Richard Ward

Title(s)Clinical Research Coordinator, Dean's Office
SchoolSchool of Medicine
Address155 N Fresno Street
Fresno CA 93701
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    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The M1 muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes. Proc Natl Acad Sci U S A. 2022 06 14; 119(24):e2201103119. Marsango S, Jenkins L, Pediani JD, Bradley SJ, Ward RJ, Hesse S, Biener G, Stoneman MR, Tobin AB, Raicu V, Milligan G. PMID: 35671422; PMCID: PMC9214538.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Selective phosphorylation of threonine residues defines GPR84-arrestin interactions of biased ligands. J Biol Chem. 2022 05; 298(5):101932. Marsango S, Ward RJ, Jenkins L, Butcher AJ, Al Mahmud Z, Dwomoh L, Nagel F, Schulz S, Tikhonova IG, Tobin AB, Milligan G. PMID: 35427647; PMCID: PMC9118924.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Selective xyloglucan oligosaccharide hydrolysis by a GH31 α-xylosidase from Escherichia coli. Carbohydr Polym. 2022 May 15; 284:119150. Carneiro LABC, Fuzo CA, Meleiro LP, Carli S, Barreto MQ, Lourenzoni MR, Buckeridge MS, Ward RJ. PMID: 35287891.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    4. Dictamnine, a novel c-Met inhibitor, suppresses the proliferation of lung cancer cells by downregulating the PI3K/AKT/mTOR and MAPK signaling pathways. Biochem Pharmacol. 2022 01; 195:114864. Yu J, Zhang L, Peng J, Ward R, Hao P, Wang J, Zhang N, Yang Y, Guo X, Xiang C, An S, Xu TR. PMID: 34861243.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Covalent Immobilization of Chondrostereum purpureum Endopolygalacturonase on Ferromagnetic Nanoparticles: Catalytic Properties and Biotechnological Application. Appl Biochem Biotechnol. 2022 Feb; 194(2):848-861. Carli S, Salgado JCS, Meleiro LP, Ward RJ. PMID: 34553326.
      View in: PubMed   Mentions:    Fields:    
    6. Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10. J Mol Endocrinol. 2021 09 09; 67(4):173-188. Alhallak I, Wolter KG, Castro Munoz A, Simmen FA, Ward RJ, Petty SA, Li LX, Simmen RCM. PMID: 34382943; PMCID: PMC8489570.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. The monocyte-to-lymphocyte ratio: Sex-specific differences in the tuberculosis disease spectrum, diagnostic indices and defining normal ranges. PLoS One. 2021; 16(8):e0247745. Buttle TS, Hummerstone CY, Billahalli T, Ward RJB, Barnes KE, Marshall NJ, Spong VC, Bothamley GH. PMID: 34460817; PMCID: PMC8405018.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Enhanced hydrolytic efficiency of an engineered CBM11-glucanase enzyme chimera against barley β-d-glucan extracts. Food Chem. 2021 Dec 15; 365:130460. Furtado GP, Carli S, Meleiro LP, Salgado JCS, Ward RJ. PMID: 34237573.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. The C-terminal of the α1b-adreneroceptor is a key determinant for its structure integrity and biological functions. Biosci Biotechnol Biochem. 2021 Apr 24; 85(5):1128-1139. Liu Y, Shao YT, Ward R, Ma L, Gui HX, Hao Q, Mu X, Yang Y, An S, Guo XX, Xu TR. PMID: 33693487.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    10. Plant cell wall architecture guided design of CBM3-GH11 chimeras with enhanced xylanase activity using a tandem repeat left-handed β-3-prism scaffold. Comput Struct Biotechnol J. 2021; 19:1108-1118. Pinheiro MP, Reis RAG, Dupree P, Ward RJ. PMID: 33680354; PMCID: PMC7890094.
      View in: PubMed   Mentions:
    11. Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t. J Biol Chem. 2021 Jan-Jun; 296:100139. Ward RJ, Pediani JD, Marsango S, Jolly R, Stoneman MR, Biener G, Handel TM, Raicu V, Milligan G. PMID: 33268380; PMCID: PMC7949023.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    12. Eukaryotic translation initiation factors as promising targets in cancer therapy. Cell Commun Signal. 2020 11 04; 18(1):175. Hao P, Yu J, Ward R, Liu Y, Hao Q, An S, Xu T. PMID: 33148274; PMCID: PMC7640403.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    13. A Highly Glucose Tolerant ß-Glucosidase from Malbranchea pulchella (MpBg3) Enables Cellulose Saccharification. Sci Rep. 2020 04 24; 10(1):6998. Monteiro LMO, Vici AC, Pinheiro MP, Heinen PR, de Oliveira AHC, Ward RJ, Prade RA, Buckeridge MS, Polizeli MLTM. PMID: 32332833; PMCID: PMC7181827.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    14. A Halotolerant Endo-1,4-β-Xylanase from Aspergillus clavatus with Potential Application for Agroindustrial Residues Saccharification. Appl Biochem Biotechnol. 2020 Jul; 191(3):1111-1126. Pasin TM, Salgado JCS, Scarcella ASA, de Oliveira TB, de Lucas RC, Cereia M, Rosa JC, Ward RJ, Buckeridge MS, Polizeli MLTM. PMID: 31960367.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    15. A novel Trichoderma reesei mutant RP698 with enhanced cellulase production. Braz J Microbiol. 2020 Jun; 51(2):537-545. Silva JCR, Salgado JCS, Vici AC, Ward RJ, Polizeli MLTM, Guimarães LHS, Furriel RPM, Jorge JA. PMID: 31667801; PMCID: PMC7203315.