Konstantinos Chiotis, MD, PhD

Title(s)Postdoctoral Scholar, Neurology
SchoolSchool of Medicine
Address185 Berry Street Bldg B, #378
San Francisco CA 94158
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ORCID ORCID Icon0000-0002-5679-0297 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach. Methods Mol Biol. 2024; 2785:195-218. Rodriguez-Vieitez E, Kumar A, Malarte ML, Ioannou K, Rocha FM, Chiotis K. PMID: 38427196.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Tracking reactive astrogliosis in autosomal dominant and sporadic Alzheimer's disease with multi-modal PET and plasma GFAP. Mol Neurodegener. 2023 09 12; 18(1):60. Chiotis K, Johansson C, Rodriguez-Vieitez E, Ashton NJ, Blennow K, Zetterberg H, Graff C, Nordberg A. PMID: 37697307; PMCID: PMC10496408.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Profiling of plasma biomarkers in the context of memory assessment in a tertiary memory clinic. Transl Psychiatry. 2023 07 25; 13(1):268. Bucci M, Bluma M, Savitcheva I, Ashton NJ, Chiotis K, Matton A, Kivipelto M, Di Molfetta G, Blennow K, Zetterberg H, Nordberg A. PMID: 37491358; PMCID: PMC10368630.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Astrocyte Signature in Alzheimer's Disease Continuum through a Multi-PET Tracer Imaging Perspective. Cells. 2023 05 24; 12(11). Fontana IC, Scarpa M, Malarte ML, Rocha FM, Ausellé-Bosch S, Bluma M, Bucci M, Chiotis K, Kumar A, Nordberg A. PMID: 37296589; PMCID: PMC10253101.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Blood β-synuclein is related to amyloid PET positivity in memory clinic patients. Alzheimers Dement. 2023 11; 19(11):4896-4907. Oeckl P, Bluma M, Bucci M, Halbgebauer S, Chiotis K, Sandebring-Matton A, Ashton NJ, Molfetta GD, Grötschel L, Kivipelto M, Blennow K, Zetterberg H, Savitcheva I, Nordberg A, Otto M. PMID: 37052206.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Crossover of Work Engagement: The Moderating Role of Agreeableness. Int J Environ Res Public Health. 2022 06 22; 19(13). Chiotis K, Michaelides G. PMID: 35805281; PMCID: PMC9265874.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Correction to: The Strategic Biomarker Roadmap for the validation of Alzheimer's diagnostic biomarkers: methodological update. Eur J Nucl Med Mol Imaging. 2021 Dec; 48(13):4525-4531. Boccardi M, Dodich A, Albanese E, Gayet-Ageron A, Festari C, Ashton NJ, Bischof GN, Chiotis K, Leuzy A, Wolters EE, Walter M, Rabinovici GD, Carrillo M, Drzezga A, Hansson O, Nordberg A, Ossenkoppele R, Villemagne VL, Winblad B, Frisoni G, Garibotto V. PMID: 34546388; PMCID: PMC9172693.
