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TAS0612, a Novel RSK, AKT, and S6K Inhibitor, Exhibits Antitumor Effects in Preclinical Tumor Models. Mol Cancer Ther. 2024 Feb 01; 23(2):174-186.
Ichikawa K, Ito S, Kato E, Abe N, Machida T, Iwasaki J, Tanaka G, Araki H, Wakayama K, Jona H, Sugimoto T, Miyadera K, Ohkubo S. PMID: 37906695.
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1 Fields:
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HumansCells
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Maternal Mental Health Diagnoses and Infant Emergency Department Use, Hospitalizations, and Death. Acad Pediatr. 2023 Dec 14.
Abe N, Baer RJ, Jelliffe-Pawlowski L, Chambers CD, Bandoli G. PMID: 38103588.
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[Posterior reversible encephalopathy syndrome during nilotinib treatment for chronic myeloid leukemia]. Rinsho Ketsueki. 2023; 64(12):1514-1518.
Kudo D, Suzuki H, Abe N, Hirai R, Tanimura A, Takeshita M, Miwa A. PMID: 38220151.
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Humans
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Predictive Factors for Delayed Surgical Intervention in Children With Epidural Hematomas. Pediatr Emerg Care. 2023 Jun 01; 39(6):402-407.
Abe N, Gardiner M, Dory C, Gonda D, Harvey H, Hilfiker M, Hollenbach K, Kanegaye JT. PMID: 36730955.
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Humans
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TAS6417/CLN-081 Is a Pan-Mutation-Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations. Mol Cancer Res. 2019 11; 17(11):2233-2243.
Udagawa H, Hasako S, Ohashi A, Fujioka R, Hakozaki Y, Shibuya M, Abe N, Komori T, Haruma T, Terasaka M, Fujita R, Hashimoto A, Funabashi K, Yasuda H, Miyadera K, Goto K, Costa DB, Kobayashi SS. PMID: 31467113; PMCID: PMC6872223.
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25 Fields:
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HumansCells
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Dietary iron restriction leads to a reduction in hepatic fibrosis in a rat model of non-alcoholic steatohepatitis. Biol Open. 2019 May 16; 8(5).
Abe N, Tsuchida T, Yasuda SI, Oka K. PMID: 31097447; PMCID: PMC6550076.
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9 Fields:
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Longitudinal characterization of diet-induced genetic murine models of non-alcoholic steatohepatitis with metabolic, histological, and transcriptomic hallmarks of human patients. Biol Open. 2019 May 01; 8(5).
Abe N, Kato S, Tsuchida T, Sugimoto K, Saito R, Verschuren L, Kleemann R, Oka K. PMID: 31023717; PMCID: PMC6550083.
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15 Fields:
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TAS6417, A Novel EGFR Inhibitor Targeting Exon 20 Insertion Mutations. Mol Cancer Ther. 2018 08; 17(8):1648-1658.
Hasako S, Terasaka M, Abe N, Uno T, Ohsawa H, Hashimoto A, Fujita R, Tanaka K, Okayama T, Wadhwa R, Miyadera K, Aoyagi Y, Yonekura K, Matsuo K. PMID: 29748209.
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PubMed Mentions:
37 Fields:
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HumansAnimals
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The p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas. Cell Death Discov. 2018; 4:56.
Miyazaki M, Otomo R, Matsushima-Hibiya Y, Suzuki H, Nakajima A, Abe N, Tomiyama A, Ichimura K, Matsuda K, Watanabe T, Ochiya T, Nakagama H, Sakai R, Enari M. PMID: 29760954; PMCID: PMC5945735.
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13
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3,4-Dihydroxyphenylacetic acid is a predominant biologically-active catabolite of quercetin glycosides. Food Res Int. 2016 Nov; 89(Pt 1):716-723.
Tang Y, Nakashima S, Saiki S, Myoi Y, Abe N, Kuwazuru S, Zhu B, Ashida H, Murata Y, Nakamura Y. PMID: 28460970.
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13 Fields:
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Benzyl isothiocyanate inhibits IL-13 expression in human basophilic KU812 cells. Biosci Biotechnol Biochem. 2015; 79(1):159-63.
Tang Y, Abe N, Yoshimoto M, Zhu B, Murata Y, Nakamura Y. PMID: 25253661.
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2 Fields:
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HumansCells
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Thiol modification by bioactivated polyphenols and its potential role in skin inflammation. Biosci Biotechnol Biochem. 2014; 78(6):1067-70.
Nakamura Y, Ishii T, Abe N, Murata Y. PMID: 25036136.
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1 Fields:
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Animals
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Treatment of mid-pregnant mice with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces abnormal retinal vascular patterning in their newborn pups. Birth Defects Res B Dev Reprod Toxicol. 2014 Aug; 101(4):293-9.
Morita A, Nakahara T, Abe N, Kurauchi Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K. PMID: 24831925.
