Subhashini Ladella, MD

Title(s)Clinical Professor, Ob/Gyn - Fresno
SchoolSchool of Medicine
AddressLocation Required, #001
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    Collapse Biography 
    Collapse Education and Training
    Harbor UCLA Medical Center, California06/2002Maternal Fetal Medicine Fellowship
    Providence Hospital, Affiliation: Wayne State University, Michigan06/1999OBGYN Residency
    Providence Hospital, Affiliation: Wayne State Unversity, Michigan06/1995Transitional Year Residency
    Christian Medical College and Hospital, Tamil Nadu06/1988Internship
    Christian Medical College and Hospital, Tamil NaduMD06/1986Doctor of Medicine
    Collapse Awards and Honors
    Providence Hospital1998Outstanding Resident Teacher
    Providence Hospital1999Mandelbaum Award for Clinical Obstetrics: OBGYN Research
    United Hospital2014Hospital Outstanding Patient Experience Award
    Allina Health2014Allina Advanced Training Project Certification
    March of Dimes Annual Conference2017Winning Poster of the 2017 March of Dimes Annual Conference Poster Session

    Collapse Overview 
    Collapse Overview
    Subhashini Ladella M.D., FACOG
    Clinical Professor, UCSF
    Director, Maternal-Fetal Medicine

    Subhashini Ladella, M.D., FACOG, is a Maternal Fetal Medicine subspecialist. She is board certified in Obstetrics and Gynecology with an additional board certification in Maternal Fetal Medicine.

    As the Director of Perinatology for Community Medical Centers, Dr. Ladella brings a wealth of experience in the field of high risk obstetrics to patients here in the Central Valley. Dr. Ladella has extensive experience in the comprehensive outpatient and inpatient management of complicated pregnancies. Dr. Ladella’s practice includes the following services: prenatal screening, prenatal diagnosis, targeted ultrasound examinations, fetal echocardiography, perinatal consultations and invasive diagnostic as well as therapeutic fetal therapies such as: amniocentesis, cordocentesis and intrauterine fetal transfusions.

    In addition to her practice, Dr. Ladella is actively involved in medical student and resident teaching and training along with conducting clinical research with UCSF Fresno’s Ob/Gyn residency program’s Division of Maternal Fetal Medicine. Her research areas of interest include: preterm labor, preeclampsia and thrombophilia in pregnancy.
    Dr. Ladella has many peer-reviewed scientific publications and has been invited to present her work at multiple national and international scientific meetings.

    Dr. Ladella completed her Ob/Gyn residency training at Providence Hospital, affiliated with Wayne State University in Detroit Michigan and her Fellowship in Maternal Fetal Medicine at Harbor-UCLA Medical Center.

    Dr. Ladella is a member of various professional organizations including the Society of Maternal Fetal Medicine, the American College of Obstetrics and Gynecology, the American Institute of Ultrasound Medicine, the American Medical Association and the Christian Medical and Dental Society.

    Collapse Research 
    Collapse Research Activities and Funding
    The Effects of Amniotic Fluid Index on Latency Period and Adverse Pregnancy Outcomes in Patients with Preterm Premature Rupture of Membranes
    UCSF California Preterm Birth Initiative Feb 1, 2018 - Jan 31, 2019
    Role: PI
    Description: Understanding and reducing barriers to utilization of an evidence based preterm birth prevention with the use of Progesterone (17P) intervention in Fresno County$ 50,000 total.
    Screening of Environmental Chemicals in Central California Pregnant Women
    California Office of Environment Health Hazard Assessment Jun 1, 2017 - Dec 31, 2018
    Role: Co-Investigator; PI for UCSF Fresno
    Description: Fresno has been identified as a highly impacted community due to high exposures to multiple pollutants and social stressors such as poverty from CalEnviroScreen, a tool developed by the California Environmental Protection Agency. This pilot project will focus on better understanding chemical exposures at a local scale during vulnerable periods of development, in particular pregnancy.
    Predicting response to progesterone therapy in women with recurrent spontaneous preterm birth using machine learning on electronic medical records
    UCSF Research Allocation Program Jun 1, 2017 - May 31, 2018
    Role: Co Principal Investigator
    Description: Preterm birth (PTB) is a significant cause of neonatal morbidity and mortality. The American College ofObstetricians and Gynecologists recommends progesterone supplementation to women with either a prior spontaneous PTB or an incidental finding of short cervical length. Unfortunately, many of these high-risk women will deliver before 34 weeks of gestation despite progesterone therapy. Correctly identifying those with high likelihood of response to progesterone is the key to correctly utilizing limited resources. This project aims to use apply state-of-art machine learning computation to study the biologicalbehaviors of women with high-risk for PTB using their electronic medical records.
    Perceptions and Availability of postpartum contraception among women and health care providers following preterm birth
    UCSF California Preterm Birth Initiative Jul 1, 2016 - Oct 31, 2018
    Role: Co Investigator; PI at UCSF Fresno

