018141.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    220. Human homologs of the putative G protein-coupled membrane progestin receptors (mPRalpha, beta, and gamma) localize to the endoplasmic reticulum and are not activated by progesterone. Mol Endocrinol. 2006 Dec; 20(12):3146-64. Krietsch T, Fernandes MS, Kero J, Lösel R, Heyens M, Lam EW, Huhtaniemi I, Brosens JJ, Gellersen B. PMID: 16959873.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    221. Epstein-Barr virus represses the FoxO1 transcription factor through latent membrane protein 1 and latent membrane protein 2A. J Virol. 2006 Nov; 80(22):11191-9. Shore AM, White PC, Hui RC, Essafi A, Lam EW, Rowe M, Brennan P. PMID: 16943287.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    222. Expression of viral capsid protein antigen against Epstein-Barr virus in plastids of Nicotiana tabacum cv. SR1. Biotechnol Bioeng. 2006 Aug 20; 94(6):1129-37. Lee MY, Zhou Y, Lung RW, Chye ML, Yip WK, Zee SY, Lam E. PMID: 16586511.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    223. In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography. Cancer Res. 2006 Aug 01; 66(15):7621-9. Leyton J, Alao JP, Da Costa M, Stavropoulou AV, Latigo JR, Perumal M, Pillai R, He Q, Atadja P, Lam EW, Workman P, Vigushin DM, Aboagye EO. PMID: 16885362.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    224. p27Kip1 and p130 cooperate to regulate hematopoietic cell proliferation in vivo. Mol Cell Biol. 2006 Aug; 26(16):6170-84. Soeiro I, Mohamedali A, Romanska HM, Lea NC, Child ES, Glassford J, Orr SJ, Roberts C, Naresh KN, Lalani el-N, Mann DJ, Watson RJ, Thomas NS, Lam EW. PMID: 16880527.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    225. The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells. J Biol Chem. 2006 Sep 01; 281(35):25167-76. Madureira PA, Varshochi R, Constantinidou D, Francis RE, Coombes RC, Yao KM, Lam EW. PMID: 16809346.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    226. Differential expression of FOXO1 and FOXO3a confers resistance to oxidative cell death upon endometrial decidualization. Mol Endocrinol. 2006 Oct; 20(10):2444-55. Kajihara T, Jones M, Fusi L, Takano M, Feroze-Zaidi F, Pirianov G, Mehmet H, Ishihara O, Higham JM, Lam EW, Brosens JJ. PMID: 16709600.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    227. Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes. Oncogene. 2006 Apr 06; 25(15):2170-80. White PC, Shore AM, Clement M, McLaren J, Soeiro I, Lam EW, Brennan P. PMID: 16301994.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    228. Stimulation of human breast carcinoma cell invasiveness and urokinase plasminogen activator activity by glucose deprivation. Exp Cell Res. 2006 Jun 10; 312(10):1685-92. Belkacemi L, Lam E, Caldwell JD, Siemens DR, Graham CH. PMID: 16564525.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    229. Heparin prevents programmed cell death in human trophoblast. Mol Hum Reprod. 2006 Apr; 12(4):237-43. Hills FA, Abrahams VM, González-Timón B, Francis J, Cloke B, Hinkson L, Rai R, Mor G, Regan L, Sullivan M, Lam EW, Brosens JJ. PMID: 16556679.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    230. Arabidopsis Bax inhibitor-1 functions as an attenuator of biotic and abiotic types of cell death. Plant J. 2006 Mar; 45(6):884-94. Watanabe N, Lam E. PMID: 16507080.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    231. Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells. Mol Cancer. 2006 Feb 20; 5:8. Alao JP, Stavropoulou AV, Lam EW, Coombes RC, Vigushin DM. PMID: 16504004.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    232. The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines. Mol Cancer. 2006 Feb 17; 5:7. Alao JP, Gamble SC, Stavropoulou AV, Pomeranz KM, Lam EW, Coombes RC, Vigushin DM. PMID: 16503970.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    233. Inflammation and sex steroid receptors: a motif for change. Cell. 2006 Feb 10; 124(3):466-8. Brosens JJ, Lam EW, Parker MG. PMID: 16469693.