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    16. Nutrient and drought stress: implications for phenology and biomass quality in miscanthus. Ann Bot. 2019 10 29; 124(4):553-566. da Costa RMF, Simister R, Roberts LA, Timms-Taravella E, Cambler AB, Corke FMK, Han J, Ward RJ, Buckeridge MS, Gomez LD, Bosch M. PMID: 30137291; PMCID: PMC6821376.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    17. Biochemical and kinetic characterization of the recombinant GH28 Stereum purpureum endopolygalacturonase and its biotechnological application. Int J Biol Macromol. 2019 Sep 15; 137:469-474. Carli S, Meleiro LP, Ward RJ. PMID: 31242449.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. A general method to quantify ligand-driven oligomerization from fluorescence-based images. Nat Methods. 2019 06; 16(6):493-496. Stoneman MR, Biener G, Ward RJ, Pediani JD, Badu D, Eis A, Popa I, Milligan G, Raicu V. PMID: 31110281.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    19. Immobilization of a β-glucosidase and an endoglucanase in ferromagnetic nanoparticles: A study of synergistic effects. Protein Expr Purif. 2019 08; 160:28-35. Carli S, Carneiro LABC, Ward RJ, Meleiro LP. PMID: 30940468.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    20. Design, Synthesis, and Evaluation of a Diazirine Photoaffinity Probe for Ligand-Based Receptor Capture Targeting G Protein-Coupled Receptors. Mol Pharmacol. 2019 02; 95(2):196-209. Müskens FM, Ward RJ, Herkt D, van de Langemheen H, Tobin AB, Liskamp RMJ, Milligan G. PMID: 30514721; PMCID: PMC6324650.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    21. GPCR homo-oligomerization. Curr Opin Cell Biol. 2019 04; 57:40-47. Milligan G, Ward RJ, Marsango S. PMID: 30453145; PMCID: PMC7083226.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    22. Engineering the affinity of a family 11 carbohydrate binding module to improve binding of branched over unbranched polysaccharides. Int J Biol Macromol. 2018 Dec; 120(Pt B):2509-2516. Furtado GP, Lourenzoni MR, Fuzo CA, Fonseca-Maldonado R, Guazzaroni ME, Ribeiro LF, Ward RJ. PMID: 30195003.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    23. Protein Engineering Strategies to Expand CRISPR-Cas9 Applications. Int J Genomics. 2018; 2018:1652567. Ribeiro LF, Ribeiro LFC, Barreto MQ, Ward RJ. PMID: 30155473; PMCID: PMC6098869.
      View in: PubMed   Mentions: 6  
    24. Glucose tolerant and glucose stimulated β-glucosidases - A review. Bioresour Technol. 2018 Nov; 267:704-713. Salgado JCS, Meleiro LP, Carli S, Ward RJ. PMID: 30093225.
      View in: PubMed   Mentions: 21     Fields:    
    25. Characterization of a β-galactosidase from Bacillus subtilis with transgalactosylation activity. Int J Biol Macromol. 2018 Dec; 120(Pt A):279-287. Carneiro LABC, Yu L, Dupree P, Ward RJ. PMID: 30036621.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    26. Visualization of the activation of the histamine H3 receptor (H3R) using novel fluorescence resonance energy transfer biosensors and their potential application to the study of H3R pharmacology. FEBS J. 2018 06; 285(12):2319-2336. Liu Y, Zeng H, Pediani JD, Ward RJ, Chen LY, Wu N, Ma L, Tang M, Yang Y, An S, Guo XX, Hao Q, Xu TR. PMID: 29701013.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    27. Assessing the real-time activation of the cannabinoid CB1 receptor and the associated structural changes using a FRET biosensor. Int J Biochem Cell Biol. 2018 06; 99:114-124. Liu Y, Chen LY, Zeng H, Ward R, Wu N, Ma L, Mu X, Li QL, Yang Y, An S, Guo XX, Hao Q, Xu TR. PMID: 29626639.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    28. Functionalization of paramagnetic nanoparticles for protein immobilization and purification. Anal Biochem. 2018 01 01; 540-541:45-51. Carneiro LABC, Ward RJ. PMID: 29154787.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    29. Overexpression of a Cellobiose-Glucose-Halotolerant Endoglucanase from Scytalidium thermophilum. Appl Biochem Biotechnol. 2018 May; 185(1):316-333. Meleiro LP, Carli S, Fonseca-Maldonado R, da Silva Torricillas M, Zimbardi ALRL, Ward RJ, Jorge JA, Furriel RPM. PMID: 29150773.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. Engineering the GH1 β-glucosidase from Humicola insolens: Insights on the stimulation of activity by glucose and xylose. PLoS One. 2017; 12(11):e0188254. Meleiro LP, Salgado JCS, Maldonado RF, Carli S, Moraes LAB, Ward RJ, Jorge JA, Furriel RPM. PMID: 29145480; PMCID: PMC5690678.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    31. Muscarinic receptor oligomerization. Neuropharmacology. 2018 07 01; 136(Pt C):401-410. Marsango S, Ward RJ, Alvarez-Curto E, Milligan G. PMID: 29146505; PMCID: PMC6078712.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    32. Lignocellulose binding of a Cel5A-RtCBM11 chimera with enhanced β-glucanase activity monitored by electron paramagnetic resonance. Biotechnol Biofuels. 2017; 10:269. Fonseca-Maldonado R, Meleiro LP, Mendes LFS, Alves LF, Carli S, Morero LD, Basso LGM, Costa-Filho AJ, Ward RJ. PMID: 29163671; PMCID: PMC5686792.
