Joachim Li, MD, PhD

Title(s)Professor, Microbiology and Immunology
SchoolSchool of Medicine
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    Yeast Chromosome Structure, Replication and Segregation
    NIH/NCI R13CA094910Jun 28, 2002 - Jun 27, 2003
    Role: Principal Investigator
    Role of regulation of eukaryotic DNA replication in preserving genome stability
    NIH/NIGMS R01GM059704Jul 1, 2000 - Apr 30, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bui DT, Li JJ. DNA Rereplication Is Susceptible to Nucleotide-Level Mutagenesis. Genetics. 2019 06; 212(2):445-460. PMID: 31028114.
      View in: PubMed
    2. Hanlon SL, Li JJ. Re-replication of a centromere induces chromosomal instability and aneuploidy. PLoS Genet. 2015 Apr; 11(4):e1005039. PMID: 25901968.
      View in: PubMed
    3. Richardson CD, Li JJ. Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements. PLoS Genet. 2014 Jun; 10(6):e1004358. PMID: 24945837.
      View in: PubMed
    4. Finn KJ, Li JJ. Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination. PLoS Genet. 2013; 9(1):e1003192. PMID: 23300490.
      View in: PubMed
    5. Green BM, Finn KJ, Li JJ. Loss of DNA replication control is a potent inducer of gene amplification. Science. 2010 Aug 20; 329(5994):943-6. PMID: 20724634.
      View in: PubMed
    6. Moses AM, Liku ME, Li JJ, Durbin R. Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites. Proc Natl Acad Sci U S A. 2007 Nov 06; 104(45):17713-8. PMID: 17978194.
      View in: PubMed
    7. Green BM, Morreale RJ, Ozaydin B, Derisi JL, Li JJ. Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant. Mol Biol Cell. 2006 May; 17(5):2401-14. PMID: 16481397.
      View in: PubMed
    8. Liku ME, Nguyen VQ, Rosales AW, Irie K, Li JJ. CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell. 2005 Oct; 16(10):5026-39. PMID: 16093348.
      View in: PubMed
    9. Green BM, Li JJ. Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage. Mol Biol Cell. 2005 Jan; 16(1):421-32. PMID: 15537702.
      View in: PubMed
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