Laya Ekhlaspour, MD

Title(s)Assistant Professor, Pediatrics
SchoolSchool of Medicine
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    1. Outcomes in Pump- and CGM-Baseline Use Subgroups in the International Diabetes Closed-Loop (iDCL) Trial. J Diabetes Sci Technol. 2022 Apr 26; 19322968221089361. Ekhlaspour L, Raghinaru D, Forlenza GP, Isganaitis E, Kudva YC, Lam DW, Levister C, O'Malley G, Church MM, Lum JW, Buckingham B, Brown SA. PMID: 35473359.
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    2. Glycemic Outcomes in Baseline Hemoglobin A1C Subgroups in the International Diabetes Closed-Loop Trial. Diabetes Technol Ther. 2022 Feb 08. Ekhlaspour L, Town M, Raghinaru D, Lum JW, Brown SA, Buckingham BA. PMID: 35020488.
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    3. Glycemic outcomes of children 2-6 years of age with type 1 diabetes during the pediatric MiniMed™ 670G system trial. Pediatr Diabetes. 2022 Jan 10. Forlenza GP, Ekhlaspour L, DiMeglio LA, Fox LA, Rodriguez H, Shulman DI, Kaiserman KB, Liljenquist DR, Shin J, Lee SW, Buckingham BA. PMID: 35001477.
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    4. Impact of a Novel Diabetes Support System on a Cohort of Individuals With Type 1 Diabetes Treated With Multiple Daily Injections: A Multicenter Randomized Study. Diabetes Care. 2022 01 01; 45(1):186-193. Bisio A, Anderson S, Norlander L, O'Malley G, Robic J, Ogyaadu S, Hsu L, Levister C, Ekhlaspour L, Lam DW, Levy C, Buckingham B, Breton MD. PMID: 34794973; PMCID: PMC8753765.
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    5. Patient-Reported Outcomes in a Randomized Trial of Closed-Loop Control: The Pivotal International Diabetes Closed-Loop Trial. Diabetes Technol Ther. 2021 10; 23(10):673-683. Kudva YC, Laffel LM, Brown SA, Raghinaru D, Pinsker JE, Ekhlaspour L, Levy CJ, Messer LH, Kovatchev BP, Lum JW, Beck RW, Gonder-Frederick L, iDCL Trial Research Group. PMID: 34115959; PMCID: PMC8573794.
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    6. Adjunctive Therapies to Optimize Closed-loop Glucose Control. J Diabetes Sci Technol. 2021 11; 15(6):1243-1251. Srinivasan S, Ekhlaspour L, Cengiz E. PMID: 34315267; PMCID: PMC8655279.
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    7. Diabetes Technology and Therapy in the Pediatric Age Group. Diabetes Technol Ther. 2021 06; 23(S2):S113-S130. Maahs DM, Ekhlaspour L, Shalitin S. PMID: 34061625; PMCID: PMC8881949.
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    8. Clinical Management and Pump Parameter Adjustment of the Control-IQ Closed-Loop Control System: Results from a 6-Month, Multicenter, Randomized Clinical Trial. Diabetes Technol Ther. 2021 04; 23(4):245-252. O'Malley G, Messer LH, Levy CJ, Pinsker JE, Forlenza GP, Isganaitis E, Kudva YC, Ekhlaspour L, Raghinaru D, Lum J, Brown SA, iDCL Trial Research Group. PMID: 33155824; PMCID: PMC8114941.
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    9. Predictors of Time-in-Range (70-180 mg/dL) Achieved Using a Closed-Loop Control System. Diabetes Technol Ther. 2021 07; 23(7):475-481. Schoelwer MJ, Kanapka LG, Wadwa RP, Breton MD, Ruedy KJ, Ekhlaspour L, Forlenza GP, Cobry EC, Messer LH, Cengiz E, Jost E, Carria L, Emory E, Hsu LJ, Weinzimer SA, Buckingham BA, Lal RA, Oliveri MC, Kollman CC, Dokken BB, Cherñavvsky DR, Beck RW, DeBoer MD, iDCL Trial Research Group. PMID: 33689454; PMCID: PMC8252894.