      View in: PubMed   Mentions: 2  
    33. Spatial Intensity Distribution Analysis: Studies of G Protein-Coupled Receptor Oligomerisation. Trends Pharmacol Sci. 2018 02; 39(2):175-186. Pediani JD, Ward RJ, Marsango S, Milligan G. PMID: 29032835; PMCID: PMC5783713.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    34. Spatial intensity distribution analysis quantifies the extent and regulation of homodimerization of the secretin receptor. Biochem J. 2017 05 24; 474(11):1879-1895. Ward RJ, Pediani JD, Harikumar KG, Miller LJ, Milligan G. PMID: 28424368; PMCID: PMC5442643.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    35. A Molecular Basis for Selective Antagonist Destabilization of Dopamine D3 Receptor Quaternary Organization. Sci Rep. 2017 05 18; 7(1):2134. Marsango S, Caltabiano G, Jiménez-Rosés M, Millan MJ, Pediani JD, Ward RJ, Milligan G. PMID: 28522847; PMCID: PMC5437050.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    36. Methods used to study the oligomeric structure of G-protein-coupled receptors. Biosci Rep. 2017 04 30; 37(2). Guo H, An S, Ward R, Yang Y, Liu Y, Guo XX, Hao Q, Xu TR. PMID: 28062602; PMCID: PMC5398257.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    37. Structural determinants of the hyperalgesic activity of myotoxic Lys49-phospholipase A2. J Venom Anim Toxins Incl Trop Dis. 2017; 23:7. Zambelli VO, Chioato L, Gutierrez VP, Ward RJ, Cury Y. PMID: 28203248; PMCID: PMC5303236.
      View in: PubMed   Mentions: 3  
    38. The role of local residue environmental changes in thermostable mutants of the GH11 xylanase from Bacillus subtilis. Int J Biol Macromol. 2017 Apr; 97:574-584. Silva SB, Pinheiro MP, Fuzo CA, Silva SR, Ferreira TL, Lourenzoni MR, Nonato MC, Vieira DS, Ward RJ. PMID: 28109807.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    39. A xylose-stimulated xylanase-xylose binding protein chimera created by random nonhomologous recombination. Biotechnol Biofuels. 2016; 9:119. Ribeiro LF, Tullman J, Nicholes N, Silva SR, Vieira DS, Ostermeier M, Ward RJ. PMID: 27274356; PMCID: PMC4896006.
      View in: PubMed   Mentions: 9  
    40. Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by Subtype-selective Antagonist Drugs. J Biol Chem. 2016 Jun 17; 291(25):13132-46. Pediani JD, Ward RJ, Godin AG, Marsango S, Milligan G. PMID: 27080256; PMCID: PMC4933229.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    41. G protein-coupled receptors as promising cancer targets. Cancer Lett. 2016 07 01; 376(2):226-39. Liu Y, An S, Ward R, Yang Y, Guo XX, Li W, Xu TR. PMID: 27000991.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    42. Thermostabilization of Bacillus subtilis GH11 xylanase by surface charge engineering. Int J Biol Macromol. 2016 Jun; 87:522-8. Alponti JS, Fonseca Maldonado R, Ward RJ. PMID: 26955749.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    43. GH53 Endo-Beta-1,4-Galactanase from a Newly Isolated Bacillus licheniformis CBMAI 1609 as an Enzymatic Cocktail Supplement for Biomass Saccharification. Appl Biochem Biotechnol. 2016 Jun; 179(3):415-26. de Lima EA, Machado CB, Zanphorlin LM, Ward RJ, Sato HH, Ruller R. PMID: 26879978.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    44. Social immunity of the family: parental contributions to a public good modulated by brood size. Evol Ecol. 2016; 30:123-135. Duarte A, Cotter SC, Reavey CE, Ward RJ, De Gasperin O, Kilner RM. PMID: 26900202; PMCID: PMC4750363.
      View in: PubMed   Mentions: 6  
    45. A-Raf: A new star of the family of raf kinases. Crit Rev Biochem Mol Biol. 2015; 50(6):520-31. An S, Yang Y, Ward R, Liu Y, Guo XX, Xu TR. PMID: 26508523.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    46. Beauveria bassiana Lipase A expressed in Komagataella (Pichia) pastoris with potential for biodiesel catalysis. Front Microbiol. 2015; 6:1083. Vici AC, da Cruz AF, Facchini FD, de Carvalho CC, Pereira MG, Fonseca-Maldonado R, Ward RJ, Pessela BC, Fernandez-Lorente G, Torres FA, Jorge JA, Polizeli ML. PMID: 26500628; PMCID: PMC4595793.
      View in: PubMed   Mentions: 5  
    47. Biased signalling: the instinctive skill of the cell in the selection of appropriate signalling pathways. Biochem J. 2015 Sep 01; 470(2):155-67. Liu Y, Yang Y, Ward R, An S, Guo XX, Li W, Xu TR. PMID: 26348905.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    48. Insertion of a xylanase in xylose binding protein results in a xylose-stimulated xylanase. Biotechnol Biofuels. 2015; 8:118. Ribeiro LF, Nicholes N, Tullman J, Ribeiro LF, Fuzo CA, Vieira DS, Furtado GP, Ostermeier M, Ward RJ. PMID: 26279676; PMCID: PMC4536891.
