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Patrick Maloney, MD

Title(s)Non-ACGME Fellow, Neurological Surgery
SchoolSchool of Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Outcomes in single-level posterior cervical spine surgeries performed in the sitting and prone positions. J Neurosurg Spine. 2020 Jul 03; 1-7. Himes BT, Abcejo AS, Kerezoudis P, Bhargav AG, Trelstad-Andrist K, Maloney PR, Atkinson JLD, Meyer FB, Marsh WR, Bydon M. PMID: 32619981.
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    2. ß-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell. 2020 Jun 11; 181(6):1364-1379.e14. Slosky LM, Bai Y, Toth K, Ray C, Rochelle LK, Badea A, Chandrasekhar R, Pogorelov VM, Abraham DM, Atluri N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney P, Yuan H, Li Z, Wetsel WC, Pinkerton AB, Barak LS, Caron MG. PMID: 32470395.
      View in: PubMed   Mentions: 1     Fields:    
    3. Discovery of small molecule antagonists of chemokine receptor CXCR6 that arrest tumor growth in SK-HEP-1 mouse xenografts as a model of hepatocellular carcinoma. Bioorg Med Chem Lett. 2020 02 15; 30(4):126899. Peddibhotla S, Hershberger PM, Jason Kirby R, Sugarman E, Maloney PR, Hampton Sessions E, Divlianska D, Morfa CJ, Terry D, Pinkerton AB, Smith LH, Malany S. PMID: 31882297.
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    4. Discovery of ß-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. J Med Chem. 2019 09 12; 62(17):8357-8363. Pinkerton AB, Peddibhotla S, Yamamoto F, Slosky LM, Bai Y, Maloney P, Hershberger P, Hedrick MP, Falter B, Ardecky RJ, Smith LH, Chung TDY, Jackson MR, Caron MG, Barak LS. PMID: 31390201.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Paraneoplastic syndrome or metastatic sinonasal neuroendocrine carcinoma? Clinical conundrum. Ear Nose Throat J. 2018 Oct-Nov; 97(10-11):E15-E18. Kerezoudis P, Maloney PR, McCutcheon B, Janus J, Jentoft M, Kaufmann T, Lachance DH, Van Gompel JJ, Bydon M. PMID: 30481850.
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    6. Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization. PLoS One. 2018; 13(9):e0202436. McAnally D, Siddiquee K, Gomaa A, Szabo A, Vasile S, Maloney PR, Divlianska DB, Peddibhotla S, Morfa CJ, Hershberger P, Falter R, Williamson R, Terry DB, Farjo R, Pinkerton AB, Qi X, Quigley J, Boulton ME, Grant MB, Smith LH. PMID: 30208056.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model. Bioorg Med Chem Lett. 2018 06 01; 28(10):1958-1963. Price DJ, Drewry DH, Schaller LT, Thompson BD, Reid PR, Maloney PR, Liang X, Banker P, Buckholz RG, Selley PK, McDonald OB, Smith JL, Shearer TW, Cox RF, Williams SP, Reid RA, Tacconi S, Faggioni F, Piubelli C, Sartori I, Tessari M, Wang TY. PMID: 29653895.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Corrigendum to "Coma and Stroke Following Surgical Treatment of Unruptured Intracranial Aneurysm: An American College of Surgeons National Surgical Quality Improvement Program Study" [World Neurosurgery (2016) 91:272-278]. World Neurosurg. 2018 02; 110:614-615. McCutcheon BA, Kerezoudis P, Porter AL, Rinaldo L, Murphy ME, Maloney PR, Shepherd DS, Hirshman BR, Carter BS, Lanzino G, Bydon M, Meyer FB. PMID: 29288060.
