Jane Symington, MD, PhD

Title(s)Assistant Professor, Pediatrics
SchoolSchool of Medicine
Address550 16th Street, #4833
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    Yale University, New Haven, CTBS2007Biology
    Washington University in St. Louis, St. Louis, MOMD, PhD2016Molecular Microbiology and Microbial Pathogenesis
    University of California San Francisco, San Francisco, CA2019Pediatric Residency
    University of California San Francisco, San Francisco, CA2022Pediatric Infectious Diseases Fellowship

    Collapse Overview 
    Collapse Overview
    Dr. Jane Symington is a pediatric physician scientist investigating the pathogenesis of Coccidioides, the fungus that causes Coccidioidomycosis, more commonly known as Valley Fever. Her current work focuses on dissecting the interactions between Coccidioides and innate immune cells to identify and target pathways important for fungal virulence or protective host responses.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages. PLoS Pathog. 2022 09; 18(9):e1010237. Cohen A, Jeng EE, Voorhies M, Symington J, Ali N, Rodriguez RA, Bassik MC, Sil A. PMID: 36174103; PMCID: PMC9578593.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence. Autophagy. 2019 03; 15(3):527-542. Wang C, Bauckman KA, Ross ASB, Symington JW, Ligon MM, Scholtes G, Kumar A, Chang HW, Twentyman J, Fashemi BE, Xavier RJ, Mysorekar IU. PMID: 30335568; PMCID: PMC6351132.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    3. ATG16L1 deficiency in macrophages drives clearance of uropathogenic E. coli in an IL-1β-dependent manner. Mucosal Immunol. 2015 Nov; 8(6):1388-99. Symington JW, Wang C, Twentyman J, Owusu-Boaitey N, Schwendener R, Núñez G, Schilling JD, Mysorekar IU. PMID: 25669147; PMCID: PMC4532666.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    4. Estrogenic modulation of uropathogenic Escherichia coli infection pathogenesis in a murine menopause model. Infect Immun. 2013 Mar; 81(3):733-9. Wang C, Symington JW, Ma E, Cao B, Mysorekar IU. PMID: 23264047; PMCID: PMC3584860.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    5. ATG16L1 and pathogenesis of urinary tract infections. Autophagy. 2012 Nov; 8(11):1693-4. Wang C, Symington JW, Mysorekar IU. PMID: 22874553; PMCID: PMC3494604.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    6. Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo. Proc Natl Acad Sci U S A. 2012 Jul 03; 109(27):11008-13. Wang C, Mendonsa GR, Symington JW, Zhang Q, Cadwell K, Virgin HW, Mysorekar IU. PMID: 22715292; PMCID: PMC3390880.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
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