      View in: PubMed   Mentions: 7  
    49. Regulation of oligomeric organization of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor observed by spatial intensity distribution analysis. J Biol Chem. 2015 May 15; 290(20):12844-57. Ward RJ, Pediani JD, Godin AG, Milligan G. PMID: 25825490; PMCID: PMC4432300.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    50. Increased biomass saccharification by supplementation of a commercial enzyme cocktail with endo-arabinanase from Bacillus licheniformis. Biotechnol Lett. 2015 Jul; 37(7):1455-62. Machado CB, Citadini AP, Goldbeck R, de Lima EA, Figueiredo FL, da Silva TM, Hoffmam ZB, de Sousa AS, Squina FM, de Lourdes Teixeira de Moraes Polizeli M, Ruller R, Ward RJ. PMID: 25801671.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    51. The molecular basis of oligomeric organization of the human M3 muscarinic acetylcholine receptor. Mol Pharmacol. 2015 Jun; 87(6):936-53. Liste MJ, Caltabiano G, Ward RJ, Alvarez-Curto E, Marsango S, Milligan G. PMID: 25769304.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    52. Enhanced xyloglucan-specific endo-β-1,4-glucanase efficiency in an engineered CBM44-XegA chimera. Appl Microbiol Biotechnol. 2015 Jun; 99(12):5095-107. Furtado GP, Santos CR, Cordeiro RL, Ribeiro LF, de Moraes LA, Damásio AR, Polizeli Mde L, Lourenzoni MR, Murakami MT, Ward RJ. PMID: 25605422.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    53. Raf-interactome in tuning the complexity and diversity of Raf function. FEBS J. 2015 Jan; 282(1):32-53. An S, Yang Y, Ward R, Liu Y, Guo XX, Xu TR. PMID: 25333451.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    54. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase. Biochem J. 2014 Nov 01; 463(3):413-27. Bago R, Malik N, Munson MJ, Prescott AR, Davies P, Sommer E, Shpiro N, Ward R, Cross D, Ganley IG, Alessi DR. PMID: 25177796; PMCID: PMC4209782.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    55. Synthetic biology approaches to improve biocatalyst identification in metagenomic library screening. Microb Biotechnol. 2015 Jan; 8(1):52-64. Guazzaroni ME, Silva-Rocha R, Ward RJ. PMID: 25123225; PMCID: PMC4321373.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    56. Concommitant adaptation of a GH11 xylanase by directed evolution to create an alkali-tolerant/thermophilic enzyme. Protein Eng Des Sel. 2014 Aug; 27(8):255-62. Ruller R, Alponti J, Deliberto LA, Zanphorlin LM, Machado CB, Ward RJ. PMID: 25096197.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    57. A novel thermostable xylanase GH10 from Malbranchea pulchella expressed in Aspergillus nidulans with potential applications in biotechnology. Biotechnol Biofuels. 2014; 7:115. Ribeiro LF, De Lucas RC, Vitcosque GL, Ribeiro LF, Ward RJ, Rubio MV, Damásio AR, Squina FM, Gregory RC, Walton PH, Jorge JA, Prade RA, Buckeridge MS, Polizeli Mde L. PMID: 25788980; PMCID: PMC4364333.
      View in: PubMed   Mentions: 20  
    58. Roundabout 1 exists predominantly as a basal dimeric complex and this is unaffected by binding of the ligand Slit2. Biochem J. 2014 Jul 01; 461(1):61-73. Zakrys L, Ward RJ, Pediani JD, Godin AG, Graham GJ, Milligan G. PMID: 24673457.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    59. Structural basis for glucose tolerance in GH1 β-glucosidases. Acta Crystallogr D Biol Crystallogr. 2014 Jun; 70(Pt 6):1631-9. de Giuseppe PO, Souza Tde A, Souza FH, Zanphorlin LM, Machado CB, Ward RJ, Jorge JA, Furriel Rdos P, Murakami MT. PMID: 24914974.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    60. The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution. Nucleic Acids Res. 2014 May; 42(9):6038-51. Bowman A, Hammond CM, Stirling A, Ward R, Shang W, El-Mkami H, Robinson DA, Svergun DI, Norman DG, Owen-Hughes T. PMID: 24688059; PMCID: PMC4027167.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    61. Biochemical properties of glycosylation and characterization of a histidine acid phosphatase (phytase) expressed in Pichia pastoris. Protein Expr Purif. 2014 Jul; 99:43-9. Fonseca-Maldonado R, Maller A, Bonneil E, Thibault P, Botelho-Machado C, Ward RJ, Polizeli Mde L. PMID: 24680732.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    62. Characterization of a periplasmic nitrate reductase in complex with its biosynthetic chaperone. FEBS J. 2014 Jan; 281(1):246-60. Dow JM, Grahl S, Ward R, Evans R, Byron O, Norman DG, Palmer T, Sargent F. PMID: 24314029; PMCID: PMC4159696.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    63. D-xylose detection in Escherichia coli by a xylose binding protein-dependent response. J Biotechnol. 2013 Dec; 168(4):440-5. Ribeiro LF, Bressan F, Furtado GP, Meireles F, Ward RJ. PMID: 24161920.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    64. Novel oxytocin receptor agonists and antagonists: a patent review (2002 - 2013). Expert Opin Ther Pat. 2014 Jan; 24(1):29-46. Yang Y, Li H, Ward R, Gao L, Wei JF, Xu TR. PMID: 24094047.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    65. Orexin receptors: multi-functional therapeutic targets for sleeping disorders, eating disorders, drug addiction, cancers and other physiological disorders. Cell Signal. 2013 Dec; 25(12):2413-23. Xu TR, Yang Y, Ward R, Gao L, Liu Y. PMID: 23917208.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    66. Engineering the pattern of protein glycosylation modulates the thermostability of a GH11 xylanase. J Biol Chem. 2013 Aug 30; 288(35):25522-25534. Fonseca-Maldonado R, Vieira DS, Alponti JS, Bonneil E, Thibault P, Ward RJ. PMID: 23846692; PMCID: PMC3757213.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    67. Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor. J Biol Chem. 2013 Jun 14; 288(24):17296-312. Hudson BD, Due-Hansen ME, Christiansen E, Hansen AM, Mackenzie AE, Murdoch H, Pandey SK, Ward RJ, Marquez R, Tikhonova IG, Ulven T, Milligan G. PMID: 23589301; PMCID: PMC3682533.