      View in: PubMed   Mentions:    Fields:    
    9. Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress. J Pharmacol Exp Ther. 2018 01; 364(1):87-96. Kirby RJ, Divlianska DB, Whig K, Bryan N, Morfa CJ, Koo A, Nguyen KH, Maloney P, Peddibhotla S, Sessions EH, Hershberger PM, Smith LH, Malany S. PMID: 29101218.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. Skull base plasmacytoma: A unique case of POEMS syndrome with a plasmacytoma causing craniocervical instability. J Clin Neurosci. 2018 Jan; 47:254-257. Gilder H, Murphy ME, Alvi MA, Kerezoudis P, Shepherd D, Maloney PR, Yaszemski MJ, Morris JM, Dispenzieri A, Matsumoto JM, Bydon M. PMID: 29100675.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Predictors of Discharge to a Nonhome Facility in Patients Undergoing Lumbar Decompression Without Fusion for Degenerative Spine Disease. Neurosurgery. 2017 Oct 01; 81(4):638-649. Murphy ME, Maloney PR, McCutcheon BA, Rinaldo L, Shepherd D, Kerezoudis P, Gilder H, Ubl DS, Crowson CS, Freedman BA, Habermann EB, Bydon M. PMID: 28486638.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Minimally invasive percutaneous approach for the management of high grade spondylolisthesis. J Neurosurg Sci. 2018 Aug; 62(4):521-522. Alvi MA, Kerezoudis P, Alamoudi A, Meyer J, Shepherd D, Maloney P, Bydon M. PMID: 28869369.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Diabetes and Back Pain: Markers of Diabetes Disease Progression Are Associated With Chronic Back Pain. Clin Diabetes. 2017 Jul; 35(3):126-131. Rinaldo L, McCutcheon BA, Gilder H, Kerezoudis P, Murphy M, Maloney P, Hassoon A, Bydon M. PMID: 28761214.
      View in: PubMed   Mentions:
    14. Increased Total Anesthetic Time Leads to Higher Rates of Surgical Site Infections in Spinal Fusions. Spine (Phila Pa 1976). 2017 Jun 01; 42(11):E687-E690. Puffer RC, Murphy M, Maloney P, Kor D, Nassr A, Freedman B, Fogelson J, Bydon M. PMID: 27683976.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Gamma knife radiosurgery for the treatment of uveal melanoma and uveal metastases. Int J Retina Vitreous. 2017; 3:17. Reynolds MM, Arnett AL, Parney IF, Kumar R, Laack NN, Maloney PR, Kozelsky TF, Garces YI, Foote RL, Pulido JS. PMID: 28560050.
      View in: PubMed   Mentions:
    16. Osteosclerosis Secondary to Metastatic Oligodendroglioma. Rare Tumors. 2017 Mar 24; 9(1):6837. Maloney PR, Yamaki VN, Kumar R, Johnson D, Hunt C, Jentoft ME, Clarke M. PMID: 28435646.
      View in: PubMed   Mentions:
    17. Full-endoscopic versus micro-endoscopic and open discectomy: A systematic review and meta-analysis of outcomes and complications. Clin Neurol Neurosurg. 2017 Mar; 154:1-12. Phan K, Xu J, Schultz K, Alvi MA, Lu VM, Kerezoudis P, Maloney PR, Murphy ME, Mobbs RJ, Bydon M. PMID: 28086154.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    18. Quantitative analysis of the effect of institutional case volume on complications after surgical clipping of unruptured aneurysms. J Neurosurg. 2017 Dec; 127(6):1297-1306. Rinaldo L, McCutcheon BA, Murphy ME, Shepherd DL, Maloney PR, Kerezoudis P, Bydon M, Lanzino G. PMID: 28059649.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Clinical and surgical management of a congenital Type II split cord malformation presenting with progressive cranial neuropathies: case report. J Neurosurg Pediatr. 2017 Mar; 19(3):349-353. Maloney PR, Murphy ME, Sullan MJ, Van Abel KM, Cofer SA, Cheville JC, Wetjen NM. PMID: 28009225.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Risk factors for dural tears: a study of elective spine surgery. Neurol Res. 2017 Feb; 39(2):97-106. Murphy ME, Kerezoudis P, Alvi MA, McCutcheon BA, Maloney PR, Rinaldo L, Shepherd D, Ubl DS, Krauss WE, Habermann EB, Bydon M. PMID: 27908218.