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PubMed Mentions:
2 Fields:
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Animals
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(-)-Epigallocatechin-3-gallate ameliorates photodynamic therapy responses in an in vitro T lymphocyte model. Phytother Res. 2014 Oct; 28(10):1486-91.
Qi H, Abe N, Zhu B, Murata Y, Nakamura Y. PMID: 24700514.
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4 Fields:
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HumansCells
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Trehalose solution protects mesothelium and reduces bowel adhesions. J Surg Res. 2014 Sep; 191(1):224-30.
Ohata A, Tamura N, Iwata K, Abe N, Doi K, Saito Y, Katoh M, Nojima H. PMID: 24768023.
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PubMed Mentions:
2 Fields:
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HumansAnimalsCells
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Ascorbic acid synergistically potentiates phloxine b-induced photocytotoxicity in human acute promyelocytic leukemia cells. J Biochem Mol Toxicol. 2014 Apr; 28(4):167-73.
Qi H, Wu Q, Abe N, Saiki S, Zhu B, Murata Y, Nakamura Y. PMID: 24488945.
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1 Fields:
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HumansCells
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Effects of pre- and post-natal treatment with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, on retinal vascular development and patterning in mice. Exp Eye Res. 2014 Mar; 120:127-37.
Morita A, Nakahara T, Abe N, Kurauchi Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K. PMID: 24462631.
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Animals
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KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces intrauterine growth restriction in mice. Birth Defects Res B Dev Reprod Toxicol. 2013 Aug; 98(4):297-303.
Abe N, Nakahara T, Morita A, Wada Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K. PMID: 23780833.
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1 Fields:
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Animals
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Role of vascular endothelial growth factor in maintenance of pregnancy in mice. Endocrinology. 2013 Feb; 154(2):900-10.
Wada Y, Ozaki H, Abe N, Mori A, Sakamoto K, Nagamitsu T, Nakahara T, Ishii K. PMID: 23307787.
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7 Fields:
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Animals
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Evaluation of Waist Circumference Cut-off Values as a Marker for Fatty Liver among Japanese Workers. Saf Health Work. 2012 Dec; 3(4):287-93.
Abe N, Honda S, Jahng D. PMID: 23251844; PMCID: PMC3521927.
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4
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Perioperative oral administration of cystine and theanine enhances recovery after distal gastrectomy: a prospective randomized trial. JPEN J Parenter Enteral Nutr. 2013 May-Jun; 37(3):384-91.
Miyachi T, Tsuchiya T, Oyama A, Tsuchiya T, Abe N, Sato A, Chiba Y, Kurihara S, Shibakusa T, Mikami T. PMID: 22972879.
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PubMed Mentions:
14 Fields:
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HumansCells
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Lanosterol biosynthesis: the critical role of the methyl-29 group of 2,3-oxidosqualene for the correct folding of this substrate and for the construction of the five-membered D ring. Chemistry. 2012 Oct 08; 18(41):13108-16.
Hoshino T, Chiba A, Abe N. PMID: 22933236.
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Cells
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Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells. Food Chem Toxicol. 2012 Jun; 50(6):1841-7.
Qi H, Zhu B, Abe N, Shin Y, Murata Y, Nakamura Y. PMID: 22440610.
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1 Fields:
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HumansCells
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Cytotoxicity of benzyl isothiocyanate in normal renal proximal tubular cells and its modulation by glutathione. J Agric Food Chem. 2012 Feb 22; 60(7):1887-92.
Abe N, Okuhira M, Tsutsui C, Murata Y, Nakamura Y. PMID: 22296293.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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α-Tocopherol sensitizes human leukemia HL-60 cells to apoptosis induced by benzyl isothiocyanate. Biosci Biotechnol Biochem. 2012; 76(2):381-3.
Abe N, Shimizu T, Miyoshi N, Murata Y, Nakamura Y. PMID: 22313765.
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HumansCells
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The importance of taking a history of over-the-counter medication use: a brief review and case illustration of "PRN" antihistamine dependence in a hospitalized adolescent. J Child Adolesc Psychopharmacol. 2010 Dec; 20(6):521-4.
Gracious B, Abe N, Sundberg J. PMID: 21186972; PMCID: PMC3025184.
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12 Fields:
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Humans
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Effects of KRN633, an inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase, on vascular development of placenta and fetus of mid-pregnancy in mice. J Pharmacol Sci. 2010; 112(3):290-8.
Wada Y, Ozaki H, Abe N, Nagamitsu T, Ohta H, Nakahara T, Ishii K. PMID: 20197639.
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Animals
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A Japanese boy with apparent Bohring-Opitz or "C-like" syndrome. Am J Med Genet A. 2006 Apr 15; 140(8):897-9.
Osaki M, Makita Y, Miura J, Abe N, Noguchi S, Miyamoto A. PMID: 16528754.
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PubMed Mentions:
2 Fields:
Translation:
Humans