Joseph Geradts, MD, MA

Title(s)Professor, Pathology
SchoolSchool of Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant. Transl Oncol. 2024 Feb 26; 43:101907. Van Berckelaer C, Van Laere S, Lee S, Morse MA, Geradts J, Dirix L, Kockx M, Bertucci F, Van Dam P, Devi GR. PMID: 38412664; PMCID: PMC10907867.
      View in: PubMed   Mentions:
    2. Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation. Nat Commun. 2024 Feb 09; 15(1):1231. Kim WK, Buckley AJ, Lee DH, Hiroto A, Nenninger CH, Olson AW, Wang J, Li Z, Vikram R, Adzavon YM, Yau TY, Bao Y, Kahn M, Geradts J, Xiao GQ, Sun Z. PMID: 38336745; PMCID: PMC10858246.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Predicting early breast cancer recurrence from histopathological images in the Carolina Breast Cancer Study. NPJ Breast Cancer. 2023 Nov 11; 9(1):92. Shi Y, Olsson LT, Hoadley KA, Calhoun BC, Marron JS, Geradts J, Niethammer M, Troester MA. PMID: 37952058; PMCID: PMC10640636.
      View in: PubMed   Mentions:
    4. Growth Dynamics of Ductal Carcinoma in Situ Recapitulate Normal Breast Development. bioRxiv. 2023 Oct 02. Ryser MD, Greenwald MA, Sorribes IC, King LM, Hall A, Geradts J, Weaver DL, Mallo D, Holloway S, Monyak D, Gumbert G, Vaez-Ghaemi S, Wu E, Murgas K, Grimm LJ, Maley CC, Marks JR, Shibata D, Hwang ES. PMID: 37873488; PMCID: PMC10592867.
      View in: PubMed   Mentions:
    5. Differential distribution of actual and surrogate oncotype DX recurrence scores in breast cancer patients by age, menopausal status, race, and body mass index. Breast Cancer Res Treat. 2023 Oct; 201(3):447-460. Mohamed A, Olsson LT, Geradts J. PMID: 37453958.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Reproducibility and intratumoral heterogeneity of the PAM50 breast cancer assay. Breast Cancer Res Treat. 2023 May; 199(1):147-154. Hurson AN, Hamilton AM, Olsson LT, Kirk EL, Sherman ME, Calhoun BC, Geradts J, Troester MA. PMID: 36892725; PMCID: PMC10147733.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis. Nat Commun. 2022 11 02; 13(1):6552. Hiroto A, Kim WK, Pineda A, He Y, Lee DH, Le V, Olson AW, Aldahl J, Nenninger CH, Buckley AJ, Xiao GQ, Geradts J, Sun Z. PMID: 36323713; PMCID: PMC9630272.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    8. Pathobiologic Stratification of Oncotype DX Recurrence Scores and Comparative Validation of 3 Surrogate Models. Arch Pathol Lab Med. 2022 10 01; 146(10):1258-1267. Mohamed A, Kousar A, Wong J, Vohra N, Muzaffar M, Geradts J. PMID: 35119458.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma. Nat Commun. 2022 06 13; 13(1):3399. Rebbeck CA, Xian J, Bornelöv S, Geradts J, Hobeika A, Geiger H, Alvarez JF, Rozhkova E, Nicholls A, Robine N, Lyerly HK, Hannon GJ. PMID: 35697697; PMCID: PMC9192778.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    10. Correction: Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells. Oncogene. 2022 Feb; 41(8):1225-1226. Cao X, Geradts J, Dewhirst MW, Lo HW. PMID: 34887555.
      View in: PubMed   Mentions: 1     Fields:    
    11. JOINT AND INDIVIDUAL ANALYSIS OF BREAST CANCER HISTOLOGIC IMAGES AND GENOMIC COVARIATES. Ann Appl Stat. 2021 Dec; 15(4):1697-1722. Carmichael I, Calhoun BC, Hoadley KA, Troester MA, Geradts J, Couture HD, Olsson L, Perou CM, Niethammer M, Hannig J, Marron JS. PMID: 35432688; PMCID: PMC9007558.
      View in: PubMed   Mentions: 3  
    12. Race-Related Differences in the Clinical Presentation and Histopathologic Features of Phyllodes Tumor. Am Surg. 2023 Mar; 89(3):407-413. Johnson HM, Mohamed A, Hassan MM, Geradts J, Geisel L, Vohra NA, Wong JH. PMID: 34190619.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Expression of X-Linked Inhibitor of Apoptosis Protein (XIAP) in Breast Cancer Is Associated with Shorter Survival and Resistance to Chemotherapy. Cancers (Basel). 2021 Jun 04; 13(11). Devi GR, Finetti P, Morse MA, Lee S, de Nonneville A, Van Laere S, Troy J, Geradts J, McCall S, Bertucci F. PMID: 34199946; PMCID: PMC8200223.
      View in: PubMed   Mentions: 10  
    14. Spatiotemporal strategies to identify aggressive biology in precancerous breast biopsies. WIREs Mech Dis. 2021 03; 13(2):e1506. Frankhauser DE, Jovanovic-Talisman T, Lai L, Yee LD, Wang LV, Mahabal A, Geradts J, Rockne RC, Tomsic J, Jones V, Sistrunk C, Miranda-Carboni G, Dietze EC, Erhunmwunsee L, Hyslop T, Seewaldt VL. PMID: 33001587; PMCID: PMC8544796.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features. JNCI Cancer Spectr. 2021 Feb; 5(1). Benefield HC, Reeder-Hayes KE, Nichols HB, Calhoun BC, Love MI, Kirk EL, Geradts J, Hoadley KA, Cole SR, Earp HS, Olshan AF, Carey LA, Perou CM, Troester MA. PMID: 33442657; PMCID: PMC7791616.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    16. Quantitative assessment of distant recurrence risk in early stage breast cancer using a nonlinear combination of pathological, clinical and imaging variables. J Biophotonics. 2020 10; 13(10):e201960235. Nichols BS, Chelales E, Wang R, Schulman A, Gallagher J, Greenup RA, Geradts J, Harter J, Marcom PK, Wilke LG, Ramanujam N. PMID: 32573935; PMCID: PMC8521784.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Borderline Estrogen Receptor-Positive Breast Cancers in Black and White Women. J Natl Cancer Inst. 2020 07 01; 112(7):728-736. Benefield HC, Allott EH, Reeder-Hayes KE, Perou CM, Carey LA, Geradts J, Sun X, Calhoun BC, Troester MA. PMID: 31742342; PMCID: PMC7357313.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    18. Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis. Oncogene. 2020 04; 39(16):3276-3291. He Y, Mi J, Olson A, Aldahl J, Hooker E, Yu EJ, Le V, Lee DH, Kim WK, Robins DM, Geradts J, Sun Z. PMID: 32089544; PMCID: PMC7165053.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    19. Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer. Ann Oncol. 2020 05; 31(5):590-598. Waks AG, Cohen O, Kochupurakkal B, Kim D, Dunn CE, Buendia Buendia J, Wander S, Helvie K, Lloyd MR, Marini L, Hughes ME, Freeman SS, Ivy SP, Geradts J, Isakoff S, LoRusso P, Adalsteinsson VA, Tolaney SM, Matulonis U, Krop IE, D'Andrea AD, Winer EP, Lin NU, Shapiro GI, Wagle N. PMID: 32245699; PMCID: PMC7946408.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    20. DNA methylation markers predict recurrence-free interval in triple-negative breast cancer. NPJ Breast Cancer. 2020; 6:3. Fackler MJ, Cho S, Cope L, Gabrielson E, Visvanathan K, Wilsbach K, Meir-Levi D, Lynch CF, Marks J, Geradts J, Regan MM, Viale G, Wolff AC, Sukumar S, Umbricht CB. PMID: 32025567; PMCID: PMC6994477.