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    234. A truncated hepatitis E virus ORF2 protein expressed in tobacco plastids is immunogenic in mice. World J Gastroenterol. 2006 Jan 14; 12(2):306-12. Zhou YX, Lee MY, Ng JM, Chye ML, Yip WK, Zee SY, Lam E. PMID: 16482635.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    235. Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt. Cancer Res. 2006 Jan 01; 66(1):212-20. Sunters A, Madureira PA, Pomeranz KM, Aubert M, Brosens JJ, Cook SJ, Burgering BM, Coombes RC, Lam EW. PMID: 16397234.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    236. DNA hypomethylation reduces homologous pairing of inserted tandem repeat arrays in somatic nuclei of Arabidopsis thaliana. Plant J. 2005 Nov; 44(4):531-40. Watanabe K, Pecinka A, Meister A, Schubert I, Lam E. PMID: 16262704.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    237. Regulated expression of putative membrane progestin receptor homologues in human endometrium and gestational tissues. J Endocrinol. 2005 Oct; 187(1):89-101. Fernandes MS, Pierron V, Michalovich D, Astle S, Thornton S, Peltoketo H, Lam EW, Gellersen B, Huhtaniemi I, Allen J, Brosens JJ. PMID: 16214944.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    238. Murine gamma-herpesvirus 68 latency protein M2 binds to Vav signaling proteins and inhibits B-cell receptor-induced cell cycle arrest and apoptosis in WEHI-231 B cells. J Biol Chem. 2005 Nov 11; 280(45):37310-8. Madureira PA, Matos P, Soeiro I, Dixon LK, Simas JP, Lam EW. PMID: 16150693.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    239. Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes. Eur J Immunol. 2005 Sep; 35(9):2748-61. Glassford J, Vigorito E, Soeiro I, Madureira PA, Zoumpoulidou G, Brosens JJ, Turner M, Lam EW. PMID: 16114097.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    240. Progestins regulate the expression and activity of the forkhead transcription factor FOXO1 in differentiating human endometrium. Mol Endocrinol. 2006 Jan; 20(1):35-44. Labied S, Kajihara T, Madureira PA, Fusi L, Jones MC, Higham JM, Varshochi R, Francis JM, Zoumpoulidou G, Essafi A, Fernandez de Mattos S, Lam EW, Brosens JJ. PMID: 16123151.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    241. Tandem repetitive transgenes and fluorescent chromatin tags alter local interphase chromosome arrangement in Arabidopsis thaliana. J Cell Sci. 2005 Aug 15; 118(Pt 16):3751-8. Pecinka A, Kato N, Meister A, Probst AV, Schubert I, Lam E. PMID: 16076901.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    242. Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells. Oncogene. 2005 Mar 31; 24(14):2317-29. Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW. PMID: 15688014.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    243. Quiescence and functional reprogramming of Epstein-Barr virus (EBV)-specific CD8+ T cells during persistent infection. Blood. 2005 Jul 15; 106(2):558-65. Dunne PJ, Belaramani L, Fletcher JM, Fernandez de Mattos S, Lawrenz M, Soares MV, Rustin MH, Lam EW, Salmon M, Akbar AN. PMID: 15797994.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    244. Inducible double-stranded RNA expression activates reversible transcript turnover and stable translational suppression of a target gene in transgenic tobacco. FEBS Lett. 2005 Feb 28; 579(6):1498-502. Lo C, Wang N, Lam E. PMID: 15733863.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    245. Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine-specific cysteine proteases and activate apoptosis-like cell death in yeast. J Biol Chem. 2005 Apr 15; 280(15):14691-9. Watanabe N, Lam E. PMID: 15691845.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    246. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood. 2005 Apr 01; 105(7):2821-7. Glennie S, Soeiro I, Dyson PJ, Lam EW, Dazzi F. PMID: 15591115.