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    68. Structural and biophysical characterisation of G protein-coupled receptor ligand binding using resonance energy transfer and fluorescent labelling techniques. Biochim Biophys Acta. 2014 Jan; 1838(1 Pt A):3-14. Ward RJ, Milligan G. PMID: 23590995.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    69. GPCR oligomerization and receptor trafficking. Methods Enzymol. 2013; 521:69-90. Ward RJ, Xu TR, Milligan G. PMID: 23351734.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    70. Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):E2675-82. Pliotas C, Ward R, Branigan E, Rasmussen A, Hagelueken G, Huang H, Black SS, Booth IR, Schiemann O, Naismith JH. PMID: 23012406; PMCID: PMC3479538.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    71. Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J. 2012 Aug 29; 31(17):3607-19. Laarman AJ, Mijnheer G, Mootz JM, van Rooijen WJ, Ruyken M, Malone CL, Heezius EC, Ward R, Milligan G, van Strijp JA, de Haas CJ, Horswill AR, van Kessel KP, Rooijakkers SH. PMID: 22850671; PMCID: PMC3433787.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    72. The bactericidal effect of human secreted group IID phospholipase A2 results from both hydrolytic and non-hydrolytic activities. Biochimie. 2012 Jun; 94(6):1437-40. Fonseca-Maldonado R, Ferreira TL, Ward RJ. PMID: 22490726.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    73. Intramolecular fluorescence resonance energy transfer (FRET) sensors of the orexin OX1 and OX2 receptors identify slow kinetics of agonist activation. J Biol Chem. 2012 Apr 27; 287(18):14937-49. Xu TR, Ward RJ, Pediani JD, Milligan G. PMID: 22389503; PMCID: PMC3340242.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    74. Characterization of suramin binding sites on the human group IIA secreted phospholipase A2 by site-directed mutagenesis and molecular dynamics simulation. Arch Biochem Biophys. 2012 Mar 01; 519(1):17-22. Aragão EA, Vieira DS, Chioato L, Ferreira TL, Lourenzoni MR, Silva SR, Ward RJ. PMID: 22248627.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    75. Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168. Biochem J. 2012 Jan 01; 441(1):95-104. Santos CR, Paiva JH, Sforça ML, Neves JL, Navarro RZ, Cota J, Akao PK, Hoffmam ZB, Meza AN, Smetana JH, Nogueira ML, Polikarpov I, Xavier-Neto J, Squina FM, Ward RJ, Ruller R, Zeri AC, Murakami MT. PMID: 21880019.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    76. Functional characterization and oligomerization of a recombinant xyloglucan-specific endo-β-1,4-glucanase (GH12) from Aspergillus niveus. Biochim Biophys Acta. 2012 Mar; 1824(3):461-7. Damásio AR, Ribeiro LF, Ribeiro LF, Furtado GP, Segato F, Almeida FB, Crivellari AC, Buckeridge MS, Souza TA, Murakami MT, Ward RJ, Prade RA, Polizeli ML. PMID: 22230786.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    77. Analysis of conformational changes in the DNA junction-resolving enzyme T7 endonuclease I on binding a four-way junction using EPR. Biochemistry. 2011 Nov 22; 50(46):9963-72. Freeman AD, Ward R, El Mkami H, Lilley DM, Norman DG. PMID: 22008089.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    78. Engineering bifunctional laccase-xylanase chimeras for improved catalytic performance. J Biol Chem. 2011 Dec 16; 286(50):43026-38. Ribeiro LF, Furtado GP, Lourenzoni MR, Costa-Filho AJ, Santos CR, Nogueira SC, Betini JA, Polizeli Mde L, Murakami MT, Ward RJ. PMID: 22006920; PMCID: PMC3234842.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    79. Active site mutants of human secreted Group IIA Phospholipase A2 lacking hydrolytic activity retain their bactericidal effect. Biochimie. 2012 Jan; 94(1):132-6. Chioato L, Aragão EA, Ferreira TL, Ward RJ. PMID: 21986368.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    80. The orexin OX(1) receptor exists predominantly as a homodimer in the basal state: potential regulation of receptor organization by both agonist and antagonist ligands. Biochem J. 2011 Oct 01; 439(1):171-83. Xu TR, Ward RJ, Pediani JD, Milligan G. PMID: 21770891.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    81. Heteromultimerization of cannabinoid CB(1) receptor and orexin OX(1) receptor generates a unique complex in which both protomers are regulated by orexin A. J Biol Chem. 2011 Oct 28; 286(43):37414-28. Ward RJ, Pediani JD, Milligan G. PMID: 21908614; PMCID: PMC3199489.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    82. Conformation analysis of a surface loop that controls active site access in the GH11 xylanase A from Bacillus subtilis. J Mol Model. 2012 Apr; 18(4):1473-9. Vieira DS, Ward RJ. PMID: 21785938.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    83. Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding. Mol Biosyst. 2011 Jul; 7(7):2189-95. Souza TA, Trindade DM, Tonoli CC, Santos CR, Ward RJ, Arni RK, Oliveira AH, Murakami MT. PMID: 21528129.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    84. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol Pharmacol. 2011 Jul; 80(1):163-73. Smith NJ, Ward RJ, Stoddart LA, Hudson BD, Kostenis E, Ulven T, Morris JC, Tränkle C, Tikhonova IG, Adams DR, Milligan G. PMID: 21498659; PMCID: PMC3127537.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    85. Ligand-induced internalization of the orexin OX(1) and cannabinoid CB(1) receptors assessed via N-terminal SNAP and CLIP-tagging. Br J Pharmacol. 2011 Mar; 162(6):1439-52. Ward RJ, Pediani JD, Milligan G. PMID: 21175569; PMCID: PMC3058174.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    86. The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation. Mol Cell. 2011 Feb 18; 41(4):398-408. Bowman A, Ward R, Wiechens N, Singh V, El-Mkami H, Norman DG, Owen-Hughes T. PMID: 21329878; PMCID: PMC3093613.