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Allograft versus autograft in cervical and lumbar spinal fusions: an examination of operative time, length of stay, surgical site infection, and blood transfusions. J Neurosurg Sci. 2019 Feb; 63(1):11-18. Murphy ME, Mccutcheon BA, Grauberger J, Shepherd D, Maloney PR, Rinaldo L, Kerezoudis P, Fogelson JL, Nassr A, Bydon M. PMID: 27879952.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Lumbar decompression in the elderly: increased age as a risk factor for complications and nonhome discharge. J Neurosurg Spine. 2017 Mar; 26(3):353-362. Murphy ME, Gilder H, Maloney PR, McCutcheon BA, Rinaldo L, Shepherd D, Kerezoudis P, Ubl DS, Crowson CS, Krauss WE, Habermann EB, Bydon M. PMID: 27858534.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Chronic low-back pain in adult with diabetes: NHANES 2009-2010. J Diabetes Complications. 2017 01; 31(1):38-42. Hassoon A, Bydon M, Kerezoudis P, Maloney PR, Rinaldo L, Yeh HC. PMID: 27838098.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Intracranial Pressure Monitoring in Acute Liver Failure: Institutional Case Series. Neurocrit Care. 2016 08; 25(1):86-93. Maloney PR, Mallory GW, Atkinson JL, Wijdicks EF, Rabinstein AA, Van Gompel JJ. PMID: 26966022.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Predictors of 30-day perioperative morbidity and mortality of unruptured intracranial aneurysm surgery. Clin Neurol Neurosurg. 2016 Oct; 149:75-80. Kerezoudis P, McCutcheon BA, Murphy M, Rayan T, Gilder H, Rinaldo L, Shepherd D, Maloney PR, Hirshman BR, Carter BS, Bydon M, Meyer F, Lanzino G. PMID: 27490305.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Morbid obesity increases risk of morbidity and reoperation in resection of benign cranial nerve neoplasms. Clin Neurol Neurosurg. 2016 Sep; 148:105-9. Murphy ME, McCutcheon BA, Kerezoudis P, Porter A, Rinaldo L, Shepherd D, Rayan T, Maloney PR, Carter BS, Bydon M, Gompel JJ, Link MJ. PMID: 27434528.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. ACS Chem Biol. 2016 07 15; 11(7):1880-90. Barak LS, Bai Y, Peterson S, Evron T, Urs NM, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, Caron MG. PMID: 27119457.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    28. Coma and Stroke Following Surgical Treatment of Unruptured Intracranial Aneurysm: An American College of Surgeons National Surgical Quality Improvement Program Study. World Neurosurg. 2016 Jul; 91:272-8. McCutcheon BA, Kerezoudis P, Porter AL, Rinaldo L, Murphy M, Maloney P, Shepherd D, Hirshman BR, Carter BS, Lanzino G, Bydon M, Meyer F. PMID: 27108027.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Is Patient Age Associated with Perioperative Outcomes After Surgical Resection of Benign Cranial Nerve Neoplasms? World Neurosurg. 2016 May; 89:101-7. McCutcheon BA, Grauberger J, Murphy M, Kerezoudis P, Rinaldo L, Shepherd D, Maloney P, Snyder K, Carter BS, Bydon M, Van Gompel JJ, Link MJ. PMID: 26855306.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Increased Operative Time for Benign Cranial Nerve Tumor Resection Correlates with Increased Morbidity Postoperatively. J Neurol Surg B Skull Base. 2016 Aug; 77(4):350-7. Murphy M, Gilder H, McCutcheon BA, Kerezoudis P, Rinaldo L, Shepherd D, Maloney P, Snyder K, Carlson ML, Carter BS, Bydon M, Van Gompel JJ, Link MJ. PMID: 27441161.
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    31. Postoperative Delayed Cervical Palsies: Understanding the Etiology. Global Spine J. 2016 Sep; 6(6):571-83. Planchard RF, Maloney PR, Mallory GW, Puffer RC, Spinner RJ, Nassr A, Fogelson JL, Krauss WE, Clarke MJ. PMID: 27555999.