      View in: PubMed   Mentions: 284     Fields:    Translation:AnimalsCells
    247. Tobacco-related-compound-induced nitrosative stress injury in the hamster cheek pouch. J Dent Res. 2004 Dec; 83(12):903-8. Barley RD, Pollock S, Shallow MC, Peters E, Lam EW. PMID: 15557395.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    248. Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines. Clin Cancer Res. 2004 Dec 01; 10(23):8094-104. Alao JP, Lam EW, Ali S, Buluwela L, Bordogna W, Lockey P, Varshochi R, Stavropoulou AV, Coombes RC, Vigushin DM. PMID: 15585645.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    249. Transgenic plant-derived siRNAs can suppress propagation of influenza virus in mammalian cells. FEBS Lett. 2004 Nov 19; 577(3):345-50. Zhou Y, Chan JH, Chan AY, Chak RK, Wong EY, Chye ML, Peiris JS, Poon LL, Lam E. PMID: 15556607.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    250. ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line. J Biol Chem. 2005 Feb 04; 280(5):3185-96. Varshochi R, Halim F, Sunters A, Alao JP, Madureira PA, Hart SM, Ali S, Vigushin DM, Coombes RC, Lam EW. PMID: 15557281.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    251. FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism. Mol Cell Biol. 2004 Nov; 24(22):10058-71. Fernández de Mattos S, Essafi A, Soeiro I, Pietersen AM, Birkenkamp KU, Edwards CS, Martino A, Nelson BH, Francis JM, Jones MC, Brosens JJ, Coffer PJ, Lam EW. PMID: 15509806.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    252. Vav-dependent and vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus. J Immunol. 2004 Sep 01; 173(5):3209-14. Vigorito E, Bardi G, Glassford J, Lam EW, Clayton E, Turner M. PMID: 15322182.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    253. The expression of oestrogen receptor (ER)-beta and its variants, but not ERalpha, in adult human mammary fibroblasts. J Mol Endocrinol. 2004 Aug; 33(1):35-50. Palmieri C, Saji S, Sakaguchi H, Cheng G, Sunters A, O'Hare MJ, Warner M, Gustafsson JA, Coombes RC, Lam EW. PMID: 15291741.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    254. Comparison of thoracic ultrasound, clinical acumen, and radiography in patients with minor chest injury. J Trauma. 2004 Jun; 56(6):1211-3. Rainer TH, Griffith JF, Lam E, Lam PK, Metreweli C. PMID: 15211127.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    255. Convergence of interferon-gamma and progesterone signaling pathways in human endometrium: role of PIASy (protein inhibitor of activated signal transducer and activator of transcription-y). Mol Endocrinol. 2004 Aug; 18(8):1988-99. Zoumpoulidou G, Jones MC, Fernandez de Mattos S, Francis JM, Fusi L, Lee YS, Christian M, Varshochi R, Lam EW, Brosens JJ. PMID: 15155784.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    256. Value of SERMs in postmenopausal women. Lancet. 2004 May 01; 363(9419):1477-8. Palmieri C, Lam EW, Vigushin D, Coombes RC. PMID: 15121421.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    257. Androgens target prohibitin to regulate proliferation of prostate cancer cells. Oncogene. 2004 Apr 15; 23(17):2996-3004. Gamble SC, Odontiadis M, Waxman J, Westbrook JA, Dunn MJ, Wait R, Lam EW, Bevan CL. PMID: 14968116.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    258. Controlled cell death, plant survival and development. Nat Rev Mol Cell Biol. 2004 Apr; 5(4):305-15. Lam E. PMID: 15071555.
      View in: PubMed   Mentions: 134     Fields:    Translation:AnimalsCells
    259. The expression of ER beta cx in human breast cancer and the relationship to endocrine therapy and survival. Clin Cancer Res. 2004 Apr 01; 10(7):2421-8. Palmieri C, Lam EW, Mansi J, MacDonald C, Shousha S, Madden P, Omoto Y, Sunters A, Warner M, Gustafsson JA, Coombes RC. PMID: 15073120.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    260. Steroid receptor action. Best Pract Res Clin Obstet Gynaecol. 2004 Apr; 18(2):265-83. Brosens JJ, Tullet J, Varshochi R, Lam EW. PMID: 15157642.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    261. Recent advance in the study of caspase-like proteases and Bax inhibitor-1 in plants: their possible roles as regulator of programmed cell death. Mol Plant Pathol. 2004 Jan 01; 5(1):65-70. Watanabe N, Lam E. PMID: 20565583.