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    87. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. J Biol Chem. 2011 Mar 25; 286(12):10628-40. Schmidt J, Smith NJ, Christiansen E, Tikhonova IG, Grundmann M, Hudson BD, Ward RJ, Drewke C, Milligan G, Kostenis E, Ulven T. PMID: 21220428; PMCID: PMC3060514.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    88. Using the Flp-In™ T-Rex™ system to regulate GPCR expression. Methods Mol Biol. 2011; 746:21-37. Ward RJ, Alvarez-Curto E, Milligan G. PMID: 21607850.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    89. A practical teaching course in directed protein evolution using the green fluorescent protein as a model. Biochem Mol Biol Educ. 2011 Jan-Feb; 39(1):21-7. Ruller R, Silva-Rocha R, Silva A, Cruz Schneider MP, Ward RJ. PMID: 21433249.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    90. Ligand regulation of the quaternary organization of cell surface M3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogeneous time-resolved FRET. J Biol Chem. 2010 Jul 23; 285(30):23318-30. Alvarez-Curto E, Ward RJ, Pediani JD, Milligan G. PMID: 20489201; PMCID: PMC2906324.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    91. A nurse-led response to unmet needs of homeless migrants in inner London. Br J Nurs. 2010 Jan 14-27; 19(1):36-41. Collinson S, Ward R. PMID: 20081711.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    92. Probing the (H3-H4)2 histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling. Nucleic Acids Res. 2010 Jan; 38(2):695-707. Bowman A, Ward R, El-Mkami H, Owen-Hughes T, Norman DG. PMID: 19914933; PMCID: PMC2810997.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    93. Purification and biochemical characterization of a novel alpha-glucosidase from Aspergillus niveus. Antonie Van Leeuwenhoek. 2009 Nov; 96(4):569-78. da Silva TM, Michelin M, Damásio AR, Maller A, Almeida FB, Ruller R, Ward RJ, Rosa JC, Jorge JA, Terenzi HF, Polizeli Mde L. PMID: 19757138.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    94. Production, purification, crystallization and preliminary X-ray diffraction studies of the nucleoside diphosphate kinase b from Leishmania major. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Nov 01; 65(Pt 11):1116-9. Tonoli CC, Vieira PS, Ward RJ, Arni RK, de Oliveira AH, Murakami MT. PMID: 19923730; PMCID: PMC2777038.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    95. Shared structural determinants for the calcium-independent liposome membrane permeabilization and sarcolemma depolarization in Bothropstoxin-I, a LYS49-PLA(2) from the venom of Bothrops jararacussu. Int J Biochem Cell Biol. 2009 Dec; 41(12):2588-93. Aragão EA, Randazzo-Moura P, Rostelato-Ferreira S, Rodrigues-Simioni L, Ward RJ. PMID: 19729073.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    96. Properties of a purified thermostable glucoamylase from Aspergillus niveus. J Ind Microbiol Biotechnol. 2009 Dec; 36(12):1439-46. da Silva TM, Maller A, Damásio AR, Michelin M, Ward RJ, Hirata IY, Jorge JA, Terenzi HF, de Polizeli ML. PMID: 19697071.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    97. The interaction of bothropstoxin-I (Lys49-PLA(2)) with liposome membranes. Toxicon. 2009 Sep 15; 54(4):525-30. Ferreira TL, Ward RJ. PMID: 19500612.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    98. Reduced pH induces an inactive non-native conformation of the monomeric bothropstoxin-I (Lys49-PLA2). Toxicon. 2009 Sep 01; 54(3):373-8. de Oliveira AH, Ferreira TL, Ward RJ. PMID: 19450617.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    99. Characterization of temperature dependent and substrate-binding cleft movements in Bacillus circulans family 11 xylanase: a molecular dynamics investigation. Biochim Biophys Acta. 2009 Oct; 1790(10):1301-6. Vieira DS, Degrève L, Ward RJ. PMID: 19409448.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    100. Refolding and purification of the human secreted group IID phospholipase A2 expressed as inclusion bodies in Escherichia coli. Protein Expr Purif. 2009 Oct; 67(2):82-7. Fonseca RG, Ferreira TL, Ward RJ. PMID: 19376232.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    101. Mapping of suramin binding sites on the group IIA human secreted phospholipase A2. Bioorg Chem. 2009 Apr; 37(2):41-5. Vieira DS, Aragão EA, Lourenzoni MR, Ward RJ. PMID: 19251299.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    102. Selectivity and functional consequences of interactions of family A G protein-coupled receptors with neurochondrin and periplakin. J Neurochem. 2009 Apr; 109(1):182-92. Ward RJ, Jenkins L, Milligan G. PMID: 19166508.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    103. The association of Na,K-ATPase subunits studied by circular dichroism, surface tension and dilatational elasticity. J Colloid Interface Sci. 2008 Sep 15; 325(2):478-84. Rigos CF, Nobre TM, Zaniquelli ME, Ward RJ, Ciancaglini P. PMID: 18597766.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    104. Thermostable variants of the recombinant xylanase A from Bacillus subtilis produced by directed evolution show reduced heat capacity changes. Proteins. 2008 Mar; 70(4):1280-93. Ruller R, Deliberto L, Ferreira TL, Ward RJ. PMID: 17876824.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    105. Parents influence asymmetric sibling competition: experimental evidence with partially dependent young. Ecology. 2007 Dec; 88(12):3174-82. Smiseth PT, Ward RJ, Moore AJ. PMID: 18229851.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    106. Permeabilization of E. coli K12 inner and outer membranes by bothropstoxin-I, A LYS49 phospholipase A2 from Bothrops jararacussu. Toxicon. 2008 Mar 15; 51(4):538-46. Aragão EA, Chioato L, Ward RJ. PMID: 18160090.