      View in: PubMed   Mentions: 9  
    21. Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration. PLoS Genet. 2020 01; 16(1):e1008588. Le V, He Y, Aldahl J, Hooker E, Yu EJ, Olson A, Kim WK, Lee DH, Wong M, Sheng R, Mi J, Geradts J, Cunha GR, Sun Z. PMID: 31929563; PMCID: PMC6980684.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    22. Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin-mediated prostatic tumorigenesis. J Biol Chem. 2020 01 10; 295(2):631-644. Aldahl J, Mi J, Pineda A, Kim WK, Olson A, Hooker E, He Y, Yu EJ, Le V, Lee DH, Geradts J, Sun Z. PMID: 31819003; PMCID: PMC6956540.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    23. The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression. PLoS Genet. 2019 10; 15(10):e1008451. Olson A, Le V, Aldahl J, Yu EJ, Hooker E, He Y, Lee DH, Kim WK, Cardiff RD, Geradts J, Sun Z. PMID: 31658259; PMCID: PMC6816545.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    24. Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications. Breast Cancer Res Treat. 2020 Jan; 179(1):185-195. Allott EH, Shan Y, Chen M, Sun X, Garcia-Recio S, Kirk EL, Olshan AF, Geradts J, Earp HS, Carey LA, Perou CM, Pfeiffer RM, Anderson WF, Troester MA. PMID: 31535320; PMCID: PMC6985047.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. Oncogene. 2019 09; 38(38):6507-6520. He Y, Johnson DT, Yang JS, Wu H, You S, Yoon J, Lee DH, Kim WK, Aldahl J, Le V, Hooker E, Yu EJ, Geradts J, Cardiff RD, Sun Z. PMID: 31358900; PMCID: PMC6752978.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    26. Mammographic density: intersection of advocacy, science, and clinical practice. Curr Breast Cancer Rep. 2019 09; 11(3):100-110. Tossas-Milligan K, Shalabi S, Jones V, Keely PJ, Conklin MW, Eliceiri KW, Winn R, Sistrunk C, Geradts J, Miranda-Carboni G, Dietze EC, Yee LD, Seewaldt VL. PMID: 33312342; PMCID: PMC7728377.
      View in: PubMed   Mentions: 1  
    27. CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer. Nat Commun. 2019 06 04; 10(1):2450. Racioppi L, Nelson ER, Huang W, Mukherjee D, Lawrence SA, Lento W, Masci AM, Jiao Y, Park S, York B, Liu Y, Baek AE, Drewry DH, Zuercher WJ, Bertani FR, Businaro L, Geradts J, Hall A, Means AR, Chao N, Chang CY, McDonnell DP. PMID: 31164648; PMCID: PMC6547743.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    28. Expression of tetraspanins NET-6 and CD151 in breast cancer as a potential tumor biomarker. Clin Exp Med. 2019 Aug; 19(3):377-384. Jiang L, Zhang X, Geradts J, Wei Q, Hochwald S, Xu H, Huang H. PMID: 31004251.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    29. Deletion of the p16INK4a tumor suppressor and expression of the androgen receptor induce sarcomatoid carcinomas with signet ring cells in the mouse prostate. PLoS One. 2019; 14(1):e0211153. Lee DH, Yu EJ, Aldahl J, Yang J, He Y, Hooker E, Le V, Mi J, Olson A, Wu H, Geradts J, Xiao GQ, Gonzalgo ML, Cardiff RD, Sun Z. PMID: 30677079; PMCID: PMC6345450.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    30. Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas. Cancer Causes Control. 2019 Jan; 30(1):31-39. Williams LA, Hoadley KA, Nichols HB, Geradts J, Perou CM, Love MI, Olshan AF, Troester MA. PMID: 30617775; PMCID: PMC6396692.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    31. Image analysis with deep learning to predict breast cancer grade, ER status, histologic subtype, and intrinsic subtype. NPJ Breast Cancer. 2018; 4:30. Couture HD, Williams LA, Geradts J, Nyante SJ, Butler EN, Marron JS, Perou CM, Troester MA, Niethammer M. PMID: 30182055; PMCID: PMC6120869.
      View in: PubMed   Mentions: 92  
    32. Circulating Biomarkers and Resistance to Endocrine Therapy in Metastatic Breast Cancers: Correlative Results from AZD9496 Oral SERD Phase I Trial. Clin Cancer Res. 2018 12 01; 24(23):5860-5872. Paoletti C, Schiavon G, Dolce EM, Darga EP, Carr TH, Geradts J, Hoch M, Klinowska T, Lindemann J, Marshall G, Morgan S, Patel P, Rowlands V, Sathiyayogan N, Aung K, Hamilton E, Patel M, Armstrong A, Jhaveri K, Im SA, Iqbal N, Butt F, Dive C, Harrington EA, Barrett JC, Baird R, Hayes DF. PMID: 30082476.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    33. Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proc Natl Acad Sci U S A. 2018 07 31; 115(31):7869-7878. Xiao T, Li W, Wang X, Xu H, Yang J, Wu Q, Huang Y, Geradts J, Jiang P, Fei T, Chi D, Zang C, Liao Q, Rennhack J, Andrechek E, Li N, Detre S, Dowsett M, Jeselsohn RM, Liu XS, Brown M. PMID: 29987050; PMCID: PMC6077722.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    34. TP53 protein levels, RNA-based pathway assessment, and race among invasive breast cancer cases. NPJ Breast Cancer. 2018; 4:13. Williams LA, Butler EN, Sun X, Allott EH, Cohen SM, Fuller AM, Hoadley KA, Perou CM, Geradts J, Olshan AF, Troester MA. PMID: 29951581; PMCID: PMC6018637.