      View in: PubMed   Mentions: 1     Fields:    
    10. Health-Related Quality of Life and Treatment Satisfaction in Parents and Children with Type 1 Diabetes Using Closed-Loop Control. Diabetes Technol Ther. 2021 06; 23(6):401-409. Cobry EC, Kanapka LG, Cengiz E, Carria L, Ekhlaspour L, Buckingham BA, Hood KK, Hsu LJ, Messer LH, Schoelwer MJ, Emory E, Ruedy KJ, Beck RW, Wadwa RP, Gonder-Frederick L, iDCL Trial Research Group. PMID: 33404325; PMCID: PMC8215424.
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    11. Closed-Loop Insulin Therapy Improves Glycemic Control in Adolescents and Young Adults: Outcomes from the International Diabetes Closed-Loop Trial. Diabetes Technol Ther. 2021 05; 23(5):342-349. Isganaitis E, Raghinaru D, Ambler-Osborn L, Pinsker JE, Buckingham BA, Wadwa RP, Ekhlaspour L, Kudva YC, Levy CJ, Forlenza GP, Beck RW, Kollman C, Lum JW, Brown SA, Laffel LM, iDCL Trial Research Group. PMID: 33216667; PMCID: PMC8080922.
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    12. First Outpatient Evaluation of a Tubeless Automated Insulin Delivery System with Customizable Glucose Targets in Children and Adults with Type 1 Diabetes. Diabetes Technol Ther. 2021 06; 23(6):410-424. Forlenza GP, Buckingham BA, Brown SA, Bode BW, Levy CJ, Criego AB, Wadwa RP, Cobry EC, Slover RJ, Messer LH, Berget C, McCoy S, Ekhlaspour L, Kingman RS, Voelmle MK, Boyd J, O'Malley G, Grieme A, Kivilaid K, Kleve K, Dumais B, Vienneau T, Huyett LM, Lee JB, O'Connor J, Benjamin E, Ly TT. PMID: 33325779; PMCID: PMC8215410.
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    13. Fast-Acting Insulin Aspart Use with the MiniMedTM 670G System. Diabetes Technol Ther. 2021 01; 23(1):1-7. Hsu L, Buckingham B, Basina M, Ekhlaspour L, von Eyben R, Wang J, Lal RA. PMID: 32520594; PMCID: PMC7864093.
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    14. Extended Use of the Control-IQ Closed-Loop Control System in Children With Type 1 Diabetes. Diabetes Care. 2021 02; 44(2):473-478. Kanapka LG, Wadwa RP, Breton MD, Ruedy KJ, Ekhlaspour L, Forlenza GP, Cengiz E, Schoelwer MJ, Jost E, Carria L, Emory E, Hsu LJ, Weinzimer SA, DeBoer MD, Buckingham BA, Oliveri M, Kollman C, Dokken BB, Cherñavvsky D, Beck RW, iDCL Trial Research Group. PMID: 33355258; PMCID: PMC7818334.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Safety and Performance of the Tandem t:slim X2 with Control-IQ Automated Insulin Delivery System in Toddlers and Preschoolers. Diabetes Technol Ther. 2021 05; 23(5):384-391. Ekhlaspour L, Schoelwer MJ, Forlenza GP, DeBoer MD, Norlander L, Hsu L, Kingman R, Boranian E, Berget C, Emory E, Buckingham BA, Breton MD, Wadwa RP. PMID: 33226837; PMCID: PMC8080923.
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    16. A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes. N Engl J Med. 2020 08 27; 383(9):836-845. Breton MD, Kanapka LG, Beck RW, Ekhlaspour L, Forlenza GP, Cengiz E, Schoelwer M, Ruedy KJ, Jost E, Carria L, Emory E, Hsu LJ, Oliveri M, Kollman CC, Dokken BB, Weinzimer SA, DeBoer MD, Buckingham BA, Cherñavvsky D, Wadwa RP, iDCL Trial Research Group. PMID: 32846062; PMCID: PMC7920146.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    17. Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial. Diabetes Care. 2020 08; 43(8):1822-1828. Brown SA, Beck RW, Raghinaru D, Buckingham BA, Laffel LM, Wadwa RP, Kudva YC, Levy CJ, Pinsker JE, Dassau E, Doyle FJ, Ambler-Osborn L, Anderson SM, Church MM, Ekhlaspour L, Forlenza GP, Levister C, Simha V, Breton MD, Kollman C, Lum JW, Kovatchev BP, iDCL Trial Research Group. PMID: 32471910; PMCID: PMC7372060.
