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The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes. Diabetologia. 2023 May 06.
Huerta-Chagoya A, Schroeder P, Mandla R, Deutsch AJ, Zhu W, Petty L, Yi X, Cole JB, Udler MS, Dornbos P, Porneala B, DiCorpo D, Liu CT, Li JH, Szczerbinski L, Kaur V, Kim J, Lu Y, Martin A, Eizirik DL, Marchetti P, Marselli L, Chen L, Srinivasan S, Todd J, Flannick J, Gubitosi-Klug R, Levitsky L, Shah R, Kelsey M, Burke B, Dabelea DM, Divers J, Marcovina S, Stalbow L, Loos RJF, Darst BF, Kooperberg C, Raffield LM, Haiman C, Sun Q, McCormick JB, Fisher-Hoch SP, Ordoñez ML, Meigs J, Baier LJ, González-Villalpando C, González-Villalpando ME, Orozco L, García-García L, Moreno-Estrada A, Mexican Biobank, Aguilar-Salinas CA, Tusié T, Dupuis J, Ng MCY, Manning A, Highland HM, Cnop M, Hanson R, Below J, Florez JC, Leong A, Mercader JM. PMID: 37148359.
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Identification of Genetic Variation Influencing Metformin Response in a Multi-Ancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP). Diabetes. 2022 Dec 16.
Li JH, Perry JA, Jablonski KA, Srinivasan S, Chen L, Todd JN, Harden M, Mercader JM, Pan Q, Dawed AY, Yee SW, Pearson ER, Giacomini KM, Giri A, Hung AM, Xiao S, Williams LK, Franks PW, Hanson RL, Kahn SE, Knowler WC, Pollin TI, Florez JC, Diabetes Prevention Program Research Group. PMID: 36525397.
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1 Fields:
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Real-Time Continuous Glucose Monitoring in Adolescents and Young Adults With Type 2 Diabetes Can Improve Quality of Life. J Diabetes Sci Technol. 2022 Nov 23; 19322968221139873.
Chesser H, Srinivasan S, Puckett C, Gitelman SE, Wong JC. PMID: 36416098.
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1 Fields:
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The Coronavirus Disease 2019 Pandemic is Associated with a Substantial Rise in Frequency and Severity of Presentation of Youth-Onset Type 2 Diabetes. J Pediatr. 2022 12; 251:51-59.e2.
Magge SN, Wolf RM, Pyle L, Brown EA, Benavides VC, Bianco ME, Chao LC, Cymbaluk A, Balikcioglu PG, Halpin K, Hsia DS, Huerta-Saenz L, Kim JJ, Kumar S, Levitt Katz LE, Marks BE, Neyman A, O'Sullivan KL, Pillai SS, Shah AS, Shoemaker AH, Siddiqui JAW, Srinivasan S, Thomas IH, Tryggestad JB, Yousif MF, Kelsey MM, COVID-19 and Type 2 Diabetes Consortium. PMID: 35985535; PMCID: PMC9383958.
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4 Fields:
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HumansPHPublic Health
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Rickets in a child with prolonged acquired hypothyroidism secondary to Hashimoto's thyroiditis. Endocrinol Diabetes Metab Case Rep. 2022 Aug 01; 2022.
Schulmeister C, Lee J, Perwad F, Long R, Srinivasan S. PMID: 35979838; PMCID: PMC9422259.
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The Genetics of Type 2 Diabetes in Youth: Where We Are and the Road Ahead. J Pediatr. 2022 08; 247:17-21.
Srinivasan S, Todd J. PMID: 35660490; PMCID: PMC9833991.
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Humans
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Genome-wide Association Study of Lipid Traits in Youth With Type 2 Diabetes. J Endocr Soc. 2021 Nov 01; 5(11):bvab139.
Santoro N, Chen L, Todd J, Divers J, Shah AS, Gidding SS, Burke B, Haymond M, Lange L, Marcovina S, Flannick J, Caprio S, Florez JC, Srinivasan S. PMID: 34568709; PMCID: PMC8459445.
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Monogenic Diabetes in Youth With Presumed Type 2 Diabetes: Results From the Progress in Diabetes Genetics in Youth (ProDiGY) Collaboration. Diabetes Care. 2021 Aug 06.