      View in: PubMed   Mentions: 16  
    35. Differential cellular localization of CELSR2 and ING4 and correlations with hormone receptor status in breast cancer. Histol Histopathol. 2018 Aug; 33(8):835-842. Jiang L, Zhang X, Xiang C, Geradts J, Wei Q, Liang Y, Huang H, Xu JF. PMID: 29489009.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    36. Frequency of breast cancer subtypes among African American women in the AMBER consortium. Breast Cancer Res. 2018 02 06; 20(1):12. Allott EH, Geradts J, Cohen SM, Khoury T, Zirpoli GR, Bshara W, Davis W, Omilian A, Nair P, Ondracek RP, Cheng TD, Miller CR, Hwang H, Thorne LB, O'Connor S, Bethea TN, Bell ME, Hu Z, Li Y, Kirk EL, Sun X, Ruiz-Narvaez EA, Perou CM, Palmer JR, Olshan AF, Ambrosone CB, Troester MA. PMID: 29409530; PMCID: PMC5801839.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    37. Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study. J Natl Cancer Inst. 2018 02 01; 110(2). Troester MA, Sun X, Allott EH, Geradts J, Cohen SM, Tse CK, Kirk EL, Thorne LB, Mathews M, Li Y, Hu Z, Robinson WR, Hoadley KA, Olopade OI, Reeder-Hayes KE, Earp HS, Olshan AF, Carey LA, Perou CM. PMID: 28859290; PMCID: PMC6059138.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    38. XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype. Cancer Res. 2018 04 01; 78(7):1726-1738. Evans MK, Brown MC, Geradts J, Bao X, Robinson TJ, Jolly MK, Vermeulen PB, Palmer GM, Gromeier M, Levine H, Morse MA, Van Laere SJ, Devi GR. PMID: 29351901; PMCID: PMC7724565.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    39. Prediagnostic Smoking Is Associated with Binary and Quantitative Measures of ER Protein and ESR1 mRNA Expression in Breast Tumors. Cancer Epidemiol Biomarkers Prev. 2018 01; 27(1):67-74. Butler EN, Bensen JT, Chen M, Conway K, Richardson DB, Sun X, Geradts J, Olshan AF, Troester MA. PMID: 29133365; PMCID: PMC5760366.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    40. Reproductive risk factor associations with lobular and ductal carcinoma in the Carolina Breast Cancer Study. Cancer Causes Control. 2018 01; 29(1):25-32. Williams LA, Nichols HB, Hoadley KA, Tse CK, Geradts J, Bell ME, Perou CM, Love MI, Olshan AF, Troester MA. PMID: 29124544; PMCID: PMC5903274.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    41. Ki-67 Expression in Breast Cancer Tissue Microarrays: Assessing Tumor Heterogeneity, Concordance With Full Section, and Scoring Methods. Am J Clin Pathol. 2017 Aug 01; 148(2):108-118. Khoury T, Zirpoli G, Cohen SM, Geradts J, Omilian A, Davis W, Bshara W, Miller R, Mathews MM, Troester M, Palmer JR, Ambrosone CB. PMID: 28898983; PMCID: PMC5848430.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    42. Prostate-derived Ets factor, an oncogenic driver in breast cancer. Tumour Biol. 2017 May; 39(5):1010428317691688. Sood AK, Geradts J, Young J. PMID: 28468594.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    43. Miniature spectral imaging device for wide-field quantitative functional imaging of the morphological landscape of breast tumor margins. J Biomed Opt. 2017 02 01; 22(2):26007. Nichols BS, Llopis A, Palmer GM, McCachren SS, Senlik O, Miller D, Brooke MA, Jokerst NM, Geradts J, Greenup R, Ramanujam N. PMID: 28241273; PMCID: PMC5321165.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    44. CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer. Cancer Res. 2017 04 01; 77(7):1662-1673. Alfaqih MA, Nelson ER, Liu W, Safi R, Jasper JS, Macias E, Geradts J, Thompson JW, Dubois LG, Freeman MR, Chang CY, Chi JT, McDonnell DP, Freedland SJ. PMID: 28130224; PMCID: PMC5687884.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    45. Rational Manual and Automated Scoring Thresholds for the Immunohistochemical Detection of TP53 Missense Mutations in Human Breast Carcinomas. Appl Immunohistochem Mol Morphol. 2016 Jul; 24(6):398-404. Taylor NJ, Nikolaishvili-Feinberg N, Midkiff BR, Conway K, Millikan RC, Geradts J. PMID: 26200835; PMCID: PMC4716889.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    46. Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification. Breast Cancer Res. 2016 06 28; 18(1):68. Allott EH, Geradts J, Sun X, Cohen SM, Zirpoli GR, Khoury T, Bshara W, Chen M, Sherman ME, Palmer JR, Ambrosone CB, Olshan AF, Troester MA. PMID: 27349894; PMCID: PMC4924300.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    47. Inverse association between MDM2 and HUWE1 protein expression levels in human breast cancer and liposarcoma. Int J Clin Exp Pathol. 2016; 9(6):6342-6349. Canfield K, Wells W, Geradts J, Kinlaw WB, Cheng C, Kurokawa M. PMID: 29375730; PMCID: PMC5782804.