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    18. Erratum. Randomized Controlled Trial of Mobile Closed-Loop Control. Diabetes Care 2020;43:607-615. Diabetes Care. 2020 Jun; 43(6):1366. Kovatchev B, Anderson SM, Raghinaru D, Kudva YC, Laffel LM, Levy C, Pinsker JE, Wadwa RP, Buckingham B, Doyle FJ, Brown SA, Church MM, Dadlani V, Dassau E, Ekhlaspour L, Forlenza GP, Isganaitis E, Lam DW, Lum J, Beck RW, iDCL Study Group. PMID: 32245747; PMCID: PMC7245358.
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    19. Randomized Controlled Trial of Mobile Closed-Loop Control. Diabetes Care. 2020 03; 43(3):607-615. Kovatchev B, Anderson SM, Raghinaru D, Kudva YC, Laffel LM, Levy C, Pinsker JE, Wadwa RP, Buckingham B, Doyle FJ, Brown SA, Church MM, Dadlani V, Dassau E, Ekhlaspour L, Forlenza GP, Isganaitis E, Lam DW, Lum J, Beck RW, iDCL Study Group. PMID: 31937608; PMCID: PMC7035585.
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    20. Realizing a Closed-Loop (Artificial Pancreas) System for the Treatment of Type 1 Diabetes. Endocr Rev. 2019 12 01; 40(6):1521-1546. Lal RA, Ekhlaspour L, Hood K, Buckingham B. PMID: 31276160; PMCID: PMC6821212.
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    21. Safety and Performance of the Omnipod Hybrid Closed-Loop System in Adults, Adolescents, and Children with Type 1 Diabetes Over 5 Days Under Free-Living Conditions. Diabetes Technol Ther. 2020 03; 22(3):174-184. Sherr JL, Buckingham BA, Forlenza GP, Galderisi A, Ekhlaspour L, Wadwa RP, Carria L, Hsu L, Berget C, Peyser TA, Lee JB, O'Connor J, Dumais B, Huyett LM, Layne JE, Ly TT. PMID: 31596130; PMCID: PMC7047109.
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    22. Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes. N Engl J Med. 2019 10 31; 381(18):1707-1717. Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, Laffel LM, Levy CJ, Pinsker JE, Wadwa RP, Dassau E, Doyle FJ, Anderson SM, Church MM, Dadlani V, Ekhlaspour L, Forlenza GP, Isganaitis E, Lam DW, Kollman C, Beck RW, iDCL Trial Research Group. PMID: 31618560; PMCID: PMC7076915.
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    23. Feasibility Studies of an Insulin-Only Bionic Pancreas in a Home-Use Setting. J Diabetes Sci Technol. 2019 11; 13(6):1001-1007. Ekhlaspour L, Nally LM, El-Khatib FH, Ly TT, Clinton P, Frank E, Tanenbaum ML, Hanes SJ, Selagamsetty RR, Hood K, Damiano ER, Buckingham BA. PMID: 31470740; PMCID: PMC6835195.
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    24. Task-related fMRI BOLD response to hyperinsulinemia in healthy older adults. JCI Insight. 2019 06 18; 5. Williams VJ, Trombetta BA, Jafri RZ, Koenig AM, Wennick CD, Carlyle BC, Ekhlaspour L, Ahima RS, Russell SJ, Salat DH, Arnold SE. PMID: 31211691; PMCID: PMC6675560.
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    25. A Review of Continuous Glucose Monitoring Data Interpretation in the Age of Automated Insulin Delivery. J Diabetes Sci Technol. 2019 07; 13(4):645-663. Ekhlaspour L, Tabatabai I, Buckingham B. PMID: 31130007; PMCID: PMC6610610.
