Jason Smith, MD

Title(s)Professor, Surgery
SchoolSchool of Medicine
Address513 Parnassus Avenue, MSB, #309F
San Francisco CA 94143
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    Collapse Biography 
    Collapse Education and Training
    Baylor University , Waco, TxBA12/1993University Scholar
    Loyola University Medical School, Chicago, ILMD06/2002Medicine
    Loyola University Medical Center, Chicago, IL06/2009General Surgery
    Loyola University Medical Center, Burn Shock Trauma Center, Chicago, IL06/2005Research Fellowship
    Loyola University Medical Center, Chicago, IL06/2011Cardiothoracic Surgery
    Stanford University Hospital and Clinics, Palo Alto, CA06/2012Heart and Lung Transplant and Mechanical Circulatory Support

    Collapse Overview 
    Collapse Overview
    Dr. Jason W. Smith is a cardiac and transplant surgeon who specializes in heart transplantation and the use of mechanical circulatory support, such as artificial heart pumps and left ventricular assist devices. He has expertise in complex cardiac procedures that include mitral valve repair and replacement, aortic valve surgery, transcatheter aortic valve procedures (minimally invasive techniques to replace a failing valve), surgeries to treat the ascending aorta and aortic arch, treatment of endocarditis (infections of the heart's inner lining), operations to correct atrial fibrillation (irregular and often rapid heartbeats), and sternal repair and reconstruction. He also manages extracorporeal membrane oxygenation (ECMO), which supports the heart and lungs by using a machine to oxygenate blood outside of the body. He is the surgical director of UCSF's heart transplantation and mechanical circulatory support programs.

    Smith has been active in a national effort to increase access to heart transplantation by improving the use of donor organs. He served as a primary investigator for a nationwide clinical trial on donation after cardiac death.

    Smith earned his medical degree from the Stritch School of Medicine at Loyola University Chicago, then completed a residency in general surgery and a fellowship in cardiothoracic surgery at Loyola University Medical Center. He completed a fellowship in heart and lung transplantation at Stanford Medicine. Upon completing his training, he joined the surgical faculty at the University of Washington. Prior to joining UCSF, he served as surgical director of transplant and mechanical circulatory support at the University of Wisconsin – Madison.

    Smith serves on the membership and professional standards committee of the national Organ Procurement and Transplantation Network. He frequently makes presentations on issues related to organ transplantation and utilization and belongs to numerous professional and honorary societies. He is a San Francisco native.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Distance to Burn Center Does Not Impact Long-term Anxiety and Depression Risk Following Burn Injury. J Burn Care Res. 2024 Apr 13. Risinger WB, Dye CN, Thompson SK, Uma CV, Keeven DD, Nash NA, Smith JW, Bozeman MC. PMID: 38609181.
      View in: PubMed   Mentions:
    2. Author Reply: "What do we mean by source control and what are we trying to accomplish with an open abdomen in severe complicated intra-abdominal sepsis?" J Trauma Acute Care Surg. 2024 Feb 14. Risinger WB, Smith JW. PMID: 38351497.
      View in: PubMed   Mentions:    Fields:    
    3. Applying the antecedent, behaviour, and consequence taxonomy to unintentional firearm injury as determined by a collaborative firearm injury database. Inj Prev. 2024 Jan 25; 30(1):39-45. Risinger WB, Nickols AK, Harris AN, Benns MV, Nash NA, Bozeman MC, Pera SJ, Coleman JC, Franklin GA, Smith JW, Harbrecht BG, Miller KR. PMID: 37857476.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Increasing Utilization of Extended Criteria Donor Hearts for Transplantation: The OCS Heart EXPAND Trial. JACC Heart Fail. 2024 Mar; 12(3):438-447. Schroder JN, Patel CB, DeVore AD, Casalinova S, Koomalsingh KJ, Shah AS, Anyanwu AC, D'Alessandro DA, Mudy K, Sun B, Strueber M, Khaghani A, Shudo Y, Esmailian F, Liao K, Pagani FD, Silvestry S, Wang IW, Salerno CT, Absi TS, Madsen JC, Mancini D, Fiedler AG, Milano CA, Smith JW. PMID: 38276933.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    5. A Decade of Analysis of Unplanned Extubation Etiology in Trauma Patients Including the Impact of the COVID Pandemic. Respir Care. 2023 Sep 26. Harbrecht BG, Miller KR, Egger ME, Nash NA, Doan R, Georgel J, Franklin GA, Smith JW, Bozeman MC, Benns MV. PMID: 37751930; PMCID: PMC10753617.