      View in: PubMed   Mentions: 9     Fields:    
    48. Correlation of breast tissue histology and optical signatures to improve margin assessment techniques. J Biomed Opt. 2016 06 01; 21(6):66014. Kennedy S, Caldwell M, Bydlon T, Mulvey C, Mueller J, Wilke L, Barry W, Ramanujam N, Geradts J. PMID: 27327487; PMCID: PMC4914603.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    49. Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS). Breast Cancer Res Treat. 2016 06; 157(3):447-59. Geradts J, Groth J, Wu Y, Jin G. PMID: 27250000.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    50. Rapid staining and imaging of subnuclear features to differentiate between malignant and benign breast tissues at a point-of-care setting. J Cancer Res Clin Oncol. 2016 Jul; 142(7):1475-86. Mueller JL, Gallagher JE, Chitalia R, Krieger M, Erkanli A, Willett RM, Geradts J, Ramanujam N. PMID: 27106032; PMCID: PMC4900949.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    51. Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium. Cancer Epidemiol Biomarkers Prev. 2016 Mar; 25(3):470-8. Allott EH, Cohen SM, Geradts J, Sun X, Khoury T, Bshara W, Zirpoli GR, Miller CR, Hwang H, Thorne LB, O'Connor S, Tse CK, Bell MB, Hu Z, Li Y, Kirk EL, Bethea TN, Perou CM, Palmer JR, Ambrosone CB, Olshan AF, Troester MA. PMID: 26711328; PMCID: PMC4779705.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    52. FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target. Radiat Res. 2015 Nov; 184(5):456-69. Horton JK, Siamakpour-Reihani S, Lee CT, Zhou Y, Chen W, Geradts J, Fels DR, Hoang P, Ashcraft KA, Groth J, Kung HN, Dewhirst MW, Chi JT. PMID: 26488758; PMCID: PMC4671819.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsCTClinical Trials
    53. CHAMBER: A Regional Performance Improvement CME Initiative for Breast Cancer Health Care Providers. J Natl Compr Canc Netw. 2015 Aug; 13(8):1005-11. Sutton LM, Geradts J, Hamilton EP, Havlin KA, Kimmick GG, Marcom PK, Spector NL, Watson M, Rabin DU, Bruno TO, Noe A, Miller S, Subramaniam C, Layton S, Grichnik K. PMID: 26285246.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance. Breast Cancer Res. 2015 Jul 04; 17:91. Li S, Payne S, Wang F, Claus P, Su Z, Groth J, Geradts J, de Ridder G, Alvarez R, Marcom PK, Pizzo SV, Bachelder RE. PMID: 26141457; PMCID: PMC4491247.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    55. A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins. PLoS One. 2015; 10(6):e0127525. Nichols BS, Schindler CE, Brown JQ, Wilke LG, Mulvey CS, Krieger MS, Gallagher J, Geradts J, Greenup RA, Von Windheim JA, Ramanujam N. PMID: 26076123; PMCID: PMC4468201.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    56. A quantitative microscopic approach to predict local recurrence based on in vivo intraoperative imaging of sarcoma tumor margins. Int J Cancer. 2015 Nov 15; 137(10):2403-12. Mueller JL, Fu HL, Mito JK, Whitley MJ, Chitalia R, Erkanli A, Dodd L, Cardona DM, Geradts J, Willett RM, Kirsch DG, Ramanujam N. PMID: 25994353; PMCID: PMC4575838.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    57. Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers. Int J Radiat Oncol Biol Phys. 2015 Jul 15; 92(4):846-55. Horton JK, Blitzblau RC, Yoo S, Geradts J, Chang Z, Baker JA, Georgiade GS, Chen W, Siamakpour-Reihani S, Wang C, Broadwater G, Groth J, Palta M, Dewhirst M, Barry WT, Duffy EA, Chi JT, Hwang ES. PMID: 26104938; PMCID: PMC4481883.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    58. DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival. Breast Cancer Res. 2014 Oct 07; 16(5):450. Conway K, Edmiston SN, May R, Kuan PF, Chu H, Bryant C, Tse CK, Swift-Scanlan T, Geradts J, Troester MA, Millikan RC. PMID: 25287138; PMCID: PMC4303129.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    59. A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype. Breast Cancer Res. 2014 Jul 25; 16(4):407. Cheng Q, Chang JT, Gwin WR, Zhu J, Ambs S, Geradts J, Lyerly HK. PMID: 25060555; PMCID: PMC4187325.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    60. Automated, quantitative analysis of histopathological staining in nuclei. AMIA Jt Summits Transl Sci Proc. 2014; 2014:54-9. Henao R, Geradts J, Kurokawa M, Kornbluth S, Lucas JE. PMID: 25717401; PMCID: PMC4333705.
      View in: PubMed   Mentions:
    61. 27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology. Science. 2013 Nov 29; 342(6162):1094-8. Nelson ER, Wardell SE, Jasper JS, Park S, Suchindran S, Howe MK, Carver NJ, Pillai RV, Sullivan PM, Sondhi V, Umetani M, Geradts J, McDonnell DP. PMID: 24288332; PMCID: PMC3899689.
      View in: PubMed   Mentions: 352     Fields:    Translation:HumansAnimalsCells
    62. αB-crystallin: a novel regulator of breast cancer metastasis to the brain. Clin Cancer Res. 2014 Jan 01; 20(1):56-67. Malin D, Strekalova E, Petrovic V, Deal AM, Al Ahmad A, Adamo B, Miller CR, Ugolkov A, Livasy C, Fritchie K, Hamilton E, Blackwell K, Geradts J, Ewend M, Carey L, Shusta EV, Anders CK, Cryns VL. PMID: 24132917; PMCID: PMC3973485.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    63. Optical spectral surveillance of breast tissue landscapes for detection of residual disease in breast tumor margins. PLoS One. 2013; 8(7):e69906. Brown JQ, Bydlon TM, Kennedy SA, Caldwell ML, Gallagher JE, Junker M, Wilke LG, Barry WT, Geradts J, Ramanujam N. PMID: 23922850; PMCID: PMC3724737.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    64. Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins. PLoS One. 2013; 8(6):e66198. Mueller JL, Harmany ZT, Mito JK, Kennedy SA, Kim Y, Dodd L, Geradts J, Kirsch DG, Willett RM, Brown JQ, Ramanujam N. PMID: 23824589; PMCID: PMC3688889.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    65. A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53. Sci Signal. 2013 May 07; 6(274):ra32. Kurokawa M, Kim J, Geradts J, Matsuura K, Liu L, Ran X, Xia W, Ribar TJ, Henao R, Dewhirst MW, Kim WJ, Lucas JE, Wang S, Spector NL, Kornbluth S. PMID: 23652204; PMCID: PMC3770270.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    66. Multidisciplinary care of patients with early-stage breast cancer. Surg Oncol Clin N Am. 2013 Apr; 22(2):299-317. Lyman GH, Baker J, Geradts J, Horton J, Kimmick G, Peppercorn J, Pruitt S, Scheri RP, Hwang ES. PMID: 23453336.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    67. Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast. PLoS One. 2012; 7(12):e51418. Bydlon TM, Barry WT, Kennedy SA, Brown JQ, Gallagher JE, Wilke LG, Geradts J, Ramanujam N. PMID: 23251526; PMCID: PMC3519619.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    68. Differential copy number aberrations in novel candidate genes associated with progression from in situ to invasive ductal carcinoma of the breast. Genes Chromosomes Cancer. 2012 Dec; 51(12):1067-78. Liao S, Desouki MM, Gaile DP, Shepherd L, Nowak NJ, Conroy J, Barry WT, Geradts J. PMID: 22887771; PMCID: PMC3465468.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    69. Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer. Breast Cancer Res. 2012 Apr 17; 14(2):R62. Cheng Q, Chang JT, Geradts J, Neckers LM, Haystead T, Spector NL, Lyerly HK. PMID: 22510516; PMCID: PMC3446397.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    70. Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases. Breast Cancer Res. 2011; 13(6):R125. Adamo B, Deal AM, Burrows E, Geradts J, Hamilton E, Blackwell KL, Livasy C, Fritchie K, Prat A, Harrell JC, Ewend MG, Carey LA, Miller CR, Anders CK. PMID: 22132754; PMCID: PMC3326567.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    71. PDEF in prostate cancer. Prostate. 2012 May 01; 72(6):592-6. Sood AK, Kim H, Geradts J. PMID: 21796651.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    72. Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells. Oncogene. 2012 Jan 05; 31(1):104-15. Cao X, Geradts J, Dewhirst MW, Lo HW. PMID: 21666711; PMCID: PMC3175334.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    73. Endobronchial metastatic breast cancer with pagetoid histology mimicking bronchial pagetoid squamous cell carcinoma in situ. Hum Pathol. 2011 Nov; 42(11):1819-22. West D, Geradts J, Wahidi M, Roggli V. PMID: 21663936.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    74. The genomic relationship between primary breast carcinomas and their nodal metastases. Cancer Invest. 2011 May; 29(4):300-7. Desouki MM, Liao S, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J. PMID: 21469979.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    75. Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas. Hum Pathol. 2011 Aug; 42(8):1125-31. Geradts J, de Herreros AG, Su Z, Burchette J, Broadwater G, Bachelder RE. PMID: 21315410; PMCID: PMC3315281.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    76. Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data. Cancer Epidemiol Biomarkers Prev. 2011 Mar; 20(3):476-82. Pilie PG, Ibarra-Drendall C, Troch MM, Broadwater G, Barry WT, Petricoin EF, Wulfkuhle JD, Liotta LA, Lem S, Baker JC, Stouder A, Ford AC, Wilke LG, Zalles CM, Mehta P, Williams J, Shivraj M, Su Z, Geradts J, Yu D, Seewaldt VL. PMID: 21242333; PMCID: PMC3051011.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    77. Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study. Clin Cancer Res. 2010 Dec 15; 16(24):6100-10. O'Brien KM, Cole SR, Tse CK, Perou CM, Carey LA, Foulkes WD, Dressler LG, Geradts J, Millikan RC. PMID: 21169259; PMCID: PMC3029098.