      View in: PubMed   Mentions:    Fields:    
    8. Alzheimer's disease profiled by fluid and imaging markers: tau PET best predicts cognitive decline. Mol Psychiatry. 2021 10; 26(10):5888-5898. Bucci M, Chiotis K, Nordberg A, Alzheimer’s Disease Neuroimaging Initiative. PMID: 34593971; PMCID: PMC8758489.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    9. Clinical validity of increased cortical binding of tau ligands of the THK family and PBB3 on PET as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework. Eur J Nucl Med Mol Imaging. 2021 07; 48(7):2086-2096. Chiotis K, Dodich A, Boccardi M, Festari C, Drzezga A, Hansson O, Ossenkoppele R, Frisoni G, Garibotto V, Nordberg A. PMID: 33723628; PMCID: PMC8175292.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. The strategic biomarker roadmap for the validation of Alzheimer's diagnostic biomarkers: methodological update. Eur J Nucl Med Mol Imaging. 2021 07; 48(7):2070-2085. Boccardi M, Dodich A, Albanese E, Gayet-Ageron A, Festari C, Ashton NJ, Bischof GN, Chiotis K, Leuzy A, Wolters EE, Walter MA, Rabinovici GD, Carrillo M, Drzezga A, Hansson O, Nordberg A, Ossenkoppele R, Villemagne VL, Winblad B, Frisoni GB, Garibotto V. PMID: 33688996; PMCID: PMC8175304.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    11. Assessment of Tau Pathology as Measured by 18F-THK5317 and 18F-Flortaucipir PET and Their Relation to Brain Atrophy and Cognition in Alzheimer's Disease. J Alzheimers Dis. 2021; 84(1):103-117. Colato E, Chiotis K, Ferreira D, Mazrina MS, Lemoine L, Mohanty R, Westman E, Nordberg A, Rodriguez-Vieitez E, Alzheimer’s Disease Neuroimaging Initiative. PMID: 34511502; PMCID: PMC8609906.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Regional Disconnection in Alzheimer Dementia and Amyloid-Positive Mild Cognitive Impairment: Association Between EEG Functional Connectivity and Brain Glucose Metabolism. Brain Connect. 2020 12; 10(10):555-565. Smailovic U, Koenig T, Savitcheva I, Chiotis K, Nordberg A, Blennow K, Winblad B, Jelic V. PMID: 33073602; PMCID: PMC7757561.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    13. Comparison of subtyping methods for neuroimaging studies in Alzheimer's disease: a call for harmonization. Brain Commun. 2020; 2(2):fcaa192. Mohanty R, Mårtensson G, Poulakis K, Muehlboeck JS, Rodriguez-Vieitez E, Chiotis K, Grothe MJ, Nordberg A, Ferreira D, Westman E. PMID: 33305264; PMCID: PMC7713995.
      View in: PubMed   Mentions: 12  
    14. [18F]THK5317 imaging as a tool for predicting prospective cognitive decline in Alzheimer's disease. Mol Psychiatry. 2021 10; 26(10):5875-5887. Chiotis K, Savitcheva I, Poulakis K, Saint-Aubert L, Wall A, Antoni G, Nordberg A. PMID: 32616831; PMCID: PMC8758479.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. Cross-interaction of tau PET tracers with monoamine oxidase B: evidence from in silico modelling and in vivo imaging. Eur J Nucl Med Mol Imaging. 2019 Jun; 46(6):1369-1382. Murugan NA, Chiotis K, Rodriguez-Vieitez E, Lemoine L, Ågren H, Nordberg A. PMID: 30919054; PMCID: PMC6486902.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    16. Clinical impact of [18F]flutemetamol PET among memory clinic patients with an unclear diagnosis. Eur J Nucl Med Mol Imaging. 2019 Jun; 46(6):1276-1286. Leuzy A, Savitcheva I, Chiotis K, Lilja J, Andersen P, Bogdanovic N, Jelic V, Nordberg A. PMID: 30915522; PMCID: PMC6486908.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    17. Optimal timing of tau pathology imaging and automatic extraction of a reference region using dynamic [18F]THK5317 PET. Neuroimage Clin. 2019; 22:101681. Jonasson M, Wall A, Chiotis K, Leuzy A, Eriksson J, Antoni G, Nordberg A, Lubberink M. PMID: 30710871; PMCID: PMC6357848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Tau PET imaging in neurodegenerative tauopathies-still a challenge. Mol Psychiatry. 2019 08; 24(8):1112-1134. Leuzy A, Chiotis K, Lemoine L, Gillberg PG, Almkvist O, Rodriguez-Vieitez E, Nordberg A. PMID: 30635637; PMCID: PMC6756230.