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    26. Closed loop control in adolescents and children during winter sports: Use of the Tandem Control-IQ AP system. Pediatr Diabetes. 2019 09; 20(6):759-768. Ekhlaspour L, Forlenza GP, Chernavvsky D, Maahs DM, Wadwa RP, Deboer MD, Messer LH, Town M, Pinnata J, Kruse G, Kovatchev BP, Buckingham BA, Breton MD. PMID: 31099946; PMCID: PMC6679803.
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    27. Successful At-Home Use of the Tandem Control-IQ Artificial Pancreas System in Young Children During a Randomized Controlled Trial. Diabetes Technol Ther. 2019 04; 21(4):159-169. Forlenza GP, Ekhlaspour L, Breton M, Maahs DM, Wadwa RP, DeBoer M, Messer LH, Town M, Pinnata J, Kruse G, Buckingham BA, Cherñavvsky D. PMID: 30888835; PMCID: PMC6909715.
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    28. Predictive Low-Glucose Suspend Reduces Hypoglycemia in Adults, Adolescents, and Children With Type 1 Diabetes in an At-Home Randomized Crossover Study: Results of the PROLOG Trial. Diabetes Care. 2018 10; 41(10):2155-2161. Forlenza GP, Li Z, Buckingham BA, Pinsker JE, Cengiz E, Wadwa RP, Ekhlaspour L, Church MM, Weinzimer SA, Jost E, Marcal T, Andre C, Carria L, Swanson V, Lum JW, Kollman C, Woodall W, Beck RW. PMID: 30089663.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    29. Predictive hyperglycemia and hypoglycemia minimization: In-home double-blind randomized controlled evaluation in children and young adolescents. Pediatr Diabetes. 2018 05; 19(3):420-428. Forlenza GP, Raghinaru D, Cameron F, Wayne Bequette B, Peter Chase H, Paul Wadwa R, Maahs DM, Jost E, Ly TT, Wilson DM, Norlander L, Ekhlaspour L, Min H, Clinton P, Njeru N, Lum JW, Kollman C, Beck RW, Buckingham BA, In-Home Closed-Loop (IHCL) Study Group. PMID: 29159870; PMCID: PMC5951790.
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    30. In-Home Closed Loop Control for Artificial Pancreas: Patient and Provider Perspective. Diabetes Technol Ther. 2017 01; 19(1):4-6. Ekhlaspour L, Maahs DM. PMID: 28055224; PMCID: PMC6435341.
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    31. Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial. Lancet. 2017 01 28; 389(10067):369-380. El-Khatib FH, Balliro C, Hillard MA, Magyar KL, Ekhlaspour L, Sinha M, Mondesir D, Esmaeili A, Hartigan C, Thompson MJ, Malkani S, Lock JP, Harlan DM, Clinton P, Frank E, Wilson DM, DeSalvo D, Norlander L, Ly T, Buckingham BA, Diner J, Dezube M, Young LA, Goley A, Kirkman MS, Buse JB, Zheng H, Selagamsetty RR, Damiano ER, Russell SJ. PMID: 28007348; PMCID: PMC5358809.
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    32. Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders. J Autism Dev Disord. 2016 Nov; 46(11):3387-3391. Ekhlaspour L, Baskaran C, Campoverde KJ, Sokoloff NC, Neumeyer AM, Misra M. PMID: 27491424; PMCID: PMC5074906.
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    33. Comparative Accuracy of 17 Point-of-Care Glucose Meters. J Diabetes Sci Technol. 2017 05; 11(3):558-566. Ekhlaspour L, Mondesir D, Lautsch N, Balliro C, Hillard M, Magyar K, Radocchia LG, Esmaeili A, Sinha M, Russell SJ. PMID: 27697848; PMCID: PMC5505415.
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    34. Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a randomised crossover trial. Lancet Diabetes Endocrinol. 2016 Mar; 4(3):233-243. Russell SJ, Hillard MA, Balliro C, Magyar KL, Selagamsetty R, Sinha M, Grennan K, Mondesir D, Ekhlaspour L, Zheng H, Damiano ER, El-Khatib FH. PMID: 26850709; PMCID: PMC4799495.
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