      View in: PubMed   Mentions: 202     Fields:    Translation:Humans
    78. Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast. Breast Cancer Res. 2010; 12(6):R91. Kennedy S, Geradts J, Bydlon T, Brown JQ, Gallagher J, Junker M, Barry W, Ramanujam N, Wilke L. PMID: 21054873; PMCID: PMC3046432.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    79. The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features. Cancer Invest. 2010 Nov; 28(9):969-77. Geradts J, Bean SM, Bentley RC, Barry WT. PMID: 20873988.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    80. Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach. J Cancer Res Clin Oncol. 2011 May; 137(5):795-809. Desouki MM, Liao S, Huang H, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J. PMID: 20680643.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    81. Histiocytoid carcinoma of the male breast. Ann Diagn Pathol. 2011 Jun; 15(3):190-3. Hutchinson CB, Geradts J. PMID: 20952293.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    82. Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins. Opt Express. 2010 Apr 12; 18(8):8058-76. Bydlon TM, Kennedy SA, Richards LM, Brown JQ, Yu B, Junker MK, Gallagher J, Geradts J, Wilke LG, Ramanujam N. PMID: 20588651; PMCID: PMC2939901.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    83. Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome. J Clin Oncol. 2010 May 01; 28(13):2198-206. Barry WT, Kernagis DN, Dressman HK, Griffis RJ, Hunter JD, Olson JA, Marks JR, Ginsburg GS, Marcom PK, Nevins JR, Geradts J, Datto MB. PMID: 20368555; PMCID: PMC2860437.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    84. Optical assessment of tumor resection margins in the breast. IEEE J Sel Top Quantum Electron. 2010 Mar 01; 16(3):530-544. Brown JQ, Bydlon TM, Richards LM, Yu B, Kennedy SA, Geradts J, Wilke LG, Junker M, Gallagher J, Barry W, Ramanujam N. PMID: 21544237; PMCID: PMC3085495.
      View in: PubMed   Mentions: 34  
    85. Rapid noninvasive optical imaging of tissue composition in breast tumor margins. Am J Surg. 2009 Oct; 198(4):566-74. Wilke LG, Brown JQ, Bydlon TM, Kennedy SA, Richards LM, Junker MK, Gallagher J, Barry WT, Geradts J, Ramanujam N. PMID: 19800470; PMCID: PMC2764289.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCTClinical Trials
    86. Sam-pointed domain containing Ets transcription factor in luminal breast cancer pathogenesis. Cancer Epidemiol Biomarkers Prev. 2009 Jun; 18(6):1899-903. Sood AK, Wang J, Mhawech-Fauceglia P, Jana B, Liang P, Geradts J. PMID: 19505923.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    87. Re: KAI1/CD82 is a novel target of estrogen receptor-mediated gene repression and downregulated in primary human breast cancer (Int J Cancer 123: 2239-2246, 2008). Int J Cancer. 2009 May 01; 124(9):2243-4; author reply 2245. Geradts J. PMID: 19115215.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    88. Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo. Cancer Res. 2009 Apr 01; 69(7):2919-26. Brown JQ, Wilke LG, Geradts J, Kennedy SA, Palmer GM, Ramanujam N. PMID: 19293184; PMCID: PMC2677720.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    89. Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:6554-6. Ramanujam N, Brown J, Bydlon TM, Kennedy SA, Richards LM, Junker MK, Gallagher J, Barry WT, Wilke LG, Geradts J. PMID: 19964903.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    90. Co-expression of urokinase with haptoglobin in human carcinomas. J Surg Res. 2009 Apr; 152(2):189-97. Harvey S, Kohga S, Sait SN, Markus G, Hurd TC, Martinick M, Geradts J, Saxena R, Gibbs JF. PMID: 19101688.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    91. Epidemiology of basal-like breast cancer. Breast Cancer Res Treat. 2008 May; 109(1):123-39. Millikan RC, Newman B, Tse CK, Moorman PG, Conway K, Dressler LG, Smith LV, Labbok MH, Geradts J, Bensen JT, Jackson S, Nyante S, Livasy C, Carey L, Earp HS, Perou CM. PMID: 17578664; PMCID: PMC2443103.
