"Cyclization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
| Descriptor ID |
D003500
|
| MeSH Number(s) |
G02.111.180 G02.607.133 G03.208
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclization".
Below are MeSH descriptors whose meaning is more specific than "Cyclization".
This graph shows the total number of publications written about "Cyclization" by people in this website by year, and whether "Cyclization" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 11 | 11 |
| 2003 | 0 | 15 | 15 |
| 2004 | 0 | 8 | 8 |
| 2005 | 0 | 8 | 8 |
| 2006 | 0 | 12 | 12 |
| 2007 | 0 | 8 | 8 |
| 2008 | 0 | 9 | 9 |
| 2009 | 0 | 13 | 13 |
| 2010 | 0 | 17 | 17 |
| 2011 | 0 | 16 | 16 |
| 2012 | 1 | 20 | 21 |
| 2013 | 0 | 15 | 15 |
| 2014 | 0 | 9 | 9 |
| 2015 | 0 | 7 | 7 |
| 2016 | 0 | 8 | 8 |
| 2017 | 0 | 5 | 5 |
| 2018 | 0 | 8 | 8 |
| 2019 | 0 | 6 | 6 |
| 2020 | 0 | 8 | 8 |
| 2021 | 0 | 5 | 5 |
| 2022 | 0 | 3 | 3 |
| 2024 | 1 | 3 | 4 |
| 2025 | 0 | 3 | 3 |
Below are the most recent publications written about "Cyclization" by people in Profiles.
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Cyclization of the Analgesic α-Conotoxin Vc1.1 With a Non-Natural Linker: Effects on Structure, Stability, and Bioactivity. J Pept Sci. 2025 Jun; 31(6):e70017.
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Rapid clearance of achiral small-molecule drugs using de novo-designed proteins and their cyclic and mirror-image variants. Nat Biomed Eng. 2025 Oct; 9(10):1775-1787.
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Characterization and Engineering of a Bisabolene Synthase Reveal an Unusual Hydride Shift and Key Residues Critical for Mono-, Bi-, and Tricyclic Sesquiterpenes Formation. J Am Chem Soc. 2025 Mar 26; 147(12):10413-10422.
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Cyclization increases bactericidal activity of arginine-rich cationic cell-penetrating peptide for Neisseria gonorrhoeae. Microbiol Spectr. 2024 Sep 03; 12(9):e0099724.
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Double Cyclization Tandem Mass for Identification and Quantification of Phosphatidylcholines Using Isobaric Six-Plex Capillary nLC-MS/MS. J Am Soc Mass Spectrom. 2024 Jul 03; 35(7):1403-1412.
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Oxidative cyclization reagents reveal tryptophan cation-π interactions. Nature. 2024 Mar; 627(8004):680-687.
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Functional and Promiscuity Studies of Three-Residue Cyclophane Forming Enzymes Show Nonnative C-C Cross-Linked Products and Leader-Dependent Cyclization. ACS Chem Biol. 2024 03 15; 19(3):774-783.
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A Synthesis of Alstonlarsine A via Alstolucines B and F Demonstrates the Chemical Feasibility of a Proposed Biogenesis. Angew Chem Int Ed Engl. 2023 01 23; 62(4):e202215098.
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Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nat Chem Biol. 2022 10; 18(10):1135-1143.
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Cyclic (amino)(barrelene)carbenes: an original family of CAACs through a novel synthetic pathway. Chem Commun (Camb). 2022 Jul 05; 58(54):7519-7521.