      View in: PubMed   Mentions:
    32. Predictors of Surgical Site Infection Following Craniotomy for Intracranial Neoplasms: An Analysis of Prospectively Collected Data in the American College of Surgeons National Surgical Quality Improvement Program Database. World Neurosurg. 2016 Apr; 88:350-358. McCutcheon BA, Ubl DS, Babu M, Maloney P, Murphy M, Kerezoudis P, Bydon M, Habermann EB, Parney I. PMID: 26743384.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    33. Significance of routine cerebrospinal fluid analysis in subarachnoid hemorrhage. J Neurosurg Sci. 2017 04; 61(2):117-123. Singh TD, Maloney P, Rabinstein AA, Hocker S. PMID: 26101429.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes. ACS Chem Biol. 2015 Aug 21; 10(8):1871-9. Peddibhotla S, Fontaine P, Leung CK, Maloney P, Hershberger PM, Wang Y, Bousquet MS, Luesch H, Mangravita-Novo A, Pinkerton AB, Smith LH, Malany S, Choe K. PMID: 25946346.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    35. The effect of diabetes mellitus on 30-day outcomes following single-level open lumbar microdiscectomy: an aged-matched case-control study. J Neurosurg Sci. 2017 02; 61(1):1-7. Maloney PR, Halasz SR, Mallory GW, Grassner L, Jacob JT, Nassr A, Clarke MJ. PMID: 25990296.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Attenuation of vesicular stomatitis virus infection of brain using antiviral drugs and an adeno-associated virus-interferon vector. Virology. 2015 Jan 15; 475:1-14. Wollmann G, Paglino JC, Maloney PR, Ahmadi SA, van den Pol AN. PMID: 25462341.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    37. Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). Bioorg Med Chem Lett. 2014 Jul 15; 24(14):3100-3. Sparks SM, Chen G, Collins JL, Danger D, Dock ST, Jayawickreme C, Jenkinson S, Laudeman C, Leesnitzer MA, Liang X, Maloney P, McCoy DC, Moncol D, Rash V, Rimele T, Vulimiri P, Way JM, Ross S. PMID: 24881566.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    38. Not so small vessel vasculitis. JAMA Neurol. 2013 Dec; 70(12):1578-9. Burrows AM, Maloney PR, Van Gompel JJ. PMID: 24100932.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Discovery of ML314, a Brain Penetrant Non-Peptidic ß-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor. ACS Med Chem Lett. 2013 Jul 20; 4(9):846-851. Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, Salaniwal S, Stonich D, Su Y, Mangravita-Novo A, Vicchiarelli M, Roth GP, Smith LH, Chung TD, Hanson GR, Thomas JB, Caron MG, Barak LS, Pinkerton AB. PMID: 24611085.
      View in: PubMed   Mentions:
    40. Surgically induced SMART syndrome: case report and review of the literature. World Neurosurg. 2014 Jul-Aug; 82(1-2):240.e7-12. Maloney PR, Rabinstein AA, Daniels DJ, Link MJ. PMID: 23314030.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    41. Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor. Bioorg Med Chem Lett. 2012 Nov 01; 22(21):6656-60. Maloney PR, Khan P, Hedrick M, Gosalia P, Milewski M, Li L, Roth GP, Sergienko E, Suyama E, Sugarman E, Nguyen K, Mehta A, Vasile S, Su Y, Stonich D, Nguyen H, Zeng FY, Novo AM, Vicchiarelli M, Diwan J, Chung TD, Smith LH, Pinkerton AB. PMID: 23010269.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    42. Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro. J Med Chem. 2012 Aug 23; 55(16):7262-72. Preuss J, Maloney P, Peddibhotla S, Hedrick MP, Hershberger P, Gosalia P, Milewski M, Li YL, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Roth GP, Diwan J, Chung TD, Jortzik E, Rahlfs S, Becker K, Pinkerton AB, Bode L. PMID: 22813531.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    43. Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1. J Med Chem. 2006 Nov 16; 49(23):6652-5. Whitby RJ, Dixon S, Maloney PR, Delerive P, Goodwin BJ, Parks DJ, Willson TM. PMID: 17154495.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    44. Aza-stilbenes as potent and selective c-RAF inhibitors. Bioorg Med Chem Lett. 2006 Oct 15; 16(20):5378-83. McDonald O, Lackey K, Davis-Ward R, Wood E, Samano V, Maloney P, Deanda F, Hunter R. PMID: 16890436.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    45. Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity. Bioorg Med Chem Lett. 2003 May 05; 13(9):1517-21. Sznaidman ML, Haffner CD, Maloney PR, Fivush A, Chao E, Goreham D, Sierra ML, LeGrumelec C, Xu HE, Montana VG, Lambert MH, Willson TM, Oliver WR, Sternbach DD. PMID: 12699745.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    46. 6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. J Med Chem. 2002 Aug 15; 45(17):3569-72. Pellicciari R, Fiorucci S, Camaioni E, Clerici C, Costantino G, Maloney PR, Morelli A, Parks DJ, Willson TM. PMID: 12166927.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    47. Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA. J Biol Chem. 2002 Oct 04; 277(40):37229-34. Nakahara M, Fujii H, Maloney PR, Shimizu M, Sato R. PMID: 12149270.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
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