      View in: PubMed   Mentions: 448     Fields:    Translation:Humans
    92. hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands. Mol Cancer. 2007 Jun 05; 6:37. Desouki MM, Geradts J, Milon B, Franklin RB, Costello LC. PMID: 17550612; PMCID: PMC1892035.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    93. Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression. Hum Pathol. 2007 Nov; 38(11):1628-38. Sood AK, Saxena R, Groth J, Desouki MM, Cheewakriangkrai C, Rodabaugh KJ, Kasyapa CS, Geradts J. PMID: 17521701; PMCID: PMC2121591.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    94. The tetraspanin superfamily member NET-6 is a new tumor suppressor gene. J Cancer Res Clin Oncol. 2007 Oct; 133(10):761-9. Huang H, Sossey-Alaoui K, Beachy SH, Geradts J. PMID: 17486367.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    95. Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. Breast Cancer Res Treat. 2007 Jul; 103(3):283-91. Heller G, Geradts J, Ziegler B, Newsham I, Filipits M, Markis-Ritzinger EM, Kandioler D, Berger W, Stiglbauer W, Depisch D, Pirker R, Zielinski CC, Zöchbauer-Müller S. PMID: 17260099.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    96. Akt expression may predict favorable prognosis in cholangiocarcinoma. J Gastroenterol Hepatol. 2006 Nov; 21(11):1744-51. Javle MM, Yu J, Khoury T, Chadha KS, Chadha KC, Iyer RV, Foster J, Kuvshinoff BW, Gibbs JF, Geradts J, Black JD, Brattain MG. PMID: 16984600.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    97. Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer. BMC Cancer. 2006 Aug 01; 6:203. Yang J, Ramnath N, Moysich KB, Asch HL, Swede H, Alrawi SJ, Huberman J, Geradts J, Brooks JS, Tan D. PMID: 16882345; PMCID: PMC1555597.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    98. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA. 2006 Jun 07; 295(21):2492-502. Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K, Karaca G, Troester MA, Tse CK, Edmiston S, Deming SL, Geradts J, Cheang MC, Nielsen TO, Moorman PG, Earp HS, Millikan RC. PMID: 16757721.
      View in: PubMed   Mentions: 1667     Fields:    Translation:Humans
    99. Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer. Am J Clin Oncol. 2005 Dec; 28(6):560-4. Watwe V, Javle M, Lawrence D, Groth J, Iyer R, El-Hajjar D, Geradts J. PMID: 16317264.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    100. An unusual cause of cholecystitis? Am J Clin Oncol. 2005 Oct; 28(5):529-30. Bush E, Geradts J, O'Connor T. PMID: 16199997.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    101. High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype. Mod Pathol. 2005 Oct; 18(10):1289-94. Lark AL, Livasy CA, Dressler L, Moore DT, Millikan RC, Geradts J, Iacocca M, Cowan D, Little D, Craven RJ, Cance W. PMID: 15861214.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    102. Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York. Br J Cancer. 2005 Sep 19; 93(6):699-708. Varma G, Varma R, Huang H, Pryshchepava A, Groth J, Fleming D, Nowak NJ, McQuaid D, Conroy J, Mahoney M, Moysich K, Falkner KL, Geradts J. PMID: 16222315; PMCID: PMC2361621.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    103. Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation. Oncogene. 2005 Sep 15; 24(41):6249-55. Zöchbauer-Müller S, Fong KM, Geradts J, Xu X, Seidl S, End-Pfützenreuter A, Lang G, Heller G, Zielinski CC, Gazdar AF, Minna JD. PMID: 15940253.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    104. The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study. Breast Cancer Res. 2005; 7(6):R871-80. Conway K, Parrish E, Edmiston SN, Tolbert D, Tse CK, Geradts J, Livasy CA, Singh H, Newman B, Millikan RC. PMID: 16280033; PMCID: PMC1410768.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    105. Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis. Gene. 2005 Jul 18; 354:140-6. Singh KK, Kulawiec M, Still I, Desouki MM, Geradts J, Matsui S. PMID: 15979824.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    106. Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. Clin Cancer Res. 2005 Jun 15; 11(12):4357-64. Huang H, Groth J, Sossey-Alaoui K, Hawthorn L, Beall S, Geradts J. PMID: 15958618.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    107. Molecular prediction of recurrence of breast cancer. N Engl J Med. 2005 Apr 14; 352(15):1605-7; author reply 1605-7. Geradts J. PMID: 15829546.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    108. Prognostic significance of gelsolin expression level and variability in non-small cell lung cancer. Lung Cancer. 2004 Oct; 46(1):29-42. Yang J, Tan D, Asch HL, Swede H, Bepler G, Geradts J, Moysich KB. PMID: 15364130.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    109. Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma. J Gastrointest Surg. 2004 May-Jun; 8(4):448-53. Wilkinson NW, Black JD, Roukhadze E, Driscoll D, Smiley S, Hoshi H, Geradts J, Javle M, Brattain M. PMID: 15120370.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    110. Microtome shaving radiography: demonstration of loss of mammographic microcalcifications during histologic sectioning. Breast J. 2004 May-Jun; 10(3):200-3. Winston JS, Geradts J, Liu DF, Stomper PC. PMID: 15125745.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    111. Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays. Clin Cancer Res. 2003 Dec 01; 9(16 Pt 1):5988-95. Maitra A, Hansel DE, Argani P, Ashfaq R, Rahman A, Naji A, Deng S, Geradts J, Hawthorne L, House MG, Yeo CJ. PMID: 14676124.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    112. Mammographic predictors of the presence and size of invasive carcinomas associated with malignant microcalcification lesions without a mass. AJR Am J Roentgenol. 2003 Dec; 181(6):1679-84. Stomper PC, Geradts J, Edge SB, Levine EG. PMID: 14627596.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    113. p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis. Am J Surg Pathol. 2003 Dec; 27(12):1495-501. Rosty C, Geradts J, Sato N, Wilentz RE, Roberts H, Sohn T, Cameron JL, Yeo CJ, Hruban RH, Goggins M. PMID: 14657708.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    114. Reproductive factors in relation to breast cancer characterized by p53 protein expression (United States). Cancer Causes Control. 2003 Sep; 14(7):609-18. Furberg H, Millikan RC, Geradts J, Gammon MD, Dressler LG, Ambrosone CB, Newman B. PMID: 14575358.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    115. Identification of novel cellular targets in biliary tract cancers using global gene expression technology. Am J Pathol. 2003 07; 163(1):217-29. Hansel DE, Rahman A, Hidalgo M, Thuluvath PJ, Lillemoe KD, Schulick R, Ku JL, Park JG, Miyazaki K, Ashfaq R, Wistuba II, Varma R, Hawthorne L, Geradts J, Argani P, Maitra A. PMID: 12819026; PMCID: PMC1868162.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    116. HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites. Breast Cancer Res Treat. 2003 Jun; 79(3):355-64. Millikan R, Eaton A, Worley K, Biscocho L, Hodgson E, Huang WY, Geradts J, Iacocca M, Cowan D, Conway K, Dressler L. PMID: 12846420.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    117. Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions. Mod Pathol. 2003 Apr; 16(4):299-308. Parwani AV, Geradts J, Caspers E, Offerhaus GJ, Yeo CJ, Cameron JL, Klimstra DS, Maitra A, Hruban RH, Argani P. PMID: 12692194.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    118. Carcinoma of the esophagus with mixed basaloid squamous and glandular differentiation: a distinct histological presentation. Int J Gastrointest Cancer. 2003; 34(2-3):139-42. Bhagat V, Javle M, Geradts J. PMID: 15361648.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    119. CDKN2A promoter methylation in gastric adenocarcinomas: clinical variables. Hum Pathol. 2002 Dec; 33(12):1200-4. Vo QN, Geradts J, Boudreau DA, Bravo JC, Schneider BG. PMID: 12514789.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    120. Environmental factors in relation to breast cancer characterized by p53 protein expression. Cancer Epidemiol Biomarkers Prev. 2002 Sep; 11(9):829-35. Furberg H, Millikan RC, Geradts J, Gammon MD, Dressler LG, Ambrosone CB, Newman B. PMID: 12223426.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    121. Prevalence and spectrum of p53 mutations associated with smoking in breast cancer. Cancer Res. 2002 Apr 01; 62(7):1987-95. Conway K, Edmiston SN, Cui L, Drouin SS, Pang J, He M, Tse CK, Geradts J, Dressler L, Liu ET, Millikan R, Newman B. PMID: 11929815.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    122. Immunohistochemical [corrected] detection of the alternate INK4a-encoded tumor suppressor protein p14(ARF) in archival human cancers and cell lines using commercial antibodies: correlation with p16(INK4a) expression. Mod Pathol. 2001 Nov; 14(11):1162-8. Geradts J, Wilentz RE, Roberts H. PMID: 11706079.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    123. Ductal epithelial proliferations of the breast: a biological continuum? Comparative genomic hybridization and high-molecular-weight cytokeratin expression patterns. J Pathol. 2001 Nov; 195(4):415-21. Boecker W, Buerger H, Schmitz K, Ellis IA, van Diest PJ, Sinn HP, Geradts J, Diallo R, Poremba C, Herbst H. PMID: 11745672.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    124. 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer. Cancer Res. 2001 May 01; 61(9):3581-5. Zöchbauer-Müller S, Fong KM, Maitra A, Lam S, Geradts J, Ashfaq R, Virmani AK, Milchgrub S, Gazdar AF, Minna JD. PMID: 11325823.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    125. Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas. Int J Cancer. 2001 Jan 20; 95(1):34-8. Maitra A, Roberts H, Weinberg AG, Geradts J. PMID: 11241308.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    126. Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia. Cancer Detect Prev. 2001; 25(2):123-31. Creager AJ, Cohen JA, Geradts J. PMID: 11341347.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    127. Abnormal expression of cell cycle regulatory proteins in ductal and lobular carcinomas of the breast. Mod Pathol. 2000 Sep; 13(9):945-53. Geradts J, Ingram CD. PMID: 11007034.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    128. Two identical triplet sisters carrying a germline BRCA1 gene mutation acquire very similar breast cancer somatic mutations at multiple other sites throughout the genome. Genes Chromosomes Cancer. 2000 Aug; 28(4):359-69. Wistuba II, Tomlinson GE, Behrens C, Virmani A, Geradts J, Blum JL, Minna JD, Gazdar AF. PMID: 10862044.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    129. p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma. Gynecol Oncol. 2000 Jun; 77(3):439-45. Schmitz MJ, Hendricks DT, Farley J, Taylor RR, Geradts J, Rose GS, Birrer MJ. PMID: 10831356.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    130. Genomic FHIT analysis in RER+ and RER- adenocarcinomas of the pancreas. Genes Chromosomes Cancer. 2000 Mar; 27(3):239-43. Hilgers W, Groot Koerkamp B, Geradts J, Tang DJ, Yeo CJ, Hruban RH, Kern SE. PMID: 10679912.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    131. Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene. A comparison of four commercial antibodies. Appl Immunohistochem Mol Morphol. 2000 Mar; 8(1):71-9. Geradts J, Hruban RH, Schutte M, Kern SE, Maynard R. PMID: 10937052.
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    132. Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features. Br J Cancer. 2000 Mar; 82(6):1191-7. Geradts J, Fong KM, Zimmerman PV, Minna JD. PMID: 10735505; PMCID: PMC2363352.
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    133. Human breast cancer specimens: diffraction-enhanced imaging with histologic correlation--improved conspicuity of lesion detail compared with digital radiography. Radiology. 2000 Mar; 214(3):895-901. Pisano ED, Johnston RE, Chapman D, Geradts J, Iacocca MV, Livasy CA, Washburn DB, Sayers DE, Zhong Z, Kiss MZ, Thomlinson WC. PMID: 10715065.
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    134. Loss of p16/CDKN2A tumor suppressor protein in gastric adenocarcinoma is associated with Epstein-Barr virus and anatomic location in the body of the stomach. Hum Pathol. 2000 Jan; 31(1):45-50. Schneider BG, Gulley ML, Eagan P, Bravo JC, Mera R, Geradts J. PMID: 10665912.
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    135. Loss of KAI1 expression in the progression of colorectal cancer. Cancer Res. 1999 Nov 15; 59(22):5724-31. Lombardi DP, Geradts J, Foley JF, Chiao C, Lamb PW, Barrett JC. PMID: 10582691.
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    136. Estrogen receptor status, determined by immunohistochemistry, as a predictor of the recurrence of stage I endometrial carcinoma. Cancer. 1999 Nov 15; 86(10):2083-9. Gehrig PA, Van Le L, Olatidoye B, Geradts J. PMID: 10570435.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    137. Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: the UNC SPORE experience. University of North Carolina Specialized Program of Research Excellence. Breast Cancer Res Treat. 1999 Nov; 58(1):31-9. Dressler LG, Geradts J, Burroughs M, Cowan D, Millikan RC, Newman B. PMID: 10634516.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    138. Abnormal Fhit expression in malignant and premalignant lesions of the cervix. Cancer Res. 1999 Oct 15; 59(20):5270-4. Birrer MJ, Hendricks D, Farley J, Sundborg MJ, Bonome T, Walts MJ, Geradts J. PMID: 10537308.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    139. The 100-kDa proteolytic fragment of RB is retained predominantly within the nuclear compartment of apoptotic cells. Mol Cell Biol Res Commun. 1999 Jun; 1(3):216-20. Chen WD, Geradts J, Keane MM, Lipkowitz S, Zajac-Kaye M, Kaye FJ. PMID: 10425229.
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    140. G1 checkpoint protein and p53 abnormalities occur in most invasive transitional cell carcinomas of the urinary bladder. Br J Cancer. 1999 Jun; 80(8):1175-84. Niehans GA, Kratzke RA, Froberg MK, Aeppli DM, Nguyen PL, Geradts J. PMID: 10376969; PMCID: PMC2362363.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    141. Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues. Am J Pathol. 1999 Jun; 154(6):1665-71. Geradts J, Maynard R, Birrer MJ, Hendricks D, Abbondanzo SL, Fong KM, Barrett JC, Lombardi DP. PMID: 10362791; PMCID: PMC1866631.