Todd JN, Kleinberger JW, Zhang H, Srinivasan S, Tollefsen SE, Levitsky LL, Levitt Katz LE, Tryggestad JB, Bacha F, Imperatore G, Lawrence JM, Pihoker C, Divers J, Flannick J, Dabelea D, Florez JC, Pollin TI. PMID: 34362814; PMCID: PMC8929184.
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6 Fields:
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Adjunctive Therapies to Optimize Closed-loop Glucose Control. J Diabetes Sci Technol. 2021 11; 15(6):1243-1251.
Srinivasan S, Ekhlaspour L, Cengiz E. PMID: 34315267; PMCID: PMC8655279.
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3 Fields:
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Humans
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23-OR: ADA Presidents’ Select Abstract: Genetic Architecture and Novel Genes Implicated in Youth-Onset Type 2 Diabetes. Diabetes. 2021 Jun 21; 70(Supplement 1):23-or.
KWAK KS, SRINIVASAN SS, CHEN CL, TODD TJ, JENSEN JE, DIVERS DJ, MOTTL MA, PIHOKER PC, GANDICA GR, LAFFEL LL, ISGANAITIS IE, HAYMOND HM, LEVITSKY LL, POLLIN PT, FLOREZ FJ, FLANNICK FJ. .
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249-OR: Type 2 Diabetes (T2D) Genetic Clusters for Association with Glycemic Responses to Intervention for Diabetes Prevention. Diabetes. 2021 Jun 21; 70(Supplement 1):249-or.
BILLINGS BL, JABLONSKI JK, FRANKS FP, GOLDBERG GR, HIVERT HM, KAHN KS, KNOWLER KW, LEE LC, MERINO MJ, RAGHAVAN RS, SRINIVASAN SS, XU XJ, FLOREZ FJ, UDLER UM. .
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28-OR: Identification of Ancestry-Specific Alleles in a Genome-Wide Association Study (GWAS) for Metformin (MET) Response in the Diabetes Prevention Program (DPP). Diabetes. 2021 Jun 21; 70(Supplement 1):28-or.
LI LJ, PERRY PJ, JABLONSKI JK, CHEN CL, SRINIVASAN SS, TODD TJ, HARDEN HM, MERCADER MJ, FRANKS FP, HANSON HR, KAHN KS, KNOWLER KW, POLLIN PT, FLOREZ FJ, GROUP GD. .
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900-P: Continuous Glucose Monitoring in Youth with Type 2 Diabetes: A Pilot and Feasibility Study. Diabetes. 2021 Jun 21; 70(Supplement 1):900-p.
CHESSER CH, SRINIVASAN SS, WONG WJ. .
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The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes. 2021 04; 70(4):996-1005.
Srinivasan S, Chen L, Todd J, Divers J, Gidding S, Chernausek S, Gubitosi-Klug RA, Kelsey MM, Shah R, Black MH, Wagenknecht LE, Manning A, Flannick J, Imperatore G, Mercader JM, Dabelea D, Florez JC, ProDiGY Consortium. PMID: 33479058; PMCID: PMC7980197.
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12 Fields:
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Humans
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Overview and Initial Management of Type 2 Diabetes in Youth. . 2020 Sep 26; 313-321.
Chesser CH, Srinivasan SS. .
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A Polygenic Lipodystrophy Genetic Risk Score Characterizes Risk Independent of BMI in the Diabetes Prevention Program. J Endocr Soc. 2019 Sep 01; 3(9):1663-1677.
Srinivasan S, Jablonski KA, Knowler WC, Dagogo-Jack S, E Kahn S, Boyko EJ, Bray GA, Horton ES, Hivert MF, Goldberg R, Chen L, Mercader J, Harden M, Florez JC, Diabetes Prevention Program Research Group. PMID: 31428720; PMCID: PMC6694040.
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7
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177-OR: Genome-Wide Association Study of Lipid Traits in Youth with Type 2 Diabetes: The ProDiGY (Progress in Diabetes Genetics in Youth) Consortium. Diabetes. 2019 Jun 1; 68(Supplement 1):177-or.
CHEN CL, SRINIVASAN SS, SANTORO SN, TODD TJ, DIVERS DJ, SHAH SA, GIDDING GS, BURKE BB, HAYMOND HM, LANGE LL, MARCOVINA MS, CHAIT CA, FLANNICK FJ, CAPRIO CS, FLOREZ FJ. .
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MON-268 A Rare Case of Primary Hypoaldosteronism in a Newborn. Journal of the Endocrine Society. 2019 Apr 15; 3(Suppl 1).