      View in: PubMed   Mentions: 18     Fields:    
    262. Hypertriglyceridemia in lecithin-cholesterol acyltransferase-deficient mice is associated with hepatic overproduction of triglycerides, increased lipogenesis, and improved glucose tolerance. J Biol Chem. 2004 Feb 27; 279(9):7636-42. Ng DS, Xie C, Maguire GF, Zhu X, Ugwu F, Lam E, Connelly PW. PMID: 14668345.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    263. Cyclin D2 controls B cell progenitor numbers. J Leukoc Biol. 2003 Dec; 74(6):1139-43. Mohamedali A, Soeiro I, Lea NC, Glassford J, Banerji L, Mufti GJ, Lam EW, Thomas NS. PMID: 14612431.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    264. Expression of estrogen receptor beta isoforms in normal breast epithelial cells and breast cancer: regulation by methylation. Oncogene. 2003 Oct 23; 22(48):7600-6. Zhao C, Lam EW, Sunters A, Enmark E, De Bella MT, Coombes RC, Gustafsson JA, Dahlman-Wright K. PMID: 14576822.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    265. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem. 2003 Dec 12; 278(50):49795-805. Sunters A, Fernández de Mattos S, Stahl M, Brosens JJ, Zoumpoulidou G, Saunders CA, Coffer PJ, Medema RH, Coombes RC, Lam EW. PMID: 14527951.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansCells
    266. Expression of the baculovirus p35 protein in tobacco affects cell death progression and compromises N gene-mediated disease resistance response to Tobacco mosaic virus. Mol Plant Microbe Interact. 2003 Jun; 16(6):485-94. del Pozo O, Lam E. PMID: 12795375.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    267. Transcription factor IIB (TFIIB)-related protein (pBrp), a plant-specific member of the TFIIB-related protein family. Mol Cell Biol. 2003 May; 23(9):3274-86. Lagrange T, Hakimi MA, Pontier D, Courtois F, Alcaraz JP, Grunwald D, Lam E, Lerbs-Mache S. PMID: 12697827.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    268. BCR targets cyclin D2 via Btk and the p85alpha subunit of PI3-K to induce cell cycle progression in primary mouse B cells. Oncogene. 2003 Apr 17; 22(15):2248-59. Glassford J, Soeiro I, Skarell SM, Banerji L, Holman M, Klaus GG, Kadowaki T, Koyasu S, Lam EW. PMID: 12700661.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    269. Chromatin of endoreduplicated pavement cells has greater range of movement than that of diploid guard cells in Arabidopsis thaliana. J Cell Sci. 2003 Jun 01; 116(Pt 11):2195-201. Kato N, Lam E. PMID: 12692151.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    270. Commitment point during G0-->G1 that controls entry into the cell cycle. Mol Cell Biol. 2003 Apr; 23(7):2351-61. Lea NC, Orr SJ, Stoeber K, Williams GH, Lam EW, Ibrahim MA, Mufti GJ, Thomas NS. PMID: 12640120.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    271. Fibroblast growth factor 7, secreted by breast fibroblasts, is an interleukin-1beta-induced paracrine growth factor for human breast cells. J Endocrinol. 2003 Apr; 177(1):65-81. Palmieri C, Roberts-Clark D, Assadi-Sabet A, Coope RC, O'Hare M, Sunters A, Hanby A, Slade MJ, Gomm JJ, Lam EW, Coombes RC. PMID: 12697038.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    272. Differential regulation of TGA transcription factors by post-transcriptional control. Plant J. 2002 Dec; 32(5):641-53. Pontier D, Privat I, Trifa Y, Zhou JM, Klessig DF, Lam E. PMID: 12472682.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    273. An E2F-binding site mediates the activation of the proliferative isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by phosphatidylinositol 3-kinase. Biochem J. 2002 Nov 15; 368(Pt 1):283-91. Fernández de Mattos S, Lam EW, Tauler A. PMID: 12139485.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    274. Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D. Mol Cell Biol. 2002 Nov; 22(22):7842-52. Schmidt M, Fernandez de Mattos S, van der Horst A, Klompmaker R, Kops GJ, Lam EW, Burgering BM, Medema RH. PMID: 12391153.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansAnimalsCells
    275. Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1. J Biol Chem. 2002 Sep 06; 277(36):32413-6. Chopra S, Fernandez De Mattos S, Lam EW, Mann DJ. PMID: 12119282.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    276. Mechanism of cell death and disease resistance induction by transgenic expression of bacterio-opsin. Plant J. 2002 Jun; 30(5):499-509. Pontier D, Mittler R, Lam E. PMID: 12047625.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    277. H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression. J Biol Chem. 2002 Apr 19; 277(16):13761-70. Barnouin K, Dubuisson ML, Child ES, Fernandez de Mattos S, Glassford J, Medema RH, Mann DJ, Lam EW. PMID: 11827966.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    278. Direct relation between BCR-ABL tyrosine kinase activity and cyclin D2 expression in lymphoblasts. Cancer Res. 2001 Nov 01; 61(21):8005-13. Deininger MW, Vieira SA, Parada Y, Banerji L, Lam EW, Peters G, Mahon FX, Köhler T, Goldman JM, Melo JV. PMID: 11691826.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    279. BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells. Oncogene. 2001 Nov 01; 20(50):7352-67. Banerji L, Glassford J, Lea NC, Thomas NS, Klaus GG, Lam EW. PMID: 11704865.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    280. Detection of chromosomes tagged with green fluorescent protein in live Arabidopsis thaliana plants. Genome Biol. 2001; 2(11):RESEARCH0045. Kato N, Lam E. PMID: 11737944.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    281. Vav is required for cyclin D2 induction and proliferation of mouse B lymphocytes activated via the antigen Receptor. J Biol Chem. 2001 Nov 02; 276(44):41040-8. Glassford J, Holman M, Banerji L, Clayton E, Klaus GG, Turner M, Lam EW. PMID: 11546804.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    282. Trans-dominant suppression of plant TGA factors reveals their negative and positive roles in plant defense responses. Plant J. 2001 Sep; 27(6):529-38. Pontier D, Miao ZH, Lam E. PMID: 11576436.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    283. The influence of INK4 proteins on growth and self-renewal kinetics of hematopoietic progenitor cells. Blood. 2001 May 01; 97(9):2604-10. Lewis JL, Chinswangwatanakul W, Zheng B, Marley SB, Nguyen DX, Cross NC, Banerji L, Glassford J, Thomas NS, Goldman JM, Lam EW, Gordon MY. PMID: 11313248.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    284. BCR-ABL-expressing cells transduced with the HSV-tk gene die by apoptosis upon treatment with ganciclovir. Mol Ther. 2001 May; 3(5 Pt 1):642-52. Rivas C, Miller AR, Collado M, Lam EW, Apperley JF, Melo JV. PMID: 11356068.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    285. BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27Kip1 expression. J Biol Chem. 2001 Jun 29; 276(26):23572-80. Parada Y, Banerji L, Glassford J, Lea NC, Collado M, Rivas C, Lewis JL, Gordon MY, Thomas NS, Lam EW. PMID: 11323429.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    286. Applications, and efficient large-scale production, of recombinant human epidermal growth factor. Biotechnol Genet Eng Rev. 2001; 18:51-71. Wong WR, Lam E, Huang RC, Wong RS, Morris C, Hackett J. PMID: 11530698.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    287. Ligation of the WC1 receptor induces gamma delta T cell growth arrest through fumonisin B1-sensitive increases in cellular ceramide. J Immunol. 2000 Oct 01; 165(7):3564-70. Kirkham PA, Takamatsu HH, Lam EW, Parkhouse RM. PMID: 11034356.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    288. Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1. J Biol Chem. 2000 Jul 21; 275(29):21960-8. Collado M, Medema RH, Garcia-Cao I, Dubuisson ML, Barradas M, Glassford J, Rivas C, Burgering BM, Serrano M, Lam EW. PMID: 10791951.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    289. Immunolocalization and adenoviral vector-mediated manganese superoxide dismutase gene transfer to experimental oral tumors. J Dent Res. 2000 Jun; 79(6):1410-7. Lam EW, Hammad HM, Zwacka R, Darby CJ, Baumgardner KR, Davidson BL, Oberley TD, Engelhardt JF, Oberley LW. PMID: 10890721.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    290. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development. Int Immunol. 2000 May; 12(5):631-8. Solvason N, Wu WW, Parry D, Mahony D, Lam EW, Glassford J, Klaus GG, Sicinski P, Weinberg R, Liu YJ, Howard M, Lees E. PMID: 10784609.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    291. Cyclin D3 compensates for loss of cyclin D2 in mouse B-lymphocytes activated via the antigen receptor and CD40. J Biol Chem. 2000 Feb 04; 275(5):3479-84. Lam EW, Glassford J, Banerji L, Thomas NS, Sicinski P, Klaus GG. PMID: 10652342.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    292. NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid. Mol Plant Microbe Interact. 2000 Feb; 13(2):191-202. Zhou JM, Trifa Y, Silva H, Pontier D, Lam E, Shah J, Klessig DF. PMID: 10659709.
