"Plasminogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
| Descriptor ID |
D010958
|
| MeSH Number(s) |
D08.622.610 D12.776.124.790.223.580 D12.776.377.715.182.580
|
| Concept/Terms |
Glu-Plasminogen- Glu-Plasminogen
- Glu Plasminogen
- Glutamyl Plasminogen
- Plasminogen, Glutamyl
- Glutamic Acid 1-Plasminogen
- 1-Plasminogen, Glutamic Acid
- Glutamic Acid 1 Plasminogen
|
Below are MeSH descriptors whose meaning is more general than "Plasminogen".
Below are MeSH descriptors whose meaning is more specific than "Plasminogen".
This graph shows the total number of publications written about "Plasminogen" by people in this website by year, and whether "Plasminogen" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 0 | 3 |
| 1997 | 0 | 1 | 1 |
| 1998 | 2 | 2 | 4 |
| 1999 | 1 | 2 | 3 |
| 2000 | 2 | 4 | 6 |
| 2001 | 5 | 2 | 7 |
| 2002 | 4 | 1 | 5 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 6 | 2 | 8 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 2 | 4 |
| 2010 | 1 | 1 | 2 |
| 2011 | 3 | 1 | 4 |
| 2012 | 7 | 5 | 12 |
| 2013 | 3 | 1 | 4 |
| 2014 | 2 | 2 | 4 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 3 | 2 | 5 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 4 | 0 | 4 |
| 2021 | 4 | 2 | 6 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 3 | 4 |
| 2024 | 1 | 3 | 4 |
| 2025 | 2 | 0 | 2 |
Below are the most recent publications written about "Plasminogen" by people in Profiles.
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Plasminogen and plasmin induce specialized proresolving mediators and promote efferocytosis via 5-lipoxygenase. J Thromb Haemost. 2025 Jun; 23(6):1988-1995.
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Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication. Acta Neuropathol Commun. 2025 03 18; 13(1):62.
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Exploitation of the fibrinolytic system by B-cell acute lymphoblastic leukemia and its therapeutic targeting. Nat Commun. 2024 11 20; 15(1):10059.
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Dysregulated fibrinolysis and plasmin activation promote the pathogenesis of osteoarthritis. JCI Insight. 2024 Mar 19; 9(8).
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Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT. Cell Rep. 2024 03 26; 43(3):113881.
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Atherothrombotic and thrombolytic biomarkers in incident stroke and atrial fibrillation-related stroke: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2024 03; 390:117451.
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Overexpression of Plg-RKT protects against adipose dysfunction and dysregulation of glucose homeostasis in diet-induced obese mice. Adipocyte. 2023 12; 12(1):2252729.
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Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression. Mol Oncol. 2024 Jan; 18(1):113-135.
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Crosstalk between the plasminogen/plasmin system and inflammation resolution. J Thromb Haemost. 2023 10; 21(10):2666-2678.
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Plasmin and plasminogen prevent sepsis severity by reducing neutrophil extracellular traps and systemic inflammation. JCI Insight. 2023 04 24; 8(8).