    Collapse ORNG Applications 
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy. Metabolites. 2023 May 31; 13(6). Zhang Y, Sylvester KG, Jin B, Wong RJ, Schilling J, Chou CJ, Han Z, Luo RY, Tian L, Ladella S, Mo L, Maric I, Blumenfeld YJ, Darmstadt GL, Shaw GM, Stevenson DK, Whitin JC, Cohen HJ, McElhinney DB, Ling XB. PMID: 37367874; PMCID: PMC10301596.
      View in: PubMed   Mentions: 1  
    2. Investigating geographic differences in environmental chemical exposures in maternal and cord sera using non-targeted screening and silicone wristbands in California. J Expo Sci Environ Epidemiol. 2023 07; 33(4):548-557. Goin DE, Abrahamsson D, Wang M, Park JS, Sirota M, Morello-Frosch R, DeMicco E, Trowbridge J, August L, O'Connell S, Ladella S, Zlatnik MG, Woodruff TJ. PMID: 35449448; PMCID: PMC9585116.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    3. Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation. BMJ Open. 2021 11 25; 11(11):e050963. Huang Q, Hao S, You J, Yao X, Li Z, Schilling J, Thyparambil S, Liao WL, Zhou X, Mo L, Ladella S, Davies-Balch SR, Zhao H, Fan D, Whitin JC, Cohen HJ, McElhinney DB, Wong RJ, Shaw GM, Stevenson DK, Sylvester KG, Ling XB. PMID: 34824115; PMCID: PMC8627403.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    4. First Trimester Diagnosis of Placenta Accreta Spectrum resulting in Spontaneous Uterine Rupture: A Case Report. Journal of Case Reports and Images in Obstetrics and Gynecology. 2021; Article ID: 100078Z08SL2021. Ladella S, Ng S. View Publication.
    5. Understanding barriers to utilization of 17-hydroxyprogesterone caproate and other interventions to prevent preterm birth in Fresno County, California. Perinatal Journal. 2021; 2(29):155-164. Ladella S, Shaver A, Pacheco-Werner T, Cortez C, Novack M, Wiemann A, Kuppermann M. View Publication.
    6. The effects of oligohydramnios on perinatal outcomes after preterm premature rupture of membranes. Perinatal Journal 2021;29(0):27-32 DOI: 10.2399/prn.21.0291005. 2021; ( March 30,). Subhashini Ladella, David Lee, Fatemeh Abbasi, Brian Morgan. View Publication.
    7. Maternal and perinatal outcomes in high compared to low risk pregnancies complicated by severe acute respiratory syndrome coronavirus 2 infection (phase 2): the World Association of Perinatal Medicine working group on coronavirus disease 2019. Am J Obstet Gynecol MFM. 2021 07; 3(4):100329. D'Antonio F, Sen C, Mascio DD, Galindo A, Villalain C, Herraiz I, Arisoy R, Ovayolu A, Eroglu H, Canales MG, Ladella S, Cojocaru L, Turan O, Turan S, Hadar E, Brzezinski-Sinai NA, Dollinger S, Uyaniklar O, Ocakouglu SR, Atak Z, Premru-Srsen T, Kornhauser-Cerar L, Druškovic M, Ples L, Gündüz R, Agaçayak E, Schvartzman JA, Malbran MN, Liberati M, Sebastiano FD, Oronzi L, Cerra C, Buca D, Cagnacci A, Ramone A, Barra F, Carosso A, Benedetto C, Cosma S, Pintiaux A, Daelemans C, Costa E, Özel A, Muhçu M, Lopez