John Vaughen, PhD

Title(s)Assistant Prof. Researcher, Anatomy
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #1326
San Francisco CA 94143
PronounsHe/Him/His
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    The lipidome remains a vast and poorly explored frontier that often goes awry in diseases like Parkinson's and Alzheimer's. We hope to gain genetic control over neural and glial lipidomes. How and why do select lipid species function in brain cells, including in synaptic vesicle fusion, lysosome catabolism, or glial ensheathment? We are excited to develop genetic tools to cell-type specifically track and manipulate the lipidome using the Drosophila brain as a tractable model.
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. From seconds to days: Neural plasticity viewed through a lipid lens. Curr Opin Neurobiol. 2023 Jun; 80:102702. Vaughen JP, Theisen E, Clandinin TR. PMID: 36965206.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    2. Glial control of sphingolipid levels sculpts diurnal remodeling in a circadian circuit. Neuron. 2022 Oct 05; 110(19):3186-3205.e7. Vaughen JP, Theisen E, Rivas-Serna IM, Berger AB, Kalakuntla P, Anreiter I, Mazurak VC, Rodriguez TP, Mast JD, Hartl T, Perlstein EO, Reimer RJ, Clandinin MT, Clandinin TR. PMID: 35961319; PMCID: PMC10868424.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    3. Cell Extrusion: A Stress-Responsive Force for Good or Evil in Epithelial Homeostasis. Dev Cell. 2018 02 26; 44(4):532. Ohsawa S, Vaughen J, Igaki T. PMID: 29486197.
      View in: PubMed   Mentions: 11     Fields:    
    4. Cell Extrusion: A Stress-Responsive Force for Good or Evil in Epithelial Homeostasis. Dev Cell. 2018 Feb 05; 44(3):284-296. Ohsawa S, Vaughen J, Igaki T. PMID: 29408235; PMCID: PMC6207186.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    5. Breaking Down Neighbors to Fuel Tumorigenesis. Dev Cell. 2017 Feb 06; 40(3):219-220. Vaughen J, Igaki T. PMID: 28171745; PMCID: PMC6207202.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Slit-Robo Repulsive Signaling Extrudes Tumorigenic Cells from Epithelia. Dev Cell. 2016 Dec 19; 39(6):683-695. Vaughen J, Igaki T. PMID: 27997825; PMCID: PMC6207184.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    7. Non-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesis. Cancer Sci. 2015 Dec; 106(12):1651-8. Enomoto M, Vaughen J, Igaki T. PMID: 26362609; PMCID: PMC4714670.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
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