      View in: PubMed   Mentions: 107     Fields:    Translation:AnimalsCells
    293. Enzyme biosensor for studying therapeutics of Alzheimer's disease. Biosens Bioelectron. 2000; 15(9-10):541-7. Lenigk R, Lam E, Lai A, Wang H, Han Y, Carlier P, Renneberg R. PMID: 11419651.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    294. Different functions are required for initiation and maintenance of immortalization of rat embryo fibroblasts by SV40 large T antigen. Oncogene. 1999 Dec 02; 18(51):7343-50. Powell AJ, Darmon AJ, Gonos ES, Lam EW, Peden KW, Jat PS. PMID: 10602490.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    295. Modulation of E2F activity in primary mouse B cells following stimulation via surface IgM and CD40 receptors. Eur J Immunol. 1999 10; 29(10):3380-9. Lam EW, Glassford J, van der Sman J, Banerji L, Pizzey AR, Shaun N, Thomas B, Klaus GG. PMID: 10540350.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    296. Modulation of E2F complexes during G0 to S phase transition in human primary B-lymphocytes. J Biol Chem. 1999 Apr 23; 274(17):12009-16. van der Sman J, Thomas NS, Lam EW. PMID: 10207023.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    297. Nonspecific inhibition of myogenic tone by PD98059, a MEK1 inhibitor, in rat middle cerebral arteries. Biochem Biophys Res Commun. 1999 Apr 13; 257(2):523-7. Lagaud GJ, Lam E, Lui A, van Breemen C, Laher I. PMID: 10198244.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    298. Markers for hypersensitive response and senescence show distinct patterns of expression. Plant Mol Biol. 1999 Apr; 39(6):1243-55. Pontier D, Gan S, Amasino RM, Roby D, Lam E. PMID: 10380810.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    299. Signals controlling the expression of cytosolic ascorbate peroxidase during pathogen-induced programmed cell death in tobacco. Plant Mol Biol. 1999 Mar; 39(5):1025-35. Mittler R, Lam E, Shulaev V, Cohen M. PMID: 10344207.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    300. Rapid dephosphorylation of p107 following UV irradiation. Oncogene. 1999 Jan 21; 18(3):679-88. Voorhoeve PM, Watson RJ, Farlie PG, Bernards R, Lam EW. PMID: 9989818.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    301. Inhibition of myogenic tone by mibefradil in rat cerebral arteries. Eur J Pharmacol. 1998 Oct 02; 358(2):165-8. Lam E, Skarsgard P, Laher I. PMID: 9808266.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    302. Transcription factor E2F controls the reversible gamma delta T cell growth arrest mediated through WC1. J Immunol. 1998 Aug 15; 161(4):1630-6. Kirkham PA, Lam EW, Takamatsu HH, Parkhouse RM. PMID: 9712024.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    303. The p53 tumor suppressor inhibits transcription of the TATA-less mouse DP1 promoter. J Biol Chem. 1998 May 01; 273(18):10972-8. Gopalkrishnan RV, Lam EW, Kedinger C. PMID: 9556576.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    304. Modulation of E2F activity via signaling through surface IgM and CD40 receptors in WEHI-231 B lymphoma cells. J Biol Chem. 1998 Apr 17; 273(16):10051-7. Lam EW, Choi MS, van der Sman J, Burbidge SA, Klaus GG. PMID: 9545352.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    305. Adenovirus-mediated manganese superoxide dismutase gene transfer to hamster cheek pouch carcinoma cells. Cancer Res. 1997 Dec 15; 57(24):5550-6. Lam EW, Zwacka R, Engelhardt JF, Davidson BL, Domann FE, Yan T, Oberley LW. PMID: 9407966.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    306. DNA-binding properties, genomic organization and expression pattern of TGA6, a new member of the TGA family of bZIP transcription factors in Arabidopsis thaliana. Plant Mol Biol. 1997 Jun; 34(3):403-15. Xiang C, Miao Z, Lam E. PMID: 9225852.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    307. Pathogen-induced programmed cell death in tobacco. J Cell Sci. 1997 Jun; 110 ( Pt 11):1333-44. Mittler R, Simon L, Lam E. PMID: 9202394.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    308. CD40: a pivotal receptor in the determination of life/death decisions in B lymphocytes. Int Rev Immunol. 1997; 15(1-2):5-31. Klaus GG, Choi MS, Lam EW, Johnson-Léger C, Cliff J. PMID: 9178070.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    309. Coordinated activation of as-1-type elements and a tobacco glutathione S-transferase gene by auxins, salicylic acid, methyl-jasmonate and hydrogen peroxide. Plant Mol Biol. 1996 Nov; 32(3):415-26. Xiang C, Miao ZH, Lam E. PMID: 8980490.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    310. The conserved ELK-homeodomain of KNOTTED-1 contains two regions that signal nuclear localization. Plant Mol Biol. 1996 Jan; 30(1):1-14. Meisel L, Lam E. PMID: 8616227.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    311. Induction of bimodal programmed cell death in malignant cells by the derivative Ukrain (NSC-631570). Drugs Exp Clin Res. 1996; 22(3-5):73-9. Liepins A, Nowicky JW, Bustamante JO, Lam E. PMID: 8899308.