      View in: PubMed   Mentions: 1     Fields:    
    6. Expanding the Donation After Circulatory Death Transplant Pool in the United States. Ann Thorac Surg. 2023 12; 116(6):1121-1123. Fiedler A, Miller PN, Smith JW. PMID: 37660964.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Plasma resuscitation improves and restores intestinal microcirculatory physiology following haemorrhagic shock. Vox Sang. 2023 Oct; 118(10):863-872. Schucht JE, Harbrecht BG, Bond LM, Risinger WB, Matheson PJ, Smith JW. PMID: 37563931.
      View in: PubMed   Mentions: 1     Fields:    
    8. Damage control surgery in emergency general surgery: What you need to know. J Trauma Acute Care Surg. 2023 11 01; 95(5):770-779. Risinger WB, Smith JW. PMID: 37439768.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study. Trauma Surg Acute Care Open. 2023; 8(1):e001017. Ziesmann M, Byerly S, Yeh DD, Boltz M, Gelbard R, Haut ER, Smith JW, Stein DM, Zarzaur BL, Bensard DD, Biffl WL, Boyd A, Brommeland T, Cothren Burlew C, Fabian T, Lauerman M, Leichtle S, Moore EE, Timmons S, Vogt K, Nahmias J. PMID: 37342820; PMCID: PMC10277546.
      View in: PubMed   Mentions: 1  
    10. Transplantation Outcomes with Donor Hearts after Circulatory Death. N Engl J Med. 2023 Jun 08; 388(23):2121-2131. Schroder JN, Patel CB, DeVore AD, Bryner BS, Casalinova S, Shah A, Smith JW, Fiedler AG, Daneshmand M, Silvestry S, Geirsson A, Pretorius V, Joyce DL, Um JY, Esmailian F, Takeda K, Mudy K, Shudo Y, Salerno CT, Pham SM, Goldstein DJ, Philpott J, Dunning J, Lozonschi L, Couper GS, Mallidi HR, Givertz MM, Pham DT, Shaffer AW, Kai M, Quader MA, Absi T, Attia TS, Shukrallah B, Sun BC, Farr M, Mehra MR, Madsen JC, Milano CA, D'Alessandro DA. PMID: 37285526.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    11. Comment on: Detection and management of HLA sensitization in candidates for adult heart transplantation. J Heart Lung Transplant. 2023 Apr 21. Fiedler AG, Klein L, DeMarco T, Kouretas P, Smith JW. PMID: 37088342.
      View in: PubMed   Mentions:    Fields:    
    12. Establishing a core outcomes set for massive transfusion: An Eastern Association for the Surgery of Trauma modified Delphi method consensus study. J Trauma Acute Care Surg. 2023 06 01; 94(6):784-790. Gelbard RB, Nahmias J, Byerly S, Ziesmann M, Stein D, Haut ER, Smith JW, Boltz M, Zarzaur B, Callum J, Cotton BA, Cripps M, Gunter OL, Holcomb JB, Kerby J, Kornblith LZ, Moore EE, Riojas CM, Schreiber M, Sperry JL, Yeh DD. PMID: 36727810.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Molecules, Machines, and the Perfusate Milieu: Organ Preservation and Emerging Concepts for Heart Transplant. Innovations (Phila). 2022 09; 17(5):363-367. Wisneski A, Smith JW, Nguyen TC, Fiedler AG. PMID: 36271669.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Effect of Plasma Resuscitation with Adjunctive Peritoneal Resuscitation on Hepatic Blood Flow and End-Organ Damage after Hemorrhagic Shock. J Am Coll Surg. 2022 10 01; 235(4):643-653. Smith JW, Schucht JE, Harbrecht BG, Bond LM, Matheson PJ. PMID: 36106867.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. Direct Peritoneal Resuscitation for Trauma. Adv Surg. 2022 Sep; 56(1):229-245. Pera SJ, Schucht J, Smith JW. PMID: 36096569.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    16. A new pandemic and an old epidemic: The impact of COVID-19 and gun violence as measured by years of potential life lost in a US city. Surgery. 2022 11; 172(5):1555-1562. Risinger WB, Pera SJ, Bhutiani N, Ruther M, Harbrecht BG, Smith JW, Benns MV, Miller KR. PMID: 36055817; PMCID: PMC9283608.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    17. Normothermic regional perfusion surgical technique for the procurement of cardiac donors after circulatory death. JTCVS Tech. 2022 Apr; 12:113-115. Fiedler AG, DeVries S, Czekajlo C, Smith JW. PMID: 35403051; PMCID: PMC8987395.
