Yuh Nung Jan, PhD

InstitutionUniversity of California San Francisco
Address1550 Fourth St
San Francisco CA 94158
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    Other Positions
    TitleHoward Hughes Investigator

    Collapse Research 
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    Dendrite morphogenesis, function and regeneration
    NIH R35NS097227Dec 1, 2016 - Nov 30, 2024
    Role: Principal Investigator
    Molecular mechanisms of dendrite development in mammalian CNS
    NIH R01MH084234Jan 1, 2004 - Jan 31, 2013
    Role: Principal Investigator
    Molecular Mechanisms of dendrite development in mammalia
    NIH R01NS047200Jan 1, 2004 - Dec 31, 2007
    Role: Principal Investigator
    Genetic Dissection of Dendrite Development
    NIH R37NS040929Jan 18, 2001 - Dec 31, 2016
    Role: Principal Investigator
    Genetic Dissection of Dendrite Development
    NIH R01NS040929Jan 18, 2001 - Nov 30, 2009
    Role: Principal Investigator
    NIH/NIMH P50MH048200Sep 1, 1991 - Aug 31, 2002
    Role: Co-Investigator
    NIH R01NS015757Dec 1, 1979 - Jun 30, 1988
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse In The News
    Collapse Featured Presentations

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Jan LY, Jan Y. Influences: Cold Spring Harbor summer courses and Drosophila melanogaster neurogenetics. J Gen Physiol. 2018 May 16. PMID: 29769227.
      View in: PubMed
    2. DeVault L, Li T, Izabel S, Thompson-Peer KL, Jan LY, Jan Y. Dendrite regeneration of adult Drosophila sensory neurons diminishes with aging and is inhibited by epidermal-derived matrix metalloproteinase 2. Genes Dev. 2018 Mar 01; 32(5-6):402-414. PMID: 29563183.
      View in: PubMed
    3. Jan Y, Jan LY. Force-activated ion channels in close-up. Nature. 2018 Feb 22; 554(7693):469-470. PMID: 29469134.
      View in: PubMed
    4. Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan Y, Grabe M, Jan LY. The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel. Neuron. 2018 Mar 07; 97(5):1063-1077.e4. PMID: 29478917.
      View in: PubMed
    5. Ye W, Han TW, Nassar LM, Zubia M, Jan Y, Jan LY. Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F. Proc Natl Acad Sci U S A. 2018 Feb 13; 115(7):E1667-E1674. PMID: 29382763.
      View in: PubMed
    6. Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan Y, Minor DL, Cheng Y, Jan LY. Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature. 2017 12 21; 552(7685):426-429. PMID: 29236684.
      View in: PubMed
    7. He M, Ye W, Wang WJ, Sison ES, Jan Y, Jan LY. Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis. Proc Natl Acad Sci U S A. 2017 Dec 26; 114(52):E11161-E11169. PMID: 29229864.
      View in: PubMed
    8. Deshpande A, Yadav S, Dao DQ, Wu ZY, Hokanson KC, Cahill MK, Wiita AP, Jan Y, Ullian EM, Weiss LA. Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. Cell Rep. 2017 Dec 05; 21(10):2678-2687. PMID: 29212016.
      View in: PubMed
    9. Meltzer S, Bagley JA, Perez GL, O'Brien CE, DeVault L, Guo Y, Jan LY, Jan Y. Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons. Cell Rep. 2017 Oct 24; 21(4):859-866. PMID: 29069593.
      View in: PubMed
    10. Orr BO, Gorczyca D, Younger MA, Jan LY, Jan Y, Davis GW. Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity. Cell Rep. 2017 Aug 22; 20(8):1855-1866. PMID: 28834749.
      View in: PubMed
    11. Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Cheng T, Jan LY, Jan Y, Cheng Y. Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature. 2017 07 06; 547(7661):118-122. PMID: 28658211.
      View in: PubMed
    12. Klassen MP, Peters CJ, Zhou S, Williams HH, Jan LY, Jan Y. Age-dependent diastolic heart failure in an in vivo Drosophila model. Elife. 2017 03 22; 6. PMID: 28328397.
      View in: PubMed
    13. Yadav S, Oses-Prieto JA, Peters CJ, Zhou J, Pleasure SJ, Burlingame AL, Jan LY, Jan Y. TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation. Neuron. 2017 Jan 18; 93(2):379-393. PMID: 28065648.
      View in: PubMed
    14. Li J, Zhang W, Guo Z, Wu S, Jan LY, Jan Y. A Defensive Kicking Behavior in Response to Mechanical Stimuli Mediated by Drosophila Wing Margin Bristles. J Neurosci. 2016 Nov 02; 36(44):11275-11282. PMID: 27807168.
      View in: PubMed
    15. Thayer DA, Yang SB, Jan Y, Jan LY. N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels. J Physiol. 2016 11 15; 594(22):6701-6713. PMID: 27377235.