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    142. Correlation of abnormal RB, p16ink4a, and p53 expression with 3p loss of heterozygosity, other genetic abnormalities, and clinical features in 103 primary non-small cell lung cancers. Clin Cancer Res. 1999 Apr; 5(4):791-800. Geradts J, Fong KM, Zimmerman PV, Maynard R, Minna JD. PMID: 10213214.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCellsCTClinical Trials
    143. Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expression. Cancer Res. 1998 Oct 15; 58(20):4740-4. Wilentz RE, Geradts J, Maynard R, Offerhaus GJ, Kang M, Goggins M, Yeo CJ, Kern SE, Hruban RH. PMID: 9788631.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    144. RET cooperates with RB/p53 inactivation in a somatic multi-step model for murine thyroid cancer. Oncogene. 1998 Sep 24; 17(12):1625-8. Coxon AB, Ward JM, Geradts J, Otterson GA, Zajac-Kaye M, Kaye FJ. PMID: 9794240.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    145. Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression. Oncogene. 1998 Jun 18; 16(24):3087-95. Frizelle SP, Grim J, Zhou J, Gupta P, Curiel DT, Geradts J, Kratzke RA. PMID: 9671387.
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    146. Loss of tumor suppressor gene expression in high-grade but not low-grade non-Hodgkin's lymphomas. Am J Clin Pathol. 1998 Jun; 109(6):669-74. Geradts J, Andriko JW, Abbondanzo SL. PMID: 9620022.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    147. Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product. Am J Pathol. 1998 Apr; 152(4):865-9. Gulley ML, Nicholls JM, Schneider BG, Amin MB, Ro JY, Geradts J. PMID: 9546345; PMCID: PMC1858242.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    148. Protein expression and functional analysis of the FHIT gene in human tumor cells. J Natl Cancer Inst. 1998 Mar 18; 90(6):426-32. Otterson GA, Xiao GH, Geradts J, Jin F, Chen WD, Niklinska W, Kaye FJ, Yeung RS. PMID: 9521166.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    149. Loss of RB and MTS1/CDKN2 (p16) expression in human sarcomas. Hum Pathol. 1997 Aug; 28(8):893-8. Cohen JA, Geradts J. PMID: 9269824.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    150. Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. Cancer Res. 1997 Aug 01; 57(15):3126-30. Schutte M, Hruban RH, Geradts J, Maynard R, Hilgers W, Rabindran SK, Moskaluk CA, Hahn SA, Schwarte-Waldhoff I, Schmiegel W, Baylin SB, Kern SE, Herman JG. PMID: 9242437.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansCells
    151. Molecular characterization of adenocarcinoma of the cervix. Gynecol Oncol. 1997 Feb; 64(2):242-51. Parker MF, Arroyo GF, Geradts J, Sabichi AL, Park RC, Taylor RR, Birrer MJ. PMID: 9038270.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    152. Rb and p16INK4a expression in resected non-small cell lung tumors. Cancer Res. 1996 Aug 01; 56(15):3415-20. Kratzke RA, Greatens TM, Rubins JB, Maddaus MA, Niewoehner DE, Niehans GA, Geradts J. PMID: 8758904.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    153. High frequency of aberrant p16(INK4A) expression in human breast cancer. Am J Pathol. 1996 Jul; 149(1):15-20. Geradts J, Wilson PA. PMID: 8686738; PMCID: PMC1865226.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    154. Wild-type and mutant retinoblastoma protein in paraffin sections. Mod Pathol. 1996 Mar; 9(3):339-47. Geradts J, Kratzke RA, Crush-Stanton S, Wen SF, Lincoln CE. PMID: 8685238.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    155. Molecular and immunochemical analyses of RB1 and cyclin D1 in human ductal pancreatic carcinomas and cell lines. Mol Carcinog. 1996 Feb; 15(2):85-95. Huang L, Lang D, Geradts J, Obara T, Klein-Szanto AJ, Lynch HT, Ruggeri BA. PMID: 8599583.
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    156. Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma. J Natl Cancer Inst. 1995 Dec 20; 87(24):1870-5. Kratzke RA, Otterson GA, Lincoln CE, Ewing S, Oie H, Geradts J, Kaye FJ. PMID: 7494231.
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    157. Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors: correlation with retinoblastoma protein expression. Cancer Res. 1995 Dec 15; 55(24):6006-11. Geradts J, Kratzke RA, Niehans GA, Lincoln CE. PMID: 8521382.
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    158. The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology. Breast Cancer Res Treat. 1995 Jul; 35(1):51-60. Newman B, Moorman PG, Millikan R, Qaqish BF, Geradts J, Aldrich TE, Liu ET. PMID: 7612904.
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    159. The need for epidemiologic studies of in-situ carcinoma of the breast. Breast Cancer Res Treat. 1995 Jul; 35(1):65-77. Millikan R, Dressler L, Geradts J, Graham M. PMID: 7612906.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    160. Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti-RB antibodies. Int J Cancer. 1994 Jul 15; 58(2):161-7. Geradts J, Hu SX, Lincoln CE, Benedict WF, Xu HJ. PMID: 8026875.
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    161. Pathology and laboratory medicine. JAMA. 1994 Jun 01; 271(21):1700-1. Geradts J, McLendon WW. PMID: 8182860.
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    162. Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors. Oncogene. 1994 May; 9(5):1321-6. Kratzke RA, Otterson GA, Hogg A, Coxon AB, Geradts J, Cowell JK, Kaye FJ. PMID: 8152792.
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    163. Retinoblastoma protein monoclonal antibodies with novel characteristics. J Immunol Methods. 1994 Mar 10; 169(2):231-40. Wen SF, Nodelman M, Nared-Hood K, Duncan J, Geradts J, Shepard HM. PMID: 7510760.
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    164. Human lung cancer cell lines exhibit resistance to retinoic acid treatment. Cell Growth Differ. 1993 Oct; 4(10):799-809. Geradts J, Chen JY, Russell EK, Yankaskas JR, Nieves L, Minna JD. PMID: 8274449.
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    165. RB-mediated tumor suppression of a lung cancer cell line is abrogated by an extract enriched in extracellular matrix. Cell Growth Differ. 1993 Aug; 4(8):629-35. Kratzke RA, Shimizu E, Geradts J, Gerster JL, Segal S, Otterson GA, Kaye FJ. PMID: 8398904.
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    166. Use of the polymerase chain reaction in the diagnosis of unsuspected herpes simplex viral pneumonia: report of a case. Hum Pathol. 1990 Jan; 21(1):118-21. Geradts J, Warnock M, Yen TS. PMID: 2153098.
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    167. Second international workshop on monoclonal antibodies and breast cancer. San Francisco, November 20-21, 1986. Breast Cancer Res Treat. 1987 Oct; 10(1):55-63. Ceriani RL, Geradts J, Peterson JA. PMID: 3689984.
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    168. Heterogeneity in the hormonal responsiveness of clones derived from the 13762NF rat mammary tumor. Cancer Res. 1986 Apr; 46(4 Pt 2):1920-7. Geradts J, Richards J, Edery M, Pang K, Larson L, Nandi S. PMID: 3004710.
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