      View in: PubMed   Mentions:
    18. Unconventional use of total artificial heart in a patient with severe, destructive prosthetic valve endocarditis. J Card Surg. 2022 Feb; 37(2):443-444. Johnstad C, Bomareddi S, Hermsen JL, Smith JW, Fiedler AG. PMID: 34766385.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Survival after orthotopic heart transplantation in patients with BMI > = 35 with and without diabetes. Clin Transplant. 2021 10; 35(10):e14400. Fiedler AG, Stalter L, Marka N, Dhingra R, Hermsen JL, Smith JW. PMID: 34181771.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Left ventricular assist device implantation by bi-thoracotomy technique: A single-center perspective. J Card Surg. 2021 Jul; 36(7):2342-2347. Stoeckl EM, Smith JW, Dhingra R, Fiedler AG. PMID: 33861471.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Risk factors and outcomes for delayed kidney graft function in simultaneous heart and kidney transplant recipients: A UNOS/OPTN database analysis. Am J Transplant. 2021 09; 21(9):3005-3013. Parajuli S, Karim AS, Muth BL, Leverson GE, Yang Q, Dhingra R, Smith JW, Foley DP, Mandelbrot DA. PMID: 33565674.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Successful heart transplantation in a patient who recovered from COVID-19. J Card Surg. 2021 Mar; 36(3):1148-1149. Johnstad CM, Murray D, Dhingra R, Smith JW, Fiedler AG. PMID: 33448478; PMCID: PMC8014622.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    23. Orthotopic Heart Transplant: How I Teach It. Ann Thorac Surg. 2021 02; 111(2):398-400. Fiedler AG, Hermsen JL, Bommareddi S, Smith JW. PMID: 33506767.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Amiodarone Use Prior to Cardiac Transplant Impacts Early Post-Transplant Survival. Cardiovasc Drugs Ther. 2021 02; 35(1):33-40. Allana SS, Rajput FA, Smith JW, Lozonschi L, Liou JI, Johnson M, Kohmoto T, Dhingra R. PMID: 33074524.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee. J Card Fail. 2020 Mar; 26(3):254-269. Writing Committee Members, Yancy CW, Drazner MH, Coffin ST, Cornwell W, Desai S, Erwin JP, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin C, Meehan K, Morrow DA, Schlendorf K, Smith JW, Stevens GR, ACC Competency Management Committee, Arrighi JA, Mendes LA, Adams JE, Brush JE, Dec GW, Denktas A, Fernandes S, Freeman R, Francis SA, Hahn RT, Halperin JL, Housholder-Hughes SD, Khan SS, Klarich K, Lin CH, Marine JE, McPherson JA, Niazi K, Ryan T, Solomon MA, Spicer RL, Tam M, Wang A, Weissman G, Weitz HH, Williams ES. PMID: 32081473.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee. J Am Coll Cardiol. 2020 03 17; 75(10):1212-1230. Yancy CW, Drazner MH, Coffin ST, Cornwell W, Desai S, Erwin JP, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin CM, Meehan K, Morrow DA, Schlendorf K, Smith JW, Stevens GR. PMID: 32081442.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Long-term discontinuation of warfarin in a patient with HeartMate 3 left ventricular assist device without complication. J Card Surg. 2020 Feb; 35(2):447-449. Fiedler AG, Hermsen JL, Smith JW, Dhingra R. PMID: 31730719.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Small Left Ventricular Size Is an Independent Risk Factor for Ventricular Assist Device Thrombosis. ASAIO J. 2019 02; 65(2):152-159. Chivukula VK, Beckman JA, Prisco AR, Lin S, Dardas TF, Cheng RK, Farris SD, Smith JW, Mokadam NA, Mahr C, Aliseda A. PMID: 29677037; PMCID: PMC6193874.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    29. Left Ventricular Assist Device Inflow Cannula Angle and Thrombosis Risk. Circ Heart Fail. 2018 04; 11(4):e004325. Chivukula VK, Beckman JA, Prisco AR, Dardas T, Lin S, Smith JW, Mokadam NA, Aliseda A, Mahr C. PMID: 29666072.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    30. Dilemmas in Dual Disease: Complexity and Futility in Prosthetic Valve Endocarditis and Substance Use Disorder. Am J Bioeth. 2018 01; 18(1):76-78. Kirkpatrick JN, Smith JW. PMID: 29313791.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    31. Invited Commentary. Ann Thorac Surg. 2017 05; 103(5):1511-1512. Smith JW, Mokadam NA. PMID: 28431696.