      View in: PubMed
    16. Thompson-Peer KL, DeVault L, Li T, Jan LY, Jan Y. In vivo dendrite regeneration after injury is different from dendrite development. Genes Dev. 2016 08 01; 30(15):1776-89. PMID: 27542831; PMCID: PMC5002981 [Available on 02/01/17].
    17. Guo Y, Wang Y, Zhang W, Meltzer S, Zanini D, Yu Y, Li J, Cheng T, Guo Z, Wang Q, Jacobs JS, Sharma Y, Eberl DF, Göpfert MC, Jan LY, Jan Y, Wang Z. Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):7243-8. PMID: 27298354; PMCID: PMC4932980 [Available on 12/28/16].
    18. Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan Y. Phosphorylation of ß-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. 2016 05 04; 90(3):551-63. PMID: 27112495; PMCID: PMC4860041 [Available on 05/04/17].
    19. Meltzer S, Yadav S, Lee J, Soba P, Younger SH, Jin P, Zhang W, Parrish J, Jan LY, Jan Y. Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons. Neuron. 2016 Feb 17; 89(4):741-55. PMID: 26853303; PMCID: PMC4760923 [Available on 02/17/17].
    20. Yu D, Dong Z, Gustafson WC, Ruiz-González R, Signor L, Marzocca F, Borel F, Klassen MP, Makhijani K, Royant A, Jan Y, Weiss WA, Guo S, Shu X. Rational design of a monomeric and photostable far-red fluorescent protein for fluorescence imaging in vivo. Protein Sci. 2016 Feb; 25(2):308-15. PMID: 26549191; PMCID: PMC4815332 [Available on 02/01/17].
    21. Lin T, Pan PY, Lai YT, Chiang KW, Hsieh HL, Wu YP, Ke JM, Lee MC, Liao SS, Shih HT, Tang CY, Yang SB, Cheng HC, Wu JT, Jan Y, Lee HH. Spindle-F Is the Central Mediator of Ik2 Kinase-Dependent Dendrite Pruning in Drosophila Sensory Neurons. PLoS Genet. 2015 Nov; 11(11):e1005642. PMID: 26540204; PMCID: PMC4634852.
    22. Zhang W, Cheng LE, Kittelmann M, Li J, Petkovic M, Cheng T, Jin P, Guo Z, Göpfert MC, Jan LY, Jan Y. Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel. Cell. 2015 Sep 10; 162(6):1391-403. PMID: 26359990; PMCID: PMC4568062.
    23. Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan Y, Jan LY. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nat Neurosci. 2015 Sep; 18(9):1236-46. PMID: 26258683; PMCID: PMC4639927.
    24. Yu D, Baird MA, Allen JR, Howe ES, Klassen MP, Reade A, Makhijani K, Song Y, Liu S, Murthy Z, Zhang SQ, Weiner OD, Kornberg TB, Jan Y, Davidson MW, Shu X. A naturally monomeric infrared fluorescent protein for protein labeling in vivo. Nat Methods. 2015 Aug; 12(8):763-5. PMID: 26098020; PMCID: PMC4521985.
    25. Song Y, Sretavan D, Salegio EA, Berg J, Huang X, Cheng T, Xiong X, Meltzer S, Han C, Nguyen TT, Bresnahan JC, Beattie MS, Jan LY, Jan Y. Regulation of axon regeneration by the RNA repair and splicing pathway. Nat Neurosci. 2015 Jun; 18(6):817-25. PMID: 25961792; PMCID: PMC4446171.
    26. Soba P, Han C, Zheng Y, Perea D, Miguel-Aliaga I, Jan LY, Jan Y. The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion. Elife. 2015 Mar 12; 4. PMID: 25764303; PMCID: PMC4391025.
    27. Peters CJ, Yu H, Tien J, Jan Y, Li M, Jan LY. Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):3547-52. PMID: 25733897; PMCID: PMC4371966.
    28. To TL, Piggott BJ, Makhijani K, Yu D, Jan Y, Shu X. Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):3338-43. PMID: 25733847; PMCID: PMC4371907.
    29. Ultanir SK, Yadav S, Hertz NT, Oses-Prieto JA, Claxton S, Burlingame AL, Shokat KM, Jan LY, Jan Y. MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. Neuron. 2014 Dec 03; 84(5):968-82. PMID: 25456499; PMCID: PMC4407996.
    30. Gorczyca DA, Younger S, Meltzer S, Kim SE, Cheng L, Song W, Lee HY, Jan LY, Jan Y. Identification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila. Cell Rep. 2014 Nov 20; 9(4):1446-58. PMID: 25456135; PMCID: PMC4254518.
    31. Zhang W, Yan Z, Li B, Jan LY, Jan Y. Identification of motor neurons and a mechanosensitive sensory neuron in the defecation circuitry of Drosophila larvae. Elife. 2014 Oct 30; 3. PMID: 25358089; PMCID: PMC4244571.
    32. Bagley JA, Yan Z, Zhang W, Wildonger J, Jan LY, Jan Y. Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function. Genes Dev. 2014 Sep 01; 28(17):1940-56. PMID: 25184680; PMCID: PMC4197945.