JSJ, Alvarado C, Piqueras AL, Oliva DE, Schera GBL, Volpe N, Frusca T, Samardjiski I, Simeonova S, Papestiev IA, Hojman J, Turkcuoglu I, Cromi A, Laganà AS, Ghezzi F, Sirico A, Familiari A, Scambia G, Sukhikh ZKGT, Gorina KA, de Sa RAM, Vaz M, Feuerschuette OHM, Gatta AND, Youssef A, Donna GD, Martinez-Varea A, Loscalzo G, Morales Roselló J, Stefanovic V, Nupponen I, Nelskylä K, Ayala R, Molpeceres RG, Vázquez AP, Sandri F, Cataneo I, Lenzi M, Haberal ET, Huertas E, Sanchez A, Arango P, Bermejo A, Alcantara MMG, Göynümer G, Okuyan E, Madalina C, Guisan AC, Schulte AM, Esposito V, De Robertis V, Zdjelar S, Lackovic M, Mihajlovic S, Jekova N, Saccone G, Aslan MM, Dedda MCD, Chalid M, Canache JEM, Daskalakis G, Antsaklis P, Vega EC, Cueto E, Taccaliti C, Aykanat Y, Özlem Genç S, Froessler B, Radulova PA, Morano D, Bianchi B, Marino MGL, Meccariello G, Rohatgi B, Schiattarella A, Morlando M, Colacurci N, Villasco A, Biglia N, Marques ALS, Gatti A, Luvero D, Angioli R, Pittaro A, Lila A, Zlatohlávková B, On the behalf of the World Association of Perinatal Medicine working group on coronavirus disease 20. PMID: 33621713; PMCID: PMC7896113.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    8. Maternal metabolic profiling to assess fetal gestational age and predict preterm delivery: a two-centre retrospective cohort study in the US. BMJ Open. 2020 12 02; 10(12):e040647. Sylvester KG, Hao S, You J, Zheng L, Tian L, Yao X, Mo L, Ladella S, Wong RJ, Shaw GM, Stevenson DK, Cohen HJ, Whitin JC, McElhinney DB, Ling XB. PMID: 33268420; PMCID: PMC7713207.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Experiences with Prenatal and Postpartum Contraceptive Services among Women with a Preterm Birth. Womens Health Issues. 2020 May - Jun; 30(3):184-190. Thiel de Bocanegra H, Kenny J, Sayler K, Turocy M, Ladella S. PMID: 31859188.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Maternal plasma hypertonicity is accentuated in the postterm rat. Am J Obstet Gynecol. 2003 Nov; 189(5):1439-44. Ladella SJ, Desai M, Cho Y, Ross MG. PMID: 14634583.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    11. Reversal of pregnancy-mediated plasma hypotonicity in the near-term rat. J Matern Fetal Neonatal Med. 2003 Mar; 13(3):197-202. Desai M, Ladella S, Ross MG. PMID: 12820842.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    12. 554 Maternal plasma hypertonicity is increased in postterm pregnant rats. American Journal of Obstetrics and Gynecology. 2001 Dec 1; 185(6):s231. Ladella LS, Desai DM, Cho CY, Kallichanda KN, Ross RM. .
      View in: Publisher Site   Mentions:
    13. Does exercise affect female hamster gonadotropins by reducing estradiol negative feedback? Physiol Behav. 1999 Jan 1-15; 65(4-5):855-61. Borer KT, Pieper D, Ali H, Ladella S, Lobocki C. PMID: 10073492.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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