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    107. Insights on calcium-independent phospholipid membrane damage by Lys49-PLA2 using tryptophan scanning mutagenesis of bothropstoxin-I from Bothrops jararacussu. Biochimie. 2008 Sep; 90(9):1397-406. Ferreira TL, Ruller R, Chioato L, Ward RJ. PMID: 18036350.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    108. Purification and biochemical characterization of a thermostable extracellular glucoamylase produced by the thermotolerant fungus Paecilomyces variotii. J Ind Microbiol Biotechnol. 2008 Jan; 35(1):17-25. Michelin M, Ruller R, Ward RJ, Moraes LA, Jorge JA, Terenzi HF, Polizeli Mde L. PMID: 17938981.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    109. Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A2 by scanning alanine mutagenesis. Biochim Biophys Acta. 2007 May; 1768(5):1247-57. Chioato L, Aragão EA, Lopes Ferreira T, Medeiros AI, Faccioli LH, Ward RJ. PMID: 17346668.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    110. An ultraviolet photoacoustic spectroscopy study of the interaction between Lys49-phospholipase A2 and amphiphilic molecules. Biochem Biophys Res Commun. 2007 Feb 23; 353(4):889-94. Bugs MR, Bortoleto-Bugs RK, Cornélio ML, Ward RJ. PMID: 17210121.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    111. Interaction of neurochondrin with the melanin-concentrating hormone receptor 1 interferes with G protein-coupled signal transduction but not agonist-mediated internalization. J Biol Chem. 2006 Oct 27; 281(43):32496-507. Francke F, Ward RJ, Jenkins L, Kellett E, Richter D, Milligan G, Bächner D. PMID: 16945926.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    112. Molecular modeling of the human eukaryotic translation initiation factor 5A (eIF5A) based on spectroscopic and computational analyses. Biochem Biophys Res Commun. 2006 Sep 01; 347(3):634-40. Costa-Neto CM, Parreiras-E-Silva LT, Ruller R, Oliveira EB, Miranda A, Oliveira L, Ward RJ. PMID: 16842744.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    113. Subproteomic analysis of soluble proteins of the microsomal fraction from two Leishmania species. Comp Biochem Physiol Part D Genomics Proteomics. 2006 Sep; 1(3):300-8. de Oliveira AH, Ruiz JC, Cruz AK, Greene LJ, Rosa JC, Ward RJ. PMID: 20483262.
      View in: PubMed   Mentions: 8     Fields:    
    114. Expression in E. coli and purification of the nucleoside diphosphate kinase b from Leishmania major. Protein Expr Purif. 2006 Oct; 49(2):244-50. de Oliveira AH, Ruiz JC, Cruz AK, Greene LJ, Rosa JC, Ward RJ. PMID: 16809050.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    115. Influence of aqueous aluminium on the immune system of the freshwater crayfish Pacifasticus leniusculus. Aquat Toxicol. 2006 May 01; 77(2):222-8. Ward RJ, McCrohan CR, White KN. PMID: 16436302.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    116. Efficient constitutive expression of Bacillus subtilis xylanase A in Escherichia coli DH5alpha under the control of the Bacillus BsXA promoter. Biotechnol Appl Biochem. 2006 Jan; 43(Pt 1):9-15. Ruller R, Rosa JC, Faça VM, Greene LJ, Ward RJ. PMID: 15982188.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    117. Purification and characterization of two xylanases from alkalophilic and thermophilic Bacillus licheniformis 77-2. Appl Biochem Biotechnol. 2006; 129-132:289-302. Damiano VB, Ward R, Gomes E, Alves-Prado HF, Da Silva R. PMID: 16915648.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    118. Lipid bilayer stabilization of the Na,K-ATPase reconstituted in DPPC/DPPE liposomes. Cell Biochem Biophys. 2006; 44(3):438-45. Rigos CF, de Lima Santos H, Ward RJ, Ciancaglini P. PMID: 16679531.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    119. Functional interactions between the alpha1b-adrenoceptor and Galpha11 are compromised by de-palmitoylation of the G protein but not of the receptor. Cell Signal. 2006 Aug; 18(8):1244-51. Novotny J, Durchankova D, Ward RJ, Carrillo JJ, Svoboda P, Milligan G. PMID: 16297597.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    120. Correlation of temperature induced conformation change with optimum catalytic activity in the recombinant G/11 xylanase A from Bacillus subtilis strain 168 (1A1). FEBS Lett. 2005 Nov 21; 579(28):6505-10. Murakami MT, Arni RK, Vieira DS, Degrève L, Ruller R, Ward RJ. PMID: 16289057.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    121. A key serine for the GTPase-activating protein function of regulator of G protein signaling proteins is not a general target for 14-3-3 interactions. Mol Pharmacol. 2005 Dec; 68(6):1821-30. Ward RJ, Milligan G. PMID: 16160139.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    122. Expression and characterization of HlyX hemolysin from Leptospira interrogans serovar Copenhageni: potentiation of hemolytic activity by LipL32. Biochem Biophys Res Commun. 2005 Aug 12; 333(4):1341-7. Hauk P, Negrotto S, Romero EC, Vasconcellos SA, Genovez ME, Ward RJ, Schattner M, Goméz RM, Ho PL. PMID: 15990088.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    123. Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid. Biochimie. 2005 Feb; 87(2):161-7. Watanabe L, Soares AM, Ward RJ, Fontes MR, Arni RK. PMID: 15760708.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    124. A molecular mechanism for Lys49-phospholipase A2 activity based on ligand-induced conformational change. J Biol Chem. 2005 Feb 25; 280(8):7326-35. Ambrosio AL, Nonato MC, de Araújo HS, Arni R, Ward RJ, Ownby CL, de Souza DH, Garratt RC. PMID: 15596433.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    125. Ontogenetic changes in Phoneutria nigriventer (Araneae, Ctenidae) spider venom. Toxicon. 2004 Nov; 44(6):635-40. Herzig V, Ward RJ, Dos Santos WF. PMID: 15501289.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    126. Activation of Ca2+-independent membrane-damaging activity in Lys49-phospholipase A2 promoted by amphiphilic molecules. Biochem Biophys Res Commun. 