Receptors, Histamine H1

"Receptors, Histamine H1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)


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This graph shows the total number of publications written about "Receptors, Histamine H1" by people in this website by year, and whether "Receptors, Histamine H1" was a major or minor topic of these publications.
Below are the most recent publications written about "Receptors, Histamine H1" by people in Profiles.
  1. Unraveling the Structure of Meclizine Dihydrochloride with MicroED. Adv Sci (Weinh). 2024 02; 11(6):e2306435.
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  2. RNA-seq characterization of histamine-releasing mast cells as potential therapeutic target of osteoarthritis. Clin Immunol. 2022 Nov; 244:109117.
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  3. Biased agonism at histamine H1 receptor: Desensitization, internalization and MAPK activation triggered by antihistamines. Eur J Pharmacol. 2021 Apr 05; 896:173913.
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  4. Identification of inhibitors of the RGS homology domain of GRK2 by docking-based virtual screening. Life Sci. 2019 Dec 15; 239:116872.
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  5. Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation. Eur J Pharmacol. 2019 Mar 15; 847:42-52.
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  6. Mast Cell-Derived Histamine Regulates Liver Ketogenesis via Oleoylethanolamide Signaling. Cell Metab. 2019 01 08; 29(1):91-102.e5.
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  7. Histamine elicits glutamate release from cultured astrocytes. J Pharmacol Sci. 2018 Jun; 137(2):122-128.
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  8. Histamine 1 receptor-Gβγ-cAMP/PKA-CFTR pathway mediates the histamine-induced resetting of the suprachiasmatic circadian clock. Mol Brain. 2016 05 06; 9(1):49.
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  9. Histamine resets the circadian clock in the suprachiasmatic nucleus through the H1R-CaV 1.3-RyR pathway in the mouse. Eur J Neurosci. 2015 Oct; 42(7):2467-77.
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  10. RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock. Nat Commun. 2015 Apr 10; 6:6725.
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