    33. Tien J, Peters CJ, Wong XM, Cheng T, Jan Y, Jan LY, Yang H. A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 2014 Jun 30; 3. PMID: 24980701; PMCID: PMC4112547.
    34. Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan Y, Weiss WA, Shu X. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nat Commun. 2014 May 15; 5:3626. PMID: 24832154; PMCID: PMC4077998.
    35. Parrish JZ, Kim CC, Tang L, Bergquist S, Wang T, Derisi JL, Jan LY, Jan Y, Davis GW. Krüppel mediates the selective rebalancing of ion channel expression. Neuron. 2014 May 07; 82(3):537-44. PMID: 24811378; PMCID: PMC4104505.
    36. Rumpf S, Bagley JA, Thompson-Peer KL, Zhu S, Gorczyca D, Beckstead RB, Jan LY, Jan Y. Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7331-6. PMID: 24799714; PMCID: PMC4034197.
    37. Han C, Song Y, Xiao H, Wang D, Franc NC, Jan LY, Jan Y. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila. Neuron. 2014 Feb 05; 81(3):544-560. PMID: 24412417; PMCID: PMC3995171.
    38. Kim WJ, Jan LY, Jan Y. A PDF/NPF neuropeptide signaling circuitry of male Drosophila melanogaster controls rival-induced prolonged mating. Neuron. 2013 Dec 04; 80(5):1190-205. PMID: 24314729; PMCID: PMC3867312.
    39. Yuan Q, Song Y, Yang CH, Jan LY, Jan Y. Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila. Nat Neurosci. 2014 Jan; 17(1):81-8. PMID: 24241395; PMCID: PMC3995170.
    40. Wong XM, Younger S, Peters CJ, Jan Y, Jan LY. Subdued, a TMEM16 family Ca²?-activated Cl?channel in Drosophila melanogaster with an unexpected role in host defense. Elife. 2013 Nov 05; 2:e00862. PMID: 24192034; PMCID: PMC3814000.
    41. Zhang W, Yan Z, Jan LY, Jan Y. Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13612-7. PMID: 23898199; PMCID: PMC3746866.
    42. Huang F, Wang X, Ostertag EM, Nuwal T, Huang B, Jan Y, Basbaum AI, Jan LY. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nat Neurosci. 2013 Sep; 16(9):1284-90. PMID: 23872594; PMCID: PMC4034143.
    43. Tien J, Lee HY, Minor DL, Jan Y, Jan LY. Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6352-7. PMID: 23576756; PMCID: PMC3631655.
    44. Thayer DA, Jan Y, Jan LY. Increased neuronal activity fragments the Golgi complex. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1482-7. PMID: 23297202; PMCID: PMC3557034.
    45. Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y, Cheng LE, Meltzer S, Jan LY, Jan Y. Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature. 2013 Jan 10; 493(7431):221-5. PMID: 23222543; PMCID: PMC3917554.
    46. Ori-McKenney KM, Jan LY, Jan Y. Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons. Neuron. 2012 Dec 06; 76(5):921-30. PMID: 23217741; PMCID: PMC3523279.
    47. Yang H, Kim A, David T, Palmer D, Jin T, Tien J, Huang F, Cheng T, Coughlin SR, Jan Y, Jan LY. TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell. 2012 Sep 28; 151(1):111-22. PMID: 23021219; PMCID: PMC3582364.
    48. Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan Y, Jan LY, Rock JR. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16354-9. PMID: 22988107; PMCID: PMC3479591.
    49. Yang SB, Tien AC, Boddupalli G, Xu AW, Jan Y, Jan LY. Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron. 2012 Aug 09; 75(3):425-36. PMID: 22884327; PMCID: PMC3467009.
    50. Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, James CD, Rowitch DH, Shuman MA, Jan Y, Jan LY. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev. 2012 Aug 15; 26(16):1780-96. PMID: 22855790; PMCID: PMC3426758.
    51. Song Y, Ori-McKenney KM, Zheng Y, Han C, Jan LY, Jan Y. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes Dev. 2012 Jul 15; 26(14):1612-25. PMID: 22759636; PMCID: PMC3404388.
    52. Kim WJ, Jan LY, Jan Y. Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals. Nat Neurosci. 2012 Jun; 15(6):876-83. PMID: 22561453; PMCID: PMC3417086.
    53. Huang WC, Xiao S, Huang F, Harfe BD, Jan Y, Jan LY. Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron. 2012 Apr 12; 74(1):179-92. PMID: 22500639; PMCID: PMC3329964.
    54. Ge WP, Miyawaki A, Gage FH, Jan Y, Jan LY. Local generation of glia is a major astrocyte source in postnatal cortex. Nature. 2012 Mar 28; 484(7394):376-80. PMID: 22456708; PMCID: PMC3777276.
    55. Ultanir SK, Hertz NT, Li G, Ge WP, Burlingame AL, Pleasure SJ, Shokat KM, Jan LY, Jan Y. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron. 2012 Mar 22; 73(6):1127-42. PMID: 22445341; PMCID: PMC3333840.