2004 Sep 17; 322(2):364-72. Bortoleto-Bugs RK, Neto AA, Ward RJ. PMID: 15325239.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    127. Topology of the substrate-binding site of a Lys49-phospholipase A2 influences Ca2+-independent membrane-damaging activity. Biochem J. 2004 Aug 15; 382(Pt 1):191-8. Sá JM, Chioato L, Ferreira TL, De Oliveira AH, Ruller R, Rosa JC, Greene LJ, Ward RJ. PMID: 15147240; PMCID: PMC1133930.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    128. Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction. Mol Pharmacol. 2004 Aug; 66(2):250-9. Heydorn A, Ward RJ, Jorgensen R, Rosenkilde MM, Frimurer TM, Milligan G, Kostenis E. PMID: 15266015.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    129. Phe120 contributes to the regiospecificity of cytochrome P450 2D6: mutation leads to the formation of a novel dextromethorphan metabolite. Biochem J. 2004 Jun 01; 380(Pt 2):353-60. Flanagan JU, Maréchal JD, Ward R, Kemp CA, McLaughlin LA, Sutcliffe MJ, Roberts GC, Paine MJ, Wolf CR. PMID: 14992686; PMCID: PMC1224184.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    130. The biological activity in mammals and insects of the nucleosidic fraction from the spider Parawixia bistriata. Toxicon. 2004 Mar 15; 43(4):375-83. Rodrigues MC, Guizzo R, Gobbo-Neto L, Ward RJ, Lopes NP, dos Santos WF. PMID: 15051400.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    131. Analysis of function of receptor-G-protein and receptor-RGS fusion proteins. Methods Mol Biol. 2004; 259:225-47. Ward RJ, Milligan G. PMID: 15250496.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    132. Mapping structural determinants of biological activities in snake venom phospholipases A2 by sequence analysis and site directed mutagenesis. Toxicon. 2003 Dec 15; 42(8):869-83. Chioato L, Ward RJ. PMID: 15019488.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    133. Spectroscopic characterization and structural modeling of prolamin from maize and pearl millet. Eur Biophys J. 2004 Jul; 33(4):335-43. Bugs MR, Forato LA, Bortoleto-Bugs RK, Fischer H, Mascarenhas YP, Ward RJ, Colnago LA. PMID: 14508615.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    134. Concerted stimulation and deactivation of pertussis toxin-sensitive G proteins by chimeric G protein-coupled receptor-regulator of G protein signaling 4 fusion proteins: analysis of the contribution of palmitoylated cysteine residues to the GAP activity of RGS4. J Neurochem. 2003 Jun; 85(5):1289-98. Bahia DS, Sartania N, Ward RJ, Cavalli A, Jones TL, Druey KM, Milligan G. PMID: 12753087.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    135. Mechanism of action of Gq to inhibit G beta gamma modulation of CaV2.2 calcium channels: probed by the use of receptor-G alpha tandems. Mol Pharmacol. 2003 Apr; 63(4):832-43. Bertaso F, Ward RJ, Viard P, Milligan G, Dolphin AC. PMID: 12644584.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    136. Palmitoylation regulates regulator of G-protein signaling (RGS) 16 function. II. Palmitoylation of a cysteine residue in the RGS box is critical for RGS16 GTPase accelerating activity and regulation of Gi-coupled signalling. J Biol Chem. 2003 May 23; 278(21):19309-16. Osterhout JL, Waheed AA, Hiol A, Ward RJ, Davey PC, Nini L, Wang J, Milligan G, Jones TL, Druey KM. PMID: 12642592.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    137. Structural and functional analysis of BmjMIP, a phospholipase A2 myotoxin inhibitor protein from Bothrops moojeni snake plasma. Biochem Biophys Res Commun. 2003 Mar 07; 302(2):193-200. Soares AM, Marcussi S, Stábeli RG, França SC, Giglio JR, Ward RJ, Arantes EC. PMID: 12604331.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    138. Chemical denaturation of a homodimeric lysine-49 phospholipase A2: a stable dimer interface and a native monomeric intermediate. Arch Biochem Biophys. 2003 Mar 01; 411(1):112-20. Ruller R, Ferreira TL, de Oliveira AH, Ward RJ. PMID: 12590929.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    139. Isolation, purification, and physicochemical characterization of a D-galactose-binding lectin from seeds of Erythrina speciosa. Arch Biochem Biophys. 2003 Feb 15; 410(2):222-9. Konozy EH, Bernardes ES, Rosa C, Faca V, Greene LJ, Ward RJ. PMID: 12573281.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    140. Purification, some properties of a D-galactose-binding leaf lectin from Erythrina indica and further characterization of seed lectin. Biochimie. 2002 Oct; 84(10):1035-43. Konozy EH, Mulay R, Faca V, Ward RJ, Greene LJ, Roque-Barriera MC, Sabharwal S, Bhide SV. PMID: 12504284.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    141. Distinct sites for myotoxic and membrane-damaging activities in the C-terminal region of a Lys49-phospholipase A2. Biochem J. 2002 Sep 15; 366(Pt 3):971-6. Chioato L, De Oliveira AH, Ruller R, Sá JM, Ward RJ. PMID: 12079495; PMCID: PMC1222840.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    142. Active-site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis. Biochem J. 2002 Feb 15; 362(Pt 1):89-96. Ward RJ, Chioato L, de Oliveira AH, Ruller R, Sá JM. PMID: 11829743; PMCID: PMC1222363.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    143. Reciprocal mutations of highly conserved residues in transmembrane helices 2 and 7 of the alpha(2A)-adrenoceptor restore agonist activation of G(i1)alpha. Cell Signal. 2002 Feb; 14(2):139-44. Ward RJ, Milligan G. PMID: 11781138.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    144. Intrathecal methadone: a dose-response study and comparison with intrathecal morphine 0.5 mg. Pain. 1990 Nov; 43(2):141-148. Jacobson L, Chabal C, Brody MC, Ward RJ, Wasse L. PMID: 2087326.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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