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    312. Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1. EMBO J. 1995 Dec 15; 14(24):6184-92. O'Connor DJ, Lam EW, Griffin S, Zhong S, Leighton LC, Burbidge SA, Lu X. PMID: 8557038.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    313. A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor. J Biol Chem. 1995 Nov 03; 270(44):26511-22. Lam E, Martin MM, Timerman AP, Sabers C, Fleischer S, Lukas T, Abraham RT, O'Keefe SJ, O'Neill EA, Wiederrecht GJ. PMID: 7592869.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    314. Binding site requirements and differential representation of TGF factors in nuclear ASF-1 activity. Nucleic Acids Res. 1995 Sep 25; 23(18):3778-85. Lam E, Lam YK. PMID: 7479010.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    315. Functional conservation of the cell cycle-regulating transcription factor DRTF1/E2F and its pathway of control in Drosophila melanogaster. J Cell Sci. 1995 Sep; 108 ( Pt 9):2945-54. Hao XF, Alphey L, Bandara LR, Lam EW, Glover D, La Thangue NB. PMID: 8537434.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    316. Cell-cycle regulation of human B-myb transcription. Gene. 1995 Jul 28; 160(2):277-81. Lam EW, Bennett JD, Watson RJ. PMID: 7642110.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    317. Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs. Gene. 1995 Jul 28; 160(2):297-302. Lam E, Martin M, Wiederrecht G. PMID: 7543869.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    318. Construction of a trans-dominant inhibitor for members of the TGA family of transcription factors conserved in higher plants. Plant J. 1995 Jun; 7(6):887-96. Miao ZH, Lam E. PMID: 7599649.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    319. Proto-oncogenic properties of the DP family of proteins. Oncogene. 1995 Apr 20; 10(8):1529-36. Jooss K, Lam EW, Bybee A, Girling R, Müller R, La Thangue NB. PMID: 7731707.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    320. Targeted disruption of the TGA3 locus in Arabidopsis thaliana. Plant J. 1995 Feb; 7(2):359-65. Miao ZH, Lam E. PMID: 7704051.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    321. Domain analysis of the plant DNA-binding protein GT1a: requirement of four putative alpha-helices for DNA binding and identification of a novel oligomerization region. Mol Cell Biol. 1995 Feb; 15(2):1014-20. Lam E. PMID: 7823917.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    322. Study of HIV antibody screening for blood donors by a pooling-serum method. Vox Sang. 1995; 69(3):255-6. Ji Y, Qu D, Jia G, Ren Q, Fang CT, Lam E, Ha BT, Dodd RY, Sullivan MT, Williams AE. PMID: 8578741.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    323. Abundance of nuclear DNA topoisomerase II is correlated with proliferation in Arabidopsis thaliana. Nucleic Acids Res. 1994 Dec 25; 22(25):5729-36. Xie S, Lam E. PMID: 7838729.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    324. DP and E2F proteins: coordinating transcription with cell cycle progression. Curr Opin Cell Biol. 1994 Dec; 6(6):859-66. Lam EW, La Thangue NB. PMID: 7880534.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    325. Molecular characterization of Xenopus laevis DP proteins. Mol Biol Cell. 1994 Oct; 5(10):1081-92. Girling R, Bandara LR, Ormondroyd E, Lam EW, Kotecha S, Mohun T, La Thangue NB. PMID: 7865876.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    326. DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein. EMBO J. 1994 Jul 01; 13(13):3104-14. Bandara LR, Lam EW, Sørensen TS, Zamanian M, Girling R, La Thangue NB. PMID: 8039504.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    327. TGA3 is a distinct member of the TGA family of bZIP transcription factors in Arabidopsis thaliana. Plant Mol Biol. 1994 Apr; 25(1):1-11. Miao ZH, Liu X, Lam E. PMID: 8003690.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    328. HPV16 E7 oncoprotein deregulates B-myb expression: correlation with targeting of p107/E2F complexes. EMBO J. 1994 Feb 15; 13(4):871-8. Lam EW, Morris JD, Davies R, Crook T, Watson RJ, Vousden KH. PMID: 8112300.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    329. Two binding sites for the plant transcription factor ASF-1 can respond to auxin treatments in transgenic tobacco. J Biol Chem. 1994 Jan 07; 269(1):668-75. Liu X, Lam E. PMID: 8276868.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    330. Analysis of tissue-specific elements in the CaMV 35S promoter. Results Probl Cell Differ. 1994; 20:181-96. Lam E. PMID: 8036315.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    331. An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J. 1993 Jul; 12(7):2705-13. Lam EW, Watson RJ. PMID: 8334989.