    56. Jan LY, Jan Y. Voltage-gated potassium channels and the diversity of electrical signalling. J Physiol. 2012 Jun 01; 590(11):2591-9. PMID: 22431339; PMCID: PMC3424718.
    57. Yang SB, Mclemore KD, Tasic B, Luo L, Jan Y, Jan LY. Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers. J Physiol. 2012 Jun 01; 590(11):2645-58. PMID: 22411008; PMCID: PMC3424722.
    58. Jan Y. Yoshiki Hotta's influence. J Neurogenet. 2012 Mar; 26(1):3-4. PMID: 22263807.
      View in: PubMed
    59. Han C, Wang D, Soba P, Zhu S, Lin X, Jan LY, Jan Y. Integrins regulate repulsion-mediated dendritic patterning of drosophila sensory neurons by restricting dendrites in a 2D space. Neuron. 2012 Jan 12; 73(1):64-78. PMID: 22243747; PMCID: PMC3269260.
    60. Fieni F, Lee SB, Jan Y, Kirichok Y. Activity of the mitochondrial calcium uniporter varies greatly between tissues. Nat Commun. 2012; 3:1317. PMID: 23271651; PMCID: PMC3818247.
    61. Zhu S, Barshow S, Wildonger J, Jan LY, Jan Y. Ets transcription factor Pointed promotes the generation of intermediate neural progenitors in Drosophila larval brains. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20615-20. PMID: 22143802; PMCID: PMC3251047.
    62. Yang SB, Lee HY, Young DM, Tien AC, Rowson-Baldwin A, Shu YY, Jan Y, Jan LY. Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. J Mol Med (Berl). 2012 May; 90(5):575-85. PMID: 22105852; PMCID: PMC3354320.
    63. Lee HY, Ge WP, Huang W, He Y, Wang GX, Rowson-Baldwin A, Smith SJ, Jan Y, Jan LY. Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein. Neuron. 2011 Nov 17; 72(4):630-42. PMID: 22099464; PMCID: PMC3433402.
    64. Lee SB, Bagley JA, Lee HY, Jan LY, Jan Y. Pathogenic polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in Drosophila. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16795-800. PMID: 21930920; PMCID: PMC3189048.
    65. Yuan Q, Xiang Y, Yan Z, Han C, Jan LY, Jan Y. Light-induced structural and functional plasticity in Drosophila larval visual system. Science. 2011 Sep 09; 333(6048):1458-62. PMID: 21903815; PMCID: PMC4114502.
    66. Ouyang Y, Petritsch C, Wen H, Jan L, Jan Y, Lu B. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development. 2011 Jun; 138(11):2185-96. PMID: 21558368; PMCID: PMC3091490.
    67. Han C, Jan LY, Jan Y. Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila. Proc Natl Acad Sci U S A. 2011 Jun 07; 108(23):9673-8. PMID: 21606367; PMCID: PMC3111288.
    68. Ye B, Kim JH, Yang L, McLachlan I, Younger S, Jan LY, Jan Y. Differential regulation of dendritic and axonal development by the novel Krüppel-like factor Dar1. J Neurosci. 2011 Mar 02; 31(9):3309-19. PMID: 21368042; PMCID: PMC3086283.
    69. Rumpf S, Lee SB, Jan LY, Jan Y. Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1. Development. 2011 Mar; 138(6):1153-60. PMID: 21343367; PMCID: PMC3042870.
    70. Xiang Y, Yuan Q, Vogt N, Looger LL, Jan LY, Jan Y. Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature. 2010 Dec 16; 468(7326):921-6. PMID: 21068723; PMCID: PMC3026603.
    71. Cheng LE, Song W, Looger LL, Jan LY, Jan Y. The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron. 2010 Aug 12; 67(3):373-80. PMID: 20696376; PMCID: PMC2933178.
    72. Young DM, Schenk AK, Yang SB, Jan Y, Jan LY. Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11074-9. PMID: 20534473; PMCID: PMC2890736.
    73. Jan Y, Jan LY. Branching out: mechanisms of dendritic arborization. Nat Rev Neurosci. 2010 May; 11(5):316-28. PMID: 20404840; PMCID: PMC3079328.
    74. Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan Y, Jan LY. Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A. 2009 Dec 15; 106(50):21413-8. PMID: 19965375; PMCID: PMC2781737.
    75. Kim MD, Wen Y, Jan Y. Patterning and organization of motor neuron dendrites in the Drosophila larva. Dev Biol. 2009 Dec 15; 336(2):213-21. PMID: 19818341; PMCID: PMC2785125.
    76. Parrish JZ, Xu P, Kim CC, Jan LY, Jan Y. The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron. 2009 Sep 24; 63(6):788-802. PMID: 19778508; PMCID: PMC2772869.
    77. Bultje RS, Castaneda-Castellanos DR, Jan LY, Jan Y, Kriegstein AR, Shi SH. Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron. 2009 Jul 30; 63(2):189-202. PMID: 19640478; PMCID: PMC2736606.