      View in: PubMed   Mentions: 230     Fields:    Translation:Humans
    19. Longitudinal tau and metabolic PET imaging in relation to novel CSF tau measures in Alzheimer's disease. Eur J Nucl Med Mol Imaging. 2019 May; 46(5):1152-1163. Leuzy A, Cicognola C, Chiotis K, Saint-Aubert L, Lemoine L, Andreasen N, Zetterberg H, Ye K, Blennow K, Höglund K, Nordberg A. PMID: 30610252; PMCID: PMC6451715.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    20. Longitudinal association between astrocyte function and glucose metabolism in autosomal dominant Alzheimer's disease. Eur J Nucl Med Mol Imaging. 2019 02; 46(2):348-356. Carter SF, Chiotis K, Nordberg A, Rodriguez-Vieitez E. PMID: 30515545; PMCID: PMC6333721.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    21. Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ species. Neuroimage Clin. 2018; 20:603-610. Oliveira F, Leuzy A, Castelhano J, Chiotis K, Hasselbalch SG, Rinne J, Mendonça A, Otto M, Lleó A, Santana I, Johansson J, Anderl-Straub S, Arnim C, Beer A, Blesa R, Fortea J, Sanna-Kaisa H, Portelius E, Pannee J, Zetterberg H, Blennow K, Moreira AP, Abrunhosa A, Nordberg A, Castelo-Branco M. PMID: 30186764; PMCID: PMC6120605.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    22. Spatial Normalization of 18F-Flutemetamol PET Images Using an Adaptive Principal-Component Template J Nucl Med. 2019 02 01; 60(2):285-291. Lilja J, Leuzy A, Chiotis K, Savitcheva I, Sörensen J, Nordberg A. PMID: 29903930; PMCID: PMC8833851.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    23. Dual tracer tau PET imaging reveals different molecular targets for 11C-THK5351 and 11C-PBB3 in the Alzheimer brain. Eur J Nucl Med Mol Imaging. 2018 07; 45(9):1605-1617. Chiotis K, Stenkrona P, Almkvist O, Stepanov V, Ferreira D, Arakawa R, Takano A, Westman E, Varrone A, Okamura N, Shimada H, Higuchi M, Halldin C, Nordberg A. PMID: 29752516; PMCID: PMC6061462.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    24. Tau positron emission tomography imaging in tauopathies: The added hurdle of off-target binding. Alzheimers Dement (Amst). 2018; 10:232-236. Lemoine L, Leuzy A, Chiotis K, Rodriguez-Vieitez E, Nordberg A. PMID: 29780868; PMCID: PMC5956931.
      View in: PubMed   Mentions: 51  
    25. Longitudinal uncoupling of cerebral perfusion, glucose metabolism, and tau deposition in Alzheimer's disease. Alzheimers Dement. 2018 05; 14(5):652-663. Leuzy A, Rodriguez-Vieitez E, Saint-Aubert L, Chiotis K, Almkvist O, Savitcheva I, Jonasson M, Lubberink M, Wall A, Antoni G, Nordberg A. PMID: 29268078.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    26. Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers. Lancet Neurol. 2017 08; 16(8):661-676. Frisoni GB, Boccardi M, Barkhof F, Blennow K, Cappa S, Chiotis K, Démonet JF, Garibotto V, Giannakopoulos P, Gietl A, Hansson O, Herholz K, Jack CR, Nobili F, Nordberg A, Snyder HM, Ten Kate M, Varrone A, Albanese E, Becker S, Bossuyt P, Carrillo MC, Cerami C, Dubois B, Gallo V, Giacobini E, Gold G, Hurst S, Lönneborg A, Lovblad KO, Mattsson N, Molinuevo JL, Monsch AU, Mosimann U, Padovani A, Picco A, Porteri C, Ratib O, Saint-Aubert L, Scerri C, Scheltens P, Schott JM, Sonni I, Teipel S, Vineis P, Visser PJ, Yasui Y, Winblad B. PMID: 28721928.
      View in: PubMed   Mentions: 229     Fields:    Translation:Humans
    27. Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework. Neurobiol Aging. 2017 04; 52:214-227. Chiotis K, Saint-Aubert L, Boccardi M, Gietl A, Picco A, Varrone A, Garibotto V, Herholz K, Nobili F, Nordberg A, Geneva Task Force for the Roadmap of Alzheimer's Biomarkers. PMID: 28317650.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    28. Tau PET imaging: present and future directions. Mol Neurodegener. 2017 02 20; 12(1):19. Saint-Aubert L, Lemoine L, Chiotis K, Leuzy A, Rodriguez-Vieitez E, Nordberg A. PMID: 28219440; PMCID: PMC5319037.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimals
    29. A Cross-Validation of FDG- and Amyloid-PET Biomarkers in Mild Cognitive Impairment for the Risk Prediction to Dementia due to Alzheimer's Disease in a Clinical Setting. J Alzheimers Dis. 2017; 59(2):603-614. Iaccarino L, Chiotis K, Alongi P, Almkvist O, Wall A, Cerami C, Bettinardi V, Gianolli L, Nordberg A, Perani D. PMID: 28671117.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    30. Regional tau deposition measured by [18F]THK5317 positron emission tomography is associated to cognition via glucose metabolism in Alzheimer's disease. Alzheimers Res Ther. 2016 Sep 29; 8(1):38. Saint-Aubert L, Almkvist O, Chiotis K, Almeida R, Wall A, Nordberg A. PMID: 27683159; PMCID: PMC5041516.