Mody MA, Lee LJ, Tenney TJ, Srinivasan SS. .
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A Comprehensive Type 1 Diabetes Genetic Risk Score Is Associated with Type 2 Diabetes in the Framingham Heart Study. Diabetes. 2018 Jun 22; 67(Supplement 1):1715-p.
SRINIVASAN SS, LEONG LA, UDLER UM, PORNEALA PB, MEIGS MJ, RICH RS, DUPUIS DJ. .
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Advances in the Genetics of Youth-Onset Type 2 Diabetes. Curr Diab Rep. 2018 06 22; 18(8):57.
Todd JN, Srinivasan S, Pollin TI. PMID: 29931398; PMCID: PMC6051541.
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13 Fields:
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Humans
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Pharmacogenetics of Antidiabetic Drugs. Adv Pharmacol. 2018; 83:361-389.
Srinivasan S, Yee SW, Giacomini KM. PMID: 29801583.
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4 Fields:
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Humans
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The First Genome-Wide Association Study (GWAS) for Type 2 Diabetes in Youth from the Progress in Diabetes Genetics in Youth (ProDiGY) Collaboration. Diabetes. 2018 May 1; 67(Supplement 1):1703-p.
SRINIVASAN SS, TODD TJ, CHEN CL, DIVERS DJ, GIDDING GS, CHERNAUSEK CS, GUBITOSI-KLUG GR, KELSEY KM, SHAH SR, BLACK BM, WAGENKNECHT WL, MERCADER MJ, MANNING MA, FLANNICK FJ, DABELEA DD, FLOREZ FJ. .
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Monogenic Diabetes in the Progress for Diabetes Genetics in Youth (ProDiGY) Collaboration. Diabetes. 2018 May 1; 67(Supplement 1):268-or.
TODD TJ, KLEINBERGER KJ, SRINIVASAN SS, TOLLEFSEN TS, LEVITSKY LL, KATZ KL, TRYGGESTAD TJ, BACHA BF, IMPERATORE IG, LAWRENCE LJ, PIHOKER PC, DIVERS DJ, FLANNICK FJ, DABELEA DD, FLOREZ FJ, POLLIN PT. .
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TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH). Diabetes Care. 2018 03; 41(3):554-561.
Srinivasan S, Kaur V, Chamarthi B, Littleton KR, Chen L, Manning AK, Merino J, Thomas MK, Hudson M, Goldfine A, Florez JC. PMID: 29326107; PMCID: PMC5829963.
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20 Fields:
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Humans
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Radovick and Misra’s Pediatric Endocrinology: A Practical Clinical Guide, Springer International. Type 2 diabetes in youth. 2018; 737-754.
Srinivasan S., Levitsky L.
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In Advances in Pharmacology, Elsevier. The Pharmacogenetics of Anti-Diabetic Drugs. 2018; 361-381.
Srinivasan S., Yee SW., Giacomini K
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Type 2 Diabetes Mellitus in Youth. Pediatric Endocrinology. 2018 Jan 1; 737-753.
Srinivasan SS, Levitsky LL. .
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Calcium and Vitamin D Supplement Prescribing Practices among Providers Caring for Children with Autism Spectrum Disorders: Are We Addressing Bone Health? Autism Res Treat. 2016; 2016:6763205.
Srinivasan S, O'Rourke J, Bersche Golas S, Neumeyer A, Misra M. PMID: 27042348; PMCID: PMC4799806.
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5
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Therapeutic Challenges in Diabetes Prevention: We Have Not Found the "Exercise Pill". Clin Pharmacol Ther. 2015 Aug; 98(2):162-9.
Srinivasan S, Florez JC. PMID: 25974616; PMCID: PMC4511706.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsPHPublic Health
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Hyperthyroidism in children. Pediatr Rev. 2015 Jun; 36(6):239-48.
Srinivasan S, Misra M. PMID: 26034254.
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13 Fields:
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Humans
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Hyperthyroidism in Children. Pediatrics in Review. 2015 Jun 1; 36(6):239-248.
Srinivasan SS, Misra MM. .
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Comparison of bone age readings by pediatric endocrinologists and pediatric radiologists using two bone age atlases. Pediatr Radiol. 2011 Jun; 41(6):690-3.
Kaplowitz P, Srinivasan S, He J, McCarter R, Hayeri MR, Sze R. PMID: 21161206.
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PubMed Mentions:
10 Fields:
Translation:
Humans