    78. Lee HH, Jan LY, Jan Y. Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6363-8. PMID: 19329489; PMCID: PMC2661847.
    79. Yang CH, Rumpf S, Xiang Y, Gordon MD, Song W, Jan LY, Jan Y. Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron. 2009 Feb 26; 61(4):519-26. PMID: 19249273; PMCID: PMC2748846.
    80. Chung HJ, Ge WP, Qian X, Wiser O, Jan Y, Jan LY. G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):635-40. PMID: 19118199.
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    81. Chung HJ, Qian X, Ehlers M, Jan Y, Jan LY. Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):629-34. PMID: 19118198.
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    82. Ge WP, Zhou W, Luo Q, Jan LY, Jan Y. Dividing glial cells maintain differentiated properties including complex morphology and functional synapses. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):328-33. PMID: 19104058.
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    83. Schroeder BC, Cheng T, Jan Y, Jan LY. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell. 2008 Sep 19; 134(6):1019-29. PMID: 18805094; PMCID: PMC2651354.
    84. Wildonger J, Jan LY, Jan Y. The Tsc1-Tsc2 complex influences neuronal polarity by modulating TORC1 activity and SAD levels. Genes Dev. 2008 Sep 15; 22(18):2447-53. PMID: 18794342; PMCID: PMC2749676.
    85. Zheng Y, Wildonger J, Ye B, Zhang Y, Kita A, Younger SH, Zimmerman S, Jan LY, Jan Y. Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat Cell Biol. 2008 Oct; 10(10):1172-80. PMID: 18758451; PMCID: PMC2588425.
    86. Huang J, Zhou W, Watson AM, Jan Y, Hong Y. Efficient ends-out gene targeting in Drosophila. Genetics. 2008 Sep; 180(1):703-7. PMID: 18757917; PMCID: PMC2535722.
    87. Sokol NS, Xu P, Jan Y, Ambros V. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes Dev. 2008 Jun 15; 22(12):1591-6. PMID: 18559475; PMCID: PMC2428057.
    88. Yang CH, Belawat P, Hafen E, Jan LY, Jan Y. Drosophila egg-laying site selection as a system to study simple decision-making processes. Science. 2008 Mar 21; 319(5870):1679-83. PMID: 18356529; PMCID: PMC2581776.
    89. Jan Y, Jan L. Retrospective: Seymour Benzer (1921-2007). Science. 2008 Jan 04; 319(5859):45. PMID: 18174427.
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    90. Koo BK, Yoon MJ, Yoon KJ, Im SK, Kim YY, Kim CH, Suh PG, Jan Y, Kong YY. An obligatory role of mind bomb-1 in notch signaling of mammalian development. PLoS One. 2007 Nov 28; 2(11):e1221. PMID: 18043734; PMCID: PMC2082076.
    91. Haass FA, Jonikas M, Walter P, Weissman JS, Jan Y, Jan LY, Schuldiner M. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18079-84. PMID: 17989219; PMCID: PMC2084299.
    92. Ye B, Zhang Y, Song W, Younger SH, Jan LY, Jan Y. Growing dendrites and axons differ in their reliance on the secretory pathway. Cell. 2007 Aug 24; 130(4):717-29. PMID: 17719548; PMCID: PMC2020851.
    93. Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan Y, Rakic P, Sestan N. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul; 10(7):819-27. PMID: 17589506.
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    94. Soba P, Zhu S, Emoto K, Younger S, Yang SJ, Yu HH, Lee T, Jan LY, Jan Y. Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron. 2007 May 03; 54(3):403-16. PMID: 17481394; PMCID: PMC1963441.
    95. Parrish JZ, Emoto K, Jan LY, Jan Y. Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. Genes Dev. 2007 Apr 15; 21(8):956-72. PMID: 17437999; PMCID: PMC1847713.
    96. Song W, Onishi M, Jan LY, Jan Y. Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5199-204. PMID: 17360325; PMCID: PMC1820883.
    97. Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan Y, Jan LY. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell. 2007 Feb 09; 128(3):547-60. PMID: 17289573; PMCID: PMC1955433.
    98. Parrish JZ, Emoto K, Kim MD, Jan Y. Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields. Annu Rev Neurosci. 2007; 30:399-423. PMID: 17378766.
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    99. Grueber WB, Ye B, Yang CH, Younger S, Borden K, Jan LY, Jan Y. Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology. Development. 2007 Jan; 134(1):55-64. PMID: 17164414.
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    100. Grabe M, Lai HC, Jain M, Jan Y, Jan LY. Structure prediction for the down state of a potassium channel voltage sensor. Nature. 2007 Feb 01; 445(7127):550-3. PMID: 17187053.
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    101. Kuo CT, Mirzadeh Z, Soriano-Navarro M, Rasin M, Wang D, Shen J, Sestan N, Garcia-Verdugo J, Alvarez-Buylla A, Jan LY, Jan Y. Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell. 2006 Dec 15; 127(6):1253-64. PMID: 17174898; PMCID: PMC1876765.
