Javier Caravaca Rodriguez, PhD
Overview
With my background in nuclear and particle physics, and expertise in particle detectors, I develop cutting-edge radiation detectors to improve current diagnosis and therapy techniques for a number of diseases, including cancer. My main interests are exploring novel designs for SPECT and PET systems to improve their performance and expand their range of application to other pathologies. In particular, I develop new SPECT detectors for alpha and beta theranostics, explore new avenues of exploiting Cherenkov light in TOF-PET, and spearhead Monte Carlo techniques to improve dosimetry in preclinical radiation therapy.
Biography
| University of Granada, Spain | B.S. | 07/2009 | Physics |
| University of Barcelona, Spain | MSc | 06/2010 | Particle Physics and Cosmology |
| University Autonomous of Barcelona, Spain | PhD | 07/2014 | Experimental Particle Physics |
| University of California, Berkeley, US | Postdoctoral | 08/2020 | Neutrino Physics |
Research
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Clinical Imaging of 225Ac in a PET Scanner via Time-of-Flight Cascade γ-Ray Imaging. J Nucl Med. 2026 Sep 30.
Caravaca J, Seo Y, Cabello J, Siegel SB, Flavell RR, Hope TA. PMID: 42816123.
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Quantitative SPECT imaging of 225Ac and its daughters in mice in vivo. Med Phys. 2026 Sep; 53(9):e70674.
Du S, Bobba KN, Peter R, Gullberg GT, Flavell RR, Caravaca J, Seo Y. PMID: 42740381; PMCID: PMC13575294.
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Performance Evaluation of Single- and Double-Layer CZT Compton Cameras for 225Ac Imaging. IEEE Trans Nucl Sci. 2026 Apr; 73(4):1481-1494.
Song G, Das B, Seo Y, Cho G, Caravaca J. PMID: 42534274; PMCID: PMC13420029.
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Compton Imaging of Ac-225 In Pre-clinical Phantoms With a 3D-positioning CZT Camera. IEEE Trans Radiat Plasma Med Sci. 2026 Jan; 10(1):112-125.
Das B, Mehrdel B, Goodman D, Streicher M, Seo Y, Caravaca J. PMID: 41567575; PMCID: PMC12818914.
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Enhancing the Cherenkov over scintillation ratio using dichroic filters in BGO and TlCl for TOF-PET. Sci Rep. 2025 May 28; 15(1):18731.
Mehrdel B, Kratochwil N, Seo Y, Glodo J, Bhattacharya P, Ariño-Estrada G, Caravaca J. PMID: 40436952; PMCID: PMC12120110.
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Individual and Simultaneous Imaging of 99m Tc and 177Lu with a Preclinical Broad Energy-Spectrum CZT-based SPECT. IEEE Trans Radiat Plasma Med Sci. 2025 May; 9(5):564-577.
Encarnação PMCC, Correia PMM, Mehrdel B, Bredwell I, Veloso JFCA, Caravaca J, Seo Y. PMID: 40390772; PMCID: PMC12088624.
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A Technique to Quantify Very Low Activities in Regions of Interest With a Collimatorless Detector. IEEE Trans Med Imaging. 2024 08; 43(8):2745-2757.
Caravaca J, Bobba KN, Du S, Peter R, Gullberg GT, Bidkar AP, Flavell RR, Seo Y. PMID: 38478457; PMCID: PMC11293990.
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Animals
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A generalization of the maximum likelihood expectation maximization (MLEM) method: Masked-MLEM. Phys Med Biol. 2023 12 11; 68(24).
Zheng Y, Frame E, Caravaca J, Gullberg GT, Vetter K, Seo Y. PMID: 37918026; PMCID: PMC10819675.
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