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    332. Transcription regulation by murine B-myb is distinct from that by c-myb. Nucleic Acids Res. 1993 Jan 25; 21(2):267-72. Watson RJ, Robinson C, Lam EW. PMID: 8382794.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    333. Characterization and cell cycle-regulated expression of mouse B-myb. Oncogene. 1992 Sep; 7(9):1885-90. Lam EW, Robinson C, Watson RJ. PMID: 1501895.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    334. A tobacco DNA binding protein that interacts with a light-responsive box II element. Plant Cell. 1992 Jul; 4(7):831-8. Perisic O, Lam E. PMID: 1392597.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    335. Regional 31P magnetic resonance spectroscopy of exercising human masseter muscle. Arch Oral Biol. 1992 Jan; 37(1):49-56. Lam EW, Hannam AG. PMID: 1596208.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    336. Tetramer of a 21-base pair synthetic element confers seed expression and transcriptional enhancement in response to water stress and abscisic acid. J Biol Chem. 1991 Sep 15; 266(26):17131-5. Lam E, Chua NH. PMID: 1832669.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    337. Estimation of tendon-plane orientation within human masseter muscle from reconstructed magnetic resonance images. Arch Oral Biol. 1991; 36(11):845-53. Lam EW, Hannam AG, Christiansen EL. PMID: 1763981.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    338. A metal-dependent DNA-binding protein interacts with a constitutive element of a light-responsive promoter. Plant Cell. 1990 Sep; 2(9):857-66. Lam E, Kano-Murakami Y, Gilmartin P, Niner B, Chua NH. PMID: 2152132.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    339. Plant nuclear factor ASF-1 binds to an essential region of the nopaline synthase promoter. J Biol Chem. 1990 Jun 15; 265(17):9909-13. Lam E, Katagiri F, Chua NH. PMID: 2351681.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    340. GT-1 binding site confers light responsive expression in transgenic tobacco. Science. 1990 Apr 27; 248(4954):471-4. Lam E, Chua NH. PMID: 2330508.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    341. From footprint to function: an approach to study gene expression and regulatory factors in transgenic plants. Genet Eng (N Y). 1990; 12:73-86. Lam E. PMID: 1366708.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    342. ASF-2: a factor that binds to the cauliflower mosaic virus 35S promoter and a conserved GATA motif in Cab promoters. Plant Cell. 1989 Dec; 1(12):1147-56. Lam E, Chua NH. PMID: 2535536.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    343. Characterization of phytochrome-regulated gene expression in a photoautotrophic cell suspension: possible role for calmodulin. Mol Cell Biol. 1989 Nov; 9(11):4819-23. Lam E, Benedyk M, Chua NH. PMID: 2689868.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    344. Phytochrome activation of two nuclear genes requires cytoplasmic protein synthesis. EMBO J. 1989 Oct; 8(10):2777-83. Lam E, Green PJ, Wong M, Chua NH. PMID: 2583082.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    345. Two tobacco DNA-binding proteins with homology to the nuclear factor CREB. Nature. 1989 Aug 31; 340(6236):727-30. Katagiri F, Lam E, Chua NH. PMID: 2528073.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    346. Imaging orofacial tissues by magnetic resonance. Oral Surg Oral Med Oral Pathol. 1989 Jul; 68(1):2-8. Lam EW, Hannam AG, Wood WW, Fache JS, Watanabe M. PMID: 2755685.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    347. Streptozotocin-induced deficits in sex behavior and neuroendocrine function in male rats. Endocrinology. 1989 Apr; 124(4):1737-43. Steger RW, Amador A, Lam E, Rathert J, Weis J, Smith MS. PMID: 2522388.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    348. Risk factors and 10-year breast cancer survival in northern Alberta. Breast Cancer Res Treat. 1989 Mar; 13(2):143-51. Lees AW, Jenkins HJ, May CL, Cherian G, Lam EW, Hanson J. PMID: 2730961.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    349. Nearest-neighbor relationships of the constituent polypeptides in plastoquinol-plastocyanin oxidoreductase. Biochim Biophys Acta. 1986 Mar 12; 848(3):324-32. Lam E. PMID: 3081025.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    350. Characterization of a photosynthetic mutant of Lemna lacking the cytochrome b6-f complex. Biochim Biophys Acta. 1985 Oct 29; 810(1):106-9. Lam E, Malkin R. PMID: 3899174.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    351. Characterization of alpha-adrenoceptor populations. Quantitative relationships between cardiovascular effects initiated at central and peripheral alpha-adrenoceptors. J Med Chem. 1981 May; 24(5):502-7. Timmermans PB, de Jonge A, van Meel JC, Slothorst-Grisdijk FP, Lam E, van Zwieten PA. PMID: 6264080.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
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