    102. Gu C, Zhou W, Puthenveedu MA, Xu M, Jan Y, Jan LY. The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron. 2006 Dec 07; 52(5):803-16. PMID: 17145502.
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    103. Fay AJ, Qian X, Jan Y, Jan LY. SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17548-53. PMID: 17085590; PMCID: PMC1634413.
    104. Ye B, Zhang YW, Jan LY, Jan Y. The secretory pathway and neuron polarization. J Neurosci. 2006 Oct 18; 26(42):10631-2. PMID: 17050701.
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    105. Raab-Graham KF, Haddick PC, Jan Y, Jan LY. Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science. 2006 Oct 06; 314(5796):144-8. PMID: 17023663.
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    106. Kim MD, Jan LY, Jan Y. The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes Dev. 2006 Oct 15; 20(20):2806-19. PMID: 17015425; PMCID: PMC1619948.
    107. Grabe M, Bichet D, Qian X, Jan Y, Jan LY. K+ channel selectivity depends on kinetic as well as thermodynamic factors. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14361-6. PMID: 16983068; PMCID: PMC1570128.
    108. Bichet D, Grabe M, Jan Y, Jan LY. Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14355-60. PMID: 16983069; PMCID: PMC1570129.
    109. Emoto K, Parrish JZ, Jan LY, Jan Y. The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance. Nature. 2006 Sep 14; 443(7108):210-3. PMID: 16906135.
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    110. Kuo CT, Zhu S, Younger S, Jan LY, Jan Y. Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron. 2006 Aug 03; 51(3):283-90. PMID: 16880123.
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    111. Yu F, Kuo CT, Jan Y. Drosophila neuroblast asymmetric cell division: recent advances and implications for stem cell biology. Neuron. 2006 Jul 06; 51(1):13-20. PMID: 16815328.
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    112. Chung HJ, Jan Y, Jan LY. Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proc Natl Acad Sci U S A. 2006 Jun 06; 103(23):8870-5. PMID: 16735477; PMCID: PMC1472242.
    113. Sweeney NT, Brenman JE, Jan Y, Gao FB. The coiled-coil protein shrub controls neuronal morphogenesis in Drosophila. Curr Biol. 2006 May 23; 16(10):1006-11. PMID: 16713958.
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    114. Wiser O, Qian X, Ehlers M, Ja WW, Roberts RW, Reuveny E, Jan Y, Jan LY. Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN. Neuron. 2006 May 18; 50(4):561-73. PMID: 16701207.
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    115. Ye B, Jan Y. Visualizing the breaking of symmetry. Dev Cell. 2006 Apr; 10(4):411-2. PMID: 16580986.
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    116. Parrish JZ, Kim MD, Jan LY, Jan Y. Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev. 2006 Apr 01; 20(7):820-35. PMID: 16547170; PMCID: PMC1472285.
    117. Surti TS, Huang L, Jan Y, Jan LY, Cooper EC. Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels. Proc Natl Acad Sci U S A. 2005 Dec 06; 102(49):17828-33. PMID: 16319223; PMCID: PMC1297712.
    118. Huang CS, Shi SH, Ule J, Ruggiu M, Barker LA, Darnell RB, Jan Y, Jan LY. Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell. 2005 Oct 07; 123(1):105-18. PMID: 16213216.
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    119. Kuo CT, Jan LY, Jan Y. Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling. Proc Natl Acad Sci U S A. 2005 Oct 18; 102(42):15230-5. PMID: 16210248; PMCID: PMC1242853.
    120. Grueber WB, Yang CH, Ye B, Jan Y. The development of neuronal morphology in insects. Curr Biol. 2005 Sep 06; 15(17):R730-8. PMID: 16139206.
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    121. Kuo CT, Jan Y. The hand that rocks the spindle. Nat Cell Biol. 2005 Sep; 7(9):858-9. PMID: 16136185.
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    122. Lai HC, Grabe M, Jan Y, Jan LY. The S4 voltage sensor packs against the pore domain in the KAT1 voltage-gated potassium channel. Neuron. 2005 Aug 04; 47(3):395-406. PMID: 16055063.
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    123. He Y, Emoto K, Fang X, Ren N, Tian X, Jan Y, Adler PN. Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases. Mol Biol Cell. 2005 Sep; 16(9):4139-52. PMID: 15975907; PMCID: PMC1196325.
    124. Ionescu-Zanetti C, Shaw RM, Seo J, Jan Y, Jan LY, Lee LP. Mammalian electrophysiology on a microfluidic platform. Proc Natl Acad Sci U S A. 2005 Jun 28; 102(26):9112-7. PMID: 15967996; PMCID: PMC1166618.
    125. Roegiers F, Jan LY, Jan Y. Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell. 2005 Aug; 16(8):3480-7. PMID: 15901829; PMCID: PMC1182290.
    126. Lai EC, Roegiers F, Qin X, Jan Y, Rubin GM. The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development. 2005 May; 132(10):2319-32. PMID: 15829515.