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    32. Pulmonary function tests do not predict mortality in patients undergoing continuous-flow left ventricular assist device implantation. J Thorac Cardiovasc Surg. 2017 12; 154(6):1959-1970.e1. Bedzra EKS, Dardas TF, Cheng RK, Pal JD, Mahr C, Smith JW, Shively K, Masri SC, Levy WC, Mokadam NA. PMID: 28526500.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. The Benefit of Donor-Recipient Matching for Patients Undergoing Heart Transplantation. J Am Coll Cardiol. 2017 Apr 04; 69(13):1707-1714. Nguyen VP, Mahr C, Mokadam NA, Pal J, Smith JW, Dardas TF. PMID: 28359517.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Outflow Graft Obstruction Treated With Transcatheter Management: A Novel Therapy for a New Diagnosis. Ann Thorac Surg. 2017 Jan; 103(1):e101-e104. Bhamidipati CM, Pal JD, Jones TK, McCabe JM, Reisman M, Smith JW, Mahr C, Mokadam NA. PMID: 28007258.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Successful Repair of Acute Type A Aortic Dissection 15 Years Following Bilateral Lung Transplantation. J Card Surg. 2016 Jan; 31(1):72-3. Hermsen JL, Madathil R, Berfield KS, Li K, Smith JW, Mulligan MS. PMID: 26585692.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Endovascular Repair for Type A Aortic Dissection After Transcatheter Aortic Valve Replacement With a Medtronic CoreValve. Ann Thorac Surg. 2015 Oct; 100(4):1444-6. Berfield KK, Sweet MP, McCabe JM, Reisman M, Mackensen GB, Mokadam NA, Dean LS, Smith JW. PMID: 26434441.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    37. Systematic donor selection review process improves cardiac transplant volumes and outcomes. J Thorac Cardiovasc Surg. 2016 Jan; 151(1):238-43. Smith JW, O'Brien KD, Dardas T, Pal JD, Fishbein DP, Levy WC, Mahr C, Masri SC, Cheng RK, Stempien-Otero A, Mokadam NA. PMID: 26428474.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    38. Periportal fibrosis without cirrhosis does not affect outcomes after continuous flow ventricular assist device implantation. J Thorac Cardiovasc Surg. 2016 Jan; 151(1):230-5. Sargent JE, Dardas TF, Smith JW, Pal JD, Cheng RK, Masri SC, Shively KR, Colyer LM, Mahr C, Mokadam NA. PMID: 26421983.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Late Surgical Bleeding Following Total Artificial Heart Implantation. J Card Surg. 2015 Oct; 30(10):771-4. Hermsen JL, Smith JW, Pal JD, Mahr C, Masri SC, Dardas TF, Cheng RK, Mokadam NA. PMID: 26286927.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Self-administration education and polypharmacy in mechanical circulatory support patients. J Heart Lung Transplant. 2013 Nov; 32(11):1141-2. Hermsen JL, Smith JW, Mokadam NA. PMID: 23968810.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    41. The influence of (18)flourodeoxyglucose positron emission tomography on the management of gastroesophageal junction carcinoma. Am J Surg. 2009 Mar; 197(3):308-12. Smith JW, Moreira J, Abood G, Aranha GV, Nagda S, Wagner RH, Shoup M. PMID: 19245906.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    42. Immunologic responses to critical injury and sepsis. J Intensive Care Med. 2006 May-Jun; 21(3):160-72. Smith JW, Gamelli RL, Jones SB, Shankar R. PMID: 16672638.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    43. New perspectives for a new century: implications of pathogen responses for the future of antimicrobial therapy. J Burn Care Res. 2006 May-Jun; 27(3):251-64. Melstrom KA, Smith JW, Gamelli RL, Shankar R. PMID: 16679890.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
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