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Joachim Li, MD, PhD

Title(s)Professor, Microbiology and Immunology
SchoolSchool of Medicine
Address600 16th Street
San Francisco CA 94158
Phone415-476-3841
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    Collapse Research 
    Collapse Research Activities and Funding
    Role of regulation of eukaryotic DNA replication in preserving genome stability
    NIH/NIGMS R01GM059704Dec 18, 2009 - Nov 30, 2011
    Role: Principal Investigator
    Yeast Chromosome Structure, Replication and Segregation
    NIH/NCI R13CA094910Jun 28, 2002 - Jun 27, 2003
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. DNA Rereplication Is Susceptible to Nucleotide-Level Mutagenesis. Genetics. 2019 06; 212(2):445-460. Bui DT, Li JJ. PMID: 31028114.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. Re-replication of a centromere induces chromosomal instability and aneuploidy. PLoS Genet. 2015 Apr; 11(4):e1005039. Hanlon SL, Li JJ. PMID: 25901968.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    3. Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements. PLoS Genet. 2014 Jun; 10(6):e1004358. Richardson CD, Li JJ. PMID: 24945837.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination. PLoS Genet. 2013; 9(1):e1003192. Finn KJ, Li JJ. PMID: 23300490.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    5. Loss of DNA replication control is a potent inducer of gene amplification. Science. 2010 Aug 20; 329(5994):943-6. Green BM, Finn KJ, Li JJ. PMID: 20724634.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    6. Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites. Proc Natl Acad Sci U S A. 2007 Nov 06; 104(45):17713-8. Moses AM, Liku ME, Li JJ, Durbin R. PMID: 17978194.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    7. Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant. Mol Biol Cell. 2006 May; 17(5):2401-14. Green BM, Morreale RJ, Ozaydin B, Derisi JL, Li JJ. PMID: 16481397.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    8. CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell. 2005 Oct; 16(10):5026-39. Liku ME, Nguyen VQ, Rosales AW, Irie K, Li JJ. PMID: 16093348.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    9. Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage. Mol Biol Cell. 2005 Jan; 16(1):421-32. Green BM, Li JJ. PMID: 15537702.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
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