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    127. Goldstein AY, Jan Y, Luo L. Function and regulation of Tumbleweed (RacGAP50C) in neuroblast proliferation and neuronal morphogenesis. Proc Natl Acad Sci U S A. 2005 Mar 08; 102(10):3834-9. PMID: 15738386; PMCID: PMC553341.
    128. Ye B, Jan Y. The cadherin superfamily and dendrite development. Trends Cell Biol. 2005 Feb; 15(2):64-7. PMID: 15695092.
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    129. Cohen BE, Pralle A, Yao X, Swaminath G, Gandhi CS, Jan Y, Kobilka BK, Isacoff EY, Jan LY. A fluorescent probe designed for studying protein conformational change. Proc Natl Acad Sci U S A. 2005 Jan 25; 102(4):965-70. PMID: 15657131; PMCID: PMC545863.
    130. Anderson AC, Kitchens EA, Chan SW, St Hill C, Jan Y, Zhong W, Robey EA. The Notch regulator Numb links the Notch and TCR signaling pathways. J Immunol. 2005 Jan 15; 174(2):890-7. PMID: 15634911.
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    131. Huang EJ, Li H, Tang AA, Wiggins AK, Neve RL, Zhong W, Jan LY, Jan Y. Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev. 2005 Jan 01; 19(1):138-51. PMID: 15598981; PMCID: PMC540232.
    132. Grabe M, Lecar H, Jan Y, Jan LY. A quantitative assessment of models for voltage-dependent gating of ion channels. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17640-5. PMID: 15591352; PMCID: PMC539724.
    133. He Y, Fang X, Emoto K, Jan Y, Adler PN. The tricornered Ser/Thr protein kinase is regulated by phosphorylation and interacts with furry during Drosophila wing hair development. Mol Biol Cell. 2005 Feb; 16(2):689-700. PMID: 15591127; PMCID: PMC545904.
    134. Shi SH, Cheng T, Jan LY, Jan Y. APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Curr Biol. 2004 Nov 23; 14(22):2025-32. PMID: 15556865.
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    135. Emoto K, He Y, Ye B, Grueber WB, Adler PN, Jan LY, Jan Y. Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons. Cell. 2004 Oct 15; 119(2):245-56. PMID: 15479641.
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    136. Shi SH, Cheng T, Jan LY, Jan Y. The immunoglobulin family member dendrite arborization and synapse maturation 1 (Dasm1) controls excitatory synapse maturation. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13346-51. PMID: 15340156; PMCID: PMC516569.
    137. Shi SH, Cox DN, Wang D, Jan LY, Jan Y. Control of dendrite arborization by an Ig family member, dendrite arborization and synapse maturation 1 (Dasm1). Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13341-5. PMID: 15340157; PMCID: PMC516568.
    138. Lin YF, Raab-Graham K, Jan Y, Jan LY. NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7799-804. PMID: 15136749; PMCID: PMC419686.
    139. Roegiers F, Jan Y. Asymmetric cell division. Curr Opin Cell Biol. 2004 Apr; 16(2):195-205. PMID: 15196564.
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    140. Bichet D, Lin YF, Ibarra CA, Huang CS, Yi BA, Jan Y, Jan LY. Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4441-6. PMID: 15070737; PMCID: PMC384766.
    141. Moore AW, Roegiers F, Jan LY, Jan Y. Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification. Genes Dev. 2004 Mar 15; 18(6):623-8. PMID: 15075290; PMCID: PMC387238.
    142. Ye B, Petritsch C, Clark IE, Gavis ER, Jan LY, Jan Y. Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr Biol. 2004 Feb 17; 14(4):314-21. PMID: 14972682.
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    143. Grueber WB, Jan Y. Dendritic development: lessons from Drosophila and related branches. Curr Opin Neurobiol. 2004 Feb; 14(1):74-82. PMID: 15018941.
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    144. McCarroll SA, Murphy CT, Zou S, Pletcher SD, Chin CS, Jan Y, Kenyon C, Bargmann CI, Li H. Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet. 2004 Feb; 36(2):197-204. PMID: 14730301.
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    145. Li HS, Wang D, Shen Q, Schonemann MD, Gorski JA, Jones KR, Temple S, Jan LY, Jan Y. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron. 2003 Dec 18; 40(6):1105-18. PMID: 14687546.
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    146. Hong Y, Ackerman L, Jan LY, Jan Y. Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12712-7. PMID: 14569003; PMCID: PMC240683.
    147. Jan Y, Jan LY. The control of dendrite development. Neuron. 2003 Oct 09; 40(2):229-42. PMID: 14556706.
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    148. Rothenberg ME, Jan Y. Cell biology: the hippo hypothesis. Nature. 2003 Oct 02; 425(6957):469-70. PMID: 14523431.
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    149. Sun Y, Kanekar SL, Vetter ML, Gorski S, Jan Y, Glaser T, Brown NL. Conserved and divergent functions of Drosophila atonal, amphibian, and mammalian Ath5 genes. Evol Dev. 2003 Sep-Oct; 5(5):532-41. PMID: 12950631; PMCID: PMC2262842.