      View in: PubMed   Mentions: 30     Fields:    
    31. Comparability of [18F]THK5317 and [11C]PIB blood flow proxy images with [18F]FDG positron emission tomography in Alzheimer's disease. J Cereb Blood Flow Metab. 2017 Feb; 37(2):740-749. Rodriguez-Vieitez E, Leuzy A, Chiotis K, Saint-Aubert L, Wall A, Nordberg A. PMID: 27107028; PMCID: PMC5381463.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    32. Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study. Brain. 2016 09; 139(Pt 9):2540-53. Leuzy A, Chiotis K, Hasselbalch SG, Rinne JO, de Mendonça A, Otto M, Lleó A, Castelo-Branco M, Santana I, Johansson J, Anderl-Straub S, von Arnim CA, Beer A, Blesa R, Fortea J, Herukka SK, Portelius E, Pannee J, Zetterberg H, Blennow K, Nordberg A. PMID: 27401520; PMCID: PMC4995359.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    33. Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm. Eur J Nucl Med Mol Imaging. 2016 Aug; 43(9):1686-99. Chiotis K, Saint-Aubert L, Savitcheva I, Jelic V, Andersen P, Jonasson M, Eriksson J, Lubberink M, Almkvist O, Wall A, Antoni G, Nordberg A. PMID: 26996778; PMCID: PMC4932128.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    34. Comparison of Early-Phase 11C-Deuterium-l-Deprenyl and 11C-Pittsburgh Compound B PET for Assessing Brain Perfusion in Alzheimer Disease. J Nucl Med. 2016 07; 57(7):1071-7. Rodriguez-Vieitez E, Carter SF, Chiotis K, Saint-Aubert L, Leuzy A, Schöll M, Almkvist O, Wall A, Långström B, Nordberg A. PMID: 26912447.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    35. Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease. Brain. 2016 Mar; 139(Pt 3):922-36. Rodriguez-Vieitez E, Saint-Aubert L, Carter SF, Almkvist O, Farid K, Schöll M, Chiotis K, Thordardottir S, Graff C, Wall A, Långström B, Nordberg A. PMID: 26813969; PMCID: PMC4766380.
      View in: PubMed   Mentions: 130     Fields:    Translation:Humans
    36. Tracer Kinetic Analysis of (S)-¹⁸F-THK5117 as a PET Tracer for Assessing Tau Pathology. J Nucl Med. 2016 Apr; 57(4):574-81. Jonasson M, Wall A, Chiotis K, Saint-Aubert L, Wilking H, Sprycha M, Borg B, Thibblin A, Eriksson J, Sörensen J, Antoni G, Nordberg A, Lubberink M. PMID: 26795290.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    37. Amyloid PET in European and North American cohorts; and exploring age as a limit to clinical use of amyloid imaging. Eur J Nucl Med Mol Imaging. 2015 Sep; 42(10):1492-506. Chiotis K, Carter SF, Farid K, Savitcheva I, Nordberg A, Diagnostic Molecular Imaging (DiMI) network and the Alzheimer’s Disease Neuroimaging Initiative. PMID: 26130168; PMCID: PMC4521094.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    38. Concordance and Diagnostic Accuracy of [11C]PIB PET and Cerebrospinal Fluid Biomarkers in a Sample of Patients with Mild Cognitive Impairment and Alzheimer's Disease. J Alzheimers Dis. 2015; 45(4):1077-88. Leuzy A, Carter SF, Chiotis K, Almkvist O, Wall A, Nordberg A. PMID: 25649653.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    39. Role of anthropometric characteristics in idiopathic carpal tunnel syndrome. Arch Phys Med Rehabil. 2013 Apr; 94(4):737-44. Chiotis K, Dimisianos N, Rigopoulou A, Chrysanthopoulou A, Chroni E. PMID: 23178273.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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