    150. Rothenberg ME, Rogers SL, Vale RD, Jan LY, Jan Y. Drosophila pod-1 crosslinks both actin and microtubules and controls the targeting of axons. Neuron. 2003 Aug 28; 39(5):779-91. PMID: 12948445.
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    151. Gu C, Jan Y, Jan LY. A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels. Science. 2003 Aug 01; 301(5633):646-9. PMID: 12893943.
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    152. Jan Y. Yuh-Nung Jan. Curr Biol. 2003 May 13; 13(10):R378-9. PMID: 12747843.
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    153. Hu K, Huang CS, Jan Y, Jan LY. ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C. Neuron. 2003 May 08; 38(3):417-32. PMID: 12741989.
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    154. Abdelilah-Seyfried S, Cox DN, Jan Y. Bazooka is a permissive factor for the invasive behavior of discs large tumor cells in Drosophila ovarian follicular epithelia. Development. 2003 May; 130(9):1927-35. PMID: 12642496.
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    155. Justice N, Roegiers F, Jan LY, Jan Y. Lethal giant larvae acts together with numb in notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage. Curr Biol. 2003 Apr 29; 13(9):778-83. PMID: 12725738.
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    156. Grueber WB, Ye B, Moore AW, Jan LY, Jan Y. Dendrites of distinct classes of Drosophila sensory neurons show different capacities for homotypic repulsion. Curr Biol. 2003 Apr 15; 13(8):618-26. PMID: 12699617.
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    157. Justice NJ, Jan Y. A lethal giant kinase in cell polarity. Nat Cell Biol. 2003 Apr; 5(4):273-4. PMID: 12669072.
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    158. Grueber WB, Jan LY, Jan Y. Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. Cell. 2003 Mar 21; 112(6):805-18. PMID: 12654247.
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    159. Petritsch C, Tavosanis G, Turck CW, Jan LY, Jan Y. The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts. Dev Cell. 2003 Feb; 4(2):273-81. PMID: 12586070.
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    160. Shi SH, Jan LY, Jan Y. Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell. 2003 Jan 10; 112(1):63-75. PMID: 12526794.
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    161. Petersen PH, Zou K, Hwang JK, Jan Y, Zhong W. Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature. 2002 Oct 31; 419(6910):929-34. PMID: 12410312.
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    162. Shen Q, Zhong W, Jan Y, Temple S. Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts. Development. 2002 Oct; 129(20):4843-53. PMID: 12361975.
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    163. Donovan J, Kordylewska A, Jan Y, Utset MF. Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice. Curr Biol. 2002 Sep 17; 12(18):1605-10. PMID: 12372254.
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    164. Rothenberg ME, Jan Y. salvador--The persistence of proliferation. Cancer Cell. 2002 Sep; 2(3):171-3. PMID: 12242148.
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    165. Moore AW, Jan LY, Jan Y. hamlet, a binary genetic switch between single- and multiple- dendrite neuron morphology. Science. 2002 Aug 23; 297(5585):1355-8. PMID: 12193790.
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    166. Grueber WB, Jan LY, Jan Y. Tiling of the Drosophila epidermis by multidendritic sensory neurons. Development. 2002 Jun; 129(12):2867-78. PMID: 12050135.
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    167. Cohen BE, McAnaney TB, Park ES, Jan Y, Boxer SG, Jan LY. Probing protein electrostatics with a synthetic fluorescent amino acid. Science. 2002 May 31; 296(5573):1700-3. PMID: 12040199.
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    168. Ma D, Zerangue N, Raab-Graham K, Fried SR, Jan Y, Jan LY. Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron. 2002 Feb 28; 33(5):715-29. PMID: 11879649.
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    169. Justice NJ, Jan Y. Variations on the Notch pathway in neural development. Curr Opin Neurobiol. 2002 Feb; 12(1):64-70. PMID: 11861166.
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    170. Bodmer R, Jan LY, Jan Y. A late role for a subset of neurogenic genes to limit sensory precursor recruitments in Drosophila embryos. Roux Arch Dev Biol. 1993 Aug; 202(6):371-381. PMID: 28306050.
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    171. Giniger E, Wells W, Jan LY, Jan Y. Tracing neurons with a kinesin-ß-galactosidase fusion protein. Roux Arch Dev Biol. 1993 Mar; 202(2):112-122. PMID: 28305652.
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    172. Hartenstein V, Jan Y. Studying Drosophila embryogenesis with P-lacZ enhancer trap lines. Roux Arch Dev Biol. 1992 Jun; 201(4):194-220. PMID: 28305845.
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    173. Dambly-Chaudière C, Ghysen A, Jan LY, Jan Y. The determination of sense organs in Drosophila: interaction of scute with daughterless. Roux Arch Dev Biol. 1988 Dec; 197(7):419-423. PMID: 28305749.
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    174. Bodmer R, Jan Y. Morphological differentiation of the embryonic peripheral neurons in Drosophila. Roux Arch Dev Biol. 1987 Feb; 196(2):69-77. PMID: 28305460.
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